serine and transforming growth factor beta

serine has been researched along with transforming growth factor beta in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	19 (27.54)	18.2507
2000's	24 (34.78)	29.6817
2010's	18 (26.09)	24.3611
2020's	8 (11.59)	2.80

Authors

Authors	Studies
Greenberg, AH; Hurta, RA; Khalil, N; Kondaiah, P; Samuel, SK; Turley, EA; Wright, JA	1
Attisano, L; Cárcamo, J; Doody, J; Laiho, M; Massagué, J; Wang, XF; Wrana, JL; Zentella, A	1
Asplund, T; Heldin, P; Laurent, TC; Thelin, S; Ytterberg, D	1
Berenson, GS; Ciolino, HP; Vijayagopal, P	1
Bickenbach, JR; Bundman, D; Krieg, T; Longley, MA; Roberts, AB; Roche, NS; Roop, DR; Rothnagel, JA; Sellheyer, K	1
Factor, V; Kondaiah, P; Kopp, J; Nagy, P; Roberts, AB; Sanderson, N; Sporn, MB; Thorgeirsson, SS; Wakefield, L	1
Franzén, P; Heldin, CH; Miyazono, K	1
Amatayakul-Chantler, S; Böttinger, EP; Gakenheimer, K; Qian, SW; Roberts, AB; Sporn, MB	1
Fontanière, B; Frébourg, T; Fröschl, G; Michot, JP; Morel, AP; Oberhammer, F; Ozturk, M; Ponchel, F; Puisieux, A; Tabone, E	1
Amagasa, T; Ichijo, H; Miyazono, K; Nishitoh, H; Saitoh, M; Takagi, M	1
de Caestecker, MP; Dehejia, A; Lechleider, RJ; Polymeropoulos, MH; Roberts, AB	1
Heldin, CH; Miyazono, K; Souchelnytskyi, S; ten Dijke, P	1
Doody, J; Hata, A; Kretzschmar, M; Liu, F; Massagué, J	1
Engström, U; Heldin, CH; Souchelnytskyi, S; Tamaki, K; ten Dijke, P; Wernstedt, C	1
Doré, JJ; Edens, M; Garamszegi, N; Leof, EB	1
Hu, X; Moscinski, LC; Zuckerman, KS	1
Cattamanchi, A; Ernst, JD; Kim, AC; Ting, LM	1
de Caestecker, MP; Poncelet, AC; Schnaper, HW	1
Kelly, D; Kingsley-Kallesen, ML; Rizzino, A	1
Abdel-Wahab, N; Chantry, A; Lui, S; Mason, RM; Wicks, SJ	1
Cress, WD; Hu, X; Zhong, Q; Zuckerman, KS	1
Heldin, CH; Landström, M; Pulaski, L; Souchelnytskyi, S	1
Chang, NS	1
Abdel-Wahab, N; Chantry, A; Mason, RM; Wicks, SJ	1
Britto, JA; Evans, RD; Hayward, RD; Jones, BM	1
Ewton, DZ; Friedman, E; Jin, K; Kim, GY; Mercer, SE; Yan, Z	1
McKeown-Longo, PJ; Zheng, M	1
Decaestecker, M; Hayashida, T; Schnaper, HW	1
Sanders, PW; Ying, WZ	1
Ma, DZ; Su, JM; Wang, LY; Xu, Z; Zha, XL	1
Dubinett, SM; Huang, M; Keane, MP; Rozengurt, E; Sharma, S; Strieter, RM; Zhang, L; Zhu, LX	1
Ambrosio, S; Bartrons, R; Reiriz, J; Rosa, JL; Ventura, F; Viñals, F	1
He, D; Liu, F; Long, J; Matsuura, I; Wang, G	1
Aspenström, P; Edlund, S; Grimsby, S; Heldin, CH; Landström, M; Lee, SY; Zhang, S	1
Beight, D; Brooks, HB; Herron, DK; Jones, ML; Lampe, JW; McMillen, WT; Mort, N; Peng, SB; Sawyer, JS; Watkins, SA; Xia, X; Yan, L; Yingling, JM	1
Sebti, SM; Wang, DA	1
Matsuzaki, K	1
Goldberger, O; Hayashida, K; Johnston, DR; Park, PW	1
Amini Nik, S; Cassiman, JJ; Ebrahim, RP; Tejpar, S; Van Dam, K	1
Bord, E; Hamada, H; Kishore, R; Lambers, E; Losordo, DW; Qin, G; Rajasingh, J	1
Balogh, I; Berta, A; Fazakas, F; Losonczy, G; Matesz, K; Sohajda, Z; Takács, L; Tóth, K; Vereb, G	1
Atanasoski, S; Grabner, H; Jacob, C; Suter, U	1
André, J; Bernuau, D; Daniel, F; Güller, MC; Legrand, A; Mauviel, A; Setterblad, N; Verrecchia, F	1
Bogyo, M	1
Isogaya, K; Miyazawa, K; Miyazono, K; Nagata, M; Nagata, S; Saitoh, M; Yuki, K	1
Ceccarelli, DF; David, L; Ogunjimi, AA; Sicheri, F; Wrana, JL; Zeqiraj, E	1
Chen, YG; Sun, Q; Traugh, JA; Tuazon, PT; Wu, X; Yan, X; Zhang, J	1
Abel, B; Cooper, L; Jang, S; Sowa, G; Vo-Ransdell, C; Willoughby, C; Xie, L	1
Almeida, JC; Alves-Leon, SV; Castro, NG; de Miranda, J; de Souza, JM; Diniz, LP; Gomes, FC; Kahn, SA; Panizzutti, R; Romão, LF; Setti-Perdigão, P; Stipursky, J; Tortelli, V; Vargas Lopes, C	1
Jin, Q; Mulder, KM; Zhong, Y	1
Burch, ML; Febbraio, MA; Getachew, R; Little, PJ; Osman, N	1
Bera, A; Choudhury, GG; Das, F; Ghosh-Choudhury, N; Kasinath, BS	1
Browne, JA; Hayashida, T; Liu, X; Schnaper, HW	1
Bergh, A; Fu, JY; Gudey, SK; Heldin, CH; Landström, M; Marcusson, A; Thakur, N	1
Ha, H; Manoharan, R; Seong, HA	1
Campbell, DG; Cozza, G; Gourlay, R; Herhaus, L; Perez-Oliva, AB; Pinna, LA; Sapkota, GP; Weidlich, S	1
Brown, AS; Howe, PH; Mohanty, BK	1
Azuma, M; Baba, Y; Koyasu, S; Kurebayashi, Y; Minowa, A; Nadya, NA; Nagai, S; Yoshimura, A	1
Bonham, C; Chandel, NS; Cho, T; Dulin, NO; Hamanaka, RB; Husain, AN; Meliton, AY; Mutlu, GM; Nigdelioglu, R; O'Leary, E; Sun, K; Witt, LJ; Wolfgeher, D; Woods, PS; Wu, D	1
Ansbro, B; Ard, S; Dulin, NO; Guzy, RD; Hamanaka, RB; Meliton, AY; Mutlu, GM; Nigdelioglu, R; O'Leary, E; Rohde, JM; Sun, KA; Tian, Y; Witt, LJ; Woods, PS; Wu, D	1
Bae, HS; Baek, JH; Islam, R; Kim, BS; Lee, YS; Ryoo, HM; Shin, HR; Woo, KM; Yoon, H; Yoon, WJ	1
Gregg, BS; Kimmel, L; Nyati, MK; Nyati, S; Ray, D; Rehemtulla, A; Speers, C; Xu, J; Young, G	1
Cetin-Atalay, R; Gökalp, GA; Hamanaka, RB; Kimmig, LM; Meliton, AY; Mutlu, GM; Nigdelioglu, R; O'Leary, EM; Sun, KA; Tian, Y; Witt, LJ; Woods, PS	1
Cho, JW; Ji, S; Kang, MJ; Kim, E; Kim, YJ; Kweon, TH; Park, YS; Yang, WH; Yi, EC	1
Jimenez, SA; Mendoza, FA	1
Dai, J; Hong, Y; Hu, Y; Jiang, P; Li, R; Liu, D; Lv, H; Song, M; Wang, H; Wang, Z; Yao, S; Zhang, X; Zhao, G; Zhou, Z	1
Choi, JH; Hwang, YE; Jeong, J; Keum, S; Lee, J; Rhee, S; You, E	1
Burke, JP; Duggan, WP; O'Connell, E; Prehn, JHM	1
Cai, J; Dong, Z; Liu, Y; Tang, C; Wang, T; Zhou, Y	1

Reviews

3 review(s) available for serine and transforming growth factor beta

Article	Year
