Page last updated: 2024-08-24

sertindole and ziprasidone

sertindole has been researched along with ziprasidone in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (17.95)18.2507
2000's18 (46.15)29.6817
2010's11 (28.21)24.3611
2020's3 (7.69)2.80

Authors

AuthorsStudies
De Loore, K; Gommeren, W; Janssen, PF; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van Gompel, P1
Arnt, J; Skarsfeldt, T1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L1
Grinde, E; Herrick-Davis, K; Teitler, M1
Chen, XL; Kang, J; Kongsamut, S; Rampe, D; Roehr, J1
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M1
Ernsberger, P; Hufeisen, SJ; Jayathilake, K; Kroeze, WK; Meltzer, HY; Popadak, BA; Renock, SM; Roth, BL; Steinberg, S1
Wermuth, CG1
Li, J; Rajamani, R; Reynolds, CH; Tounge, BA1
Nagashima, R; Nishikawa, T; Tobita, M1
Jia, L; Sun, H1
Caron, G; Ermondi, G; Visentin, S1
Giordanetto, F; Leach, AG; Zachariae, U1
Duncton, MA; Emerling, DE; Kelly, MG; Nguyen, MT; Vincent, F1
Jensen, AA; Kehler, J; Krogsgaard-Larsen, N1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Sen, S; Sinha, N1
Broccatelli, F; Carosati, E; Cruciani, G; Frosini, M; Goracci, L; Neri, A; Oprea, TI1
Brincat, JP; Broccatelli, F; Carosati, E; Cruciani, G; Frosini, M; Kaatz, GW; Neri, A; Sabatini, S1
Lahti, AC; Tamminga, CA1
Davidson, M; Levy, A; Weizer, M1
Kane, JM1
Bayle, FJ; Ghaoui, S; Olie, JP1
Möller, HJ1
McAskill, R; Taylor, DM1
Kapur, S; Remington, G1
Hilger, E; Kasper, S1
Danileviciūte, V1
Hedges, D; Jeppson, K; Whitehead, P1
Bryois, Ch; Sahli, Ch1
Davis, JM; Hunger, H; Kissling, W; Komossa, K; Leucht, S; Lobos, CA; Rummel-Kluge, C; Schmid, F; Schwarz, S1
Hunger, H; Kissling, W; Komossa, K; Leucht, S; Rummel-Kluge, C; Schmid, F; Schwarz, S1
Lerner, V; Miodownik, C; Witztum, E1
Blagojević, D; Lečić-Toševski, D; Miljević, Č; Niketić, V; Nikolić, M; Nikolić-Kokić, A; Spasić, MB1
Blagojević, D; Mijušković, A; Miler, M; Miljević, Č; Milošević, V; Nestorov, J; Nikolić, M; Nikolić-Kokić, A; Oreščanin-Dušić, Z; Spasić, M; Tatalović, N1
Blagojević, D; Mijović, M; Mijusković, A; Miler, M; Miljević, Č; Milošević, V; Nestorov, J; Nikolić, M; Nikolić-Kokić, A; Oreščanin-Dušić, Z; Spasić, M; Tatalović, N1
Crippa, A; Davis, JM; Leucht, S; Orsini, N; Patel, MX; Siafis, S1
Blagojević, D; Brkljačić, J; Miler, M; Miljević, Č; Milošević, V; Nikolić, M; Nikolić-Kokić, A; Oreščanin-Dušić, Z; Platanić Arizanović, L; Spasić, S; Tatalović, N; Vidonja Uzelac, T1
Cvijetić, I; Gligorijević, N; Kokić, AN; Mijatović, A; Miljević, Č; Minić, S; Nikolić, M; Platanić Arizanović, L; Ristivojević, MK1

Reviews

16 review(s) available for sertindole and ziprasidone

ArticleYear
Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1998, Volume: 18, Issue:2

    Topics: Animals; Antipsychotic Agents; Humans

1998
Selective optimization of side activities: another way for drug discovery.
    Journal of medicinal chemistry, 2004, Mar-11, Volume: 47, Issue:6

    Topics: Animals; Biological Availability; Combinatorial Chemistry Techniques; Databases, Factual; Drug Design; Humans; Patents as Topic; Pharmaceutical Preparations; Structure-Activity Relationship

2004
The new generation of antipsychotic drugs.
    International clinical psychopharmacology, 1996, Volume: 11 Suppl 2

    Topics: Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Schizophrenia; Thiazoles

1996
[New antipsychotic drugs].
    Harefuah, 1997, Volume: 133, Issue:1-2

    Topics: Antipsychotic Agents; Benzodiazepines; Benzothiazoles; Clinical Trials as Topic; Dibenzothiazepines; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Pramipexole; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Thiazoles

1997
Tardive dyskinesia in affective disorders.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 5

    Topics: Adult; Affective Disorders, Psychotic; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Controlled Clinical Trials as Topic; Dibenzothiazepines; Drug Administration Schedule; Dyskinesia, Drug-Induced; Female; Humans; Imidazoles; Indoles; Male; Olanzapine; Piperazines; Pirenzepine; Psychotic Disorders; Quetiapine Fumarate; Risk Assessment; Risk Factors; Risperidone; Schizophrenia; Thiazoles; Treatment Outcome

