serine and isoxazoles

serine has been researched along with isoxazoles in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.54)18.7374
1990's8 (30.77)18.2507
2000's9 (34.62)29.6817
2010's5 (19.23)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Israel, Y; Shackel, N; Speisky, H; Varghese, G; Wade, D1
Abouakil, N; Lombardo, D; Rogalska, E1
Mego, JL1
Demedts, M; Hoet, PH; Nemery, B; van Klaveren, RJ1
Anderson, ME; Fujii, J; Ikeda, Y; Meister, A; Taniguchi, N1
Fujii, J; Ikeda, Y; Meister, A; Smith, TK; Taniguchi, N1
Bloomer, WD; Damodaran, KM; Hughey, RP; Prezioso, JA; Wang, N1
Oster, T; Siest, G; Thioudellet, C; Wellman, M1
Pickhardt, PA; Ripple, MO; Wilding, G1
Fujimura, HA1
Ikegami, F; Ishikawa, T; Kusama, T; Kusamae-Eguchi, K; Sekine, T; Watanabe, K; Yamamoto, A1
Bordeleau, M; Brooks, KM; Corbett, TJ; de Lannoy, I; Hendrix, JA; Kafka, S; Kamboj, RK; Kapples, KJ; Laws-Ricker, L; Lee, DK; Owolabi, J; Palermo, MG; Rizkalla, G; Shimshock, SJ; Shutske, GM; Tomer, JD; Vargas, HM1
Egebjerg, J; Krogsgaard-Larsen, P; Liljefors, T; Nielsen, MM1
TANAKA, N; UMEZAWA, H1
Bode, AM; Cho, YY; Choi, HS; Dong, Z; He, Z; Ma, WY1
Bizik, F; Glazer, RI; Kozikowski, AP; Mercola, M; Petukhov, PA; Teixeira, JC; Volpe, EA; Wei, ZL; Willson, TM1
Didriksen, M; Kreilgaard, M; Olsen, CK1
Duvall, B; Ferraris, D; Hashimoto, K; Ko, YS; Majer, P; Rojas, C; Thomas, AG; Tsukamoto, T1
Ferraris, D; Fujita, Y; Hashimoto, K; Horio, M; Iyo, M; Kunitachi, S; Tsukamoto, T1
Benson, GM; Bleicher, K; Chen, L; Feng, S; Grether, U; Hong, D; Kuhn, B; Martin, RE; Plancher, JM; Richter, H; Rudolph, MG; Wang, Z; Yang, M; Zhang, Z1
Bae, SJ; Cho, JW; Choi, SR; Gwak, J; Ha, NC; Han, JK; Hwang, SG; Kim, DE; Kim, H; Oh, S; Park, HS; Park, SH1
Gong, N; Lu, JM; Wang, YC; Wang, YX1
Brandon, NJ; Engle, SJ; Jaaro-Peled, H; Rais, R; Rojas, C; Sawa, A; Slusher, BS; Strick, CA; Thomas, AG; Tsukamoto, T; Wozniak, K; Wu, Y1
Alt, J; Ator, NA; Ferraris, D; Hin, N; Rais, R; Rojas, C; Slusher, BS; Thomas, AG; Tsukamoto, T; Wozniak, K; Wu, Y1
Atrakchi-Baranes, D; Biegon, A; Friedman Levi, Y; Kesner, E; Liraz-Zaltsman, S; Rosenblatt, K; Shohami, E; Silva, AJ; Slusher, B1
Du, N; Liu, X; Ma, C; Niu, Y; Piao, F; Wang, H; Yan, Z; Zhang, JJ; Zhao, T; Zhou, L1

Other Studies

26 other study(ies) available for serine and isoxazoles

ArticleYear
Role of hepatic gamma-glutamyltransferase in the degradation of circulating glutathione: studies in the intact guinea pig perfused liver.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:5

    Topics: Animals; Borates; Cysteine; Dipeptides; gamma-Glutamyltransferase; Glutathione; Guinea Pigs; Isoxazoles; Liver; Perfusion; Serine

