silicon has been researched along with epibatidine* in 1 studies
1 other study(ies) available for silicon and epibatidine
Article | Year |
---|---|
Functionalization of the alicyclic skeleton of epibatidine: synthesis and nicotinic acetylcholine receptor binding affinities of epibatidine analogues.
A novel method for the epimerization of endo-2-(6-chloro-3-pyridyl)-7-azabicyclo[2.2.1]heptan-3-one (12) on silica gel was developed and used as the key step to synthesize functionalized analogues of epibatidine which were evaluated for their nicotine receptor subtype selectivity in binding studies. Topics: Analgesics, Non-Narcotic; Animals; Anura; Bridged Bicyclo Compounds, Heterocyclic; Kinetics; Models, Chemical; Models, Molecular; Protein Binding; Pyridines; Receptors, Nicotinic; Silicon; Tomography, Emission-Computed; X-Rays | 2003 |