Page last updated: 2024-08-24

setoperone and pyrimidinones

setoperone has been researched along with pyrimidinones in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (21.43)	18.7374
1990's	23 (41.07)	18.2507
2000's	15 (26.79)	29.6817
2010's	6 (10.71)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Blin, J; Crouzel, C	1
Baron, JC; Bletry, O; Blin, J; Crouzel, C; Elghozi, JL; Fiorelli, M; Sette, G	1
Cohen, ML; Kurz, KD; Schenck, KW	1
Gelders, YG	1
Gerber, R; Gerhardt, SC; Liebman, JM	1
Matsubara, S; Meltzer, HY	1
Buzzi, MG; Falaschi, P; Lestingi, L; Marini, S; Meco, G; Pasqualoni, V; Petrini, P	1
Gudelsky, GA; Meltzer, HY; Nash, JF	1
Gommeren, W; Laduron, PM; Leysen, JE; van Gompel, P	1
Gommeren, W; Janssen, PA; Leysen, JE; Van Gompel, P; Woestenborghs, R	1
Bisserbe, JC; Crouzel, C; Maziere, B; Ottaviani, M; Pascal, O; Sanz, G; Sejourne, C; Stulzaft, O; Venet, M	1
Baron, JC; Blin, J; Crouzel, C; Kiyosawa, M; Pappata, S	1
de Chaffoy de Courcelles, D; Leysen, JE; Niemegeers, CJ; Van Gompel, P	1
Ceulemans, DL; Gelders, YG; Hoppenbrouwers, ML; Janssen, PA; Reyntjens, AJ	1
Boullais, N; Bousser, MG; Chabriat, H; Pappata, S; Samson, Y; Tehindrazanarivelo, A; Vera, P	1
Matsubara, R	1
Agid, Y; Attar-Lévy, D; Baron, JC; Blin, J; Crouzel, C; Dubois, B; Fiorelli, M; Fournier, D; Pillon, B; Vidailhet, M	1
Baron, JC; Barré, L; Landeau, B; Osmont, A; Petit-Taboué, MC; Tillet, I	1
Alpert, NM; Babich, JW; Bonab, AA; Elmaleh, DR; Fischman, AJ; Rauch, SL; Rubin, RH; Shoup, TM; Williams, SA	1
Amarenco, G; Amarenco, P; Bousser, MG; Chabriat, H; Kerdraon, J; Ménard, JF; Rancurel, G; Samson, Y; Véra, P; Zilbovicius, M	1
DaSilva, JD; Houle, S; Jones, C; Kapur, S; Wilson, AA; Zipursky, RB	1
DaSilva, J; Houle, S; Jones, C; Kapur, S; Wilson, A	1
Attar-Levy, D; Beaufils, B; Corruble, E; Feline, A; Martinot, JL; Massou, JM; Trichard, C	1
Houle, S; Jones, C; Kapur, S; McKay, G; Remington, G; Zipursky, R	1
Attar-Levy, D; Martinot, JL; Monnet, F; Paillère-Martinot, ML; Recassens, C; Trichard, C	1
Attar-Levy, D; Blin, J; Feline, A; Martinot, JL; Paillère-Martinot, ML; Trichard, C	1
DaSilva, J; Houle, S; Jones, C; Kapur, S; Remington, G; Wilson, AA; Zipursky, RB	1
Brown, GM; DaSilva, J; Houle, S; Jones, C; Kapur, S; Lewis, R; Wilson, AA; Zipursky, RB	1
Baron, JC; Barré, L; Landeau, B; Noël, MH; Onfroy, MC; Petit-Taboué, MC	1
Attar-Lévy, D; Aymard, N; Blin, J; Bourdel, MC; Crouzel, C; Dao-Castellana, MH; Féline, A; Martinot, JL; Mazoyer, B; Poirier, MF; Syrota, A	1
Kapur, S; Remington, G; Zipursky, RB	1
Cho, R; Du, L; Hrdina, P; Kapur, S	1
Brown, GM; DaSilva, J; Houle, S; Kapur, S; Kennedy, SH; Meyer, JH; Owczarek, B; Wilson, AA	1
Cho, R; Kapur, S; Kennedy, S; Meyer, JH	1
Adam, MJ; Dennie, J; Lam, RW; Lane, CJ; Liddle, PF; Ruth, TJ; Shiah, IS; Yatham, LN	1
Liddle, PF; Ngan, ET; Ruth, TJ; Yatham, LN	1
Adam, MJ; Lam, RW; Liddle, PF; Ruth, TJ; Scarrow, G; Shiah, IS; Yatham, LN; Zis, AP	1
Coote, M; Lam, RW; Liddle, PF; Shiah, IS; Steiner, M; Yatham, LN; Zis, AP	1
Hussey, D; Kapur, S; Kecojevic, A; Lewis, R; Meyer, JH; Tauscher, J; Verhoeff, NP; Zipursky, RB	1
Brown, GM; DaSilva, J; Eisfeld, B; Houle, S; Kapur, S; Kennedy, SH; Mayberg, HS; Meyer, JH; Rafi-Tari, S; Wilson, AA	1
Adam, MJ; Lam, RW; Liddle, PF; Ruth, TJ; Shiah, IS; Yatham, LN; Zis, AP	1
Blak, T; Brown, GM; DaSilva, JN; Eynan-Harvey, R; Goulding, VS; Houle, S; Kennedy, SH; Korman, L; Links, P; McMain, S; Meyer, JH; Wilson, AA	1
Kapur, S; Mamo, D; Romach, MK; Sedman, E; Sellers, EM; Tillner, J	1
Kapur, S; Mamo, D; Mann, S; Papatheodorou, G; Remington, G; Shammi, CM; Therrien, F	1
Clark, CM; Doudet, DJ; Strome, EM; Zis, AP	1