1990
Human milk bile-salt stimulated lipase: further investigations on the amino-acids residues involved in the catalytic site.
    Biochimica et biophysica acta, 1989, Apr-03, Volume: 1002, Issue:2

    Topics: Acylation; Adsorption; Bile Acids and Salts; Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Chemistry, Physical; Diethyl Pyrocarbonate; Histidine; Humans; Hydrogen Bonding; Isoflurophate; Isoxazoles; Kinetics; Lipase; Micelles; Milk, Human; Phosphorylation; Serine; Spectrophotometry; Structure-Activity Relationship

1989
Stimulation of intralysosomal proteolysis by cysteinyl-glycine, a product of the action of gamma-glutamyl transpeptidase on glutathione.
    Biochimica et biophysica acta, 1985, Aug-16, Volume: 841, Issue:2

    Topics: Animals; Borates; Cysteine; Dipeptides; Enzyme Activation; gamma-Glutamyltransferase; Glutathione; Isoxazoles; Kidney; Liver; Lysosomes; Mice; Peptide Hydrolases; Rats; Serine

1985
Role of gamma-glutamyltransferase in putrescine uptake by rat type II pneumocytes.
    Biochemical pharmacology, 1995, Sep-28, Volume: 50, Issue:7

    Topics: Animals; Borates; Cell Separation; Cell Survival; Cells, Cultured; Copper; Down-Regulation; gamma-Glutamyltransferase; Glutathione; Isoxazoles; Kinetics; Lung; Male; Organometallic Compounds; Phenanthrolines; Putrescine; Rats; Rats, Wistar; Serine

1995
Involvement of Ser-451 and Ser-452 in the catalysis of human gamma-glutamyl transpeptidase.
    The Journal of biological chemistry, 1995, Sep-22, Volume: 270, Issue:38

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Borates; Catalysis; DNA Primers; gamma-Glutamyltransferase; Humans; Isoxazoles; Kinetics; Molecular Sequence Data; Rats; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Swine

1995
Different sites of acivicin binding and inactivation of gamma-glutamyl transpeptidases.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Mar-14, Volume: 92, Issue:6

    Topics: Alanine; Amino Acid Sequence; Animals; Antimetabolites; Base Sequence; Binding Sites; Cloning, Molecular; DNA Primers; gamma-Glutamyltransferase; Humans; Hydroxylamine; Hydroxylamines; Isoxazoles; Kidney; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Point Mutation; Rats; Recombinant Proteins; Restriction Mapping; Serine; Swine; Threonine

1995
Gamma-glutamyltranspeptidase expression regulates the growth-inhibitory activity of the anti-tumor prodrug gamma-L-glutaminyl-4-hydroxy-3-iodobenzene.
    International journal of cancer, 1994, Mar-15, Volume: 56, Issue:6

    Topics: Animals; Antineoplastic Agents; Borates; Cell Division; CHO Cells; Cricetinae; gamma-Glutamyltransferase; Glutamine; Glutathione; Hydrolysis; Isoxazoles; Melanins; Melanoma, Experimental; Mice; Phenols; Prodrugs; Serine; Transfection

1994
Molecular and functional characterization of recombinant human gamma-glutamyltransferase. Coupling of its activity to glutathione levels in V79 cells.
    European journal of biochemistry, 1994, Jun-15, Volume: 222, Issue:3

    Topics: Amino Acid Sequence; Borates; Catalysis; Cell Division; Cell Line; Circular Dichroism; gamma-Glutamyltransferase; Glutathione; Humans; Isoxazoles; Leukotriene C4; Leukotriene D4; Molecular Sequence Data; Oxidation-Reduction; Protein Structure, Secondary; Recombinant Proteins; Serine

1994
Alteration in gamma-glutamyl transpeptidase activity and messenger RNA of human prostate carcinoma cells by androgen.
    Cancer research, 1997, Jun-15, Volume: 57, Issue:12

