silaproline has been researched along with tetrahydrofuran* in 1 studies
1 other study(ies) available for silaproline and tetrahydrofuran
Article | Year |
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Resolution of protected silaproline for a gram scale preparation.
Silaproline is an analogue of proline, which exhibits similar conformational properties. Moreover, the presence of dimethylsilyl group confers to silaproline a higher lipophilicity as well as an improved resistance to biodegradation. This report describes the comparison of two routes to obtain Fmoc-(L) Sip-OH on the gram scale using chiral HPLC resolution. Topics: Amino Acids; Chromatography, High Pressure Liquid; Fluorenes; Furans; Glycine; Molecular Structure; Organosilicon Compounds; Proline; Solvents; Stereoisomerism | 2012 |