serine has been researched along with glycine in 2432 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1155 (47.49) | 18.7374 |
| 1990's | 353 (14.51) | 18.2507 |
| 2000's | 495 (20.35) | 29.6817 |
| 2010's | 312 (12.83) | 24.3611 |
| 2020's | 117 (4.81) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Dean, KE; Klein, G; Renaudet, O; Reymond, JL | 1 |
| Cígler, P; Hoffman, HE; Jirásková, J; Konvalinka, J; Sanda, M; Schraml, J | 1 |
| Brandsch, M; Gebauer, S; Laug, L; Schäfer, S; Thondorf, I; Voigt, V; Zebisch, K | 1 |
| Hikichi, M; Iida, S | 1 |
| Gründig, E; Raheem, KA; Salvenmoser, F; Schedl, R; Weiss, J | 1 |
| Kuriyama, K; Yoneda, Y | 1 |
| Clark, PI; Lowe, G | 1 |
| Corrochano, G; DeFeudis, FV; Orensanz Munoz, LM; Sanchez del Alamo, MS; Vidal, MA | 1 |
| Chibata, I; Ema, M; Kakimoto, T | 1 |
| Charmantier, G; Charmantier, M; Jeuniaux, C; Voss-Foucart, MF | 2 |
| Ahnefeld, FW; Dölp, R; Schmitz, E | 1 |
| Ando, T; Bicknell, J; Harris, R; Nyhan, WL; Stern, J | 1 |
| Beck, JV; Hougland, AE | 1 |
| Wheatley, DN | 1 |
| Kilroe-Smith, TA; McLoughlin, JL | 1 |
| Ikegami, T | 1 |
| Chubb, J; Huxtable, R | 1 |
| Chan, PY; Combepine, G; Cossins, EA | 1 |
| Kawai, T; Takagi, K | 1 |
| Ciesielski, L; Koehl, C; Mandel, P; Randrianarisoa, H; Simler, S | 1 |
| Adams, E; Gryder, RM; Lamon, M | 1 |
| Becker, EL; Corcoran, BA; Schiffmann, E; Showell, HV; Smith, E; Ward, PA | 1 |
| Colosi, NW; Harper, AE; Tews, JK | 1 |
| Bradford, HF; Osborne, RH | 2 |
| Coon, CN; Couch, JR | 1 |
| Bachrach, HL; Matheka, HD | 1 |
| Scraba, DG; Ziola, BR | 1 |
| Coon, CN; Cough, JR; Luther, LW | 1 |
| Edminson, PD; Kvamme, E; Reichelt, KL | 1 |
| Ponnamperuma, C; Sweeney, MA; Toste, AP | 1 |
| Beremand, PD; Sojka, GA | 1 |
| Petrochilo, E; Verdiĕre, J | 1 |
| Fager, G; Gustafson, A; Olofsson, SO | 1 |
| Frisell, WR; Lewis, KF; Nemeth, E; Randolph, VM | 1 |
| Bank, WJ; Pfendner, W; Pizer, L | 1 |
| Campbell, R; Hall, PV; Lane, J; Mote, T; Smith, JE | 1 |
| Castric, PA | 1 |
| Benuck, M; Lajtha, A | 1 |
| Miles, EW | 1 |
| Mayhall, CW | 1 |
| Kerebel, B; Menanteau, J; Pieri, J | 1 |
| Brenchley, JE; Stauffer, GV | 3 |
| Blaise, D; Cheung, I; Liu, TN; Mehnert, D; Ogur, M; Paulavicius, I; Wales, W | 1 |
| Dubrow, R; Pizer, LI | 1 |
| Ashman, PU; Newport, GR; Page, CR; Seed, JR; Stibbs, HH | 1 |
| Danchin, A | 1 |
| Csonka, LN | 1 |
| Diekmann, H; Müller, HG | 1 |
| Doran, TI; Mattingly, SJ; Milligan, TW; Straus, DC | 1 |
| Kamoun, P; Parvy, P | 1 |
| Danchin, A; Uzan, M | 2 |
| Ashorn, RG; Krohn, KJ; Marnela, KM; Räsänen, L | 1 |
| Jones, DP; Jörnvall, H; Moldfus, P; Ormstad, K; Orrenius, S; Stead, AH | 1 |
| Berman, PH; Blazer-Yost, B; Segal, S; Steiman, GS; Yudkoff, M | 1 |
| Byram, JE; Senft, AW | 1 |
| Lessie, TG; Wong, HC | 1 |
| Krishna, G; Pohl, LR; Reddy, GB | 1 |
| Biondi, A; Biondi, G; Gallone, U; Padula, P; Pignero, A; Quagliuolo, L | 1 |
| Bürger, U | 1 |
| Davidson, CS; Fernstrom, JD; Hammarstrom-Wiklund, B; Munro, HN; Rand, WM; Wurtman, RJ | 1 |
| Kato, K; Kinoshita, F; Kotani, S; Morisaki, I; Watanabe, Y | 1 |
| Manavalan, P; Ponnuswamy, PK; Srinivasan, AR | 1 |
| Borghetti, AF; Guidotti, GG; Tramacere, M | 1 |
| Dumdey, R; Müller, M; Rapoport, S; Rathmann, J | 2 |
| Liao, LL; Richardson, KE | 2 |
| Roffler-Tarlov, S; Sidman, RL | 1 |
| Chanarin, I; Taguchi, H | 1 |
| Chan, W; Mitch, WE | 1 |
| Cuénod, M; Henke, H | 1 |
| Hamblin, A; Krohn, K; Marnela, KM; Uotila, A | 1 |
| Ikenaka, T; Odani, S | 1 |
| Iliffe, TM; McAdoo, DJ; Novak, RA; Price, CH | 1 |
| Berens, RL; Marr, JJ; Nelson, DJ | 1 |
| Sepúlveda, FV; Smith, MW | 1 |
| Drujan, BD; van Gelder, NM | 1 |
| Laborit, H | 1 |
| Batist, G; Fraser, J; Isenberg, S; Kapoor, V; Newman, EB; Weyman, P | 1 |
| Adley, T; Fraser, J; Kapoor, V; Newman, EB; Potter, R | 1 |
| Anderman, F; Sacks, C; Sherwin, AL; Van Gelder, NM | 1 |
| Holt, RL | 1 |
| Liappis, N | 1 |
| Brown, RH; Collins, N; Merrett, MJ | 1 |
| Anda, LP; Dotchev, D; Liappis, N | 1 |
| Deutsch, HF; Fett, JW | 1 |
| Dikow, A; Lolova, I | 1 |
| Bayley, HS; Chavez, ER | 1 |
| Benkovic, SJ; Schirch, LV; Tatum, CM | 1 |
| Ho, CK; Kern, HL; Ostrove, SA | 1 |
| Giliberti, P; Pignero, A; Tancredi, F | 1 |
| Aoki, TT; Cahill, GF; Ganda, OP; Morrison, RS; Soeldner, JS | 1 |
| Fern, EB; Garlick, PJ | 3 |
| Dufresne, MJ; MacLeod, J; Rogers, J; Sanwal, BD | 1 |
| Cybulski, RL; Fisher, RR | 1 |
| Mauk, MR; Putz, GR; Taketa, F | 1 |
| Hems, R; Krebs, HA | 1 |
| Chapman, DJ; Leech, RM | 1 |
| Liang, CC | 1 |
| Cain, GD; Nollen, PM; Prechel, DP | 1 |
| Chavancy, G; Fournier, A; Garel, JP | 1 |
| Chet, I; Henis, Y; Kritzman, G; Okon, Y | 1 |
| Filipović, N; Fuks, Z; Stern, P | 1 |
| Bauer, B; Ehinger, B | 1 |
| Austen, KF; Boswell, RN; Goetzl, EJ | 1 |
| Benevenga, NJ; Mitchell, AD | 1 |
| Case, GL | 1 |
| Coon, C; Ngo, A | 1 |
| Barbeau, A; Beroniade, V; Breton, G; Geoffroy, G; Lemieux, B; Melançon, S; Shapcott, D | 1 |
| Suzuki, T; Takahashi, E | 1 |
| Counahan, R; Cox, BD; El-Bishti, M; Ogg, CS | 1 |
| Drzeniek, Z; Lisowska, E; Waśniowska, K | 1 |
| Armarego, WL; Milloy, BA; Pendergast, W | 1 |
| Lowe, NR; Robinson, C; Weatherell, JA | 1 |
| Hayes, ML; Hyatt, AT | 1 |
| Dekhuijzen, HM | 1 |
| Barker, JL; Nicoll, RA; Padjen, A | 1 |
| Lee, M; Oxender, DL; Robbins, JC | 1 |
| Chavancy, G; Daillie, J; Garel, JP | 1 |
| Schirch, L | 1 |
| Anderson, R; Jackson, N | 1 |
| Applegarth, DA; Davidson, GF; Evans, ME; Hansen, S; Lock, JE; MacLean, J; MacLeod, PJ; Perry, TL; Urquhart, N | 1 |
| Baños, G; Daniel, PM; Moorhouse, SR; Pratt, OE | 2 |
| Beart, PM; Minchin, MC | 1 |
| Harper, AE; Lutz, J; Tews, JK | 1 |
| Akhtar, M; El-Obeid, HA; Jordan, PM | 1 |
| Bennick, A | 1 |
| Bell, JR; Jones, JH; Webb, TC | 1 |
| Baker, DH; Katz, RS | 1 |
| Balikcioglu, S; Behnken, L; Besser, H; Förster, FJ; Grosshans, E; Neufahrt, A; Nowicki, L | 1 |
| Featherston, WR | 2 |
| Stokstad, EL; Vidal, AJ | 1 |
| Gundalakh, AI; Mel'k, MV; Shcheglova, SA; Volkova, ZA | 1 |
| Black, CC; Brown, RH; Goldstein, LD; Kestler, DP; Mayne, BC; Ray, TB | 1 |
| Amandaraj, MP; Roe, BA | 1 |
| Fein, JE; MacLeod, RA | 1 |
| Fendler, JH; Nagyvary, J; Nome, F | 1 |
| Guadalix, FJ; Ruiz, MC | 1 |
| Bergner, H; Krieghoff, E | 1 |
| Berson, EL; Hayes, KC; Schmidt, SY | 1 |
| Bradford, HF; Richards, CD | 1 |
| Garel, J | 1 |
| Heinrich, D; Kubli, F; Metz, J; Wesch, H | 1 |
| Aydelotte, M; Homandberg, GA; Kuettner, KE; Meyers, R; Tripier, D | 1 |
| Betz, H; Hoch, W; Langosch, D | 1 |
| Bostock, E; Sorrels, TL | 1 |
| Epstein, FH; Heyman, S; Rosen, S; Spokes, K | 1 |
| Faden, AI | 1 |
| Denu, JM; Fitzpatrick, PF | 3 |
| Peeters, BW; Vanderheyden, PM | 1 |
| Hirano, H; Kawamura, M; Kuboki, Y; Mizuno, M; Yamada, H; Zhou, HY | 1 |
| Berg, M; Bruhn, T; Cobo, M; Diemer, NH | 1 |
| Appling, DR; Laude, DA; Pasternack, LB | 2 |
| Fersht, AR; Hirshberg, M; Sancho, J; Serrano, L | 1 |
| Carlson, H; Hillered, L; Ronne-Engström, E; Ungerstedt, U | 1 |
| Lazarewicz, JW; Puka, M; Salińska, E | 1 |
| Battaglia, FC; Cetin, I; Fennessey, PV; Meschia, G; Sparks, JW | 1 |
| Antonini, A; Bellezza, M; Cathala, B; Fellahi, JL; Richard, JP; Thouvenot, JP | 1 |
| Applegarth, DA; Levy, HL; Toone, JR | 1 |
| Bateman, JF; Chan, D; Cole, WG; Hannagan, M; Moeller, I | 1 |
| Futai, M; Iwamoto, A; Maeda, M | 1 |
| Asahara, H; Hasegawa, T; Himeno, H; Shimizu, M; Tamura, K | 1 |
| Ball, MJ; Clarke, PJ; Kettlewell, MG | 1 |
| Davis, CR; Denome, SA; McClung, CR; Page, KM | 1 |
| Fukamachi, I; Hashimoto, H; Kobayashi, J; Morimoto, Y; Nishida, T; Saito, Y; Shibui, T; Shirai, K; Tashiro, J; Yoshida, S | 1 |
| Buttitta, P; Cetta, G; Gomez Lira, M; Mottes, M; Pignatti, PF; Sangalli, A; Tenni, R; Valli, M | 1 |
| Flickinger, CJ; Herr, JC; Klotz, K; Shannon, J; Wright, RM | 1 |
| Bradford, HF; Croucher, MJ | 1 |
| Miller, RF; Slaughter, MM | 1 |
| Peterson, SL | 1 |
| Abe, K; Mizutani, A; Saito, H | 1 |
| Ellingsen, JE; Rykke, M; Sönju, T | 1 |
| Baruah, S; Hegwood, TS; Mallis, LM; Waziri, R | 1 |
| Beart, PM; Conway, EL; Manallack, DT; Mercer, LD; O'Shea, RD | 1 |
| Rykke, M; Sönju, T | 1 |
| Aletras, AJ; Hjerpe, A; Karamanos, NK | 1 |
| Austen, KF; Avraham, H; Avraham, S; Stevens, RL | 1 |
| Derewenda, U; Derewenda, ZS | 1 |
| Futai, M; Hanada, H; Itai, A; Iwamoto, A; Maeda, M; Omote, H; Tomioka, N | 1 |
| Battaglia, FC; Cetin, I; Fennessey, PV; Marconi, AM; Meschia, G; Quick, AN; Sparks, JW | 1 |
| Arbus, GS; Goldberg, DM; Ish-Shalom, N; Macpherson, NA; Moscarello, MA | 1 |
| Chan, D; Cole, WG | 1 |
| Chan, L; Chang, A; Chen, SH; Faustinella, F; Rosseneu, M; Smith, LC; Van Biervliet, JP; Vinaimont, N | 1 |
| Fujita, S; Mawhinney, TP; Peterson, EL; Schweitzer, VG; Woodson, BT | 1 |
| Barbato, G; Bax, A; Ikura, M; Kay, LE; Krinks, M; Spera, S | 1 |
| Cler, JA; Emmett, MR; Iyengar, S; Mick, SJ; Rao, TS; Wood, PL | 2 |
| Gunawan, S; Treiman, DM; Walton, NY | 1 |
| D'Alessio, M; Dobkin, C; Lee, B; Ramirez, F; Rasmussen, M; Vissing, H | 1 |
| Baimbridge, KG; Kessler, M; Lynch, G; Oliver, MW; Shacklock, JA | 1 |
| Brosnan, JT; Brosnan, ME; Dhanakoti, SN; Herzberg, GR | 1 |
| Fell, D; Selhub, J | 1 |
| Keith, R; Patel, J; Salama, A; Thompson, C; Zinkand, WC | 1 |
| LeMaster, DM; Markley, JL; Wang, JF | 1 |
| Appling, DR; Ayo, SH; Kreisberg, JI | 1 |
| Kalbag, SS; Palekar, AG | 1 |
| Joshi-Tope, G; Schirch, V | 1 |
| Fernandez-Checa, JC; Kaplowitz, N; Maddatu, T; Ookhtens, M | 1 |
| Rolfes, RJ; Stauffer, GV; Steiert, JG; Zalkin, H | 1 |
| Bottiglieri, T; Chanarin, I; Deacon, R; Lumb, M; Perry, J | 1 |
| Kishi, J; Prockop, DJ; Westerhausen, A | 1 |
| Drake, MR; Rao, AM; Stipanuk, MH | 1 |
| Boue, J; Kamoun, P; Parvy, P; Rabier, D; Saudubray, JM | 1 |
| Baruah, S; Hegwood, TS; Sherman, AD; Waziri, R | 1 |
| Fedele, E; Fontana, G; Raiteri, M | 1 |
| Collins, GG | 1 |
| Ben-Ari, Y; Cherubini, E; Corradetti, R; Gaiarsa, JL | 1 |
| Costa, E; Danysz, W; Fadda, E; Wroblewski, JT | 2 |
| Cler, JA; Compton, RP; Emmett, MR; Iyengar, S; Mick, S; Rao, TS; Sun, ET; Wood, PL | 1 |
| Hugenholtz, J; Ljungdahl, LG | 1 |
| Larson, J; Lynch, G; Oliver, MW | 1 |
| Braymer, HD; Shinabarger, DL | 1 |
| Garbow, JR; Jacob, GS; Schaefer, J; Stejskal, EO | 1 |
| Hahn, RG | 1 |
| Brosnan, JT; Hall, DE; Jois, M | 1 |
| Mebus, CA; Welsch, F; Working, PK | 1 |
| Kuivaniemi, H; Prockop, DJ; Shikata, H; Tromp, G | 1 |
| Asano, S; Di Donato, A; Manning, JM; Martínez del Pozo, A; Masu, Y; Merola, M; Recsei, P; Tanaka, H; Tanizawa, K; Ueno, H | 1 |
| Billadello, JJ; Fry, ET; Lucore, CL; Monge, JC; Sobel, BE | 1 |
| Luzzatto, L; Mason, PJ; Vulliamy, TJ; Wanachiwanawin, W | 1 |
| Belloque, J; Garcia-Muñoz, MJ; Merinero, B; Pérez-Cerdá, C; Sanz, P; Ugarte, M | 1 |
| Hundal, HS; Rennie, MJ; Watt, PW | 1 |
| Ceserani, R; Gaviraghi, G; Maraia, G; Reggiani, A | 1 |
| Constantinou, CD; Kalia, K; Nielsen, KB; Pack, M; Prockop, DJ | 1 |
| Cheek, JM; Edmond, J; Jones, MR; Tamaki, J; Wu, PY | 1 |
| Brosnan, JT; Hall, B | 1 |
| Algermissen, B; Hampl, H; Nündel, M; Riedel, E; Scigalla, P; Stabell, U | 1 |
| Anzai, Y; Gurpide, E; Holinka, CF; Kuramoto, H; Watanabe, J | 1 |
| Kaback, MM; Neufeld, EF; Paw, BH | 1 |
| Salt, TE | 1 |
| Costa, E; Fadda, E; Lazarewicz, JW; Mazzetta, J; Wroblewski, JT | 1 |
| Nishikawa, T; Shinohara, K; Takahashi, K; Yamazaki, K | 1 |
| Daly, MP; Demediuk, P; Faden, AI | 1 |
| Gottesman, MM; Kakehi, Y; Kioka, N; Komano, T; Pastan, I; Tsubota, J; Ueda, K | 1 |
| D'Alessio, M; Godfrey, M; Hollister, DW; Lee, B; Ramirez, F; Vissing, H | 1 |
| Cler, J; Contreras, PC; Emmett, MR; Iyengar, S; Mick, S; Rao, TS; Wood, PL | 1 |
| Ahl, PL; Khorana, HG; Mogi, T; Rothschild, KJ; Stern, LJ | 1 |
| Craig, G; Fahey, D; McCairns, E; Rowe, PB; Sauer, D | 1 |
| Ravnikar, PD; Somerville, RL | 2 |
| Birch, PJ; Grossman, CJ; Hayes, AG | 1 |
| Askanazi, J; Elwyn, DH; Gil, KM; Gump, FE; Kinney, JM; Starker, PM | 1 |
| Druse, MJ; Rathbun, WE | 1 |
| Hernández, G; Mora, J; Mora, Y | 1 |
| Nakamura, Y; Nakaya, K; Shibayama, T | 1 |
| Mora, F; Peinado, JM | 1 |
| Brosnan, JT; Hall, DE; Hall, MS; Lowry, M | 1 |
| Arrieta, A; Bonilla, E; Prasad, AL | 1 |
| Hoffman, BM; Liang, N; Mauk, AG; Pielak, GJ; Smith, M | 1 |
| Kohno, N; Mitsui, T; Nakajima, H; Shibasaki, T; Yanai, Y | 1 |
| Brosnan, JT; Hall, DE; Lowry, M | 2 |
| Ashworth, DJ; Chen, CS; Mascarenhas, D | 1 |
| Bruinvels, J; Pepplinkhuizen, L | 2 |
| Bruinvels, J; Schouten, MJ | 1 |
| Letarte, J; Ouellet, R; Qureshi, I; Rouleau, T | 1 |
