Page last updated: 2024-08-16

sibutramine and fenfluramine

sibutramine has been researched along with fenfluramine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (34.78)18.2507
2000's8 (34.78)29.6817
2010's7 (30.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lean, ME1
Abdeen, MA; Frishman, WH; Michaelson, MD; Weiser, M1
Heal, DJ; Hutchins, LJ; Jackson, HC; Mazurkiewicz, SE; Needham, AM1
Auerbach, SB; Gundlah, C; Heal, DJ; Martin, KF1
Borrell, L; Foreyt, JP; Haddock, CK; Poston, WS1
Aspley, S; Cheetham, SC; Heal, DJ; Jackson, HC; Martin, KF; Prow, MR1
Birkeland, KI; Tonstad, S1
Ryan, DH1
Bickerdike, MJ; Dourish, CT; Vickers, SP1
Dill, PL; Ericsson, M; Foreyt, JP; Haddock, CK; Poston, WS1
Jones, SL; Miller, DK; Wellman, PJ1
Cheng, D; Chi, CL; Gan, J; Han, S; Largent, BL; O'Tanyi, EJ; Rohrbach, KW; Taub, R; Zhang, H1
Chan, AY; Lai, CK; Mak, TW; Ng, SW; Poon, WT; Yuen, YP1
Choi, S; Fernstrom, JD1
Bernardi, G; Federici, M; Ledonne, A; Mercuri, NB; Sebastianelli, L1
Kaplan, LM1
Astrup, A1
Gao, B; Shi, Y; Sun, A; Sun, C1
Fujioka, M; Mikami, E; Miyamoto, K; Sumioka, S; Yamamoto, S1
Bedros, JR; Medvegy, M; Pados, G; Simonyi, G1
Chen, B; Ding, L; Guo, B; Sun, W; Wang, H; Wu, Y; Zhao, Y1
Guo, L; Jin, R; Li, L; Li, W; Shen, Q1

Reviews

11 review(s) available for sibutramine and fenfluramine

ArticleYear
Sibutramine--a review of clinical efficacy.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1997, Volume: 21 Suppl 1

    Topics: Anti-Obesity Agents; Antidepressive Agents; Appetite Depressants; Body Weight; Cardiovascular Physiological Phenomena; Cardiovascular System; Clinical Trials as Topic; Cyclobutanes; Dose-Response Relationship, Drug; Fenfluramine; Humans; Obesity; Weight Loss

1997
The pharmacologic approach to the treatment of obesity.
    Journal of clinical pharmacology, 1997, Volume: 37, Issue:6

    Topics: Adrenergic beta-Agonists; Appetite Depressants; Cardiovascular Diseases; Cyclobutanes; Energy Metabolism; Fenfluramine; Fluoxetine; Humans; Obesity

1997
Challenges in obesity management.
    Southern medical journal, 1998, Volume: 91, Issue:8

    Topics: 1-Naphthylamine; Adrenergic beta-Agonists; Appetite Depressants; Behavior Therapy; Caffeine; Cyclobutanes; Diethylpropion; Ephedrine; Fenfluramine; Fluoxetine; Humans; Lactones; Leptin; Lipase; Obesity; Orlistat; Phentermine; Proteins; Sertraline

1998
Sibutramine: a novel anti-obesity drug. A review of the pharmacological evidence to differentiate it from d-amphetamine and d-fenfluramine.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1998, Volume: 22 Suppl 1

    Topics: Animals; Biogenic Monoamines; Cyclobutanes; Dextroamphetamine; Energy Metabolism; Fenfluramine; Humans; Hypertension, Pulmonary; Obesity; Selective Serotonin Reuptake Inhibitors

1998
[The obesity epidemics--do diet pills have a place in the treatment?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2000, Jun-30, Volume: 120, Issue:17

    Topics: Anti-Obesity Agents; Appetite Depressants; Cyclobutanes; Fenfluramine; Humans; Lactones; Leptin; Obesity; Obesity, Morbid; Orlistat; Phentermine; Selective Serotonin Reuptake Inhibitors; Weight Loss

2000
Use of sibutramine and other noradrenergic and serotonergic drugs in the management of obesity.
    Endocrine, 2000, Volume: 13, Issue:2

