serine and morphine

Topics: Animals; Brain; Calcium; Choline; Ethanolamines; Male; Microsomes; Morphine; Phospholipids; Rats; Serine; Time Factors

Topics: Adenylyl Cyclases; Analgesia; Animals; Brain; Cyclic AMP; Dihydroxyphenylalanine; Drug Interactions; Drug Tolerance; Male; Mice; Mice, Inbred ICR; Morphine; Pargyline; Serine; Theophylline; Time Factors; Tryptophan

Topics: Animals; Apomorphine; Brain Chemistry; Catalepsy; Catechols; Caudate Nucleus; Chlorpromazine; Clonidine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Fluorometry; Homovanillic Acid; Humans; Male; Methyltyrosines; Mice; Morphine; Motor Activity; Rats; Serine; Species Specificity; Stereotaxic Techniques; Thiocarbamates

Topics: Amantadine; Analgesia; Animals; Apomorphine; Dibenzothiazepines; Dopamine; Drug Synergism; Drug Tolerance; Male; Mice; Mice, Inbred Strains; Morphine; Perphenazine; Phenoxybenzamine; Receptors, Adrenergic; Serine; Spiro Compounds

Topics: Analgesia; Animals; Benzofurans; Male; Morphine; Pyrrolidines; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serine

Topics: Adenylyl Cyclases; Animals; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Activation; Etorphine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Morphine; Mutagenesis, Site-Directed; Receptors, Opioid, mu; Serine; Signal Transduction; Threonine

Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Analgesics, Opioid; Animals; Binding Sites; Brain; CHO Cells; Cricetinae; Enzyme Inhibitors; GRB2 Adaptor Protein; Insulin; Insulin Receptor Substrate Proteins; Male; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Morphine; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Receptors, Opioid, mu; Serine; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1

Topics: Alanine; Cyanides; Fluoroacetates; Glutamine; Iodoacetates; Mice; Morphine; NAD; Nalorphine; Niacin; Niacinamide; Pharmacology; Pyridines; Pyridoxine; Research; Serine; Toxicology; Tryptophan

Topics: Animals; Cognition Disorders; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Maze Learning; Morphine; Morphine Dependence; Neuronal Plasticity; Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission

Topics: Analgesics, Opioid; Animals; Blotting, Western; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation; Hippocampus; Immunoblotting; Isoelectric Focusing; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Morphine; Mutation; Nerve Tissue Proteins; Neurons; PC12 Cells; Phosphorylation; Protein Kinase C; Rats; RNA Processing, Post-Transcriptional; Serine; Synaptosomal-Associated Protein 25; Synaptosomes; Time Factors; Transfection

Topics: 14-3-3 Proteins; Amino Acid Sequence; Animals; Cell Membrane; GTP Phosphohydrolases; Kinetics; Male; Mice; Mice, Knockout; Molecular Sequence Data; Morphine; Periaqueductal Gray; Phosphoserine; Protein Subunits; Receptors, Opioid, mu; RGS Proteins; Serine; Signal Transduction

Topics: Animals; Area Under Curve; Blotting, Western; Brain; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Narcotics; Nuclear Proteins; Okadaic Acid; Pain; Phosphoprotein Phosphatases; Phosphorylation; Serine; Threonine; Time Factors

Topics: Amino Acid Substitution; Animals; CHO Cells; Cricetinae; Cricetulus; Humans; Morphine; Mutation; Oligopeptides; Phosphorylation; Receptors, Opioid, delta; Serine

Topics: Analgesics; Animals; Drug Synergism; Male; Morphine; Naloxone; Pain Measurement; Quinolones; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Serine; Spinal Cord; Stereoisomerism

Topics: Animals; Blotting, Western; Gene Expression; Hypothalamus; Immunohistochemistry; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morphine; Paraventricular Hypothalamic Nucleus; Phosphorylation; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Serine; Solitary Nucleus; Tyrosine 3-Monooxygenase

Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Endocytosis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Activation; G-Protein-Coupled Receptor Kinases; Gene Silencing; Hot Temperature; Injections, Intraventricular; Male; Mice; Molecular Sequence Data; Morphine; Neurons; Oligonucleotides, Antisense; Pain; Pain Measurement; Pain Threshold; Periaqueductal Gray; Phosphorylation; Receptors, Opioid, mu; RGS Proteins; Serine; Synaptosomes; Time Factors

Topics: Analgesics, Opioid; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Carrier Proteins; Drug Tolerance; Electrophoresis, Gel, Two-Dimensional; G-Protein-Coupled Receptor Kinase 2; Glycosylation; Immunoglobulin G; Injections, Intraventricular; Male; Mice; Molecular Chaperones; Morphine; Nerve Tissue Proteins; Pain Measurement; Phosphorylation; Reaction Time; Receptors, Opioid, mu; Serine; Signal Transduction; Synaptosomes

Topics: Animals; Dependovirus; Drug Tolerance; Gene Expression Regulation; Gene Transfer Techniques; Genes, Reporter; Male; Mice; Morphine; Mutation; Naloxone; Pain; Pain Measurement; Receptors, Opioid, mu; Serine; Spinal Cord; Time Factors