| Elekes, I; Láng, T; Palkovits, M; Patthy, A | 1 |
| Kwon-Chung, KJ; Min, KH | 1 |
| Fujiwara, K; Motokawa, Y; Ohmura, Y; Okamura-Ikeda, K | 1 |
| Austin, FE; Turco, J; Winkler, HH | 1 |
| Garbow, JR; Jacob, GS; Kishore, GM; Schaefer, J | 1 |
| Dudman, NP; Tyrrell, PA; Wilcken, DE | 1 |
| Cabral, JM; Cooney, CL; Klier, J | 1 |
| Corriat, A; Feneant-Thibault, M; Lemonnier, A; Maccario, J; Moatti, N | 1 |
| Newman, EB; Ramotar, D | 1 |
| Beliveau, GP; Brusilow, SW | 1 |
| Kuno, N; Nagatsu, T; Naoi, M; Takahashi, T | 1 |
| Hall, MA; Ogilvy-Stuart, AL; Smythe, PJ; Walker, V | 1 |
| Antonsson, P; Heinegård, D; Oldberg, A | 1 |
| Bonilla-Musoles, F; Jordá, A; Nyhan, WL; Portolés, M; Sweetman, L | 1 |
| Lorenzi, M; Marinello, E; Pagani, R; Rainis, R; Tabucchi, A | 1 |
| Kopple, JD; Wolfson, M | 1 |
| Abou-Khalil, S; Abou-Khalil, WH; Whitney, PL; Yunis, AA | 1 |
| Jones, WM; Manning, JM | 1 |
| Barthélémy, M; Ben Yaghlane, H; Labia, R; Péduzzi, J | 1 |
| Hama, H; Shimamoto, T; Tsuchiya, T; Tsuda, M | 1 |
| Dunn, KW; Maxfield, FR; McGraw, TE | 1 |
| Bruinvels, J; Fekkes, D; Pepplinkhuizen, L | 1 |
| Flückiger, R; Gallop, PM; Woodtli, T | 1 |
| Anderson, PJ; Ferrarotto, C; Hetenyi, G; Raman, M | 1 |
| Barth, PG; de Groot, CJ; Schutgens, RB; Tada, K; Wijburg, FA | 1 |
| Crechet, JB; De Vendittis, E; Fasano, O; Feger, G; Parmeggiani, A; Vitelli, A; Zahn, R | 1 |
| Chanarin, I; Deacon, R; Lumb, M; Perry, J | 1 |
| Mott, J; Sherman, A; Waziri, R; Wilcox, J | 1 |
| Colebrook, LD; Miller, B; Newman, EB; Walker, C | 1 |
| Keefer, JF; Moraga, DA; Schuster, SM | 1 |
| Bhattacharya, S; Dickhoff, WW; Gorbman, A; Plisetskaya, E | 1 |
| Bishop, SH; Burcham, JM; Ellis, LL; Paynter, KT | 1 |
| Brandt-Rauf, PW; Pincus, MR | 1 |
| Gierlach, P; Hörl, WH; Kluthe, R; Schollmeyer, P | 1 |
| Hobbs, JG; Kaye, PL | 1 |
| Arnheim, N; Clark, R; McCormick, F; Nitecki, D; Wong, G | 1 |
| Lund, P; Williamson, DH | 1 |
| Hansen, S; Perry, TL | 1 |
| Brattström, LE; Hardebo, JE; Hultberg, BL | 1 |
| Kitaoka, S; Komura, H; Yokota, A | 1 |
| Noguchi, T; Takada, Y | 1 |
| Brosnan, JT; Hall, B; Hall, DE; Lowry, M | 1 |
| Kolchanov, NA; Shindyalov, IN | 1 |
| Mircevová, L; Mokrý, Z; Simonová, A | 1 |
| Hess, M; Hilschmann, N | 2 |
| Kikuchi, G; Motokawa, Y | 3 |
| Kikuchi, G; Yoshida, T | 6 |
| Gibson, D; Levanon, M; Smithies, O | 1 |
| Elias, PM; Montague, PM; Ugel, AR | 1 |
| Gerstenbrand, F; Gründig, E; Oberhummer, J; Schedl, R; Simanyi, M; Weiss, J | 1 |
| Bryce, GF | 1 |
| Asghar, SS; Harold, FM; Levin, E | 1 |
| Frisell, WR; Randolph, VM | 1 |
| Katunuma, N; Kobayashi, K; Kuroda, Y; Matsuda, Y | 1 |
| Anke, H; Diekmann, H | 1 |
| Roberts, PJ | 1 |
| Bizri, H; Hajjar, JJ; Khuri, RN | 1 |
| Aprison, MH; Daly, E; McBride, WJ | 1 |
| Colley, L; Fox, FR; Huggins, AK | 1 |
| Kasarian, BA | 1 |
| Kennedy, AJ; Voaden, MJ | 1 |
| Jaton, JC | 1 |
| Bassett, EW; Beiser, SM; Tanenbaum, SW | 1 |
| Paul, I; Wohllebe, W | 1 |
| Feteanu, A; Peeters, G; Verbeke, R | 1 |
| Givol, D; Rüde, E | 1 |
| Knöfel, R; Müller, M; Rapoport, S | 1 |
| Hess, M; Hilschmann, N; Ponstingl, H | 1 |
| Bundgaard, L; Winther, A | 1 |
| Mikhail, MM; Patwardhan, VN; Waslien, CI | 1 |
| Murray, CL; Rabinowitz, JC; Samuel, CE | 1 |
| Chaloupka, J; Krecková, P | 1 |
| Clark, VL; Young, FE | 1 |
| Hubert, JC; Wurtz, B | 1 |
| Cifonelli, JA; Dorfman, A; Varadi, DP | 1 |
| Bella, A; Danishefsky, I | 1 |
| Lloyd, PH; Manley, G; Mullinger, RN | 1 |
| Braun, W; Weiss, C; Zschaler, W | 1 |
| Plapp, R; Strominger, JL | 1 |
| Lee, TY; Onisawa, J | 1 |
| Combepine, G; Cossins, EA; Turian, G | 1 |
| Andersen, AE; Guroff, G; Rowe, VD; Sidbury, JB; Zigler, S | 1 |
| Harrap, KR; Jackson, RC | 1 |
| Byrne, WL; Fallon, HJ; Hackney, EJ | 1 |
| Herbert, E; Smith, CJ | 1 |
| Brown, EG; Silver, AV | 1 |
| Lohmann, W; Momeni, M; Nette, P | 1 |
| Baranova, AM; Bragina, MP; Moroz, AF | 1 |
| Davis, JL; Fallon, HJ; Goyer, RA | 1 |
| Johnston, GA | 1 |
| Barascut, JL; Borel, JP; Desanti, M; Guillaume, G | 1 |
| Curtis, DR; De Groat, WC; Johnston, GA | 1 |
| Kikuchi, G; Kochi, H; Sato, N; Sato, T | 1 |
| Borghetti, AF; Guidotti, GG; Lüneburg, B | 1 |
| Bańkowski, E; Galasiński, W | 1 |
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| Balmer, ML; Bantug, G; Boukhaled, G; Condotta, S; Frezza, C; Friedman, A; Griss, T; Guak, H; Henriques da Costa, S; Hess, C; Johnson, RM; Jones, RG; Krawczyk, CM; Ma, EH; Mainolfi, N; Manfredi, M; Raissi, TC; Richer, MJ; Samborska, B; Suri, V; Tsui, H; Verway, MJ | 1 |
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| Barone, G; Gorska-Ponikowska, M; Kuban-Jankowska, A; Lo Bosco, G; Perricone, U | 1 |
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| Bouzon, M; Delmas, V; Loreau, O; Marlière, P; Perchat, N; Perret, A; Taran, F; Weissenbach, J | 1 |
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| Ansbro, B; Ard, S; Dulin, NO; Guzy, RD; Hamanaka, RB; Meliton, AY; Mutlu, GM; Nigdelioglu, R; O'Leary, E; Rohde, JM; Sun, KA; Tian, Y; Witt, LJ; Woods, PS; Wu, D | 1 |
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| Connolly, BS; de Bie, RM; Faust-Socher, A; Gasca-Salas, C; Ghate, T; Jain, J; Kasten, M; Kausar, F; Kern, DS; Klein, C; Kumar, P; Lang, AE; Marras, C; Mestre, TA; Pont-Sunyer, C; Schüle, B; Slow, EJ; Thomsen, T; Tolosa, E; Visanji, NP; Wadia, PM; Zadikoff, C | 1 |
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93 review(s) available for serine and glycine
| Article | Year |
|---|---|
[Amino acids as transmitters: glycine, taurine and serine].
Topics: Animals; Anura; Cats; Central Nervous System; gamma-Aminobutyric Acid; Glycine; Hypothalamus; Mice; Neurotransmitter Agents; Rats; Serine; Taurine | 1978 |
Aminotransferase activity in brain.
Topics: Alanine Transaminase; Animals; Asparagine; Aspartate Aminotransferases; Brain; Catalysis; Chemical Phenomena; Chemistry; Diet; gamma-Aminobutyric Acid; Glucose; Glutamine; Glycine; Hormones; Humans; Isoenzymes; Ketoglutaric Acids; Ornithine; Rats; Serine; Swine; Transaminases; Tyrosine Transaminase | 1975 |
Inter-tissue nitrogen fluxes.
Topics: Alanine; Amino Acids; Animals; Erythrocytes; Glutamine; Glycine; Humans; Intestine, Small; Liver; Muscles; Nitrogen; Rats; Serine; Wounds and Injuries | 1985 |
[Tissue collagenolytic enzymes].
Topics: Alanine; Animals; Anura; Biodegradation, Environmental; Collagen; Connective Tissue; Glycine; Humans; Hydroxyproline; Microbial Collagenase; Puromycin; Serine; Valine | 1970 |
[Regulation of synthesis of uric acid as the final stage of nitrogen metabolism].
Topics: Animals; Chickens; Glutamate-Ammonia Ligase; Glutamates; Glutaminase; Glutamine; Glycine; Humans; Hypoxanthines; Inosine; Inosine Nucleotides; Liver; Nitrogen; Nucleotidases; Phosphorylase Kinase; Rats; Serine; Uremia; Uric Acid; Xanthine Oxidase; Xanthines | 1972 |
[Physiological pathways of glycine and serine catabolism in vertebrates].
Topics: Animals; Birds; Cattle; Chemical Phenomena; Chemistry; Dogs; Fishes; Gluconeogenesis; Glycine; Glyoxylates; Goats; Guinea Pigs; Humans; Liver; Oxalates; Rabbits; Rats; Serine; Sheep; Snakes; Swine | 1972 |
Dietary factors influencing amino acid degradation.
Topics: Amino Acids; Aminoisobutyric Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginase; Arginine; Chickens; Creatine; Diet; Feces; Glycine; Kidney; Lysine; Nutritional Requirements; Rats; Serine; Urea | 1972 |
[Clinical study of arylamidases].
Topics: Adrenal Glands; Amidohydrolases; Bile; Biliary Tract Diseases; Glycine; Humans; Intestinal Mucosa; Kidney; Leucine; Leucyl Aminopeptidase; Liver; Liver Diseases; Myocardium; Naphthalenes; Pancreas; Pancreatic Diseases; Peptides, Cyclic; Salivary Glands; Serine | 1972 |
The glycine cleavage system: composition, reaction mechanism, and physiological significance.
Topics: Animals; Carbon Radioisotopes; Catalysis; Chemical Phenomena; Chemistry; Chickens; Glycine; Humans; Mitochondria, Liver; Multienzyme Complexes; Organ Specificity; Rats; Serine; Species Specificity; Tetrahydrofolates; Vertebrates | 1973 |
Enzymes in peroxisomes.
Topics: Acyltransferases; Alcohol Oxidoreductases; Carnitine; Chloroplasts; Fatty Acids; Glyceric Acids; Glycerolphosphate Dehydrogenase; Glycine; Glycolates; Glyoxylates; Kidney; L-Lactate Dehydrogenase; Liver; Malate Dehydrogenase; Malates; Microbodies; Organoids; Plant Cells; Plants; Serine | 1973 |
[Dynamic states of amino acid metabolism in mammals (author's transl)].
Topics: Alanine; Amino Acids; Ammonia; Animals; Carbon Radioisotopes; Erythrocytes; Fasting; Glutamine; Glycine; Humans; Liver; Rats; Serine | 1974 |
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Invariant features of globin primary structure and coding of their secondary structure.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Globins; Glycine; Hemoglobins; Histidine; Myoglobin; Proline; Protein Conformation; Serine; Species Specificity; Threonine; Tyrosine | 1974 |
The lack of requirement for glycine in the growing chick.
Topics: Animal Nutritional Physiological Phenomena; Animals; Arginine; Chickens; Dietary Proteins; Glycine; Serine | 1968 |
[Multiplicity and specificity in code recognition of tRNA against specific amino acid].
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography; Cystine; Escherichia coli; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Leucine; Liver; Lysine; Phenylalanine; Rabbits; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Serine; Threonine; Tyrosine; Yeasts | 1969 |
Drugs, toxins and dietary amino acids affecting vitamin B12 or folic acid absorption or utilization.
Topics: Amino Acids; Anemia, Macrocytic; Contraceptives, Oral; Diet; DNA; Ethanol; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Glycine; Homocysteine; Humans; Malabsorption Syndromes; Methionine; Pharmacology; Serine; Toxins, Biological; Vitamin B 12 | 1970 |
The plasma amino acid ratio as an indicator of the protein nutrition status: a review of recent work.
Topics: Amino Acids; Animals; Child; Child Nutritional Physiological Phenomena; Child, Preschool; Chromatography, Paper; Dietary Proteins; Glutamine; Glycine; Humans; Infant; Isoleucine; Kwashiorkor; Leucine; Mathematics; Methionine; Nutrition Disorders; Protein Deficiency; Rats; Serine; Taurine; Valine | 1970 |
Selective cleavage and modification of peptides and proteins.
Topics: Alanine; Aspartic Acid; Chemical Phenomena; Chemistry; Chymotrypsin; Cysteine; Glutamates; Glycine; Hydrogen-Ion Concentration; Methionine; Muramidase; Oxidation-Reduction; Peptides; Phenylalanine; Proline; Proteins; Pyrrolidines; Ribonucleases; Serine; Succinates; Threonine; Tryptophan | 1970 |
Biosynthesis of uric acid in the tunicate, Molgula manhattensis, with a general scheme for the function of stored purines in animals.
Topics: Adenine; Allopurinol; Animals; Carbon Isotopes; Carbonates; Chordata, Nonvertebrate; Formates; Glycine; Hypoxanthines; Purines; Serine; Tritium; Uric Acid; Xanthine Oxidase | 1970 |
Aggravation or initiation of megaloblastosis by amino acids in the diet.
Topics: Amino Acids; Anemia, Pernicious; Cell Nucleus; Diet; DNA; Erythrocytes; Folic Acid; Folic Acid Deficiency; Glycine; Hematologic Diseases; Homocystine; Humans; Methionine; Polycythemia; Pyridoxine; Serine; Tetrahydrofolate Dehydrogenase; Thymine; Vitamin B 12; Vitamin B 12 Deficiency | 1970 |
Metabolism of single carbon compounds.
Topics: Alcohol Oxidoreductases; Bacteria; Carboxy-Lyases; Glycine; Hexosephosphates; Methane; Methanol; Microscopy, Electron; Oxidation-Reduction; Oxidoreductases; Oxygenases; Pseudomonas; Serine; Transferases | 1970 |
Transport of amino acids and peptides in the gut and the kidney.
Topics: Adult; Alanine; Amino Acids; Animals; Biological Transport, Active; Digestive System; Glycine; Hartnup Disease; Histidine; Humans; Hydrolysis; Intestinal Absorption; Kidney; Kidney Tubules; Leucine; Lysine; Methionine; Peptides; Phenylalanine; Proteins; Rats; Serine; Threonine; Tryptophan; Valine | 1971 |
Amino acid nutrition of the chick--essentiality of proline and glycine biosynthesis.
Topics: Amination; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Chickens; Dealkylation; Dietary Proteins; Glycine; Glyoxylates; Growth; Liver; Male; Nutritional Requirements; Proline; Rats; Sarcosine; Serine; Species Specificity; Time Factors | 1971 |
Stereochemical aspects of pyridoxal phosphate catalysis.