Smad3 phosphoisoform-mediated signaling during sporadic human colorectal carcinogenesis. Histology and histopathology, 2006, Volume: 21, Issue:6 Topics: Adenocarcinoma; Adenoma; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neoplasms; Disease Progression; Humans; MAP Kinase Kinase 4; Neoplasm Invasiveness; Phosphorylation; Protein Isoforms; Serine; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta; Tumor Cells, Cultured	2006
Serine/threonine kinase inhibition as antifibrotic therapy: transforming growth factor-β and Rho kinase inhibitors. Rheumatology (Oxford, England), 2022, 04-11, Volume: 61, Issue:4 Topics: Fibrosis; Humans; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; rho-Associated Kinases; Serine; Threonine; Transforming Growth Factor beta; Transforming Growth Factors	2022
Serine-Arginine Protein Kinase 1 (SRPK1): a systematic review of its multimodal role in oncogenesis. Molecular and cellular biochemistry, 2022, Volume: 477, Issue:10 Topics: Arginine; Arginine Kinase; Carcinogenesis; Cell Transformation, Neoplastic; Humans; Neoplasms; NF-kappa B; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; RNA Splicing Factors; Serine; Transforming Growth Factor beta	2022

Other Studies

66 other study(ies) available for serine and transforming growth factor beta

Article	Year
Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-beta 1 (Ser223, 225). The EMBO journal, 1992, Volume: 11, Issue:4 Topics: Amino Acid Sequence; Animals; Cathepsin L; Cathepsins; Cell Line; Cell Movement; Enzyme Precursors; Genes, ras; Genetic Vectors; Kinetics; Metallothionein; Mice; Microbial Collagenase; Models, Biological; Mutagenesis, Site-Directed; Neoplasm Invasiveness; Plasmids; Promoter Regions, Genetic; RNA, Messenger; Serine; Sulfates; Transfection; Transforming Growth Factor beta; Zinc; Zinc Sulfate	1992
TGF beta signals through a heteromeric protein kinase receptor complex. Cell, 1992, Dec-11, Volume: 71, Issue:6 Topics: Amino Acid Sequence; Animals; Binding, Competitive; Cell Line; Mink; Models, Biological; Molecular Sequence Data; Multienzyme Complexes; Protein Kinases; Receptors, Cell Surface; Serine; Signal Transduction; Threonine; Transforming Growth Factor beta	1992
Characterization of the molecular mechanism involved in the activation of hyaluronan synthetase by platelet-derived growth factor in human mesothelial cells. The Biochemical journal, 1992, Apr-01, Volume: 283 ( Pt 1) Topics: Cell Membrane; Cells, Cultured; Cycloheximide; Enzyme Activation; Epithelial Cells; Epithelium; Glucuronosyltransferase; Glycosyltransferases; Humans; Hyaluronan Synthases; Kinetics; Membrane Proteins; Phosphorylation; Platelet-Derived Growth Factor; Protein Biosynthesis; Protein Kinase C; Serine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Threonine; Transferases; Transforming Growth Factor beta; Tyrosine; Vanadates; Xenopus Proteins	1992
Endothelial cell-conditioned medium modulates the synthesis and structure of proteoglycans in vascular smooth muscle cells. Biochimica et biophysica acta, 1992, Jun-10, Volume: 1135, Issue:2 Topics: Animals; Cattle; Chondroitin Sulfate Proteoglycans; Culture Media; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzymes; Glucosamine; Hot Temperature; Muscle, Smooth, Vascular; Serine; Sulfates; Time Factors; Transforming Growth Factor beta	1992
Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice. Proceedings of the National Academy of Sciences of the United States of America, 1993, Jun-01, Volume: 90, Issue:11 Topics: Amino Acid Sequence; Animals; Animals, Newborn; Cysteine; DNA; Gene Expression; Immunohistochemistry; Introns; Mice; Mice, Transgenic; Microscopy, Electron; Mutagenesis, Site-Directed; Reference Values; RNA; Serine; Skin; Swine; Transforming Growth Factor beta	1993
Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions. Proceedings of the National Academy of Sciences of the United States of America, 1995, Mar-28, Volume: 92, Issue:7 Topics: Animals; Apoptosis; Cell Division; Cells, Cultured; Codon; Crosses, Genetic; Cysteine; DNA, Complementary; Female; Gene Expression; Glomerulonephritis; Inflammation; Kidney; Liver; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Mitosis; Mutagenesis, Site-Directed; Myocardium; Restriction Mapping; Serine; Swine; Transforming Growth Factor beta	1995
The GS domain of the transforming growth factor-beta type I receptor is important in signal transduction. Biochemical and biophysical research communications, 1995, Feb-15, Volume: 207, Issue:2 Topics: Activin Receptors, Type I; Amino Acid Sequence; Animals; Cell Line; Chlorocebus aethiops; Cross-Linking Reagents; Glycine; Humans; Kidney; Lung; Mink; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Serine; Signal Transduction; Succinimides; Transcription, Genetic; Transfection; Transforming Growth Factor beta	1995
[Ser77]transforming growth factor-beta 1. Selective biological activity and receptor binding in mink lung epithelial cells. The Journal of biological chemistry, 1994, Nov-04, Volume: 269, Issue:44 Topics: Animals; Biological Assay; Cell Line; CHO Cells; Cricetinae; Cysteine; Disulfides; In Vitro Techniques; Mice; Mink; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Serine; Structure-Activity Relationship; Transforming Growth Factor beta	1994
Hepatocarcinoma-specific mutant p53-249ser induces mitotic activity but has no effect on transforming growth factor beta 1-mediated apoptosis. Cancer research, 1994, Apr-15, Volume: 54, Issue:8 Topics: Amino Acid Sequence; Animals; Apoptosis; Arginine; Base Sequence; Carcinoma, Hepatocellular; Cell Division; Cell Line; DNA Primers; Genes, p53; Humans; Liver Neoplasms; Mice; Mice, Nude; Mitosis; Mitotic Index; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Serine; Transfection; Transforming Growth Factor beta; Transplantation, Heterologous; Tumor Cells, Cultured	1994
