serine has been researched along with nad in 133 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 67 (50.38) | 18.7374 |
| 1990's | 21 (15.79) | 18.2507 |
| 2000's | 17 (12.78) | 29.6817 |
| 2010's | 18 (13.53) | 24.3611 |
| 2020's | 10 (7.52) | 2.80 |
| Authors | Studies |
|---|---|
| Dubrow, R; Pizer, LI | 1 |
| Boonstra, J; De Vries, W; Konings, WN | 1 |
| Pizer, LI; Saski, R | 1 |
| Ord, MG; Stocken, LA | 1 |
| Behr, P; Meyer, E; Wurtz, B | 1 |
| Winicov, I | 1 |
| Goldberg, I; Mateles, RI | 1 |
| Fukumaki, Y; Kobayashi, Y; Sakaki, Y; Shirabe, K; Takano, T; Takeshita, M; Yubisui, T | 1 |
| Collier, RJ; Reich, KA; Weinstein, BR; Wilson, BA | 1 |
| Berchtold, GA; Frigo, TB; Quinn, NR; Rusnak, F; Sakaitani, M; Tu, C; Walsh, CT | 1 |
| Huang, AH; Yu, C | 1 |
| Clary, GL; Guynn, RW; LaBaume, LB; Merrill, DK | 1 |
| Clary, GL; Guynn, RW | 1 |
| Kikuchi, G; Yoshida, T | 1 |
| Frisell, WR; Randolph, VM | 1 |
| Chiba, H; Kitagawa, Y; Nakanishi, K; Sugimoto, E | 1 |
| Diamond, LS; Weinbach, EC | 1 |
| Kobayashi, K; Lindros, KO; Okawa, K; Parrilla, R; Williamson, JR; Zimmerman, UJ | 1 |
| Cohen, GN; Truffa-Bachi, P; Veron, M | 1 |
| Yoshida, A | 1 |
| Gascoyne, T; Krebs, HA; Notton, BM | 1 |
| Botsford, JL; Parks, LW | 1 |
| Pizer, LI; Sugimoto, E | 2 |
| Zajac, J | 1 |
| Kikuchi, G; Kochi, H; Sato, N; Sato, T | 1 |
| Gibson, F; Young, IG | 1 |
| Fasella, P; John, RA | 1 |
| Kikuchi, G; Motokawa, Y | 1 |
| Kung, HF; Wagner, C | 1 |
| Bygrave, FL; Williams, ML | 1 |
| Naylor, HB; Nelson, JD | 1 |
| Ballard, FJ | 1 |
| Herman, RH; Rosensweig, NS; Stifel, FB | 1 |
| Thomas, P; Tudball, N | 1 |
| Gregory, EM; Harrison, JH; Rohrbach, MS | 1 |
| Ogur, M; Ulane, R | 1 |
| Pizer, LI; Ponce-de-Leon, MM | 1 |
| Freese, E; Konings, WN; Sheu, CW | 1 |
| Pizer, LI; Regan, JD | 1 |
| Baird, GD; Heitzman, RJ; Hibbitt, KG | 1 |
| Mauron, J; Mottu, F; Spohr, G | 1 |
| Bruin, WJ; Frantz, BM; Sallach, HJ | 1 |
| Pizer, LI; Winicov, I | 1 |
| Cripps, RE; Noble, AS | 1 |
| Kaback, HR; Lombardi, FJ; Reeves, JP; Short, SA | 1 |
| Kaback, HR; Short, SA | 1 |
| Emmens, M; Konings, WN; Kuenen, JG; Matin, A | 1 |
| Battat, E; Goldberg, I; Mateles, RI | 1 |
| Davies, DD; Slaughter, JC | 1 |
| LeKim, D; Sticht, G; Stoffel, W | 1 |
| Bryan, JK | 1 |
| Kikuchi, G; Kochi, H | 1 |
| Santarius, KA; Stocking, CR | 1 |
| Rosenblum, IY; Sallach, HJ | 1 |
| Turner, JM; Willetts, AJ | 1 |
| Booth, IR; Findlay, MJ; Kroll, RG; Rowland, GC; Stewart, LM | 1 |
| Huang, AH; Liang, Z; Yu, C | 1 |
| Roise, D; Soda, K; Walsh, CT; Yagi, T | 1 |
| Horikoshi, K; Kitada, M | 1 |
| Cleland, WW; Cook, PF; Grimshaw, CE | 1 |
| Stenberg, E; Strøm, AR; Styrvold, OB | 1 |
| Hopkins, N; Williams, CH | 2 |
| Baltas, M; Boudet, AM; Douglas, KT; Feuillet, C; Gorrichon, L; Grima-Pettenati, J; Kennedy, K; Lauvergeat, V; McKie, JH | 1 |
| Banaszak, LJ; Grant, GA; Schuller, DJ | 1 |
| Lin, ZP; Nissim, I; States, B; Yudkoff, M | 1 |
| Rout, UK; Weiner, H | 1 |
| Kasper, CB; Shen, AL | 1 |
| Lee, H; Zhang, Y | 1 |
| Gulick, AM; Holden, HM; Thoden, JB | 1 |
| Aghajanian, S; Engel, PC; Goyal, A; Hayden, BM; Wang, XG | 1 |
| Hol, WG; Pizza, M; Rappuoli, R; van den Akker, F | 1 |
| Chait, BT; Erickson, SD; Haller, I; Manning, JM; Martinez del Pozo, A; Petsko, G; Ringe, D; Soda, K; van Ophem, PW; Yoshimura, T | 1 |
| Holden, HM; Thoden, JB | 2 |
| Digits, JA; Hedstrom, L | 1 |
| Boschi-Muller, S; Branlant, G | 1 |
| Claiborne, A; Mallett, TC; Parsonage, D | 1 |
| Hurley, TD; Weiner, H | 1 |
| Abdel-Meguid, SS; Court, RI; Janson, CA; Payne, DJ; Qiu, X; Smyth, MG | 1 |
| Dolan, KM; Lindenmayer, G; Olson, JC | 1 |
| Iyanagi, T; Kimura, S; Nishida, H | 1 |
| Azzi, A; Bellemare, V; Chang, HJ; Huang, YW; Laberge, S; Lin, SX; Pineau, I | 1 |
| Miziorko, HM; Ríos, SE; Runquist, JA; Vinarov, DA | 1 |
| Grant, GA; Hu, Z; Xu, XL | 1 |
| Althage, M; Karlsson, J; Rydström, J | 1 |
| SIU, PM; UMBARGER, HE; UMBARGER, MA | 1 |
| CONTRERAS, E; CROXATTO, R; HUIDOBRO, F | 1 |
| NICHOLAS, DJ; RAO, PS | 1 |
| KRAKOFF, IH | 1 |
| LANGER, BW | 1 |
| POMEROY, LR; ROACH, MK; SIEGEL, FL | 1 |
| ORMSBEE, RA; PEACOCK, MG | 1 |
| FREESE, E; YOSHIDA, A | 1 |
| Barber, MJ; Bewley, MC; Davis, CA; Marohnic, CC; Taormina, D | 1 |
| Baroni, S; Daloiso, PD; De Sole, P; Fasanella, S; Giardina, B; Minucci, A; Neri, P; Persichilli, S; Scribano, D; Zappacosta, B | 1 |
| Fushinobu, S; Kuzuyama, T; Nishiyama, M; Tomita, T | 1 |
| Graeff, R; Hao, Q; Kriksunov, IA; Lee, HC; Liu, Q; Munshi, C | 1 |
| Ju, D; Wang, X; Xie, Y; Xu, H | 1 |
| Hemmi, H; Ito, T; Naka, T; Takahashi, K; Yoshimura, T | 1 |
| Bargues, MD; Depaquit, J; Derakhshandeh-Peykar, P; Ferte, H; Jafari, R; Javadian, E; Kaltenbach, M; Moin-Vaziri, V; Nadim, A; Oshaghi, MA; Rassi, Y; Yaghoobi-Ershadi, MR | 1 |
| Gingerich, S; Krukoff, TL | 1 |
| Burton, RL; Chen, S; Grant, GA; Xu, XL | 1 |
| Hayashi, YK; Matsuda, C; Minami, N; Mitsuhashi, H; Nishino, I; Noguchi, S; Nonaka, I; Shalaby, S | 1 |
| Dickert, F; Dobbek, H; Knauer, SH; Mende, S; Spiegelhauer, O; Ullmann, GM | 1 |
| Chiriac, M; Lupan, I; Palibroda, N; Popa, F; Popescu, O | 1 |
| Brown, G; Evdokimova, E; Flick, R; Gonzalez, CF; Savchenko, A; Singer, A; Tan, K; Tchigvintsev, A; Yakunin, AF | 1 |
| Gamcsik, MP; Holmuhamedov, E; Johnson, CB; Lee, H; Macdonald, JM; Pediaditakis, P; Romney, DA; Tikunov, AP; Wolak, JE | 1 |
| Becker, DF; Henzl, MT; Moxley, MA; Singh, RK; Srivastava, D; Tanner, JJ | 1 |
| Burkholder, TP; Geeganage, S; Gillig, J; Huss, K; Kuo, MS; Lu, ZH; Meier, TI; Parthasarathy, S; Roth, K; Shepard, RL; Smith, MC; Tan, B; Wang, T; Young, DA; Zhai, Y; Zhao, G | 1 |
| Koduru, L; Lakshmanan, M; Lee, DY; Yu, K | 1 |
| Abdalla, AE; Duan, X; Guo, S; Huang, C; Huang, X; Wang, X; Xie, J; Yan, S | 1 |
