Page last updated: 2024-08-24

sertindole and haloperidol

sertindole has been researched along with haloperidol in 60 studies

Research

Studies (60)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	20 (33.33)	18.2507
2000's	29 (48.33)	29.6817
2010's	10 (16.67)	24.3611
2020's	1 (1.67)	2.80

Authors

Authors	Studies
Arnt, J; Bøgesø, KP; Hyttel, J; Perregaard, J; Sánchez, C	1
De Loore, K; Gommeren, W; Janssen, PF; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van Gompel, P	1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L	1
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M	1
Andersen, K; Balle, T; Larsen, AK; Liljefors, T; Perregaard, J; Ramirez, MT; Søby, KK	1
Ernsberger, P; Hufeisen, SJ; Jayathilake, K; Kroeze, WK; Meltzer, HY; Popadak, BA; Renock, SM; Roth, BL; Steinberg, S	1
Chen, XL; Hendrix, J; Kang, J; Korolev, AM; Lysenkova, LN; Miroshnikova, OV; Pearlstein, RA; Preobrazhenskaya, M; Rampe, D; Shchekotikhin, AE; Vaz, RJ	1
Keserü, GM	1
Wermuth, CG	1
Li, J; Rajamani, R; Reynolds, CH; Tounge, BA	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Bariwal, JB; Chauhan, BS; Jain, KS; Kathiravan, MK; Phoujdar, MS; Sahne, RS; Shah, AK; Yadav, MR	1
Jia, L; Sun, H	1
Caron, G; Ermondi, G; Visentin, S	1
Giordanetto, F; Leach, AG; Zachariae, U	1
Sen, S; Sinha, N	1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A	1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bienkowski, P; Bucki, A; Jaśkowska, J; Kazek, G; Kowalski, P; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Mitka, K; Pawłowski, M; Siwek, A; Wasik, A; Wesołowska, A	1
Skarsfeldt, T	2
Arnt, J	1
Misawa, M; Suzuki, T	1
Casey, DE	1
Daniel, DG; Kane, JM; Kashkin, KB; Mack, RJ; Sebree, TB; Tamminga, CA; Wallin, BA; Wozniak, PJ; Zimbroff, DL	1
Fogelson, DL; Payne, D; Sternbach, H	1
Daniel, DG; Mack, RJ; McCarthy, BG; Wozniak, P	1
Asenbaum, S; Barnas, C; Brücke, T; Hesselmann, B; Kasper, S; Küfferle, B; Podreka, I; Tauscher, J	1
Kane, JM	1
Balon, R	1
Mattes, JA	1
Gao, XM; Sakai, K; Tamminga, CA	1
Depoortere, R; Perrault, G; Sanger, DJ	1
Drici, MD; Flockhart, DA; Liu, XK; Wang, WX; Woosley, RL	1
Abraham, D; Kissling, W; Leucht, S; Pitschel-Walz, G	1
Berisford, MA; Goldstein, D; Kysar, L; Marder, SR; Mintz, J; Pashdag, J; Wirshing, DA; Wirshing, WC	1
Kapur, S; Remington, G	1
Gao, XM; Hashimoto, T; Sakai, K; Tamminga, CA	1
Hilger, E; Kasper, S	1
Andersen, MP; Pouzet, B	1
Philibin, SD; Porter, JH; Vann, RE; Varvel, SA; Wise, LE	1
Bryois, Ch; Sahli, Ch	1
Perquin, LN	1
Hertel, P	1
Arnt, J; Didriksen, M; Skarsfeldt, T	1
Chu, K; Jung, KH; Lee, SK; Nam, H; Park, KI; Sinn, DI	1
Gallhofer, B; Jaanson, P; Krieger, S; Lis, S; Mittoux, A; Tanghøj, P	1
Seeman, P	1
Brennum, LT; Kreilgaard, M; Olsen, CK	1
Dias, R; Goetghebeur, P	1
Kristensen, T; Mulvany, MJ; Nielsen, KB; Nourian, Z; Pickering, DS	1
Arnt, J; Mørk, A; Witten, LM	1
Buchsbaum, MS; Chu, KW; Dusi, N; Entis, JJ; Goldstein, KE; Goodman, CR; Gupta, A; Hazlett, E; Haznedar, M; Iannuzzi, J; Newmark, RE; Torosjan, Y; Wolkin, A; Zhang, J	1
Andreasson, K; Bech, P; Overø, KF; Tanghøj, P	1
Arnt, J; Bravi, D; de Bartolomeis, A; Iasevoli, F; Marmo, F; Tomasetti, C	1
Buckley, PF; Daniel, DG; Kane, JM; Potkin, SG	1
Eberhard, J; Fors, BM; Hansen, K; Lindström, E; Sapin, C	1
Azorin, JM; Hale, AS; Lemming, OM; Mæhlum, E	1
Crippa, A; Davis, JM; Leucht, S; Orsini, N; Patel, MX; Siafis, S	1

