serine has been researched along with h 89 in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (12.24) | 18.2507 |
| 2000's | 33 (67.35) | 29.6817 |
| 2010's | 10 (20.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blumenstein, Y; Dascal, N; Lotan, I; Perets, T; Shistik, E | 1 |
| Downing, JR; Garcia, JV; Luo, T | 1 |
| Aizman, O; Aizman, R; Aperia, A; Cheng, XJ; Fisone, G; Greengard, P; Levenson, R | 1 |
| Amato, SF; Chiles, TC; Hirano, T; Nakajima, K | 1 |
| Cottom, JE; DeManno, DA; Hunzicker-Dunn, M; Kline, MP; Maizels, ET; Peters, CA | 1 |
| Brown, EJ; Wang, J | 1 |
| Lesslauer, W; Mary, JL; Tomás-Zuber, M | 1 |
| Cai, Z; Conn, PJ; Hubalek, F; Macek, TA; Murphy, TJ; Pohl, J; Schaffhauser, H | 1 |
| Alessi, DR; Arthur, JS; Deak, M; Kieloch, A; Lain, S; Lizcano, JM; Morrice, N; Sapkota, GP; Williams, MR | 1 |
| Bode, AM; Dong, Z; Goto, H; Inagaki, M; Jansen, C; Ma, WY; She, QB; Zhong, S | 1 |
| Kabashima, T; Kawaguchi, T; Takenoshita, M; Uyeda, K | 1 |
| Bakó, E; Bíró, T; Czifra, G; Felszeghy, S; Gergely, P; Módis, L; Szucs, K; Zákány, R | 1 |
| Mattiazzi, A; Mundiña-Weilenmann, C; Said, M; Vittone, L | 1 |
| Hepler, JR; Hollinger, S; Ramineni, S | 1 |
| De Wilde, G; Haegeman, G; Van Damme, P; Vanden Berghe, W; Vermeulen, L | 1 |
| Fang, H; Flier, JS; Masuzaki, H; Shinyama, H | 1 |
| Dumaz, N; Marais, R | 1 |
| Cabrera, M; Hidalgo, J; Martín, ME; Muñiz, M; Vega, L; Velasco, A | 1 |
| Malissein, E; Ratinaud, MH; Troutaud, D; Verdier, M | 1 |
| Chen, J; Grammatopoulos, DK; Hillhouse, EW; Levine, MA; Papadopoulou, N; Randeva, HS | 1 |
| Cheung, JY; Deng, J; Eaton, P; Fuller, W; James, AF; Moorman, JR; Shattock, MJ; Silverman, Bd | 1 |
| Aperia, A; Frøkiaer, J; Nejsum, LN; Nielsen, S; Zelenina, M | 1 |
| Adamy, C; Ait-Mamar, B; Bouabdallah, A; Cailleret, M; Candiani, G; Defer, N; Duvaldestin, P; Pavoine, C; Pecker, F; Rucker-Martin, C | 1 |
| DeAngelo, D; Galinsky, I; Liu, L; Sternberg, D; Stone, R; Tang, L; Yang, X | 1 |
| Delghandi, MP; Johannessen, M; Moens, U | 1 |
| Misra, UK; Pizzo, SV | 1 |
| Bost, PE; Cayla, X; Dessauge, F; Garcia, A; Guergnon, J; Langsley, G; Rebollo, A; Traincard, F | 1 |
| Beis, I; Gaitanaki, C; Kefaloyianni, E | 1 |
| DeVries, GH; Muja, N; Nelson, JK | 1 |
| Fukunaga, K; Matsuzaki, K; Mimaki, Y; Miyazaki, K; Moriguchi, S; Nakata, N; Ohizumi, Y; Sakai, S; Sashida, Y; Yamakuni, T; Yawo, H; Yokosuka, A | 1 |
| Beck, IM; Bougarne, N; De Bosscher, K; Haegeman, G; Vanden Berghe, W; Vander Cruyssen, B; Vermeulen, L | 1 |
| Lee, CH; Liou, HH; Lu, KL; Shen, YC; Tsai, MC | 1 |
| Hammond, RS; Hoffman, DA; Lin, L; Sidorov, MS; Wikenheiser, AM | 1 |
| Birnbaum, Y; Lin, Y; Perez-Polo, JR; Tieu, BC; Uretsky, BF; Ye, Y; Ye, Z | 1 |
| Benlhabib, H; Liu, D; Mendelson, CR | 1 |
| Hu, XD; Liu, XH; Xie, QJ; Yang, HB; Yang, X | 1 |
| He, J; Jiang, H; Pu, S; Xu, C; Xu, G; Zhai, W; Zu, L | 1 |
| Hayashi, H; Sudo, T | 1 |
| Arun, P; Brown, MS; Chen, Z; Ehsanian, R; Van Waes, C | 1 |
| Chang, HP; Hsueh, YP; Huang, TN | 1 |
| Davie, JR; Drobic, B; Kung, SK; Pérez-Cadahía, B; Yu, J | 1 |
| Cignarelli, A; De Stefano, F; Giorgino, F; Labarbuta, R; Laviola, L; Leonardini, A; Marchetti, P; Melchiorre, M; Natalicchio, A; Orlando, MR; Perrini, S | 1 |
