Page last updated: 2024-08-16

sibutramine and leptin

sibutramine has been researched along with leptin in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (5.26)	18.2507
2000's	25 (65.79)	29.6817
2010's	11 (28.95)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Borrell, L; Foreyt, JP; Haddock, CK; Poston, WS	1
Bray, GA; Galasso, GJ; Rössner, S; Ryan, DH	1
Birkeland, KI; Tonstad, S	1
Leiter, L; Shear, NH; Trakas, K	1
Dunn-Meynell, AA; Levin, BE	1
Dei Cas, A; Magnati, G	1
Astrup, A	1
Blackburn, GL; Fernstrom, MH	1
Bing, C; Brown, M; Heal, D; King, P; Pickavance, L; Wilding, J	1
Aronne, LJ; Boozer, CN; Cha, MC; Leibel, RL; Love, RJ	1
DeShields, S; Elashoff, R; Go, VL; Heber, D; Hershman, JM; Liu, Y; Wang, HJ; Yip, I	1
Anarat, R; Gokcel, A; Gumurdulu, Y; Karademir, BM; Karakose, H	1
Boguszewski, CL; De Almeida, SM; Niclewicz, PA; Radominski, RB; Rodrigues, AM; Suplicy, Hde L	1
Gura, T	1
Astrup, A; Feldt-Rasmussen, U; Klose, M; Mersebach, H; Svendsen, OL	1
Akdemir, O; Arslan, M; Karabacak, IY; Karabacak, O; Törüner, FB	1
Chen, HL; Lei, MX; Wu, J	1
Faria, AN; Gouvea Ferreira, SR; Kohlmann, NE; Ribeiro Filho, FF; Zanella, MT	1
McLoughlin, C	1
Baranowska, B; Baranowska-Bik, A; Boguradzka, A; Chmielowska, M; Martyńska, L; Mazurczak-Pluta, T; Wolińska-Witort, E	1
Choi, S; Fernstrom, JD	1
Al-Zaman, Y; Aylwin, S	1
Böhme, P; Quilliot, D; Zannad, F; Ziegler, O	1
Aronne, LJ; Neff, LM	1
Fukami, T; Gomori, A; Ishihara, A; Ito, J; Iwaasa, H; Kanatani, A; Kitazawa, H; MacNeil, DJ; Mashiko, S; Matsushita, H; Mitobe, Y; Moriya, R; Takahashi, T; Van der Ploeg, LH	1
Dontas, I; Galanopoulou, P; Katsilambros, N; Liapi, C; Perelas, A; Perrea, D; Stroubini, T; Trapali, M	1
Faludi, G; Halmy, L; Purebl, G; Rihmer, Z	1
Akbas, H; Coban, E; Eray, E; Ozdem, S; Sari, R	1
Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Gravina, A; Maffioli, P; Mereu, R; Palumbo, I; Randazzo, S; Salvadeo, SA	1
Fosgerau, K; Hansen, G; Hansen, HS; Knudsen, LB; Larsen, PJ; Levin, BE; Lykkegaard, K; Madsen, AN; Paulsen, SJ; Tang-Christensen, M; Vrang, N	1
Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Maffioli, P; Palumbo, I; Randazzo, S	1
Choi, DK; Choi, JW; Joo, JI; Kim, DH; Oh, TS; Wang, X; Yun, JW	1
Abo-Elmatty, DM; Zaitone, SA	1
Bedros, JR; Medvegy, M; Pados, G; Simonyi, G	1
Hainerová, IA; Lebl, J	1
Baretić, M	1
Cominato, L; Damiani, D; Franco, RR	1
De Vincentis, A; Derosa, G; Maffioli, P; Pedone, C; Picardi, A; Sahebkar, A; Vespasiani-Gentilucci, U	1