Ansari, MS; Dawant, B; Jayathilake, K; Kessler, RM; Li, R; Meltzer, HY; Riccardi, P	1
Adam, MJ; Chinnapalli, M; Lam, RW; Liddle, PF; Ruth, TJ; Solomons, K; Yatham, LN	1
Graff, A; Kapur, S; Mamo, D; Mizrahi, R; Romeyer, F; Shammi, CM	1
Anderson, GM; Goldberg, J; Hall, GB; Nahmias, C; Szatmari, P; Thompson, A; Zwaigenbaum, L	1
Chow, TW; Graff-Guerrero, A; Houle, S; Mamo, DC; Mulsant, BH; Pollock, BG; Smith, GS; Uchida, H	1
Gerretsen, P; Graff-Guerrero, A; Houle, S; Kapur, S; Mamo, D; Menon, M; Pollock, BG; Vasdev, N	1
Ballanger, B; Fox, SH; Houle, S; Rusjan, PM; Strafella, AP; van Eimeren, T; Zurowski, M	1
Adam, MJ; Lam, RW; Liddle, PF; Ruth, TJ; Sossi, V; Stoessl, AJ; Yatham, LN; Zis, AP	1
Chow, TW; Graff-Guerrero, A; Houle, S; Kapur, S; Mamo, DC; Mulsant, BH; Pollock, BG; Uchida, H	1
Ansari, MS; Baldwin, RM; Benningfield, M; Blackford, JU; Cao, A; Cowan, RL; Di Iorio, CR; Dietrich, MS; Kessler, RM; Li, R; Rogers, B; Salomon, RM; Watkins, TJ	1
Bauman, ML; Beversdorf, DQ; Bonab, AA; Dougherty, DD; Felopulos, GJ; Fischman, AJ; Nordgren, RE; Weise, SB; Zhou, FC	1

Trials

9 trial(s) available for setoperone and pyrimidinones

Article	Year
Thymosthenic agents, a novel approach in the treatment of schizophrenia. The British journal of psychiatry. Supplement, 1989, Issue:5 Topics: Brain; Butyrophenones; Humans; Isoxazoles; Piperidines; Pyrimidinones; Randomized Controlled Trials as Topic; Receptors, Serotonin; Risperidone; Ritanserin; Schizophrenia; Schizophrenic Psychology; Serotonin Antagonists	1989
5-HT2 and D2 receptor occupancy of olanzapine in schizophrenia: a PET investigation. The American journal of psychiatry, 1998, Volume: 155, Issue:7 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Carbon Radioisotopes; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorine Radioisotopes; Humans; Male; Olanzapine; Pirenzepine; Prolactin; Pyrimidinones; Raclopride; Receptors, Dopamine D2; Receptors, Serotonin; Salicylamides; Schizophrenia; Tomography, Emission-Computed; Treatment Outcome	1998
The cortical serotonin2 receptors studied with positron-emission tomography and [18F]-setoperone during depressive illness and antidepressant treatment with clomipramine. Biological psychiatry, 1999, Jan-15, Volume: 45, Issue:2 Topics: Adult; Aged; Antidepressive Agents; Binding Sites; Brain; Clomipramine; Depressive Disorder; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Pyrimidinones; Receptors, Serotonin; Tomography, Emission-Computed	1999
Relationship between central and peripheral serotonin 5-HT2A receptors: a positron emission tomography study in healthy individuals. Neuroscience letters, 1999, Feb-19, Volume: 261, Issue:3 Topics: Adult; Blood Platelets; Central Nervous System; Female; Humans; Kinetics; Lysergic Acid Diethylamide; Male; Neocortex; Peripheral Nerves; Pyrimidinones; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Tomography, Emission-Computed	1999
Dysfunctional attitudes and 5-HT2 receptors during depression and self-harm. The American journal of psychiatry, 2003, Volume: 160, Issue:1 Topics: Adolescent; Adult; Attitude; Brain Mapping; Cerebral Cortex; Clonidine; Depressive Disorder, Major; Female; Fenfluramine; Humans; Male; Personality Inventory; Pyrimidinones; Receptors, Serotonin; Reference Values; Self-Injurious Behavior; Tomography, Emission-Computed	2003
EMD 281014, a specific and potent 5HT2 antagonist in humans: a dose-finding PET study. Psychopharmacology, 2004, Volume: 175, Issue:3 Topics: Adult; Dose-Response Relationship, Drug; Female; Fluorine Radioisotopes; Frontal Lobe; Humans; Indoles; Male; Middle Aged; Piperazines; Positron-Emission Tomography; Pyrimidinones; Radiopharmaceuticals; Receptors, Serotonin, 5-HT2; Serotonin 5-HT2 Receptor Antagonists	2004
