serine has been researched along with nadp in 104 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (35.58) | 18.7374 |
| 1990's | 18 (17.31) | 18.2507 |
| 2000's | 23 (22.12) | 29.6817 |
| 2010's | 22 (21.15) | 24.3611 |
| 2020's | 4 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Beck, SD; Griffiths, GW; Houk, EJ | 1 |
| Garnak, M; Reeves, HC | 1 |
| Goldberg, I; Mateles, RI | 1 |
| Borhani, DW; Harter, TM; Petrash, JM | 1 |
| Dean, AM; Koshland, DE; Lee, MH | 1 |
| Schirch, V; Strong, WB | 1 |
| Kikuchi, G; Yoshida, T | 2 |
| Frisell, WR; Randolph, VM | 1 |
| Chiba, H; Kitagawa, Y; Nakanishi, K; Sugimoto, E | 1 |
| Diamond, LS; Weinbach, EC | 1 |
| Kobayashi, K; Lindros, KO; Okawa, K; Parrilla, R; Williamson, JR; Zimmerman, UJ | 1 |
| Cohen, GN; Truffa-Bachi, P; Veron, M | 1 |
| Knöfel, R; Müller, M; Rapoport, S | 1 |
| Braun, PE; Snell, EE | 2 |
| Pristoupilová, K | 1 |
| Gräser, H | 1 |
| Pizer, LI; Sugimoto, E | 1 |
| Albrecht, AM; Hutchison, DJ; Pearce, FK | 1 |
| Davies, DD; Slaughter, JC | 1 |
| LeKim, D; Sticht, G; Stoffel, W | 1 |
| Brady, RN; Di Mari, SJ; Snell, EE | 2 |
| Bryan, JK | 1 |
| Kikuchi, G; Kochi, H | 1 |
| Santarius, KA; Stocking, CR | 1 |
| Braun, PE; Morell, P; Radin, NS | 1 |
| Heinemann, M; Sloane, NH | 1 |
| Rosenblum, IY; Sallach, HJ | 1 |
| Black, CC; Lee, SS; Travis, J | 1 |
| Johnstone, RM; Trachewsky, D | 1 |
| Turner, JM; Willetts, AJ | 1 |
| Hammond, RK; Sweeley, CC | 1 |
| Booth, IR; Findlay, MJ; Kroll, RG; Rowland, GC; Stewart, LM | 1 |
| Arceneaux, JE; Byers, BR; Gaines, CG; Lodge, JS | 1 |
| Hopkins, N; Williams, CH | 1 |
| Baltas, M; Boudet, AM; Douglas, KT; Feuillet, C; Gorrichon, L; Grima-Pettenati, J; Kennedy, K; Lauvergeat, V; McKie, JH | 1 |
| Aliverti, A; Bruns, CM; Curti, B; Karplus, PA; Pandini, VE; Vanoni, MA; Zanetti, G | 1 |
| Drijfhout, MC; Eppink, MH; Hagen, WR; van Berkel, WJ; van der Bolt, FJ | 1 |
| Appling, DR; García-Martínez, LF | 1 |
| Décout, JL; Fieschi, F; Fontecave, M; Nivière, V | 1 |
| Kasper, CB; Shen, AL | 1 |
| Breton, R; Fontecilla-Camps, JC; Housset, D; Mazza, C | 1 |
| Bryant, DA; Golbeck, JH; Jung, YS; Qiao, F; Vassiliev, IR; Yang, F | 1 |
| Benson, TE; Massey, V; Walsh, CT | 1 |
| Lee, H; Zhang, Y | 1 |
| Sahm, H; Sprenger, GA; Wiegert, T | 1 |
| Eppink, MH; Schreuder, HA; van Berkel, WJ | 1 |
| Arscott, LD; Krauth-Siegel, RL; Schirmer, RH; Schönleben-Janas, A; Williams, CH | 1 |
| Charrier, V; Claiborne, A; Luba, J | 1 |
| Claiborne, A; Mallett, TC; Parsonage, D | 1 |
| Barber, MJ; Pollock, VV | 1 |
| Beernink, PT; Doyle, SA; Koshland, DE | 1 |
| Hubbard, PA; Kasper, CB; Kim, JJ; Paschke, R; Shen, AL | 1 |
| Han, O; Kim, C; Kim, H | 1 |
| Azzi, A; Bellemare, V; Chang, HJ; Huang, YW; Laberge, S; Lin, SX; Pineau, I | 1 |
| Aung-Hilbrich, LM; Hillen, W; Seidel, G; Wagner, A | 1 |
| Berndt, KD; Chiaraluce, R; Consalvi, V; Ladenstein, R; Lebbink, JH | 1 |
| Mendelsohn, ME; Takahashi, S | 1 |
| Guo, X; Jin, X; Qi, Y; Wang, M | 1 |
| Althage, M; Karlsson, J; Rydström, J | 1 |
| Stout, CD; Yamaguchi, M | 1 |
| BARRATT, RW | 1 |
| POMEROY, LR; ROACH, MK; SIEGEL, FL | 1 |
| Igarashi, Y; Kihara, A | 1 |
| Bohren, KM; Brownlee, JM; Gabbay, KH; Harrison, DH; Milne, AC | 1 |
| Abali, EE; Banerjee, D; Bertino, JR; Menon, LG; Mishra, PJ; Peters, R; Skacel, N | 1 |
| Finazzi, G; Hippler, M; Sommer, F | 1 |
| Goda, S; Kawakami, R; Kawarabayasi, Y; Ohshima, T; Sakuraba, H; Shimizu, Y | 1 |
| Hatakeyama, K; Kalyanaraman, B; Martásek, P; Schauer, DW; Vásquez-Vivar, J; Whitsett, J; Zhao, H | 1 |
| Fushinobu, S; Kuzuyama, T; Nishiyama, M; Tomita, T | 1 |
| Holton, JM; Hung, LW; Kim, SI; Park, MS; Pédelacq, JD; Rho, BS; Terwilliger, TC; Vigil, D | 1 |
| Gao, YT; Martásek, P; Masters, BS; Panda, SP; Roman, LJ; Salerno, JC | 1 |
| Cheng, H; Gao, F; Gao, GF; Liu, Y; Peng, H; Thompson, J; Zhang, Q | 1 |
| Dunford, AJ; Girvan, HM; Munro, AW; Scrutton, NS | 1 |
| Ghosh, I; Vinekar, R | 1 |
| Anderson, DD; Stover, PJ | 1 |
| Dickert, F; Dobbek, H; Knauer, SH; Mende, S; Spiegelhauer, O; Ullmann, GM | 1 |
| Erales, J; Gontero, B; Mekhalfi, M; Woudstra, M | 1 |
| Battistuzzi, G; Bellei, M; Cowan, JA; Mansy, SS; Sola, M; Wu, SP | 1 |
| Brychkova, G; Sagi, M; Ventura, Y; Yarmolinsky, D | 1 |
| Basso, LA; Caceres, RA; de Azevedo, WF; Rosado, LA; Santos, DS | 1 |
| Araki, T; Nikki, T; Ohshima, T; Sakuraba, H; Shibata, T; Yoneda, K | 1 |
| Engel, PC; Khan, AR; Oliveira, TF; Sharkey, MA | 1 |
| Badieyan, S; Shirey, C; Sobrado, P | 1 |