| Bruno, S; Campanini, B; Dellafiora, L; Faggiano, S; Marchesani, F; Margiotta, M; Mozzarelli, A | 1 |
| Chan, SH; Chen, SD; Chuang, YC; Huang, CW; Lin, JW; Lin, TK; Liou, CW; Zhen, YY | 1 |
| Bahou, WF; Browne, S; Chu, WT; Gnatenko, DV; Li, Z; Mantle, TJ; Nesbitt, NM; Seeliger, MA; Wang, J; Zhang, B | 1 |
| Adiels, M; Barrett, PH; Bjornson, E; Boren, J; Hakkarainen, A; Hallström, BM; Kilicarslan, M; Klevstig, M; Lundbom, J; Lundbom, N; Mardinoglu, A; Marschall, HU; Nielsen, J; Serlie, MJ; Smith, U; Söderlund, S; Ståhlman, M; Taskinen, MR; Uhlén, M; Vergès, B; Watts, GF; Zhang, C | 1 |
| Escalante-Semerena, JC; VanDrisse, CM | 1 |
| Bushel, P; Chandel, N; Grenet, D; Li, J; Lozoya, OA; Martinez-Reyes, I; Santos, JH; Wang, T; Woychik, RP | 1 |
| Becker-Kettern, J; Conrotte, JF; Fiehn, O; Jung, PP; Linster, CL; Paczia, N; Steinmetz, LM; Zhu, C | 1 |
| Clements, DR; Dai, C; Everley, RA; Giacomantonio, MA; Gujar, S; Gygi, SP; Kennedy, BE; Kim, Y; Murphy, JP; Pathak, GP; Paulo, JA; Sharif, T | 1 |
| Khine, CC; Kinoshita, R; Murata, H; Nishikawa, A; Sakaguchi, M; Yamamoto, KI | 1 |
| Becker-Kettern, J; Cifuente, JO; Conrotte, JF; Guerin, ME; Linster, CL; Paczia, N | 1 |
| Chen, Z; Garcia Canaveras, JC; Ghergurovich, JM; Hu, Z; Jang, C; Joshi, S; Liang, L; Mayr, JA; McReynolds, MR; Morscher, RJ; Rabinowitz, JD; Su, X; Wang, L; White, E; Yang, L; Zhan, L; Zhang, Z | 1 |
| Chmielewski, J; Curtis, RW; Das, C; Fu, J; Ghosh, AK; Kinzer-Ursem, TL; Luo, ZQ; Puvar, K; R Nyalapatla, P; Rovira, AR; Saleh, AM; Tor, Y; Wirth, MJ; Zhou, Y | 1 |
| Kanarek, N; Maynard, AG | 1 |
| Chen, J; Chen, X; Gao, W; Hao, B; Huang, M; Huang, W; Li, K; Liu, J; Liu, Q; Liu, R; Shao, Y; Wang, J; Wang, Q; Wei, Z; Xu, P; Xu, Y; Ye, S; Zeng, S; Zhang, H; Zhang, Q; Zhong, Z | 1 |
| Badepally, NG; Singh, A; Surolia, A | 1 |
| But, SY; Khmelenina, VN; Mustakhimov, II; Reshetnikov, AS; Rozova, ON | 1 |
| Chen, X; Hou, Y; Wang, X; Yu, J; Zhao, L; Zhong, B | 1 |
| Chen, Q; Gong, J; He, X; Li, Y; Lin, C; Lou, J; Wu, Y; Zheng, L; Zhu, Y | 1 |
| Ishikawa, T; Kawai-Yamada, M; Kono, M; Miyagi, A; Nagano, M; Noguchi, K; Suzuki, S; Takahara, K; Tanaka, D; Yamaguchi, M | 1 |
| Bajpai, M; Hora, S; Javed, M; Kale, P; Kashyap, M; Maras, JS; Pahwa, P; Ramakrishna, G; Rathore, A; Sarin, SK; Saxena, A; Sevak, JK; Siddiqui, H; Singh, R; Trehanpati, N; Tyagi, S; Yadav, P | 1 |
2 review(s) available for serine and nad
| Article | Year |
|---|---|
Structure, function, and possible origin of a bifunctional allosteric enzyme, Escherichia coli aspartokinase I-homoserine dehydrogenase I.
Topics: Adenosine Triphosphate; Alcohol Oxidoreductases; Allosteric Regulation; Amino Acids; Antigen-Antibody Reactions; Aspartic Acid; Binding Sites; Electrophoresis, Disc; Escherichia coli; Homoserine; Kinetics; Mercaptopurine; Molecular Weight; Multienzyme Complexes; NAD; NADP; Peptide Fragments; Phosphotransferases; Protein Binding; Protein Conformation; Ribonucleotides; Serine; Spectrophotometry; Sulfhydryl Compounds; Threonine | 1974 |
Evaluation of the chemiosmotic interpretation of active transport in bacterial membrane vesicles.
Topics: Benzenesulfonates; Biological Transport, Active; Carbon Radioisotopes; Cell Membrane; Cytochromes; Dinitrophenols; Escherichia coli; Kinetics; Lactose; Lysine; Mercury; NAD; Organoids; Organometallic Compounds; Oxygen Consumption; Potassium; Proline; Rubidium; Serine; Succinates; Tyrosine; Valinomycin | 1974 |
131 other study(ies) available for serine and nad
| Article | Year |
|---|---|
A conformational change in phosphoglycerate dehydrogenase induced by a shift in pH.
Topics: Alcohol Oxidoreductases; Allosteric Regulation; Carbohydrate Dehydrogenases; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; NAD; Protein Binding; Protein Conformation; Serine; Spectrometry, Fluorescence | 1977 |
Amino acid transport in membrane vesicles of obligately anaerobic Veillonella alcalescens.
Topics: Aerobiosis; Aldehyde Oxidoreductases; Amino Acids; Anaerobiosis; Biological Transport, Active; Cell Fractionation; Cell Membrane; Electron Transport; Formates; Fumarates; Glutamates; Glycerolphosphate Dehydrogenase; Glycerophosphates; L-Lactate Dehydrogenase; Lactates; Malate Dehydrogenase; NAD; NADH, NADPH Oxidoreductases; Nitrate Reductases; Nitrates; Pyruvate Dehydrogenase Complex; Serine; Veillonella | 1975 |
Regulatory properties of purified 3-phosphoglycerate dehydrogenase from Bacillus subtilis.
Topics: Alcohol Oxidoreductases; Bacillus subtilis; Carbohydrate Dehydrogenases; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Hydroxymercuribenzoates; Kinetics; Molecular Weight; NAD; Oxidation-Reduction; Serine; Spectrometry, Fluorescence; Streptomycin; Time Factors | 1975 |
Adenosine diphosphate ribosylated histones.
Topics: Adenine; Adenosine Diphosphate Sugars; Animals; Binding Sites; Cell Nucleus; Hepatectomy; Histones; In Vitro Techniques; Liver; Male; NAD; Nucleoside Diphosphate Sugars; Rats; Ribose; Serine; Thymus Gland | 1977 |
[The endogenous metabolism of Pseudomonas fluorescens in relation to the oxidation of ethanol, serine, and pyruvate].
Topics: Ethanol; NAD; Oxidation-Reduction; Oxygen Consumption; Pseudomonas fluorescens; Pyruvates; Serine | 1976 |
The mechanism of end product inhibition of serine biosynthesis. V. Mechanism of serim inhibition of phosphoglycerate dehydrogenases.
Topics: Alcohol Oxidoreductases; Deuterium; Escherichia coli; Glyceric Acids; Hydrogen-Ion Concentration; NAD; Organophosphorus Compounds; Protein Binding; Serine; Thermodynamics | 1975 |
Growth of Pseudomonas C on C1 compounds: enzyme activites in extracts of Pseudomonas C cells grown on methanol, formaldehyde, and formate as sole carbon sources.
