shikimic acid-3-phosphate and shikimic acid

shikimic acid-3-phosphate has been researched along with shikimic acid in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19909 (20.93)18.7374
1990's13 (30.23)18.2507
2000's14 (32.56)29.6817
2010's7 (16.28)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gruys, KJ; Sikorski, JA; Walker, MC1
Frazier, RB; Ream, JE; Sikorski, JA; Yuen, HK1
Huynh, QK2
Anderson, KS; Johnson, KA1
Bauer, SC; Bild, GS; Borgmeyer, JR; Huynh, QK; Kishore, GM1
Anderson, KS; Johnson, KA; Sikorski, JA1
Berry, A; Fischer, RS; Gaines, CG; Jensen, RA1
Bild, GS; Huynh, QK; Kishore, GM1
Aykent, S; Huynh, QK; Kishore, GM; Padgette, SR; Sammons, RD; Sikorski, JA1
Sharps, ES1
Ahmad, S; Arora, N; Bhatnagar, RK; Fattah, FA; Majumder, K; Selvapandiyan, A1
Merabet, EK; Sikorski, JA; Walker, MC; Yuen, HK1
Christensen, AM; Schaefer, J1
Cohen, ER; McDowell, LM; Schaefer, J; Schmidt, A; Studelska, DR1
Kim, DH; Lees, WJ; Tucker-Kellogg, GW; Walsh, CT1
Gruys, KJ; Marzabadi, MR; Pansegrau, PD; Sikorski, JA; Walker, MC; Yuen, HK1
Ahmad, S; Arora, N; Bhatnagar, RK; Majumder, K; Selvapandiyan, A1
Espe, MP; Klug, CA; McDowell, LM; Schaefer, J; Studelska, DR1
Evans, JN; Jakeman, DL; Mitchell, DJ; Shuttleworth, WA1
Chalker, AF; Du, W; Kallender, H; Liu, WS; Mazzulla, MJ; Payne, DJ; Wallis, NG; Zhang, L1
Doyle, ML; Du, W; Liu, WS; Payne, DJ1
Alibhai, MF; Stallings, WC1
Evans, JN; Stauffer, ME; Young, JK1
Evans, JN; Helms, GL; Stauffer, ME; Young, JK1
Boocock, MR; Coggins, JR1
Eschenburg, S; Healy, ML; Lushington, GH; Priestman, MA; Schönbrunn, E1
LEVIN, JG; SPRINSON, DB1
An, M; Bartlett, PA; Maitra, U; Neidlein, U1
Basso, LA; Canduri, F; da Silveira, NJ; de Azevedo, WF; de Oliveira, JS; Palma, MS; Pereira, JH; Santos, DS1
Beusen, DD; McDowell, LM; O'Connor, RD; Poliks, B; Schaefer, J; Studelska, DR1
Evans, JN; Hilsenbeck, JL; Kang, C; Kim, HJ; Park, H; Park, YH; Shuttleworth, WA1
Bartunik, HD; Bourenkov, GP; Hartmann, MD; Oberschall, A; Strizhov, N1
Kang, SH; Kim, HJ; Kim, HW1
Berti, PJ; Chindemi, P1
Chen, M; Han, Y; Jiang, Y; Li, L; Lin, M; Lu, W; Ping, S; Yan, Y; Zhang, W; Zhao, Z1
Caetano, MS; da Cunha, EF; Freitas, MP; Ramalho, TC1
Basso, LA; Frappier, V; Najmanovich, RJ; Palma, MS; Rosado, LA; Santos, DS; Vasconcelos, IB1
Cao, Y; Feng, S; Qiao, D; Xie, L; Xu, H; Yi, Y; Yu, Y1
Calderón, AI; Gill, G; Goodwin, DC; Simithy, J; Wang, Y1
Anderson, WF; Krishna, SN; Light, SH; Minasov, G1
Breen, J; Russo, TA; Schultz, LW; Sutton, KA; Umland, TC1
Brundiek, H; Meier, R; Obkircher, M; Schoenenberger, B; Wohlgemuth, R; Wszolek, A1