Reviews

8 review(s) available for sertindole and haloperidol

Article	Year
Selective optimization of side activities: another way for drug discovery. Journal of medicinal chemistry, 2004, Mar-11, Volume: 47, Issue:6 Topics: Animals; Biological Availability; Combinatorial Chemistry Techniques; Databases, Factual; Drug Design; Humans; Patents as Topic; Pharmaceutical Preparations; Structure-Activity Relationship	2004
Recent advances in selective alpha1-adrenoreceptor antagonists as antihypertensive agents. Bioorganic & medicinal chemistry, 2008, May-01, Volume: 16, Issue:9 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Humans; Hypertension; Molecular Structure; Receptors, Adrenergic, alpha-1; Risk Factors; Stereoisomerism; Structure-Activity Relationship	2008
Sertindole: a review of clinical efficacy. International clinical psychopharmacology, 1998, Volume: 13 Suppl 3 Topics: Antipsychotic Agents; Clinical Trials as Topic; Depression; Haloperidol; Humans; Imidazoles; Indoles; Neurologic Examination; Psychiatric Status Rating Scales; Schizophrenia; Treatment Outcome	1998
Efficacy and extrapyramidal side-effects of the new antipsychotics olanzapine, quetiapine, risperidone, and sertindole compared to conventional antipsychotics and placebo. A meta-analysis of randomized controlled trials. Schizophrenia research, 1999, Jan-04, Volume: 35, Issue:1 Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Dibenzothiazepines; Double-Blind Method; Haloperidol; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia	1999
Atypical antipsychotics: new directions and new challenges in the treatment of schizophrenia. Annual review of medicine, 2001, Volume: 52 Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dibenzothiepins; Dopamine Antagonists; Drug Monitoring; Haloperidol; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Receptors, Dopamine D2; Receptors, Dopamine D4; Risperidone; Schizophrenia; Schizophrenic Psychology; Serotonin Antagonists; Sulpiride; Thiazoles; Treatment Outcome	2001
[Atypical neuroleptics: new approaches to drug therapy of schizophrenic disorders]. Wiener klinische Wochenschrift, 2000, Dec-22, Volume: 112, Issue:24 Topics: Aged; Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Controlled Clinical Trials as Topic; Dibenzothiazepines; Dibenzothiepins; Haloperidol; Humans; Imidazoles; Indoles; Multicenter Studies as Topic; Olanzapine; Piperazines; Pirenzepine; Placebos; Quetiapine Fumarate; Risperidone; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sulpiride; Thiazoles	2000
[Psychotropics and weight gain]. Praxis, 2004, Aug-25, Volume: 93, Issue:35 Topics: Adolescent; Adult; Amisulpride; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Body Mass Index; Child; Clozapine; Dibenzothiazepines; Double-Blind Method; Female; Fructose; Haloperidol; Humans; Imidazoles; Indoles; Male; Obesity; Olanzapine; Piperazines; Placebos; Psychotropic Drugs; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Socioeconomic Factors; Sulpiride; Thiazoles; Time Factors; Topiramate; Valproic Acid; Weight Gain	2004
Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia. The American journal of psychiatry, 2020, 04-01, Volume: 177, Issue:4 Topics: Acute Disease; Administration, Oral; Antipsychotic Agents; Aripiprazole; Clozapine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Haloperidol; Humans; Imidazoles; Indoles; Isoxazoles; Lurasidone Hydrochloride; Olanzapine; Paliperidone Palmitate; Piperazines; Piperidines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Schizophrenic Psychology; Thiazoles; Thiophenes	2020