Reviews

13 review(s) available for sibutramine and leptin

Article	Year
Challenges in obesity management. Southern medical journal, 1998, Volume: 91, Issue:8 Topics: 1-Naphthylamine; Adrenergic beta-Agonists; Appetite Depressants; Behavior Therapy; Caffeine; Cyclobutanes; Diethylpropion; Ephedrine; Fenfluramine; Fluoxetine; Humans; Lactones; Leptin; Lipase; Obesity; Orlistat; Phentermine; Proteins; Sertraline	1998
[The obesity epidemics--do diet pills have a place in the treatment?]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2000, Jun-30, Volume: 120, Issue:17 Topics: Anti-Obesity Agents; Appetite Depressants; Cyclobutanes; Fenfluramine; Humans; Lactones; Leptin; Obesity; Obesity, Morbid; Orlistat; Phentermine; Selective Serotonin Reuptake Inhibitors; Weight Loss	2000
Does drug therapy of obesity have a future? The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique, 2000,Autumn, Volume: 7, Issue:3 Topics: Animals; Appetite Depressants; Cyclobutanes; Humans; Leptin; Mice; Mice, Obese; Obesity; Weight Loss	2000
Thermogenic drugs as a strategy for treatment of obesity. Endocrine, 2000, Volume: 13, Issue:2 Topics: Adrenal Glands; Anti-Obesity Agents; Caffeine; Cyclobutanes; Energy Metabolism; Ephedrine; Humans; Leptin; Obesity; Recombinant Proteins; Sympathetic Nervous System; Thermogenesis	2000
Pharmacological treatments for obesity. Professional nurse (London, England), 2005, Volume: 20, Issue:8 Topics: Anti-Obesity Agents; Appetite Depressants; Cyclobutanes; Humans; Lactones; Leptin; Obesity; Orlistat	2005
The development of tolerance to drugs that suppress food intake. Pharmacology & therapeutics, 2008, Volume: 117, Issue:1 Topics: Animals; Appetite Depressants; Body Weight; Cyclobutanes; Drug Tolerance; Eating; Fenfluramine; Humans; Leptin; Obesity; Rats; Time Factors; Weight Loss	2008
Emerging concepts in the medical and surgical treatment of obesity. Frontiers of hormone research, 2008, Volume: 36 Topics: Adipose Tissue; Amyloid; Anticonvulsants; Antidepressive Agents; Anxiety; Appetite Regulation; Bariatric Surgery; Body Mass Index; Bupropion; Cholecystokinin; Ciliary Neurotrophic Factor; Clinical Trials as Topic; Cyclobutanes; Depression; Diabetes Mellitus, Type 2; Female; Fluoxetine; Fructose; Ghrelin; Humans; Intra-Abdominal Fat; Islet Amyloid Polypeptide; Isoxazoles; Lactones; Leptin; Metabolic Syndrome; Metformin; Obesity; Obesity, Morbid; Orlistat; Oxyntomodulin; Peptide YY; Piperidines; Polycystic Ovary Syndrome; Pyrazoles; Rimonabant; Sertraline; Sleep Apnea, Obstructive; Surgical Procedures, Operative; Topiramate; Zonisamide	2008
Pharmacotherapy for obesity. Current atherosclerosis reports, 2007, Volume: 9, Issue:6 Topics: Amyloid; Anti-Obesity Agents; Appetite Depressants; Body Weight; Chronic Disease; Comorbidity; Cyclobutanes; Exenatide; Gastrointestinal Hormones; Humans; Islet Amyloid Polypeptide; Lactones; Leptin; Metformin; Obesity; Orlistat; Peptides; Piperidines; Pyrazoles; Randomized Controlled Trials as Topic; Rimonabant; Venoms	2007