Topics: 5-Aminolevulinate Synthetase; Alanine Transaminase; Allosteric Regulation; Amino Acids; Aspartic Acid; Binding Sites; Carboxy-Lyases; Catalysis; Cystathionine; Glycine; Homoserine; Kinetics; Lyases; Models, Biological; Molecular Conformation; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Schiff Bases; Serine; Structure-Activity Relationship; Threonine; Transaminases; Transferases | 1971 |
Adverse effects of excessive consumption of amino acids.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Brain; Cattle; Diet; Disease Models, Animal; Ethionine; Fenclonine; Glycine; Growth Disorders; Histidine; Humans; Methionine; Nerve Tissue Proteins; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pneumonia, Atypical Interstitial, of Cattle; Serine; Stereoisomerism; Sulfhydryl Compounds; Tissue Distribution; Tryptophan; Tyrosine; Vitamin A | 1984 |
Nonketotic hyperglycinemia: clinical, biochemical, and therapeutic considerations.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Benzoates; Biological Transport; Brain; Carboxy-Lyases; Dietary Proteins; Glycine; Humans; Hydrogen; Methylmalonyl-CoA Decarboxylase; Mice; Proteins; Rats; Receptors, Cell Surface; Receptors, Glycine; Salicylates; Serine; Strychnine | 1983 |
[Structure and function of luliberin (author's transl)].
Topics: Chemical Phenomena; Chemistry; Follicle Stimulating Hormone; Glycine; Gonadotropin-Releasing Hormone; Histidine; Humans; Leucine; Luteinizing Hormone; Molecular Conformation; Pyrrolidonecarboxylic Acid; Serine; Tryptophan; Tyrosine | 1980 |
Advances in amino acid metabolism in mammals.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acid Oxidoreductases; Amino Acids; Animals; Biological Transport; Dietary Proteins; Glutamates; Glycine; Humans; Liver; Mitochondria; Organ Specificity; Ornithine; Purine Nucleotides; Serine; Threonine; Transaminases | 1981 |
A survey of inborn errors of amino acid metabolism and transport in man.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Amino Acids, Branched-Chain; Biological Transport; Cystinosis; Female; Glutathione; Glycine; Homocystinuria; Humans; Hydroxyproline; Infant; Infant, Newborn; Lysine; Maple Syrup Urine Disease; Phenylalanine; Proline; Serine; Tyrosine; Urea; Valine | 1981 |
The co-agonist concept: is the NMDA-associated glycine receptor saturated in vivo?
Topics: Animals; Cerebellum; Glycine; Hippocampus; Humans; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine | 1995 |
Mutagenesis studies of the cardiac Na(+)-Ca2+ exchanger.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Calcium; Carrier Proteins; Dogs; Glutamic Acid; Glycine; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardium; Serine; Sodium; Sodium-Calcium Exchanger; Structure-Activity Relationship; Threonine | 1996 |
Deficient expression of the small proteoglycan decorin in a case of severe/lethal osteogenesis imperfecta.
Topics: Blotting, Northern; Blotting, Western; Cells, Cultured; Decorin; Extracellular Matrix Proteins; Female; Fibroblasts; Genes, Lethal; Genetic Carrier Screening; Glycine; Humans; Infant, Newborn; Male; Osteogenesis Imperfecta; Phenotype; Point Mutation; Proteoglycans; RNA, Messenger; Serine; Skin | 1996 |
[Glycine therapy of schizophrenia; its rationale and a review of clinical trials].
Topics: Acetamides; Alanine; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Cycloserine; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Humans; Prodrugs; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine | 1998 |
Continuing education in neurometabolic disorders--serine deficiency disorders.
Topics: Adolescent; Amino Acids; Child; Deficiency Diseases; Female; Glycine; Humans; Ichthyosis; Male; Metabolism, Inborn Errors; Microcephaly; Serine; Spasms, Infantile; Williams Syndrome | 1999 |
[Endogenous D-serine in mammalian brains].
Topics: Animals; Brain; Glutamic Acid; Glycine; Humans; Racemases and Epimerases; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Spinocerebellar Degenerations; Synaptic Transmission | 2000 |
Treatment of negative and cognitive symptoms.
Topics: Antimetabolites; Antipsychotic Agents; Cognition Disorders; Cycloserine; Glycine; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Serine; Treatment Outcome | 1999 |
[Biosynthesis of nonessential amino acids and the urea-cycle in silkworms].
Topics: Alanine; Ammonia; Animals; Bombyx; Fibroins; Glycine; Isotope Labeling; Magnetic Resonance Spectroscopy; Serine; Urea | 2001 |
Anticoagulation: the present and future.
Topics: Administration, Oral; Amino Acid Chloromethyl Ketones; Anticoagulants; Arginine; Azetidines; Benzylamines; Binding Sites; Biological Availability; Blood Coagulation; Comorbidity; Coumarins; Drug Design; Embolism; Female; Forecasting; Glycine; Guanidines; Heart Diseases; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Hirudin Therapy; Humans; Neoplasms; Pipecolic Acids; Pregnancy; Pregnancy Complications, Hematologic; Prodrugs; Safety; Serine; Stroke; Sulfonamides; Thrombin; Thrombophilia; Thrombosis | 2001 |
Steps towards an integrated view of nitrogen metabolism.
Topics: Amino Acid Oxidoreductases; Amino Acids; Asparagine; Cysteine; Gene Expression Regulation, Plant; Glutamate Dehydrogenase; Glutamine; Glycine; Ketoglutaric Acids; Malates; Nicotiana; Nitrate Reductase; Nitrate Reductases; Nitrates; Nitrogen; Oxidation-Reduction; Quaternary Ammonium Compounds; Serine; Signal Transduction | 2002 |
Pharmacogenetics of tardive dyskinesia: combined analysis of 780 patients supports association with dopamine D3 receptor gene Ser9Gly polymorphism.
Topics: Adult; Aged; Analysis of Variance; Chi-Square Distribution; Confidence Intervals; Dyskinesia, Drug-Induced; Exons; Female; Genetic Predisposition to Disease; Glycine; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Pharmacogenetics; Polymorphism, Genetic; Receptors, Dopamine D2; Receptors, Dopamine D3; Serine | 2002 |
Genetic disorders of gamma-aminobutyric acid, glycine, and serine as causes of epilepsy.
Topics: Amino Acid Metabolism, Inborn Errors; Epilepsy; Female; gamma-Aminobutyric Acid; Glycine; Humans; Infant, Newborn; Serine | 2002 |
Dopamine D3 receptor gene Ser9Gly variant and schizophrenia: association study and meta-analysis.
Topics: Amino Acid Substitution; Case-Control Studies; Genetic Variation; Glycine; Homozygote; Humans; Receptors, Dopamine D2; Receptors, Dopamine D3; Reference Values; Schizophrenia; Serine; Sweden | 2003 |
Genetic manipulation of glycine decarboxylation.
Topics: Amino Acid Oxidoreductases; Arabidopsis; Glycine; Glycine Dehydrogenase (Decarboxylating); Glycine Hydroxymethyltransferase; Hordeum; Mutation; Photosynthetic Reaction Center Complex Proteins; Serine | 2003 |
AMINO ACID METABOLISM.
Topics: Amino Acid Oxidoreductases; Amino Acids; Carboxy-Lyases; Glutamates; Glycine; Hydroxyproline; Lysine; Peroxidases; Phenylalanine; Proline; Proteins; Pyridoxal Phosphate; Research; Serine; Threonine; Transaminases; Tryptophan; Tyrosine; Urea | 1963 |
The N-methyl D-aspartate receptor glycine site and D-serine metabolism: an evolutionary perspective.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Animals; Binding Sites; Brain; Glycine; Molecular Sequence Data; Phylogeny; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Sequence Alignment; Serine; Synaptic Transmission | 2004 |
N-Methyl-D-aspartate receptors as a target for improved antipsychotic agents: novel insights and clinical perspectives.
Topics: Animals; Antipsychotic Agents; Glycine; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine | 2005 |
[S20G mutation of amylin gene--amyloid diabetes due to S20G amylin gene mutation].
Topics: Amino Acid Sequence; Amino Acid Substitution; Amyloid; Animals; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Glycine; Humans; Islet Amyloid Polypeptide; Islets of Langerhans; Molecular Sequence Data; Mutation, Missense; Serine | 2005 |
[HNF-1alpha G319S mutation in Oji-Cree type 2 diabetes].
Topics: Amino Acid Substitution; Canada; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Genetic Predisposition to Disease; Glycine; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Humans; Indians, North American; Life Style; Mutation, Missense; Nuclear Proteins; Ontario; Prognosis; Serine; Transcription Factors | 2005 |
Serine hydroxymethyltransferase revisited.
Topics: Glycine; Glycine Hydroxymethyltransferase; Hydrolysis; Serine; Stereoisomerism | 2005 |
Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and related phenotypes.
Topics: Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Fasting; Glycine; Heat-Shock Proteins; Humans; Insulin; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phenotype; Polymorphism, Genetic; Serine; Transcription Factors | 2006 |
The role of group I metabotropic glutamate receptors in schizophrenia.
Topics: Animals; Antipsychotic Agents; Brain; Disease Models, Animal; Glycine; Humans; Mice; Mice, Knockout; Models, Biological; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine | 2007 |
[Update on the animal models of schizophrenia].
Topics: Animals; Behavior, Animal; Brain; Disease Models, Animal; Drug Design; Excitatory Amino Acid Antagonists; Glycine; Humans; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine | 2006 |
LRRK2 low-penetrance mutations (Gly2019Ser) and risk alleles (Gly2385Arg)-linking familial and sporadic Parkinson's disease.
Topics: Alleles; Amino Acid Substitution; Asia; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Parkinson Disease; Penetrance; Protein Serine-Threonine Kinases; Risk; Serine | 2007 |
Novel therapeutics for schizophrenia: targeting glycine modulation of NMDA glutamate receptors.
Topics: Amino Acid Transport Systems; Antipsychotic Agents; Glycine; Glycine Agents; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine | 2007 |
Potentiation of the NMDA receptor in the treatment of schizophrenia: focused on the glycine site.
Topics: Acetamides; Alanine; Antipsychotic Agents; Clozapine; Cognition; Cycloserine; Dopamine Agents; Drug Synergism; Drug Therapy, Combination; Glycine; Glycine Agents; Glycine Plasma Membrane Transport Proteins; Humans; Monoamine Oxidase Inhibitors; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Sarcosine; Schizophrenia; Schizophrenic Psychology; Serine | 2008 |
NMDA receptor regulation by D-serine: new findings and perspectives.
Topics: Animals; Cerebral Cortex; Glycine; Humans; Neurons; Neurotransmitter Agents; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Serine | 2007 |
[Metabolism and functions of brain D-serine in mammals: relevance to neuropsychiatric disorders].
Topics: Animals; Brain; Drug Design; Glycine; Humans; Isomerism; Mental Disorders; Nervous System Diseases; Neuroglia; Neurons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Schizophrenia; Serine | 2008 |
Allosteric modulation of NMDA receptor via elevation of brain glycine and D-serine: the therapeutic potentials for schizophrenia.
Topics: Allosteric Regulation; Animals; Glycine; Glycine Plasma Membrane Transport Proteins; Humans; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine | 2008 |
Flexible structures and ligand interactions of tandem repeats consisting of proline, glycine, asparagine, serine, and/or threonine rich oligopeptides in proteins.
Topics: Animals; Asparagine; Glycine; Humans; Ligands; Oligopeptides; Proline; Protein Conformation; Proteins; Serine; Tandem Repeat Sequences; Threonine | 2008 |
Dopamine receptor D3 (DRD3) genotype and allelic variants and risk for essential tremor.
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Case-Control Studies; DNA Mutational Analysis; Essential Tremor; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glycine; Humans; Male; Middle Aged; Odds Ratio; Receptors, Dopamine D3; Serine; Spain; Young Adult | 2009 |
LRRK2 G2019S in the North African population: a review.
Topics: Africa, Northern; Genetic Predisposition to Disease; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Parkinson Disease; Population Groups; Protein Serine-Threonine Kinases; Serine | 2010 |
Aberrant control of motoneuronal excitability in amyotrophic lateral sclerosis: excitatory glutamate/D-serine vs. inhibitory glycine/gamma-aminobutanoic acid (GABA).
Topics: Amyotrophic Lateral Sclerosis; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Motor Neurons; Neurotransmitter Agents; Receptors, Glutamate; Serine | 2010 |
[Analysis of mouse strain-dependent prepulse inhibition points to a role for Shmt1 (SHMT1) in mice and in schizophrenia].
Topics: Animals; Glycine; Glycine Hydroxymethyltransferase; Humans; Mice; Mice, Inbred Strains; Neural Inhibition; Quantitative Trait Loci; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine | 2010 |
[Development of a novel pharmacotherapy targeted at the N-methyl-D-aspartate receptor-D-serine system for schizophrenia].
Topics: Animals; Clinical Trials as Topic; Drug Design; Glycine; Humans; Molecular Targeted Therapy; Phencyclidine; Psychotropic Drugs; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine | 2010 |
Amperometric microbiosensor as an alternative tool for investigation of D-serine in brain.
Topics: Animals; Biosensing Techniques; Brain; Brain Chemistry; D-Amino-Acid Oxidase; Electrodes, Implanted; Extracellular Fluid; Glycine; Kinetics; Limit of Detection; Neurons; Phenylenediamines; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism | 2012 |
D-serine: physiology and pathology.
Topics: Animals; Astrocytes; Glycine; Hippocampus; Humans; Long-Term Potentiation; Models, Animal; Neurons; Neurotoxicity Syndromes; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Synaptic Transmission | 2013 |
NMDA receptor activation: two targets for two co-agonists.
Topics: Amino Acid Transport System ASC; Animals; Glycine; Humans; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Serine; Synapses | 2013 |
Serine, glycine and one-carbon units: cancer metabolism in full circle.
Topics: Epigenesis, Genetic; Glycine; Humans; Methylation; Neoplasms; Oxidation-Reduction; Serine | 2013 |
Unmet needs in the treatment of schizophrenia: new targets to help different symptom domains.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Antipsychotic Agents; Cognition Disorders; Glycine; Humans; Molecular Targeted Therapy; Receptors, Glutamate; Schizophrenia; Serine | 2014 |
Serine and glycine metabolism in cancer.
Topics: Cell Proliferation; Glycine; Humans; Metabolic Networks and Pathways; Neoplasms; Serine | 2014 |
Formylglycine, a post-translationally generated residue with unique catalytic capabilities and biotechnology applications.
Topics: Alanine; Animals; Binding Sites; Biotechnology; Catalysis; Catalytic Domain; Cysteine; Glycine; Humans; Models, Molecular; Protein Processing, Post-Translational; Serine; Sulfotransferases | 2015 |
The NMDA receptor 'glycine modulatory site' in schizophrenia: D-serine, glycine, and beyond.
Topics: Animals; Antipsychotic Agents; Cognition Disorders; Dopamine; Glycine; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Synapses | 2015 |
Pharmacological treatment of negative symptoms in schizophrenia.
Topics: Antidepressive Agents; Antipsychotic Agents; Excitatory Amino Acid Agents; Glycine; Glycine Agents; Humans; Schizophrenia; Schizophrenic Psychology; Serine; Treatment Outcome | 2015 |
Meta-analysis of the influence of dietary glycine and serine, with consideration of methionine and cysteine, on growth and feed conversion of broilers.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Cysteine; Diet; Glycine; Methionine; Serine | 2015 |
Folate-Dependent Purine Nucleotide Biosynthesis in Humans.
Topics: Carbon; Circadian Rhythm; Folic Acid; Formates; Glycine; Humans; Leucovorin; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Phosphoribosylglycinamide Formyltransferase; Purine Nucleotides; Serine; Uric Acid | 2015 |
Nonessential amino acid metabolism in breast cancer.
Topics: Animals; Arginine; Breast Neoplasms; Cysteine; Diet Therapy; Female; Food Deprivation; Glutamic Acid; Glutamine; Glycine; Humans; Metabolic Networks and Pathways; Proline; Serine | 2016 |
Give it or take it: the flux of one-carbon in cancer cells.
Topics: Animals; Carbon; Carbon Cycle; Cell Compartmentation; Cytosol; Embryonic Development; Glycine; Humans; Metabolic Networks and Pathways; Methylation; Mitochondria; Models, Biological; Neoplasms; Serine | 2016 |
Body fluid levels of neuroactive amino acids in autism spectrum disorders: a review of the literature.
Topics: Amino Acids; Autism Spectrum Disorder; Body Fluids; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; Humans; Serine; Taurine; Tryptophan | 2017 |
Linking Metabolic Disease With the PGC-1α Gly482Ser Polymorphism.
Topics: Amino Acid Substitution; Diabetes Mellitus, Type 2; Genetic Linkage; Genetic Predisposition to Disease; Glycine; Humans; Insulin Resistance; Metabolic Diseases; Mutation, Missense; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Polymorphism, Single Nucleotide; Serine | 2018 |
In Vitro Modeling of Leucine-Rich Repeat Kinase 2 G2019S-Mediated Parkinson's Disease Pathology.
Topics: Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mitochondria; Mutation; Parkinson Disease; Precision Medicine; Reactive Oxygen Species; Serine; Translational Research, Biomedical | 2018 |
Inborn Errors of Metabolism with Seizures: Defects of Glycine and Serine Metabolism and Cofactor-Related Disorders.
Topics: Child; Child, Preschool; Coenzymes; Diagnosis, Differential; Epilepsy; Glycine; Humans; Infant; Infant, Newborn; Metabolism, Inborn Errors; Serine | 2018 |
Glycine transporter inhibitors: A new avenue for managing neuropathic pain.
Topics: Animals; Glycine; Glycine Plasma Membrane Transport Proteins; Humans; Hyperalgesia; Neuralgia; Neuroglia; Neurons; Phenols; Piperidines; Receptors, N-Methyl-D-Aspartate; Serine; Spinal Cord Dorsal Horn; Synapses; Synaptic Transmission | 2019 |
The complexity of the serine glycine one-carbon pathway in cancer.
Topics: Animals; Carbon; Glycine; Humans; Metabolic Networks and Pathways; Neoplasms; Serine | 2020 |
Reprogramming of serine, glycine and one-carbon metabolism in cancer.