Identification of important regions in the cytoplasmic juxtamembrane domain of type I receptor that separate signaling pathways of transforming growth factor-beta. The Journal of biological chemistry, 1996, Feb-02, Volume: 271, Issue:5 Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Division; Cells, Cultured; Cytoplasm; DNA Primers; Epithelial Cells; Epithelium; Lung; Mink; Molecular Sequence Data; Mutagenesis; Phosphorylation; Receptors, Transforming Growth Factor beta; Sequence Deletion; Sequence Homology, Amino Acid; Serine; Signal Transduction; Threonine; Transforming Growth Factor beta	1996
Serine phosphorylation, chromosomal localization, and transforming growth factor-beta signal transduction by human bsp-1. The Journal of biological chemistry, 1996, Jul-26, Volume: 271, Issue:30 Topics: Amino Acid Sequence; Base Sequence; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Chromosome Mapping; Chromosomes, Human, Pair 4; Cloning, Molecular; DNA-Binding Proteins; Humans; Molecular Sequence Data; Phosphorylation; Proteins; Repressor Proteins; Sequence Homology, Amino Acid; Serine; Signal Transduction; Smad Proteins; Trans-Activators; Transforming Growth Factor beta	1996
Phosphorylation of Ser165 in TGF-beta type I receptor modulates TGF-beta1-induced cellular responses. The EMBO journal, 1996, Nov-15, Volume: 15, Issue:22 Topics: Amino Acid Sequence; Animals; Apoptosis; Cell Division; COS Cells; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Molecular Sequence Data; Mutation; Peptide Mapping; Phosphopeptides; Phosphorylation; Phosphoserine; Receptors, Transforming Growth Factor beta; Serine; Signal Transduction; Transfection; Transforming Growth Factor beta	1996
The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase. Genes & development, 1997, Apr-15, Volume: 11, Issue:8 Topics: Activin Receptors; Activin Receptors, Type I; Amino Acid Sequence; Animals; Bone Morphogenetic Protein Receptors, Type I; Bone Morphogenetic Protein Receptors, Type II; Cell Line; Cell Nucleus; COS Cells; DNA-Binding Proteins; Epithelial Cells; Lung; Mink; Molecular Sequence Data; Mutation; Phosphopeptides; Phosphorylation; Protein Serine-Threonine Kinases; Receptors, Growth Factor; Serine; Signal Transduction; Smad Proteins; Smad2 Protein; Trans-Activators; Transforming Growth Factor beta	1997
Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling. The Journal of biological chemistry, 1997, Oct-31, Volume: 272, Issue:44 Topics: Amino Acid Sequence; Animals; Cell Line; COS Cells; DNA-Binding Proteins; Glutathione; Mink; Molecular Sequence Data; Mutagenesis; Peptide Mapping; Phosphorylation; Protein Binding; Recombinant Fusion Proteins; Serine; Signal Transduction; Smad2 Protein; Trans-Activators; Transforming Growth Factor beta	1997
Heteromeric and homomeric transforming growth factor-beta receptors show distinct signaling and endocytic responses in epithelial cells. The Journal of biological chemistry, 1998, Nov-27, Volume: 273, Issue:48 Topics: Activin Receptors, Type I; Amino Acid Substitution; Animals; Cell Division; Cell Line; Cell Membrane; Endocytosis; Epithelial Cells; Extracellular Matrix Proteins; Kinetics; Lung; Macromolecular Substances; Mink; Mutagenesis, Site-Directed; Point Mutation; Protein Multimerization; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins; Serine; Signal Transduction; Threonine; Transfection; Transforming Growth Factor beta	1998
Transforming growth factor beta inhibits growth of more differentiated myeloid leukemia cells and retinoblastoma protein phosphorylation at serine 795. Experimental hematology, 1999, Volume: 27, Issue:4 Topics: Cell Differentiation; Cell Division; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid; Phosphorylation; Proto-Oncogene Proteins; Retinoblastoma Protein; S Phase; Serine; Time Factors; Transforming Growth Factor beta; Tumor Cells, Cultured; Tumor Stem Cell Assay	1999
Mycobacterium tuberculosis inhibits IFN-gamma transcriptional responses without inhibiting activation of STAT1. Journal of immunology (Baltimore, Md. : 1950), 1999, Oct-01, Volume: 163, Issue:7 Topics: Animals; Antibodies, Monoclonal; Biological Transport; Cell Nucleus; Cells, Cultured; CREB-Binding Protein; DNA-Binding Proteins; Humans; Interferon-gamma; Interferon-Stimulated Gene Factor 3; Macrophages; Mycobacterium tuberculosis; Nuclear Proteins; Phosphorylation; Receptors, IgG; RNA, Messenger; Serine; Signal Transduction; STAT1 Transcription Factor; Subcellular Fractions; Toxoplasma; Trans-Activators; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transforming Growth Factor beta; Tyrosine	1999
The transforming growth factor-beta/SMAD signaling pathway is present and functional in human mesangial cells. Kidney international, 1999, Volume: 56, Issue:4 Topics: Blotting, Northern; Blotting, Western; Cells, Cultured; Collagen; DNA-Binding Proteins; Extracellular Matrix Proteins; Gene Expression Regulation; Genes, Reporter; Glomerular Mesangium; Humans; Luciferases; Mutagenesis; Phosphorylation; Promoter Regions, Genetic; RNA, Messenger; Serine; Signal Transduction; Smad2 Protein; Smad3 Protein; Smad4 Protein; Trans-Activators; Transcription, Genetic; Transfection; Transforming Growth Factor beta	1999