| Jin, Q; Mulder, KM; Zhong, Y | 1 |
| Guo, X; Hao, S; Li, J; Liu, Y; Wu, H; Zheng, Q | 1 |
| Liu, C; Liu, Y; Luan, Z; Wang, E; Wu, D; Yu, B | 1 |
| Choi, HK; Choi, KC; Han, EJ; Jun, WJ; Lee, J; Lee, YH; Oh, HJ; Park, SY; Yoon, HG | 1 |
| Choi, JK; Choi, YH; Chun, C; Jeong, HG; Jeong, HM; Jeong, TC; Kim, JH; Lee, KY; Li, H; Yeo, CY | 1 |
| Ichinose, H; Kawahata, I; Ohtaku, S; Tomioka, Y; Yamakuni, T | 1 |
| Chen, Y; Falero-Perez, JM; Kim, SF; Mathias, L | 1 |
49 other study(ies) available for serine and h 89
| Article | Year |
|---|---|
A potential site of functional modulation by protein kinase A in the cardiac Ca2+ channel alpha 1C subunit.
Topics: Animals; Base Sequence; Calcium Channels; Calcium Channels, L-Type; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Ion Channel Gating; Isoquinolines; Molecular Sequence Data; Muscle Proteins; Mutagenesis, Site-Directed; Myocardium; Oocytes; Patch-Clamp Techniques; Phosphorylation; Protein Processing, Post-Translational; Rabbits; Recombinant Fusion Proteins; Serine; Sulfonamides; Thionucleotides; Xenopus laevis | 1996 |
Induction of phosphorylation of human immunodeficiency virus type 1 Nef and enhancement of CD4 downregulation by phorbol myristate acetate.
Topics: CD4 Antigens; CD4-Positive T-Lymphocytes; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Inhibitors; Gene Products, nef; HIV-1; Humans; Indoles; Isoquinolines; Maleimides; nef Gene Products, Human Immunodeficiency Virus; Phosphorylation; Phytohemagglutinins; Protein Kinase C; Recombinant Fusion Proteins; Serine; Sulfonamides; Tetradecanoylphorbol Acetate | 1997 |
PKA-mediated phosphorylation and inhibition of Na(+)-K(+)-ATPase in response to beta-adrenergic hormone.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Alanine; Animals; Cell Line; Colforsin; COS Cells; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoproterenol; Isoquinolines; Macromolecular Substances; Mutagenesis, Site-Directed; Okadaic Acid; Phosphorylation; Point Mutation; Rats; Recombinant Proteins; Rubidium; Serine; Sodium-Potassium-Exchanging ATPase; Spodoptera; Sulfonamides; Transfection | 1997 |
Transcriptional regulation of the junB gene in B lymphocytes: role of protein kinase A and a membrane Ig-regulated protein phosphatase.
Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Genes, jun; Isoquinolines; Lymphoma, B-Cell; Mice; Peptides; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Proto-Oncogene Proteins c-jun; Receptors, Antigen, B-Cell; Serine; Sulfonamides; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured | 1997 |
Follicle-stimulating hormone promotes histone H3 phosphorylation on serine-10.
Topics: Animals; Cell Differentiation; Cell Extracts; Cells, Cultured; Culture Media, Serum-Free; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Female; Follicle Stimulating Hormone; Granulosa Cells; Histones; Isoquinolines; Peptide Mapping; Phosphoamino Acids; Phosphoproteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Serine; Solubility; Sulfonamides | 1999 |
Immune complex-induced integrin activation and L-plastin phosphorylation require protein kinase A.