Topics: Animals; Carbon; Cellular Reprogramming; Glycine; Humans; Metabolic Networks and Pathways; Methionine; Mitochondria; Neoplasms; Protein Processing, Post-Translational; Serine; Transcription Factors | 2020 |
More than just protein building blocks: how amino acids and related metabolic pathways fuel macrophage polarization.
Topics: Arginase; Arginine; Cell Differentiation; Citric Acid Cycle; Gene Expression Regulation; Glutamine; Glycine; Humans; Immunity, Innate; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Mitochondria; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Phosphorylation; Serine | 2021 |
Serine, glycine and one‑carbon metabolism in cancer (Review).
Topics: Animals; Antineoplastic Agents; Carbon; Carcinogenesis; Disease Models, Animal; Glycine; Humans; Metabolic Networks and Pathways; Methylation; Mice; Neoplasms; Oxidation-Reduction; Serine; Tumor Microenvironment; Warburg Effect, Oncologic | 2021 |
The ins and outs of serine and glycine metabolism in cancer.
Topics: Animals; Glycine; Humans; Neoplasms; Serine | 2021 |
Glycine agonism in ionotropic glutamate receptors.
Topics: Animals; Binding Sites; Glutamic Acid; Glycine; Humans; Ligands; Mice; Receptors, Ionotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission; Xenopus laevis | 2021 |
Phosphatases of regenerating liver are key regulators of metabolism in cancer cells - role of Serine/Glycine metabolism.
Topics: Glycine; Humans; Liver; Neoplasms; Protein Tyrosine Phosphatases; Serine | 2022 |
Current status of cancer starvation therapy.
Topics: Amino Acids; Angiogenesis Inhibitors; Glycine; Humans; Integrins; Neoplasms; Serine | 2022 |
Target enzymes in serine-glycine-one-carbon metabolic pathway for cancer therapy.
Topics: Carbon; Carcinogenesis; Glycine; Humans; Metabolic Networks and Pathways; Neoplasms; Serine | 2023 |
Role of Impaired Glycolysis in Perturbations of Amino Acid Metabolism in Diabetes Mellitus.
Topics: Amino Acids; Amino Acids, Branched-Chain; Diabetes Mellitus, Type 2; Glycine; Glycolysis; Humans; Pyruvic Acid; Serine | 2023 |
Sources and Sinks of Serine in Nutrition, Health, and Disease.
Topics: Amino Acids; Carbon; Glycine; Humans; Nutritional Status; Serine | 2023 |
24 trial(s) available for serine and glycine
| Article | Year |
|---|---|
[The significance of nonessential amino acids for the human nitrogen metabolism during parenteral feeding].
Topics: Adult; Aged; Alanine; Amino Acids; Citrulline; Cystine; Diet; Female; Glycine; Humans; Male; Middle Aged; Nitrogen; Parenteral Nutrition; Proline; Serine; Taurine; Tyrosine | 1968 |
Comparison of serine and hippurate as precursor equivalents during infusion of [15N]glycine for measurement of fractional synthetic rates of apolipoprotein B of very-low-density lipoprotein.
Topics: Adult; Apolipoproteins B; Gas Chromatography-Mass Spectrometry; Glycine; Hippurates; Humans; Lipoproteins, VLDL; Male; Nitrogen Isotopes; Serine; Time Factors | 1995 |
Polymorphism of the gene encoding a human minimal potassium ion channel (minK).
Topics: Alleles; Animals; Base Sequence; Chromosomes, Human, Pair 11; Codon; DNA Primers; Genetic Carrier Screening; Genetic Linkage; Glycine; Hominidae; Humans; Long QT Syndrome; Molecular Sequence Data; Polymerase Chain Reaction; Polymorphism, Genetic; Potassium Channels; Potassium Channels, Voltage-Gated; Serine | 1994 |
Serum levels of excitatory amino acids, serine, glycine, histidine, threonine, taurine, alanine and arginine in treatment-resistant depression: modulation by treatment with antidepressants and prediction of clinical responsivity.
Topics: Adult; Aged; Alanine; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arginine; Asparagine; Aspartic Acid; Depressive Disorder, Major; Drug Resistance; Drug Therapy, Combination; Excitatory Amino Acids; Female; Fluoxetine; Glycine; Histidine; Humans; Male; Middle Aged; Personality Inventory; Pindolol; Prognosis; Selective Serotonin Reuptake Inhibitors; Serine; Taurine; Threonine; Trazodone; Treatment Outcome | 1998 |
D-serine added to clozapine for the treatment of schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Glycine; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine | 1999 |
IV glycine and oral D-cycloserine effects on plasma and CSF amino acids in healthy humans.
Topics: Acoustic Stimulation; Administration, Oral; Adult; Amino Acids; Antimetabolites; Biological Availability; Cycloserine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glycine; Humans; Injections, Intravenous; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Serine | 2000 |
Plasma glycine and serine levels in schizophrenia compared to normal controls and major depression: relation to negative symptoms.
Topics: Adult; Chromatography, High Pressure Liquid; Depressive Disorder, Major; Female; Glycine; Humans; Male; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology; Serine | 2004 |
High-dose glycine added to olanzapine and risperidone for the treatment of schizophrenia.
Topics: Adult; Antipsychotic Agents; Behavioral Symptoms; Benzodiazepines; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Glycine; Humans; Male; Middle Aged; Multivariate Analysis; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Serine; Time Factors; Treatment Outcome | 2004 |
Dopamine D3 receptor Ser9Gly polymorphism and risperidone response.
Topics: Adult; Amino Acid Substitution; Antipsychotic Agents; China; DNA; Dose-Response Relationship, Drug; Female; Genotype; Glycine; Humans; Male; Polymorphism, Genetic; Psychiatric Status Rating Scales; Receptors, Dopamine D2; Receptors, Dopamine D3; Risperidone; Schizophrenia; Serine; Social Behavior | 2005 |
Prediction of the ability of clozapine to treat negative symptoms from plasma glycine and serine levels in schizophrenia.
Topics: Adult; Antipsychotic Agents; Chromatography, High Pressure Liquid; Clozapine; Female; Glycine; Humans; Male; Middle Aged; Predictive Value of Tests; Psychiatric Status Rating Scales; Regression Analysis; Schizophrenia; Schizophrenic Psychology; Serine | 2005 |
Subthalamic nucleus stimulation is efficacious in patients with Parkinsonism and LRRK2 mutations.
Topics: Adult; Aged; Deep Brain Stimulation; Female; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinsonian Disorders; Protein Serine-Threonine Kinases; Retrospective Studies; Serine; Subthalamic Nucleus; Threonine | 2007 |
Cerebral metabolic effects of intravenous glycine in healthy human subjects.
Topics: Adult; Antipsychotic Agents; Behavior; Brain; Brain Mapping; Cluster Analysis; Cross-Over Studies; Double-Blind Method; Female; Fluorodeoxyglucose F18; Glycine; Humans; Infusions, Intravenous; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Positron-Emission Tomography; Radiopharmaceuticals; Reference Values; Serine | 2006 |
Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma.
Topics: Adenoma; Aged; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Case-Control Studies; Colonic Neoplasms; Female; Genetic Variation; Genotype; Glutamic Acid; Glycine; Haplotypes; Humans; Ibuprofen; Leucine; Lysine; Male; Methionine; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Racemases and Epimerases; Rectal Neoplasms; Serine; Valine | 2007 |
Could HTR2A T102C and DRD3 Ser9Gly predict clinical improvement in patients with acutely exacerbated schizophrenia? Results from treatment responses to risperidone in a naturalistic setting.
Topics: Adult; Antipsychotic Agents; Female; Glycine; Humans; Male; Pharmacogenetics; Polymorphism, Genetic; Psychiatric Status Rating Scales; Receptors, Dopamine D3; Receptors, Serotonin, 5-HT2; Risperidone; Schizophrenia; Serine | 2008 |
Cerebrospinal fluid D-serine and glycine concentrations are unaltered and unaffected by olanzapine therapy in male schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Glycine; Humans; Male; Middle Aged; Olanzapine; Schizophrenia; Serine | 2008 |
Changes in plasma glycine, L-serine, and D-serine levels in patients with schizophrenia as their clinical symptoms improve: results from the Juntendo University Schizophrenia Projects (JUSP).
Topics: Adolescent; Adult; Antipsychotic Agents; Case-Control Studies; Chi-Square Distribution; Chromatography, High Pressure Liquid; Female; Glycine; Hospitals, University; Humans; Male; Middle Aged; Schizophrenia; Serine; Time Factors; Young Adult | 2008 |
Effects of the DRD3 Ser9Gly polymorphism on aripiprazole efficacy in schizophrenic patients as modified by clinical factors.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Aripiprazole; Female; Genotype; Glycine; Humans; Male; Middle Aged; Pharmacogenetics; Piperazines; Polymorphism, Restriction Fragment Length; Psychiatric Status Rating Scales; Quinolones; Receptors, Dopamine D3; Retrospective Studies; Schizophrenia; Serine; Time Factors; Treatment Outcome | 2009 |
Commercially available amino acid supplementation of low-protein diets for broiler chickens with different ratios of digestible glycine+serine:lysine.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Dietary Proteins; Dietary Supplements; Glycine; Lysine; Male; Serine | 2012 |
Glycine/Serine polymorphism at position 38 influences KCNE1 subunit's modulatory actions on rapid and slow delayed rectifier K+ currents.
Topics: Amino Acid Substitution; Female; Glycine; HEK293 Cells; Humans; Ion Transport; Long QT Syndrome; Male; Polymorphism, Genetic; Potassium; Potassium Channels, Voltage-Gated; Serine | 2014 |
Behavioral and cognitive effects of the N-methyl-D-aspartate receptor co-agonist D-serine in healthy humans: initial findings.
Topics: Adult; Affect; Anxiety; Cognition; Cross-Over Studies; Female; Glutamic Acid; Glycine; Humans; Male; Neuropsychological Tests; Receptors, N-Methyl-D-Aspartate; Serine; Treatment Outcome; Verbal Learning; Young Adult | 2015 |
Methylenetetrahydrofolate Dehydrogenase 1 Polymorphisms Modify the Associations of Plasma Glycine and Serine With Risk of Acute Myocardial Infarction in Patients With Stable Angina Pectoris in WENBIT (Western Norway B Vitamin Intervention Trial).
Topics: Aged; Angina, Stable; Coronary Angiography; Female; Gene Frequency; Genetic Predisposition to Disease; Glycine; Heterozygote; Homozygote; Humans; Linear Models; Logistic Models; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Minor Histocompatibility Antigens; Multivariate Analysis; Myocardial Infarction; Norway; Phenotype; Polymorphism, Genetic; Prognosis; Proportional Hazards Models; Risk Assessment; Risk Factors; Serine; Time Factors | 2016 |
Association between increased serum d-serine and cognitive gains induced by intensive cognitive training in schizophrenia.
Topics: Adult; Cognitive Dysfunction; Cognitive Remediation; Female; Glycine; Humans; Male; Middle Aged; Neuronal Plasticity; Outcome Assessment, Health Care; Schizophrenia; Serine; Verbal Learning; Young Adult | 2019 |
The effect of supplementing glycine and serine to a low crude protein diet on growth and skin collagen abundance of nursery pigs1.
Topics: Animal Feed; Animals; Body Composition; Collagen; Diet; Diet, Protein-Restricted; Dietary Supplements; Glycine; Glycine max; Male; Serine; Skin; Swine | 2020 |
Concentrations of vitamin B12 and folate in maternal serum and fetal fluids, metabolite interrelationships, and hepatic transcript abundance of key folate and methionine cycle genes: the impacts of maternal nutrition during the first 50 d of gestation.
Topics: Animals; Carbon; Cattle; Diet; Female; Folic Acid; Glycine; Liver; Methionine; Pregnancy; Racemethionine; Serine; Vitamin B 12 | 2023 |
2315 other study(ies) available for serine and glycine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
A green fluorescent chemosensor for amino acids provides a versatile high-throughput screening (HTS) assay for proteases.
Topics: Amino Acids; Copper; Drug Evaluation, Preclinical; Endopeptidases; Fluoresceins; Fluorescence; Kinetics; Ligands; Molecular Probes | 2003 |
Hydroxamic acids as a novel family of serine racemase inhibitors: mechanistic analysis reveals different modes of interaction with the pyridoxal-5'-phosphate cofactor.
Topics: Animals; Asparagine; Binding, Competitive; Enzyme Inhibitors; Hydroxamic Acids; Mice; Oximes; Pyridoxal Phosphate; Racemases and Epimerases; Structure-Activity Relationship | 2009 |
Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).
Topics: Amino Acid Transport Systems; Caco-2 Cells; Endocytosis; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Substrate Specificity; Symporters | 2011 |
Effect of taurine on ethanol-induced sleeping time in mice.
Topics: Alanine; Aminobutyrates; Animals; Arginine; Cysteic Acid; Dose-Response Relationship, Drug; Ethanol; Glycine; Injections, Intraperitoneal; Isethionic Acid; Lysine; Male; Mice; Reaction Time; Serine; Sleep; Taurine | 1976 |
Drug-induced parkinsonism in the rat- a model for biochemical investigation of the parkinson-syndrome. III. The incorporation of D-glucose-14C(U) in amino acids of brain and liver from rats pretreated with reserpine or with phenothiazines.
Topics: Amino Acids; Animals; Antipsychotic Agents; Brain; Glucose; Glutamates; Glutamine; Glycine; Liver; Male; Parkinson Disease, Secondary; Phenothiazines; Rats; Reserpine; Serine | 1976 |
Conversion of the active-site cysteine residue of papain into a dehydro-serine, a serine and a glycine residue.
Topics: Acetophenones; Binding Sites; Cysteine; Glycine; Hydrogen-Ion Concentration; Papain; Photolysis; Serine; Spectrometry, Fluorescence | 1978 |
Substrate-specificity of "high-affinity", Na+ -independent binding of beta-alanine to cerebral synaptosomal-mitochondrial fractions.
Topics: Alanine; Animals; beta-Alanine; Bicuculline; Binding, Competitive; Brain; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Leucine; Male; Mitochondria; Neurotransmitter Agents; Rats; Serine; Strychnine; Synaptosomes; Taurine; Valine | 1978 |
Production of L-serine by Sarcina albida.
Topics: Bacteria; Culture Media; Glycine; Glycine Hydroxymethyltransferase; Hydrogen-Ion Concentration; L-Serine Dehydratase; Sarcina; Serine; Species Specificity; Stereoisomerism; Temperature | 1979 |
[Free amino acids of hemolymph of marine isopods, Sphaeroma hookers Sphaeroma serratum (Flabellifera) and Idotea balthica (Valvifera)].
Topics: Amino Acids; Animals; Crustacea; Glycine; Hemolymph; Reference Values; Serine; Species Specificity; Taurine | 1976 |
[Clinical study on the concentration of free amino acids in plasma and urine during postaggression metabolism. I].
Topics: Amino Acids, Essential; Glycine; Humans; Parenteral Nutrition; Postoperative Care; Serine; Surgical Procedures, Operative; Water-Electrolyte Balance | 1978 |
Non-ketotic hyperglycinaemia in a family with an unusual phenotype.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Female; Glycine; Humans; Male; Phenotype; Serine | 1978 |
The formation of serine from glycine and formaldehyde by cell free extracts of Clostridium acidi-urici.
Topics: Cell-Free System; Clostridium; Edetic Acid; Formaldehyde; Glycine; Isomerism; Pyruvates; Serine | 1979 |
Pools and protein synthesis: studies with the D- and L-isomers of leucine.
Topics: Cycloheximide; Diffusion; Glycine; HeLa Cells; Humans; Isomerism; Kinetics; Leucine; Protein Biosynthesis; Serine; Valine | 1979 |
The effects of sodium arsenate on the free amino acid levels in erythrocytes and plasma in rats.
Topics: Amino Acids; Aminobutyrates; Animals; Arsenates; Arsenic; Aspartic Acid; Betaine; Circadian Rhythm; Erythrocytes; Female; Glutamine; Glycine; Hydroxyproline; Isoleucine; Leucine; Male; Ornithine; Proline; Rats; Serine; Sex Factors; Starvation; Taurine; Valine | 1979 |
Studies on the metabolism of beta-hydroxy- aspartic acid.
Topics: Animals; Aspartic Acid; Dogs; Glutamates; Glycine; Guinea Pigs; Humans; Liver; Rabbits; Rats; Serine; Species Specificity; Swine; Thiamine | 1975 |
Taurine and isoproterenol toxicity.
Topics: Animals; Cardiomegaly; Glycine; Isoproterenol; Male; Myocardium; Organ Size; Rats; Serine; Taurine; Time Factors | 1976 |
One-carbon metabolism in Neurospora crassa wild-type and in mutants partially deficient in serine hydroxymethyltransferase.
Topics: Alcohol Oxidoreductases; Amino Acids; Carbon; Folic Acid; Formate-Tetrahydrofolate Ligase; Formates; Glycine; Glycine Hydroxymethyltransferase; Methylenetetrahydrofolate Dehydrogenase (NADP); Mutation; Neurospora; Neurospora crassa; Serine; Species Specificity; Time Factors; Transferases | 1976 |
A simple and practical method for isolation of an early plasmin degradation product of human fibrinogen.
Topics: Electrophoresis, Polyacrylamide Gel; Fibrin Fibrinogen Degradation Products; Fibrinolysin; Glycine; Humans; Immunodiffusion; Methods; Molecular Weight; Proline; Serine; Threonine | 1977 |
[Free amino acid pool in the brain of inbred strains of mice with different learning aptitudes].
Topics: Amino Acids; Animals; Avoidance Learning; Brain; gamma-Aminobutyric Acid; Glutamine; Glycine; Isoleucine; Leucine; Male; Mice; Mice, Inbred Strains; Serine; Taurine | 1977 |
Sequence position of 3-hydroxyproline in basement membrane collagen. Isolation of glycyl-3-hydroxyprolyl-4-hydroxyproline from swine kidney.
Topics: Amino Acid Sequence; Amino Acids; Animals; Basement Membrane; Collagen; Glutamates; Glycine; Hydroxyproline; Kidney Cortex; Microbial Collagenase; Oligopeptides; Serine; Swine | 1975 |
The isolation and partial characterization of neutrophil chemotactic factors from Escherichia coli.