Transcriptional regulation of the transforming growth factor-beta2 promoter by cAMP-responsive element-binding protein (CREB) and activating transcription factor-1 (ATF-1) is modulated by protein kinases and the coactivators p300 and CREB-binding protein. The Journal of biological chemistry, 1999, Nov-26, Volume: 274, Issue:48 Topics: Activating Transcription Factor 1; Animals; Base Sequence; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Catalytic Domain; Cell Differentiation; Cell Nucleus; CREB-Binding Protein; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation; Mitogen-Activated Protein Kinases; Nuclear Proteins; Phosphorylation; Promoter Regions, Genetic; Protein Kinases; Recombinant Fusion Proteins; Serine; Trans-Activators; Transcription Factors; Transcription, Genetic; Transfection; Transforming Growth Factor beta; Tumor Cells, Cultured; Upstream Stimulatory Factors	1999
Inactivation of smad-transforming growth factor beta signaling by Ca(2+)-calmodulin-dependent protein kinase II. Molecular and cellular biology, 2000, Volume: 20, Issue:21 Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Nucleus; Chromatography, Thin Layer; COS Cells; Cytoplasm; DNA-Binding Proteins; Glutathione Transferase; Humans; Immunoblotting; Luciferases; Microscopy, Fluorescence; Models, Genetic; Phosphorylation; Precipitin Tests; Receptor, ErbB-2; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Serine; Signal Transduction; Smad2 Protein; Smad3 Protein; Smad4 Protein; Thapsigargin; Trans-Activators; Transcription, Genetic; Transfection; Transforming Growth Factor beta	2000
Transforming growth factor beta inhibits the phosphorylation of pRB at multiple serine/threonine sites and differentially regulates the formation of pRB family-E2F complexes in human myeloid leukemia cells. Biochemical and biophysical research communications, 2000, Oct-05, Volume: 276, Issue:3 Topics: Blotting, Western; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line; DNA; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; E2F3 Transcription Factor; E2F4 Transcription Factor; Gene Expression Regulation; Humans; Leukemia, Myeloid; Macromolecular Substances; Myeloid Cells; Nuclear Proteins; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Proteins; Retinoblastoma Protein; Retinoblastoma-Binding Protein 1; Retinoblastoma-Like Protein p107; Retinoblastoma-Like Protein p130; Serine; Threonine; Time Factors; Transcription Factor DP1; Transcription Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured	2000
Phosphorylation of Smad7 at Ser-249 does not interfere with its inhibitory role in transforming growth factor-beta-dependent signaling but affects Smad7-dependent transcriptional activation. The Journal of biological chemistry, 2001, Apr-27, Volume: 276, Issue:17 Topics: 3T3 Cells; Amino Acid Sequence; Animals; Aspartic Acid; Bone Morphogenetic Proteins; Cell Nucleus; COS Cells; DNA; DNA-Binding Proteins; Genes, Reporter; Ligands; Luciferases; Mice; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Phosphorylation; Promoter Regions, Genetic; Protein Structure, Tertiary; Serine; Signal Transduction; Smad7 Protein; Time Factors; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Transfection; Transforming Growth Factor beta	2001
The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression. The Journal of biological chemistry, 2002, Mar-22, Volume: 277, Issue:12 Topics: Animals; Ankyrins; Apoptosis; Cell Division; Cell Line; Cell Nucleus; COS Cells; Cytosol; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Etoposide; Genes, Dominant; Humans; Hyaluronoglucosaminidase; Hypoxia; I-kappa B Proteins; Liver; Mice; Microscopy, Fluorescence; Mutagenesis, Site-Directed; NF-KappaB Inhibitor alpha; Phosphorylation; Precipitin Tests; Proline; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Proteins; Serine; Spleen; Staurosporine; Threonine; Time Factors; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ultraviolet Rays	2002
Decorin suppresses transforming growth factor-beta-induced expression of plasminogen activator inhibitor-1 in human mesangial cells through a mechanism that involves Ca2+-dependent phosphorylation of Smad2 at serine-240. The Biochemical journal, 2002, Mar-15, Volume: 362, Issue:Pt 3 Topics: Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Transformed; Decorin; DNA Primers; DNA-Binding Proteins; Enzyme Inhibitors; Extracellular Matrix Proteins; Gene Expression Regulation; Genes, Reporter; Glomerular Mesangium; Humans; Luciferases; Phosphorylation; Plasminogen Activator Inhibitor 1; Protein Kinase Inhibitors; Proteoglycans; Reverse Transcriptase Polymerase Chain Reaction; Serine; Smad2 Protein; Sulfonamides; Trans-Activators; Transfection; Transforming Growth Factor beta	2002
Toward pathogenesis of Apert cleft palate: FGF, FGFR, and TGF beta genes are differentially expressed in sequential stages of human palatal shelf fusion. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2002, Volume: 39, Issue:3 Topics: Acrocephalosyndactylia; Apoptosis; Cleft Palate; DNA-Binding Proteins; Epithelium; Exons; Fibroblast Growth Factor 2; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; In Situ Hybridization; Keratinocytes; Mesoderm; Mutation; Palate; Protein Isoforms; Receptors, Fibroblast Growth Factor; Serine; Signal Transduction; STAT1 Transcription Factor; Trans-Activators; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta3; Tryptophan; Up-Regulation	2002
