serine has been researched along with kainic acid in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.26) | 18.7374 |
| 1990's | 14 (29.79) | 18.2507 |
| 2000's | 20 (42.55) | 29.6817 |
| 2010's | 9 (19.15) | 24.3611 |
| 2020's | 2 (4.26) | 2.80 |
| Authors | Studies |
|---|---|
| Jankásková, B; Lisý, V; Stastný, F | 1 |
| Li, M; Ryan, R; Wood, PL | 1 |
| Berg, M; Bruhn, T; Cobo, M; Diemer, NH | 1 |
| Astier, H; Tapia-Arancibia, L | 1 |
| Salt, TE | 1 |
| Jankásková, B; Lisý, V; Murphy, S; Pearce, B; Stastný, F | 1 |
| Bian, ZC; Oswald, RE; Wo, ZG | 1 |
| Bowlby, MR | 1 |
| Lehmann, JC; Procureur, D; Wood, PL | 1 |
| Bowie, D; Mayer, ML; Partin, KM | 1 |
| Molliver, ME; Schell, MJ; Snyder, SH | 1 |
| Jhamandas, JH; Zidichouski, JA | 1 |
| Hampson, DR; Huang, XP; MacDonald, JF; Taverna, FA; Wang, LY | 1 |
| Chung, HJ; Kavanaugh, MP; Pratt, K; Rosenberg, PA; Schnuer, J; Wang, GJ; Zable, AC | 1 |
| Amara, SG; Johnston, GA; Mitrovic, AD; Vandenberg, RJ | 1 |
| Kanner, BI; Zhang, Y | 1 |
| Baudry, M; Crispino, M; Feldman, JD; Herschman, HR; Hoe, W; Vician, L | 1 |
| Hashimoto, A; Kanda, J; Oka, T | 1 |
| Kimmich, GA; Manglapus, M; Randles, J; Roussie, J | 1 |
| Sadzuka, Y; Sonobe, T; Yamashita, Y | 1 |
| Belluardo, N; Korhonen, L; Lindholm, D; Mudo, G | 1 |
| Allis, CD; Borrelli, E; Crosio, C; Heitz, E; Sassone-Corsi, P | 1 |
| Apricò, K; Beart, PM; Crawford, D; O'Shea, RD | 1 |
| Behl, C; Conrad, S; Goodenough, S; Skutella, T | 1 |
| Behrens, A; Brecht, S; Chromik, A; Claussen, M; Davis, RJ; Flavell, RA; Goetz, M; Herdegen, T; Kirchhof, R; Kuan, CY; Nicolaus, T; Pearse, D; Raivich, G; Vaudano, E; Waetzig, V; Wagner, E; Wessig, J; Willesen, M | 1 |
| Behl, C; Goodenough, S; Pietrzik, C; Schleusner, D; Skutella, T | 1 |
| Hayakawa, M; Ingi, T; Inuzuka, M | 1 |
| Coulson, JM; Mori, N; Morii, H; Nakano, I; Yamada, T | 1 |
| Balan, L; Dumin, E; Kartvelishvily, E; Shleper, M; Wolosker, H | 1 |
| Bowser, MT; O'Brien, KB | 1 |
| Inokuchi, K; Kataoka, M; Kuwahara, R; Matsuo, R; Sekiguchi, M; Takahashi, M | 1 |
| Hassel, B; Henjum, S | 1 |
| Bai, D; Gong, XQ; Zabek, RL | 1 |
| Fumagalli, E; Funicello, M; Gobbi, M; Mennini, T; Rauen, T | 1 |
| Bozzi, Y; Chikhladze, M; Condliffe, S; Franceschetti, S; Grumelli, C; Matteoli, M; Pozzi, D; Proux-Gillardeaux, V; Takahashi, M; Verderio, C | 1 |
| Cho, SS; Choi, DH; Chung, CK; Jeon, GS; Kim, DW; Lee, HN | 1 |
| Cho, GJ; Choi, MY; Choi, WS; Jeon, BT; Kang, SS; Kim, HJ; Kim, YH; Kim, YS; Lee, DH; Roh, GS | 1 |
| Chintala, SK; Mali, RS; Zhang, XM | 1 |
| Chamberlain, S; Henley, JM; Jaafari, N; Kantamneni, S; Konopacki, FA; Mellor, JR; Rocca, DL; Rubin, P; Wilkinson, KA | 1 |
| Baldridge, WH; Daniels, BA; Tremblay, F; Wood, L | 1 |
| Bozzi, Y; Dunleavy, M; Henshall, DC; Provenzano, G | 1 |
| Fitzgerald, EF; Huganir, RL; Hunganir, RL; Jensen, FE; Klein, PM; Rakhade, SN; Sun, H; Zhou, C | 1 |
| Chu, D; Gong, CX; Iqbal, K; Jin, N; Liu, F; Tan, J; Xie, S; Yin, X | 1 |
| Chan, SH; Chen, SD; Chuang, YC; Huang, CW; Lin, JW; Lin, TK; Liou, CW; Zhen, YY | 1 |
| Adula, KP; Casaccia, P; Huntley, GW; Kezunovic, N; Vidaurre, OG; Wentling, M; Zhu, Y | 1 |
| Kim, JE; Lee, DS | 1 |
| Kang, TC; Kim, JE; Kim, MJ; Kim, TH; Lee, DS; Park, H | 1 |