Reviews

1 review(s) available for shikimic acid-3-phosphate and shikimic acid

ArticleYear
Closing down on glyphosate inhibition--with a new structure for drug discovery.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Mar-13, Volume: 98, Issue:6

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Animals; Enzyme Inhibitors; Glycine; Glyphosate; Protein Structure, Tertiary; Shikimic Acid

2001

Other Studies

42 other study(ies) available for shikimic acid-3-phosphate and shikimic acid

ArticleYear
Substrate synergism and the steady-state kinetic reaction mechanism for EPSP synthase from Escherichia coli.
    Biochemistry, 1992, Jun-23, Volume: 31, Issue:24

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Escherichia coli; Glycine; Glyphosate; Kinetics; Magnetic Resonance Spectroscopy; Phosphoenolpyruvate; Shikimic Acid; Transferases

1992
EPSP synthase: binding studies using isothermal titration microcalorimetry and equilibrium dialysis and their implications for ligand recognition and kinetic mechanism.
    Biochemistry, 1992, Jun-23, Volume: 31, Issue:24

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Calorimetry; Escherichia coli; Glycine; Glyphosate; In Vitro Techniques; Kinetics; Ligands; Phosphates; Phosphoenolpyruvate; Shikimic Acid; Thermodynamics; Transferases

1992
5-Enolpyruvylshikimate-3-phosphate synthase from Escherichia coli--the substrate analogue bromopyruvate inactivates the enzyme by modifying Cys-408 and Lys-411.
    Archives of biochemistry and biophysics, 1991, Feb-01, Volume: 284, Issue:2

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Amino Acid Sequence; Cysteine; Enzyme Activation; Escherichia coli; Hydrolysis; Kinetics; Ligands; Lysine; Molecular Sequence Data; Pyruvates; Shikimic Acid; Substrate Specificity; Transferases; Trypsin

1991
"Kinetic competence" of the 5-enolpyruvoylshikimate-3-phosphate synthase tetrahedral intermediate.
    The Journal of biological chemistry, 1990, Apr-05, Volume: 265, Issue:10

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Binding Sites; Drug Stability; Escherichia coli; Half-Life; Hydrogen-Ion Concentration; Kinetics; Molecular Structure; Phosphates; Phosphoenolpyruvate; Protein Binding; Shikimic Acid; Thermodynamics; Transferases

1990
Evidence for a reactive gamma-carboxyl group (Glu-418) at the herbicide glyphosate binding site of 5-enolpyruvylshikimate-3-phosphate synthase from Escherichia coli.
    The Journal of biological chemistry, 1988, Aug-25, Volume: 263, Issue:24

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Amino Acid Sequence; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Enzyme Activation; Escherichia coli; Ethyldimethylaminopropyl Carbodiimide; Glutamates; Glutamic Acid; Glycine; Glyphosate; Herbicides; Kinetics; Molecular Sequence Data; Shikimic Acid; Transferases

1988
Site-directed mutagenesis of Petunia hybrida 5-enolpyruvylshikimate-3-phosphate synthase: Lys-23 is essential for substrate binding.
    The Journal of biological chemistry, 1988, Aug-25, Volume: 263, Issue:24

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alanine; Alkyl and Aryl Transferases; Arginine; Binding Sites; Binding, Competitive; Glutamates; Glutamic Acid; Glycine; Glyphosate; Herbicides; Lysine; Mutation; Phosphoenolpyruvate; Plants; Pyridoxal Phosphate; Shikimic Acid; Transferases

1988
A tetrahedral intermediate in the EPSP synthase reaction observed by rapid quench kinetics.
    Biochemistry, 1988, Sep-20, Volume: 27, Issue:19