The stress-activated protein kinases p38 alpha and JNK1 stabilize p21(Cip1) by phosphorylation. The Journal of biological chemistry, 2002, Aug-16, Volume: 277, Issue:33 Topics: Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Imidazoles; Mitogen-Activated Protein Kinase 14; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Serine; Signal Transduction; Threonine; Transforming Growth Factor beta; Tumor Cells, Cultured; Up-Regulation	2002
Regulation of HEF1 expression and phosphorylation by TGF-beta 1 and cell adhesion. The Journal of biological chemistry, 2002, Oct-18, Volume: 277, Issue:42 Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Catalysis; Cell Adhesion; Cell Division; Cell Line; Cells, Cultured; Cytochalasin D; Cytoskeleton; Dactinomycin; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Humans; Immunoblotting; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Serine; Signal Transduction; Substrate Specificity; Thiazoles; Thiazolidines; Threonine; Time Factors; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine; Up-Regulation	2002
Cross-talk between ERK MAP kinase and Smad signaling pathways enhances TGF-beta-dependent responses in human mesangial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:11 Topics: Animals; Cell Line; Cells, Cultured; Collagen; DNA-Binding Proteins; Enzyme Inhibitors; Glomerular Mesangium; Humans; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Models, Biological; Phosphorylation; Promoter Regions, Genetic; Serine; Signal Transduction; Smad2 Protein; Smad3 Protein; Trans-Activators; Transcriptional Activation; Transforming Growth Factor beta; Transforming Growth Factor beta1	2003
The interrelationship between TGF-beta1 and nitric oxide is altered in salt-sensitive hypertension. American journal of physiology. Renal physiology, 2003, Volume: 285, Issue:5 Topics: Animals; Aorta; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitrates; Nitric Oxide; Nitrites; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Inbred Dahl; Serine; Sodium Chloride, Dietary; Transforming Growth Factor beta; Transforming Growth Factor beta1	2003
Transforming growth factor-beta1 stimulated protein kinase B serine-473 and focal adhesion kinase tyrosine phosphorylation dependent on cell adhesion in human hepatocellular carcinoma SMMC-7721 cells. Biochemical and biophysical research communications, 2003, Dec-12, Volume: 312, Issue:2 Topics: Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Dose-Response Relationship, Drug; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Liver Neoplasms; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine	2003
Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis. The Journal of biological chemistry, 2004, Jul-02, Volume: 279, Issue:27 Topics: Blotting, Northern; Blotting, Western; Cell Line, Tumor; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type III; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix; Fibroblasts; Fibrosis; Humans; Interleukin-7; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; RNA, Small Interfering; Serine; Signal Transduction; Threonine; Transforming Growth Factor beta; Up-Regulation	2004
BMP-2 decreases Mash1 stability by increasing Id1 expression. The EMBO journal, 2004, Sep-01, Volume: 23, Issue:17 Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Casein Kinase II; Cell Line, Tumor; DNA-Binding Proteins; Drug Stability; Humans; In Vitro Techniques; Inhibitor of Differentiation Protein 1; Mice; Models, Biological; Neurosecretory Systems; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Proteins; Repressor Proteins; RNA Processing, Post-Transcriptional; Serine; Signal Transduction; TCF Transcription Factors; Transcription Factor 7-Like 1 Protein; Transcription Factors; Transforming Growth Factor beta	2004
The Smad3 linker region contains a transcriptional activation domain. The Biochemical journal, 2005, Feb-15, Volume: 386, Issue:Pt 1 Topics: Adenovirus E1A Proteins; Animals; Binding Sites; Cells, Cultured; DNA; DNA-Binding Proteins; Genes, Reporter; Humans; Mammals; Nuclear Proteins; Proline; Protein Binding; Protein Interaction Mapping; Protein Structure, Tertiary; Recombinant Fusion Proteins; Serine; Smad3 Protein; Structure-Activity Relationship; Trans-Activators; Transcriptional Activation; Transfection; Transforming Growth Factor beta	2005
Interaction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosis. Molecular and cellular biology, 2005, Volume: 25, Issue:4 Topics: Animals; Apoptosis; beta Catenin; Cell Fractionation; Chlorocebus aethiops; COS Cells; Cytoskeletal Proteins; DNA-Binding Proteins; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Lymphoid Enhancer-Binding Factor 1; Male; Mice; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Prostatic Neoplasms; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Serine; Smad7 Protein; Trans-Activators; Transcription Factors; Transforming Growth Factor beta; Tumor Cells, Cultured	2005
Kinetic characterization of novel pyrazole TGF-beta receptor I kinase inhibitors and their blockade of the epithelial-mesenchymal transition. Biochemistry, 2005, Feb-22, Volume: 44, Issue:7 Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding, Competitive; Cell Line; Chromatography, High Pressure Liquid; DNA-Binding Proteins; Epithelial Cells; Growth Inhibitors; HeLa Cells; Humans; Kinetics; MAP Kinase Kinase Kinases; Mass Spectrometry; Mesoderm; Mice; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Protein Kinase Inhibitors; Pyrazoles; Serine; Smad2 Protein; Smad3 Protein; Substrate Specificity; Trans-Activators; Transforming Growth Factor beta	2005
