shikimic acid has been researched along with flavin mononucleotide in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bornemann, S; Lowe, DJ; Macheroux, P; Petersen, J; Thorneley, RN | 1 |
| Bornemann, S; Ghisla, S; Macheroux, P; Thorneley, RN | 1 |
| Bornemann, S; Koch, MH; Macheroux, P; Schönbrunn, E; Svergun, DI; Thorneley, RN; Volkov, VV | 1 |
| Abell, C; Bornemann, S; Osborne, A; Thorneley, RN | 1 |
| Amrhein, N; Kitzing, K; Macheroux, P | 1 |
| Ahn, HJ; Lee, B; Suh, SW; Yoon, HJ | 1 |
| Ehammer, H; Kappes, B; Macheroux, P; Prem, A; Rauch, G | 1 |
| Bornemann, S; Ehammer, H; Macheroux, P; Rauch, G | 1 |
| Arcuri, HA; Palma, MS | 1 |
| Dhindwal, S; Kumar, A; Kumar, P; Tapas, S | 1 |
| Khera, HK; Singh, S; Singh, SK | 1 |
| Qureshi, IA; Singh, S | 1 |
1 review(s) available for shikimic acid and flavin mononucleotide
| Article | Year |
|---|---|
Understanding the structure, activity and inhibition of chorismate synthase from Mycobacterium tuberculosis.
Topics: Enzyme Inhibitors; Flavin Mononucleotide; Mycobacterium tuberculosis; Phosphorus-Oxygen Lyases; Protein Structure, Tertiary; Shikimic Acid | 2011 |
11 other study(ies) available for shikimic acid and flavin mononucleotide
| Article | Year |
|---|---|
Binding of the oxidized, reduced, and radical flavin species to chorismate synthase. An investigation by spectrophotometry, fluorimetry, and electron paramagnetic resonance and electron nuclear double resonance spectroscopy.
Topics: Electron Spin Resonance Spectroscopy; Flavin Mononucleotide; Fluorometry; Free Radicals; Light; Lyases; Magnetic Resonance Spectroscopy; Organophosphorus Compounds; Oxidation-Reduction; Phosphorus-Oxygen Lyases; Shikimic Acid | 1996 |
Studies with flavin analogs provide evidence that a protonated reduced FMN is the substrate-induced transient intermediate in the reaction of Escherichia coli chorismate synthase.
Topics: Enzyme Inhibitors; Escherichia coli; Flavin Mononucleotide; Lyases; Organophosphorus Compounds; Phosphorus-Oxygen Lyases; Shikimic Acid; Spectrophotometry, Ultraviolet; Stereoisomerism | 1996 |
Evidence for a major structural change in Escherichia coli chorismate synthase induced by flavin and substrate binding.
Topics: Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Flavin Mononucleotide; Kinetics; Models, Molecular; Oxidation-Reduction; Phosphorus-Oxygen Lyases; Protein Conformation; Protein Denaturation; Scattering, Radiation; Shikimic Acid; Solubility; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Trypsin; Tryptophan; Ultraviolet Rays | 1998 |
Studies with substrate and cofactor analogues provide evidence for a radical mechanism in the chorismate synthase reaction.
Topics: Benzoquinones; Chromatography, High Pressure Liquid; Dithionite; Escherichia coli; Flavin Mononucleotide; Inhibitory Concentration 50; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Organophosphorus Compounds; Oxidation-Reduction; Phosphorus-Oxygen Lyases; Recombinant Proteins; Shikimic Acid; Spectrophotometry | 2000 |
Spectroscopic and kinetic characterization of the bifunctional chorismate synthase from Neurospora crassa: evidence for a common binding site for 5-enolpyruvylshikimate 3-phosphate and NADPH.
Topics: Binding Sites; Cloning, Molecular; DNA, Complementary; Escherichia coli; Flavin Mononucleotide; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; NADP; Neurospora crassa; Oxidoreductases; Oxygen; Phosphorus-Oxygen Lyases; Plasmids; Protein Binding; Protein Structure, Tertiary; Shikimic Acid; Spectrometry, Fluorescence; Spectrophotometry; Substrate Specificity; Time Factors; Ultraviolet Rays | 2001 |
Crystal structure of chorismate synthase: a novel FMN-binding protein fold and functional insights.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Carrier Proteins; Crystallography, X-Ray; Flavin Mononucleotide; Flavoproteins; Helicobacter pylori; Models, Molecular; Molecular Sequence Data; Phosphorus-Oxygen Lyases; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Quaternary; Protein Subunits; Sequence Alignment; Shikimic Acid | 2004 |
Conservation of NADPH utilization by chorismate synthase and its implications for the evolution of the shikimate pathway.
Topics: Bacterial Proteins; Evolution, Molecular; Flavin Mononucleotide; Fungal Proteins; Isoenzymes; NADP; Phenotype; Phosphorus-Oxygen Lyases; Saccharomyces cerevisiae; Shikimic Acid | 2007 |
Replacement of two invariant serine residues in chorismate synthase provides evidence that a proton relay system is essential for intermediate formation and catalytic activity.
Topics: Alanine; Amino Acid Substitution; Catalysis; Flavin Mononucleotide; Flavins; Histidine; Hydrogen Bonding; Mutagenesis, Site-Directed; Neurospora crassa; Phosphorus-Oxygen Lyases; Protein Binding; Protons; Serine; Shikimic Acid; Substrate Specificity | 2008 |
Structural analysis of chorismate synthase from Plasmodium falciparum: a novel target for antimalaria drug discovery.
Topics: Amino Acid Sequence; Antimalarials; Catalytic Domain; Drug Discovery; Enzyme Inhibitors; Flavin Mononucleotide; Helicobacter pylori; Models, Molecular; Molecular Sequence Data; Molecular Targeted Therapy; Phosphorus-Oxygen Lyases; Phylogeny; Plasmodium falciparum; Protein Multimerization; Protein Structure, Secondary; Sequence Alignment; Shikimic Acid; Thermodynamics | 2011 |
Chorismate synthase from malaria parasites is bifunctional enzyme.
Topics: Flavin Mononucleotide; Malaria; Phosphorus-Oxygen Lyases; Plasmodium falciparum; Plasmodium vivax; Recombinant Proteins; Shikimic Acid | 2019 |
Identification of potent inhibitors against chorismate synthase of Toxoplasma gondii using molecular dynamics simulations.
Topics: Benzofurans; Flavin Mononucleotide; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Phosphorus-Oxygen Lyases; Shikimic Acid; Toxoplasma; Toxoplasmosis | 2022 |