Topics: Acetylation; Alanine; Animals; Ascitic Fluid; Aspartic Acid; Bacterial Proteins; Bacteriological Techniques; Chemotaxis; Chromatography, Gel; Chromatography, Thin Layer; Complement C5; Dansyl Compounds; Electrophoresis, Polyacrylamide Gel; Enzymes; Escherichia coli; Glutamates; Glycine; Neutrophils; Peptides; Periodic Acid; Rabbits; Serine | 1975 |
Effect of amino acid meals on hepatic alpha-aminoisobutyrate transport and cyclic AMP.
Topics: Adrenalectomy; Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Asparagine; Biological Transport; Caseins; Cyclic AMP; Diet; Electrolytes; Gelatin; Glutamine; Glycine; Inulin; Liver; Male; Protein Hydrolysates; Rats; Serine; Sodium Glutamate; Stimulation, Chemical | 1975 |
The influence of sodium, potassium and lanthanum on amino acid release from spinal-medullary synaptosomes.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Depression, Chemical; Electric Stimulation; Female; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine; Hydroxymercuribenzoates; Lactates; Lanthanum; Medulla Oblongata; Ouabain; Potassium; Rats; Serine; Sodium; Spinal Cord; Stimulation, Chemical; Synaptic Transmission; Synaptosomes | 1975 |
Distribution studies of glycine and serine enzymes in chicks.
Topics: Alcohol Oxidoreductases; Animals; Brain; Carbohydrate Dehydrogenases; Chickens; Glutamates; Glyceric Acids; Glycine; Glycine Hydroxymethyltransferase; Kidney; L-Serine Dehydratase; Liver; Myocardium; Phosphoric Monoester Hydrolases; Pyruvates; Serine; Spleen; Transferases | 1975 |
N-terminal amino acid sequences in the major capsid proteins of foot-and-mouth disease virus types A, O, and C.
Topics: Amino Acid Sequence; Amino Acids; Aphthovirus; Asparagine; Aspartic Acid; Dansyl Compounds; Glycine; Leucyl Aminopeptidase; Serine; Serotyping; Threonine; Viral Proteins | 1975 |
Structure of the Mengo virion. IV. Amino- and carboxyl-terminal analyses of the major capsid polypeptides.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aspartic Acid; Capsid; Glutamine; Glycine; Leucine; Mengovirus; Models, Biological; Peptides; Serine; Viral Proteins | 1976 |
Effect of adenosine 3',5'-monophosphate on serine metabolism in chick tissues.
Topics: Animals; Carbohydrate Dehydrogenases; Chickens; Cyclic AMP; Dactinomycin; Glycine; Liver; Phosphoric Monoester Hydrolases; Serine | 1976 |
The formation of peptido-amines from constituent amino acids and histamine in hypothalamic tissue.
Topics: Alanine; Amines; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Cyclic AMP; gamma-Aminobutyric Acid; Glutamine; Glycine; Haplorhini; Histamine; Hypothalamus; Mice; Peptide Biosynthesis; Serine; Swine | 1976 |
Formation of amino acids by cobalt-60 irradiation of hydrogen cyanide solutions.
Topics: Alanine; Amino Acids; Aspartic Acid; Cobalt Radioisotopes; Glutamates; Glycine; Hydrogen Cyanide; Hydrolysis; Serine; Threonine; Valine | 1976 |
Mutational analysis of serine-glycine biosynthesis in Rhodopseudomonas capsulata.
Topics: Carbohydrate Dehydrogenases; Genes; Glycine; Glyoxylates; Mutation; Phosphoric Monoester Hydrolases; Rhodopseudomonas; Serine | 1977 |
A glycine to serine substitution identifies the CYP 3 locus as the structural gene of iso 2 cytochrome c in Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Amino Acids; Cytochrome c Group; Genes; Genetic Code; Glycine; Peptide Fragments; Saccharomyces cerevisiae; Serine | 1977 |
Isolation and partial characterization of a glycine- and serine-rich polypeptide from human serum high-density lipoproteins (HDL).
Topics: Amino Acids; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Glycine; Humans; Lipoproteins, HDL; Peptides; Serine | 1977 |
Oxidation of one-carbon compounds to formate and carbon dioxide in rat liver mitochondria.
Topics: Animals; Carbon Dioxide; Diphosphates; Edetic Acid; Formates; Formyltetrahydrofolates; Glycine; Magnesium; Mitochondria, Liver; Phosphates; Rats; S-Adenosylmethionine; Sarcosine; Serine | 1978 |
Glycine metabolism and spinal cord disorders.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Animals; Ataxia; Cats; Cells, Cultured; Child; Female; Fibroblasts; Glycine; Humans; Male; Serine; Spinal Cord; Spinal Cord Diseases; Synaptic Transmission; Syndrome | 1978 |
Glycine and experimental spinal spasticity.
Topics: Animals; Cats; Dogs; Female; Glucose; Glycine; Neural Inhibition; Serine; Spasm; Spinal Cord Diseases; Synaptic Transmission | 1979 |
Glycine metabolism by Pseudomonas aeruginosa: hydrogen cyanide biosynthesis.
Topics: Carbon Radioisotopes; Glycine; Hydrogen Cyanide; Methionine; Pseudomonas aeruginosa; Serine; Threonine | 1977 |
Effects of modification of the beta 2 subunit and of the alpha2beta2 complex of tryptophan synthase by alpha-cyanoglycine, a substrate analog.
Topics: Catalysis; Dialysis; Enzyme Activation; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Mathematics; Nitriles; Pyridoxal Phosphate; Serine; Spectrophotometry; Temperature; Tryptophan Synthase; Urea | 1975 |
Amino acid composition of experimental salivary pellicles.
Topics: Amino Acids; Blood Group Antigens; Chemical Fractionation; Dental Deposits; Dental Pellicle; Dialysis; Glutamates; Glycine; Hemagglutination Inhibition Tests; Hemagglutination, Viral; Humans; Parotid Gland; Proline; Saliva; Salivary Proteins and Peptides; Serine; Solubility; Submandibular Gland | 1977 |
[Study of a non-collagen protein fraction of dentin during minerlization].
Topics: Amino Acids; Animals; Aspartic Acid; Dentin; Glycine; Phosphorus; Proteins; Serine; Swine; Tooth Calcification | 1977 |
Influence of methionine biosynthesis on serine transhydroxymethylase regulation in Salmonella typhimurium LT2.
Topics: Enzyme Repression; Genes, Regulator; Glycine; Glycine Hydroxymethyltransferase; Methionine; Methionine Adenosyltransferase; Mutation; Salmonella typhimurium; Serine; Transduction, Genetic; Transferases | 1977 |
"Active" one-carbon generation in Saccharomyces cerevisiae.
Topics: Acetates; Aldehyde Oxidoreductases; Carboxy-Lyases; Formates; Glucose; Glycine; Glyoxylates; Mitochondria; Mutation; Oxalates; Saccharomyces cerevisiae; Serine | 1977 |
Transient kinetic studies on the allosteric transition of phosphoglycerate dehydrogenase.
Topics: Alcohol Oxidoreductases; Allosteric Regulation; Carbohydrate Dehydrogenases; Escherichia coli; Glycine; Kinetics; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Time Factors | 1977 |
Alteration of free serum amino acids in voles infected with Trypanosoma brucei gambiense.
Topics: Alanine; Amino Acids; Animals; Arvicolinae; Circadian Rhythm; Glutamates; Glycine; Isoleucine; Leucine; Male; Proline; Serine; Threonine; Trypanosomiasis, African; Tryptophan; Tyrosine; Valine | 1977 |
A new technique for selection of sensitive and auxotrophic mutants of E. coli: isolation of a strain sensitive to an excess of one-carbon metabolites.
Topics: Escherichia coli; Glycine; Methionine; Mutation; Protein Biosynthesis; Serine; Species Specificity; Temperature; Transcription, Genetic | 1977 |
Use of 3H and 14C double-labeled glucose to assess in vivo pathways of amino acid biosynthesis in Escherichia coli.
Topics: Alanine; Amino Acids; Aspartic Acid; Carbon Radioisotopes; Escherichia coli; Glucose; Glutamates; Glycine; Glycolysis; Isoleucine; Leucine; Methionine; Radioactive Tracers; Serine; Tritium; Tyrosine; Valine | 1977 |
[Incorporation of glycine and serine in sideramines of the ferrichrome type with fungi of the genus Aspergillus in vivo and in vitro (author's transl)].
Topics: Aspergillus; Aspergillus fumigatus; Cell-Free System; Ferrichrome; Glucose; Glycine; Peptides, Cyclic; Serine | 1977 |
Growth and amino acid requirements of various strains of group B streptococci.
Topics: Aerobiosis; Amino Acids; Anaerobiosis; Culture Media; Glucose; Glycine; Phosphates; Serine; Species Specificity; Streptococcus agalactiae; Threonine | 1978 |
Selection of Salmonella typhimurium mutants with altered serine transhydroxymethylase regulation.
Topics: Enzyme Repression; Genes; Genes, Regulator; Glycine; Glycine Hydroxymethyltransferase; Mutation; Salmonella typhimurium; Serine; Transduction, Genetic; Transferases | 1978 |
[Effect of n-dipropyl-acetate on the elimination of urinary amino acids].
Topics: Alanine; Amino Acids; Child; Glutamates; Glutamine; Glycine; Histidine; Humans; Male; Ornithine; Serine; Valproic Acid | 1978 |
Correlation between the serine sensitivity and the derepressibility of the ilv genes in Escherichia coli relA- mutants.
Topics: DNA-Directed RNA Polymerases; Enzyme Repression; Escherichia coli; Genes; Glycine; Isoleucine; Methionine; Mutation; Serine | 1978 |
Human transfer factor in vitro. II. Augmentation of the secretion of leucocyte migration inhibitory factor (LIF) by leucocyte dialysate and by its components L-serine and glycine.
Topics: Cells, Cultured; Glycine; Humans; Leukocyte Migration-Inhibitory Factors; Lymphocytes; Lymphokines; Mitogens; Serine; Transfer Factor; Tuberculin | 1979 |
Metabolism of glutathione and a glutathione conjugate by isolated kidney cells.
Topics: Acetaminophen; Animals; Antimycin A; Cell Membrane; Cyanides; Cystine; Glutathione; Glycine; In Vitro Techniques; Kidney; Kinetics; Male; Rats; Serine | 1979 |
Late-onset nonketotic hyperglycinemia and spinocerebellar degeneration.
Topics: Adolescent; Diseases in Twins; Glycine; Humans; Male; Nervous System Diseases; Optic Atrophy; Serine | 1979 |
Structure of the schistosome eggshell: amino acid analysis and incorporation of labelled amino acids.
Topics: Amino Acids; Animals; Aspartic Acid; Carbohydrate Metabolism; Female; Glycine; Lysine; Mice; Ovum; Schistosoma japonicum; Schistosoma mansoni; Serine; Tyrosine | 1979 |
Hydroxy amino acid metabolism in Pseudomonas cepacia: role of L-serine deaminase in dissimilation of serine, glycine, and threonine.
Topics: Amino Acid Oxidoreductases; Enzyme Induction; Glycine; L-Serine Dehydratase; Mutation; Pseudomonas; Serine; Threonine | 1979 |
A new pathway of metabolism of chloramphenicol which influences the interpretation of its irreversible binding to protein in vivo.
Topics: Animals; Blood Proteins; Chemical Phenomena; Chemistry; Chloramphenicol; Glycine; Hydrolysis; In Vitro Techniques; Male; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Serine; Tissue Distribution | 1979 |
[Free amino acids in calf embryos].
Topics: Alanine; Amino Acids; Animals; Cattle; Embryo, Mammalian; Glycine; Histidine; Isoleucine; Leucine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1979 |
[Studies on the metabolism of parenterally infused amino acids in healthy adults].
Topics: Adult; Alanine; Amino Acids; Female; Glycine; Humans; Infusions, Parenteral; Male; Methionine; Serine; Sex Factors | 1977 |
Diurnal variations in plasma concentrations of tryptophan, tryosine, and other neutral amino acids: effect of dietary protein intake.
Topics: Adult; Alanine; Amino Acids; Circadian Rhythm; Dietary Proteins; Glycine; Humans; Isoleucine; Leucine; Male; Middle Aged; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1979 |
The effect of replacement of L-alanine residue by glycine, L-serine or D-alanine in an N-acetylmuramyl-L-alanyl-D-isoglutamine on immunoadjuvancies of molecules.
Topics: Adjuvants, Immunologic; Alanine; Animals; Antibody Formation; Chemical Phenomena; Chemistry; Cornea; Female; Glycine; Glycopeptides; Guinea Pigs; Hypersensitivity, Delayed; Immunoglobulin G; Ovalbumin; Serine; Stereoisomerism | 1977 |
Solvent accessibilities in glycyl, alanyl and seryl dipeptides.
Topics: Alanine; Chymotrypsin; Dipeptides; Glycine; Hydrogen Bonding; Models, Chemical; Muramidase; Protein Conformation; Serine; Solvents | 1977 |
Serum-mediated regulation of amino acid transport in cultured chick embryo fibroblasts.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport, Active; Blood; Cells, Cultured; Culture Media; DNA; Glycine; Kinetics; Proline; Serine | 1977 |
[Nitrogen-economy and synthesis of serine and glycine in reticulocytes].
Topics: Glutamates; Glycine; Humans; Nitrogen; Oxygen Consumption; Pyruvates; Reticulocytes; Serine | 1977 |
The synthesis of oxylate from hydroxypyruvate by isolated perfused rat liver. The mechanism of hyperoxaluria in L-glyceric aciduria.
Topics: Acetaldehyde; Amino Acid Metabolism, Inborn Errors; Animals; Ethanolamines; Glyceric Acids; Glycine; Glycolates; Glyoxylates; Liver; Oxalates; Pyruvates; Rats; Serine | 1978 |
Concentrations of glutamic acid in cerebellar cortex and deep nuclei of normal mice and Weaver, Staggerer and nervous mutants.
Topics: Animals; Aspartic Acid; Cerebellar Cortex; Cerebellar Diseases; Cerebellar Nuclei; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine; Mice; Mice, Inbred Strains; Mutation; Nerve Tissue Proteins; Purkinje Cells; Serine; Taurine | 1978 |
The effect of homocysteine, methionine, serine and glycine on DNA synthesis by human normoblastic and megaloblastic bone marrow cells.
Topics: Bone Marrow Cells; Cell Survival; Deoxyuridine; DNA; Erythrocytes, Abnormal; Glycine; Homocysteine; Humans; Megaloblasts; Methionine; Serine; Thymidine | 1978 |
Transamination of branched-chain keto acids by isolated perfused rat kidney.
Topics: Amino Acids; Animals; Glycine; In Vitro Techniques; Keto Acids; Kidney; Male; Perfusion; Rats; Serine; Taurine; Transaminases | 1978 |
Uptake of L-alanine, glycine and L-serine in the pigeon central nervous system.
Topics: Alanine; Animals; Biological Transport, Active; Cell Fractionation; Columbidae; Glycine; Hypotonic Solutions; Kinetics; Mitochondria; Potassium; Serine; Sodium; Spinal Cord; Superior Colliculi; Telencephalon; Temperature | 1978 |
Human transfer factor in vitro: identification of L-serine and glycine as components with augmenting effect in lymphocyte transformation assay.
Topics: Adsorption; Agglutinins; Cells, Cultured; Chemical Fractionation; Chromatography, Gel; Glycine; Humans; Leukocytes; Lymphocyte Activation; Serine; Transfer Factor; Tuberculin | 1978 |
Studies on soybean trypsin inhibitors. IV. Change of the inhibitory activity of Bowman-Birk inhibitor upon replacements of the alpha-chymotrypsin reactive site serine residue by other amino acids.
Topics: Alanine; Binding Sites; Chymotrypsin; Glycine; Leucine; Serine; Structure-Activity Relationship; Trypsin Inhibitor, Bowman-Birk Soybean; Trypsin Inhibitors; Valine | 1978 |
Specific glycine uptake by identified neurons of Aplysia californica. II. Biochemistry.
Topics: Alanine; Animals; Aplysia; Biological Transport, Active; Culture Techniques; Ganglia; Glycine; Leucine; Neurons; Osmolar Concentration; Serine; Sodium; Temperature | 1978 |
Purine metabolism in Leishmania donovani and Leishmania braziliensis.
Topics: Formates; Glycine; Kinetics; Leishmania; Purine Nucleosides; Purine Nucleotides; Purines; Serine; Species Specificity | 1978 |
Discrimination between different entry mechanisms for neutral amino acids in rabbit ileal mucosa.
Topics: Amino Acids; Animals; Biological Transport; Glycine; Ileum; In Vitro Techniques; Intestinal Mucosa; Kinetics; Phenylalanine; Rabbits; Serine | 1978 |
Interrelated changes of amino acids in the retina and optic tectum of a marine fish with alterations of illuminating conditions.
Topics: Amino Acids; Animals; Aspartic Acid; Dark Adaptation; Fishes; gamma-Aminobutyric Acid; Glutamates; Glycine; Photic Stimulation; Retina; Serine; Superior Colliculi; Taurine; Threonine | 1978 |
[Role of folic acid in the physiology of the central nervous system].
Topics: Animals; Central Nervous System; Folic Acid; Glutamates; Glycine; Methylation; Purines; Rabbits; Serine | 1978 |
The use of glycine as nitrogen source by Escherichia coli K12.
Topics: Amino Acids; Cell Division; Escherichia coli; Glycine; Glycine Hydroxymethyltransferase; L-Serine Dehydratase; Nitrogen; Serine; Time Factors | 1976 |
A rapid test for the rel A mutation in E. coli.
Topics: Cell Division; Escherichia coli; Glycine; Methionine; Mutation; Serine; Species Specificity; Time Factors | 1976 |
The conversion of leucine to alpha-ketoisocaproic acid and its metabolic consequences for Escherichia coli K12.
Topics: Ammonium Sulfate; Caproates; Escherichia coli; Glycine; Keto Acids; Leucine; Serine; Stereoisomerism | 1976 |
Biochemical observations following administration of taurine to patients with epilepsy.
Topics: Adolescent; Adult; Alanine; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Female; Glutamates; Glutamine; Glycine; Humans; Male; Middle Aged; Serine; Taurine; Time Factors | 1975 |
Studies on human dental plaque. 1. Physical and chemical characteristics and enzyme activities of pooled plaque extracts.