Topics: Amino Acid Sequence; Antigen-Antibody Complex; Carbazoles; Cell Adhesion; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indoles; Isoquinolines; Macrophage-1 Antigen; Membrane Glycoproteins; Microfilament Proteins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Pyrroles; Receptors, IgG; Serine; Sulfonamides; Tetradecanoylphorbol Acetate | 1999 |
Control sites of ribosomal S6 kinase B and persistent activation through tumor necrosis factor.
Topics: Amino Acid Sequence; Catalytic Domain; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; HeLa Cells; Humans; Indoles; Insulin; Ionomycin; Isoquinolines; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Recombinant Proteins; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Substrate Specificity; Sulfonamides; Tetradecanoylphorbol Acetate; Threonine; Tumor Necrosis Factor-alpha | 2000 |
cAMP-dependent protein kinase inhibits mGluR2 coupling to G-proteins by direct receptor phosphorylation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Amino Acid Sequence; Animals; Anticonvulsants; CHO Cells; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclopropanes; Dentate Gyrus; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoquinolines; Molecular Sequence Data; Mutagenesis; Neurons; Perforant Pathway; Phosphorylation; Protein Binding; Rats; Receptors, Metabotropic Glutamate; Serine; Sulfonamides; Transfection | 2000 |
Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line; Cloning, Molecular; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cysteine; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Glutathione Transferase; Humans; Immunoblotting; Isoquinolines; Mevalonic Acid; Mice; Models, Biological; Mutation; Peutz-Jeghers Syndrome; Phosphorylation; Precipitin Tests; Protein Prenylation; Protein Serine-Threonine Kinases; Rats; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfonamides; Time Factors; Transfection | 2001 |
Ultraviolet B-induced phosphorylation of histone H3 at serine 28 is mediated by MSK1.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chromatin; Enzyme Activation; Enzyme Inhibitors; Epidermis; Histones; Isoquinolines; Mice; Nucleosomes; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Sulfonamides; Transfection; Ultraviolet Rays | 2001 |
Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein.
Topics: Amino Acid Sequence; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Binding Sites; Bucladesine; Cantharidin; Carbohydrate Metabolism; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glucose; Helix-Loop-Helix Motifs; Isoquinolines; Leucine Zippers; Male; Mice; Molecular Sequence Data; Mutagenesis; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Pyruvate Kinase; Rats; Rats, Sprague-Dawley; Response Elements; Serine; Subcellular Fractions; Sulfonamides; Threonine; Transcription Factors; Transcription, Genetic | 2001 |
Protein phosphatase 2A is involved in the regulation of protein kinase A signaling pathway during in vitro chondrogenesis.
Topics: Animals; Cartilage; Cell Differentiation; Cell Division; Cells, Cultured; Chick Embryo; Chondrocytes; Chondrogenesis; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoquinolines; Limb Buds; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Serine; Signal Transduction; Sulfonamides; Threonine; Time Factors | 2002 |
The relative relevance of phosphorylation of the Thr(17) residue of phospholamban is different at different levels of beta-adrenergic stimulation.
Topics: Adrenergic beta-Agonists; Animals; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoproterenol; Isoquinolines; Male; Myocardial Contraction; Myocardium; Phosphorus Radioisotopes; Phosphorylation; Rats; Rats, Wistar; Serine; Sulfonamides; Threonine | 2002 |
Phosphorylation of RGS14 by protein kinase A potentiates its activity toward G alpha i.
Topics: Amino Acid Substitution; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Isoquinolines; Molecular Mimicry; Phosphorylation; Protein Subunits; Proto-Oncogene Proteins; Rats; Recombinant Proteins; RGS Proteins; Serine; Signal Transduction; Sulfonamides; Threonine; Tumor Cells, Cultured | 2003 |
Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1).
Topics: Animals; Butadienes; Cell Line; Cell Nucleus; Enzyme Inhibitors; Escherichia coli; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Isoquinolines; L Cells; Mice; Mice, Mutant Strains; Mitogen-Activated Protein Kinases; Models, Biological; Mutation; NF-kappa B; Nitriles; Phosphorylation; Protein Subunits; Pyridines; Recombinant Proteins; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Sulfonamides; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2003 |
Regulation of melanocortin-4 receptor signaling: agonist-mediated desensitization and internalization.