Trials

8 trial(s) available for sertindole and haloperidol

Article	Year
Controlled, dose-response study of sertindole and haloperidol in the treatment of schizophrenia. Sertindole Study Group. The American journal of psychiatry, 1997, Volume: 154, Issue:6 Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Basal Ganglia Diseases; Chronic Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Dyskinesia, Drug-Induced; Female; Haloperidol; Hospitalization; Humans; Imidazoles; Indoles; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenia, Paranoid; Schizophrenic Psychology; Treatment Outcome	1997
Long-term efficacy and safety comparison of sertindole and haloperidol in the treatment of schizophrenia. The Sertindole Study Group. Psychopharmacology bulletin, 1998, Volume: 34, Issue:1 Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Double-Blind Method; Female; Haloperidol; Humans; Imidazoles; Indoles; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia	1998
Novel antipsychotics: comparison of weight gain liabilities. The Journal of clinical psychiatry, 1999, Volume: 60, Issue:6 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Double-Blind Method; Haloperidol; Humans; Imidazoles; Indoles; Male; Obesity; Olanzapine; Pirenzepine; Placebos; Retrospective Studies; Risperidone; Schizophrenia; Weight Gain	1999
Course of recovery of cognitive impairment in patients with schizophrenia: a randomised double-blind study comparing sertindole and haloperidol. Pharmacopsychiatry, 2007, Volume: 40, Issue:6 Topics: Adolescent; Adult; Antipsychotic Agents; Cognition Disorders; Discrimination, Psychological; Double-Blind Method; Female; Haloperidol; Humans; Imidazoles; Indoles; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Psychomotor Performance; Reaction Time; Schizophrenia; Schizophrenic Psychology	2007
FDG-PET and MRI imaging of the effects of sertindole and haloperidol in the prefrontal lobe in schizophrenia. Schizophrenia research, 2009, Volume: 114, Issue:1-3 Topics: Adult; Analysis of Variance; Antipsychotic Agents; Brain Mapping; Female; Fluorodeoxyglucose F18; Frontal Lobe; Haloperidol; Humans; Imidazoles; Indoles; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Positron-Emission Tomography; Psychiatric Status Rating Scales; Schizophrenia; Young Adult	2009
Dose-response relationship of sertindole and haloperidol using the pharmacopsychometric triangle. Acta psychiatrica Scandinavica, 2011, Volume: 123, Issue:2 Topics: Antipsychotic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Haloperidol; Humans; Imidazoles; Indoles; Psychiatric Status Rating Scales; Psychometrics; Schizophrenia	2011
A double-blind, randomized study comparing the efficacy and safety of sertindole and risperidone in patients with treatment-resistant schizophrenia. The Journal of clinical psychiatry, 2011, Volume: 72, Issue:2 Topics: Adult; Antipsychotic Agents; Double-Blind Method; Drug Resistance; Drug-Related Side Effects and Adverse Reactions; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Imidazoles; Indoles; Male; Middle Aged; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome	2011
Sertindole in the long-term treatment of schizophrenia. International clinical psychopharmacology, 2012, Volume: 27, Issue:4 Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Female; Haloperidol; Humans; Imidazoles; Indoles; Maintenance Chemotherapy; Male; Middle Aged; Patient Dropouts; Psychiatric Status Rating Scales; Schizophrenia	2012