[Association of obesity and depression]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2008, Volume: 10, Issue:4 Topics: Anti-Obesity Agents; Antidepressive Agents; Appetite Depressants; Appetite Regulation; Bipolar Disorder; Circadian Rhythm; Cyclobutanes; Depression; Depressive Disorder, Major; Dietary Carbohydrates; Energy Intake; Ghrelin; Humans; Hypothalamo-Hypophyseal System; Insulin Resistance; Leptin; Obesity; Piperidines; Pituitary-Adrenal System; Pyrazoles; Rimonabant; Seasonal Affective Disorder; Sleep Wake Disorders; Surveys and Questionnaires; Weight Gain; Weight Loss	2008
[The pharmacological treatment of obesity: past, present and future]. Orvosi hetilap, 2012, Mar-11, Volume: 153, Issue:10 Topics: Amides; Anti-Obesity Agents; Anticonvulsants; Antidepressive Agents; Basal Metabolism; Benzazepines; Benzoxazines; Body Mass Index; Bridged Bicyclo Compounds, Heterocyclic; Ciliary Neurotrophic Factor; Clinical Trials as Topic; Combined Modality Therapy; Cyclobutanes; Dexfenfluramine; Fatty Acids; Female; Fenfluramine; Glucagon-Like Peptide 1; Human Growth Hormone; Humans; Intestinal Absorption; Lactones; Leptin; Life Style; Liraglutide; Male; Norepinephrine; Obesity; Obesity, Morbid; Orlistat; Piperidines; Pyrazoles; Pyridines; Receptor, Melanocortin, Type 4; Rimonabant; Satiation; Serotonin; Sodium-Glucose Transport Proteins; Sucrose; Thyroid Hormones	2012
Treatment options for children with monogenic forms of obesity. World review of nutrition and dietetics, 2013, Volume: 106 Topics: Bariatric Surgery; Body Mass Index; Body Weight; Child; Cyclobutanes; Energy Metabolism; Heterozygote; Homozygote; Humans; Leptin; Mutation; Obesity; Pro-Opiomelanocortin; Receptor, Melanocortin, Type 4; Weight Loss	2013
Obesity drug therapy. Minerva endocrinologica, 2013, Volume: 38, Issue:3 Topics: Anti-Obesity Agents; Appetite; Combined Modality Therapy; Comorbidity; Cost-Benefit Analysis; Cyclobutanes; Diabetes Mellitus, Type 2; Diet, Diabetic; Drug Combinations; Exercise Therapy; Fructose; Gastrointestinal Hormones; Humans; Incretins; Insulin; Insulin Secretion; Intestines; Lactones; Leptin; Life Style; Models, Biological; Neuropeptides; Obesity; Orlistat; Phentermine; Phytotherapy; Piperidines; Plant Preparations; Pyrazoles; Rimonabant; Topiramate	2013
Effect of Sibutramine on Plasma C-Reactive Protein, Leptin and Adipon ectin Concentrations: A Systematic Review and Meta-Analysis of Randomized Contr olled Trials. Current pharmaceutical design, 2017, Volume: 23, Issue:6 Topics: Adiponectin; Anti-Obesity Agents; Body Mass Index; Body Weight; C-Reactive Protein; Cyclobutanes; Humans; Leptin; Randomized Controlled Trials as Topic	2017