| Bertino, JR; Boros, LG; Chan, LL; DiPaola, RS; Dolfi, SC; Dvorzhinski, D; Gounder, M; Hirshfield, KM; Lin, H; Markert, EK; Oltvai, ZN; Qiu, J; Tedeschi, PM; Vazquez, A | 1 |
| Fan, J; Kamphorst, JJ; Rabinowitz, JD; Shlomi, T; Thompson, CB; Ye, J | 1 |
| Feist, AM; Fiske, BP; Green, CR; Gui, DY; Lewis, CA; McCloskey, D; Metallo, CM; Parker, SJ; Vander Heiden, MG; Vokes, NI | 1 |
| Aiso, S; Hamase, K; Imanishi, N; Kuwasako, K; Matsuoka, M; Miyoshi, Y; Muto, Y; Sasabe, J; Suzuki, M | 1 |
| Koduru, L; Lakshmanan, M; Lee, DY; Yu, K | 1 |
| Chen, W; Harbeck, MC; He, D; Peng, H; Xie, L; Zhuang, Y | 1 |
| Kawabata, Y; Kawai, S; Murata, K | 1 |
| Chen, L; Ducker, GS; Esposito, M; Ghergurovich, JM; Kang, Y; Morscher, RJ; Rabinowitz, JD; Teng, X | 1 |
| Bruno, S; Campanini, B; Dellafiora, L; Faggiano, S; Marchesani, F; Margiotta, M; Mozzarelli, A | 1 |
| Crespo, JL; Lemaire, SD; Pérez-Pérez, ME | 1 |
| Du, J; Gillies, MC; Grünert, U; Madigan, MC; Shen, W; Yam, M; Zhang, T; Zhou, F; Zhu, L | 1 |
| Becker-Kettern, J; Conrotte, JF; Fiehn, O; Jung, PP; Linster, CL; Paczia, N; Steinmetz, LM; Zhu, C | 1 |
| Asara, JM; Ben-Sahra, I; Byles, V; Gao, P; Henning, GT; Hoxhaj, G; Lockwood, SE; Manning, BD; Selfors, LM; Timson, RC | 1 |
| Cahir-McFarland, E; Ersing, I; Gewurz, BE; Gygi, SP; Ma, Y; Mootha, VK; Nobre, L; Nomburg, J; Paulo, JA; Reinstadler, B; Shen, H; Smith, NA; Sommermann, T; Trudeau, S; Wang, LW; Wang, Z; Weekes, MP | 1 |
| Gao, HY; Li, Y; Li, YT; Liu, MJ; Liu, P; Zhang, ZS; Zhao, SJ | 1 |
| But, SY; Khmelenina, VN; Mustakhimov, II; Reshetnikov, AS; Rozova, ON | 1 |
| Clasquin, MF; Rabinowitz, JD; TeSlaa, T; Tesz, GJ; Xing, G; Xu, X; Yang, L; Zeng, X; Zhang, Z | 1 |
| Ishikawa, T; Kawai-Yamada, M; Kono, M; Miyagi, A; Nagano, M; Noguchi, K; Suzuki, S; Takahara, K; Tanaka, D; Yamaguchi, M | 1 |
1 review(s) available for serine and nadp
| Article | Year |
|---|---|
Structure, function, and possible origin of a bifunctional allosteric enzyme, Escherichia coli aspartokinase I-homoserine dehydrogenase I.
Topics: Adenosine Triphosphate; Alcohol Oxidoreductases; Allosteric Regulation; Amino Acids; Antigen-Antibody Reactions; Aspartic Acid; Binding Sites; Electrophoresis, Disc; Escherichia coli; Homoserine; Kinetics; Mercaptopurine; Molecular Weight; Multienzyme Complexes; NAD; NADP; Peptide Fragments; Phosphotransferases; Protein Binding; Protein Conformation; Ribonucleotides; Serine; Spectrophotometry; Sulfhydryl Compounds; Threonine | 1974 |
103 other study(ies) available for serine and nadp
| Article | Year |
|---|---|
Lipid metabolism in the symbiotes of the pea aphid, Acyrthosiphon pisum.
Topics: Acetates; Adenosine Triphosphate; Animals; Aphids; Choline; Lipid Metabolism; Methionine; Mevalonic Acid; NADP; Phospholipids; Plants; Rickettsiaceae; Serine; Sterols | 1976 |
Phosphorylation of Isocitrate dehydrogenase of Escherichia coli.
Topics: Acetates; Escherichia coli; Isocitrate Dehydrogenase; NADP; Phosphorylation; Protein Kinases; Serine; Threonine | 1979 |
Growth of Pseudomonas C on C1 compounds: enzyme activites in extracts of Pseudomonas C cells grown on methanol, formaldehyde, and formate as sole carbon sources.
Topics: Alcohol Oxidoreductases; Cell Fractionation; Cell-Free System; Chromatography, Gas; Formaldehyde; Formates; Glucose; Glyceric Acids; Hexosephosphates; Hexoses; Ligases; Methanol; NAD; NADP; Oxidation-Reduction; Pseudomonas; Serine; Spectrophotometry | 1975 |
The crystal structure of the aldose reductase.NADPH binary complex.
Topics: Aldehyde Reductase; Amino Acid Sequence; Binding Sites; Cloning, Molecular; Cysteine; Escherichia coli; Humans; Models, Molecular; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Protein Conformation; Recombinant Proteins; Serine | 1992 |
Phosphorylation inactivates Escherichia coli isocitrate dehydrogenase by preventing isocitrate binding.
Topics: Binding Sites; Escherichia coli; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Lysine; Mutation; NADP; Phosphorylation; Protein Binding; Serine; Templates, Genetic | 1989 |
In vitro conversion of formate to serine: effect of tetrahydropteroylpolyglutamates and serine hydroxymethyltransferase on the rate of 10-formyltetrahydrofolate synthetase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Formate-Tetrahydrofolate Ligase; Formates; Glutamates; Glycine Hydroxymethyltransferase; Kinetics; Ligases; Liver; Methyltransferases; NADP; Oxidation-Reduction; Rabbits; Serine; Tetrahydrofolates; Transferases | 1989 |
Significance of the glycine cleavage system in glycine and serine catabolism in avian liver.