A PET study of dopamine D2 and serotonin 5-HT2 receptor occupancy in patients with schizophrenia treated with therapeutic doses of ziprasidone. The American journal of psychiatry, 2004, Volume: 161, Issue:5 Topics: Adult; Antipsychotic Agents; Brain; Corpus Striatum; Drug Administration Schedule; Female; Humans; Male; Piperazines; Psychotic Disorders; Pyrimidinones; Raclopride; Receptors, Dopamine D2; Receptors, Serotonin, 5-HT2; Schizophrenia; Thiazoles; Tomography, Emission-Computed	2004
Occupancy of striatal and extrastriatal dopamine D2/D3 receptors by olanzapine and haloperidol. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:12 Topics: Adult; Antipsychotic Agents; Benzamides; Benzodiazepines; Brain Chemistry; Corpus Striatum; Dopamine Antagonists; Female; Haloperidol; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Olanzapine; Positron-Emission Tomography; Pyrimidinones; Pyrrolidines; Radiopharmaceuticals; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D3; Schizophrenia; Serotonin Antagonists	2005
Differential effects of aripiprazole on D(2), 5-HT(2), and 5-HT(1A) receptor occupancy in patients with schizophrenia: a triple tracer PET study. The American journal of psychiatry, 2007, Volume: 164, Issue:9 Topics: Adult; Antipsychotic Agents; Aripiprazole; Basal Ganglia; Basal Ganglia Diseases; Carbon Radioisotopes; Caudate Nucleus; Cerebral Cortex; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorine Radioisotopes; Humans; Male; Piperazines; Positron-Emission Tomography; Psychotic Disorders; Putamen; Pyridines; Pyrimidinones; Quinolones; Raclopride; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine; Receptors, Dopamine D2; Schizophrenia; Serotonin 5-HT1 Receptor Agonists; Treatment Outcome	2007

Other Studies

47 other study(ies) available for setoperone and pyrimidinones

Article	Year
Blood-cerebrospinal fluid and blood-brain barriers imaged by 18F-labeled metabolites of 18F-setoperone studied in humans using positron emission tomography. Journal of neurochemistry, 1992, Volume: 58, Issue:6 Topics: Adult; Blood-Brain Barrier; Brain; Cerebellum; Cerebral Cortex; Fluorine Radioisotopes; Humans; Pyrimidinones; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Tomography, Emission-Computed	1992
A method for the in vivo investigation of the serotonergic 5-HT2 receptors in the human cerebral cortex using positron emission tomography and 18F-labeled setoperone. Journal of neurochemistry, 1990, Volume: 54, Issue:5 Topics: Adult; Aged; Brain; Cerebral Cortex; Fluorine Radioisotopes; Humans; Kinetics; Male; Middle Aged; Pyrimidinones; Receptors, Serotonin; Sensitivity and Specificity; Serotonin Antagonists; Tissue Distribution; Tomography, Emission-Computed	1990
5-HT2-receptor antagonists: alpha 1- vs. 5-HT2-receptor blocking properties in blood vessels. Journal of cardiovascular pharmacology, 1988, Volume: 11 Suppl 1 Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Ergolines; Ketanserin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phentolamine; Piperidines; Pyrimidinones; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Spiperone	1988
Effects of 5-HT1A agonists and 5-HT2 antagonists on haloperidol-induced dyskinesias in squirrel monkeys: no evidence for reciprocal 5-HT-dopamine interaction. Psychopharmacology, 1989, Volume: 97, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Avoidance Learning; Buspirone; Dopamine; Haloperidol; Male; Movement Disorders; Pyrimidinones; Saimiri; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1989