47 other study(ies) available for serine and kainic acid
| Article | Year |
|---|---|
Effect of gamma-glutamyl transpeptidase inhibitors on the transport of glutamate into neuronal and glial primary cultures.
Topics: Aging; Animals; Biological Transport; Borates; Brain; Cells, Cultured; Chickens; Diazooxonorleucine; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Kainic Acid; Neuroglia; Neurons; Serine | 1992 |
NMDA-, but not kainate- or quisqualate-dependent increases in cerebellar cGMP are dependent upon monoaminergic innervation.
Topics: Animals; Cerebellum; Cyclic GMP; Kainic Acid; Male; Mice; N-Methylaspartate; Neurotransmitter Agents; Norepinephrine; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Serine | 1992 |
Limbic seizure-induced changes in extracellular amino acid levels in the hippocampal formation: a microdialysis study of freely moving rats.
Topics: Amino Acids; Amygdala; Animals; Aspartic Acid; Brain Mapping; Chromatography, High Pressure Liquid; Dialysis; Extracellular Space; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kainic Acid; Limbic System; Male; Rats; Rats, Wistar; Seizures; Serine; Synaptic Transmission | 1992 |
Pharmacological properties of the NMDA receptor involved in somatostatin release from cortical neurons.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Female; Glutamates; Kainic Acid; Kynurenic Acid; Neurons; Pregnancy; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Somatostatin; Zinc | 1990 |
Modulation of NMDA receptor-mediated responses by glycine and D-serine in the rat thalamus in vivo.
Topics: Action Potentials; Animals; Aspartic Acid; Glycine; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine; Strychnine; Thalamus | 1989 |
Effect of inhibitors of gamma-glutamyl transpeptidase on the uptake of glutamate and aspartate into cultured astroglial cells from the glycogen body and cerebral hemispheres of the embryonic chick.
Topics: Animals; Aspartic Acid; Astrocytes; Biological Transport; Borates; Brain; Cells, Cultured; Chick Embryo; Diazooxonorleucine; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Kainic Acid; Serine; Spinal Cord | 1988 |
Asn-265 of frog kainate binding protein is a functional glycosylation site: implications for the transmembrane topology of glutamate receptors.
Topics: Amino Acid Sequence; Animals; Asparagine; Base Sequence; Cell Line; Cell Membrane; Glycosylation; Hexosaminidases; Humans; Kainic Acid; Microsomes; Molecular Sequence Data; Mutation; Ranidae; Receptors, Kainic Acid; Recombinant Proteins; Serine | 1995 |
Pregnenolone sulfate potentiation of N-methyl-D-aspartate receptor channels in hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Electrophysiology; Glycine; Hippocampus; Ibotenic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Neurons; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine | 1993 |
7-Chlorokynurenate prevents NMDA-induced and kainate-induced striatal lesions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Diseases; Choline O-Acetyltransferase; Corpus Striatum; Dose-Response Relationship, Drug; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine | 1993 |
Structural determinants of allosteric regulation in alternatively spliced AMPA receptors.