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Escherichia coli; Kinetics; Molecular Structure; Phosphates; Phosphoenolpyruvate; Shikimic Acid; Transferases

1988
Comparative action of glyphosate as a trigger of energy drain in eubacteria.
    Journal of bacteriology, 1986, Volume: 168, Issue:3

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Amino Acids; Bacillus subtilis; Bacterial Proteins; Energy Metabolism; Escherichia coli; Glycine; Glyphosate; Pseudomonas aeruginosa; Shikimic Acid; Species Specificity; Transferases

1986
5-Enolpyruvyl shikimate 3-phosphate synthase from Escherichia coli. Identification of Lys-22 as a potential active site residue.
    The Journal of biological chemistry, 1988, Jan-15, Volume: 263, Issue:2

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Amino Acid Sequence; Binding Sites; Chromatography, High Pressure Liquid; Escherichia coli; Kinetics; Lysine; Peptide Fragments; Phosphoenolpyruvate; Shikimic Acid; Transferases; Trypsin

1988
Identification of the reactive cysteines of Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase and their nonessentiality for enzymatic catalysis.
    The Journal of biological chemistry, 1988, Feb-05, Volume: 263, Issue:4

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Binding Sites; Cysteine; Dithionitrobenzoic Acid; Escherichia coli; Glycine; Glyphosate; Kinetics; Shikimic Acid; Transferases

1988
A radiometric assay for 5-enolpyruvylshikimate-3-phosphate synthase.
    Analytical biochemistry, 1984, Volume: 140, Issue:1

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Carbon Radioisotopes; Chromatography, Paper; Enterobacter; Hydrogen-Ion Concentration; Isotope Labeling; Shikimic Acid; Transferases

1984
Point mutation of a conserved arginine (104) to lysine introduces hypersensitivity to inhibition by glyphosate in the 5-enolpyruvylshikimate-3-phosphate synthase of Bacillus subtilis.
    FEBS letters, 1995, Oct-30, Volume: 374, Issue:2

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Amino Acid Sequence; Arginine; Bacillus subtilis; Binding Sites; Conserved Sequence; Enzyme Inhibitors; Glutamine; Glycine; Glyphosate; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphoenolpyruvate; Point Mutation; Shikimic Acid; Substrate Specificity; Transferases

1995
Differential scanning calorimetric study of 5-enolpyruvoyl shikimate-3-phosphate synthase and its complexes with shikimate-3-phosphate and glyphosate: irreversible thermal transitions.
    Biochimica et biophysica acta, 1993, Feb-13, Volume: 1161, Issue:2-3

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Calorimetry, Differential Scanning; Enzyme Stability; Escherichia coli; Hydrogen-Ion Concentration; Models, Theoretical; Protein Denaturation; Shikimic Acid; Thermodynamics; Transferases

1993
Solid-state NMR determination of intra- and intermolecular 31P-13C distances for shikimate 3-phosphate and [1-13C]glyphosate bound to enolpyruvylshikimate-3-phosphate synthase.
    Biochemistry, 1993, Mar-23, Volume: 32, Issue:11

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Binding Sites; Carbon Isotopes; Escherichia coli; Glycine; Glyphosate; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Phosphorus; Protein Conformation; Shikimic Acid; Transferases

1993
Structural constraints on the ternary complex of 5-enolpyruvylshikimate-3-phosphate synthase from rotational-echo double-resonance NMR.
    Journal of molecular biology, 1996, Feb-16, Volume: 256, Issue:1

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Arginine; Binding Sites; Escherichia coli; Glycine; Glyphosate; Histidine; Lysine; Magnetic Resonance Spectroscopy; Molecular Structure; Nitrogen Isotopes; Shikimic Acid; Transferases

1996
Analysis of fluoromethyl group chirality establishes a common stereochemical course for the enolpyruvyl transfers catalyzed by EPSP synthase and UDP-GlcNAc enolpyruvyl transferase.
    Biochemistry, 1996, Apr-30, Volume: 35, Issue:17