Palmitoylated cysteine 192 is required for RhoB tumor-suppressive and apoptotic activities. The Journal of biological chemistry, 2005, May-13, Volume: 280, Issue:19 Topics: Alanine; Amino Acid Sequence; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cysteine; DNA Primers; Genes, Tumor Suppressor; Glycine; Humans; In Situ Nick-End Labeling; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Palmitic Acid; Promoter Regions, Genetic; Protein Biosynthesis; Protein Prenylation; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; Sequence Homology, Amino Acid; Serine; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1; Transcription, Genetic; Transfection; Transforming Growth Factor beta	2005
Syndecan-1 expression in epithelial cells is induced by transforming growth factor beta through a PKA-dependent pathway. The Journal of biological chemistry, 2006, Aug-25, Volume: 281, Issue:34 Topics: Animals; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Epithelial Cells; Humans; Membrane Glycoproteins; Mice; Phosphorylation; Protein Isoforms; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteoglycans; Recombinant Proteins; Serine; Signal Transduction; Syndecan-1; Syndecans; Transforming Growth Factor beta	2006
TGF-beta modulates beta-Catenin stability and signaling in mesenchymal proliferations. Experimental cell research, 2007, Aug-01, Volume: 313, Issue:13 Topics: Animals; beta Catenin; Cell Line; Cell Proliferation; Fibroblasts; Fibromatosis, Aggressive; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Insulin-Like Growth Factor Binding Protein 6; Mesoderm; Mice; Phosphorylation; Promoter Regions, Genetic; Serine; Signal Transduction; Transcription, Genetic; Transforming Growth Factor beta; Tumor Cells, Cultured; Wnt Proteins	2007
STAT3-dependent mouse embryonic stem cell differentiation into cardiomyocytes: analysis of molecular signaling and therapeutic efficacy of cardiomyocyte precommitted mES transplantation in a mouse model of myocardial infarction. Circulation research, 2007, Oct-26, Volume: 101, Issue:9 Topics: Animals; Biomarkers; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Butadienes; Capillaries; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Drug Synergism; Embryonic Stem Cells; Enzyme Inhibitors; Leukemia Inhibitory Factor; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Myocardial Infarction; Myocytes, Cardiac; Nitriles; Phosphorylation; Serine; Signal Transduction; STAT3 Transcription Factor; Stem Cell Transplantation; Transforming Growth Factor beta; Triterpenes; Tyrosine	2007
TGFBI (BIGH3) gene mutations in Hungary--report of the novel F547S mutation associated with polymorphic corneal amyloidosis. Molecular vision, 2007, Oct-18, Volume: 13 Topics: Amino Acid Substitution; Amyloidosis; Base Sequence; Cornea; Corneal Dystrophies, Hereditary; Extracellular Matrix Proteins; Heterozygote; Humans; Hungary; Keratoplasty, Penetrating; Middle Aged; Mutation; Phenylalanine; Serine; Transforming Growth Factor beta	2007
Expression and localization of Ski determine cell type-specific TGFbeta signaling effects on the cell cycle. The Journal of cell biology, 2008, Aug-11, Volume: 182, Issue:3 Topics: Animals; Cell Cycle; Cell Differentiation; Cell Line; Cell Nucleus; Cell Proliferation; DNA-Binding Proteins; Down-Regulation; Epithelial Cells; Humans; Myelin Sheath; Organ Specificity; Phosphoproteins; Phosphorylation; Protein Binding; Protein Transport; Proto-Oncogene Proteins; Rats; Retinoblastoma Protein; Schwann Cells; Sciatic Nerve; Serine; Signal Transduction; Transforming Growth Factor beta; Up-Regulation	2008
c-Fos accelerates hepatocyte conversion to a fibroblastoid phenotype through ERK-mediated upregulation of paxillin-Serine178 phosphorylation. Molecular carcinogenesis, 2009, Volume: 48, Issue:6 Topics: Base Sequence; Cell Line, Transformed; DNA Primers; Enzyme Activation; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Hepatocytes; Humans; Microscopy, Confocal; Microscopy, Fluorescence; Paxillin; Phosphorylation; Polymerase Chain Reaction; Proto-Oncogene Proteins c-fos; Serine; Signal Transduction; Transforming Growth Factor beta; Up-Regulation	2009
Finding enzymes that are actively involved in cancer. Proceedings of the National Academy of Sciences of the United States of America, 2010, Feb-09, Volume: 107, Issue:6 Topics: Cadherins; Carcinoma, Pancreatic Ductal; Cell Cycle Proteins; Humans; Hydrolases; Intracellular Signaling Peptides and Proteins; Mutation; Neoplasm Proteins; Pancreatic Neoplasms; Phosphorylation; RNA Interference; Serine; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta	2010
Identification of a phosphorylation site in c-Ski as serine 515. Journal of biochemistry, 2010, Volume: 148, Issue:4 Topics: Amino Acid Sequence; Animals; Cell Line; DNA-Binding Proteins; Humans; Molecular Sequence Data; Phosphorylation; Proto-Oncogene Proteins; RNA, Small Interfering; Serine; Signal Transduction; Transforming Growth Factor beta	2010
Structural basis for specificity of TGFβ family receptor small molecule inhibitors. Cellular signalling, 2012, Volume: 24, Issue:2 Topics: Activin Receptors, Type I; Activins; Benzamides; Bone Morphogenetic Proteins; Crystallography, X-Ray; Dioxoles; Drug Design; HEK293 Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Mutation; Phosphorylation; Plasmids; Protein Binding; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Serine; Signal Transduction; Substrate Specificity; Transfection; Transforming Growth Factor beta	2012