Topics: Ammonium Chloride; Animals; Arylformamidase; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Chickens; Columbidae; Cycloserine; Cysteine; Enzyme Activation; Folic Acid; Glycine; Hydroxylamines; Hypoxanthines; L-Serine Dehydratase; Liver; Male; Mitochondria, Liver; NAD; NADP; Oxidoreductases; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Semicarbazides; Serine; Species Specificity; Subcellular Fractions; Transferases; Uric Acid | 1971 |
Effect of adenine nucleotides on the oxidation of methyl groups in liver mitochondria.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Carbon Dioxide; Dinitrophenols; Folic Acid; Formaldehyde; Formates; Glycine; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methylation; Mitochondria, Liver; Mitochondrial Swelling; NAD; NADP; Oxygen Consumption; Rats; Rotenone; Sarcosine; Semicarbazides; Serine | 1973 |
Purification and properties of beef liver D-glycerate dehydrogenase.
Topics: Alcohol Oxidoreductases; Animals; Cattle; Electrophoresis; Enzyme Activation; Fructosephosphates; Glyceric Acids; Liver; Molecular Weight; NAD; NADP; Pyruvates; Serine; Spectrophotometry; Ultracentrifugation | 1972 |
Entamoeba histolytica. I. Aerobic metabolism.
Topics: Aerobiosis; Catalase; Chloromercuribenzoates; Cinnamates; Citric Acid Cycle; Culture Media; Cyanides; Entamoeba histolytica; Ethanol; Fructose; Galactose; Glucose; Hydrogen-Ion Concentration; Iodoacetates; Metronidazole; NAD; NADP; Oxygen Consumption; Preservation, Biological; Serine; Sulfhydryl Compounds; Vitamin K | 1974 |
Functional compartmentation of acetaldehyde oxidation in rat liver.
Topics: Acetaldehyde; Acetates; Aldehyde Oxidoreductases; Animals; Biological Transport; Carbon Radioisotopes; Ethanol; Flavins; Glucose; Lactates; Liver; Male; NAD; NADP; Oleic Acids; Oxygen Consumption; Perfusion; Pyrazoles; Pyruvates; Rats; Serine; Spectrometry, Fluorescence; Time Factors | 1974 |
[Formiate metabolism in the red blood cell].
Topics: Carbon Dioxide; Carbon Isotopes; Erythrocytes; Formates; Glutathione; Glycine; Histidine; Humans; Methylene Blue; NADP; Peroxidases; Peroxides; Reticulocytes; Serine | 1968 |
The biosynthesis of dihydrosphingosine in cell-free preparations of Hansenula ciferri.
Topics: Aldehydes; Amino Alcohols; Ascomycota; Carbon Isotopes; Chromatography, Thin Layer; Coenzyme A; Lipids; NADP; Palmitic Acids; Pyridoxal Phosphate; Serine | 1967 |
Biosynthesis of methionine in the liver of leukaemic mice.
Topics: Animals; Carbon Isotopes; Female; Leukemia, Experimental; Liver; Lymph Nodes; Male; Methionine; Mice; NADP; Organ Size; Serine; Spleen; Thymus Gland | 1967 |
[The cofactors of serine synthesis in primary root homogenates of Zea mays].
Topics: Adenosine Triphosphate; Biotin; Buffers; Chromatography; Electrophoresis; Folic Acid; NADP; Poaceae; Pyridoxal Phosphate; Serine; Vitamin B 12 | 1966 |
The mechanism of end product inhibition of serine biosynthesis. I. Purification and kinetics of phosphoglycerate dehydrogenase.
Topics: Alcohol Oxidoreductases; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Electrophoresis; Escherichia coli; Glyceric Acids; Hydrogen-Ion Concentration; Kinetics; NAD; NADP; Phosphates; Pyruvates; Serine; Streptomycin; Ultracentrifugation | 1968 |
Methylenetetrahydrofolate dehydrogenase of the amethopterin-resistant strain Streptococcus faecium var. durans A and its repressibility by serine.
Topics: Aminohydrolases; Culture Media; Enzyme Repression; Kinetics; Ligases; Methotrexate; NADP; Protein Hydrolysates; Serine; Spectrophotometry; Streptococcus; Tetrahydrofolate Dehydrogenase; Transferases | 1968 |
Biosynthesis of sphingolipid bases. II. Keto intermediates in synthesis of sphingosine and dihydrosphingosine by cell-free extracts of Hansenula ciferri.
Topics: Amino Alcohols; Ascomycota; Autoradiography; Carbon Isotopes; Cell-Free System; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Coenzyme A; Crystallization; Cysteine; Ketones; Models, Biological; NADP; Palmitic Acids; Serine; Stimulation, Chemical | 1968 |
The isolation and characterization of 3-phosphoglycerate dehydrogenase from peas.
Topics: Alcohol Oxidoreductases; Ethylmaleimide; Glycerophosphates; Hydrogen-Ion Concentration; Kinetics; NAD; NADP; Oxidoreductases; Plants; Serine | 1968 |
Biosynthesis of dihydrosphingosine in vitro.
Topics: Acyltransferases; Alcohol Oxidoreductases; Amino Alcohols; Animals; Ascomycota; Carbon Isotopes; Chromatography, Gas; Chromatography, Thin Layer; Coenzyme A; Endoplasmic Reticulum; Hydrogen-Ion Concentration; In Vitro Techniques; Ketones; Kinetics; Liver; Microsomes; NAD; NADP; Rats; Serine | 1968 |
Biosynthesis of sphingolipid bases. 3. Isolation and characterization of ketonic intermediates in the synthesis of sphingosine and dihydrosphingosine by cell-free extracts of Hansenula ciferri.
Topics: Adenosine Triphosphate; Amino Alcohols; Ascomycota; Autoradiography; Carbon Isotopes; Cell-Free System; Chromatography; Chromatography, Gas; Chromatography, Thin Layer; Coenzyme A; Crystallization; Ethers; Ketones; Lipids; Models, Biological; NADP; Palmitic Acids; Phenylhydrazines; Quaternary Ammonium Compounds; Serine | 1969 |
Studies on the catalytic and regulatory properties of homoserine dehydrogenase of Zea mays roots.
Topics: Alcohol Oxidoreductases; Aminobutyrates; Aspartic Acid; Binding Sites; Cysteine; Hydroxybutyrates; Kinetics; NAD; NADP; Plants; Serine; Zea mays | 1969 |
Reactions of glycine synthesis and glycine cleavage catalyzed by extracts of Arthrobacter globiformis grown on glycine.
Topics: Ammonium Chloride; Arthrobacter; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Cell-Free System; Folic Acid; Formaldehyde; Glutathione; Glycine; Ion Exchange Resins; Kinetics; Mitochondria, Liver; NAD; NADP; Pyridoxal Phosphate; Serine; Sulfhydryl Compounds | 1969 |
Intracellular localization of enzymes in leaves and chloroplast membrane permeability to compounds involved in amino acid syntheses.
