Compounds > serine

serine and malonic acid

serine has been researched along with malonic acid in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cígler, P; Hoffman, HE; Jirásková, J; Konvalinka, J; Sanda, M; Schraml, J1
Ha, NC; Kim, SY; Kim, YS; Koo, HM; Lee, HS; Lee, TH; Oh, BH; Shin, S1
Barker, J; Cesura, A; Ebneth, A; Felicetti, B; Mack, V; Mather, O; Moraes, I; Schonfeld, D; Smith, MA; Wood, M1
Major, DT; Nitoker, N1

Other Studies

4 other study(ies) available for serine and malonic acid

ArticleYear
Hydroxamic acids as a novel family of serine racemase inhibitors: mechanistic analysis reveals different modes of interaction with the pyridoxal-5'-phosphate cofactor.
    Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19

    Topics: Animals; Asparagine; Binding, Competitive; Enzyme Inhibitors; Hydroxamic Acids; Mice; Oximes; Pyridoxal Phosphate; Racemases and Epimerases; Structure-Activity Relationship

2009
Structure of malonamidase E2 reveals a novel Ser-cisSer-Lys catalytic triad in a new serine hydrolase fold that is prevalent in nature.
    The EMBO journal, 2002, Jun-03, Volume: 21, Issue:11

    Topics: Amidohydrolases; Amino Acid Sequence; Bacterial Proteins; Bradyrhizobium; Catalytic Domain; Crystallography, X-Ray; Escherichia coli; Ions; Lysine; Malonates; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Folding; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Serine; Substrate Specificity

2002
The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding.
    The Journal of biological chemistry, 2010, Apr-23, Volume: 285, Issue:17

    Topics: Animals; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Malonates; Protein Binding; Protein Multimerization; Protein Structure, Quaternary; Protein Structure, Tertiary; Pyridoxal Phosphate; Racemases and Epimerases; Rats; Receptors, N-Methyl-D-Aspartate; Serine

2010
Understanding the reaction mechanism and intermediate stabilization in mammalian serine racemase using multiscale quantum-classical simulations.
    Biochemistry, 2015, Jan-20, Volume: 54, Issue:2

    Topics: Alanine Racemase; Animals; Catalytic Domain; Humans; Malonates; Molecular Dynamics Simulation; Pyridoxal Phosphate; Racemases and Epimerases; Rats; Serine; Thermodynamics

2015