p21-Activated kinase 2 (PAK2) inhibits TGF-β signaling in Madin-Darby canine kidney (MDCK) epithelial cells by interfering with the receptor-Smad interaction. The Journal of biological chemistry, 2012, Apr-20, Volume: 287, Issue:17 Topics: Animals; Dogs; Epithelial Cells; HEK293 Cells; Humans; Mice; Models, Biological; NIH 3T3 Cells; p21-Activated Kinases; Phosphorylation; Serine; Signal Transduction; Smad Proteins; Transcription Factors; Transforming Growth Factor beta	2012
N-terminal tyrosine phosphorylation of caveolin-2 negates anti-proliferative effect of transforming growth factor beta in endothelial cells. FEBS letters, 2012, Sep-21, Volume: 586, Issue:19 Topics: Amino Acid Substitution; Animals; Caveolin 2; Cell Proliferation; Cells, Cultured; Endothelial Cells; Gene Knockout Techniques; Humans; Mice; Mutagenesis, Site-Directed; Mutant Proteins; Phosphorylation; Plasminogen Activator Inhibitor 1; Protein Tyrosine Phosphatases; Recombinant Proteins; Serine; Serpin E2; Smad3 Protein; Transcriptional Activation; Transforming Growth Factor beta; Tyrosine	2012
Astrocyte-induced synaptogenesis is mediated by transforming growth factor β signaling through modulation of D-serine levels in cerebral cortex neurons. The Journal of biological chemistry, 2012, Nov-30, Volume: 287, Issue:49 Topics: Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Cognition; Culture Media, Conditioned; Electrophysiology; Humans; Mice; Models, Biological; Neurons; Patch-Clamp Techniques; Serine; Signal Transduction; Synapses; Transfection; Transforming Growth Factor beta	2012
Requirement for protein kinase A in the phosphorylation of the TGFβ receptor-interacting protein km23-1 as a component of TGFβ downstream effects. Experimental cell research, 2013, Apr-01, Volume: 319, Issue:6 Topics: Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cytoplasmic Dyneins; Fibronectins; Genes, Reporter; HEK293 Cells; Humans; Isoquinolines; Luciferases; Phosphorylation; Protein Interaction Mapping; Receptor Cross-Talk; Receptors, Transforming Growth Factor beta; Serine; Smad2 Protein; Sulfonamides; Transcriptional Activation; Transfection; Transforming Growth Factor beta	2013
Thrombin-mediated proteoglycan synthesis utilizes both protein-tyrosine kinase and serine/threonine kinase receptor transactivation in vascular smooth muscle cells. The Journal of biological chemistry, 2013, Mar-08, Volume: 288, Issue:10 Topics: Blotting, Western; Cells, Cultured; Cytoskeleton; Hemostatics; Humans; Integrins; Matrix Metalloproteinases; Microscopy, Confocal; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proteoglycans; Receptors, G-Protein-Coupled; Receptors, Transforming Growth Factor beta; rho-Associated Kinases; Serine; Smad2 Protein; Thrombin; Transcriptional Activation; Transforming Growth Factor beta	2013
TGFβ-induced PI 3 kinase-dependent Mnk-1 activation is necessary for Ser-209 phosphorylation of eIF4E and mesangial cell hypertrophy. Journal of cellular physiology, 2013, Volume: 228, Issue:7 Topics: Adaptor Proteins, Signal Transducing; Animals; Carrier Proteins; Cell Cycle Proteins; Cell Enlargement; Cells, Cultured; Eukaryotic Initiation Factor-4E; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mesangial Cells; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Serine; Signal Transduction; Transforming Growth Factor beta	2013
Serine-204 in the linker region of Smad3 mediates the collagen-I response to TGF-β in a cell phenotype-specific manner. Experimental cell research, 2013, Nov-15, Volume: 319, Issue:19 Topics: Animals; Cells, Cultured; Collagen Type I; Extracellular Signal-Regulated MAP Kinases; Mice; Mutation; Phenotype; Serine; Signal Transduction; Smad3 Protein; Trans-Activators; Transcriptional Activation; Transforming Growth Factor beta	2013
TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1. Cell cycle (Georgetown, Tex.), 2014, Volume: 13, Issue:15 Topics: Breast Neoplasms; Cell Line, Tumor; Female; Humans; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Neoplasm Invasiveness; Promoter Regions, Genetic; Prostatic Neoplasms; Serine; Snail Family Transcription Factors; TNF Receptor-Associated Factor 6; Transcription Factors; Transcriptional Activation; Transforming Growth Factor beta	2014
A crucial role for the phosphorylation of STRAP at Ser(188) by MPK38 in STRAP-dependent cell death through ASK1, TGF-β, p53, and PI3K/PDK1 signaling pathways. Cell cycle (Georgetown, Tex.), 2014, Volume: 13, Issue:21 Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Cell Line; Dinitrochlorobenzene; HEK293 Cells; Humans; Male; MAP Kinase Kinase Kinase 5; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; RNA-Binding Proteins; RNA, Small Interfering; Serine; Signal Transduction; Transforming Growth Factor beta; Tumor Suppressor Protein p53	2014
Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser16 to trigger its nuclear localization. Science signaling, 2015, Apr-14, Volume: 8, Issue:372 Topics: Active Transport, Cell Nucleus; Animals; Casein Kinase II; Cell Line, Tumor; Cell Nucleus; Cells, Cultured; Cysteine Endopeptidases; Deubiquitinating Enzymes; Embryo, Mammalian; Fibroblasts; HEK293 Cells; HeLa Cells; Humans; Immunoblotting; Lysine; Mice, Knockout; Microscopy, Fluorescence; Mutation; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; RNA Interference; Serine; Transforming Growth Factor beta; Ubiquitin-Conjugating Enzymes	2015