Topics: Agouti-Related Protein; alpha-MSH; Animals; Arrestins; beta-Adrenergic Receptor Kinases; beta-Arrestins; Colforsin; COS Cells; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dynamin I; Endocytosis; Enzyme Inhibitors; Gene Expression; Green Fluorescent Proteins; Hemagglutinins; Humans; Hypothalamus, Middle; Indicators and Reagents; Isoquinolines; Kidney; Luminescent Proteins; Mice; Peptide Fragments; Phosphorylation; Receptor, Melanocortin, Type 4; Receptors, Corticotropin; Serine; Signal Transduction; Sulfonamides; Threonine | 2003 |
Protein kinase A blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras.
Topics: 14-3-3 Proteins; 3T3 Cells; Animals; Binding Sites; Cell Culture Techniques; Cell Membrane; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Isoquinolines; Mice; Peptides; Phosphorylation; Precipitin Tests; Protein Binding; Proto-Oncogene Proteins c-raf; RNA Interference; Serine; Signal Transduction; Sulfonamides; Time Factors; Tyrosine 3-Monooxygenase | 2003 |
The retrieval function of the KDEL receptor requires PKA phosphorylation of its C-terminus.
Topics: Adenosine Triphosphate; ADP-Ribosylation Factors; Animals; Aspartic Acid; Cell Compartmentation; Cells, Cultured; Chlorocebus aethiops; Cloning, Molecular; COS Cells; Cyclic AMP-Dependent Protein Kinases; Endoplasmic Reticulum; Fluorescent Antibody Technique; Golgi Apparatus; GTPase-Activating Proteins; Guanosine Triphosphate; Isoquinolines; Mutation; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Protein Transport; Receptors, Peptide; Serine; Signal Transduction; Sulfonamides | 2003 |
Changes in bad phosphorylation are correlated with BCR-induced apoptosis of WEHI-231 immature B cells.
Topics: 14-3-3 Proteins; Animals; Apoptosis; B-Lymphocytes; bcl-Associated Death Protein; bcl-X Protein; Carrier Proteins; Cells, Cultured; Chromones; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Immunoglobulin M; Isoquinolines; Lymphoma, B-Cell; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Receptors, Antigen, B-Cell; Serine; Sulfonamides; Tyrosine 3-Monooxygenase | 2003 |
Protein kinase A-induced negative regulation of the corticotropin-releasing hormone R1alpha receptor-extracellularly regulated kinase signal transduction pathway: the critical role of Ser301 for signaling switch and selectivity.
Topics: Cells, Cultured; Corticotropin-Releasing Hormone; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Female; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Isoquinolines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Myometrium; Phosphorylation; Pregnancy; Protein Kinase C; Receptors, Corticotropin-Releasing Hormone; Serine; Signal Transduction; Sulfonamides; Urocortins | 2004 |
Serine 68 phosphorylation of phospholemman: acute isoform-specific activation of cardiac Na/K ATPase.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Guinea Pigs; Heart Ventricles; Isoquinolines; Membrane Proteins; Microscopy, Fluorescence; Myocytes, Cardiac; Patch-Clamp Techniques; Phosphoproteins; Phosphorylation; Protein Isoforms; Serine; Sodium-Potassium-Exchanging ATPase; Sulfonamides | 2005 |
Bidirectional regulation of AQP2 trafficking and recycling: involvement of AQP2-S256 phosphorylation.
Topics: Animals; Antibody Specificity; Aquaporin 2; Aquaporins; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dogs; Dopamine; Endocytosis; Isoquinolines; Kidney; Male; Phosphorylation; Protein Kinase Inhibitors; Protein Transport; Rats; Rats, Sprague-Dawley; Renal Agents; Serine; Sulfonamides; Vasopressins | 2005 |
The cytosolic phospholipase A2 pathway, a safeguard of beta2-adrenergic cardiac effects in rat.
Topics: Adenylyl Cyclases; Animals; Calcium; Calcium-Transporting ATPases; Caveolin 1; Caveolin 3; Caveolins; Cell Membrane; Cyclic AMP-Dependent Protein Kinases; Cytosol; Enzyme Inhibitors; Ethanolamines; Immunoblotting; Immunohistochemistry; Indoles; Isoquinolines; Lysophospholipase; Microscopy, Confocal; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Pertussis Toxin; Phospholipases A; Phospholipases A2; Phosphorylation; Rats; Receptors, Adrenergic, beta-2; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine; Sulfonamides; Time Factors | 2005 |
The FLT3 internal tandem duplication mutation prevents apoptosis in interleukin-3-deprived BaF3 cells due to protein kinase A and ribosomal S6 kinase 1-mediated BAD phosphorylation at serine 112.
