Page last updated: 2024-08-16

sibutramine and dexfenfluramine

sibutramine has been researched along with dexfenfluramine in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (22.22)18.2507
2000's10 (55.56)29.6817
2010's4 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Drouin, P; Hanotin, C; Jones, SP; Leutenegger, E; Thomas, F1
Rissanen, A1
De Leeuw, IH; Van Gaal, LF; Wauters, MA1
Kalia, M; Kramer, M; Miller, DB; O'Callaghan, JP1
Aronne, LJ; Hirsch, J; Mackintosh, RM1
Cheetham, SC; Heal, DJ; Slater, NA; Viggers, JA1
Ballmer, PE; Imoberdorf, R1
Ryan, DH1
Czupryniak, L; Drzewoski, J1
Bénardeau, A; Künnecke, B; Verry, P; von Kienlin, M1
Alemany, M; Cabot, C; Fernández-López, JA; Ferrer-Lorente, R; Remesar, X1
Foltin, RW1
Brune, ME; Bush, EN; Droz, BA; Fey, T; Jacobson, PB; Knourek-Segel, VE; Lin, E; Shapiro, R1
Bedros, JR; Medvegy, M; Pados, G; Simonyi, G1
Arumugam, S; Devan, SRK; Poosala, S; Shankar, G1

Reviews

5 review(s) available for sibutramine and dexfenfluramine

ArticleYear
Pharmacological intervention: the antiobesity approach.
    European journal of clinical investigation, 1998, Volume: 28 Suppl 2

    Topics: Appetite Depressants; Blood Glucose; Controlled Clinical Trials as Topic; Cyclobutanes; Dexfenfluramine; Diabetes Mellitus, Type 2; Humans; Lactones; Longitudinal Studies; Obesity; Orlistat; Weight Loss

1998
Anti-obesity drugs: what does sibutramine offer? An analysis of its potential contribution to obesity treatment.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 1998, Volume: 106 Suppl 2

    Topics: Adipose Tissue; Appetite Depressants; Blood Glucose; Blood Pressure; Cyclobutanes; Dexfenfluramine; Dose-Response Relationship, Drug; Energy Intake; Energy Metabolism; Humans; Lipids; Obesity; Weight Loss

1998
[Obesity: principles of drug therapy].
    Therapeutische Umschau. Revue therapeutique, 2000, Volume: 57, Issue:8

    Topics: Aminorex; Anti-Obesity Agents; Appetite Depressants; Chronic Disease; Combined Modality Therapy; Cyclobutanes; Dexfenfluramine; Diet, Reducing; Drug and Narcotic Control; Germany; Heart Valve Diseases; Humans; Hypertension, Pulmonary; Lactones; Obesity; Orlistat; Phentermine

2000
Use of sibutramine and other noradrenergic and serotonergic drugs in the management of obesity.
    Endocrine, 2000, Volume: 13, Issue:2

    Topics: Adrenergic Agents; Appetite Depressants; Cyclobutanes; Dexfenfluramine; Dextroamphetamine; Fenfluramine; Heart Valve Diseases; Humans; Obesity; Phenylpropanolamine; Serotonin Agents; Weight Loss

2000
[The pharmacological treatment of obesity: past, present and future].
    Orvosi hetilap, 2012, Mar-11, Volume: 153, Issue:10

    Topics: Amides; Anti-Obesity Agents; Anticonvulsants; Antidepressive Agents; Basal Metabolism; Benzazepines; Benzoxazines; Body Mass Index; Bridged Bicyclo Compounds, Heterocyclic; Ciliary Neurotrophic Factor; Clinical Trials as Topic; Combined Modality Therapy; Cyclobutanes; Dexfenfluramine; Fatty Acids; Female; Fenfluramine; Glucagon-Like Peptide 1; Human Growth Hormone; Humans; Intestinal Absorption; Lactones; Leptin; Life Style; Liraglutide; Male; Norepinephrine; Obesity; Obesity, Morbid; Orlistat; Piperidines; Pyrazoles; Pyridines; Receptor, Melanocortin, Type 4; Rimonabant; Satiation; Serotonin; Sodium-Glucose Transport Proteins; Sucrose; Thyroid Hormones

2012

Trials

2 trial(s) available for sibutramine and dexfenfluramine

ArticleYear
A comparison of sibutramine and dexfenfluramine in the treatment of obesity.
    Obesity research, 1998, Volume: 6, Issue:4

    Topics: Adult; Appetite Depressants; Body Constitution; Body Mass Index; Body Weight; Cyclobutanes; Dexfenfluramine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Obesity; Serotonin Receptor Agonists; Treatment Outcome