1999
[New antipsychotic agents].
    L'Encephale, 1999, Volume: 25 Spec No 3

    Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Sulpiride; Thiazoles

1999
[New i.e. atypical neuroleptic agents for negative symptoms of schizophrenia: results and methodological problems of evaluation].
    Der Nervenarzt, 2000, Volume: 71, Issue:5

    Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dibenzothiepins; Double-Blind Method; Dyskinesia, Drug-Induced; Humans; Imidazoles; Indoles; Neurotransmitter Agents; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Schizophrenic Psychology; Sulpiride; Thiazoles

2000
Atypical antipsychotics and weight gain--a systematic review.
    Acta psychiatrica Scandinavica, 2000, Volume: 101, Issue:6

    Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dibenzothiepins; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Risperidone; Sulpiride; Thiazoles; Weight Gain

2000
Atypical antipsychotics: new directions and new challenges in the treatment of schizophrenia.
    Annual review of medicine, 2001, Volume: 52

    Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dibenzothiepins; Dopamine Antagonists; Drug Monitoring; Haloperidol; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Receptors, Dopamine D2; Receptors, Dopamine D4; Risperidone; Schizophrenia; Schizophrenic Psychology; Serotonin Antagonists; Sulpiride; Thiazoles; Treatment Outcome

2001
[Atypical neuroleptics: new approaches to drug therapy of schizophrenic disorders].
    Wiener klinische Wochenschrift, 2000, Dec-22, Volume: 112, Issue:24

    Topics: Aged; Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Controlled Clinical Trials as Topic; Dibenzothiazepines; Dibenzothiepins; Haloperidol; Humans; Imidazoles; Indoles; Multicenter Studies as Topic; Olanzapine; Piperazines; Pirenzepine; Placebos; Quetiapine Fumarate; Risperidone; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sulpiride; Thiazoles

2000
[Schizoaffective disorder: clinical symptoms and present-day approach to treatment].
    Medicina (Kaunas, Lithuania), 2002, Volume: 38, Issue:11

    Topics: Adolescent; Amisulpride; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Child; Diagnosis, Differential; Dibenzothiazepines; Dogs; Female; Humans; Imidazoles; Indoles; Lithium Carbonate; Male; Mianserin; Middle Aged; Mirtazapine; Olanzapine; Piperazines; Pirenzepine; Placebos; Prognosis; Psychotic Disorders; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Sulpiride; Thiazoles; Time Factors

2002
Antipsychotic medication and seizures: a review.
    Drugs of today (Barcelona, Spain : 1998), 2003, Volume: 39, Issue:7

    Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clinical Trials as Topic; Clozapine; Dibenzothiazepines; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Quinolones; Risperidone; Seizures; Thiazoles

2003
[Psychotropics and weight gain].
    Praxis, 2004, Aug-25, Volume: 93, Issue:35

    Topics: Adolescent; Adult; Amisulpride; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Body Mass Index; Child; Clozapine; Dibenzothiazepines; Double-Blind Method; Female; Fructose; Haloperidol; Humans; Imidazoles; Indoles; Male; Obesity; Olanzapine; Piperazines; Placebos; Psychotropic Drugs; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Socioeconomic Factors; Sulpiride; Thiazoles; Time Factors; Topiramate; Valproic Acid; Weight Gain

2004
Head-to-head comparisons of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: a systematic review and meta-analysis.
    Schizophrenia research, 2010, Volume: 123, Issue:2-3

    Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Blood Glucose; Cholesterol; Clinical Trials as Topic; Clozapine; Dibenzothiazepines; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Sulpiride; Thiazoles; Weight Gain

2010
Risperidone versus other atypical antipsychotics for schizophrenia.
    The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1

    Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Sulpiride; Thiazoles

2011
Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia.
    The American journal of psychiatry, 2020, 04-01, Volume: 177, Issue:4

    Topics: Acute Disease; Administration, Oral; Antipsychotic Agents; Aripiprazole; Clozapine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Haloperidol; Humans; Imidazoles; Indoles; Isoxazoles; Lurasidone Hydrochloride; Olanzapine; Paliperidone Palmitate; Piperazines; Piperidines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Schizophrenic Psychology; Thiazoles; Thiophenes

2020

Other Studies

23 other study(ies) available for sertindole and ziprasidone

ArticleYear
Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding.
    Psychopharmacology, 1996, Volume: 124, Issue:1-2

    Topics: Animals; Antipsychotic Agents; Brain; Cells, Cultured; Clozapine; Haloperidol; Humans; Male; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Serotonin; Risperidone

1996
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
    European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3

    Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes

1998
Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1

    Topics: Animals; Antipsychotic Agents; COS Cells; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Radioligand Assay; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Receptor Agonists