Trials

12 trial(s) available for sibutramine and leptin

Article	Year
Insulin-leptin-visceral fat relation during weight loss. Pancreas, 2001, Volume: 23, Issue:2 Topics: Adipose Tissue; Adult; Appetite Depressants; Cyclobutanes; Diet, Reducing; Female; Humans; Insulin; Leptin; Male; Middle Aged; Obesity; Time Factors; Viscera; Weight Loss	2001
Effects of sibutramine in non-dieting obese women. Journal of endocrinological investigation, 2002, Volume: 25, Issue:2 Topics: Adult; Appetite Depressants; Blood Glucose; Body Mass Index; C-Peptide; Cyclobutanes; Female; Glucose Tolerance Test; Homeostasis; Humans; Insulin; Insulin Resistance; Leptin; Liver; Obesity; Placebos	2002
The cerebrospinal fluid/serum leptin ratio during pharmacological therapy for obesity. The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:4 Topics: Adolescent; Adult; Amphetamines; Anti-Obesity Agents; Appetite Depressants; Cyclobutanes; Humans; Lactones; Leptin; Middle Aged; Obesity; Orlistat; Weight Loss	2002
Treatment effect of sibutramine compared to fluoxetine on leptin levels in polycystic ovary disease. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2004, Volume: 19, Issue:4 Topics: Adult; Appetite Depressants; Body Mass Index; Cyclobutanes; Female; Fluoxetine; Follicle Stimulating Hormone; Glucose Tolerance Test; Humans; Leptin; Luteinizing Hormone; Polycystic Ovary Syndrome; Selective Serotonin Reuptake Inhibitors	2004
[Serum leptin and insulin resistance in obesity and effects of sibutramine on them]. Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 2003, Volume: 28, Issue:6 Topics: Adolescent; Adult; Appetite Depressants; Body Mass Index; Cyclobutanes; Double-Blind Method; Female; Humans; Insulin Resistance; Leptin; Linear Models; Male; Middle Aged; Obesity	2003
Effects of sibutramine on abdominal fat mass, insulin resistance and blood pressure in obese hypertensive patients. Diabetes, obesity & metabolism, 2005, Volume: 7, Issue:3 Topics: Adult; Antihypertensive Agents; Appetite Depressants; Chi-Square Distribution; Cyclobutanes; Drug Therapy, Combination; Female; Glucose Tolerance Test; Humans; Hypertension; Insulin Resistance; Leptin; Lipids; Male; Middle Aged; Obesity; Waist-Hip Ratio; Weight Loss	2005
Sibutramine therapy in obese women--effects on plasma neuropeptide Y (NPY), insulin, leptin and beta-endorphin concentrations. Neuro endocrinology letters, 2005, Volume: 26, Issue:6 Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Analysis of Variance; Appetite Depressants; Appetite Regulation; beta-Endorphin; Cyclobutanes; Female; Humans; Insulin; Leptin; Neuropeptide Y; Obesity; Reference Values; Selective Serotonin Reuptake Inhibitors; Statistics, Nonparametric	2005
Sympathetic-leptin relationship in obesity: effect of weight loss. Metabolism: clinical and experimental, 2008, Volume: 57, Issue:4 Topics: Adult; Appetite Depressants; Blood Pressure; Body Composition; Cyclobutanes; Female; Heart Rate; Humans; Leptin; Middle Aged; Obesity; Regression Analysis; Sympathetic Nervous System; Weight Loss	2008
Comparison of the effects of sibutramine versus sibutramine plus metformin in obese women. Clinical and experimental medicine, 2010, Volume: 10, Issue:3 Topics: Adult; Appetite Depressants; C-Reactive Protein; Cyclobutanes; Drug Therapy, Combination; Female; Humans; Insulin Resistance; Leptin; Metformin; Middle Aged; Obesity; Treatment Outcome; Weight Loss	2010
Effects of combination of sibutramine and L-carnitine compared with sibutramine monotherapy on inflammatory parameters in diabetic patients. Metabolism: clinical and experimental, 2011, Volume: 60, Issue:3 Topics: Aged; Appetite Depressants; Blood Glucose; Body Weight; C-Reactive Protein; Carnitine; Cholesterol; Cyclobutanes; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Insulin Resistance; Leptin; Longitudinal Studies; Male; Middle Aged; Tumor Necrosis Factor-alpha; Vitamin B Complex	2011
Variation of inflammatory parameters after sibutramine treatment compared to placebo in type 2 diabetic patients. Journal of clinical pharmacy and therapeutics, 2011, Volume: 36, Issue:5 Topics: Adiponectin; Appetite Depressants; Blood Glucose; Body Mass Index; Body Weight; C-Reactive Protein; Comorbidity; Cyclobutanes; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Inflammation; Insulin; Insulin Resistance; Leptin; Lipids; Male; Middle Aged; Obesity; Placebos; Randomized Controlled Trials as Topic; Thiazolidinediones; Time Factors	2011
[The effect of sibutramine on weight loss in obese adolescents]. Arquivos brasileiros de endocrinologia e metabologia, 2014, Volume: 58, Issue:3 Topics: Adolescent; Appetite Depressants; Blood Glucose; Body Mass Index; Child; Cholesterol; Cross-Over Studies; Cyclobutanes; Double-Blind Method; Female; Humans; Insulin; Leptin; Male; Patient Safety; Pediatric Obesity; Treatment Outcome; Triglycerides; Weight Loss	2014