Topics: Amino Acid Sequence; Animals; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Butadienes; Carrier Proteins; Cyclic AMP-Dependent Protein Kinases; Drug Synergism; Enzyme Activation; fms-Like Tyrosine Kinase 3; Hematopoietic Stem Cells; Interleukin-3; Isoquinolines; MAP Kinase Signaling System; Mice; Molecular Sequence Data; Mutation; Nitriles; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptor Protein-Tyrosine Kinases; Ribosomal Protein S6 Kinases, 90-kDa; RNA Interference; Serine; Sulfonamides; Tandem Repeat Sequences; Tyrphostins | 2005 |
The cAMP signalling pathway activates CREB through PKA, p38 and MSK1 in NIH 3T3 cells.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Isoquinolines; Mice; Mutation; NIH 3T3 Cells; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Signal Transduction; Sulfonamides; Transcription, Genetic | 2005 |
Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: effects of silencing CREB gene expression on Akt activation.
Topics: Androstadienes; Animals; bcl-Associated Death Protein; Blotting, Western; Cell Count; Cell Proliferation; Chromones; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Gene Silencing; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Immunoprecipitation; Isoquinolines; Macrophages; Mice; Mice, Inbred C57BL; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; rap1 GTP-Binding Proteins; RNA Interference; RNA, Double-Stranded; Serine; Signal Transduction; Sulfonamides; Threonine; Thymidine; Time Factors; Up-Regulation; Wortmannin; X-Linked Inhibitor of Apoptosis Protein | 2005 |
A PKA survival pathway inhibited by DPT-PKI, a new specific cell permeable PKA inhibitor, is induced by T. annulata in parasitized B-lymphocytes.
Topics: Amino Acid Sequence; Animals; Apoptosis; B-Lymphocytes; bcl-Associated Death Protein; Carbazoles; Cattle; Cell Proliferation; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Indoles; Isoquinolines; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrroles; Recombinant Fusion Proteins; Serine; Sulfonamides; Theileria annulata; Theileriasis; Up-Regulation | 2006 |
ERK1/2 and p38-MAPK signalling pathways, through MSK1, are involved in NF-kappaB transactivation during oxidative stress in skeletal myoblasts.
Topics: Animals; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Flavonoids; Hydrogen Peroxide; I-kappa B Proteins; Imidazoles; Immunoblotting; Isoquinolines; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Myoblasts, Skeletal; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Ribosomal Protein S6 Kinases, 90-kDa; Serine; src-Family Kinases; Sulfonamides | 2006 |
Schwann cells express IP prostanoid receptors coupled to an elevation in intracellular cyclic AMP.
Topics: Analysis of Variance; Animals; Animals, Newborn; Calcium; Cell Proliferation; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epoprostenol; Gene Expression Regulation; Intracellular Fluid; Isoquinolines; Phosphorylation; Platelet Aggregation Inhibitors; Rats; Receptors, Prostaglandin; RNA, Messenger; Schwann Cells; Sciatic Nerve; Serine; Sulfonamides | 2007 |
Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus.
Topics: Action Potentials; Animals; Butadienes; Cells, Cultured; Citrus; Cyclic AMP-Dependent Protein Kinases; Flavones; Fruit; Glutamic Acid; Hippocampus; Isoquinolines; MAP Kinase Kinase Kinases; Mice; Neurons; Nitriles; Nootropic Agents; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Serine; Sulfonamides; Synaptic Transmission; Time Factors; Tissue Culture Techniques | 2008 |
Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kappaB inhibition.
Topics: Cell Line; Cytokines; Cytoplasm; Enzyme Induction; Exportin 1 Protein; Gene Expression Regulation; Glucocorticoids; Histones; Humans; Inflammation; Isoquinolines; Karyopherins; Ligands; Phosphorylation; Promoter Regions, Genetic; Protein Transport; Receptors, Cytoplasmic and Nuclear; Receptors, Glucocorticoid; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Subcellular Fractions; Sulfonamides; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2008 |
d-Amphetamine inhibits inwardly rectifying potassium channels in Xenopus oocytes expression system.