Topics: Analgesics; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; Hypnotics and Sedatives; Injections, Intraventricular; Male; Midazolam; Morphine; Pain Measurement; Rats; Rats, Wistar; Serine; Spinal Cord

Topics: Aminoacetonitrile; Animals; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Drug Implants; Isoquinolines; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morphine; Morphine Dependence; Myocardium; Naloxone; Naphthalenes; Narcotic Antagonists; Norepinephrine; Phosphorylation; Protein Kinase C-delta; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Serine; Substance Withdrawal Syndrome; Sulfonamides; Tyrosine 3-Monooxygenase

Topics: Analgesics, Opioid; Animals; Brain; D-Amino-Acid Oxidase; Gene Expression Regulation, Enzymologic; Male; Morphine; Racemases and Epimerases; Rats; Rats, Wistar; RNA, Messenger; Serine; Time

Topics: Adenylyl Cyclases; Analgesics, Opioid; Animals; Arrestins; beta-Arrestins; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Flow Cytometry; G-Protein-Coupled Receptor Kinase 2; Guanosine 5'-O-(3-Thiotriphosphate); Mitogen-Activated Protein Kinase 3; Morphine; Oligopeptides; Protein Binding; Protein Transport; Receptors, Opioid, delta; Serine; Signal Transduction; src-Family Kinases; Tetrahydroisoquinolines; Transfection

Topics: Analgesics, Opioid; Arrestins; Benzamides; beta-Arrestin 2; beta-Arrestins; Cell Line, Transformed; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Green Fluorescent Proteins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Morphine; Oligopeptides; Pertussis Toxin; Phosphorylation; Piperazines; Protein Binding; Protein Transport; Quinolines; Receptors, Opioid, delta; Serine; Sulfur Isotopes; Transfection

Topics: Analgesics; Animals; Dextromethorphan; Drug Interactions; Drug Therapy, Combination; Hyperalgesia; Magnesium Sulfate; Male; Mice; Morphine; Pain Measurement; Receptors, N-Methyl-D-Aspartate; Serine

Topics: Alanine; Analgesics, Opioid; Animals; Drug Tolerance; Gene Knock-In Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Morphine; Pain Measurement; Phosphorylation; Receptors, Opioid, mu; Serine

Topics: Alanine; Analysis of Variance; Animals; Behavior, Animal; Carrier Proteins; Cell Cycle Proteins; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Gene Transfer Techniques; Green Fluorescent Proteins; Guanylate Kinases; Hippocampus; In Situ Nick-End Labeling; Long-Term Potentiation; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Motor Activity; Mutation; Narcotics; Nuclear Proteins; Phosphorylation; Protein Transport; Random Allocation; Receptors, AMPA; Serine; Subcellular Fractions

Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Analgesics, Opioid; Animals; Blotting, Western; Cell Line, Tumor; Cyclic AMP; Enzyme Activation; GTP-Binding Protein alpha Subunits, Gs; Immunoprecipitation; Isoproterenol; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morphine; Mutation; Phosphorylation; Protein Binding; Receptors, Adrenergic, beta-2; Receptors, Opioid, mu; Serine; Threonine; Transfection

Topics: Animals; Corticosterone; Dopamine; Male; Morphine; Morphine Dependence; Naloxone; Neurons; Norepinephrine; Nucleus Accumbens; Phosphorylation; Proto-Oncogene Proteins c-fos; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Serine; Substance Withdrawal Syndrome; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

Topics: Animals; Brain; Conditioning, Operant; Disease Models, Animal; Drug-Seeking Behavior; Gene Expression Regulation; Male; Morphine; Narcotics; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Self Administration; Serine; Time Factors

Topics: Analgesics, Opioid; Animals; Calcineurin; Cyclic AMP-Dependent Protein Kinases; Dizocilpine Maleate; Drug-Seeking Behavior; Excitatory Amino Acid Antagonists; Feeding Behavior; Male; Morphine; Nucleus Accumbens; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reward; Serine; Substance Withdrawal Syndrome

Topics: Analgesia; Animals; D-Amino-Acid Oxidase; Drug Tolerance; Male; Microinjections; Morphine; Oligodeoxyribonucleotides; Pain Threshold; Periaqueductal Gray; Racemases and Epimerases; Rats, Sprague-Dawley; Receptors, Purinergic P2X7; Serine; Up-Regulation

Topics: Analgesics, Opioid; Animals; Astrocytes; Calcium Signaling; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cytoplasmic Vesicles; Excitatory Postsynaptic Potentials; GABAergic Neurons; Male; Morphine; Nucleus Accumbens; Phosphoproteins; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Serine

Topics: ABO Blood-Group System; Acetylgalactosamine; Acetylglucosamine; Amino Acids; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Fucose; Galactose; Glucosamine; Glycoproteins; Hemagglutination Inhibition Tests; Humans; Infant, Newborn; Lewis Blood Group Antigens; Meconium; Precipitins; Serine; Threonine