Topics: Alanine; Amylases; Betaine; Dental Caries; Dental Plaque; Glutamates; Glycine; Humans; Leucine; Muramidase; Periodontal Diseases; Saliva; Serine; Valine | 1975 |
[Physiological changes of amino acid secretion in 24-hour urine in adults].
Topics: Adult; Alanine; Amino Acids; Aminobutyrates; Chromatography; Cystinuria; Glycine; Humans; Lysine; Male; Middle Aged; Serine; Time Factors | 1975 |
Oxidative phosphorylation during glycollate metabolism in mitochondria from phototrophic Euglena gracilis.
Topics: Antimycin A; Euglena gracilis; Flavoproteins; Glyceric Acids; Glycine; Glycolates; Glyoxylates; Mitochondria; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen; Oxygen Consumption; Phosphorus; Rotenone; Serine; Transaminases | 1975 |
[Amino acid pattern in endemic (Balkan-)nephropathy (author's transl)].
Topics: Adolescent; Adult; Alanine; Amino Acids; Bulgaria; Child; Citrulline; Cystine; Disease Reservoirs; Female; Glycine; Humans; Isoleucine; Leucine; Male; Methionine; Nephritis, Interstitial; Ornithine; Phenylalanine; Proline; Romania; Serine; Yugoslavia | 1976 |
The variability of human lambda-chain constant regions and some relationships to V-regions sequences.
Topics: Alanine; Amino Acid Sequence; Chromatography, Gel; Chromatography, Ion Exchange; Cystine; Electrophoresis, Paper; Glutamates; Glycine; Humans; Immunoglobulin lambda-Chains; Immunoglobulin Light Chains; Isoleucine; Leucine; Peptides; Proline; Serine; Thiazoles; Threonine; Valine | 1976 |
[Histochemical evidence of aminotransferases. VII. Quantitative histochemical and biochemical investigations of the amino-transferases of branched chain amino acids, glycine and serine in the rat organs during development (author's transl)].
Topics: Animals; Animals, Newborn; Brain; Embryo, Mammalian; Glycine; Growth; Histocytochemistry; Isoenzymes; Kidney; Liver; Muscles; Myocardium; Rats; Serine; Transaminases | 1976 |
Variations in the concentrations of blood plasma free amino acids in suckled and fasted neonatal pigs.
Topics: Amino Acids; Animals; Animals, Newborn; Arginine; Cystine; Fasting; Glycine; Leucine; Lysine; Proline; Serine; Swine; Threonine; Tyrosine | 1977 |
Serine transhydroxymethylase: evidence for a sequential random mechanism.
Topics: Animals; Folic Acid; Glycine; Glycine Hydroxymethyltransferase; Kinetics; Liver; Rabbits; Serine; Spectrophotometry; Threonine; Transferases | 1977 |
Comparison of transport at the anterior and posterior surfaces of the calf lens.
Topics: Alanine; Amino Acids; Animals; Arginine; Biological Transport; Cattle; Cysteine; Epithelium; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Kinetics; Lens, Crystalline; Leucine; Serine | 1977 |
[Folic acid metabolism in Lesch-Nythan syndrome].
Topics: Folic Acid; Glycine; Histidine; Humans; Lesch-Nyhan Syndrome; Methionine; Serine | 1977 |
Hormone-fuel concentrations in anephric subjects. Effect of hemodialysis (with special reference to amino acids).
Topics: Adult; Amino Acids; Antigens; Blood Glucose; Cholesterol; Female; Glucagon; Glycine; Hormones; Humans; Insulin; Lactates; Male; Middle Aged; Nephrectomy; Pyruvates; Renal Dialysis; Serine; Triglycerides | 1976 |
Compartmentation of albumin and ferritin synthesis in rat liver in vivo.
Topics: Animals; Female; Ferritins; Glycine; Liver; Rats; Serine; Serum Albumin | 1976 |
Serine auxotrophy of myoblasts in primary and secondary culture.
Topics: Animals; Animals, Newborn; Cell Line; Cells, Cultured; Fluorides; Glycine; Muscles; Rats; Serine | 1976 |
Intramitochondrial localization and proposed metabolic significance of serine transhydroxymethylase.
Topics: Animals; Azo Compounds; Benzenesulfonates; Digitonin; Folic Acid; Glycine; Glycine Hydroxymethyltransferase; Membranes; Mitochondria, Liver; Mitochondrial Swelling; Models, Biological; Rats; Serine; Tetrahydrofolates; Transferases | 1976 |
Turnover of amino-terminal acetylated and non-acetylated hemoglobins in vivo.
Topics: Acetates; Animals; Arginine; Asparagine; Blood Cell Count; Cats; Glycine; Hematocrit; Hemoglobins; Hemoglobins, Abnormal; Kinetics; Lysine; Phenotype; Reticulocytes; Serine; Time Factors | 1976 |
The regulation of the degradation of methionine and of the one-carbon units derived from histidine, serine and glycine.
Topics: Animals; Carbon Dioxide; Enzyme Activation; Folic Acid; Formates; Formiminoglutamic Acid; Gluconeogenesis; Glucose; Glycine; Histidine; Homocysteine; In Vitro Techniques; Liver; Methionine; Oxidoreductases Acting on CH-NH Group Donors; Perfusion; Rats; Serine; Tetrahydrofolates | 1976 |
Phosphoserine as an early product of photosynthesis in isolated chloroplasts and in leaves of Zea mays seedlings.
Topics: Amino Acids; Aspartic Acid; Chloroplasts; Glycine; Organophosphorus Compounds; Photosynthesis; Plants; Serine; Zea mays | 1976 |
Alterative metabolic pathway of rats suffered from thiamine deficiency.
Topics: Animals; Carbon Dioxide; Female; Formates; Glucose; Glycine; Glyoxylates; Liver; Male; Rats; Serine; Thiamine Deficiency; Thiamine Pyrophosphate | 1976 |
Responses of Megalodiscus temperatus miracidia to amino and sialic acids found in snail-conditioned water.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Glutamine; Glycine; Serine; Sialic Acids; Snails; Trematoda; Water | 1976 |
Turnover of transfer RNA species during development of the posterior silkgland of Bombyx mori L.
Topics: Alanine; Animals; Aspartic Acid; Bombyx; Glycine; Larva; Metamorphosis, Biological; RNA, Transfer; Sebaceous Glands; Serine; Threonine; Time Factors | 1976 |
Metabolism of L-threonine and its relationship to sclerotium formation in Sclerotium rolfsii.
Topics: Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Carboxy-Lyases; Coenzyme A Ligases; Cycloheximide; Glucosyltransferases; Glycine; Glycine Hydroxymethyltransferase; Glyoxylates; Mitomycins; Mitosporic Fungi; Morphogenesis; Oxalates; Oxo-Acid-Lyases; p-Fluorophenylalanine; Serine; Stereoisomerism; Threonine | 1976 |
Effects of serine on morphine-dependent mice.
Topics: Animals; Brain; Drug Tolerance; Glycine; Humans; Male; Mice; Morphine Dependence; Nalorphine; Serine; Strychnine; Substance Withdrawal Syndrome | 1976 |
Failure of 3H-serine to induce radioactivity in presumed glycinergic retinal neurons.
Topics: Animals; Autoradiography; Glycine; Rabbits; Retina; Serine; Tritium | 1976 |
A chemotactic receptor for val(ala)-gly-ser-glu on human.
Topics: Alanine; Chemotaxis, Leukocyte; Eosinophils; Glutamine; Glycine; Receptors, Drug; Serine; Valine | 1976 |
Importance of sarcosine formation in methionine methyl carbon oxidation in the rat.
Topics: Acetates; Animals; Carbon Dioxide; Dose-Response Relationship, Drug; Glycine; Liver; Male; Methionine; Oxidation-Reduction; Rats; Sarcosine; Serine; Urine | 1976 |
Evidence for S-adenosylmethionine independent catabolism of methionine in the rat.
Topics: Animals; Carbon Dioxide; Cysteine; Formaldehyde; Formates; Glycine; Liver; Male; Methionine; Rats; S-Adenosylmethionine; Serine | 1976 |
The effect of feeding various levels of dietary glycine in a pre-experimental diet to one-day old chicks on their subsequent glycine plus serine requirement.
Topics: Animal Feed; Animals; Body Weight; Caseins; Chickens; Glycine; Male; Nutritional Requirements; Serine; Zea mays | 1976 |
Amino acid metabolism in Friedreich's ataxia.
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Friedreich Ataxia; Glycine; Histidine; Humans; Isoleucine; Ornithine; Phenylalanine; Phosphatidylethanolamines; Sarcosine; Serine; Taurine; Tyrosine; Valine | 1976 |
Metabolism of methionine and biosynthesis of caffeine in the tea plant (Camellia sinensis L.).
Topics: Adenosine Monophosphate; Caffeine; Glycine; Guanine Nucleotides; Methionine; Methylation; Nucleic Acids; Serine; Tea; Time Factors; Xanthines | 1976 |
Plasma amino acids in children and adolescents on hemodialysis.
Topics: Adolescent; Amino Acids; Child; Child Nutritional Physiological Phenomena; Citrulline; Diet; Female; Glycine; Growth; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methylhistidines; Nutritional Physiological Phenomena; Proline; Renal Dialysis; Serine; Tyrosine; Valine | 1976 |
The amino acids of M and N blood group glycopeptides are different.
Topics: Amino Acids; Erythrocytes; Glutamates; Glycine; Glycopeptides; Humans; Leucine; MNSs Blood-Group System; Serine | 1976 |
A highly stereospecific synthesis of (R)- and (S)-[2-3H]Glycine.
Topics: Glycine; Isotope Labeling; Serine; Spectrum Analysis; Stereoisomerism | 1976 |
Amino acid composition, distribution and origin of "tuft" protein in human and bovine dental enamel.
Topics: Alanine; Amelogenesis; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Dental Enamel; Dental Enamel Proteins; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Free amino acids and amines in human dental plaque.
Topics: Alanine; Amines; Amino Acids; Aminobutyrates; Aspartic Acid; Cadaverine; Chemical Fractionation; Chromatography, Thin Layer; Dansyl Compounds; Dental Plaque; Fluorescence; Fluorometry; Glutamates; Glycine; Histamine; Humans; Ion Exchange; Lysine; Proline; Putrescine; Serine; Threonine; Valine | 1975 |
Distribution and metabolism of chlormequat (CCC) in potato- and wheat plants.
Topics: Carbon Dioxide; Chlormequat; DNA; Glycine; Plants, Edible; Quaternary Ammonium Compounds; RNA; Serine; Species Specificity; Time Factors; Triticum | 1975 |
Studies on convulsants in the isolated frog spinal cord. I. Antagonism of amino acid responses.
Topics: Alanine; Amino Acids; Aminocaproates; Aminoisobutyric Acids; Animals; Asparagine; Bicuculline; Convulsants; Cystathionine; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Imidazoles; In Vitro Techniques; Isomerism; Leucine; Membrane Potentials; Nerve Endings; Neurons, Afferent; Picrotoxin; Rana pipiens; Serine; Spinal Cord; Strychnine; Taurine; Threonine; Valine | 1975 |
Transport properties of merodiploids covering the dagA locus in Escherichia coli K-12.
Topics: Alanine; Biological Transport, Active; Cell Membrane; Diploidy; Escherichia coli; Genes; Glycerol; Glycine; Kinetics; Leucine; Mutation; Proline; Serine; Stereoisomerism | 1975 |
Functional adaptation of aminoacyl-tRNA synthetases to fibroin biosynthesis in the silkgland of Bombyx mori L.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Bombyx; Fibroins; Glycine; Larva; Leucine; Metamorphosis, Biological; Protein Biosynthesis; Serine; Time Factors | 1975 |
Serine transhydroxymethylase. Relaxation and transient kinetic study of the formation and interconversion of the enzyme-glycine complexes.
Topics: Glycine; Kinetics; Oscillometry; Protein Binding; Serine; Spectrophotometry; Tetrahydrofolates; Thermodynamics; Transferases | 1975 |
A study on the effect of folate deficiency on the incorporation of 14-C labelled glycine, serine and leucine into the oviduct protein of the oestrogen-treated, immature female domestic fowl.
Topics: Animals; Chickens; Estradiol; Female; Folic Acid; Folic Acid Deficiency; Glycine; Leucine; Organ Size; Oviducts; Protein Biosynthesis; Serine; Time Factors | 1975 |
Nonketotic hyperglycinemia. Glycine accumulation due to absence of glycerine cleavage in brain.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Brain; Brain Chemistry; Child; Female; Glycine; Humans; Infant; Infant, Newborn; Liver; Serine; Transferases | 1975 |
The requirements of the brain for some amino acids.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Brain; Carbon Radioisotopes; Glycine; Kinetics; Proline; Rats; Serine; Sulfur Radioisotopes; Time Factors | 1975 |
Compartmentation of amino acid metabolism in the rat posterior pituitary.
Topics: Acetates; Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Radioisotopes; Dansyl Compounds; gamma-Aminobutyric Acid; Glucose; Glutamates; Glycine; Pituitary Gland, Posterior; Rats; Serine; Taurine; Tritium | 1975 |
Stimulated amino acid imbalance and histidine transport in rat brain slices.
Topics: Alanine; Amino Acids; Amino Acids, Dicarboxylic; Amino Acids, Essential; Aminoisobutyric Acids; Animals; Biological Transport, Active; Brain; Brain Chemistry; Diet; Dietary Proteins; Dose-Response Relationship, Drug; Glycine; Histidine; Kinetics; Male; Phenylalanine; Rats; Serine | 1975 |
Mechanistic, inhibitory and stereochemical studies on cytoplasmic and mitochondrial serine transhydorxymethylases.
Topics: Acetaldehyde; Aldehydes; Animals; Catalysis; Cytoplasm; Epoxy Compounds; Formaldehyde; Glycine; Glycine Hydroxymethyltransferase; Iodoacetamide; Isoenzymes; Mitochondria, Liver; Rabbits; Serine; Tetrahydrofolates; Threonine; Transferases | 1975 |
Chemical and physical characteristics of a phosphoprotein from human parotid saliva.
Topics: Amino Acids, Dicarboxylic; Carbohydrates; Glycine; Hexosamines; Humans; Isoelectric Focusing; Magnetic Resonance Spectroscopy; Models, Structural; Molecular Weight; Parotid Gland; Peptide Chain Termination, Translational; Phosphates; Phosphoproteins; Proline; Protein Conformation; Saliva; Serine | 1975 |
Sequential polypeptides. Part X. The synthesis of some sequential polypeptide collagen models with functional side-chains.
Topics: Amino Acid Sequence; Collagen; Glutamine; Glycine; Lysine; Peptides; Proline; Serine; Tyrosine | 1975 |
Methionine toxicity in the chick: nutritional and metabolic implications.
Topics: Adenine; Amino Acids; Animals; Arginine; Blood Glucose; Body Weight; Chickens; Glycine; Hypoglycemia; Isoleucine; Male; Methionine; Serine; Threonine | 1975 |
[Isolation and amino acid composition of two pathologically augmented proteins from psoriatic scales (author's transl)].
Topics: Alanine; Amino Acids; Electrophoresis, Disc; Galactosamine; Glycine; Humans; Leucine; Proteins; Psoriasis; Serine; Skin; Threonine | 1975 |
Relative utilization of serine and glycine by chicks.
Topics: Animal Feed; Animals; Body Weight; Chickens; Cystine; Feces; Glutamine; Glycine; Glycine max; Male; Serine; Uric Acid; Zea mays | 1975 |
The effect of methionine on the metabolism of serine and glycine in vitamin B-12-deficient rats.
Topics: Animals; Folic Acid Deficiency; Glycine; Liver; Male; Methionine; Perfusion; Rats; Serine; Vitamin B 12 Deficiency | 1975 |
[Some indices of nitrogen metabolism in patients with viral hepatitis].
Topics: Adolescent; Adult; Alanine; Ammonia; Asparagine; Chronic Disease; Cysteine; Cystinuria; Glutamates; Glycine; Hepatitis A; Humans; Isoleucine; Leucine; Methionine; Middle Aged; Nitrogen; Phenylalanine; Serine; Threonine; Urea; Valine | 1975 |
Biochemical components of the photosynthetic CO2 compensation point of higher plants.
Topics: Aspartic Acid; Carbon Dioxide; Glyceric Acids; Glycerophosphates; Glycine; Hordeum; Kinetics; Malates; Photosynthesis; Plants; Serine; Species Specificity | 1975 |
Purification of human placenta phenylalanine, valine, methionine, glucine, and serine transfer ribonucleic acids.
Topics: Chromatography, High Pressure Liquid; Female; Glycine; Humans; Methionine; Phenylalanine; Placenta; Pregnancy; RNA, Transfer; Serine; Valine | 1975 |
Characterization of neutral amino acid transport in a marine pseudomonad.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport, Active; Glycine; Isoleucine; Kinetics; Leucine; Mutation; Pseudomonas; Seawater; Serine; Stereoisomerism; Threonine; Valine; Water Microbiology | 1975 |
Compartmentalization of amino acids in surfactant aggregates. Partitioning between water and aqueous micellar sodium deodecanoate and between hexane and dodecylammonium propionate trapped water in hexane.
Topics: Alanine; Alkanes; Amino Acids; Arginine; Aspartic Acid; Colloids; Glutamates; Glycine; Isoleucine; Laurates; Leucine; Lysine; Micelles; Phenylalanine; Proline; Serine; Solubility; Threonine; Valine | 1975 |
[Free amino acids in the amniotic fluid and in maternal blood in advanced pregnancy].
Topics: Alanine; Amino Acids; Amniotic Fluid; Cysteine; Female; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Pregnancy Trimester, Third; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
[Studies on the modification of methionine imbalance in rats through the supplementation of threonine, serine, glycine or glutamic acid].
Topics: Animal Feed; Animals; Food Additives; Glutamates; Glycine; Methionine; Rats; Serine; Threonine | 1975 |
Retinal degeneration in cats fed casein. I. Taurine deficiency.
Topics: Animals; Caseins; Cats; Cysteine; Dietary Proteins; DNA; Eating; Electroretinography; Glutamine; Glycine; Methionine; Retina; Retinal Degeneration; Serine; Taurine | 1976 |
Specific release of endogenous glutamate from piriform cortex stimulated in vitro.