Topics: Alanine; Alcohol Oxidoreductases; Amino Acid Oxidoreductases; Amino Acids; Aspartate Aminotransferases; Aspartic Acid; Carbon Dioxide; Chloroplasts; Glutamate Dehydrogenase; Glutamates; Glutathione Reductase; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycine; Isocitrate Dehydrogenase; Malate Dehydrogenase; NAD; NADP; Nicotiana; Oxidoreductases; Plants; Plants, Edible; Plants, Toxic; Pyruvate Kinase; Serine | 1969 |
Synthesis of C18- and C20-dihydrosphingosines, ketodihydrosphingosines, and ceramides by microsomal preparations from mouse brain.
Topics: Amino Alcohols; Animals; Autoradiography; Borates; Brain; Carbon Isotopes; Cerebrosides; Chromatography, Thin Layer; Coenzyme A; Ketones; Lipids; Methods; Mice; Microsomes; NADP; Palmitic Acids; Pyridoxal Phosphate; Serine; Stearic Acids | 1970 |
Hydroxymethylation of the benzene ring. V. NADPH requirement for aryl hydroxymethylation by a C-1 donor bound to a macromolecule.
Topics: Animals; Ascorbic Acid; Benzene; Cell-Free System; Folic Acid; Guinea Pigs; Leucovorin; Microsomes, Liver; NADP; Phenols; Resins, Plant; Serine; Tritium; Vibration | 1970 |
Purification and properties of wheat germ D-3-phosphoglycerate dehydrogenase.
Topics: Acetone; Alcohol Oxidoreductases; Binding Sites; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Computers; Feedback; Glycerophosphates; Kinetics; Methods; NAD; NADP; Plants; Quaternary Ammonium Compounds; Seeds; Serine; Spectrophotometry; Statistics as Topic; Streptomycin; Sulfates; Triticum | 1970 |
Characterization of ferredoxin from nutsedge, Cyperus rotundus L., and other species with a high photosynthetic capacity.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Bacteria; Biological Evolution; Carbon Dioxide; Chlorophyll; Chloroplasts; Cytochromes; Dicarboxylic Acids; Electron Spin Resonance Spectroscopy; Electrophoresis, Disc; Ferredoxins; Glycine; Hydrogen-Ion Concentration; Iron; Molecular Weight; NADP; Pentosephosphates; Peptides; Photochemistry; Photosynthesis; Plant Proteins; Plants; Serine; Species Specificity; Spectrophotometry; Sulfur | 1970 |
Major pathways of glycine and serine catabolism in rat liver.
Topics: Adenosine Triphosphate; Animals; Carbon Dioxide; Carbon Isotopes; Chromatography, Ion Exchange; Folic Acid; Glycine; L-Serine Dehydratase; Liver; Male; Mitochondria, Liver; NADP; Oxidoreductases; Pyruvates; Rats; Serine; Spectrophotometry; Transferases | 1970 |
Biosynthesis of sphingolipid bases. IV. The biosynthetic origin of sphingosine in Hansenula ciferri.
Topics: Amino Alcohols; Animals; Ascomycota; Autoradiography; Carbon Dioxide; Carbon Isotopes; Cattle; Cell-Free System; Chromatography, Thin Layer; Coenzyme A; Depression, Chemical; Fatty Acids; Glycols; Isomerism; Lyases; Models, Chemical; NADP; Palmitic Acids; Quaternary Ammonium Compounds; Serine; Serum Albumin, Bovine; Sphingolipids; Stearic Acids; Stimulation, Chemical | 1971 |
Utilization of ammonium ions for purine precursor synthesis in soluble extracts of Ehrlich ascites cells.
Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Line; Cell-Free System; Deoxyribonucleotides; Diazooxonorleucine; Formates; Glucose; Glutamine; Glycine; Hydrogen-Ion Concentration; Mice; NADP; Neoplasms, Experimental; Nucleic Acids; Nucleotides; Protein Biosynthesis; Purines; Pyrimidines; Quaternary Ammonium Compounds; Ribonucleotides; Serine; Sodium | 1969 |
L-Threonine acetaldehyde-lyase in a strain of Bacillus subtilis.
Topics: Acetates; Aldehyde-Lyases; Bacillus subtilis; Carboxy-Lyases; Chromatography, Gel; Folic Acid; Glycine; Hydrazines; Hydrogen-Ion Concentration; Isoniazid; Kinetics; L-Serine Dehydratase; NAD; NADP; Phosphoric Acids; Pyridoxal Phosphate; Serine; Stereoisomerism; Threonine; Transferases | 1971 |
Biosynthesis of unsaturated sphingolipid bases by microsomal preparations from oysters.
Topics: Amino Alcohols; Animals; Carbon Isotopes; Chromatography, Gas; Coenzyme A; Digestive System; Fatty Acids, Unsaturated; Glycols; Ketones; Mass Spectrometry; Microsomes; NADP; Ostreidae; Palmitic Acids; Serine; Spectrophotometry, Infrared; Sphingolipids; Sphingosine; Stereoisomerism | 1973 |
Properties and physiology of energy-coupled mutants of Escherichia coli.
Topics: Adenosine Triphosphate; Energy Metabolism; Escherichia coli; Glycolysis; Mutation; NAD; NADP; Operon; Serine | 1984 |
Non-hydrolytic release of iron from ferrienterobactin analogs by extracts of Bacillus subtilis.
Topics: Bacillus subtilis; Enterobactin; Flavin Mononucleotide; Hydroxamic Acids; Iron; Iron Chelating Agents; Kinetics; Magnesium; NADP; Oxidation-Reduction; Oxidoreductases; Serine; Siderophores | 1980 |
Lipoamide dehydrogenase from Escherichia coli lacking the redox active disulfide: C44S and C49S. Redox properties of the FAD and interactions with pyridine nucleotides.
Topics: Binding Sites; Coloring Agents; Cysteine; Dihydrolipoamide Dehydrogenase; Disulfides; Electron Transport; Escherichia coli; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; NAD; NADP; Oxidation-Reduction; Phenazines; Serine; Viologens | 1995 |
Site-directed mutagenesis of a serine residue in cinnamyl alcohol dehydrogenase, a plant NADPH-dependent dehydrogenase, affects the specificity for the coenzyme.
Topics: Alcohol Oxidoreductases; Escherichia coli; Eucalyptus; Isoenzymes; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; NAD; NADP; Phenols; Plants, Medicinal; Recombinant Proteins; Serine; Structure-Activity Relationship; Substrate Specificity | 1995 |
Involvement of serine 96 in the catalytic mechanism of ferredoxin-NADP+ reductase: structure--function relationship as studied by site-directed mutagenesis and X-ray crystallography.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Crystallography, X-Ray; DNA Primers; Ferredoxin-NADP Reductase; Flavin-Adenine Dinucleotide; Glycine; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Point Mutation; Protein Conformation; Protein Folding; Recombinant Proteins; Serine; Spectrometry, Fluorescence; Spectrophotometry; Structure-Activity Relationship; Valine | 1995 |
Selective cysteine-->serine replacements in p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens allow the unambiguous assignment of Cys211 as the site of modification by spin-labeled p-chloromercuribenzoate.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Base Sequence; Catalysis; Chloromercuribenzoates; Cysteine; Electron Spin Resonance Spectroscopy; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; p-Chloromercuribenzoic Acid; Pseudomonas fluorescens; Serine; Spin Labels; Structure-Activity Relationship | 1994 |
Characterization of the folate-dependent mitochondrial oxidation of carbon 3 of serine.
