silicon and 4-hydroxymethyl-3-3-4-trimethyl-1-2-dioxetane

silicon has been researched along with 4-hydroxymethyl-3-3-4-trimethyl-1-2-dioxetane* in 1 studies

Other Studies

1 other study(ies) available for silicon and 4-hydroxymethyl-3-3-4-trimethyl-1-2-dioxetane

Article	Year
Induction of the SOS function sfiA in E. coli by systems which generate triplet ketones. Mutation research, 1988, Volume: 198, Issue:1 Generation of triplet ketones, either chemically through thermal decomposition of 3-hydroxymethyl-3,4,4-trimethyl-1,2-dioxetane and 3-[N-(pyridino)carbamoyl]methyl-3,4,4-trimethyl-1,2-dioxetane++ + or enzymatically via the aerobic oxidation of isobutyraldehyde trimethylsilyl enol ether catalyzed by horse-radish peroxidase, triggers the SOS function sfiA in E. coli. Although the observed effects are relatively weak and the triplet ketone scavenger tryptophan was ineffective in this system, our results provide evidence for the involvement of triplet ketones in this type of DNA damage. Possible mechanisms are discussed. Topics: Antioxidants; Bacterial Proteins; DNA Damage; DNA Repair; Energy Metabolism; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation; Heterocyclic Compounds; Ketones; Oxidation-Reduction; Peroxidases; Silicon; SOS Response, Genetics; Trimethylsilyl Compounds	1988

Article

Year

Induction of the SOS function sfiA in E. coli by systems which generate triplet ketones.

Mutation research, 1988, Volume: 198, Issue:1

Generation of triplet ketones, either chemically through thermal decomposition of 3-hydroxymethyl-3,4,4-trimethyl-1,2-dioxetane and 3-[N-(pyridino)carbamoyl]methyl-3,4,4-trimethyl-1,2-dioxetane++ + or enzymatically via the aerobic oxidation of isobutyraldehyde trimethylsilyl enol ether catalyzed by horse-radish peroxidase, triggers the SOS function sfiA in E. coli. Although the observed effects are relatively weak and the triplet ketone scavenger tryptophan was ineffective in this system, our results provide evidence for the involvement of triplet ketones in this type of DNA damage. Possible mechanisms are discussed.

Topics: Antioxidants; Bacterial Proteins; DNA Damage; DNA Repair; Energy Metabolism; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation; Heterocyclic Compounds; Ketones; Oxidation-Reduction; Peroxidases; Silicon; SOS Response, Genetics; Trimethylsilyl Compounds

1988