Other Studies

44 other study(ies) available for sertindole and haloperidol

Article	Year
Noncataleptogenic, centrally acting dopamine D-2 and serotonin 5-HT2 antagonists within a series of 3-substituted 1-(4-fluorophenyl)-1H-indoles. Journal of medicinal chemistry, 1992, Mar-20, Volume: 35, Issue:6 Topics: Animals; Antipsychotic Agents; Dopamine Antagonists; Imidazoles; Indoles; Male; Mice; Piperazines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship	1992
Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding. Psychopharmacology, 1996, Volume: 124, Issue:1-2 Topics: Animals; Antipsychotic Agents; Brain; Cells, Cultured; Clozapine; Haloperidol; Humans; Male; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Serotonin; Risperidone	1996
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study. European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3 Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes	1998
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers. Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18 Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2002
Synthesis and structure-affinity relationship investigations of 5-heteroaryl-substituted analogues of the antipsychotic sertindole. A new class of highly selective alpha(1) adrenoceptor antagonists. Journal of medicinal chemistry, 2003, Jan-16, Volume: 46, Issue:2 Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Azoles; Brain; Cell Line; Cricetinae; Humans; Imidazoles; In Vitro Techniques; Indoles; Pyridines; Pyrimidines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship; Triazoles	2003
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:3 Topics: Animals; Antipsychotic Agents; Discriminant Analysis; Drug Evaluation, Preclinical; Forecasting; Humans; Protein Binding; Receptors, Histamine H1; Statistics, Nonparametric; Weight Gain	2003
Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches. Bioorganic & medicinal chemistry letters, 2003, May-19, Volume: 13, Issue:10 Topics: Amino Acids, Aromatic; Cation Transport Proteins; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Imidazoles; Indoles; Inhibitory Concentration 50; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship; Structural Homology, Protein; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG	2003
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
A two-state homology model of the hERG K+ channel: application to ligand binding. Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation	2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers. European journal of medicinal chemistry, 2009, Volume: 44, Issue:5 Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship	2009
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers. Journal of medicinal chemistry, 2009, Jul-23, Volume: 52, Issue:14 Topics: Binding Sites; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Potassium Channel Blockers; Protein Binding; Protein Conformation	2009
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection	2011
MICE models: superior to the HERG model in predicting Torsade de Pointes. Scientific reports, 2013, Volume: 3 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia. Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11 Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Avoidance Learning; Benzoxazoles; Catalepsy; CHO Cells; Cricetulus; Dementia; Dopamine D2 Receptor Antagonists; HEK293 Cells; Humans; Male; Models, Molecular; Motor Activity; Radioligand Assay; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides	2014
Electrophysiological profile of the new atypical neuroleptic, sertindole, on midbrain dopamine neurones in rats: acute and repeated treatment. Synapse (New York, N.Y.), 1992, Volume: 10, Issue:1 Topics: Animals; Antipsychotic Agents; Apomorphine; Clozapine; Dextroamphetamine; Dopamine; Drug Administration Schedule; Electrophysiology; Haloperidol; Imidazoles; Indoles; Male; Mesencephalon; Neurons; Rats; Rats, Inbred Strains; Substantia Nigra; Tegmentum Mesencephali	1992
Differential effects of classical and newer antipsychotics on the hypermotility induced by two dose levels of D-amphetamine. European journal of pharmacology, 1995, Sep-05, Volume: 283, Issue:1-3 Topics: Animals; Antipsychotic Agents; Clozapine; Dextroamphetamine; Dose-Response Relationship, Drug; Fluphenazine; Haloperidol; Imidazoles; Indoles; Locomotion; Male; Motor Activity; Prazosin; Rats; Rats, Wistar; Ritanserin	1995
Sertindole antagonizes morphine-, cocaine-, and methamphetamine-induced place preference in the rat. Life sciences, 1995, Volume: 57, Issue:13 Topics: Animals; Antipsychotic Agents; Cocaine; Conditioning, Operant; Fluphenazine; Haloperidol; Imidazoles; Indoles; Male; Methamphetamine; Morphine; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reward; Spatial Behavior	1995