Topics: Allosteric Regulation; Alternative Splicing; Amino Acid Sequence; Animals; Benzothiadiazines; Embryo, Mammalian; Embryo, Nonmammalian; Glutamic Acid; Glutamine; Humans; Kainic Acid; Kidney; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Point Mutation; Receptors, AMPA; Receptors, Kainic Acid; Serine; Transfection; Xenopus laevis | 1995 |
D-serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release.
Topics: Animals; Antibody Specificity; Astrocytes; Autoradiography; Brain; Cells, Cultured; D-Amino-Acid Oxidase; Glutamic Acid; Hippocampus; Immunohistochemistry; Kainic Acid; Models, Neurological; Organ Specificity; Rats; Serine; Stereoisomerism; Synapses; Telencephalon; Tritium | 1995 |
Electrophysiological characterization of excitatory amino acid responses in rat lateral parabrachial neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Evoked Potentials; In Vitro Techniques; Kainic Acid; Kinetics; Magnesium; Male; N-Methylaspartate; Neurons; Pons; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Serine; Time Factors | 1993 |
Phosphorylation and modulation of a kainate receptor (GluR6) by cAMP-dependent protein kinase.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Brain; Cells, Cultured; Concanavalin A; Evoked Potentials; Humans; Kainic Acid; Kidney; Kinetics; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Protein Kinases; Receptors, Glutamate; Receptors, Kainic Acid; Serine; Wheat Germ Agglutinins | 1993 |
High affinity glutamate transport in rat cortical neurons in culture.
Topics: 2-Aminoadipic Acid; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Biological Transport; Cells, Cultured; Cerebral Cortex; Immunoblotting; Immunohistochemistry; Kainic Acid; Kinetics; Neurons; Oocytes; Rats; Rats, Sprague-Dawley; Serine; Synaptosomes | 1998 |
Identification of functional domains of the human glutamate transporters EAAT1 and EAAT2.
Topics: Amino Acid Sequence; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 2; Gene Expression; Glutamates; Glutamic Acid; Humans; Kainic Acid; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Receptors, Neurotransmitter; Recombinant Fusion Proteins; Recombinant Proteins; Sequence Alignment; Serine; Xenopus laevis | 1998 |
Two serine residues of the glutamate transporter GLT-1 are crucial for coupling the fluxes of sodium and the neurotransmitter.
Topics: Amino Acid Substitution; Amino Acid Transport System X-AG; Aspartic Acid; ATP-Binding Cassette Transporters; Binding Sites; Biological Transport; Glutamic Acid; Glycine; HeLa Cells; Humans; Kainic Acid; Kinetics; Mutagenesis, Site-Directed; Neurotransmitter Agents; Recombinant Proteins; Serine; Sodium | 1999 |
The salt-inducible kinase, SIK, is induced by depolarization in brain.
Topics: Animals; Blotting, Northern; Cerebral Cortex; Colforsin; Cycloheximide; Epilepsy; Excitatory Amino Acid Agonists; Gene Expression Regulation, Enzymologic; Genes, Immediate-Early; Hippocampus; Kainic Acid; Membrane Potentials; Molecular Sequence Data; Neurons; PC12 Cells; Phylogeny; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Rats; RNA, Messenger; Salts; Seizures; Sequence Homology, Amino Acid; Serine; src-Family Kinases | 2000 |
Effects of N-methyl-D-aspartate, kainate or veratridine on extracellular concentrations of free D-serine and L-glutamate in rat striatum: an in vivo microdialysis study.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Kainic Acid; Male; Microdialysis; N-Methylaspartate; Perfusion; Rats; Rats, Wistar; Serine; Time Factors; Veratridine | 2000 |
Characterization of Na+-coupled glutamate/aspartate transport by a rat brain astrocyte line expressing GLAST and EAAC1.
Topics: Alanine; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Blotting, Western; Carrier Proteins; Cell Line; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 3; Ganglionic Stimulants; Genistein; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Ionophores; Kainic Acid; Protein Isoforms; Protein-Tyrosine Kinases; Quaternary Ammonium Compounds; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Sodium; Symporters; Telencephalon; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Effects of glutamate transporter inhibitors on the antitumor activity of doxorubicin.