Topics: Adenosine Diphosphate; Animals; Carbon Dioxide; Folic Acid; Formates; Formyltetrahydrofolates; Male; Mitochondria, Liver; NADP; Oligomycins; Oxidation-Reduction; Propionates; Rats; Rats, Sprague-Dawley; Serine | 1993 |
Is the NAD(P)H:flavin oxidoreductase from Escherichia coli a member of the ferredoxin-NADP+ reductase family?. Evidence for the catalytic role of serine 49 residue.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Catalysis; DNA Primers; Escherichia coli; Flavins; FMN Reductase; Hydroxyl Radical; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NADH, NADPH Oxidoreductases; NADP; Sequence Alignment; Serine; Threonine | 1996 |
Role of Ser457 of NADPH-cytochrome P450 oxidoreductase in catalysis and control of FAD oxidation-reduction potential.
Topics: Base Sequence; Cytochrome c Group; Dithionite; DNA Primers; Electron Transport; Ferricyanides; Flavin-Adenine Dinucleotide; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADH, NADPH Oxidoreductases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Polymerase Chain Reaction; Serine; Spectrophotometry | 1996 |
The structure of a complex of human 17beta-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors.
Topics: Amino Acid Sequence; Antineoplastic Agents; Binding Sites; Catalysis; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Estradiol; Estradiol Dehydrogenases; Estrone; Female; Humans; Macromolecular Substances; Models, Molecular; Molecular Conformation; Molecular Sequence Data; NADP; Oxidation-Reduction; Oxygen; Placenta; Protein Binding; Protein Conformation; Recombinant Proteins; Serine; Substrate Specificity; Temperature; Tyrosine | 1996 |
Modified ligands to FA and FB in photosystem I. Proposed chemical rescue of a [4Fe-4S] cluster with an external thiolate in alanine, glycine, and serine mutants of PsaC.
Topics: Alanine; Bacterial Proteins; Cytochromes; Cytochromes f; Electron Spin Resonance Spectroscopy; Electron Transport; Glycine; Iron-Sulfur Proteins; Kinetics; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Photosynthetic Reaction Center Complex Proteins; Photosystem I Protein Complex; Serine; Structure-Activity Relationship | 1996 |
Kinetic characterization of wild-type and S229A mutant MurB: evidence for the role of Ser 229 as a general acid.
Topics: Base Sequence; Binding Sites; Carbohydrate Dehydrogenases; Crystallography, X-Ray; DNA Primers; Kinetics; Ligands; Molecular Structure; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Point Mutation; Protons; Serine; Substrate Specificity | 1997 |
Site-directed mutagenesis of the cysteine residues in the Pichia stipitis xylose reductase.
Topics: 4-Chloromercuribenzenesulfonate; Aldehyde Reductase; Binding Sites; Cloning, Molecular; Coenzymes; Cysteine; Enzyme Inhibitors; Mutagenesis, Site-Directed; NAD; NADP; Pichia; Plasmids; Polymerase Chain Reaction; Recombinant Proteins; Recombination, Genetic; Serine; Xylose | 1997 |
The substitution of a single amino acid residue (Ser-116 --> Asp) alters NADP-containing glucose-fructose oxidoreductase of Zymomonas mobilis into a glucose dehydrogenase with dual coenzyme specificity.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Coenzymes; Glucose 1-Dehydrogenase; Glucose Dehydrogenases; Molecular Sequence Data; NADP; Oxidoreductases; Point Mutation; Sequence Alignment; Serine; Substrate Specificity; Zymomonas | 1997 |
Lys42 and Ser42 variants of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens reveal that Arg42 is essential for NADPH binding.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Base Sequence; Binding Sites; Crystallography, X-Ray; Escherichia coli; Gene Expression; Genetic Variation; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; NADP; Oligodeoxyribonucleotides; Protein Conformation; Pseudomonas fluorescens; Recombinant Proteins; Serine; Spectrophotometry | 1998 |
Role of active site tyrosine residues in catalysis by human glutathione reductase.
Topics: Amino Acid Substitution; Binding Sites; Catalysis; Electron Transport; Enzyme Activation; Fluorescence Polarization; Glutathione; Glutathione Reductase; Humans; Leucine; NADP; Oxidation-Reduction; Serine; Spectrometry, Fluorescence; Tyrosine | 1998 |
Coenzyme A-disulfide reductase from Staphylococcus aureus: evidence for asymmetric behavior on interaction with pyridine nucleotides.
Topics: Catalysis; Coenzyme A; Cysteine; Dithionite; Ferricyanides; Isoenzymes; Mass Spectrometry; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Recombinant Proteins; Serine; Spectrometry, Fluorescence; Spectrophotometry; Staphylococcus aureus | 1999 |
Equilibrium analyses of the active-site asymmetry in enterococcal NADH oxidase: role of the cysteine-sulfenic acid redox center.
Topics: Bacterial Proteins; Binding Sites; Coenzymes; Cysteine; Dithionite; Electron Transport; Enzyme Stability; Hydrogen-Ion Concentration; Multienzyme Complexes; Mutagenesis, Site-Directed; NAD; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Recombinant Proteins; Serine; Spectrometry, Fluorescence; Sulfenic Acids | 1999 |
Serine 121 is an essential amino acid for biotin sulfoxide reductase functionality.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Binding Sites; Biotin; Catalysis; Chromatography, High Pressure Liquid; Coenzymes; Conserved Sequence; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Factor Xa; Glutathione Transferase; Guanine Nucleotides; Iron-Sulfur Proteins; Ligands; Mass Spectrometry; Metalloproteins; Molecular Sequence Data; Molybdenum Cofactors; Mutagenesis, Site-Directed; NADP; Oxidative Stress; Oxidoreductases; Oxygen; Paraquat; Pteridines; Pterins; Recombinant Fusion Proteins; Rhodobacter sphaeroides; Sequence Homology, Amino Acid; Serine; Spectrometry, Fluorescence; Threonine; Time Factors | 2000 |
Structural basis for a change in substrate specificity: crystal structure of S113E isocitrate dehydrogenase in a complex with isopropylmalate, Mg2+, and NADP.
Topics: Amino Acid Substitution; Binding Sites; Catalysis; Crystallography, X-Ray; Escherichia coli; Freezing; Glutamic Acid; Isocitrate Dehydrogenase; Macromolecular Substances; Magnesium; Malates; NADP; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Structure-Activity Relationship; Substrate Specificity; Tyrosine | 2001 |
NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer.