2000
A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs.
    European journal of pharmacology, 2002, Aug-16, Volume: 450, Issue:1

    Topics: Animals; Antipsychotic Agents; Cation Transport Proteins; Cell Line; Clinical Trials as Topic; Cricetinae; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Long QT Syndrome; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Trans-Activators; Transcriptional Regulator ERG

2002
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
    Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18

    Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2002
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:3

    Topics: Animals; Antipsychotic Agents; Discriminant Analysis; Drug Evaluation, Preclinical; Forecasting; Humans; Protein Binding; Receptors, Histamine H1; Statistics, Nonparametric; Weight Gain

2003
A two-state homology model of the hERG K+ channel: application to ligand binding.
    Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation

2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:5

    Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship

2009
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers.
    Journal of medicinal chemistry, 2009, Jul-23, Volume: 52, Issue:14

    Topics: Binding Sites; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Potassium Channel Blockers; Protein Binding; Protein Conformation

2009
Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors.
    Bioorganic & medicinal chemistry letters, 2009, Dec-01, Volume: 19, Issue:23

    Topics: Amidohydrolases; Carbamates; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Structure; Piperazines; Stereoisomerism; Structure-Activity Relationship

2009
Novel 7-phenylsulfanyl-1,2,3,4,10,10a-hexahydro-pyrazino[1,2-a]indoles as dual serotonin 5-HT2C and 5-HT6 receptor ligands.
    Bioorganic & medicinal chemistry letters, 2010, Sep-15, Volume: 20, Issue:18

    Topics: Cell Line; HeLa Cells; Humans; Indoles; Ligands; Protein Binding; Pyrazines; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Structure-Activity Relationship

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
A novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecular interaction fields.
    Journal of medicinal chemistry, 2011, Mar-24, Volume: 54, Issue:6

    Topics: Animals; Aripiprazole; ATP Binding Cassette Transporter, Subfamily B, Member 1; Butyrophenones; Cell Line, Tumor; Cell Membrane Permeability; Drug Design; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Mice; Models, Molecular; Molecular Structure; Piperazines; Piperidines; Protein Binding; Quantitative Structure-Activity Relationship; Quinolones

2011
Ligand Promiscuity between the Efflux Pumps Human P-Glycoprotein and S. aureus NorA.
    ACS medicinal chemistry letters, 2012, Mar-08, Volume: 3, Issue:3

    Topics:

2012
Pisa syndrome and laryngeal dystonia induced by novel antipsychotics.
    The Israel journal of psychiatry and related sciences, 2011, Volume: 48, Issue:3

    Topics: Adult; Antipsychotic Agents; Dystonia; Humans; Imidazoles; Indoles; Laryngeal Diseases; Male; Middle Aged; Piperazines; Risperidone; Schizophrenia; Syndrome; Thiazoles

2011
Effect of atypical antipsychotics on antioxidant enzyme activities in human erythrocytes (in vitro study).
    Human psychopharmacology, 2013, Volume: 28, Issue:1

    Topics: Adult; Amisulpride; Antioxidants; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Catalase; Clozapine; Dibenzothiazepines; Enzyme Activation; Erythrocytes; Glutathione Peroxidase; Glutathione Reductase; Humans; Imidazoles; Indoles; Male; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Sulpiride; Superoxide Dismutase; Superoxide Dismutase-1; Thiazoles; Treatment Outcome; Young Adult

2013
Effects of antipsychotic drug administration on antioxidative defense enzymes in male rat kidney.
    Journal of toxicology and environmental health. Part A, 2016, Volume: 79, Issue:20

    Topics: Animals; Antioxidants; Antipsychotic Agents; Clozapine; Imidazoles; Indoles; Kidney; Male; Oxidative Stress; Piperazines; Random Allocation; Rats; Rats, Wistar; Thiazoles

2016
Clozapine, ziprasidone, and sertindole-induced morphological changes in the rat heart and their relationship to antioxidant enzymes function.
    Journal of toxicology and environmental health. Part A, 2018, Volume: 81, Issue:17

    Topics: Animals; Antioxidants; Antipsychotic Agents; Clozapine; Heart; Imidazoles; Indoles; Male; Myocardium; Oxidation-Reduction; Piperazines; Rats; Rats, Wistar; Thiazoles

2018
Effects of several atypical antipsychotics closapine, sertindole or ziprasidone on hepatic antioxidant enzymes: Possible role in drug-induced liver dysfunction.
    Journal of toxicology and environmental health. Part A, 2021, 02-16, Volume: 84, Issue:4

    Topics: Animals; Antioxidants; Antipsychotic Agents; Clozapine; Imidazoles; Indoles; Liver; Liver Diseases; Male; Piperazines; Rats; Rats, Wistar; Thiazoles

2021
Human Hemoglobin and Antipsychotics Clozapine, Ziprasidone and Sertindole: Friends or Foes?
    International journal of molecular sciences, 2023, May-17, Volume: 24, Issue:10

    Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Molecular Docking Simulation; Olanzapine

2023