Topics: Alcohol Oxidoreductases; Cell Fractionation; Cell-Free System; Chromatography, Gas; Formaldehyde; Formates; Glucose; Glyceric Acids; Hexosephosphates; Hexoses; Ligases; Methanol; NAD; NADP; Oxidation-Reduction; Pseudomonas; Serine; Spectrophotometry | 1975 |
Structural role of serine 127 in the NADH-binding site of human NADH-cytochrome b5 reductase.
Topics: Base Sequence; Binding Sites; Cytochrome Reductases; Cytochrome-B(5) Reductase; Enzyme Stability; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Oligonucleotide Probes; Oxidation-Reduction; Plasmids; Recombinant Proteins; Restriction Mapping; Serine; Thermodynamics | 1991 |
Active-site mutations of diphtheria toxin: effects of replacing glutamic acid-148 with aspartic acid, glutamine, or serine.
Topics: Adenosine Diphosphate Ribose; Affinity Labels; Aspartic Acid; Base Sequence; Binding Sites; Diphtheria Toxin; Glutamates; Glutamic Acid; Glutamine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Serine; Substrate Specificity | 1990 |
Mechanistic studies on trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (Ent A) in the biosynthesis of the iron chelator enterobactin.
Topics: Binding Sites; Enterobacteriaceae; Enterobactin; Escherichia coli Proteins; Kinetics; Models, Chemical; Molecular Structure; NAD; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Serine; Stereoisomerism | 1990 |
Conversion of serine to glycerate in intact spinach leaf peroxisomes: role of malate dehydrogenase.
Topics: Glyceric Acids; Malate Dehydrogenase; Microbodies; NAD; Oxidation-Reduction; Plants; Pyruvates; Serine | 1986 |
Effect of acute ethanol on serine biosynthesis in liver.
Topics: Alcoholic Intoxication; Animals; Cells, Cultured; Ethanol; Glucose; Kinetics; Liver; Male; NAD; Rabbits; Serine | 1987 |
Gluconeogenesis from serine in rabbit hepatocytes.
Topics: Animals; Cells, Cultured; Gluconeogenesis; Lactates; Lactic Acid; Liver; Male; NAD; Pyruvates; Pyruvic Acid; Rabbits; Serine; Urea | 1987 |
Significance of the glycine cleavage system in glycine and serine catabolism in avian liver.
Topics: Ammonium Chloride; Animals; Arylformamidase; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Chickens; Columbidae; Cycloserine; Cysteine; Enzyme Activation; Folic Acid; Glycine; Hydroxylamines; Hypoxanthines; L-Serine Dehydratase; Liver; Male; Mitochondria, Liver; NAD; NADP; Oxidoreductases; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Semicarbazides; Serine; Species Specificity; Subcellular Fractions; Transferases; Uric Acid | 1971 |
Effect of adenine nucleotides on the oxidation of methyl groups in liver mitochondria.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Carbon Dioxide; Dinitrophenols; Folic Acid; Formaldehyde; Formates; Glycine; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methylation; Mitochondria, Liver; Mitochondrial Swelling; NAD; NADP; Oxygen Consumption; Rats; Rotenone; Sarcosine; Semicarbazides; Serine | 1973 |
Purification and properties of beef liver D-glycerate dehydrogenase.
Topics: Alcohol Oxidoreductases; Animals; Cattle; Electrophoresis; Enzyme Activation; Fructosephosphates; Glyceric Acids; Liver; Molecular Weight; NAD; NADP; Pyruvates; Serine; Spectrophotometry; Ultracentrifugation | 1972 |
Entamoeba histolytica. I. Aerobic metabolism.
Topics: Aerobiosis; Catalase; Chloromercuribenzoates; Cinnamates; Citric Acid Cycle; Culture Media; Cyanides; Entamoeba histolytica; Ethanol; Fructose; Galactose; Glucose; Hydrogen-Ion Concentration; Iodoacetates; Metronidazole; NAD; NADP; Oxygen Consumption; Preservation, Biological; Serine; Sulfhydryl Compounds; Vitamin K | 1974 |
Functional compartmentation of acetaldehyde oxidation in rat liver.
Topics: Acetaldehyde; Acetates; Aldehyde Oxidoreductases; Animals; Biological Transport; Carbon Radioisotopes; Ethanol; Flavins; Glucose; Lactates; Liver; Male; NAD; NADP; Oleic Acids; Oxygen Consumption; Perfusion; Pyrazoles; Pyruvates; Rats; Serine; Spectrometry, Fluorescence; Time Factors | 1974 |
Micromethod for the quantitative determination of L-alanine.
Topics: Alanine; Aminobutyrates; Cysteine; Isoleucine; Kinetics; Microchemistry; NAD; Serine; Spectrum Analysis; Valine | 1965 |
Generation of extramitochondrial reducing power in gluconeogenesis.
Topics: Alcohol Oxidoreductases; Animals; Aspartic Acid; Cytoplasm; Ethanol; Gluconeogenesis; In Vitro Techniques; Kidney; Lactates; Liver; Mice; NAD; Oxaloacetates; Pyruvates; Rats; Serine | 1967 |
Role of S-adenosylmethionine in methionine biosynthesis in yeast.
Topics: Adenine Nucleotides; Carbon Isotopes; Cell-Free System; Culture Media; Escherichia coli; Ethanol; Flavin-Adenine Dinucleotide; Hexosephosphates; Homocysteine; Magnesium; Methionine; NAD; Nucleosides; Pyridoxal Phosphate; Saccharomyces; Serine | 1967 |
The mechanism of end product inhibition of serine biosynthesis. II. Optical studies of phosphoglycerate dehydrogenase.
Topics: Alcohol Oxidoreductases; Binding Sites; Fluorescence; Glyceric Acids; Models, Chemical; NAD; Nucleotides; Optical Rotatory Dispersion; Phosphates; Pyridines; Pyruvates; Serine; Spectrum Analysis; Ultraviolet Rays | 1968 |
Phosphorylation of protein in liver and kidney mitochondria of the rat.
Topics: Adenine Nucleotides; Animals; Arsenic; Depression, Chemical; Dinitrophenols; Guanine Nucleotides; Hexokinase; Histidine; Hydrogen-Ion Concentration; Kidney; Maleates; Malonates; Mitochondria; Mitochondria, Liver; Models, Biological; NAD; Oxidative Phosphorylation; Phosphates; Phosphorus Isotopes; Proteins; Rats; Serine; Stimulation, Chemical; Time Factors | 1968 |
Glycine metabolism by rat liver mitochondria. 3. The glycine cleavage and the exchange of carboxyl carbon of glycine with bicarbonate.
Topics: Ammonia; Animals; Arsenic; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Folic Acid; Glycine; In Vitro Techniques; Kinetics; Mitochondria, Liver; NAD; Pyridoxal Phosphate; Rats; Serine; Sulfhydryl Compounds; Transferases | 1969 |
Regulation of the enzymes involved in the biosynthesis of 2,3-dihydroxybenzoic acid in Aerobacter aerogenes and Escherichia coli.
Topics: Benzoates; Cell-Free System; Chromatography, Ion Exchange; Cyclohexanecarboxylic Acids; Enterobacter; Enzyme Repression; Escherichia coli; Hydrogen-Ion Concentration; Iron; Isomerases; Lyases; Magnesium; NAD; Oxidoreductases; Serine; Stimulation, Chemical | 1969 |
The reaction of L-serine O-sulfate with aspartate aminotransferase.
Topics: Alcohol Oxidoreductases; Animals; Aspartate Aminotransferases; Binding Sites; Chemical Phenomena; Chemistry; Dialysis; Fluorometry; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Malates; Myocardium; NAD; Protons; Pyridoxal Phosphate; Pyruvates; Quaternary Ammonium Compounds; Serine; Spectrophotometry; Sulfates; Swine | 1969 |
Glycine metabolism by rat liver mitochondria. IV. Isolation and characterization of hydrogen carrier protein, an essential factor for glycine metabolism.
Topics: Alcohols; Ammonia; Animals; Benzoates; Bicarbonates; Carbon Isotopes; Chromatography, DEAE-Cellulose; Chromatography, Gel; Drug Stability; Electron Transport; Electrophoresis, Disc; Ethylmaleimide; Glycine; Hydrogen; Hydrogen-Ion Concentration; Male; Methods; Mitochondria, Liver; Molecular Weight; NAD; Protein Binding; Proteins; Rats; Serine; Sulfur | 1969 |
The enzymatic synthesis of N-methylalanine.