Topics: Amino Acid Transport System X-AG; Animals; Antineoplastic Agents; Doxorubicin; Female; Glutamates; Humans; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Reverse Transcriptase Polymerase Chain Reaction; Serine; Tumor Cells, Cultured | 2002 |
Increase in Bcl-2 phosphorylation and reduced levels of BH3-only Bcl-2 family proteins in kainic acid-mediated neuronal death in the rat brain.
Topics: Animals; bcl-2-Associated X Protein; Blotting, Western; Brain; Butylated Hydroxytoluene; Cell Count; Cell Death; Cells, Cultured; Embryo, Mammalian; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Immunohistochemistry; In Situ Nick-End Labeling; Kainic Acid; Male; Neurons; Nuclear Proteins; Phosphorylation; Precipitin Tests; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Serine; Staining and Labeling; Time Factors | 2003 |
Chromatin remodeling and neuronal response: multiple signaling pathways induce specific histone H3 modifications and early gene expression in hippocampal neurons.
Topics: Amino Acid Sequence; Animals; Benzazepines; Chromatin; Chromatin Assembly and Disassembly; Dopamine Agonists; Gene Expression; Genes, fos; Hippocampus; Histones; In Situ Hybridization; Kainic Acid; MAP Kinase Signaling System; Mice; Molecular Sequence Data; Muscarinic Agonists; Neurons; Phosphorylation; Pilocarpine; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Serine; Signal Transduction | 2003 |
Binding and transport of [3H](2S,4R)- 4-methylglutamate, a new ligand for glutamate transporters, demonstrate labeling of EAAT1 in cultured murine astrocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Transport System X-AG; Amino Acids, Dicarboxylic; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Binding, Competitive; Blotting, Western; Cell Membrane; Cells, Cultured; D-Aspartic Acid; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Glutamates; Kainic Acid; Ligands; Mice; Potassium; Serine; Sodium; Temperature; Tritium | 2004 |
Inactivation of glycogen synthase kinase-3beta protects against kainic acid-induced neurotoxicity in vivo.
Topics: Animals; Behavior, Animal; Blotting, Western; Butadienes; Cell Death; Cell Survival; Cerebellum; Enzyme Activation; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunohistochemistry; Kainic Acid; Lithium Chloride; Male; Mice; Mitogen-Activated Protein Kinase 1; Neurotoxicity Syndromes; Nitriles; Organ Culture Techniques; Phosphorylation; Serine; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine | 2004 |
Specific pathophysiological functions of JNK isoforms in the brain.
Topics: Animals; Autonomic Denervation; Behavior, Animal; Blotting, Western; Brain; Brain Injuries; Cell Count; Cell Death; Enzyme Activation; Facial Nerve Diseases; Female; Functional Laterality; Gene Expression Regulation; Immunohistochemistry; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Isoenzymes; Kainic Acid; Male; Medial Forebrain Bundle; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neurons; Oxidopamine; Phosphorylation; Proto-Oncogene Proteins c-jun; Serine; Staining and Labeling; Time Factors; Tyrosine 3-Monooxygenase | 2005 |
Glycogen synthase kinase 3beta links neuroprotection by 17beta-estradiol to key Alzheimer processes.
Topics: Animals; Animals, Newborn; Antibodies, Monoclonal; Blotting, Western; Cell Count; Cell Death; Cells, Cultured; Drug Interactions; Embryo, Mammalian; Estradiol; Excitatory Amino Acid Agonists; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Phosphorylation; Pregnancy; Propidium; Rats; Rats, Sprague-Dawley; Serine; tau Proteins; Tetrazolium Salts; Thiazoles; Tyrosine | 2005 |
Serinc, an activity-regulated protein family, incorporates serine into membrane lipid synthesis.
Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Animals; Blotting, Western; Brain; Cell Membrane; Chlorocebus aethiops; Chromatography, Thin Layer; COS Cells; DNA, Complementary; Down-Regulation; Endoplasmic Reticulum; Escherichia coli; Hippocampus; In Situ Hybridization; Kainic Acid; Lipids; Male; Microsomes; Models, Biological; Molecular Sequence Data; Multigene Family; Neurons; Phosphatidylserines; Protein Binding; Protein Structure, Tertiary; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Sphingolipids; Two-Hybrid System Techniques; Up-Regulation | 2005 |
Site-specific phosphorylation of SCG10 in neuronal plasticity: role of Ser73 phosphorylation by N-methyl D-aspartic acid receptor activation in rat hippocampus.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Hippocampus; Kainic Acid; Male; Membrane Proteins; Microtubule Proteins; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Nerve Growth Factors; Neurons; Pentylenetetrazole; Peptide Fragments; Phosphorylation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Serine; Time Factors | 2006 |
Neuron-derived D-serine release provides a novel means to activate N-methyl-D-aspartate receptors.
Topics: Animals; Astrocytes; Brain; Cells, Cultured; Cytosol; Kainic Acid; Neurons; Propionates; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synapses | 2006 |
Measuring D-serine efflux from mouse cortical brain slices using online microdialysis-capillary electrophoresis.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Electrophoresis, Capillary; In Vitro Techniques; Kainic Acid; Kinetics; Male; Mice; Mice, Inbred C57BL; Microdialysis; Online Systems; Perfusion; Potassium; Receptors, AMPA; Receptors, Kainic Acid; Serine; Stereoisomerism | 2006 |
Development- and activity-dependent regulation of SNAP-25 phosphorylation in rat brain.
Topics: Animals; Animals, Newborn; Brain; Cells, Cultured; Female; Hippocampus; Kainic Acid; Male; Neurons; Phosphorylation; Rats; Rats, Wistar; Seizures; Serine; Synaptosomal-Associated Protein 25 | 2006 |
High-affinity glycine and glutamate transport in pig forebrain white and gray matter: a quantitative study.
Topics: Animals; Biological Transport; Excitatory Amino Acid Transporter 2; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Glutathione; Glycine; Glycine Hydroxymethyltransferase; Glycine Plasma Membrane Transport Proteins; Kainic Acid; Prosencephalon; Sarcosine; Serine; Swine | 2007 |
D-Serine inhibits AMPA receptor-mediated current in rat hippocampal neurons.
Topics: Action Potentials; Amino Acids; Aminobutyrates; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kainic Acid; Molecular Structure; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism; Valine | 2007 |
Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1.
Topics: Amino Acid Transport System X-AG; Animals; Cell Line; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamic Acid; Humans; Kainic Acid; Kinetics; Male; Neuroprotective Agents; Rats; Riluzole; Serine; Synaptosomes; Transfection | 2008 |
Activity-dependent phosphorylation of Ser187 is required for SNAP-25-negative modulation of neuronal voltage-gated calcium channels.
Topics: Animals; Calcium Channels; Electrophysiology; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Models, Genetic; Mutation; Neurons; Phosphorylation; Serine; Synaptosomal-Associated Protein 25; Vesicle-Associated Membrane Protein 2 | 2008 |
Expression of L-serine biosynthetic enzyme 3-phosphoglycerate dehydrogenase (Phgdh) and neutral amino acid transporter ASCT1 following an excitotoxic lesion in the mouse hippocampus.
Topics: Amino Acid Transport System ASC; Animals; Hippocampus; Immunohistochemistry; Kainic Acid; Mice; Mice, Inbred ICR; Nerve Degeneration; Neuroglia; Neurons; Phosphoglycerate Dehydrogenase; Serine; Stereoisomerism; Up-Regulation | 2009 |
Protein kinase Cdelta is associated with 14-3-3 phosphorylation in seizure-induced neuronal death.
Topics: 14-3-3 Proteins; Animals; bcl-Associated Death Protein; Caspase 3; Cell Death; Disease Models, Animal; Excitatory Amino Acid Agonists; Gene Expression Regulation; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred ICR; Neurons; Phosphopyruvate Hydratase; Phosphorylation; Protein Kinase C-delta; Seizures; Serine | 2010 |
A decrease in phosphorylation of cAMP-response element-binding protein (CREBP) promotes retinal degeneration.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amacrine Cells; Animals; Apoptosis; Blotting, Western; CREB-Binding Protein; Electrophoretic Mobility Shift Assay; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Immunohistochemistry; In Situ Nick-End Labeling; Intravitreal Injections; Kainic Acid; Mice; Phosphorylation; Retina; Retinal Degeneration; Retinal Ganglion Cells; Serine | 2011 |
Agonist-induced PKC phosphorylation regulates GluK2 SUMOylation and kainate receptor endocytosis.