Topics: Amino Acid Substitution; Animals; Catalysis; Crystallography, X-Ray; Electron Transport; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Humans; Hydrogen Bonding; Models, Molecular; Mutagenesis, Site-Directed; NADP; NADPH-Ferrihemoprotein Reductase; Niacinamide; Protein Conformation; Rats; Recombinant Proteins; Serine; Spectrophotometry; Tryptophan | 2001 |
The role of serine-246 in cytochrome P450eryF-catalyzed hydroxylation of 6-deoxyerythronolide B.
Topics: Bacterial Proteins; Chromatography, Gas; Cytochrome P-450 Enzyme System; Erythromycin; Hydrogen Peroxide; Hydroxylation; Indicators and Reagents; Kinetics; Mixed Function Oxygenases; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Serine; Spectrophotometry, Ultraviolet | 2001 |
Critical residues for the specificity of cofactors and substrates in human estrogenic 17beta-hydroxysteroid dehydrogenase 1: variants designed from the three-dimensional structure of the enzyme.
Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Binding Sites; Catalytic Domain; Cells, Cultured; Histidine; Humans; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NAD; NADP; Protein Conformation; Serine | 2001 |
Quantification of the influence of HPrSer46P on CcpA-cre interaction.
Topics: Amino Acid Substitution; Bacillus megaterium; Bacterial Proteins; Base Sequence; Blotting, Western; DNA-Binding Proteins; DNA, Bacterial; Electrophoretic Mobility Shift Assay; Fructosediphosphates; Gene Expression Regulation, Bacterial; Glucose-6-Phosphate; Macromolecular Substances; NADP; Operon; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphorylation; Proline; Protein Binding; Repressor Proteins; Response Elements; Serine; Surface Plasmon Resonance; Thermodynamics; Time Factors | 2002 |
Structural and thermodynamic studies on a salt-bridge triad in the NADP-binding domain of glutamate dehydrogenase from Thermotoga maritima: cooperativity and electrostatic contribution to stability.
Topics: Alanine; Arginine; Binding Sites; Crystallography, X-Ray; Cysteine; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Guanidine; Lysine; Mutagenesis, Site-Directed; NADP; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Salts; Serine; Static Electricity; Structure-Activity Relationship; Thermodynamics; Thermotoga maritima; Urea | 2002 |
Calmodulin-dependent and -independent activation of endothelial nitric-oxide synthase by heat shock protein 90.
Topics: Animals; Arginine; Calcium; Calmodulin; Cattle; Cytochrome c Group; Dose-Response Relationship, Drug; HSP90 Heat-Shock Proteins; Immunoblotting; Kinetics; NADH Dehydrogenase; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Precipitin Tests; Protein Processing, Post-Translational; Serine; Time Factors | 2003 |
[Light-dependent incorporation of selenite into selenocysteine by isolated chromatophore of Chromatium vinosum].
Topics: Catalysis; Chromatium; Glutathione; Glutathione Reductase; Light; NADP; Selenocysteine; Serine; Sodium Selenite | 1999 |
Roles of individual amino acids in helix 14 of the membrane domain of proton-translocating transhydrogenase from Escherichia coli as deduced from cysteine mutagenesis.
Topics: Alkaline Phosphatase; Amino Acids; Binding Sites; Cysteine; Escherichia coli; Ethylmaleimide; Glycine; Models, Chemical; Mutagenesis, Site-Directed; Mutation; NAD; NADP; NADP Transhydrogenases; Plasmids; Protein Structure, Tertiary; Protons; Serine | 2003 |
Essential glycine in the proton channel of Escherichia coli transhydrogenase.
Topics: Alanine; Amino Acid Sequence; Catalysis; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glycine; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADP; NADP Transhydrogenases; Protein Conformation; Protein Structure, Tertiary; Protons; Serine | 2003 |
EFFECT OF ENVIRONMENTAL CONDITIONS ON THE NADP-SPECIFIC GLUTAMIC ACID DEHYDROGENASE IN NEUROSPORA CRASSA.
Topics: Amino Acid Oxidoreductases; Ammonium Compounds; Caseins; Glutamates; Glycine; Lysine; NADP; Neurospora; Neurospora crassa; Pharmacology; Proteins; Quaternary Ammonium Compounds; Research; Serine | 1963 |
PLASMA AMINO ACID PATTERNS IN ALCOHOLISM: THE EFFECTS OF ETHANOL LOADING.
Topics: Alanine; Alcoholism; Amino Acids; Autoanalysis; Biomedical Research; Blood; Ethanol; Genetics, Medical; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Methionine; NAD; NADP; Proline; Proteins; Serine; Toxicology; Valine | 1964 |
FVT-1 is a mammalian 3-ketodihydrosphingosine reductase with an active site that faces the cytosolic side of the endoplasmic reticulum membrane.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Animals; Binding Sites; Blotting, Northern; Cell Line; Cell Proliferation; COS Cells; Cytosol; Endopeptidase K; Endoplasmic Reticulum; Escherichia coli; Gene Library; Genotype; HeLa Cells; Humans; Immunoblotting; Intracellular Membranes; Kinetics; Mice; Microscopy, Fluorescence; Models, Biological; Molecular Sequence Data; NADP; Protein Structure, Tertiary; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Sphingolipids; Tissue Distribution; Transfection | 2004 |
The structure of Apo R268A human aldose reductase: hinges and latches that control the kinetic mechanism.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); Alanine; Aldehyde Reductase; Arginine; Base Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; Glycine; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; NADP; Protein Conformation; Serine; Static Electricity; Stereoisomerism; Temperature; Ultraviolet Rays | 2005 |
Identification of amino acids required for the functional up-regulation of human dihydrofolate reductase protein in response to antifolate Treatment.
Topics: Amino Acids; Animals; Binding Sites; Blotting, Western; Catalysis; Cell Survival; CHO Cells; Cloning, Molecular; Cricetinae; Cysteine; DNA Primers; Folic Acid Antagonists; Gene Expression Regulation, Enzymologic; Glutamic Acid; Glutathione Transferase; Green Fluorescent Proteins; Humans; Inhibitory Concentration 50; Kinetics; Leucine; Methotrexate; Microscopy, Fluorescence; Models, Biological; Mutagenesis, Site-Directed; Mutation; NADP; Protein Biosynthesis; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Spectrophotometry; Tetrahydrofolate Dehydrogenase; Time Factors; Transcription, Genetic; Transfection; Up-Regulation | 2005 |
Release of oxidized plastocyanin from photosystem I limits electron transfer between photosystem I and cytochrome b6f complex in vivo.