Topics: Animals; Carbazoles; Dextroamphetamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Enzyme Inhibitors; Female; Isoquinolines; Membrane Potentials; Microinjections; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Pyrroles; Serine; Sulfonamides; Xenopus | 2008 |
Protein kinase a mediates activity-dependent Kv4.2 channel trafficking.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Green Fluorescent Proteins; Hippocampus; Isoquinolines; Mutation; Neurons; Phosphorylation; Protein Transport; Rats; Rats, Sprague-Dawley; Serine; Shal Potassium Channels; Sulfonamides; Transfection | 2008 |
Phosphorylation of 5-lipoxygenase at ser523 by protein kinase A determines whether pioglitazone and atorvastatin induce proinflammatory leukotriene B4 or anti-inflammatory 15-epi-lipoxin a4 production.
Topics: Animals; Arachidonate 5-Lipoxygenase; Atorvastatin; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Heptanoic Acids; Immunologic Factors; Isoquinolines; Leukotriene B4; Lipoxins; Male; Myocardium; Phosphorylation; Pioglitazone; Pyrroles; Rats; Rats, Sprague-Dawley; Serine; Sulfonamides; Thiazolidinediones | 2008 |
cAMP enhances estrogen-related receptor alpha (ERRalpha) transcriptional activity at the SP-A promoter by increasing its interaction with protein kinase A and steroid receptor coactivator 2 (SRC-2).
Topics: Animals; Cell Nucleus; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; ERRalpha Estrogen-Related Receptor; Fetus; Genome, Human; Humans; Isoquinolines; Lung; Mice; Nuclear Receptor Coactivator 2; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Transport; Pulmonary Surfactant-Associated Protein A; Receptors, Estrogen; Response Elements; Serine; Sulfonamides; Threonine; Transcription, Genetic | 2009 |
Peripheral inflammation increased the synaptic expression of NMDA receptors in spinal dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Freund's Adjuvant; Functional Laterality; Gene Expression Regulation; Inflammation; Isoquinolines; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Pain Measurement; Posterior Horn Cells; Protein Kinase Inhibitors; Receptors, N-Methyl-D-Aspartate; Serine; Spinal Cord; Subcellular Fractions; Sulfonamides; Synapses | 2009 |
Direct effect of glucocorticoids on lipolysis in adipocytes.
Topics: Adipocytes; Adipose Tissue; Animals; Cyclic Nucleotide Phosphodiesterases, Type 3; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucocorticoids; Isoquinolines; Lipolysis; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Serine; Sulfonamides | 2009 |
Effects of the cAMP-elevating agents cilostamide, cilostazol and forskolin on the phosphorylation of Akt and GSK-3beta in platelets.
Topics: Animals; Binding Sites; Blood Platelets; Cilostazol; Colforsin; Collagen; Cyclic AMP; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; In Vitro Techniques; Isoquinolines; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinolones; Rats; Rats, Sprague-Dawley; Serine; Sulfonamides; Tetrazoles | 2009 |
Nuclear NF-kappaB p65 phosphorylation at serine 276 by protein kinase A contributes to the malignant phenotype of head and neck cancer.
Topics: Carcinoma, Squamous Cell; Cell Cycle; Cell Nucleus; Cell Proliferation; Cyclic AMP-Dependent Protein Kinases; Head and Neck Neoplasms; Humans; Isoquinolines; Mucous Membrane; Phenotype; Phosphorylation; Protein Kinase Inhibitors; Protein Transport; RNA, Small Interfering; Serine; Sulfonamides; Transcription Factor RelA; Tumor Cells, Cultured | 2009 |
CASK phosphorylation by PKA regulates the protein-protein interactions of CASK and expression of the NMDAR2b gene.
Topics: Animals; Brain; Cell Line; Cricetinae; Cricetulus; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disks Large Homolog 4 Protein; Enzyme Inhibitors; Gene Expression Regulation; Guanylate Kinases; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Isoquinolines; Membrane Proteins; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Neuroblastoma; Neurons; Phosphoproteins; Phosphorylation; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Sulfonamides; Syndecan-2; T-Box Domain Proteins; Tetrodotoxin; Threonine; Transfection; Up-Regulation; Zonula Occludens-1 Protein | 2010 |
Promoter chromatin remodeling of immediate-early genes is mediated through H3 phosphorylation at either serine 28 or 10 by the MSK1 multi-protein complex.