Effect of typical and atypical antipsychotic drugs on 5-HT2 receptor density in rat cerebral cortex. Life sciences, 1989, Volume: 45, Issue:15 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Butyrophenones; Cerebral Cortex; Chlorpromazine; Clozapine; Dibenzazepines; Dibenzothiazepines; Down-Regulation; Flupenthixol; Kinetics; Loxapine; Male; Pyrimidinones; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiro Compounds; Time Factors	1989
Neuroendocrine effects of setoperone: a new neuroleptic drug. International journal of clinical pharmacology research, 1986, Volume: 6, Issue:6 Topics: Adolescent; Adult; Antipsychotic Agents; Dopamine Antagonists; Humans; Male; Prolactin; Pyrimidinones; Receptors, Serotonin	1986
Antagonism of serotonin receptor mediated neuroendocrine and temperature responses by atypical neuroleptics in the rat. European journal of pharmacology, 1988, Jul-14, Volume: 151, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Body Temperature; Butyrophenones; Chlorpromazine; Clozapine; Corticosterone; Haloperidol; Male; Neurosecretory Systems; Pyrazines; Pyrimidinones; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1988
Differential regulation of dopamine-D2 and serotonin-S2 receptors by chronic treatment with the serotonin-S2 antagonists, ritanserin, and setoperone. Psychopharmacology series, 1987, Volume: 3 Topics: Animals; Brain; Corpus Striatum; Frontal Lobe; Male; Piperidines; Pyrimidinones; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Serotonin; Ritanserin; Serotonin Antagonists	1987
Down regulation of serotonin-S2 receptor sites in rat brain by chronic treatment with the serotonin-S2 antagonists: ritanserin and setoperone. Psychopharmacology, 1986, Volume: 88, Issue:4 Topics: Animals; Brain; Corpus Striatum; Frontal Lobe; Ketanserin; Male; Piperidines; Pyrimidinones; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Neurotransmitter; Receptors, Serotonin; Ritanserin	1986
Synthesis, affinity and specificity of 18F-setoperone, a potential ligand for in-vivo imaging of cortical serotonin receptors. International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1988, Volume: 15, Issue:4 Topics: Animals; Autoradiography; Brain; Brain Chemistry; Fluorine Radioisotopes; In Vitro Techniques; Isotope Labeling; Male; Pyrimidinones; Radionuclide Imaging; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists	1988
[18F]setoperone: a new high-affinity ligand for positron emission tomography study of the serotonin-2 receptors in baboon brain in vivo. European journal of pharmacology, 1988, Feb-16, Volume: 147, Issue:1 Topics: Animals; Brain; Fluorine Radioisotopes; Injections, Intravenous; Ketanserin; Ligands; Male; Papio; Pyrimidinones; Receptors, Serotonin; Serotonin Antagonists; Tomography, Emission-Computed	1988
Opposite regulation of serotonin-S2 and dopamine-D2 receptors in rat brain following chronic receptor blockade. Journal of receptor research, 1987, Volume: 7, Issue:1-4 Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Diazepam; Dopamine Antagonists; Frontal Lobe; Gene Expression Regulation; Ketanserin; Male; Models, Biological; Piperidines; Pyrimidinones; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Serotonin Antagonists; Tryptamines	1987
Effect of serotonin antagonism in schizophrenia: a pilot study with setoperone. Psychopharmacology, 1985, Volume: 85, Issue:3 Topics: Adult; Aged; Basal Ganglia Diseases; Female; Humans; Male; Middle Aged; Pilot Projects; Psychiatric Status Rating Scales; Pyrimidinones; Schizophrenia; Serotonin Antagonists	1985