Topics: Animals; Binding Sites; Chlamydomonas; Cytochrome b6f Complex; Dose-Response Relationship, Drug; Electrons; Glutamic Acid; Glutamine; Kinetics; Mutation; NADP; Oxygen; Phenotype; Photosynthesis; Photosystem I Protein Complex; Plastocyanin; Protein Binding; Serine; Spectrophotometry; Time Factors; Tryptophan | 2005 |
L-Threonine dehydrogenase from the hyperthermophilic archaeon Pyrococcus horikoshii OT3: gene cloning and enzymatic characterization.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Animals; Catalysis; Cloning, Molecular; Hydrogen; Magnetic Resonance Spectroscopy; Molecular Sequence Data; NADP; Pyrococcus horikoshii; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Stereoisomerism; Substrate Specificity | 2005 |
Endothelial cell superoxide anion radical generation is not dependent on endothelial nitric oxide synthase-serine 1179 phosphorylation and endothelial nitric oxide synthase dimer/monomer distribution.
Topics: Animals; Biopterins; Blotting, Western; Cattle; Cells, Cultured; Dimerization; Endothelium, Vascular; HSP90 Heat-Shock Proteins; Immunoprecipitation; NADP; Nitric Oxide Synthase Type III; Phosphorylation; Serine; Superoxides | 2006 |
Structural basis for the alteration of coenzyme specificity in a malate dehydrogenase mutant.
Topics: Bacterial Proteins; Binding Sites; Coenzymes; Crystallization; Hydrogen Bonding; Kinetics; Malate Dehydrogenase; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; NAD; NADP; Protein Binding; Protein Structure, Tertiary; Serine; Thermus | 2006 |
Functional and structural characterization of a thiol peroxidase from Mycobacterium tuberculosis.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Cysteine; Dimerization; Molecular Sequence Data; Molecular Weight; Mutant Proteins; Mutation; Mycobacterium tuberculosis; NADP; Oxidation-Reduction; Peroxidases; Protein Structure, Quaternary; Protein Structure, Secondary; Serine; Solutions | 2006 |
The role of a conserved serine residue within hydrogen bonding distance of FAD in redox properties and the modulation of catalysis by Ca2+/calmodulin of constitutive nitric-oxide synthases.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Calcium; Calmodulin; Catalysis; Electron Transport; Flavin-Adenine Dinucleotide; Humans; Hydrogen Bonding; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADP; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Oxidation-Reduction; Polymerase Chain Reaction; Sequence Homology, Amino Acid; Serine; Threonine | 2006 |
Structural insight into the catalytic mechanism of gluconate 5-dehydrogenase from Streptococcus suis: Crystal structures of the substrate-free and quaternary complex enzymes.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Calcium; Catalytic Domain; Crystallography, X-Ray; Gluconates; Models, Molecular; Molecular Sequence Data; NADP; Oxidoreductases; Protein Structure, Quaternary; Sequence Alignment; Serine; Streptococcus suis | 2009 |
Probing the molecular determinants of coenzyme selectivity in the P450 BM3 FAD/NADPH domain.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Cytochrome P-450 Enzyme System; Flavin-Adenine Dinucleotide; Kinetics; Lysine; Molecular Sequence Data; NADP; NADPH-Ferrihemoprotein Reductase; Protein Structure, Tertiary; Sequence Alignment; Serine | 2009 |
Determination of phosphorylation sites for NADP-specific isocitrate dehydrogenase from mycobacterium tuberculosis.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Catalytic Domain; Computer Simulation; Isocitrate Dehydrogenase; Kinetics; Models, Molecular; Molecular Sequence Data; Mycobacterium tuberculosis; NADP; Phosphorylation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine | 2009 |
SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Nucleus; CHO Cells; Cricetinae; Cricetulus; Glycine Hydroxymethyltransferase; HeLa Cells; Humans; Liver; Mice; Molecular Sequence Data; NADP; NIH 3T3 Cells; Serine; Tetrahydrofolate Dehydrogenase; Thymine Nucleotides | 2009 |
Cysteine as a modulator residue in the active site of xenobiotic reductase A: a structural, thermodynamic and kinetic study.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Coumarins; Cysteine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Protein Conformation; Pseudomonas putida; Serine; Substrate Specificity; Thermodynamics; Xenobiotics | 2010 |
Molecular mechanism of NADPH-glyceraldehyde-3-phosphate dehydrogenase regulation through the C-terminus of CP12 in Chlamydomonas reinhardtii.
Topics: Algorithms; Arginine; Aspartic Acid; Binding Sites; Biocatalysis; Catalytic Domain; Chlamydomonas reinhardtii; Circular Dichroism; Glyceraldehyde-3-Phosphate Dehydrogenases; Kinetics; Models, Molecular; Mutation; NADP; Oxidation-Reduction; Plant Proteins; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Serine; Surface Plasmon Resonance | 2011 |
Redox chemistry of the Schizosaccharomyces pombe ferredoxin electron-transfer domain and influence of Cys to Ser substitutions.
Topics: Amino Acid Substitution; Circular Dichroism; Cysteine; Ferredoxin-NADP Reductase; Ferredoxins; Iron-Sulfur Proteins; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Serine; Thermodynamics | 2011 |
A novel in-gel assay and an improved kinetic assay for determining in vitro sulfite reductase activity in plants.
Topics: Arabidopsis; Gels; Isoenzymes; Kinetics; Molecular Biology; Molecular Sequence Data; NADP; Oxidoreductases Acting on Sulfur Group Donors; Plant Leaves; Plant Proteins; Reproducibility of Results; Serine; Solanum lycopersicum; Substrate Specificity; Tungsten Compounds | 2012 |
Role of Serine140 in the mode of action of Mycobacterium tuberculosis β-ketoacyl-ACP Reductase (MabA).
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Mycobacterium tuberculosis; NADP; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Serine; Spectrometry, Fluorescence; Tuberculosis | 2012 |
Crystallization and preliminary X-ray analysis of L-serine 3-dehydrogenase complexed with NADP+ from the hyperthermophilic archaeon Pyrobaculum calidifontis.
Topics: Crystallization; Crystallography, X-Ray; Electrophoresis, Polyacrylamide Gel; NADP; Oxidoreductases; Pyrobaculum; Serine | 2013 |
Structure of NADP(+)-dependent glutamate dehydrogenase from Escherichia coli--reflections on the basis of coenzyme specificity in the family of glutamate dehydrogenases.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Coenzymes; Crystallography, X-Ray; Escherichia coli; Escherichia coli Proteins; Glutamate Dehydrogenase (NADP+); Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; NADP; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Serine; Static Electricity | 2013 |
Role of Ser-257 in the sliding mechanism of NADP(H) in the reaction catalyzed by the Aspergillus fumigatus flavin-dependent ornithine N5-monooxygenase SidA.
Topics: Amino Acid Substitution; Aspergillus fumigatus; Catalysis; Flavins; Fungal Proteins; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Mutation, Missense; NADP; Serine | 2013 |
Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells.
Topics: Adenosine Triphosphate; Amino Acid Oxidoreductases; Animals; Carrier Proteins; Cell Line, Tumor; Embryonic Stem Cells; Energy Metabolism; Fatty Acids; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Glycine; Humans; Male; Metabolic Flux Analysis; Metabolic Networks and Pathways; Methotrexate; Mice; Multienzyme Complexes; NADP; Neoplasms; Protein Biosynthesis; Purines; Serine; Transferases | 2013 |
Quantitative flux analysis reveals folate-dependent NADPH production.