Other Studies

13 other study(ies) available for sibutramine and leptin

Article	Year
Conference report--obesity: new directions, June 27-29, 1998, Charleston, South Carolina. Obesity research, 1999, Volume: 7, Issue:3 Topics: Appetite Depressants; Behavior Therapy; Cyclobutanes; Diet, Reducing; Disease Outbreaks; Female; Global Health; Humans; Leptin; Norepinephrine; Obesity; Prevalence; Proteins	1999
Sibutramine alters the central mechanisms regulating the defended body weight in diet-induced obese rats. American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:6 Topics: Adipose Tissue; Animals; Appetite Depressants; Arcuate Nucleus of Hypothalamus; Body Weight; Cyclobutanes; Energy Intake; Epinephrine; Feeding Behavior; Gene Expression Regulation; Homeostasis; Leptin; Neuropeptide Y; Norepinephrine; Obesity; Organ Size; Pro-Opiomelanocortin; Rats; RNA, Messenger	2000
Energy homeostasis and body weight in obesity: new physiopathological and therapeutic considerations. Eating and weight disorders : EWD, 2000, Volume: 5, Issue:3 Topics: Appetite Depressants; Body Weight; Brain; Cyclobutanes; Energy Intake; Homeostasis; Humans; Leptin; Obesity	2000
Toward optimal health: the experts discuss weight control drugs. Interview by Jodi Godfrey Meisler. Journal of women's health & gender-based medicine, 2001, Volume: 10, Issue:2 Topics: Anti-Obesity Agents; Appetite Depressants; Body Mass Index; Counseling; Cyclobutanes; Diet, Reducing; Drug Therapy, Combination; Exercise; Female; Humans; Lactones; Leptin; Life Style; Obesity; Orlistat; Patient Education as Topic; Patient Selection; Primary Health Care; United States; Weight Loss; Women's Health	2001
Sibutramine reduces feeding, body fat and improves insulin resistance in dietary-obese male Wistar rats independently of hypothalamic neuropeptide Y. British journal of pharmacology, 2001, Volume: 132, Issue:8 Topics: Adipose Tissue; Animals; Appetite Depressants; Body Weight; Cyclobutanes; Diet; Feeding Behavior; Hypothalamus; Insulin Resistance; Leptin; Male; Neurons; Neuropeptide Y; Obesity; Rats; Rats, Wistar; RNA, Messenger	2001
Synergy of sibutramine and low-dose leptin in treatment of diet-induced obesity in rats. Metabolism: clinical and experimental, 2001, Volume: 50, Issue:8 Topics: Animals; Body Composition; Body Weight; Cyclobutanes; Diet; Drug Synergism; Energy Intake; Energy Metabolism; Feeding Behavior; Leptin; Male; Obesity; Rats; Rats, Sprague-Dawley	2001
Obesity drug pipeline not so fat. Science (New York, N.Y.), 2003, Feb-07, Volume: 299, Issue:5608 Topics: Agouti-Related Protein; alpha-MSH; Animals; Anti-Obesity Agents; Appetite; Arcuate Nucleus of Hypothalamus; Ciliary Neurotrophic Factor; Clinical Trials as Topic; Cyclobutanes; Energy Intake; Ghrelin; Humans; Hunger; Intercellular Signaling Peptides and Proteins; Lactones; Leptin; Mice; Nerve Tissue Proteins; Neurons; Neuropeptide Y; Obesity; Orlistat; Peptide Fragments; Peptide Hormones; Peptide YY; Phentermine; Proteins; Receptors, Corticotropin; Receptors, Melanocortin; Weight Loss	2003
Combined dietary and pharmacological weight management in obese hypopituitary patients. Obesity research, 2004, Volume: 12, Issue:11 Topics: Adult; Anthropometry; Appetite Depressants; Blood Glucose; Body Composition; Cholesterol; Combined Modality Therapy; Cyclobutanes; Exercise; Female; Human Growth Hormone; Humans; Hypopituitarism; Leptin; Lipids; Male; Middle Aged; Obesity; Pregnancy; Weight Loss	2004
Effects of a novel Y5 antagonist in obese mice: combination with food restriction or sibutramine. Obesity (Silver Spring, Md.), 2008, Volume: 16, Issue:7 Topics: Adiposity; Animals; Anti-Obesity Agents; Appetite Depressants; Blood Glucose; Body Weight; Caloric Restriction; Combined Modality Therapy; Cyclobutanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Eating; Insulin; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Receptors, Neuropeptide Y; Spiro Compounds; Spironolactone; Time Factors	2008
Effect of sibutramine on regional fat pads and leptin levels in rats fed with three isocaloric diets. European cytokine network, 2008, Volume: 19, Issue:3 Topics: Adipose Tissue; Animals; Appetite Depressants; Cyclobutanes; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Eating; Leptin; Lipid Metabolism; Male; Rats; Rats, Wistar; Time Factors	2008
Long-term characterization of the diet-induced obese and diet-resistant rat model: a polygenetic rat model mimicking the human obesity syndrome. The Journal of endocrinology, 2010, Volume: 206, Issue:3 Topics: Analysis of Variance; Animals; Appetite Depressants; Blood Glucose; Cyclobutanes; Diet; Disease Models, Animal; Eating; Enzyme-Linked Immunosorbent Assay; Feeding Behavior; Glucagon-Like Peptide 1; Insulin; Insulin Resistance; Leptin; Liraglutide; Metabolic Syndrome; Obesity; Rats; Rats, Sprague-Dawley	2010
Proteome changes in rat plasma in response to sibutramine. Proteomics, 2011, Volume: 11, Issue:7 Topics: Adipose Tissue; Animals; Appetite Depressants; Appetite Regulation; Blood Proteins; Body Weight; Cardiovascular Diseases; Chromatography, Liquid; Cyclobutanes; Electrophoresis, Gel, Two-Dimensional; Insulin; Leptin; Male; Obesity; Proteome; Rats; Rats, Sprague-Dawley; Risk Factors; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Weight Loss	2011
Topiramate induces weight loss and improves insulin sensitivity in dietary obese rats: comparison to sibutramine. European review for medical and pharmacological sciences, 2011, Volume: 15, Issue:10 Topics: Animals; Anti-Obesity Agents; Blood Glucose; Blood Pressure; Cyclobutanes; Female; Fructose; Insulin; Insulin Resistance; Leptin; Lipids; Obesity; Rats; Topiramate; Weight Loss	2011