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Base Sequence; DNA Primers; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Phosphoenolpyruvate; Recombinant Proteins; Shikimic Acid; Stereoisomerism; Transferases

1996
An EPSP synthase inhibitor joining shikimate 3-phosphate with glyphosate: synthesis and ligand binding studies.
    Biochemistry, 1996, Apr-02, Volume: 35, Issue:13

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Binding Sites; Calorimetry; Drug Design; Enzyme Inhibitors; Escherichia coli; Glycine; Glyphosate; Herbicides; Indicators and Reagents; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Molecular Structure; Organophosphorus Compounds; Recombinant Proteins; Shikimic Acid; Transferases

1996
Evidence for the shikimate-3-phosphate interacting site in the N-terminal domain of 5-enolpyruvyl shikimate-3-phosphate synthase of Bacillus subtilis.
    Biochemistry and molecular biology international, 1996, Volume: 40, Issue:3

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Bacillus subtilis; Binding Sites; Conserved Sequence; Escherichia coli; Mutagenesis, Site-Directed; Protein Conformation; Protein Folding; Quaternary Ammonium Compounds; Recombinant Proteins; Sequence Homology, Amino Acid; Shikimic Acid; Transferases

1996
Slowed enzymatic turnover allows characterization of intermediates by solid-state NMR.
    Biochemistry, 1997, Dec-16, Volume: 36, Issue:50

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Carbon Isotopes; Escherichia coli; Freeze Drying; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Mutagenesis, Site-Directed; Mutation; Phosphoenolpyruvate; Phosphorus Isotopes; Protein Binding; Shikimic Acid; Temperature

1997
Effects of sample preparation conditions on biomolecular solid-state NMR lineshapes.
    Journal of biomolecular NMR, 1998, Volume: 12, Issue:3

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Bacterial Proteins; Freezing; Glycine; Glyphosate; Macromolecular Substances; Magnetic Resonance Spectroscopy; Polyethylene Glycols; Shikimic Acid; Specimen Handling; Trehalose

1998
Characterization of Streptococcus pneumoniae 5-enolpyruvylshikimate 3-phosphate synthase and its activation by univalent cations.
    European journal of biochemistry, 2000, Volume: 267, Issue:1

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Amino Acid Sequence; Catalysis; Cations; Conserved Sequence; Enzyme Activation; Escherichia coli; Glycine; Glyphosate; Kinetics; L-Lactate Dehydrogenase; Molecular Sequence Data; Molecular Weight; Osmolar Concentration; Phosphoenolpyruvate; Potassium; Pyruvate Kinase; Quaternary Ammonium Compounds; Recombinant Proteins; Sequence Alignment; Shikimic Acid; Streptococcus pneumoniae

2000
Synergistic inhibitor binding to Streptococcus pneumoniae 5-enolpyruvylshikimate-3-phosphate synthase with both monovalent cations and substrate.
    Biochemistry, 2000, Aug-22, Volume: 39, Issue:33

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Calorimetry; Cations, Monovalent; Circular Dichroism; Drug Synergism; Enzyme Inhibitors; Glycine; Glyphosate; Models, Chemical; Protein Conformation; Shikimic Acid; Streptococcus pneumoniae; Ultracentrifugation

2000
Shikimate-3-phosphate binds to the isolated N-terminal domain of 5-enolpyruvylshikimate-3-phosphate synthase.
    Biochemistry, 2001, Apr-03, Volume: 40, Issue:13

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Binding Sites; Calorimetry; Klebsiella pneumoniae; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phosphorus Isotopes; Protein Structure, Secondary; Protein Structure, Tertiary; Shikimic Acid; Substrate Specificity

2001
Chemical shift mapping of shikimate-3-phosphate binding to the isolated N-terminal domain of 5-enolpyruvylshikimate-3-phosphate synthase.
    FEBS letters, 2001, Jun-15, Volume: 499, Issue:1-2