Topics: Animals; Carbon; Cell Line; Cell Line, Tumor; Cytosol; Folic Acid; Glutathione; Glycine; HEK293 Cells; Humans; Isoenzymes; Leucovorin; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mitochondria; NADP; Oxidation-Reduction; Oxidative Stress; Pentose Phosphate Pathway; Serine; Tetrahydrofolates | 2014 |
Tracing compartmentalized NADPH metabolism in the cytosol and mitochondria of mammalian cells.
Topics: Cell Line, Tumor; Cytosol; Glucose; Glycine; Humans; Isocitrate Dehydrogenase; Metabolic Flux Analysis; Mitochondria; NADP; Serine | 2014 |
Glycolytic flux controls D-serine synthesis through glyceraldehyde-3-phosphate dehydrogenase in astrocytes.
Topics: Adenosine Triphosphate; Allosteric Regulation; Animals; Astrocytes; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Glycolysis; Hippocampus; Humans; Mice; Mice, Inbred ICR; Mice, Knockout; NADP; Racemases and Epimerases; Serine; Synaptic Transmission | 2015 |
In silico model-driven cofactor engineering strategies for improving the overall NADP(H) turnover in microbial cell factories.
Topics: Bacillus subtilis; Bioreactors; Computer Simulation; Enzymes; Escherichia coli; Glycerol; NAD; NADP; Oxidation-Reduction; Pichia; Saccharomyces cerevisiae; Serine | 2015 |
Serine 1179 Phosphorylation of Endothelial Nitric Oxide Synthase Increases Superoxide Generation and Alters Cofactor Regulation.
Topics: Animals; Arginine; Biopterins; Calcium; Calmodulin; Cattle; Cell Survival; Citrulline; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; HEK293 Cells; Humans; Mutation; NADP; Nitric Oxide Synthase Type III; Oxygen; Phosphorylation; Reactive Oxygen Species; Recombinant Proteins; Serine; Spin Trapping; Superoxides; Vascular Endothelial Growth Factor A | 2015 |
Significance of Ser-188 in human mitochondrial NAD kinase as determined by phosphomimetic and phosphoresistant amino-acid substitutions.
Topics: Amino Acid Substitution; Binding Sites; Catalysis; Enzyme Activation; Humans; Mitochondrial Proteins; NADP; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Serine; Structure-Activity Relationship | 2015 |
Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway.
Topics: Aminoimidazole Carboxamide; Carbon; Cell Compartmentation; Cell Proliferation; Colonic Neoplasms; CRISPR-Cas Systems; Cytosol; Folic Acid; Formates; Gene Knockout Techniques; Gene Library; Glycine; Glycine Hydroxymethyltransferase; HCT116 Cells; HEK293 Cells; Humans; Leucovorin; Metabolic Networks and Pathways; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondria; Mutation; NADP; Ribonucleotides; Serine; Xenograft Model Antitumor Assays | 2016 |
Human serine racemase is allosterically modulated by NADH and reduced nicotinamide derivatives.
Topics: Adenosine Triphosphate; Allosteric Site; Binding Sites; Humans; Inhibitory Concentration 50; Kinetics; NAD; NADP; Niacinamide; Protein Binding; Protein Structure, Tertiary; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Serine | 2016 |
Control of Autophagy in Chlamydomonas Is Mediated through Redox-Dependent Inactivation of the ATG4 Protease.
Topics: Autophagy; Chlamydomonas; Conserved Sequence; Cysteine; Disulfides; Enzyme Activation; Light; Models, Biological; Mutation; NADP; Oxidation-Reduction; Plant Proteins; Protein Aggregates; Protein Multimerization; Serine; Stress, Physiological; Structure-Activity Relationship; Thioredoxins | 2016 |
Disruption of De Novo Serine Synthesis in Müller Cells Induced Mitochondrial Dysfunction and Aggravated Oxidative Damage.
Topics: Adenosine Triphosphate; Aged; Chaperonin 60; Ependymoglial Cells; Glutathione; HSP72 Heat-Shock Proteins; Humans; Middle Aged; Mitochondria; NADP; Oxidative Stress; Phosphoglycerate Dehydrogenase; Reactive Oxygen Species; Serine; Up-Regulation | 2018 |
NAD(P)HX repair deficiency causes central metabolic perturbations in yeast and human cells.
Topics: Cells, Cultured; Humans; Metabolic Diseases; Metabolome; NAD; NADP; Racemases and Epimerases; Saccharomyces cerevisiae; Serine | 2018 |
Direct stimulation of NADP
Topics: Animals; Chromatography, Liquid; Cytosol; HEK293 Cells; Humans; Insulin-Like Growth Factor I; Mice; NADP; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Domains; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Tandem Mass Spectrometry | 2019 |
Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation.
Topics: Aminohydrolases; B-Lymphocytes; Cell Transformation, Viral; Epstein-Barr Virus Infections; Epstein-Barr Virus Nuclear Antigens; Female; Folic Acid; Glycolysis; HEK293 Cells; Herpesvirus 4, Human; Humans; Lymphocyte Activation; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondria; Multifunctional Enzymes; NADP; Oxidation-Reduction; Proteome; Proto-Oncogene Proteins c-myc; Serine | 2019 |
Photoprotection by mitochondrial alternative pathway is enhanced at heat but disabled at chilling.
Topics: Arabidopsis; Chlorophyll A; Cold Temperature; Glycine; Hot Temperature; Light; Methacrylates; Mitochondria; Mitochondrial Proteins; Mutation; NADP; Oxidoreductases; Photosynthesis; Plant Leaves; Plant Proteins; Serine; Thiazoles | 2020 |
Alteration of cofactor specificity of the acrylyl-CoA reductase from Escherichia coli.
Topics: Amino Acid Substitution; Arginine; Aspartic Acid; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Mutagenesis, Site-Directed; NAD; NADP; Protein Engineering; Quinone Reductases; Serine; Substrate Specificity | 2021 |
Serine catabolism generates liver NADPH and supports hepatic lipogenesis.
Topics: Acetyl Coenzyme A; Adipose Tissue; Aminohydrolases; Animals; Fatty Acids; Female; Folic Acid; Formate-Tetrahydrofolate Ligase; Glutamine; Glycine Hydroxymethyltransferase; Hepatocytes; Lipid Metabolism; Lipogenesis; Liver; Male; Metabolic Networks and Pathways; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Multienzyme Complexes; NADP; Oxidative Phosphorylation; Oxidoreductases Acting on CH-NH Group Donors; Serine | 2021 |
Loss of peroxisomal NAD kinase 3 (NADK3) affects photorespiration metabolism in Arabidopsis.
Topics: Arabidopsis; Carbon Dioxide; Glycine; NAD; NADP; Serine | 2023 |