serine has been researched along with organophosphonates in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (37.84) | 18.7374 |
| 1990's | 2 (5.41) | 18.2507 |
| 2000's | 9 (24.32) | 29.6817 |
| 2010's | 12 (32.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berman, HA; Epstein, DJ; Taylor, P | 1 |
| Lewis, WS; Schuster, SM | 1 |
| Kuyl-Yeheskiely, E; Schaeffer, AH; Tromp, CM; van Boom, JH; van der Marel, GA | 1 |
| Becker, EL | 3 |
| Hill, JH; Ward, PA | 1 |
| Broomfield, CA; Hackley, BE; Morrisett, JD | 1 |
| Hsia, JC; Kosman, DJ; Piette, LH | 1 |
| Kosman, DJ; Piette, LH | 1 |
| Baer, E; Eber, JT | 1 |
| Dana, R; Douste-Blazy, L | 1 |
| Bonsen, PP; Burbach-Westerhuis, GJ; De Haas, GH; Van Deenen, LL | 1 |
| Becker, EL; Pearlman, DS; Ward, PA | 1 |
| Diller, A; Schirch, LV | 1 |
| Barford, D; Burke, TR; Chen, L; Jia, Z; Wang, S; Yan, X; Ye, B; Zhang, ZY | 1 |
| Enyedy, EJ; Kovach, IM | 1 |
| Kele, Z; Kupihár, Z; Tóth, GK | 1 |
| Hermetter, A; Oskolkova, OV | 1 |
| Chen, JM; Margot, NA; Miller, MD; Naeger, LK; Petropoulos, CJ; Swaminathan, S; White, KL; Wrin, T | 1 |
| Cole, PA; Klein, DC; Lebeau, A; Schwarzer, D; Weller, JL; Zheng, W | 1 |
| Davies, C; Gutheil, WG; Nicholas, RA; Nicola, G; Peddi, S; Stefanova, M | 1 |
| Aerts, BN; Dijkstra, HP; Egmond, MR; Klein Gebbink, RJ; Kruithof, CA; Sprong, H | 1 |
| Bauer, I; Freynhagen, R; Hermanns, H; Kollosche, K; Lipfert, P; Muth-Selbach, U; Stegmann, JU | 1 |
| Motomizu, S; Oshima, M; Oshita, K; Sabarudin, A; Takayanagi, T | 1 |
| De-Paula, VJ; Forlenza, OV; Gattaz, WF; Schaeffer, EL; Talib, LL | 1 |
| Cravatt, BF; Simon, GM | 1 |
| Hernández-Núñez, E; Labastida-Galván, V; Lagunas-Rivera, S; Ordóñez, M | 1 |
| Kashemirov, BA; Krylov, IS; McKenna, CE; Peterson, LW; Sala-Rabanal, M; Serpi, M | 1 |
| Borysko, K; Breitenbach, J; Drach, JC; Hilfinger, J; Kashemirov, BA; Kijek, P; Kim, JS; McKenna, CE; Mitchell, S; Peterson, LW | 1 |
| Sirin, GS; Zhang, Y | 1 |
| Álvarez, E; Fernández, R; Lassaletta, JM; Monge, D; Serrano, I | 1 |
| Kimura, H; Nakao, K; Sakimura, K; Suzuki, M; Yoshikawa, M | 1 |
| Boto, A; Hernández, D; Saavedra, CJ | 1 |
| Amieva, MR; Bogyo, M; Cooper, R; Crawford, LA; Garland, M; Lentz, CS; Sheldon, JR; Skaar, EP; Weerapana, E | 1 |
| Abegg, D; Adibekian, A; Dwyer, BG; Wang, C | 1 |
| d'Andrea, FB; Townsend, CA | 1 |
2 review(s) available for serine and organophosphonates
| Article | Year |
|---|---|
Enzyme activation and the mechanism of neutrophil chemotaxis.
Topics: Actomyosin; Amino Acids; Animals; Bacteria; Binding Sites; Biochemical Phenomena; Biochemistry; Calcium; Chemotaxis; Complement System Proteins; Cyclic AMP; Enzyme Activation; Enzyme Precursors; Esterases; Histamine Release; Horses; In Vitro Techniques; Leukocytes; Magnesium; Neutrophils; Organophosphonates; Oxygen Consumption; Rabbits; Serine | 1974 |
Activity-based proteomics of enzyme superfamilies: serine hydrolases as a case study.
Topics: Animals; Biochemistry; Catalysis; Catalytic Domain; Enzymes; Genome; Humans; Hydrolases; Organophosphonates; Peptide Hydrolases; Proteome; Proteomics; Serine | 2010 |
35 other study(ies) available for serine and organophosphonates
| Article | Year |
|---|---|
Ligand-induced conformational changes in acetylcholinesterase investigated with fluorescent phosphonates.