5HT2 receptors in cerebral cortex of migraineurs studied using PET and 18F-fluorosetoperone. Cephalalgia : an international journal of headache, 1995, Volume: 15, Issue:2 Topics: Adult; Case-Control Studies; Cerebral Cortex; Fluorine Radioisotopes; Humans; Middle Aged; Migraine Disorders; Pyrimidinones; Radioligand Assay; Receptors, Serotonin; Statistics as Topic; Tomography, Emission-Computed	1995
[A study on the pharmacological properties of atypical antipsychotic drugs: in vivo dopamine and serotonin receptor occupancy by atypical antipsychotic drugs in the rat brain]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1993, Volume: 68, Issue:4 Topics: Animals; Antipsychotic Agents; Autoradiography; Brain; Chlorpromazine; Clozapine; Dibenzothiepins; Flupenthixol; Haloperidol; In Vitro Techniques; Isoxazoles; Male; Piperidines; Pyrimidinones; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Serotonin; Risperidone	1993
Loss of brain 5-HT2 receptors in Alzheimer's disease. In vivo assessment with positron emission tomography and [18F]setoperone. Brain : a journal of neurology, 1993, Volume: 116 ( Pt 3) Topics: Aged; Alzheimer Disease; Cerebral Cortex; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Pyrimidinones; Receptors, Serotonin; Tomography, Emission-Computed, Single-Photon	1993
Estimation of neocortical serotonin-2 receptor binding potential by single-dose fluorine-18-setoperone kinetic PET data analysis. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:1 Topics: Animals; Cerebellum; Cerebral Cortex; Computer Simulation; Feasibility Studies; Fluorine Radioisotopes; Papio; Pyrimidinones; Receptors, Serotonin; Serotonin Antagonists; Tomography, Emission-Computed	1996
Positron emission tomographic analysis of central 5-hydroxytryptamine2 receptor occupancy in healthy volunteers treated with the novel antipsychotic agent, ziprasidone. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:2 Topics: Adult; Antipsychotic Agents; Brain Chemistry; Cerebrovascular Circulation; Humans; Male; Piperazines; Pyrimidinones; Receptors, Serotonin; Serotonin Antagonists; Thiazoles; Tomography, Emission-Computed	1996
Post-stroke changes in cortical 5-HT2 serotonergic receptors. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:12 Topics: Adult; Age Factors; Aged; Cerebral Cortex; Cerebrovascular Disorders; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Pyrimidinones; Receptors, Serotonin; Tomography, Emission-Computed	1996
Cyproheptadine: a potent in vivo serotonin antagonist. The American journal of psychiatry, 1997, Volume: 154, Issue:6 Topics: Adult; Cyproheptadine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Fluorine Radioisotopes; Humans; Male; Prefrontal Cortex; Pyrimidinones; Receptors, Dopamine D2; Receptors, Serotonin; Serotonin Antagonists; Tomography, Emission-Computed	1997
Reliability of a simple non-invasive method for the evaluation of 5-HT2 receptors using [18F]-setoperone PET imaging. Nuclear medicine communications, 1997, Volume: 18, Issue:5 Topics: Adult; Brain; Cerebellum; Female; Fluorine Radioisotopes; Humans; Male; Pyrimidinones; Receptors, Serotonin; Reference Values; Reproducibility of Results; Serotonin Antagonists; Tomography, Emission-Computed	1997
Frontal 5-HT2A receptors studied in depressive patients during chronic treatment by selective serotonin reuptake inhibitors. Psychopharmacology, 1997, Volume: 133, Issue:1 Topics: Adult; Antidepressive Agents; Depressive Disorder; Female; Fluorine Radioisotopes; Frontal Lobe; Humans; Male; Middle Aged; Pyrimidinones; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Tomography, Emission-Computed	1997