Topics: Adenosine Triphosphate; Alanine; Amines; Autoradiography; Carbon Isotopes; Chromatography, Gel; Chromatography, Thin Layer; Crystallization; Electrophoresis; Folic Acid; Glutamates; Magnesium; NAD; Paper; Pseudomonas; Pyruvates; Serine | 1970 |
Incorporation of inorganic phosphate into phospholipids by the homogenate and by sub-cellular fractions of rat liver.
Topics: Animals; Antimycin A; Choline; Cytoplasm; Cytosine Nucleotides; Fructose; Hexosephosphates; In Vitro Techniques; Liver; Male; Microsomes, Liver; Mitochondria, Liver; NAD; Oligomycins; Oxidative Phosphorylation; Phosphates; Phospholipids; Phosphorus Isotopes; Rats; Serine | 1970 |
Control of serine biosynthesis in Micrococcus lysodeikticus: inhibition of phosphoglyceric acid dehydrogenase.
Topics: Adenine Nucleotides; Calcium; Carbon Isotopes; Cell-Free System; Edetic Acid; Glycerol; Glycerolphosphate Dehydrogenase; Glycerophosphates; Glycine; Magnesium; Manganese; Micrococcus; NAD; Quaternary Ammonium Compounds; Serine; Stereoisomerism; Sulfates; Zinc | 1971 |
Regulation of gluconeogenesis during exposure of young rats to hypoxic conditions.
Topics: Acetoacetates; Adenine Nucleotides; Adenosine Triphosphate; Animals; Aspartic Acid; Gluconeogenesis; Glucose; Glycogen; Hydroxybutyrates; Hypoxia; Lactates; Liver; Mitochondria, Liver; NAD; Pyruvates; Rats; Serine; Time Factors | 1971 |
Dietary regulation of glycolytic enzymes. XI. Effect of inhibitors of protein synthesis on the adaptation of certain jejunal glycolytic and folate-metabolizing enzymes to diet and sex steroids.
Topics: Aldehyde-Lyases; Animals; Caseins; Dactinomycin; Dietary Carbohydrates; Dietary Proteins; Enzyme Induction; Estradiol; Ethionine; Fasting; Female; Folic Acid; Fructose; Fructosephosphates; Glycolysis; Jejunum; Male; Metabolism; NAD; Oxidoreductases; Pyruvate Kinase; Rats; RNA; Serine; Testosterone; Time Factors; Transferases | 1971 |
The inhibition of glutamate dehydrogenase by L-serine O-sulphate and related compounds and by photo-oxidation in the presence of Rose Bengal.
Topics: Adenosine Diphosphate; Amino Acids; Dialysis; Enzyme Activation; Esters; Glutamate Dehydrogenase; Glutamates; Guanosine Triphosphate; Histidine; Hydrogen-Ion Concentration; NAD; Photochemistry; Rose Bengal; Serine; Time Factors | 1971 |
Characterization of porcine malate dehydrogenase. I. An active center peptide.
Topics: Acetamides; Amino Acid Sequence; Animals; Binding Sites; Carbon Isotopes; Carboxypeptidases; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cysteine; Dansyl Compounds; Glycine; Histidine; Iodoacetates; Kinetics; Malate Dehydrogenase; Methionine; Mitochondria, Muscle; Myocardium; NAD; Peptides; Pronase; Serine; Swine; Threonine | 1971 |
Genetic and physiological control of serine and glycine biosynthesis in Saccharomyces.
Topics: Acetates; Alanine; Ammonium Sulfate; Aspartic Acid; Carbon Isotopes; Cell-Free System; Chemical Precipitation; Chromatography, Paper; Culture Media; Fluorides; Genetics, Microbial; Glucose; Glutamates; Glycerolphosphate Dehydrogenase; Glycerophosphates; Glycine; Glycolysis; Glyoxylates; Isocitrates; Lyases; Mutation; NAD; Oxidative Phosphorylation; Saccharomyces; Serine; Spectrophotometry; Transferases | 1972 |
Serine biosynthesis and its regulation in Bacillus subtilis.
Topics: Ammonium Sulfate; Bacillus subtilis; Carbon Isotopes; Cell-Free System; Chemical Precipitation; Chromatography, Ion Exchange; Culture Media; Fluorometry; Genetics, Microbial; Glycerophosphates; Hot Temperature; Mutation; NAD; Oxidoreductases; Phosphates; Phosphoric Monoester Hydrolases; Serine; Spectrophotometry; Stereoisomerism | 1972 |
Effects of acetate and other short-chain fatty acids on sugar and amino acid uptake of Bacillus subtilis.
Topics: Acetates; Amino Acids; Aminobutyrates; Bacillus subtilis; Carbohydrate Metabolism; Carbon Isotopes; Carrier Proteins; Cell Membrane; Culture Media; Cytochromes; Dinitrophenols; Electron Transport; Fatty Acids; Fructose; Glycosides; NAD; Oxidation-Reduction; Serine; Spectrophotometry; Stereoisomerism; Tritium; Uncoupling Agents | 1972 |
Basis for the serine requirement in leukemic and normal human leukocytes. Reduced levels of the enzymes in the phosphorylated pathway.
Topics: Carbon Isotopes; Carcinoma; Cell Line; Fibroblasts; Glycerolphosphate Dehydrogenase; HeLa Cells; Humans; Leukemia; Leukemia, Myeloid; Leukocytes; Mouth Neoplasms; NAD; Oxidative Phosphorylation; Phosphoric Monoester Hydrolases; Phosphorus Isotopes; Serine | 1972 |
Effects of starvation on intermediary metabolism in the lactating cow. A comparison with metabolic changes occurring during bovine ketosis.
Topics: Acidosis; Adenosine Triphosphate; Animals; Blood Glucose; Cattle; Cattle Diseases; Citrates; Fatty Acids, Nonesterified; Female; Glucose; Glycogen; Ketone Bodies; Lactation; Leucine; Liver; NAD; Oxaloacetates; Phosphoenolpyruvate; Pregnancy; Serine; Starvation | 1972 |
Reciprocal induction and repression of serine dehydratase and phosphoglycerate dehydrogenase by proteins and dietary-essential amino acids in rat liver.
Topics: Alcohol Oxidoreductases; Amino Acids; Animals; Caseins; Dietary Proteins; Egg Proteins; Enzyme Induction; Enzyme Repression; Glutens; Glyceric Acids; L-Serine Dehydratase; Liver; Male; Methionine; Models, Biological; NAD; Organophosphorus Compounds; Protein Biosynthesis; Rats; Serine; Threonine; Tryptophan; Valine | 1973 |
The occurrence of a glycine cleavage system in mammalian brain.
Topics: Animals; Brain; Carbon Dioxide; Carbon Isotopes; Cats; Cattle; Digitonin; Dithiothreitol; Dogs; Enzyme Activation; Glycine; Male; Mitochondria; Multienzyme Complexes; NAD; Pyridoxal Phosphate; Rabbits; Rats; Serine; Subcellular Fractions; Swine; Tetrahydrofolates | 1973 |
The mechanism of end product inhibition of serine biosynthesis. IV. Subunit structure of phosphoglycerate dehydrogenase and steady state kinetic studies of phosphoglycerate oxidation.
Topics: Alcohol Oxidoreductases; Alkylation; Amino Acids; Binding Sites; Carbon Radioisotopes; Crystallization; Electrophoresis; Electrophoresis, Disc; Escherichia coli; Glyceric Acids; Kinetics; Macromolecular Substances; NAD; Organophosphorus Compounds; Oxidation-Reduction; Peptide Fragments; Pyridines; Serine; Spectrometry, Fluorescence; Temperature; Trypsin; Tryptophan | 1974 |
The metabolism of nitrilotriacetate by a pseudomonad.
Topics: Acetates; Alcohol Oxidoreductases; Amino Acids; Anaerobiosis; Carboxy-Lyases; Cell-Free System; Culture Media; Detergents; Dicarboxylic Acids; Glucose; Glyceric Acids; Glycine; Glyoxylates; Ligases; Magnesium; NAD; Nitrilotriacetic Acid; Oxaloacetates; Oxidation-Reduction; Oxygen; Pseudomonas; Pyruvates; Serine; Tetrahydrofolates; Thiamine Pyrophosphate; Transaminases; Transferases | 1973 |
Amino acid transport and staphylococcal membrane vesicles.
Topics: Amino Acids; Amobarbital; Anaerobiosis; Arsenates; Carbon Radioisotopes; Cell Membrane; Chloromercuribenzoates; Cyanides; Depression, Chemical; Electron Transport; Ethylmaleimide; Glycerophosphates; Kinetics; Lactates; Lysostaphin; NAD; Nitrobenzenes; Oxalates; Protoplasts; Serine; Staphylococcus; Threonine | 1974 |
Active transport of amino acids by membrane vesicles of Thiobacillus neapolitanus.