    Topics: Adrenergic Agents; Appetite Depressants; Cyclobutanes; Dexfenfluramine; Dextroamphetamine; Fenfluramine; Heart Valve Diseases; Humans; Obesity; Phenylpropanolamine; Serotonin Agents; Weight Loss

2000
5-HT2C receptor modulation and the treatment of obesity.
    Diabetes, obesity & metabolism, 1999, Volume: 1, Issue:4

    Topics: Animals; Appetite Depressants; Cyclobutanes; Disease Models, Animal; Fenfluramine; Humans; Obesity; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors

1999
Pharmacotherapy for obesity: a quantitative analysis of four decades of published randomized clinical trials.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2002, Volume: 26, Issue:2

    Topics: Amphetamines; Anti-Obesity Agents; Benzphetamine; Cyclobutanes; Fenfluramine; Humans; Obesity; Randomized Controlled Trials as Topic

2002
The development of tolerance to drugs that suppress food intake.
    Pharmacology & therapeutics, 2008, Volume: 117, Issue:1

    Topics: Animals; Appetite Depressants; Body Weight; Cyclobutanes; Drug Tolerance; Eating; Fenfluramine; Humans; Leptin; Obesity; Rats; Time Factors; Weight Loss

2008
Pharmacologic therapies for obesity.
    Gastroenterology clinics of North America, 2010, Volume: 39, Issue:1

    Topics: Anti-Obesity Agents; Appetite Depressants; Bariatric Surgery; Benzazepines; Bupropion; Cyclobutanes; Ephedrine; Fenfluramine; Humans; Lactones; Naltrexone; Obesity; Orlistat; Phentermine; Weight Gain; Weight Loss

2010
[The pharmacological treatment of obesity: past, present and future].
    Orvosi hetilap, 2012, Mar-11, Volume: 153, Issue:10

    Topics: Amides; Anti-Obesity Agents; Anticonvulsants; Antidepressive Agents; Basal Metabolism; Benzazepines; Benzoxazines; Body Mass Index; Bridged Bicyclo Compounds, Heterocyclic; Ciliary Neurotrophic Factor; Clinical Trials as Topic; Combined Modality Therapy; Cyclobutanes; Dexfenfluramine; Fatty Acids; Female; Fenfluramine; Glucagon-Like Peptide 1; Human Growth Hormone; Humans; Intestinal Absorption; Lactones; Leptin; Life Style; Liraglutide; Male; Norepinephrine; Obesity; Obesity, Morbid; Orlistat; Piperidines; Pyrazoles; Pyridines; Receptor, Melanocortin, Type 4; Rimonabant; Satiation; Serotonin; Sodium-Glucose Transport Proteins; Sucrose; Thyroid Hormones

2012

Other Studies

12 other study(ies) available for sibutramine and fenfluramine

ArticleYear
Comparison of the effects of sibutramine and other monoamine reuptake inhibitors on food intake in the rat.
    British journal of pharmacology, 1997, Volume: 121, Issue:8

    Topics: Animals; Cyclobutanes; Cyclohexanols; Eating; Fenfluramine; Fluoxetine; Male; Neurotransmitter Uptake Inhibitors; Obesity; Rats; Rats, Sprague-Dawley; Venlafaxine Hydrochloride

1997
In vivo criteria to differentiate monoamine reuptake inhibitors from releasing agents: sibutramine is a reuptake inhibitor.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cyclobutanes; Fenfluramine; Fluoxetine; Male; Microdialysis; Paroxetine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin

1997
Studies confirm link between fen-phen and heart-valve disease.
    Harvard heart letter : from Harvard Medical School, 1998, Volume: 9, Issue:4

    Topics: Appetite Depressants; Cyclobutanes; Dexfenfluramine; Drug Combinations; Fenfluramine; Heart Valve Diseases; Humans; Obesity; Phentermine

1998
Effects of preexposure to dexfenfluramine, phentermine, dexfenfluramine-phentermine, or fluoxetine on sibutramine-induced hypophagia in the adult rat.
    Pharmacology, biochemistry, and behavior, 2003, Volume: 75, Issue:1