Topics: Acetylcholinesterase; Animals; Binding Sites; Dansyl Compounds; Electric Organ; Fishes; Fluorescent Dyes; Kinetics; Ligands; Organophosphonates; Protein Conformation; Serine; Spectrophotometry; Zinc | 1979 |
Structural requirements for nucleophilic substrates of carboxypeptidase Y.
Topics: beta-Alanine; Carboxypeptidases; Hydrolysis; In Vitro Techniques; Oligopeptides; Organophosphonates; Peptidyl Transferases; Serine; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity; Sulfonic Acids | 1991 |
A model study directed towards the preparation of nucleopeptides via H-phosphonate intermediates.
Topics: Indicators and Reagents; Magnetic Resonance Spectroscopy; Nucleoproteins; Organophosphonates; Peptide Fragments; Serine; Structure-Activity Relationship; Threonine; Tyrosine | 1987 |
C3 leukotactic factors produced by a tissue protease.
Topics: Amino Acids; Animals; Antibodies; Beta-Globulins; Blood; Blood Chemical Analysis; Centrifugation, Density Gradient; Chemotaxis; Chromatography, Gel; Complement System Proteins; Culture Techniques; Esterases; Esters; Immunodiffusion; Male; Molecular Weight; Myocardium; Neutrophils; Organophosphonates; Peptide Hydrolases; Rabbits; Rats; Serine; Trypsin Inhibitors | 1969 |
A new spin label specific for the active site of serine enzymes.
Topics: Acetylcholinesterase; Animals; Binding Sites; Brain Chemistry; Cattle; Cell Membrane; Chemical Phenomena; Chemistry; Chymotrypsin; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Erythrocytes; Fluorine; Free Radicals; Humans; Nerve Endings; Organophosphonates; Piperidines; Rats; Serine | 1969 |
ESR probing of macromolecules: spin-labeling of the active sites of the proteolytic serine enzymes.
Topics: Animals; Binding Sites; Blood; Cattle; Cholinesterases; Chymotrypsin; Electron Spin Resonance Spectroscopy; Erythrocytes; Esterases; Fluorides; Horses; Hydrogen-Ion Concentration; Kinetics; Organophosphonates; Pancreatic Elastase; Peptide Hydrolases; Protein Binding; Protein Conformation; Serine; Subtilisins; Thrombin; Trypsin Inhibitors | 1972 |
ESR probing of macromolecules: spin label study of the conformational integrity and transitions in modified alpha-chymotrypsin.
Topics: Alkylation; Binding Sites; Chymotrypsin; Electron Spin Resonance Spectroscopy; Fluorides; Hydrogen-Ion Concentration; Kinetics; Methionine; Organophosphonates; Oxidation-Reduction; Protein Conformation; Serine; Spectrophotometry, Ultraviolet | 1972 |
Phosphonolipids. XXVII. Synthesis of O-(2-aminoethyl)phosphono-L-serine and its stereoisomer.
Topics: Chromatography, Thin Layer; Ethylamines; Organophosphonates; Phospholipids; Phosphoserine; Serine; Spectrophotometry, Infrared; Stereoisomerism | 1974 |
The relationship of the chemotactic behavior of the complement-derived factors, C3a, C5a, and C567, and a bacterial chemotactic factor to their ability to activate the proesterase 1 of rabbit polymorphonuclear leukocytes.
Topics: Animals; Bacteria; Chemotaxis; Complement System Proteins; Enzyme Precursors; Escherichia coli; Esterases; In Vitro Techniques; Leukocytes; Molecular Weight; Neutrophils; Organophosphonates; Rabbits; Serine | 1972 |
[Influence of 2 amino ethylphosphonic acid on the incorporation in vitro of 32P in cerebral phospholipids].
Topics: Amines; Animals; Autoradiography; Brain; Chromatography, Thin Layer; Mice; Organophosphonates; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Phosphorus Isotopes; Serine | 1969 |
Chemical synthesis of some lecithin analogues potential inhibitors of phospholipase A.
Topics: Acetone; Acylation; Alcohols; Animals; Chlorine; Chromatography; Chromatography, Thin Layer; Fatty Acids; Glycerol; Glycerophosphates; Lysophosphatidylcholines; Organophosphonates; Phosphatidylcholines; Phospholipases; Phospholipids; Serine; Snakes; Stereoisomerism; Sulfonic Acids; Tosyl Compounds; Venoms | 1972 |
The requirement of serine esterase function in complement-dependent erythrophagocytosis.