1998
The effects of drugs used to treat obesity on the autonomic nervous system.
    Obesity research, 2000, Volume: 8, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Appetite Depressants; Atropine; Autonomic Nervous System; Basal Metabolism; Calorimetry; Creatinine; Cyclobutanes; Dexfenfluramine; Dopamine; Epinephrine; Heart Rate; Humans; Male; Norepinephrine; Obesity; Parasympatholytics; Phentermine; Propanolamines; Serotonin Receptor Agonists; Single-Blind Method

2000

Other Studies

11 other study(ies) available for sibutramine and dexfenfluramine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Studies confirm link between fen-phen and heart-valve disease.
    Harvard heart letter : from Harvard Medical School, 1998, Volume: 9, Issue:4

    Topics: Appetite Depressants; Cyclobutanes; Dexfenfluramine; Drug Combinations; Fenfluramine; Heart Valve Diseases; Humans; Obesity; Phentermine

1998
Comparative study of fluoxetine, sibutramine, sertraline and dexfenfluramine on the morphology of serotonergic nerve terminals using serotonin immunohistochemistry.
    Brain research, 2000, Mar-06, Volume: 858, Issue:1

    Topics: Animals; Appetite Depressants; Body Weight; Cyclobutanes; Dexfenfluramine; Eating; Fluoxetine; Immunohistochemistry; Male; N-Methyl-3,4-methylenedioxyamphetamine; Prefrontal Cortex; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Sertraline

2000
Sibutramine does not decrease the number of 5-HT re-uptake sites in rat brain and, like fluoxetine, protects against the deficits produced by dexfenfluramine.
    Neuropharmacology, 2000, Aug-23, Volume: 39, Issue:11

    Topics: Animals; Appetite Depressants; Brain; Cyclobutanes; Dexfenfluramine; Fluoxetine; Male; Paroxetine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists

2000
[The role of pharmacotherapy for treatment of obesity in adults].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2000, Volume: 9, Issue:53

    Topics: Adult; Animals; Anti-Obesity Agents; Chlorphentermine; Cyclobutanes; Dexfenfluramine; Dopamine Agonists; Ephedrine; Fluoxetine; Humans; Lactones; Mazindol; Obesity; Orlistat

2000
Quantitative body composition analysis in awake mice and rats by magnetic resonance relaxometry.
    Obesity research, 2004, Volume: 12, Issue:10

    Topics: Animals; Anti-Obesity Agents; Body Composition; Calibration; Cross-Sectional Studies; Cyclobutanes; Dexfenfluramine; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred AKR; Mice, Inbred C57BL; Mice, Obese; Obesity; Rats; Rats, Sprague-Dawley; Rats, Wistar; Rats, Zucker; Reproducibility of Results; Sensitivity and Specificity; Weight Loss

2004
Effects of oleoyl-estrone with dexfenfluramine, sibutramine or phentermine on overweight rats.
    European journal of pharmacology, 2005, Apr-25, Volume: 513, Issue:3

    Topics: Animals; Anti-Obesity Agents; Body Weight; Cyclobutanes; Dexfenfluramine; Drug Interactions; Drug Therapy, Combination; Energy Metabolism; Estrone; Insulin; Lipids; Male; Obesity; Oleic Acids; Phentermine; Rats; Rats, Wistar

2005
Effects of sibutramine on the appetitive and consummatory aspects of feeding in non-human primates.
    Physiology & behavior, 2006, Feb-28, Volume: 87, Issue:2

    Topics: Animals; Appetite Depressants; Conditioning, Operant; Consummatory Behavior; Cyclobutanes; Data Interpretation, Statistical; Dexfenfluramine; Dose-Response Relationship, Drug; Eating; Food; Male; Papio; Reinforcement Schedule; Sex Characteristics

2006
Chronic treatment with either dexfenfluramine or sibutramine in diet-switched diet-induced obese mice.
    Endocrine, 2006, Volume: 29, Issue:2

    Topics: Animals; Anti-Obesity Agents; Body Weight; Cyclobutanes; Dexfenfluramine; Diet, Fat-Restricted; Ghrelin; Growth Hormone; Male; Mice; Obesity; Peptide Hormones; Thinness; Weight Gain

2006
Differential sensitivity of chronic high-fat-diet-induced obesity in Sprague-Dawley rats.
    Journal of basic and clinical physiology and pharmacology, 2018, 09-25, Volume: 29, Issue:5

    Topics: Animals; Cyclobutanes; Dexfenfluramine; Diet, High-Fat; Eating; Male; Obesity; Oxygen Consumption; Rats; Rats, Sprague-Dawley

2018