PET evidence that loxapine is an equipotent blocker of 5-HT2 and D2 receptors: implications for the therapeutics of schizophrenia. The American journal of psychiatry, 1997, Volume: 154, Issue:11 Topics: Adult; Cerebellum; Corpus Striatum; Dopamine Antagonists; Female; Fluorine Radioisotopes; Humans; Loxapine; Male; Pyrimidinones; Raclopride; Receptors, Dopamine D2; Receptors, Serotonin; Salicylamides; Schizophrenia; Tomography, Emission-Computed	1997
Binding of antipsychotic drugs to cortical 5-HT2A receptors: a PET study of chlorpromazine, clozapine, and amisulpride in schizophrenic patients. The American journal of psychiatry, 1998, Volume: 155, Issue:4 Topics: Adolescent; Adult; Amisulpride; Animals; Antipsychotic Agents; Cerebral Cortex; Chlorpromazine; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorine Radioisotopes; Humans; Male; Pyrimidinones; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Schizophrenia; Sulpiride; Tomography, Emission-Computed	1998
No serotonin 5-HT2A receptor density abnormality in the cortex of schizophrenic patients studied with PET. Schizophrenia research, 1998, May-04, Volume: 31, Issue:1 Topics: Adult; Cell Count; Cerebral Cortex; Female; Functional Laterality; Humans; Male; Pyrimidinones; Receptors, Serotonin; Schizophrenia; Tomography, Emission-Computed	1998
Serotonin 5-HT2 receptors in schizophrenia: a PET study using [18F]setoperone in neuroleptic-naive patients and normal subjects. The American journal of psychiatry, 1999, Volume: 156, Issue:1 Topics: Antipsychotic Agents; Brain Chemistry; Cerebral Cortex; Contrast Media; Fluorine Radioisotopes; Humans; Prefrontal Cortex; Pyrimidinones; Receptors, Serotonin; Schizophrenia; Tomography, Emission-Computed	1999
Parametric PET imaging of 5HT2A receptor distribution with 18F-setoperone in the normal human neocortex. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1999, Volume: 40, Issue:1 Topics: Adult; Cerebellum; Fluorine Radioisotopes; Humans; Imidazoles; Indoles; Male; Neocortex; Pyrimidinones; Radiopharmaceuticals; Receptors, Serotonin; Serotonin Antagonists; Tomography, Emission-Computed	1999
Clinical and theoretical implications of 5-HT2 and D2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia. The American journal of psychiatry, 1999, Volume: 156, Issue:2 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Carbon Radioisotopes; Clozapine; Drug Administration Schedule; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Olanzapine; Pirenzepine; Pyrimidinones; Raclopride; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Salicylamides; Schizophrenia; Tomography, Emission-Computed	1999
Prefrontal cortex 5-HT2 receptors in depression: an [18F]setoperone PET imaging study. The American journal of psychiatry, 1999, Volume: 156, Issue:7 Topics: Adolescent; Adult; Age Factors; Depressive Disorder; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Prefrontal Cortex; Pyrimidinones; Receptors, Serotonin; Research Design; Suicide, Attempted; Tomography, Emission-Computed	1999
The effects of single dose nefazodone and paroxetine upon 5-HT2A binding potential in humans using [18F]-setoperone PET. Psychopharmacology, 1999, Volume: 144, Issue:3 Topics: Adult; Analysis of Variance; Antidepressive Agents; Binding, Competitive; Female; Fluorine Radioisotopes; Humans; Male; Paroxetine; Piperazines; Pyrimidinones; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Tomography, Emission-Computed; Triazoles	1999