Topics: Amobarbital; Azides; Biological Transport, Active; Cell Membrane; Culture Media; Cyanides; Electron Transport; Glycine; Kinetics; Lactates; Leucine; NAD; Radioisotopes; Serine; Succinates; Thiobacillus; Thiosulfates; Threonine | 1974 |
Growth of Pseudomonas C on C1 compounds: continuoous culture.
Topics: Aminobenzoates; Carbon Dioxide; Carbon Radioisotopes; Folic Acid; Formaldehyde; Formates; Glycine; Methanol; NAD; Polysorbates; Pseudomonas; Serine | 1974 |
The mechanism of end product inhibition of serine biosynthesis. I. Purification and kinetics of phosphoglycerate dehydrogenase.
Topics: Alcohol Oxidoreductases; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Electrophoresis; Escherichia coli; Glyceric Acids; Hydrogen-Ion Concentration; Kinetics; NAD; NADP; Phosphates; Pyruvates; Serine; Streptomycin; Ultracentrifugation | 1968 |
The isolation and characterization of 3-phosphoglycerate dehydrogenase from peas.
Topics: Alcohol Oxidoreductases; Ethylmaleimide; Glycerophosphates; Hydrogen-Ion Concentration; Kinetics; NAD; NADP; Oxidoreductases; Plants; Serine | 1968 |
Biosynthesis of dihydrosphingosine in vitro.
Topics: Acyltransferases; Alcohol Oxidoreductases; Amino Alcohols; Animals; Ascomycota; Carbon Isotopes; Chromatography, Gas; Chromatography, Thin Layer; Coenzyme A; Endoplasmic Reticulum; Hydrogen-Ion Concentration; In Vitro Techniques; Ketones; Kinetics; Liver; Microsomes; NAD; NADP; Rats; Serine | 1968 |
Studies on the catalytic and regulatory properties of homoserine dehydrogenase of Zea mays roots.
Topics: Alcohol Oxidoreductases; Aminobutyrates; Aspartic Acid; Binding Sites; Cysteine; Hydroxybutyrates; Kinetics; NAD; NADP; Plants; Serine; Zea mays | 1969 |
Reactions of glycine synthesis and glycine cleavage catalyzed by extracts of Arthrobacter globiformis grown on glycine.
Topics: Ammonium Chloride; Arthrobacter; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Cell-Free System; Folic Acid; Formaldehyde; Glutathione; Glycine; Ion Exchange Resins; Kinetics; Mitochondria, Liver; NAD; NADP; Pyridoxal Phosphate; Serine; Sulfhydryl Compounds | 1969 |
Intracellular localization of enzymes in leaves and chloroplast membrane permeability to compounds involved in amino acid syntheses.
Topics: Alanine; Alcohol Oxidoreductases; Amino Acid Oxidoreductases; Amino Acids; Aspartate Aminotransferases; Aspartic Acid; Carbon Dioxide; Chloroplasts; Glutamate Dehydrogenase; Glutamates; Glutathione Reductase; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycine; Isocitrate Dehydrogenase; Malate Dehydrogenase; NAD; NADP; Nicotiana; Oxidoreductases; Plants; Plants, Edible; Plants, Toxic; Pyruvate Kinase; Serine | 1969 |
Purification and properties of wheat germ D-3-phosphoglycerate dehydrogenase.
Topics: Acetone; Alcohol Oxidoreductases; Binding Sites; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Computers; Feedback; Glycerophosphates; Kinetics; Methods; NAD; NADP; Plants; Quaternary Ammonium Compounds; Seeds; Serine; Spectrophotometry; Statistics as Topic; Streptomycin; Sulfates; Triticum | 1970 |
L-Threonine acetaldehyde-lyase in a strain of Bacillus subtilis.
Topics: Acetates; Aldehyde-Lyases; Bacillus subtilis; Carboxy-Lyases; Chromatography, Gel; Folic Acid; Glycine; Hydrazines; Hydrogen-Ion Concentration; Isoniazid; Kinetics; L-Serine Dehydratase; NAD; NADP; Phosphoric Acids; Pyridoxal Phosphate; Serine; Stereoisomerism; Threonine; Transferases | 1971 |
Properties and physiology of energy-coupled mutants of Escherichia coli.
Topics: Adenosine Triphosphate; Energy Metabolism; Escherichia coli; Glycolysis; Mutation; NAD; NADP; Operon; Serine | 1984 |
Conversion of glycerate to serine in intact spinach leaf peroxisomes.
Topics: Alanine; Alcohol Oxidoreductases; Biotransformation; Chemical Phenomena; Chemistry; Glyceric Acids; Hydrogen-Ion Concentration; Hydroxypyruvate Reductase; Kinetics; Microbodies; NAD; Oxaloacetates; Plants; Serine | 1984 |
Inactivation of the Pseudomonas striata broad specificity amino acid racemase by D and L isomers of beta-substituted alanines: kinetics, stoichiometry, active site peptide, and mechanistic studies.
Topics: Alanine; Amino Acid Isomerases; Amino Acids; beta-Alanine; Binding Sites; Borates; Isomerism; Kinetics; Molecular Weight; NAD; Pseudomonas; Pyridoxal Phosphate; Serine; Trypsin | 1984 |
Sodium-ion stimulated amino acid uptake in membrane vesicles of alkalophilic Bacillus no. 8-1.
Topics: Amino Acids; Ascorbic Acid; Bacillus; Biological Transport, Active; Cell Membrane; Hydrogen-Ion Concentration; Methylphenazonium Methosulfate; NAD; Oxidation-Reduction; Serine; Sodium | 1980 |
Use of isotope effects and pH studies to determine the chemical mechanism of Bacillus subtilis L-alanine dehydrogenase.
Topics: Alanine; Alanine Dehydrogenase; Amino Acid Oxidoreductases; Bacillus subtilis; Chemical Phenomena; Chemistry, Physical; Deuterium; Hydrogen-Ion Concentration; Mathematics; NAD; Serine | 1981 |
Trimethylamine oxide respiration in Proteus sp. strain NTHC153: electron transfer-dependent phosphorylation and L-serine transport.
Topics: Adenosine Triphosphate; Biological Transport; Electron Transport; Formates; Methylamines; NAD; Oxidation-Reduction; Phosphorylation; Proteus; Serine | 1982 |
Characterization of lipoamide dehydrogenase from Escherichia coli lacking the redox active disulfide: C44S and C49S.
Topics: Cysteine; Dihydrolipoamide Dehydrogenase; Disulfides; Escherichia coli; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; NAD; Oxidation-Reduction; Serine; Spectrometry, Fluorescence; Spectrophotometry; Sulfhydryl Compounds | 1995 |
Lipoamide dehydrogenase from Escherichia coli lacking the redox active disulfide: C44S and C49S. Redox properties of the FAD and interactions with pyridine nucleotides.
Topics: Binding Sites; Coloring Agents; Cysteine; Dihydrolipoamide Dehydrogenase; Disulfides; Electron Transport; Escherichia coli; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; NAD; NADP; Oxidation-Reduction; Phenazines; Serine; Viologens | 1995 |
Site-directed mutagenesis of a serine residue in cinnamyl alcohol dehydrogenase, a plant NADPH-dependent dehydrogenase, affects the specificity for the coenzyme.
Topics: Alcohol Oxidoreductases; Escherichia coli; Eucalyptus; Isoenzymes; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; NAD; NADP; Phenols; Plants, Medicinal; Recombinant Proteins; Serine; Structure-Activity Relationship; Substrate Specificity | 1995 |
The allosteric ligand site in the Vmax-type cooperative enzyme phosphoglycerate dehydrogenase.
Topics: Allosteric Site; Bacterial Proteins; Base Sequence; Binding Sites; Carbohydrate Dehydrogenases; Catalysis; Computer Simulation; Crystallography, X-Ray; Escherichia coli; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Motion; NAD; Phosphoglycerate Dehydrogenase; Protein Conformation; Protons; Recombinant Fusion Proteins; Serine | 1995 |
pH and hormonal regulation of ammoniagenesis in cultured OK cells.
Topics: Ammonia; Animals; Cell Line; Glutamine; Hormones; Hydrogen-Ion Concentration; Kidney; NAD; Opossums; Serine | 1994 |
Involvement of serine 74 in the enzyme-coenzyme interaction of rat liver mitochondrial aldehyde dehydrogenase.
Topics: Adenosine Diphosphate Ribose; Aldehyde Dehydrogenase; Animals; Coenzymes; Enzyme Stability; Esterases; Kinetics; Mitochondria, Liver; Mutation; NAD; Rats; Recombinant Proteins; Sepharose; Serine; Substrate Specificity | 1994 |
Role of Ser457 of NADPH-cytochrome P450 oxidoreductase in catalysis and control of FAD oxidation-reduction potential.