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Amino Acid Sequence; Binding Sites; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Shikimic Acid

2001
Kinetics of 5-enolpyruvylshikimate-3-phosphate synthase inhibition by glyphosate.
    FEBS letters, 1983, Apr-05, Volume: 154, Issue:1

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Glycine; Glyphosate; Kinetics; Neurospora crassa; Shikimic Acid

1983
How the mutation glycine96 to alanine confers glyphosate insensitivity to 5-enolpyruvyl shikimate-3-phosphate synthase from Escherichia coli.
    Planta, 2002, Volume: 216, Issue:1

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alanine; Alkyl and Aryl Transferases; Amino Acid Substitution; Binding Sites; Drug Resistance, Bacterial; Escherichia coli; Glycine; Glyphosate; Kinetics; Klebsiella pneumoniae; Models, Molecular; Mutation; Phosphoenolpyruvate; Shikimic Acid

2002
The formation of 3-enolpyruvyl shikimate 5-phosphate in extracts of Escherichia coli.
    Biochemical and biophysical research communications, 1960, Volume: 3

    Topics: Escherichia coli; Phosphates; Shikimic Acid

1960
5-enolpyruvylshikimate 3-phosphate synthase: chemical synthesis of the tetrahedral intermediate and assignment of the stereochemical course of the enzymatic reaction.
    Journal of the American Chemical Society, 2003, Oct-22, Volume: 125, Issue:42

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Binding Sites; Models, Molecular; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Shikimic Acid; Stereoisomerism

2003
Structural bioinformatics study of EPSP synthase from Mycobacterium tuberculosis.
    Biochemical and biophysical research communications, 2003, Dec-19, Volume: 312, Issue:3

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Amino Acid Sequence; Binding Sites; Computer Simulation; Conserved Sequence; Escherichia coli; Glycine; Glyphosate; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Mycobacterium tuberculosis; Protein Binding; Protein Conformation; Protein Structure, Secondary; Sequence Alignment; Sequence Analysis, Protein; Shikimic Acid; Structure-Activity Relationship

2003
Rotational-echo double-resonance NMR-restrained model of the ternary complex of 5-enolpyruvylshikimate-3-phosphate synthase.
    Journal of biomolecular NMR, 2004, Volume: 28, Issue:1

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Amino Acids, Aromatic; Glycine; Glyphosate; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Structure, Quaternary; Shikimic Acid

2004
Structural studies of Streptococcus pneumoniae EPSP synthase in unliganded state, tetrahedral intermediate-bound state and S3P-GLP-bound state.
    Molecular microbiology, 2004, Volume: 51, Issue:4

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Amino Acid Motifs; Crystallography, X-Ray; Glycine; Glyphosate; Ligands; Models, Molecular; Molecular Weight; Phosphoenolpyruvate; Protein Conformation; Protein Structure, Quaternary; Protein Structure, Tertiary; Shikimic Acid; Streptococcus pneumoniae

2004
Mechanism of phosphoryl transfer catalyzed by shikimate kinase from Mycobacterium tuberculosis.
    Journal of molecular biology, 2006, Dec-01, Volume: 364, Issue:3

    Topics: Adenosine Diphosphate; Bacterial Proteins; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Models, Molecular; Mycobacterium tuberculosis; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Protein Structure, Tertiary; Shikimic Acid; Substrate Specificity

2006
Engineering and characterization of the isolated C-terminal domain of 5-enolpyruvylshikimate-3-phosphate (EPSP) synthase.
    Journal of microbiology and biotechnology, 2007, Volume: 17, Issue:8

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Calorimetry; Circular Dichroism; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Nitrogen Isotopes; Phosphoenolpyruvate; Phosphorus Isotopes; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Shikimic Acid

2007
Catalytic residues and an electrostatic sandwich that promote enolpyruvyl shikimate 3-phosphate synthase (AroA) catalysis.
    Biochemistry, 2009, May-05, Volume: 48, Issue:17