Topics: 14-3-3 Proteins; Acetylation; Animals; Cell Line; Chromatin Assembly and Disassembly; Extracellular Signal-Regulated MAP Kinases; Gene Knockout Techniques; Genes, Immediate-Early; Histones; Isoquinolines; MAP Kinase Signaling System; Mice; Nucleosomes; Phosphorylation; Promoter Regions, Genetic; Protein Kinase Inhibitors; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Sulfonamides; Transcription, Genetic | 2010 |
Exendin-4 prevents c-Jun N-terminal protein kinase activation by tumor necrosis factor-alpha (TNFalpha) and inhibits TNFalpha-induced apoptosis in insulin-secreting cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Enzyme Activation; Exenatide; Humans; Hypoglycemic Agents; I-kappa B Proteins; Immunoblotting; Insulin Receptor Substrate Proteins; Insulin-Secreting Cells; Isoquinolines; JNK Mitogen-Activated Protein Kinases; NF-KappaB Inhibitor alpha; Peptides; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Serine; Sulfonamides; Time Factors; Tumor Necrosis Factor-alpha; Venoms | 2010 |
Requirement for protein kinase A in the phosphorylation of the TGFβ receptor-interacting protein km23-1 as a component of TGFβ downstream effects.
Topics: Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cytoplasmic Dyneins; Fibronectins; Genes, Reporter; HEK293 Cells; Humans; Isoquinolines; Luciferases; Phosphorylation; Protein Interaction Mapping; Receptor Cross-Talk; Receptors, Transforming Growth Factor beta; Serine; Smad2 Protein; Sulfonamides; Transcriptional Activation; Transfection; Transforming Growth Factor beta | 2013 |
Rapamycin increases pCREB, Bcl-2, and VEGF-A through ERK under normoxia.
Topics: Antibiotics, Antineoplastic; Blotting, Western; Butadienes; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Humans; Isoquinolines; Nitriles; Oxygen; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Serine; Sirolimus; Sulfonamides; Up-Regulation; Vascular Endothelial Growth Factor A | 2013 |
Ser 15 of WEE1B is a potential PKA phosphorylation target in G2/M transition in one-cell stage mouse embryos.
Topics: Amino Acid Substitution; Animals; Cell Cycle Proteins; Cell Division; Cyclic AMP-Dependent Protein Kinases; Embryo, Mammalian; Female; G2 Phase; Isoquinolines; Male; Mice; Mitosis; Phosphorylation; Protein-Tyrosine Kinases; Serine; Sulfonamides | 2013 |
PKA negatively regulates PP2Cβ to activate NF-κB-mediated inflammatory signaling.
Topics: Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Stability; Gene Expression Regulation, Enzymologic; HEK293 Cells; Humans; Inflammation; Intracellular Signaling Peptides and Proteins; Isoquinolines; NF-kappa B; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2C; Proteolysis; Serine; Signal Transduction; Sulfonamides; Tumor Necrosis Factor-alpha; Ubiquitin | 2013 |
Protein kinase a phosphorylates Dlx3 and regulates the function of Dlx3 during osteoblast differentiation.
Topics: Amino Acid Substitution; Animals; Bone Morphogenetic Protein 2; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; HEK293 Cells; Homeodomain Proteins; Humans; Isoquinolines; Mice; Osteoblasts; Phosphorylation; Protein Stability; Serine; Sulfonamides; Transcription Factors | 2014 |
Dopamine or biopterin deficiency potentiates phosphorylation at (40)Ser and ubiquitination of tyrosine hydroxylase to be degraded by the ubiquitin proteasome system.
Topics: Animals; Biopterins; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Cysteine Proteinase Inhibitors; Dopamine; Gene Expression Regulation; Isoquinolines; Leupeptins; Mesencephalon; Neurons; PC12 Cells; Phosphorylation; Primary Cell Culture; Proteasome Endopeptidase Complex; Proteolysis; Rats; Receptors, Dopamine D2; Serine; Signal Transduction; Sulfonamides; Tyrosine 3-Monooxygenase; Ubiquitin; Ubiquitination | 2015 |
PKA-mediated phosphorylation of Dexras1 suppresses iron trafficking by inhibiting S-nitrosylation.
Topics: Adiponectin; Amino Acid Sequence; Animals; Biological Transport; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; HEK293 Cells; Humans; Immunoblotting; Iron; Isoquinolines; Mice, Knockout; Mutation, Missense; Neurons; Nitric Oxide; Phosphorylation; Protein Kinase Inhibitors; ras Proteins; Sequence Homology, Amino Acid; Serine; Sulfonamides | 2015 |