Topics: Animals; Calcium; Cerebral Cortex; Electric Stimulation; Glutamates; Glutamine; Glycine; Guinea Pigs; In Vitro Techniques; Olfactory Pathways; Serine | 1976 |
Quantitative adaptation of isoacceptor tRNAs to mRNA codons of alanine, glycine and serine.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Bombyx; Codon; Glycine; RNA, Messenger; RNA, Transfer; RNA, Viral; Serine | 1976 |
[The pattern of distribution of free amino acids in human amniotic fluid related to the duration of pregnancy. Part I: Changes in concentration in normal pregnancy (author's transl)].
Topics: Alanine; Amino Acids; Amniotic Fluid; Chromatography, Gas; Cysteine; Female; Gestational Age; Glycine; Humans; Hydroxyproline; Methionine; Ornithine; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1976 |
Glycine-serine interrelations in the chick.
Topics: Animals; Chickens; Folic Acid Deficiency; Glycine; Liver; Nutritional Requirements; Serine; Uric Acid | 1976 |
Isolation and characterization of an abundant elastase inhibitor from NaCl extracts of bovine nasal septa and articular cartilage.
Topics: Amino Acids; Animals; Cartilage, Articular; Cattle; Culture Techniques; Electrophoresis, Polyacrylamide Gel; Glycine; Humans; Kinetics; Nasal Septum; Pancreatic Elastase; Proteins; Serine; Sodium Chloride | 1992 |
The 93 kDa protein gephyrin and tubulin associated with the inhibitory glycine receptor are phosphorylated by an endogenous protein kinase.
Topics: Animals; Carrier Proteins; Glycine; Kinetics; Membrane Proteins; Phosphorylation; Protein Kinases; Rats; Receptors, Glycine; Receptors, Neurotransmitter; Serine; Threonine; Tubulin | 1992 |
Induction of feeding by 7-chlorokynurenic acid, a strychnine-insensitive glycine binding site antagonist.
Topics: Analysis of Variance; Animals; Ataxia; Dose-Response Relationship, Drug; Feeding Behavior; Glycine; Injections, Intraventricular; Kynurenic Acid; Male; Muscle Contraction; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine; Strychnine | 1992 |
Mechanism of glycine protection in hypoxic injury: analogies with glycine receptor.
Topics: Animals; Dose-Response Relationship, Drug; Glycine; Hypoxia; In Vitro Techniques; Kidney; Kynurenic Acid; Male; Perfusion; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, Neurotransmitter; Serine | 1992 |
Dynorphin increases extracellular levels of excitatory amino acids in the brain through a non-opioid mechanism.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Dialysis; Dynorphins; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine; Kinetics; Male; Neurotransmitter Agents; Peptide Fragments; Rats; Rats, Inbred Strains; Serine; Stereotaxic Techniques; Taurine; Threonine | 1992 |
pH and kinetic isotope effects on the reductive half-reaction of D-amino acid oxidase.
Topics: Alanine; D-Amino-Acid Oxidase; Deuterium; Glycine; Hydrogen-Ion Concentration; Isotope Labeling; Kinetics; Mathematics; Models, Theoretical; Serine | 1992 |
In vitro and in vivo characterization of the NMDA receptor-linked strychnine-insensitive glycine site.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Dizocilpine Maleate; Glycine; Kynurenic Acid; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Serine; Stereoisomerism; Strychnine | 1992 |
An osteonectin-like protein in the matrix of cultured osteogenic cell-line MC3T3-E1, which is associated with calcification.
Topics: Amino Acid Sequence; Animals; Calcification, Physiologic; Cell Line; Collagen; Extracellular Matrix; Glutamates; Glutamic Acid; Glycine; Mice; Molecular Sequence Data; Molecular Weight; Osteoblasts; Osteonectin; Serine | 1992 |
Limbic seizure-induced changes in extracellular amino acid levels in the hippocampal formation: a microdialysis study of freely moving rats.
Topics: Amino Acids; Amygdala; Animals; Aspartic Acid; Brain Mapping; Chromatography, High Pressure Liquid; Dialysis; Extracellular Space; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kainic Acid; Limbic System; Male; Rats; Rats, Wistar; Seizures; Serine; Synaptic Transmission | 1992 |
13C NMR detection of folate-mediated serine and glycine synthesis in vivo in Saccharomyces cerevisiae.
Topics: Aminohydrolases; Cytosol; Folic Acid; Formate-Tetrahydrofolate Ligase; Formates; Glycine; Isoenzymes; Magnetic Resonance Spectroscopy; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondria; Multienzyme Complexes; Saccharomyces cerevisiae; Serine | 1992 |
Alpha-helix stability in proteins. I. Empirical correlations concerning substitution of side-chains at the N and C-caps and the replacement of alanine by glycine or serine at solvent-exposed surfaces.
Topics: Alanine; Bacterial Proteins; Enzyme Stability; Glycine; Mutagenesis; Protein Denaturation; Ribonucleases; Serine; Solvents; Thermodynamics; Urea | 1992 |
Seizure related elevations of extracellular amino acids in human focal epilepsy.
Topics: Amino Acids; Asparagine; Aspartic Acid; Cerebral Cortex; Dialysis; Electroencephalography; Epilepsies, Partial; Extracellular Space; Glutamates; Glycine; Humans; Seizures; Serine | 1992 |
Glycine enhances extracellular 45Ca2+ response to NMDA application investigated with microdialysis of rabbit hippocampus in vivo.
Topics: Amino Acids; Animals; Calcium; Calcium Radioisotopes; Dialysis; Drug Synergism; Extracellular Space; Glycine; Hippocampus; Kynurenic Acid; N-Methylaspartate; Rabbits; Receptors, N-Methyl-D-Aspartate; Serine | 1992 |
Fetal serine fluxes across fetal liver, hindlimb, and placenta in late gestation.
Topics: Animals; Carbon Dioxide; Decarboxylation; Female; Fetal Blood; Fetus; Gestational Age; Glycine; Hindlimb; Liver; Osmolar Concentration; Placenta; Pregnancy; Serine; Sheep | 1992 |
[The intravascular transfer of glycine during percutaneous kidney surgery].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Glycine; Hemodilution; Humans; Male; Middle Aged; Nephrostomy, Percutaneous; Prospective Studies; Serine; Sodium; Syndrome; Therapeutic Irrigation; Threonine | 1992 |
Prenatal diagnosis of non-ketotic hyperglycinaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Aminomethyltransferase; Amniotic Fluid; Chorionic Villi; Female; Glycine; Humans; Hydroxymethyl and Formyl Transferases; Pregnancy; Pregnancy Outcome; Prenatal Diagnosis; Serine; Transferases | 1992 |
Characterization of three osteogenesis imperfecta collagen alpha 1(I) glycine to serine mutations demonstrating a position-dependent gradient of phenotypic severity.
Topics: Amino Acid Sequence; Base Sequence; Child; Collagen; Female; Glycine; Hot Temperature; Humans; Infant; Infant, Newborn; Male; Molecular Sequence Data; Mutation; Nucleic Acid Heteroduplexes; Osteogenesis Imperfecta; Phenotype; Protein Denaturation; RNA, Messenger; Serine | 1992 |
Catalytic site in the beta subunit of H(+)-ATPase from Escherichia coli:the glycine-rich sequence and its interaction with Ser-174.
Topics: Adenosine Triphosphatases; Adenylyl Cyclases; Amino Acid Sequence; Catalysis; Cation Transport Proteins; Escherichia coli; Glycine; Molecular Sequence Data; Mutation; Serine | 1992 |
The role of anticodon bases and the discriminator nucleotide in the recognition of some E. coli tRNAs by their aminoacyl-tRNA synthetases.
Topics: Amino Acyl-tRNA Synthetases; Anticodon; Asparagine; Bacteriophage T7; Base Sequence; Cysteine; DNA-Directed RNA Polymerases; Escherichia coli; Glycine; Histidine; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Transfer; Serine; Structure-Activity Relationship; Substrate Specificity | 1992 |
Glycine absorption from irrigation fluid during endoscopic resection of rectal tumours.
Topics: Aged; Endoscopy; Female; Glycine; Humans; Male; Middle Aged; Osmolar Concentration; Rectal Neoplasms; Serine; Sodium; Therapeutic Irrigation | 1992 |
Characterization of the formate (for) locus, which encodes the cytosolic serine hydroxymethyltransferase of Neurospora crassa.
Topics: Amino Acid Sequence; Base Sequence; Cytosol; Enzyme Induction; Formates; Gene Expression Regulation, Fungal; Genes, Fungal; Glycine; Glycine Hydroxymethyltransferase; Isoenzymes; Molecular Sequence Data; Neurospora crassa; Restriction Mapping; RNA, Messenger; Sequence Homology, Nucleic Acid; Serine | 1992 |
Effects of substitutions of glycine and asparagine for serine132 on activity and binding of human lipoprotein lipase to very low density lipoproteins.
Topics: Amino Acid Sequence; Animals; Asparagine; Base Sequence; Catalysis; Cells, Cultured; Chlorocebus aethiops; Cross Reactions; Enzyme Activation; Glycine; Humans; Lipoprotein Lipase; Lipoproteins, VLDL; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Serine; Triolein | 1992 |
Mild dominant osteogenesis imperfecta with intrafamilial variability: the cause is a serine for glycine alpha 1(I) 901 substitution in a type-I collagen gene.
Topics: Base Sequence; Child; Chromosome Aberrations; Codon; Collagen; DNA Mutational Analysis; Female; Gene Expression; Genes; Genes, Dominant; Genetic Variation; Glycine; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation; Osteogenesis Imperfecta; Pedigree; Polymerase Chain Reaction; Procollagen; RNA, Messenger; Serine | 1992 |
Purification and microsequencing of the intra-acrosomal protein SP-10. Evidence that SP-10 heterogeneity results from endoproteolytic processes.
Topics: Acrosome; Amino Acid Sequence; Antibodies, Monoclonal; Antigens; Blotting, Western; Chromatography, Affinity; Chromatography, High Pressure Liquid; DNA; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Glutamates; Glycine; Gonadal Steroid Hormones; Humans; Male; Membrane Proteins; Molecular Sequence Data; Polymorphism, Genetic; Proline; Serine | 1992 |
The influence of strychnine-insensitive glycine receptor agonists and antagonists on generalized seizure thresholds.
Topics: Alanine; Amygdala; Animals; Glycine; Kindling, Neurologic; Kynurenic Acid; Male; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Serine; Strychnine | 1991 |
Characterization of serine's inhibitory action on neurons in the mudpuppy retina.
Topics: Animals; Aspartic Acid; Bicuculline; Calcium; Cobalt; Darkness; Electric Conductivity; Evoked Potentials, Visual; gamma-Aminobutyric Acid; Glutamine; Glycine; In Vitro Techniques; Membrane Potentials; Necturus; Photic Stimulation; Retina; Retinal Ganglion Cells; Serine; Strychnine; Synapses; Synaptic Transmission | 1991 |
Anticonvulsant drug potentiation by glycine in maximal electroshock seizures is mimicked by D-serine and antagonized by 7-chlorokynurenic acid.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Electroshock; Glycine; Kynurenic Acid; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Serine | 1991 |
Evidence for involvement of endogenous glycine in the induction of long-term potentiation in the dentate gyrus of anesthetized rats.
Topics: Anesthesia; Animals; Electric Stimulation; Glycine; Hippocampus; Kynurenic Acid; Male; Neuronal Plasticity; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Synaptic Transmission; Time Factors | 1991 |
Chemical analysis and scanning electron microscopy of acquired pellicle formed in vivo on stannous fluoride treated enamel.
Topics: Amino Acids; Dental Deposits; Dental Enamel; Dental Pellicle; Glutamates; Glutamic Acid; Glycine; Humans; Microscopy, Electron, Scanning; Serine; Tin Fluorides | 1991 |
Plasma serine in schizophrenics and controls measured by gas chromatography-mass spectrometry.
Topics: Adult; Antipsychotic Agents; Female; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Male; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Serine | 1991 |
Evidence for heterogenous glycine domains but conserved multiple states of the excitatory amino acid recognition site of the NMDA receptor: regional binding studies with [3H]glycine and [3H]L-glutamate.
Topics: Animals; Autoradiography; Binding, Competitive; Cerebellar Cortex; Cerebral Cortex; Cycloserine; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Kynurenic Acid; Ligands; Male; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Serine | 1991 |
Amino acid composition of acquired enamel pellicle collected in vivo after 2 hours and after 24 hours.
Topics: Amino Acids; Dental Deposits; Dental Enamel; Dental Pellicle; Diet; Fasting; Glutamates; Glutamic Acid; Glycine; Humans; Proline; Serine; Time Factors | 1991 |
Presence of the HNK-1 epitope (3-sulfoglucuronic acid) on oligosaccharides from squid skin chondroitin proteoglycans and degradation of proteoglycans by proteolytic enzymes.
Topics: Animals; Antigens, Differentiation; CD57 Antigens; Chondroitin; Decapodiformes; Endopeptidases; Enzyme-Linked Immunosorbent Assay; Epitopes; Glucuronates; Glutamates; Glutamic Acid; Glycine; Microbial Collagenase; Oligosaccharides; Proteoglycans; Serine; Skin | 1991 |
Negative and positive cis-acting elements in the promoter of the mouse gene that encodes the serine/glycine-rich peptide core of secretory granule proteoglycans.
Topics: 3T3 Cells; Aggrecans; Animals; Base Sequence; Cytoplasmic Granules; DNA; Enhancer Elements, Genetic; Extracellular Matrix Proteins; Glycine; Glycoproteins; Growth Hormone; Lectins, C-Type; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Promoter Regions, Genetic; Proteoglycans; Rats; Rats, Inbred F344; Serine; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1992 |
Relationships among serine hydrolases: evidence for a common structural motif in triacylglyceride lipases and esterases.
Topics: Amino Acid Sequence; Esterases; Glycine; Lipase; Molecular Sequence Data; Molecular Structure; Mucorales; Oligopeptides; Protein Conformation; Serine; Serine Endopeptidases; X-Ray Diffraction | 1991 |
Mutations in Ser174 and the glycine-rich sequence (Gly149, Gly150, and Thr156) in the beta subunit of Escherichia coli H(+)-ATPase.
Topics: Amino Acid Sequence; Base Sequence; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Cloning, Molecular; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glycine; Molecular Sequence Data; Mutation; Operon; Proton-Translocating ATPases; Sequence Alignment; Serine | 1991 |
Glycine turnover and oxidation and hepatic serine synthesis from glycine in fetal lambs.
Topics: Animals; Carbon Isotopes; Carbon Radioisotopes; Female; Fetal Blood; Fetus; Glycine; Isotope Labeling; Kinetics; Liver; Oxidation-Reduction; Pregnancy; Radioisotope Dilution Technique; Serine; Sheep | 1991 |
Aminoaciduria as a marker of acute renal transplant rejection--a patient study.
Topics: Adolescent; Alanine; Amino Acids; Child; Child, Preschool; Creatinine; Female; Glycine; Graft Rejection; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Serine; Threonine | 1991 |
Low basal transcription of genes for tissue-specific collagens by fibroblasts and lymphoblastoid cells. Application to the characterization of a glycine 997 to serine substitution in alpha 1(II) collagen chains of a patient with spondyloepiphyseal dysplas
Topics: Base Sequence; Cells, Cultured; Collagen; DNA; Fibroblasts; Glycine; Heterozygote; Humans; Lymphocytes; Molecular Sequence Data; Mutation; Nucleic Acid Heteroduplexes; Nucleic Acid Hybridization; Osteochondrodysplasias; Phenotype; Polymerase Chain Reaction; Restriction Mapping; RNA Splicing; RNA, Messenger; Serine; Transcription, Genetic | 1991 |
Catalytic triad residue mutation (Asp156----Gly) causing familial lipoprotein lipase deficiency. Co-inheritance with a nonsense mutation (Ser447----Ter) in a Turkish family.
Topics: Adipose Tissue; Alleles; Aspartic Acid; Base Sequence; Catalysis; DNA; Glycine; Humans; Hyperlipoproteinemia Type I; Male; Molecular Sequence Data; Mutation; Nucleic Acid Hybridization; Pedigree; Polymerase Chain Reaction; RNA, Messenger; Serine; Turkey | 1991 |
Perilymphatic fistula: analysis of free amino acids in middle ear microaspirates.
Topics: Alanine; Amino Acids; Chromatography, High Pressure Liquid; Ear, Middle; Erythrocytes; Fistula; Glutamine; Glycine; Humans; Labyrinth Diseases; Methionine; Perilymph; Serine | 1991 |
Secondary structure and side-chain 1H and 13C resonance assignments of calmodulin in solution by heteronuclear multidimensional NMR spectroscopy.
Topics: Alanine; Amino Acid Sequence; Amino Acids, Branched-Chain; Amino Acids, Diamino; Amino Acids, Dicarboxylic; Animals; Asparagine; Binding Sites; Calcium; Calmodulin; Drosophila melanogaster; Glutamine; Glycine; Hydrogen Bonding; Leucine; Magnetic Resonance Spectroscopy; Methionine; Molecular Sequence Data; Molecular Structure; Proline; Recombinant Proteins; Serine; Solutions; Threonine | 1991 |
Glycine, glycinamide and D-serine act as positive modulators of signal transduction at the N-methyl-D-aspartate (NMDA) receptor in vivo: differential effects on mouse cerebellar cyclic guanosine monophosphate levels.
Topics: Animals; Cerebellum; Cerebral Ventricles; Cyclic GMP; Dose-Response Relationship, Drug; Glycine; Injections, Intraventricular; Isomerism; Male; Mice; Phencyclidine; Pyrrolidinones; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction | 1990 |
High-performance liquid chromatographic determination of selected amino acids in rat brain by precolumn derivatization with phenylisothiocyanate.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Isothiocyanates; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Thiocyanates | 1990 |
A glycine to serine polymorphism in the C-propeptide of the human type II procollagen.
Topics: Base Sequence; Female; Glycine; Humans; Male; Molecular Sequence Data; Pedigree; Peptide Fragments; Polymorphism, Restriction Fragment Length; Procollagen; Serine | 1990 |
The glycine site modulates NMDA-mediated changes of intracellular free calcium in cultures of hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cells, Cultured; Embryo, Mammalian; Glycine; Hippocampus; Ketamine; Kinetics; Kynurenic Acid; Macromolecular Substances; N-Methylaspartate; Neurons; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine | 1990 |
Renal arginine synthesis: studies in vitro and in vivo.