Topics: Base Sequence; Cytochrome c Group; Dithionite; DNA Primers; Electron Transport; Ferricyanides; Flavin-Adenine Dinucleotide; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADH, NADPH Oxidoreductases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Polymerase Chain Reaction; Serine; Spectrophotometry | 1996 |
Site-directed mutagenesis of the cysteine residues in the Pichia stipitis xylose reductase.
Topics: 4-Chloromercuribenzenesulfonate; Aldehyde Reductase; Binding Sites; Cloning, Molecular; Coenzymes; Cysteine; Enzyme Inhibitors; Mutagenesis, Site-Directed; NAD; NADP; Pichia; Plasmids; Polymerase Chain Reaction; Recombinant Proteins; Recombination, Genetic; Serine; Xylose | 1997 |
Molecular structures of the S124A, S124T, and S124V site-directed mutants of UDP-galactose 4-epimerase from Escherichia coli.
Topics: Alanine; Binding Sites; Crystallography, X-Ray; Escherichia coli; Glucose; Macromolecular Substances; Mutagenesis, Site-Directed; NAD; Serine; Substrate Specificity; Threonine; UDPglucose 4-Epimerase; Uridine Diphosphate; Valine | 1997 |
Intersubunit communication in hybrid hexamers of K89L/A163G/S380A and C320S mutants of glutamate dehydrogenase from Clostridium symbiosum.
Topics: Alanine; Allosteric Regulation; Clostridium; Dithionitrobenzoic Acid; Glutamate Dehydrogenase; Glutamic Acid; Lysine; NAD; Protein Conformation; Protein Denaturation; Protein Folding; Recombinant Proteins; Serine | 1997 |
Crystal structure of a non-toxic mutant of heat-labile enterotoxin, which is a potent mucosal adjuvant.
Topics: Adjuvants, Immunologic; Bacterial Toxins; Bacterial Vaccines; Binding Sites; Crystallization; Crystallography, X-Ray; Enterotoxins; Escherichia coli Proteins; Lysine; Models, Molecular; Molecular Structure; Mucous Membrane; Mutagenesis; NAD; Protein Conformation; Protein Engineering; Serine; Structure-Activity Relationship | 1997 |
Substrate inhibition of D-amino acid transaminase and protection by salts and by reduced nicotinamide adenine dinucleotide: isolation and initial characterization of a pyridoxo intermediate related to inactivation.
Topics: Alanine; Catalysis; Chromatography, High Pressure Liquid; D-Alanine Transaminase; Enzyme Inhibitors; NAD; Pyridoxal Phosphate; Pyridoxamine; Pyruvic Acid; Salts; Serine; Transaminases | 1998 |
Dramatic differences in the binding of UDP-galactose and UDP-glucose to UDP-galactose 4-epimerase from Escherichia coli.
Topics: Alanine; Binding Sites; Crystallography, X-Ray; Escherichia coli; Models, Molecular; Mutagenesis, Insertional; NAD; Phenylalanine; Serine; Tyrosine; UDPglucose 4-Epimerase; Uridine Diphosphate Galactose; Uridine Diphosphate Glucose | 1998 |
Kinetic mechanism of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase.
Topics: Amino Acid Substitution; Animals; Binding Sites; Cysteine; Deuterium; Humans; IMP Dehydrogenase; Kinetics; Ligands; Models, Chemical; Mutagenesis, Site-Directed; Mycophenolic Acid; NAD; Protein Binding; Serine; Spectrometry, Fluorescence; Thermodynamics; Tritrichomonas foetus | 1999 |
The active site of phosphorylating glyceraldehyde-3-phosphate dehydrogenase is not designed to increase the nucleophilicity of a serine residue.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; Enzyme Activation; Esters; Geobacillus stearothermophilus; Glyceraldehyde 3-Phosphate; Glyceraldehyde-3-Phosphate Dehydrogenases; Hot Temperature; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; NAD; Phosphorylation; Protease Inhibitors; Serine; Tosyl Compounds | 1999 |
Equilibrium analyses of the active-site asymmetry in enterococcal NADH oxidase: role of the cysteine-sulfenic acid redox center.
Topics: Bacterial Proteins; Binding Sites; Coenzymes; Cysteine; Dithionite; Electron Transport; Enzyme Stability; Hydrogen-Ion Concentration; Multienzyme Complexes; Mutagenesis, Site-Directed; NAD; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Recombinant Proteins; Serine; Spectrometry, Fluorescence; Sulfenic Acids | 1999 |
Evaluation of the roles of the conserved residues of aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Amino Acid Sequence; Arginine; Binding Sites; Conserved Sequence; Glutamic Acid; Humans; Kinetics; Mutagenesis; NAD; Recombinant Fusion Proteins; Serine; Threonine | 1999 |
Molecular basis for triclosan activity involves a flipping loop in the active site.
Topics: Amino Acid Sequence; Anti-Infective Agents, Local; Binding Sites; Crystallography, X-Ray; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Escherichia coli; Hydrogen Bonding; Isoleucine; Models, Molecular; Molecular Sequence Data; NAD; Oxidoreductases; Protein Conformation; Serine; Triclosan | 1999 |
Functional comparison of the NAD binding cleft of ADP-ribosylating toxins.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cholera Toxin; Diphtheria Toxin; Hydrolysis; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Phenylalanine; Poly(ADP-ribose) Polymerases; Protein Conformation; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Tyrosine | 2000 |
Effects of flavin-binding motif amino acid mutations in the NADH-cytochrome b5 reductase catalytic domain on protein stability and catalysis.
Topics: Amino Acid Motifs; Animals; Arginine; Binding Sites; Catalysis; Catalytic Domain; Circular Dichroism; Cytochrome Reductases; Cytochrome-B(5) Reductase; Enzyme Stability; Flavin-Adenine Dinucleotide; Kinetics; Models, Chemical; Mutation; NAD; Protein Binding; Protein Denaturation; Protein Structure, Tertiary; Serine; Swine; Tyrosine | 2001 |
Critical residues for the specificity of cofactors and substrates in human estrogenic 17beta-hydroxysteroid dehydrogenase 1: variants designed from the three-dimensional structure of the enzyme.
Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Binding Sites; Catalytic Domain; Cells, Cultured; Histidine; Humans; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NAD; NADP; Protein Conformation; Serine | 2001 |
Functional evaluation of serine/threonine residues in the P-Loop of Rhodobacter sphaeroides phosphoribulokinase.
Topics: Adenosine Triphosphate; Binding Sites; Electron Spin Resonance Spectroscopy; Ligands; Models, Molecular; Mutagenesis, Site-Directed; NAD; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phosphotransferases (Alcohol Group Acceptor); Rhodobacter sphaeroides; Serine; Threonine | 2001 |
Cofactor binding to Escherichia coli D-3-phosphoglycerate dehydrogenase induces multiple conformations which alter effector binding.
Topics: Allosteric Site; Carbohydrate Dehydrogenases; Catalysis; Dose-Response Relationship, Drug; Escherichia coli; Kinetics; Ligands; Mutation; NAD; Phosphoglycerate Dehydrogenase; Protein Binding; Protein Conformation; Serine; Spectrometry, Fluorescence | 2002 |
Roles of individual amino acids in helix 14 of the membrane domain of proton-translocating transhydrogenase from Escherichia coli as deduced from cysteine mutagenesis.
Topics: Alkaline Phosphatase; Amino Acids; Binding Sites; Cysteine; Escherichia coli; Ethylmaleimide; Glycine; Models, Chemical; Mutagenesis, Site-Directed; Mutation; NAD; NADP; NADP Transhydrogenases; Plasmids; Protein Structure, Tertiary; Protons; Serine | 2003 |
BIOSYNTHESIS OF SERINE IN ESCHERICHIA COLI AND SALMONELLA TYPHIMURIUM.
Topics: Alanine; Autoradiography; Carbon Isotopes; Chromatography; Escherichia coli; Glucose; Glyceric Acids; Glycerophosphates; Glycine; Ketoglutaric Acids; Metabolism; NAD; Oxidoreductases; Phosphoric Monoester Hydrolases; Pyruvates; Research; Salmonella typhimurium; Serine; Valine | 1963 |
STUDIES ON MORPHINE. IV. EFFECTS OF SOME METABOLITES ON THE "ABSTINENCE SYNDROME" TO MORPHINE ON WHITE MICE.
Topics: Alanine; Cyanides; Fluoroacetates; Glutamine; Iodoacetates; Mice; Morphine; NAD; Nalorphine; Niacin; Niacinamide; Pharmacology; Pyridines; Pyridoxine; Research; Serine; Toxicology; Tryptophan | 1963 |
THE INCORPORATION OF LABELLED CO2 INTO CELLS AND EXTRACTS OF NITROSOMONAS EUROPAEA.