Decrease in brain serotonin 2 receptor binding in patients with major depression following desipramine treatment: a positron emission tomography study with fluorine-18-labeled setoperone. Archives of general psychiatry, 1999, Volume: 56, Issue:8 Topics: Antidepressive Agents, Tricyclic; Brain; Depressive Disorder; Desipramine; Down-Regulation; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Frontal Lobe; Humans; Occipital Lobe; Pyrimidinones; Receptors, Serotonin; Tomography, Emission-Computed	1999
Decreased serotonin 2A receptor densities in neuroleptic-naive patients with schizophrenia: A PET study using [(18)F]setoperone. The American journal of psychiatry, 2000, Volume: 157, Issue:6 Topics: Adolescent; Adult; Antipsychotic Agents; Brain; Female; Fluorine Radioisotopes; Frontal Lobe; Humans; Male; Pyrimidinones; Radionuclide Imaging; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Schizophrenia	2000
Brain serotonin2 receptors in major depression: a positron emission tomography study. Archives of general psychiatry, 2000, Volume: 57, Issue:9 Topics: Adult; Age Factors; Brain; Cerebellum; Depressive Disorder; Female; Fluorine Radioisotopes; Frontal Lobe; Humans; Male; Middle Aged; Occipital Lobe; Parietal Lobe; Pyrimidinones; Receptors, Serotonin; Sex Factors; Temporal Lobe; Tomography, Emission-Computed	2000
A PET study of brain 5-HT2 receptors and their correlation with platelet 5-HT2 receptors in healthy humans. Psychopharmacology, 2000, Volume: 151, Issue:4 Topics: Adult; Blood Platelets; Brain Chemistry; Female; Humans; Lysergic Acid Diethylamide; Male; Middle Aged; Pyrimidinones; Receptors, Serotonin; Tomography, Emission-Computed	2000
A voxel-by-voxel analysis of [18F]setoperone PET data shows no substantial serotonin 5-HT(2A) receptor changes in schizophrenia. Psychiatry research, 2000, Oct-30, Volume: 99, Issue:3 Topics: Adult; Age Factors; Analysis of Variance; Brain; Case-Control Studies; Contrast Media; Female; Fluorine Radioisotopes; Humans; Male; Psychiatric Status Rating Scales; Pyrimidinones; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Schizophrenia; Schizophrenic Psychology; Serotonin Antagonists; Tomography, Emission-Computed	2000
The effect of paroxetine on 5-HT(2A) receptors in depression: an [(18)F]setoperone PET imaging study. The American journal of psychiatry, 2001, Volume: 158, Issue:1 Topics: Adolescent; Adult; Age Factors; Cerebral Cortex; Depressive Disorder; Down-Regulation; Female; Fluorine Radioisotopes; Humans; Male; Paroxetine; Pyrimidinones; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Tomography, Emission-Computed; Treatment Outcome	2001
Effects of rapid tryptophan depletion on brain 5-HT(2) receptors: a PET study. The British journal of psychiatry : the journal of mental science, 2001, Volume: 178 Topics: Adult; Affect; Brain; Female; Fluorine Radioisotopes; Humans; Middle Aged; Pyrimidinones; Receptors, Serotonin; Serotonin Antagonists; Tomography, Emission-Computed; Tryptophan	2001
Electroconvulsive shock decreases binding to 5-HT2 receptors in nonhuman primates: an in vivo positron emission tomography study with [18F]setoperone. Biological psychiatry, 2005, May-01, Volume: 57, Issue:9 Topics: Analysis of Variance; Animals; Brain; Dose-Response Relationship, Radiation; Electroshock; Fluorine Radioisotopes; Macaca mulatta; Male; Positron-Emission Tomography; Protein Binding; Pyrimidinones; Receptors, Serotonin, 5-HT2; Seizures; Serotonin Antagonists; Time Factors; Tomography, Emission-Computed	2005
A positron emission tomography study of the effects of treatment with valproate on brain 5-HT2A receptors in acute mania. Bipolar disorders, 2005, Volume: 7 Suppl 5 Topics: Acute Disease; Adult; Antimanic Agents; Bipolar Disorder; Brain; Contrast Media; Female; Humans; Lithium; Male; Middle Aged; Positron-Emission Tomography; Pyrimidinones; Receptor, Serotonin, 5-HT2A; Valproic Acid	2005