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Aspartic Acid; Catalysis; Catalytic Domain; Cations; Crystallography, X-Ray; Enzyme Stability; Escherichia coli Proteins; Glutamates; Kinetics; Lysine; Shikimic Acid; Static Electricity; Streptococcus pneumoniae; Substrate Specificity

2009
A novel RPMXR motif among class II 5-enolpyruvylshikimate-3-phosphate synthases is required for enzymatic activity and glyphosate resistance.
    Journal of biotechnology, 2009, Volume: 144, Issue:4

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Amino Acid Motifs; Amino Acid Sequence; Conserved Sequence; Drug Resistance, Bacterial; Enzyme Inhibitors; Escherichia coli; Glycine; Glyphosate; Models, Molecular; Mutagenesis, Site-Directed; Phosphoenolpyruvate; Shikimic Acid; Structure-Activity Relationship

2009
Construction and assessment of reaction models of Class I EPSP synthase. Part II: investigation of the EPSP ketal.
    Journal of biomolecular structure & dynamics, 2013, Volume: 31, Issue:4

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Biocatalysis; Catalytic Domain; Glycine; Glyphosate; Hydrogen Bonding; Kinetics; Models, Chemical; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Shikimic Acid; Thermodynamics

2013
The mode of action of recombinant Mycobacterium tuberculosis shikimate kinase: kinetics and thermodynamics analyses.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adenosine Triphosphate; Bacterial Proteins; Calorimetry; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Kinetics; Mycobacterium tuberculosis; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Recombinant Proteins; Shikimic Acid; Thermodynamics; Titrimetry

2013
Fluorimetric analysis of the binding characteristics of 5-enolpyruvylshikimate-3-phosphate synthase with substrates in Dunaliella salina.
    Journal of basic microbiology, 2014, Volume: 54, Issue:9

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Cloning, Molecular; Fluorometry; Gene Expression; Glycine; Glyphosate; Models, Molecular; Phosphoenolpyruvate; Protein Binding; Protein Conformation; Recombinant Proteins; Shikimic Acid; Volvocida

2014
Development of an ESI-LC-MS-based assay for kinetic evaluation of Mycobacterium tuberculosis shikimate kinase activity and inhibition.
    Analytical chemistry, 2015, Feb-17, Volume: 87, Issue:4

    Topics: Antitubercular Agents; Chromatography, Liquid; Enzyme Assays; Humans; Mycobacterium tuberculosis; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase Inhibitors; Shikimic Acid; Spectrometry, Mass, Electrospray Ionization; Tuberculosis

2015
An Unusual Cation-Binding Site and Distinct Domain-Domain Interactions Distinguish Class II Enolpyruvylshikimate-3-phosphate Synthases.
    Biochemistry, 2016, Mar-01, Volume: 55, Issue:8

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Binding Sites; Cations, Monovalent; Coxiella burnetii; Crystallography, X-Ray; Models, Molecular; Phylogeny; Potassium; Protein Conformation; Protein Interaction Domains and Motifs; Shikimic Acid

2016
Crystal structure of 5-enolpyruvylshikimate-3-phosphate (EPSP) synthase from the ESKAPE pathogen Acinetobacter baumannii.
    Acta crystallographica. Section F, Structural biology communications, 2016, Volume: 72, Issue:Pt 3

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Acinetobacter baumannii; Amino Acid Sequence; Bacterial Proteins; Catalytic Domain; Crystallization; Crystallography, X-Ray; Models, Molecular; Protein Conformation, alpha-Helical; Shikimic Acid

2016
Recombinant AroL-Catalyzed Phosphorylation for the Efficient Synthesis of Shikimic Acid 3-Phosphate.
    Biotechnology journal, 2018, Volume: 13, Issue:8

    Topics: Enzyme Stability; Escherichia coli; Escherichia coli Proteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Recombinant Proteins; Shikimic Acid

2018