Topics: Adenosine Triphosphate; Alanine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Glycine; Heptoses; Hexoses; Metabolism; NAD; Nitrosomonas; Nitrosomonas europaea; Phosphates; Pyruvates; Research; Serine; Threonine | 1964 |
PURINE METABOLISM IN THE CHICK EMBRYO: INFLUENCE OF 2-SUBSTITUTED THIADIAZOLES.
Topics: Abnormalities, Drug-Induced; Allantoin; Animals; Carbon Isotopes; Chick Embryo; Chromatography; Formates; Hypoxanthines; Insulin; Metabolism; Methionine; Methionine Sulfoximine; NAD; Niacin; Niacinamide; Nucleosides; Purines; Pyridines; Research; Serine; Sulfanilamide; Sulfanilamides; Thiadiazoles; Thiazoles; Toxicology; Triazines; Uric Acid; Uricosuric Agents | 1964 |
ORGAN AND INTRACELLULAR LOCATION OF THE METHIONINE METHYL GROUP SYNTHESIZING SYSTEM OF THE RAT.
Topics: Adenosine Triphosphate; Brain; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; Glucose; Homocysteine; Kidney; Leuconostoc; Liver; Magnesium; Methionine; Muscles; NAD; Pectoralis Muscles; Proteins; Pyridoxal Phosphate; Rats; Research; Serine; Spectrophotometry | 1964 |
PLASMA AMINO ACID PATTERNS IN ALCOHOLISM: THE EFFECTS OF ETHANOL LOADING.
Topics: Alanine; Alcoholism; Amino Acids; Autoanalysis; Biomedical Research; Blood; Ethanol; Genetics, Medical; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Methionine; NAD; NADP; Proline; Proteins; Serine; Toxicology; Valine | 1964 |
METABOLIC ACTIVITY IN COXIELLA BURNETII.
Topics: Acetates; Amino Acids; Carbohydrate Metabolism; Citric Acid Cycle; Coxiella; Coxiella burnetii; Fumarates; Glutamates; Glutamic Acid; Keto Acids; Ketoglutaric Acids; Malates; NAD; Oxaloacetates; Pyruvates; Research; Serine; Succinates | 1964 |
ENZYMATIC PROPERTIES OF ALANINE DEHYDROGENASE OF BACILLUS SUBTILIS.
Topics: Alanine; Alanine Dehydrogenase; Amino Acid Oxidoreductases; Amino Acids; Aminobutyrates; Bacillus subtilis; Benzoates; Caproates; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Cysteine; Isoleucine; Ketoglutaric Acids; Metals; NAD; Oxalates; Pyruvates; Research; Serine; Valine | 1965 |
The structure of the S127P mutant of cytochrome b5 reductase that causes methemoglobinemia shows the AMP moiety of the flavin occupying the substrate binding site.
Topics: Adenosine Monophosphate; Amino Acid Substitution; Animals; Binding Sites; Crystallography, X-Ray; Cytochrome-B(5) Reductase; Flavin-Adenine Dinucleotide; Humans; Kinetics; Methemoglobinemia; Mutagenesis, Site-Directed; NAD; Proline; Protein Conformation; Rats; Recombinant Proteins; Serine; Spectrophotometry, Ultraviolet; Substrate Specificity | 2003 |
The molecular architecture of galactose mutarotase/UDP-galactose 4-epimerase from Saccharomyces cerevisiae.
Topics: Binding Sites; Carbohydrate Epimerases; Cloning, Molecular; Crystallography, X-Ray; Cytoplasm; Electrons; Escherichia coli; Glutamine; Humans; Models, Chemical; Models, Molecular; NAD; Oxygen; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Racemases and Epimerases; Saccharomyces cerevisiae; Serine; UDPglucose 4-Epimerase | 2005 |
Evaluation of a new enzymatic method for homocysteine measurement.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Cystathionine beta-Synthase; Female; Homocysteine; Humans; Immunoenzyme Techniques; L-Lactate Dehydrogenase; Male; Middle Aged; NAD; Serine; Spectrophotometry | 2006 |
Structural basis for the alteration of coenzyme specificity in a malate dehydrogenase mutant.
Topics: Bacterial Proteins; Binding Sites; Coenzymes; Crystallization; Hydrogen Bonding; Kinetics; Malate Dehydrogenase; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; NAD; NADP; Protein Binding; Protein Structure, Tertiary; Serine; Thermus | 2006 |
Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis.
Topics: ADP-ribosyl Cyclase 1; Amino Acid Substitution; Base Sequence; Binding Sites; Catalysis; Cold Temperature; Crystallography, X-Ray; Cyclic ADP-Ribose; Dimerization; Enzyme Stability; Glutamic Acid; Guanosine Diphosphate Sugars; Humans; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Kinetics; Models, Molecular; Molecular Sequence Data; NAD; NAD+ Nucleosidase; Sequence Homology, Nucleic Acid; Serine; Static Electricity; Substrate Specificity; Water | 2006 |
Ubiquitin-mediated degradation of Rpn4 is controlled by a phosphorylation-dependent ubiquitylation signal.
Topics: Amino Acid Sequence; DNA-Binding Proteins; Molecular Sequence Data; NAD; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Signal Transduction; Transcription Factors; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination | 2007 |
Enzymatic assay of D-serine using D-serine dehydratase from Saccharomyces cerevisiae.
Topics: Alanine Racemase; Chromatography, High Pressure Liquid; Humans; Hydro-Lyases; L-Lactate Dehydrogenase; NAD; Pyruvic Acid; Saccharomyces cerevisiae; Serine; Serum Albumin, Bovine; Spectrophotometry; Stereoisomerism | 2007 |
Geographical variation in populations of Phlebotomus (Paraphlebotomus) caucasicus (Diptera: Psychodidae) in Iran.
Topics: Animals; AT Rich Sequence; Cytochromes b; Genitalia, Male; Haplotypes; Head; Insect Vectors; Iran; Male; NAD; Phlebotomus; Serine; Topography, Medical | 2007 |
Activation of ERbeta increases levels of phosphorylated nNOS and NO production through a Src/PI3K/Akt-dependent pathway in hypothalamic neurons.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor beta; Estrogens; Hypothalamus; Microtubule-Associated Proteins; Models, Biological; NAD; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Serine; Signal Transduction; src-Family Kinases; Time Factors | 2008 |
Role of the anion-binding site in catalysis and regulation of Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase.
Topics: Allosteric Site; Amino Acid Substitution; Anions; Binding, Competitive; Catalysis; Kinetics; Mycobacterium tuberculosis; NAD; Phosphoglycerate Dehydrogenase; Protein Structure, Tertiary; Serine; Substrate Specificity | 2009 |
Defective myotilin homodimerization caused by a novel mutation in MYOT exon 9 in the first Japanese limb girdle muscular dystrophy 1A patient.
Topics: Actinin; Animals; Arginine; Chlorocebus aethiops; Connectin; COS Cells; Cytoskeletal Proteins; DNA Mutational Analysis; Exons; Female; Humans; Immunoprecipitation; Japan; Lysine; Male; Microfilament Proteins; Middle Aged; Molecular Sequence Data; Muscle Proteins; Muscular Dystrophies, Limb-Girdle; Mutation, Missense; NAD; Protein Structure, Tertiary; Serine; Transfection; Two-Hybrid System Techniques | 2009 |
Cysteine as a modulator residue in the active site of xenobiotic reductase A: a structural, thermodynamic and kinetic study.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Coumarins; Cysteine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Protein Conformation; Pseudomonas putida; Serine; Substrate Specificity; Thermodynamics; Xenobiotics | 2010 |
Enzymatic synthesis of some (15)N-labelled L-amino acids.
Topics: Alanine Dehydrogenase; Amino Acids; Biocatalysis; Enzymes; Glucose 1-Dehydrogenase; Glutamate Dehydrogenase; Glutamic Acid; Isotope Labeling; Keto Acids; Leucine Dehydrogenase; Mass Spectrometry; Methionine; NAD; Nitrogen Isotopes; Serine | 2010 |
Biochemical and structural studies of uncharacterized protein PA0743 from Pseudomonas aeruginosa revealed NAD+-dependent L-serine dehydrogenase.
Topics: Bacterial Proteins; Catalysis; Crystallography, X-Ray; Mutagenesis, Site-Directed; NAD; Oxidation-Reduction; Oxidoreductases; Protein Structure, Tertiary; Pseudomonas aeruginosa; Serine; Substrate Specificity | 2012 |
¹³C magnetic resonance spectroscopy detection of changes in serine isotopomers reflects changes in mitochondrial redox status.