Comparison of short-term administration of sertindole, clozapine and haloperidol on the inactivation of midbrain dopamine neurons in the rat. European journal of pharmacology, 1994, Mar-21, Volume: 254, Issue:3 Topics: Animals; Antipsychotic Agents; Clozapine; Haloperidol; Imidazoles; Indoles; Male; Rats; Rats, Wistar; Substantia Nigra; Ventral Tegmental Area	1994
Behavioral effects of sertindole, risperidone, clozapine and haloperidol in Cebus monkeys. Psychopharmacology, 1996, Volume: 124, Issue:1-2 Topics: Animals; Antipsychotic Agents; Behavior, Animal; Cebus; Clozapine; Dose-Response Relationship, Drug; Haloperidol; Imidazoles; Indoles; Risperidone	1996
A naturalistic pilot study comparing haloperidol, clozapine, sertindole, and risperidone in partially responsive chronic schizophrenia or schizoaffective disorder. Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:6 Topics: Adult; Antipsychotic Agents; Clozapine; Female; Haloperidol; Humans; Imidazoles; Indoles; Male; Psychotic Disorders; Risperidone; Schizophrenia; Treatment Failure	1997
Sertindole and dopamine D2 receptor occupancy in comparison to risperidone, clozapine and haloperidol - a 123I-IBZM SPECT study. Psychopharmacology, 1998, Volume: 136, Issue:4 Topics: Adult; Antipsychotic Agents; Benzamides; Clozapine; Female; Haloperidol; Humans; Imidazoles; Indoles; Iodine Radioisotopes; Male; Middle Aged; Neostriatum; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1998
Sertindole versus haloperidol for schizophrenia. The American journal of psychiatry, 1998, Volume: 155, Issue:9 Topics: Antipsychotic Agents; Haloperidol; Humans; Imidazoles; Indoles; Patient Dropouts; Randomized Controlled Trials as Topic; Research Design; Schizophrenia	1998
Sertindole versus haloperidol for schizophrenia. The American journal of psychiatry, 1998, Volume: 155, Issue:9 Topics: Antipsychotic Agents; Haloperidol; Humans; Imidazoles; Indoles; Randomized Controlled Trials as Topic; Research Design; Schizophrenia; Schizophrenic Psychology	1998
Chronic olanzapine or sertindole treatment results in reduced oral chewing movements in rats compared to haloperidol. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1998, Volume: 19, Issue:5 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Dyskinesia, Drug-Induced; Haloperidol; Imidazoles; Indoles; Male; Mastication; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley	1998
Some, but not all, antipsychotic drugs potentiate a low level of prepulse inhibition shown by rats of the Wistar strain. Behavioural pharmacology, 1997, Volume: 8, Issue:4 Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Behavior, Animal; Benzazepines; Benzodiazepines; Clozapine; Haloperidol; Imidazoles; Indoles; Injections, Intraperitoneal; Male; Neural Inhibition; Olanzapine; Pirenzepine; Prazosin; Rats; Rats, Wistar; Reflex, Startle; Remoxipride; Risperidone; Ritanserin; Serotonin Antagonists	1997
Prolongation of QT interval in isolated feline hearts by antipsychotic drugs. Journal of clinical psychopharmacology, 1998, Volume: 18, Issue:6 Topics: Analysis of Variance; Animals; Antipsychotic Agents; Cats; Clozapine; Electrocardiography; Haloperidol; Heart; Humans; Imidazoles; In Vitro Techniques; Indoles; Risperidone	1998
Traditional and new antipsychotic drugs differentially alter neurotransmission markers in basal ganglia-thalamocortical neural pathways. Synapse (New York, N.Y.), 2001, Volume: 39, Issue:2 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Corpus Striatum; Down-Regulation; Haloperidol; Imidazoles; Indoles; Male; Neurotransmitter Agents; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Thalamus; Up-Regulation	2001
Effects of acute versus chronic treatment with typical or atypical antipsychotics on d-amphetamine-induced sensorimotor gating deficits in rats. Psychopharmacology, 2001, Volume: 156, Issue:2-3 Topics: Acoustic Stimulation; Animals; Antipsychotic Agents; Benzodiazepines; Central Nervous System Stimulants; Dextroamphetamine; Haloperidol; Hyperkinesis; Imidazoles; Indoles; Male; Olanzapine; Pirenzepine; Rats; Rats, Wistar; Receptors, Dopamine; Reflex, Startle; Time Factors	2001
Effects of antipsychotic drugs on operant responding after acute and repeated administration. Psychopharmacology, 2002, Volume: 160, Issue:2 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Conditioning, Operant; Dibenzothiazepines; Dose-Response Relationship, Drug; Haloperidol; Imidazoles; Indoles; Male; Olanzapine; Pirenzepine; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Remoxipride; Risperidone; Thioridazine; Time Factors	2002
Treatment with the new antipsychotic sertindole for late-occurring undesirable movement effects. International clinical psychopharmacology, 2005, Volume: 20, Issue:6 Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Clopenthixol; Female; Haloperidol; Humans; Imidazoles; Indoles; Male; Middle Aged; Schizophrenia; Time Factors	2005