Cortical serotonin type-2 receptor density in parents of children with autism spectrum disorders. Journal of autism and developmental disorders, 2009, Volume: 39, Issue:1 Topics: Adult; Autistic Disorder; Cerebral Cortex; Child; Female; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Phenotype; Pyrimidinones; Radionuclide Imaging; Receptors, Serotonin, 5-HT2; Reference Values; Serotonin Antagonists	2009
Test-retest variability of high resolution positron emission tomography (PET) imaging of cortical serotonin (5HT2A) receptors in older, healthy adults. BMC medical imaging, 2009, Jul-06, Volume: 9 Topics: Aged; Brain; Female; Humans; Image Enhancement; Male; Positron-Emission Tomography; Pyrimidinones; Radiopharmaceuticals; Receptors, Serotonin; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Tissue Distribution	2009
Is desire for social relationships mediated by the serotonergic system in the prefrontal cortex? An [(18)F]setoperone PET study. Social neuroscience, 2010, Volume: 5, Issue:4 Topics: Adolescent; Adult; Brain Mapping; Contrast Media; Female; Humans; Male; Middle Aged; Personality Tests; Positron-Emission Tomography; Prefrontal Cortex; Pyrimidinones; Receptor, Serotonin, 5-HT2A; Social Behavior; Young Adult	2010
Serotonin 2A receptors and visual hallucinations in Parkinson disease. Archives of neurology, 2010, Volume: 67, Issue:4 Topics: Aged; Brain; Brain Mapping; Case-Control Studies; Female; Hallucinations; Humans; Male; Middle Aged; Parkinson Disease; Pilot Projects; Positron-Emission Tomography; Pyrimidinones; Receptor, Serotonin, 5-HT2A; Serotonin; Serotonin Antagonists; Temporal Lobe; Visual Cortex; Visual Pathways	2010
Effect of electroconvulsive therapy on brain 5-HT(2) receptors in major depression. The British journal of psychiatry : the journal of mental science, 2010, Volume: 196, Issue:6 Topics: Adolescent; Adult; Aged; Brain Mapping; Contrast Media; Depressive Disorder, Major; Down-Regulation; Electroconvulsive Therapy; Female; Humans; Male; Middle Aged; Pyrimidinones; Receptors, Serotonin, 5-HT2; Treatment Outcome; Young Adult	2010
Effects of aging on 5-HT(2A) R binding: a HRRT PET study with and without partial volume corrections. International journal of geriatric psychiatry, 2011, Volume: 26, Issue:12 Topics: Adult; Aged; Aging; Brain; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Positron-Emission Tomography; Pyrimidinones; Radioisotopes; Receptor, Serotonin, 5-HT2A; Young Adult	2011
Evidence for chronically altered serotonin function in the cerebral cortex of female 3,4-methylenedioxymethamphetamine polydrug users. Archives of general psychiatry, 2012, Volume: 69, Issue:4 Topics: Adolescent; Adult; Amphetamine-Related Disorders; Cerebral Cortex; Female; Fluorine Radioisotopes; Functional Neuroimaging; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Positron-Emission Tomography; Pyrimidinones; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Serotonin Antagonists; Substance-Related Disorders; Time Factors	2012
5-HT2 receptor distribution shown by [18F] setoperone PET in high-functioning autistic adults. The Journal of neuropsychiatry and clinical neurosciences, 2012,Spring, Volume: 24, Issue:2 Topics: Adult; Autistic Disorder; Brain; Case-Control Studies; Female; Fluorine Radioisotopes; Functional Neuroimaging; Humans; Language Disorders; Male; Pilot Projects; Positron-Emission Tomography; Pyrimidinones; Radioligand Assay; Radiopharmaceuticals; Receptors, Serotonin, 5-HT2; Thalamus	2012