sildenafil-citrate and lorazepam-glucuronide

sildenafil-citrate has been researched along with lorazepam-glucuronide* in 1 studies

Other Studies

1 other study(ies) available for sildenafil-citrate and lorazepam-glucuronide

ArticleYear
Identification of lorazepam and sildenafil as examples for the application of LC/ionspray-MS and MS-MS with mass spectra library searching in forensic toxicology.
    Forensic science international, 2000, Sep-11, Volume: 113, Issue:1-3

    A mass spectra (MS) library using in-source collision induced dissociation (ESI-CID) as well as a tandem-mass spectra (MS-MS) library with product ion spectra of drugs has recently been developed with a triple-quadrupole ionspray mass spectrometer [1,2]. For the ESI-CID MS library, single-quadrupole mode and for the MS-MS library triple-quadrupole mode have been used. These mass spectra libraries were applied successfully for the general-unknown screening for drugs and metabolites in serum and urine with liquid-chromatography-mass spectrometry (LC-MS) using a PE/SCIEX API 365 with a turboionspray source. As examples, the identification of lorazepam and lorazepam-glucuronide in a serum extract and the identification of sildenafil and alkyloxidated sildenafil in urine are presented here.

    Topics: Databases, Factual; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Lorazepam; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Spectrometry, Mass, Secondary Ion; Substance Abuse Detection; Sulfones; Toxicology

2000