sildenafil-citrate has been researched along with 2-cyanoacetamide* in 1 studies
1 other study(ies) available for sildenafil-citrate and 2-cyanoacetamide
| Article | Year |
|---|---|
A simplified green chemistry approaches to synthesis of 2-substituted 1,2,3-triazoles and 4-amino-5-cyanopyrazole derivatives conventional heating versus microwave and ultrasound as ecofriendly energy sources.
Cyanoacetamides 3 were prepared via reacting ethyl cyanoacetate with benzylamine. Yields and reaction times needed for reaction completion at room temperature, by microwaves (muomega) heating and under ultrasound (US) irradiations are compared. The formed cyanoacetamides were coupled with aromatic diazonium salts and the formed arylhydrazones were used as precursors to title triazoles and pyrazoles via reacting the former with hydroxylamine and chloroacetonitrile. Yields of products formed via conventional heating are compared with those of muomega and US irradiation. Topics: Green Chemistry Technology; Hot Temperature; Microwaves; Nitriles; Piperazines; Purines; Purinones; Pyrazoles; Sildenafil Citrate; Sulfones; Triazoles; Ultrasonics | 2009 |