silicon and epibatidine

silicon has been researched along with epibatidine* in 1 studies

Other Studies

1 other study(ies) available for silicon and epibatidine

ArticleYear
Functionalization of the alicyclic skeleton of epibatidine: synthesis and nicotinic acetylcholine receptor binding affinities of epibatidine analogues.
    Organic & biomolecular chemistry, 2003, Nov-21, Volume: 1, Issue:22

    A novel method for the epimerization of endo-2-(6-chloro-3-pyridyl)-7-azabicyclo[2.2.1]heptan-3-one (12) on silica gel was developed and used as the key step to synthesize functionalized analogues of epibatidine which were evaluated for their nicotine receptor subtype selectivity in binding studies.

    Topics: Analgesics, Non-Narcotic; Animals; Anura; Bridged Bicyclo Compounds, Heterocyclic; Kinetics; Models, Chemical; Models, Molecular; Protein Binding; Pyridines; Receptors, Nicotinic; Silicon; Tomography, Emission-Computed; X-Rays

2003