Topics: Animals; Carbon Isotopes; Cells, Cultured; Hepatocytes; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Serine | 2012 |
The three-dimensional structural basis of type II hyperprolinemia.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acid Substitution; Animals; Catalytic Domain; Crystallography, X-Ray; Humans; Hydrogen Bonding; Leucine; Mice; Mutation; NAD; Protein Conformation; Protein Folding; Serine | 2012 |
Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications.
Topics: Acrylamides; Adenosine Triphosphate; Animals; Carbon Isotopes; Cell Death; Cell Line, Tumor; Citric Acid Cycle; Enzyme Inhibitors; Female; Glycolysis; Humans; Isotope Labeling; Mice; Mice, SCID; NAD; Neoplasms; Nicotinamide Phosphoribosyltransferase; Pentose Phosphate Pathway; Piperidines; Serine; Xenograft Model Antitumor Assays | 2013 |
In silico model-driven cofactor engineering strategies for improving the overall NADP(H) turnover in microbial cell factories.
Topics: Bacillus subtilis; Bioreactors; Computer Simulation; Enzymes; Escherichia coli; Glycerol; NAD; NADP; Oxidation-Reduction; Pichia; Saccharomyces cerevisiae; Serine | 2015 |
l-Serine potentiates fluoroquinolone activity against Escherichia coli by enhancing endogenous reactive oxygen species production.
Topics: Anti-Bacterial Agents; Cytosol; Drug Interactions; Escherichia coli; Fluoroquinolones; Iron; NAD; Reactive Oxygen Species; Serine | 2016 |
Human serine racemase is allosterically modulated by NADH and reduced nicotinamide derivatives.
Topics: Adenosine Triphosphate; Allosteric Site; Binding Sites; Humans; Inhibitory Concentration 50; Kinetics; NAD; NADP; Niacinamide; Protein Binding; Protein Structure, Tertiary; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Serine | 2016 |
Dynamin-Related Protein 1 Promotes Mitochondrial Fission and Contributes to The Hippocampal Neuronal Cell Death Following Experimental Status Epilepticus.
Topics: Animals; Apoptosis; Caspase 3; Disease Models, Animal; Dynamins; Excitatory Amino Acid Agonists; Functional Laterality; Gene Expression Regulation; Hippocampus; Kainic Acid; Male; Mitochondrial Dynamics; NAD; Neurons; Phosphopyruvate Hydratase; Quinazolinones; Rats; Rats, Sprague-Dawley; Serine; Status Epilepticus | 2016 |
Enzymatic Activity and Thermodynamic Stability of Biliverdin IXβ Reductase Are Maintained by an Active Site Serine.
Topics: Animals; Binding Sites; Catalytic Domain; Hydrogen Bonding; Kinetics; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; NAD; Oxidoreductases Acting on CH-CH Group Donors; Protein Stability; Serine; Substrate Specificity; Thermodynamics | 2017 |
Personal model-assisted identification of NAD
Topics: Animals; Disease Models, Animal; Female; Gene Expression Regulation, Enzymologic; Genome; Glutathione; Glycine; Humans; Lipoproteins; Liver; Male; Metabolomics; Mice; Middle Aged; NAD; Non-alcoholic Fatty Liver Disease; Patient-Specific Modeling; Serine | 2017 |
In Streptomyces lividans, acetyl-CoA synthetase activity is controlled by O-serine and N
Topics: Acetate-CoA Ligase; Acetyl Coenzyme A; Acetylation; Acetyltransferases; Aminoacyltransferases; Bacterial Proteins; Cysteine Endopeptidases; DNA, Bacterial; Gene Deletion; Group III Histone Deacetylases; Lysine; NAD; Serine; Streptomyces lividans | 2018 |
Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation.
Topics: Cell Line, Tumor; Cell Nucleus; Citric Acid Cycle; DNA Methylation; DNA, Mitochondrial; Epigenesis, Genetic; Folic Acid; HEK293 Cells; Humans; Methionine; Mitochondria; NAD; Osteoblasts; Oxidation-Reduction; Serine; Tricarboxylic Acids | 2018 |
NAD(P)HX repair deficiency causes central metabolic perturbations in yeast and human cells.
Topics: Cells, Cultured; Humans; Metabolic Diseases; Metabolome; NAD; NADP; Racemases and Epimerases; Saccharomyces cerevisiae; Serine | 2018 |
The NAD
Topics: Breast Neoplasms; Cell Line, Tumor; Cytokines; Female; Humans; MCF-7 Cells; NAD; Nicotinamide Phosphoribosyltransferase; Phosphoglycerate Dehydrogenase; Serine; Signal Transduction | 2018 |
c-Jun N-terminal kinase (JNK)-mediated phosphorylation of SARM1 regulates NAD
Topics: Adenosine Triphosphate; Armadillo Domain Proteins; Cell Line, Tumor; Cell Respiration; Cytoskeletal Proteins; HEK293 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Mitochondria; NAD; NAD+ Nucleosidase; Oxidative Stress; Phosphorylation; Serine | 2018 |
3-Phosphoglycerate Transhydrogenation Instead of Dehydrogenation Alleviates the Redox State Dependency of Yeast de Novo l-Serine Synthesis.
Topics: Feedback, Physiological; Glyceric Acids; Humans; Hydrogenation; NAD; Oxidation-Reduction; Phosphoglycerate Dehydrogenase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine | 2019 |
Serine Catabolism Feeds NADH when Respiration Is Impaired.
Topics: Animals; Cell Hypoxia; Cell Line; Humans; Mice; Mice, Inbred C57BL; Mice, Nude; Mitochondria; NAD; Oxygen; Serine | 2020 |
Fluorescent Probes for Monitoring Serine Ubiquitination.
Topics: Adenosine Diphosphate; Amino Acid Motifs; Bacterial Proteins; Biochemistry; Fluorescent Dyes; Legionella pneumophila; NAD; Serine; Ubiquitination | 2020 |
NADH Ties One-Carbon Metabolism to Cellular Respiration.
Topics: Carbon; Cell Respiration; NAD; Respiration; Serine | 2020 |
The heterocyclic compound Tempol inhibits the growth of cancer cells by interfering with glutamine metabolism.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cyclic N-Oxides; Female; Glutamine; Glycolysis; Heterocyclic Compounds; Humans; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Molecular Docking Simulation; NAD; Neoplasms; Oxidative Phosphorylation; Pyruvic Acid; Reactive Oxygen Species; Serine; Spin Labels; Xenograft Model Antitumor Assays | 2020 |
Role of a cysteine residue in substrate entry and catalysis in MtHIBADH: Analysis by chemical modifications and site-directed mutagenesis.
Topics: Alanine; Alcohol Oxidoreductases; Bacterial Proteins; Catalysis; Cysteine; Dinitrobenzenes; Hydrogen Bonding; Models, Molecular; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; NAD; p-Chloromercuribenzoic Acid; Protein Conformation; Recombinant Proteins; Serine; Structure-Activity Relationship; Substrate Specificity | 2021 |
Alteration of cofactor specificity of the acrylyl-CoA reductase from Escherichia coli.
Topics: Amino Acid Substitution; Arginine; Aspartic Acid; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Mutagenesis, Site-Directed; NAD; NADP; Protein Engineering; Quinone Reductases; Serine; Substrate Specificity | 2021 |
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitors Necrostatin-1 (Nec-1) and 7-Cl-O-Nec-1 (Nec-1s) are potent inhibitors of NAD(P)H: Quinone oxidoreductase 1 (NQO1).
Topics: Apoptosis; Humans; Imidazoles; Indoles; NAD; NAD(P)H Dehydrogenase (Quinone); Quinones; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; Threonine | 2021 |
O-GlcNAcylation and stablization of SIRT7 promote pancreatic cancer progression by blocking the SIRT7-REGγ interaction.
Topics: Autoantigens; Carcinoma, Pancreatic Ductal; Cell Proliferation; Humans; N-Acetylglucosaminyltransferases; NAD; Pancreatic Neoplasms; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Serine; Sirtuins | 2022 |
Loss of peroxisomal NAD kinase 3 (NADK3) affects photorespiration metabolism in Arabidopsis.
Topics: Arabidopsis; Carbon Dioxide; Glycine; NAD; NADP; Serine | 2023 |
Metabolic alterations unravel the maternofetal immune responses with disease severity in pregnant women infected with SARS-CoV-2.
Topics: COVID-19; Cytokines; Female; Glycine; Humans; Immunity; Infant, Newborn; Interferon-alpha; Interleukin-6; Interleukin-9; Lactates; NAD; Patient Acuity; Pregnancy; Pregnant Women; Pyruvates; Riboflavin; SARS-CoV-2; Serine; Threonine | 2023 |