    Topics: Androgens; Borates; Cell Division; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutathione; Glycylglycine; Humans; Immunohistochemistry; Isoxazoles; Male; Prostatic Neoplasms; RNA, Messenger; Serine; Tumor Cells, Cultured

1997
Saccharomyces cerevisiae MLF3/YNL074C gene, encoding a serine-rich protein of unknown function, determines the level of resistance to the novel immunosuppressive drug leflunomide.
    Biochimica et biophysica acta, 1998, Nov-08, Volume: 1442, Issue:2-3

    Topics: Amino Acid Sequence; Cloning, Molecular; Drug Resistance, Microbial; Fungal Proteins; Immunosuppressive Agents; Isoxazoles; Leflunomide; Molecular Sequence Data; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine

1998
Synthesis and pharmacological activity of O-(5-isoxazolyl)-L-serine.
    Chemical & pharmaceutical bulletin, 2000, Volume: 48, Issue:2

    Topics: Amino Acid Transport System X-AG; Amino Acids; Animals; ATP-Binding Cassette Transporters; Excitatory Amino Acid Antagonists; Indicators and Reagents; Isomerism; Isoxazoles; Pisum sativum; Receptors, Glutamate; Serine; Structure-Activity Relationship; Xenopus

2000
Synthesis and structure-activity relationship of the isoindolinyl benzisoxazolpiperidines as potent, selective, and orally active human dopamine D4 receptor antagonists.
    Chembiochem : a European journal of chemical biology, 2002, Oct-04, Volume: 3, Issue:10

    Topics: Administration, Oral; Animals; Apomorphine; Benzyl Compounds; Dizocilpine Maleate; Dopamine D2 Receptor Antagonists; Indoles; Infusions, Parenteral; Isoxazoles; Piperidines; Prazosin; Rats; Receptors, Dopamine D4; Serine; Spiperone; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity

2002
The selective activation of the glutamate receptor GluR5 by ATPA is controlled by serine 741.
    Molecular pharmacology, 2003, Volume: 63, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Isoxazoles; Models, Molecular; Mutagenesis; Propionates; Receptors, AMPA; Receptors, Kainic Acid; Serine; Xenopus laevis

2003
SYNERGISM OF D-4-AMINO-3-ISOXAZOLIDONE AND O-CARBAMYL-D-SERINE.
    The Journal of antibiotics, 1964, Volume: 17

    Topics: Anti-Bacterial Agents; Bacillus subtilis; Isoxazoles; Mycobacterium; Mycobacterium tuberculosis; Oxazoles; Oxazolidinones; Pharmacology; Research; Serine; Staphylococcus

1964
Regulation of ultraviolet B-induced phosphorylation of histone H3 at serine 10 by Fyn kinase.
    The Journal of biological chemistry, 2005, Jan-28, Volume: 280, Issue:4

    Topics: Animals; Cell Line; Cell Line, Tumor; Dose-Response Relationship, Drug; Genes, Dominant; Histones; Humans; Isoxazoles; Leflunomide; MAP Kinase Signaling System; Mice; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plasmids; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fyn; RNA, Small Interfering; Serine; Signal Transduction; src-Family Kinases; Threonine; Time Factors; Transfection; Ultraviolet Rays

2005
Isoxazolyl-serine-based agonists of peroxisome proliferator-activated receptor: design, synthesis, and effects on cardiomyocyte differentiation.
    Journal of the American Chemical Society, 2004, Dec-29, Volume: 126, Issue:51

    Topics: Animals; Cell Differentiation; Combinatorial Chemistry Techniques; Isoxazoles; Ligands; Mice; Models, Molecular; Myocytes, Cardiac; Peroxisome Proliferator-Activated Receptors; Serine; Structure-Activity Relationship

2004
Positive modulation of glutamatergic receptors potentiates the suppressive effects of antipsychotics on conditioned avoidance responding in rats.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 84, Issue:2