Topics: Animals; Chemotaxis; Complement System Proteins; Enzyme Activation; Esterases; Esters; Guinea Pigs; Hydrogen-Ion Concentration; Leukocytes; Organophosphonates; Phagocytosis; Serine; Temperature | 1969 |
Phosphonate inhibition of theaccumulation and retention of K+ by rabbit neutrophils in relation to chemotaxis.
Topics: Animals; Chemotaxis; Cholinesterase Inhibitors; Chymotrypsin; Enzyme Activation; Esterases; Filtration; Neutrophils; Organophosphonates; Potassium; Rabbits; Serine | 1971 |
Serine transhydroxymethylase. Affinity of the active site for substrates, substrate analogues, and anions.
Topics: Alanine; Aldehydes; Aminoisobutyric Acids; Animals; Benzoates; Binding Sites; Chlorides; Cysteamine; Cysteine; Electrophoresis; Folic Acid; Glycine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Models, Biological; Organophosphonates; Phosphates; Potassium; Propionates; Pyridoxal Phosphate; Rabbits; Serine; Spectrophotometry; Stereoisomerism; Sulfates; Sulfhydryl Compounds; Sulfonic Acids; Thermodynamics; Threonine; Transferases; Ultracentrifugation | 1971 |
Small molecule interactions with protein-tyrosine phosphatase PTP1B and their use in inhibitor design.
Topics: Binding Sites; Calorimetry; Computer Simulation; Crystallography, X-Ray; Cysteine; Drug Design; Enzyme Inhibitors; Kinetics; Models, Molecular; Naphthalenes; Organophosphonates; Phosphotyrosine; Point Mutation; Protein Conformation; Protein Structure, Secondary; Protein Tyrosine Phosphatases; Recombinant Proteins; Serine | 1996 |
Reversible modulation of human factor Xa activity with phosphonate esters: media effects.
Topics: Binding Sites; Enzyme Activation; Enzyme Inhibitors; Esterification; Factor Va; Factor Xa; Factor Xa Inhibitors; Humans; Hydrogen-Ion Concentration; Kinetics; Ligands; Lipid Bilayers; Models, Chemical; Organophosphonates; Phosphatidylserines; Phospholipids; Serine; Stereoisomerism | 2000 |
The H-phosphonate approach to the synthesis of phosphopeptides on solid phase.
Topics: Chromatography, High Pressure Liquid; Organophosphonates; Phosphopeptides; Phosphorylation; Serine; Tyrosine | 2001 |
Fluorescent inhibitors reveal solvent-dependent micropolarity in the lipid binding sites of lipases.
Topics: 2-Naphthylamine; Binding Sites; Burkholderia cepacia; Enzyme Inhibitors; Fluorescent Dyes; Lipase; Lipids; Molecular Structure; Naphthalenes; Nitrophenols; Organophosphonates; Protein Conformation; Rhizopus; Serine; Solvents; Spectrometry, Fluorescence | 2002 |
Molecular mechanisms of tenofovir resistance conferred by human immunodeficiency virus type 1 reverse transcriptase containing a diserine insertion after residue 69 and multiple thymidine analog-associated mutations.
Topics: Adenine; Adenosine Triphosphate; Cells, Cultured; DNA Primers; DNA Transposable Elements; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Models, Molecular; Mutation; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Serine; Tenofovir; Thymidine | 2004 |
Cellular stability of serotonin N-acetyltransferase conferred by phosphonodifluoromethylene alanine (Pfa) substitution for Ser-205.
Topics: 14-3-3 Proteins; Alanine; Amino Acids; Animals; Arylalkylamine N-Acetyltransferase; CHO Cells; Cloning, Molecular; Cricetinae; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Hydrocarbons; Immunohistochemistry; Kinetics; Mass Spectrometry; Melatonin; Methane; Models, Biological; Models, Chemical; Organophosphonates; Peptides; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteins; Serine; Sheep | 2005 |
Crystal structure of Escherichia coli penicillin-binding protein 5 bound to a tripeptide boronic acid inhibitor: a role for Ser-110 in deacylation.
Topics: Acylation; Amino Acid Chloromethyl Ketones; Binding Sites; Boronic Acids; Catalysis; Crystallography, X-Ray; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Enzyme Inhibitors; Escherichia coli Proteins; Hydrolysis; Oligopeptides; Organophosphonates; Penicillin-Binding Proteins; Serine; Streptococcus pneumoniae; Streptomyces; Substrate Specificity | 2005 |
Selective and diagnostic labelling of serine hydrolases with reactive phosphonate inhibitors.