    Topics: Animals; Antidepressive Agents, Second-Generation; Appetite Depressants; Body Weight; Cyclobutanes; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Eating; Fenfluramine; Fluoxetine; Male; Norepinephrine; Phentermine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors

2003
Disconnection between the early onset anorectic effects by C75 and hypothalamic fatty acid synthase inhibition in rodents.
    European journal of pharmacology, 2005, Mar-21, Volume: 511, Issue:1

    Topics: 4-Butyrolactone; Animals; Appetite Depressants; Behavior, Animal; Blotting, Northern; Cyclobutanes; Dose-Response Relationship, Drug; Fatty Acid Synthases; Fenfluramine; Food Deprivation; Hypothalamus; Immunoblotting; Injections, Intraperitoneal; Injections, Intraventricular; Kinetics; Male; Phentermine; Random Allocation; Rats; Rats, Inbred F344; RNA; Time Factors

2005
Adulteration of over-the-counter slimming products with pharmaceutical analogue--an emerging threat.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2007, Volume: 13, Issue:3

    Topics: Adult; Anti-Obesity Agents; Appetite Depressants; Chemistry, Pharmaceutical; Cyclobutanes; Drug and Narcotic Control; Drug Contamination; Female; Fenfluramine; Hong Kong; Hospitalization; Humans; Liver; Male; Middle Aged; Nonprescription Drugs; Selective Serotonin Reuptake Inhibitors; Thyroid Hormones; Toxicity Tests; Weight Loss

2007
The anorexic agents, sibutramine and fenfluramine, depress GABA(B)-induced inhibitory postsynaptic potentials in rat mesencephalic dopaminergic cells.
    British journal of pharmacology, 2009, Volume: 156, Issue:6

    Topics: Animals; Appetite Depressants; Baclofen; Cyclobutanes; Dopamine; Fenfluramine; GABA-A Receptor Agonists; GABA-B Receptor Agonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Mesencephalon; Neurons; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, GABA-A; Receptors, GABA-B; Serotonin 5-HT1 Receptor Agonists; Substantia Nigra; Ventral Tegmental Area

2009
Drug management of obesity--efficacy versus safety.
    The New England journal of medicine, 2010, Jul-15, Volume: 363, Issue:3

    Topics: Anti-Obesity Agents; Benzazepines; Contraindications; Cyclobutanes; Drug Approval; Fenfluramine; Humans; Obesity; Overweight; Serotonin 5-HT2 Receptor Agonists; Serotonin Receptor Agonists; United States; United States Food and Drug Administration; Weight Loss

2010
Development of a liquid chromatography tandem mass spectrometry method for simultaneous determination of eight adulterants in slimming functional foods.
    Journal of chromatography. A, 2011, Oct-21, Volume: 1218, Issue:42

    Topics: Anthraquinones; Chromatography, Liquid; Clopamide; Cyclobutanes; Diet, Reducing; Emodin; Ephedrine; Fenfluramine; Food Contamination; Functional Food; Linear Models; Methanol; Phenylpropanolamine; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Temperature

2011
Study on detection of drugs in slimming health foods using GC-MS/MS.
    Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 2011, Volume: 52, Issue:6

    Topics: Cyclobutanes; Drug Approval; Fenfluramine; Food, Organic; Gas Chromatography-Mass Spectrometry; Legislation, Drug; Mazindol; Phenolphthalein; Tandem Mass Spectrometry

2011
Rapid screening of illicit additives in weight loss dietary supplements with desorption corona beam ionisation (DCBI) mass spectrometry.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2012, Volume: 29, Issue:8

    Topics: Anti-Obesity Agents; Appetite Depressants; China; Chromatography, High Pressure Liquid; Cyclobutanes; Dietary Supplements; Fenfluramine; Food Contamination; Food Inspection; Indicators and Reagents; Legislation, Food; Mass Spectrometry; Phenolphthalein; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors

2012
A graphene tip coupled with liquid chromatography tandem mass spectrometry for the determination of four synthetic adulterants in slimming supplements.
    Food chemistry, 2017, Jun-01, Volume: 224

    Topics: Appetite Depressants; Bumetanide; Chromatography, Liquid; Cyclobutanes; Dietary Supplements; Fenfluramine; Graphite; Limit of Detection; Phenolphthalein; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry

2017