Comparing sertindole to other new generation antipsychotics on preferential dopamine output in limbic versus striatal projection regions: mechanism of action. Synapse (New York, N.Y.), 2006, Dec-01, Volume: 60, Issue:7 Topics: Animals; Antipsychotic Agents; Clozapine; Corpus Striatum; Dopamine; Dopamine Agents; Efferent Pathways; Haloperidol; Imidazoles; Indoles; Limbic System; Male; Presynaptic Terminals; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Agents; Synaptic Transmission	2006
Reversal of PCP-induced learning and memory deficits in the Morris' water maze by sertindole and other antipsychotics. Psychopharmacology, 2007, Volume: 193, Issue:2 Topics: Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Haloperidol; Imidazoles; Indoles; Male; Maze Learning; Phencyclidine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Risperidone; Schizophrenic Psychology	2007
Status epilepticus associated with sertindole. European journal of neurology, 2007, Volume: 14, Issue:8 Topics: Anticonvulsants; Antipsychotic Agents; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Electroencephalography; Female; Haloperidol; Humans; Imidazoles; Indoles; Middle Aged; Phenytoin; Receptor, Serotonin, 5-HT2C; Schizophrenia; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Status Epilepticus; Treatment Outcome	2007
Dopamine D2(High) receptors moderately elevated by sertindole. Synapse (New York, N.Y.), 2008, Volume: 62, Issue:5 Topics: Animals; Antipsychotic Agents; Binding, Competitive; Domperidone; Dopamine Antagonists; Guanine Nucleotides; Haloperidol; Imidazoles; Indoles; Neostriatum; Oxazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2	2008
Using pharmacokinetic-pharmacodynamic modelling as a tool for prediction of therapeutic effective plasma levels of antipsychotics. European journal of pharmacology, 2008, Apr-28, Volume: 584, Issue:2-3 Topics: Administration, Oral; Animals; Antipsychotic Agents; Basal Ganglia; Behavior, Animal; Benzodiazepines; Binding, Competitive; Clozapine; Conditioning, Psychological; Dopamine Antagonists; Haloperidol; Imidazoles; Indoles; Injections, Subcutaneous; Male; Models, Biological; Olanzapine; Protein Binding; Raclopride; Rats; Rats, Wistar; Receptors, Dopamine D2; Reproducibility of Results; Risperidone	2008
Comparison of haloperidol, risperidone, sertindole, and modafinil to reverse an attentional set-shifting impairment following subchronic PCP administration in the rat--a back translational study. Psychopharmacology, 2009, Volume: 202, Issue:1-3 Topics: Animals; Antipsychotic Agents; Attention; Benzhydryl Compounds; Central Nervous System Stimulants; Cognition Disorders; Conditioning, Operant; Discrimination, Psychological; Excitatory Amino Acid Antagonists; Haloperidol; Imidazoles; Indoles; Male; Modafinil; Phencyclidine; Psychomotor Performance; Rats; Risperidone; Schizophrenic Psychology	2009
The antagonistic effect of antipsychotic drugs on a HEK293 cell line stably expressing human alpha1A1-adrenoceptors. European journal of pharmacology, 2008, Oct-31, Volume: 596, Issue:1-3 Topics: Adrenergic alpha-1 Receptor Antagonists; Antipsychotic Agents; Arteries; Binding, Competitive; Calcium; Cell Line; Haloperidol; Humans; Imidazoles; Indoles; Phenylephrine; Prazosin; Protein Isoforms; Radioligand Assay; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Risperidone; Skin; Tritium; Vascular Resistance	2008
Effect of sertindole on extracellular dopamine, acetylcholine, and glutamate in the medial prefrontal cortex of conscious rats: a comparison with risperidone and exploration of mechanisms involved. Psychopharmacology, 2009, Volume: 206, Issue:1 Topics: Acetylcholine; Animals; Antipsychotic Agents; Dopamine; Dopamine D2 Receptor Antagonists; Drug Synergism; Extracellular Space; Fluorobenzenes; Glutamic Acid; Haloperidol; Imidazoles; Indoles; Male; Microdialysis; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin 5-HT2 Receptor Antagonists	2009
Divergent acute and chronic modulation of glutamatergic postsynaptic density genes expression by the antipsychotics haloperidol and sertindole. Psychopharmacology, 2010, Volume: 212, Issue:3 Topics: Animals; Antipsychotic Agents; Carrier Proteins; Cytoskeletal Proteins; Gene Expression Regulation; Haloperidol; Homer Scaffolding Proteins; Imidazoles; Indoles; Male; Nerve Tissue Proteins; Post-Synaptic Density; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Time Factors	2010
A pharmacoeconomic analysis of sertindole in the treatment of schizophrenia in Sweden. Nordic journal of psychiatry, 2011, Volume: 65, Issue:6 Topics: Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Cost-Benefit Analysis; Economics, Pharmaceutical; Female; Haloperidol; Humans; Imidazoles; Indoles; Male; Models, Economic; National Health Programs; Olanzapine; Piperazines; Quinolones; Risperidone; Schizophrenia; Sweden	2011