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Benzodiazepines; Clozapine; Conditioning, Psychological; Dioxoles; Drug Synergism; Isoxazoles; Male; Olanzapine; Paliperidone Palmitate; Piperidines; Pyrimidines; Rats; Rats, Wistar; Receptors, AMPA; Risperidone; Serine; Stereoisomerism

2006
Synthesis and biological evaluation of D-amino acid oxidase inhibitors.
    Journal of medicinal chemistry, 2008, Jun-26, Volume: 51, Issue:12

    Topics: Administration, Oral; Animals; Benzoxazoles; Brain; D-Amino-Acid Oxidase; Drug Synergism; Isoxazoles; Male; Rats; Rats, Sprague-Dawley; Serine; Structure-Activity Relationship

2008
Co-administration of a D-amino acid oxidase inhibitor potentiates the efficacy of D-serine in attenuating prepulse inhibition deficits after administration of dizocilpine.
    Biological psychiatry, 2009, Jun-15, Volume: 65, Issue:12

    Topics: Acoustic Stimulation; Amino Acid Oxidoreductases; Animals; Brain Chemistry; Dizocilpine Maleate; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Isoxazoles; Male; Mice; Prefrontal Cortex; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Serine

2009
Identification of an N-oxide pyridine GW4064 analog as a potent FXR agonist.
    Bioorganic & medicinal chemistry letters, 2009, May-01, Volume: 19, Issue:9

    Topics: Binding Sites; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Design; Humans; Hydrogen Bonding; Isoxazoles; Ligands; Models, Chemical; Protein Binding; Receptors, Cytoplasmic and Nuclear; Serine; Tyrosine

2009
Small molecule-based disruption of the Axin/β-catenin protein complex regulates mesenchymal stem cell differentiation.
    Cell research, 2012, Volume: 22, Issue:1

    Topics: Adipocytes; Axin Signaling Complex; beta Catenin; Cell Differentiation; Enzyme Activation; Enzyme Assays; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Humans; Imidazoles; Immunoprecipitation; Isoxazoles; Mesenchymal Stem Cells; Osteoblasts; Phosphorylation; Plasmids; Protein Interaction Mapping; Proteolysis; Serine; Threonine; Transfection; Wnt Signaling Pathway

2012
D-Amino acid oxidase-mediated increase in spinal hydrogen peroxide is mainly responsible for formalin-induced tonic pain.
    British journal of pharmacology, 2012, Volume: 165, Issue:6

    Topics: Analgesics; Animals; Behavior, Animal; D-Amino-Acid Oxidase; Formaldehyde; Hydrogen Peroxide; Hyperalgesia; Isoxazoles; Male; Mice; Pain; Rats; Rats, Wistar; Serine; Spine

2012
Pharmacokinetics of oral D-serine in D-amino acid oxidase knockout mice.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:11

    Topics: Animals; Brain; D-Amino-Acid Oxidase; Female; Half-Life; Humans; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microsomes, Liver; Schizophrenia; Serine

2012
D-Amino-Acid Oxidase Inhibition Increases D-Serine Plasma Levels in Mouse But not in Monkey or Dog.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:6

    Topics: Animals; D-Amino-Acid Oxidase; Dogs; Isoxazoles; Male; Mice; Papio hamadryas; Serine; Species Specificity

2016
Enhancement of Brain d-Serine Mediates Recovery of Cognitive Function after Traumatic Brain Injury.
    Journal of neurotrauma, 2018, 07-15, Volume: 35, Issue:14

    Topics: Animals; Brain Injuries, Traumatic; Cognition; Cognition Disorders; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate; Recovery of Function; Serine

2018
Accumulation and metabolism of pyroxasulfone in tomato seedlings.
    Ecotoxicology and environmental safety, 2023, Apr-01, Volume: 254

    Topics: Chromatography, Liquid; Isoxazoles; Seedlings; Serine; Solanum lycopersicum; Sulfhydryl Compounds; Tandem Mass Spectrometry

2023