Identification and characterization of an hnRNP E1 translational silencing motif. Nucleic acids research, 2016, 07-08, Volume: 44, Issue:12 Topics: 3' Untranslated Regions; Base Sequence; Binding Sites; Caco-2 Cells; Cell Line, Tumor; DNA-Binding Proteins; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; HCT116 Cells; Heterogeneous-Nuclear Ribonucleoproteins; HT29 Cells; Humans; Neoplasm Metastasis; Phosphorylation; Protein Binding; Protein Domains; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Recombinant Proteins; RNA-Binding Proteins; Serine; Signal Transduction; Transforming Growth Factor beta	2016
TGF-β-induced phosphorylation of Akt and Foxo transcription factors negatively regulates induced regulatory T cell differentiation. Biochemical and biophysical research communications, 2016, Nov-04, Volume: 480, Issue:1 Topics: Animals; CD4-Positive T-Lymphocytes; Cell Differentiation; Class Ia Phosphatidylinositol 3-Kinase; Forkhead Box Protein O1; Forkhead Box Protein O3; Forkhead Transcription Factors; MAP Kinase Kinase Kinases; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Serine; T-Lymphocytes, Regulatory; Transforming Growth Factor beta	2016
Transforming Growth Factor (TGF)-β Promotes de Novo Serine Synthesis for Collagen Production. The Journal of biological chemistry, 2016, 12-30, Volume: 291, Issue:53 Topics: Cells, Cultured; Collagen; Fibroblasts; Gene Expression Regulation; Glycine Hydroxymethyltransferase; Glycolysis; Humans; Idiopathic Pulmonary Fibrosis; Lung; Phosphoglycerate Dehydrogenase; Serine; Transforming Growth Factor beta	2016
Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis. American journal of respiratory cell and molecular biology, 2018, Volume: 58, Issue:5 Topics: Airway Remodeling; Animals; Bleomycin; Collagen; Disease Models, Animal; Enzyme Inhibitors; Fibroblasts; Glycine; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Mice; Mice, Inbred C57BL; NIH 3T3 Cells; Phosphoglycerate Dehydrogenase; Serine; Signal Transduction; Transforming Growth Factor beta	2018
Peptidyl-prolyl cis-trans isomerase NIMA interacting 1 regulates skeletal muscle fusion through structural modification of Smad3 in the linker region. Journal of cellular physiology, 2018, Volume: 233, Issue:12 Topics: Animals; Cell Fusion; Cell Line; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Male; Mice, Inbred C57BL; Muscle, Skeletal; Muscular Atrophy; Myoblasts; Myostatin; NIMA-Interacting Peptidylprolyl Isomerase; Phosphorylation; Protein Binding; Serine; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta	2018
TGFBR2 mediated phosphorylation of BUB1 at Ser-318 is required for transforming growth factor-β signaling. Neoplasia (New York, N.Y.), 2020, Volume: 22, Issue:4 Topics: Amino Acid Sequence; Cell Line, Tumor; Gene Expression Regulation; Humans; Models, Biological; Phosphorylation; Protein Binding; Protein Interaction Domains and Motifs; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Serine; Signal Transduction; Transforming Growth Factor beta	2020
TGF-β Promotes Metabolic Reprogramming in Lung Fibroblasts via mTORC1-dependent ATF4 Activation. American journal of respiratory cell and molecular biology, 2020, Volume: 63, Issue:5 Topics: Activating Transcription Factor 4; Collagen; Fibroblasts; Glycine; Glycolysis; Humans; Lung; Mechanistic Target of Rapamycin Complex 1; Mitochondria; Oxygen Consumption; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Stress, Physiological; TOR Serine-Threonine Kinases; Transforming Growth Factor beta	2020
O-GlcNAc stabilizes SMAD4 by inhibiting GSK-3β-mediated proteasomal degradation. Scientific reports, 2020, 11-16, Volume: 10, Issue:1 Topics: Acetylglucosamine; Breast Neoplasms; Female; Glycogen Synthase Kinase 3 beta; Humans; Lung Neoplasms; Protein Processing, Post-Translational; Proteolysis; Serine; Signal Transduction; Smad4 Protein; Threonine; Transforming Growth Factor beta; Tumor Cells, Cultured; Ubiquitin	2020
Defective autophagy contributes to endometrial epithelial-mesenchymal transition in intrauterine adhesions. Autophagy, 2022, Volume: 18, Issue:10 Topics: Actins; Adenosine; AMP-Activated Protein Kinases; Animals; Autophagy; Cadherins; Cathepsin D; Chloroquine; Endometrium; Epithelial-Mesenchymal Transition; Female; Fibronectins; Fibrosis; Iodide Peroxidase; Lipopolysaccharides; Lysosomal-Associated Membrane Protein 1; Mice; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinases; Phosphates; Proto-Oncogene Proteins c-akt; Sequestosome-1 Protein; Serine; Sirolimus; TOR Serine-Threonine Kinases; Transforming Growth Factor beta; Triiodothyronine	2022
Casein kinase 2 promotes the TGF-β-induced activation of α-tubulin acetyltransferase 1 in fibroblasts cultured on a soft matrix. BMB reports, 2022, Volume: 55, Issue:4 Topics: Acetyltransferases; Casein Kinase II; Fibroblasts; Phosphorylation; Serine; Transforming Growth Factor beta	2022
Phosphorylation by GSK-3β increases the stability of SIRT6 to alleviate TGF-β-induced fibrotic response in renal tubular cells. Life sciences, 2022, Nov-01, Volume: 308 Topics: Animals; beta Catenin; Fibrosis; Glycogen Synthase Kinase 3 beta; Kidney; Mice; Phosphorylation; Serine; Signal Transduction; Sirtuins; Transforming Growth Factor beta	2022