Topics: Affinity Labels; Binding Sites; Dansyl Compounds; Hydrolases; Kinetics; Nitrophenols; Organophosphonates; Proteome; Serine; Spectrometry, Fluorescence; Substrate Specificity | 2008 |
Antinociceptive effects of systemic lidocaine: involvement of the spinal glycinergic system.
Topics: Analgesics; Animals; Binding Sites; Glycine; Glycine Agents; Lidocaine; Organophosphonates; Pain; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Spinal Cord; Substrate Specificity; Synaptic Transmission | 2009 |
Adsorption behavior of uranium(VI) and other ionic species on cross-linked chitosan resins modified with chelating moieties.
Topics: Adsorption; Arsenicals; Catechols; Chelating Agents; Chitosan; Cross-Linking Reagents; Imino Acids; Lanthanoid Series Elements; Organophosphonates; Serine; Uranium | 2009 |
Inhibition of phospholipase A2 increases tau phosphorylation at Ser214 in embryonic rat hippocampal neurons.
Topics: Animals; Antibodies, Phospho-Specific; Arachidonic Acids; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hippocampus; Neurons; Organophosphonates; Phospholipase A2 Inhibitors; Phospholipases A2, Calcium-Independent; Phosphorylation; Protein Processing, Post-Translational; Rats; Rats, Wistar; Serine; tau Proteins | 2010 |
Synthesis of syn-gamma-amino-beta-hydroxyphosphonates by reduction of beta-ketophosphonates derived from L-proline and L-serine.
Topics: Magnetic Resonance Spectroscopy; Mass Spectrometry; Organophosphonates; Oxidation-Reduction; Proline; Serine; Stereoisomerism | 2010 |
Serine side chain-linked peptidomimetic conjugates of cyclic HPMPC and HPMPA: synthesis and interaction with hPEPT1.
Topics: Adenine; Cytosine; Dipeptides; Humans; Molecular Structure; Organophosphonates; Organophosphorus Compounds; Peptide Transporter 1; Prodrugs; Serine; Stereoisomerism; Symporters | 2010 |
Synthesis, transport and antiviral activity of Ala-Ser and Val-Ser prodrugs of cidofovir.
Topics: Administration, Oral; Alanine; Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Molecular Structure; Organophosphonates; Peptides; Prodrugs; Rats; Serine; Valine | 2011 |
How is acetylcholinesterase phosphonylated by soman? An ab initio QM/MM molecular dynamics study.
Topics: Acetylcholinesterase; Fluorine; Molecular Dynamics Simulation; Molecular Structure; Organophosphonates; Quantum Theory; Serine; Soman | 2014 |
Asymmetric organocatalytic synthesis of quaternary α-hydroxy phosphonates: en route to α-aryl phosphaisoserines.
Topics: Catalysis; Chemistry Techniques, Synthetic; Formaldehyde; Models, Molecular; Molecular Conformation; Organophosphonates; Serine; Stereoisomerism; Urea | 2015 |
A novel Na(+) -Independent alanine-serine-cysteine transporter 1 inhibitor inhibits both influx and efflux of D-Serine.
Topics: Amino Acid Transport System ASC; Animals; Cells, Cultured; CHO Cells; Cobamides; Cricetulus; Cyclohexanes; Cysteine; Dose-Response Relationship, Drug; Embryo, Mammalian; Hippocampus; Male; Microdialysis; Minor Histocompatibility Antigens; Neurons; Organophosphonates; Rats; Rats, Sprague-Dawley; Rats, Wistar; Serine; Sodium | 2016 |
Metal-Free, Site-Selective Peptide Modification by Conversion of "Customizable" Units into β-Substituted Dehydroamino Acids.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Biochemical Phenomena; Organophosphonates; Peptides; Protein Binding; Protein Conformation; Serine; Threonine | 2018 |
Identification of a S. aureus virulence factor by activity-based protein profiling (ABPP).
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Cloning, Molecular; Fatty Acids; Genetic Techniques; HEK293 Cells; Host-Pathogen Interactions; Humans; Hydrolases; Hydrolysis; Kinetics; Mice; Microbial Sensitivity Tests; Organophosphonates; Phylogeny; Proteomics; Serine; Staphylococcal Infections; Staphylococcus aureus; Virulence; Virulence Factors | 2018 |
Discovery and Evaluation of New Activity-Based Probes for Serine Hydrolases.
Topics: Azides; Click Chemistry; Humans; Hydrolases; Molecular Probes; Organophosphonates; Serine | 2019 |
Late-Stage Conversion of Diphenylphosphonate to Fluorophosphonate Probes for the Investigation of Serine Hydrolases.
Topics: Fluorescent Dyes; Humans; Hydrolases; Hydrolysis; Molecular Structure; Organophosphonates; Serine | 2019 |