Compounds > serine

serine and sulbactam

serine has been researched along with sulbactam in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Frère, JM; Ghuysen, MF; Matagne, A1
Lin, YI; Mansour, TS; Prashad, AS; Sandanayaka, VP; Williamson, RT; Yang, Y1
Bonomo, RA; Carey, MP; Carey, PR; Helfand, MS; Padayatti, PS; Totir, MA; van den Akker, F1
Bonomo, RA; Buynak, JD; Carey, MP; Carey, PR; Helfand, MS; Sheri, A; Totir, MA1
Bethel, CR; Bonomo, RA; Carey, PR; Kalp, M1
Blok, A; Pannu, NS; Tassoni, R; Ubbink, M1
Arthur, C; Bethel, CR; Bonomo, RA; Heesom, KJ; Hinchliffe, P; Papp-Wallace, KM; Schlatzer, DM; Shapiro, S; Spencer, J; Tooke, CL; Wang, B1
Balasubramanium, G; Elangovan, R; Gupta, SS; Lodha, T; Muthulakshmi, T; Perumal, V; Sivaraman, GK; Visnuvinayagam, S; Yadav, A1

Other Studies

8 other study(ies) available for serine and sulbactam

ArticleYear
Interactions between active-site-serine beta-lactamases and mechanism-based inactivators: a kinetic study and an overview.
    The Biochemical journal, 1993, Nov-01, Volume: 295 ( Pt 3)

    Topics: Actinomycetales; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Binding Sites; Clavulanic Acid; Clavulanic Acids; Hydrolysis; Kinetics; Lactams; Serine; Streptomyces; Sulbactam

1993
Spirocyclopropyl beta-lactams as mechanism-based inhibitors of serine beta-lactamases. Synthesis by rhodium-catalyzed cyclopropanation of 6-diazopenicillanate sulfone.
    Journal of medicinal chemistry, 2003, Jun-19, Volume: 46, Issue:13

    Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Catalysis; Crystallography, X-Ray; Cyclopropanes; Diazonium Compounds; Enzyme Inhibitors; Escherichia coli; Microbial Sensitivity Tests; Models, Molecular; Pseudomonas aeruginosa; Rhodium; Serine; Serratia marcescens; Spiro Compounds; Structure-Activity Relationship; Sulbactam

2003
High resolution crystal structures of the trans-enamine intermediates formed by sulbactam and clavulanic acid and E166A SHV-1 {beta}-lactamase.
    The Journal of biological chemistry, 2005, Oct-14, Volume: 280, Issue:41

    Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Binding Sites; Clavulanic Acid; Crystallography, X-Ray; Drug Resistance, Bacterial; Enzyme Inhibitors; Klebsiella pneumoniae; Models, Chemical; Models, Molecular; Mutation; Penicillanic Acid; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Serine; Spectrum Analysis, Raman; Sulbactam; Tazobactam; Time Factors; X-Rays

2005
Sulbactam forms only minimal amounts of irreversible acrylate-enzyme with SHV-1 beta-lactamase.
    Biochemistry, 2007, Aug-07, Volume: 46, Issue:31

    Topics: Acrylates; Amino Acid Substitution; beta-Lactamases; Catalytic Domain; Clavulanic Acid; Crystallization; Enzyme Inhibitors; Imines; Kinetics; Molecular Structure; Penicillanic Acid; Recombinant Proteins; Serine; Spectrum Analysis, Raman; Sulbactam; Tazobactam

2007
Why the extended-spectrum beta-lactamases SHV-2 and SHV-5 are "hypersusceptible" to mechanism-based inhibitors.
    Biochemistry, 2009, Oct-20, Volume: 48, Issue:41

    Topics: beta-Lactamase Inhibitors; beta-Lactamases; Catalytic Domain; Cephalosporins; Crystallography, X-Ray; Kinetics; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Plasmids; Serine; Spectrum Analysis, Raman; Sulbactam

2009
New Conformations of Acylation Adducts of Inhibitors of β-Lactamase from Mycobacterium tuberculosis.
    Biochemistry, 2019, 02-19, Volume: 58, Issue:7

    Topics: Acylation; Aldehydes; Amino Acid Substitution; Azabicyclo Compounds; beta-Lactamase Inhibitors; beta-Lactamases; Catalytic Domain; Clavulanic Acid; Crystallography, X-Ray; Mycobacterium tuberculosis; Protein Conformation; Serine; Sulbactam; Tazobactam

2019
Penicillanic Acid Sulfones Inactivate the Extended-Spectrum β-Lactamase CTX-M-15 through Formation of a Serine-Lysine Cross-Link: an Alternative Mechanism of β-Lactamase Inhibition.
    mBio, 2022, 06-28, Volume: 13, Issue:3

    Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Lysine; Microbial Sensitivity Tests; Serine; Sulbactam; Tazobactam

2022
Prevalence of S. aureus and/or MRSA from seafood products from Indian seafood products.
    BMC microbiology, 2022, 10-01, Volume: 22, Issue:1

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cefoxitin; Gentamicins; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Multilocus Sequence Typing; Ofloxacin; Piperacillin; Prevalence; Rifampin; Seafood; Serine; Staphylococcal Infections; Staphylococcus aureus; Sulbactam; Tazobactam; Trimethoprim, Sulfamethoxazole Drug Combination; Virulence Factors

2022