Topics: Alanine; Amino Acid Substitution; Animals; Blotting, Western; Cells, Cultured; Chlorocebus aethiops; COS Cells; Endocytosis; GluK2 Kainate Receptor; HEK293 Cells; Humans; Kainic Acid; Luminescent Proteins; Microscopy, Confocal; Mutation; Neurons; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Receptors, Kainic Acid; Serine; SUMO-1 Protein; Sumoylation | 2011 |
Functional evidence for D-serine inhibition of non-N-methyl-D-aspartate ionotropic glutamate receptors in retinal neurons.
Topics: Adamantane; Animals; Calcium; Guinea Pigs; Kainic Acid; Patch-Clamp Techniques; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Retinal Neurons; Serine | 2012 |
Kainic acid-induced seizures modulate Akt (SER473) phosphorylation in the hippocampus of dopamine D2 receptor knockout mice.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; beta Catenin; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Dishevelled Proteins; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Dopamine D2; Seizures; Serine; Transcription, Genetic; Wnt Signaling Pathway | 2013 |
Glutamate receptor 1 phosphorylation at serine 831 and 845 modulates seizure susceptibility and hippocampal hyperexcitability after early life seizures.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Disease Models, Animal; Disease Susceptibility; Disks Large Homolog 4 Protein; Excitatory Postsynaptic Potentials; Gene Knock-In Techniques; Guanylate Kinases; Hippocampus; Humans; Hypoxia; Kainic Acid; Membrane Proteins; Mice; Mice, Inbred C57BL; Pentylenetetrazole; Phosphorylation; Receptors, AMPA; Seizures; Serine | 2012 |
GSK-3β is Dephosphorylated by PP2A in a Leu309 Methylation-Independent Manner.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Kainic Acid; Leucine; Luminescent Proteins; Male; Methylation; Mice; Phosphorylation; Protein O-Methyltransferase; Protein Phosphatase 2; RNA, Small Interfering; Serine; tau Proteins | 2016 |
Dynamin-Related Protein 1 Promotes Mitochondrial Fission and Contributes to The Hippocampal Neuronal Cell Death Following Experimental Status Epilepticus.
Topics: Animals; Apoptosis; Caspase 3; Disease Models, Animal; Dynamins; Excitatory Amino Acid Agonists; Functional Laterality; Gene Expression Regulation; Hippocampus; Kainic Acid; Male; Mitochondrial Dynamics; NAD; Neurons; Phosphopyruvate Hydratase; Quinazolinones; Rats; Rats, Sprague-Dawley; Serine; Status Epilepticus | 2016 |
Subcellular Distribution of HDAC1 in Neurotoxic Conditions Is Dependent on Serine Phosphorylation.
Topics: Animals; Histone Deacetylase 1; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neurons; Neurotoxins; Phosphorylation; Serine; Subcellular Fractions; Tissue Distribution | 2017 |
P2 × 7 Receptor Inhibits Astroglial Autophagy via Regulating FAK- and PHLPP1/2-Mediated AKT-S473 Phosphorylation Following Kainic Acid-Induced Seizures.
Topics: Adaptor Proteins, Signal Transducing; Animals; Astrocytes; Autophagy; Carrier Proteins; Focal Adhesion Protein-Tyrosine Kinases; Heat-Shock Proteins; Kainic Acid; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphoprotein Phosphatases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rapamycin-Insensitive Companion of mTOR Protein; Receptors, Purinergic P2X7; Seizures; Serine; Signal Transduction; TOR Serine-Threonine Kinases | 2020 |
PLPP/CIN-mediated DARPP-32 serine 97 dephosphorylation delays the seizure onset in response to kainic acid in the mouse hippocampus.
Topics: Animals; Casein Kinase II; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Hippocampus; Kainic Acid; Mice; Phosphates; Phosphoproteins; Phosphorylation; Protein Phosphatase 1; Pyridoxal; Seizures; Serine | 2022 |