Topics: Alanine; Ammonium Chloride; Animals; Arginine; Aspartic Acid; Citrulline; Glomerular Filtration Rate; Glutamates; Glutamic Acid; Glutamine; Glycine; In Vitro Techniques; Kidney Cortex; Kidney Tubules; Kinetics; Male; Rats; Rats, Inbred Strains; Serine | 1990 |
6,7-Dinitroquinoxaline-2,3-dione and 6-nitro,7-cyanoquinoxaline-2,3-dione antagonize responses mediated by N-methyl-D-aspartate and NMDA-associated glycine recognition sites in vivo: measurements of cerebellar cyclic-GMP.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebellum; Cyclic AMP; Glycine; Harmaline; Kinetics; Male; Mice; N-Methylaspartate; Pyrrolidinones; Quinoxalines; Quisqualic Acid; Serine | 1990 |
Disruption of thymidylate synthesis and glycine-serine interconversion by L-methionine and L-homocystine in Raji cells.
Topics: Amino Acids; Burkitt Lymphoma; Glycine; Glycine Hydroxymethyltransferase; Homocystine; Humans; Methionine; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Tetrahydrofolates; Thymidine Monophosphate; Thymidylate Synthase; Thymine Nucleotides; Tumor Cells, Cultured | 1990 |
Role of glycine in the N-methyl-D-aspartate-mediated neuronal cytotoxicity.
Topics: Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Glycine; Kynurenic Acid; N-Methylaspartate; Neurons; Piperazines; Pyrrolidinones; Serine | 1990 |
Two-dimensional NMR studies of staphylococcal nuclease. 1. Sequence-specific assignments of hydrogen-1 signals and solution structure of the nuclease H124L-thymidine 3',5'-bisphosphate-Ca2+ ternary complex.
Topics: Alanine; Amino Acid Sequence; Calcium; Glycine; Isoleucine; Magnetic Resonance Spectroscopy; Micrococcal Nuclease; Molecular Sequence Data; Molecular Structure; Protein Conformation; Serine; Solutions; Threonine; Thymine Nucleotides; Valine | 1990 |
Immunolocalization of C1-tetrahydrofolate synthase in the rat kidney.
Topics: Aminohydrolases; Animals; Formate-Tetrahydrofolate Ligase; Glycine; Immunologic Techniques; Kidney Tubules; Kidney Tubules, Distal; Kidney Tubules, Proximal; Ligases; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Multienzyme Complexes; Oxidoreductases; Rats; Rats, Inbred Strains; Serine | 1990 |
Postnatal development of the glycine cleavage system in rat liver.
Topics: Aging; Amino Acids; Aminomethyltransferase; Animals; Animals, Newborn; Female; Glycine; Glycine Hydroxymethyltransferase; Hydroxymethyl and Formyl Transferases; Liver; Male; Mitochondria, Liver; Rats; Rats, Inbred Strains; Serine; Transferases | 1990 |
The role of a critical sulfhydryl group in the mechanism of serine hydroxymethyltransferase.
Topics: Dithionitrobenzoic Acid; Escherichia coli; Glycine; Glycine Hydroxymethyltransferase; Kinetics; Mutation; Serine; Structure-Activity Relationship; Sulfhydryl Compounds; Tetrahydrofolates; Transferases | 1990 |
Inhibition of GSH efflux from rat liver by methionine: effects of GSH synthesis in cells and perfused organ.
Topics: Alkynes; Amino Acids; Animals; Cells, Cultured; Cysteine; Glutathione; Glycine; Homocysteine; Kinetics; Liver; Male; Methionine; Pargyline; Perfusion; Rats; Rats, Inbred Strains; Serine | 1990 |
Regulation of the Escherichia coli glyA gene by the purR gene product.
Topics: Base Sequence; Binding Sites; Deoxyribonuclease I; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Bacterial; Glycine; Glycine Hydroxymethyltransferase; Molecular Sequence Data; Mutation; Plasmids; Repressor Proteins; Serine; Transcription Factors; Transduction, Genetic; Transferases | 1990 |
Methylthioadenosine serves as a single carbon source to the folate co-enzyme pool in rat bone marrow cells.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Bone Marrow; Carbon; Deoxyadenosines; Folic Acid; Formates; Glycine; Guanine; Male; Methionine; Methionine Adenosyltransferase; Oxidation-Reduction; Rats; Rats, Inbred Strains; Serine; Thionucleosides | 1990 |
Mutations that substitute serine for glycine alpha 1-598 and glycine alpha 1-631 in type I procollagen. The effects on thermal unfolding of the triple helix are position-specific and demonstrate that the protein unfolds through a series of cooperative blo
Topics: Base Sequence; Cells, Cultured; Codon; DNA; Fibroblasts; Glycine; Humans; Infant, Newborn; Infant, Premature; Male; Models, Structural; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Osteogenesis Imperfecta; Polymerase Chain Reaction; Procollagen; Protein Conformation; Protein Denaturation; Serine; Skin; Templates, Genetic | 1990 |
Role of the transsulfuration pathway and of gamma-cystathionase activity in the formation of cysteine and sulfate from methionine in rat hepatocytes.
Topics: Alkynes; Animals; Cystathionine gamma-Lyase; Cysteine; Glutathione; Glycine; Kinetics; Liver; Lyases; Male; Methionine; Pargyline; Rats; Rats, Inbred Strains; Serine; Sulfates; Sulfur Radioisotopes; Taurine | 1990 |
Glycine/serine ratio and the prenatal diagnosis of non-ketotic hyperglycinaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Amniotic Fluid; False Negative Reactions; Female; Glycine; Humans; Pregnancy; Pregnancy Trimester, Second; Prenatal Diagnosis; Serine | 1990 |
Abnormal serine hydroxymethyl transferase activity in the temporal lobes of schizophrenics.
Topics: Adult; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glycine; Glycine Hydroxymethyltransferase; Humans; Male; Middle Aged; Reference Values; Schizophrenia; Serine; Temporal Lobe | 1990 |
Glycine stimulates [3H]noradrenaline release by activating a strychnine-sensitive receptor present in rat hippocampus.
Topics: Animals; Bicuculline; Calcium; Glycine; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Potassium; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Serine; Strychnine; Synaptosomes; Tritium | 1990 |
Both agonists and antagonists of the strychnine-insensitive glycine site of N-methyl-D-aspartate receptors modulate polysynaptic excitations in slices of mouse olfactory cortex.
Topics: Action Potentials; Animals; Binding Sites; Glycine; Male; Mice; Olfactory Bulb; Perfusion; Picrotoxin; Receptors, N-Methyl-D-Aspartate; Serine; Strychnine; Synapses | 1990 |
The allosteric glycine site of the N-methyl-D-aspartate receptor modulates GABAergic-mediated synaptic events in neonatal rat CA3 hippocampal neurons.
Topics: Aging; Allosteric Regulation; Allosteric Site; Animals; Animals, Newborn; Aspartic Acid; Electric Conductivity; Female; gamma-Aminobutyric Acid; Glycine; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine; Synapses; Tetrodotoxin | 1990 |
[3H]D-serine labels strychnine-insensitive glycine recognition sites of rat central nervous system.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Glutamates; Glycine; Kinetics; Pons; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Glycine; Receptors, Neurotransmitter; Serine; Spinal Cord; Strychnine; Tritium | 1990 |
Neuropharmacological characterization of 1-aminocyclopropane-1-carboxylate and 1-aminocyclobutane-1-carboxylate, ligands of the N-methyl-D-aspartate-associated glycine receptor.
Topics: Amino Acids; Amino Acids, Cyclic; Animals; Biological Availability; Brain Chemistry; Gas Chromatography-Mass Spectrometry; Glycine; Half-Life; Injections, Intravenous; Injections, Intraventricular; Mice; Pyrrolidinones; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine | 1990 |
Amino acid transport in membrane vesicles of Clostridium thermoautotrophicum.
Topics: Alanine; Amino Acids; Biological Transport, Active; Cell Membrane; Clostridium; Glycine; Kinetics; Protons; Serine | 1990 |
Activation of the glycine site associated with the NMDA receptor is required for induction of LTP in neonatal hippocampus.
Topics: Animals; Animals, Newborn; Electric Stimulation; Electrophysiology; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine | 1990 |
Glyphosate catabolism by Pseudomonas sp. strain PG2982.
Topics: Adenine; Bacterial Proteins; Formaldehyde; Formates; Glycine; Glyphosate; Guanine; Methionine; Oxidoreductases, N-Demethylating; Pseudomonas; Sarcosine; Sarcosine Oxidase; Serine | 1986 |
Solid-state NMR studies of Klebsiella pneumoniae grown under nitrogen-fixing conditions.
Topics: Bacterial Proteins; Carbon; Glycine; Klebsiella pneumoniae; Magnetic Resonance Spectroscopy; Nitrogen; Purines; RNA, Bacterial; RNA, Ribosomal; Serine | 1987 |
Serum amino acid patterns and toxicity symptoms following the absorption of irrigant containing glycine in transurethral prostatic surgery.
Topics: Absorption; Aged; Aged, 80 and over; Amino Acids; Anesthesia, Epidural; Glycine; Humans; Male; Middle Aged; Prostatectomy; Prostatic Hyperplasia; Serine; Therapeutic Irrigation; Water-Electrolyte Balance | 1988 |
Serine synthesis by the rat kidney.
Topics: Animals; Glycine; In Vitro Techniques; Kidney; Rats; Sarcosine; Serine | 1988 |
Attenuation of 2-methoxyethanol-induced testicular toxicity in the rat by simple physiological compounds.
Topics: Animals; Drug Interactions; Ethylene Glycols; Glucose; Glycine; Male; Organ Size; Rats; Rats, Inbred F344; Sarcosine; Serine; Spermatogenesis; Testis | 1989 |
A single base mutation that substitutes serine for glycine 790 of the alpha 1 (III) chain of type III procollagen exposes an arginine and causes Ehlers-Danlos syndrome IV.
Topics: Arginine; Base Sequence; Codon; DNA; Ehlers-Danlos Syndrome; Glycine; Humans; Molecular Sequence Data; Procollagen; RNA, Messenger; Serine | 1989 |
Site-directed mutagenesis of the cysteinyl residues and the active-site serine residue of bacterial D-amino acid transaminase.
Topics: Bacillus; Base Sequence; Binding Sites; Cysteine; D-Alanine Transaminase; Dithionitrobenzoic Acid; Glycine; Kinetics; Macromolecular Substances; Molecular Sequence Data; Mutation; Serine; Transaminases | 1989 |
Characterization of interaction of active-site serine mutants of tissue-type plasminogen activator with plasminogen activator inhibitor-1.
Topics: Base Sequence; Binding Sites; Blotting, Western; DNA; Glycine; Glycoproteins; Humans; Molecular Sequence Data; Molecular Weight; Mutation; Oligonucleotide Probes; Plasminogen Activators; Plasminogen Inactivators; Serine; Threonine; Tissue Plasminogen Activator | 1989 |
G6PD mahidol, a common deficient variant in South East Asia is caused by a (163)glycine----serine mutation.
Topics: Asia, Southeastern; Base Sequence; Genes; Genetic Variation; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Glycine; Humans; Molecular Sequence Data; Mutation; Serine | 1989 |
Non-ketotic hyperglycinaemia: glycine/serine ratio in amniotic fluid--an unreliable method for prenatal diagnosis.
Topics: Amino Acid Metabolism, Inborn Errors; Amniotic Fluid; Female; Glycine; Humans; Pregnancy; Pregnancy Trimester, Second; Prenatal Diagnosis; Serine | 1989 |
Characteristics of acidic, basic and neutral amino acid transport in the perfused rat hindlimb.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Female; Glutamates; Glycine; Hindlimb; Insulin; Kinetics; Lysine; Methylhistidines; Proline; Rats; Rats, Inbred Strains; Sarcolemma; Serine; Sodium | 1989 |
Effect of 7-chloro kynurenic acid on glycine modulation of the N-methyl-D-aspartate response in guinea-pig myenteric plexus.
Topics: Animals; Aspartic Acid; Glycine; Guinea Pigs; In Vitro Techniques; Kynurenic Acid; Male; Myenteric Plexus; N-Methylaspartate; Serine | 1989 |
Substitution of serine for alpha 1(I)-glycine 844 in a severe variant of osteogenesis imperfecta minimally destabilizes the triple helix of type I procollagen. The effects of glycine substitutions on thermal stability are either position of amino acid spe
Topics: Cell Line; Cells, Cultured; Child, Preschool; Female; Fibroblasts; Gene Amplification; Genes; Genetic Variation; Glycine; Humans; Male; Mutation; Osteogenesis Imperfecta; Procollagen; Protein Conformation; Protein Denaturation; Restriction Mapping; Serine; Skin; Thermodynamics | 1989 |
Plasma amino acid concentrations in premature infants: effect of sampling site.
Topics: Alanine; Amino Acids; Aspartic Acid; Blood Specimen Collection; Capillaries; Chromatography, High Pressure Liquid; Glycine; Heel; Histidine; Humans; Infant, Newborn; Infant, Premature; Serine; Tryptophan; Veins | 1989 |
Renal serine production in vivo: effects of dietary manipulation of serine status.
Topics: Animals; Caseins; Diet; Glycine; Kidney; Male; Rats; Rats, Inbred Strains; Renal Circulation; Serine | 1989 |
Changes in the concentrations of hydroxyproline, glycine and serine in the plasma of haemodialysis patients undergoing erythropoietin therapy.
Topics: Adult; Aged; Anemia; Erythropoietin; Female; Follow-Up Studies; Glycine; Hemoglobins; Humans; Hydroxyproline; Male; Middle Aged; Parathyroid Hormone; Proline; Recombinant Proteins; Renal Dialysis; Serine | 1989 |
Effects of serine and glycine on proliferation of an Ishikawa cell variant.
Topics: Adenocarcinoma; Adult; Breast Neoplasms; Cell Division; Cell Line; DNA Replication; DNA, Neoplasm; Female; Genetic Variation; Glycine; Humans; Kinetics; Serine; Tumor Cells, Cultured | 1989 |
Molecular basis of adult-onset and chronic GM2 gangliosidoses in patients of Ashkenazi Jewish origin: substitution of serine for glycine at position 269 of the alpha-subunit of beta-hexosaminidase.
Topics: Adult; Base Sequence; beta-N-Acetylhexosaminidases; Cells, Cultured; Europe; Fibroblasts; G(M2) Ganglioside; Gangliosidoses; Glycine; Humans; Isoenzymes; Jews; Macromolecular Substances; Molecular Sequence Data; Mutation; Reference Values; Serine | 1989 |
Modulation of NMDA receptor-mediated responses by glycine and D-serine in the rat thalamus in vivo.
Topics: Action Potentials; Animals; Aspartic Acid; Glycine; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine; Strychnine; Thalamus | 1989 |
Glycine and D-serine act as positive modulators of signal transduction at N-methyl-D-aspartate sensitive glutamate receptors in cultured cerebellar granule cells.
Topics: Animals; Aspartic Acid; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebellum; Glycine; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Serine; Signal Transduction; Strychnine | 1989 |
Ontogeny of strychnine-insensitive [3H]glycine binding sites in rat forebrain.
Topics: Animals; Brain; Gestational Age; Glycine; Male; Medial Forebrain Bundle; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine; Strychnine | 1989 |
Effect of impact trauma on neurotransmitter and nonneurotransmitter amino acids in rat spinal cord.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kinetics; Laminectomy; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Serine; Spinal Cord; Spinal Cord Injuries; Taurine; Threonine | 1989 |
P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance.
Topics: Adrenal Glands; Alanine; Amino Acid Sequence; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Cell Line; Cloning, Molecular; DNA; Drug Resistance; Genetic Vectors; Glycine; Humans; Membrane Glycoproteins; Molecular Sequence Data; Polymorphism, Genetic; Serine; Tumor Cells, Cultured | 1989 |
Glycine to serine substitution in the triple helical domain of pro-alpha 1 (II) collagen results in a lethal perinatal form of short-limbed dwarfism.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Codon; Dwarfism; Glycine; Humans; Molecular Sequence Data; Mutation; Nucleic Acid Hybridization; Polymorphism, Restriction Fragment Length; Procollagen; Protein Conformation; Restriction Mapping; Serine | 1989 |
Ifenprodil and SL 82.0715 antagonize N-methyl-D-aspartate (NMDA)-coupled glycine receptor responses in vivo.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebellum; Cyclic GMP; Glycine; Injections; Male; Mice; Piperidines; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine; Time Factors | 1989 |
Substitution of amino acids in helix F of bacteriorhodopsin: effects on the photochemical cycle.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Bacteriorhodopsins; Glutamates; Glutamic Acid; Glutamine; Glycine; Hydrogen Bonding; Kinetics; Leucine; Molecular Sequence Data; Mutation; Phenylalanine; Photochemistry; Proline; Protons; Serine; Tryptophan | 1989 |
One-carbon metabolism in lectin-activated human lymphocytes.
Topics: Blood Proteins; Carbon; Cells, Cultured; Choline; DNA; Formates; Glycine; Histidine; Humans; Lymphocyte Activation; Lymphocytes; Methionine; Purine Nucleotides; Purines; Pyrimidine Nucleotides; Pyrimidines; RNA; Serine; Thymine; Tryptophan | 1985 |
Structural and functional analysis of a cloned segment of Escherichia coli DNA that specifies proteins of a C4 pathway of serine biosynthesis.
Topics: Alcohol Oxidoreductases; Bacterial Proteins; Chemical Phenomena; Chemistry; Cloning, Molecular; DNA Restriction Enzymes; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genes; Genes, Bacterial; Glycine; Mutation; Phenotype; Plasmids; Serine; Transcription, Genetic | 1987 |
Kynurenic acid antagonises responses to NMDA via an action at the strychnine-insensitive glycine receptor.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glycine; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, Neurotransmitter; Serine; Strychnine | 1988 |
Glycine and D-serine increase the affinity of N-methyl-D-aspartate sensitive glutamate binding sites in rat brain synaptic membranes.
Topics: Animals; Aspartic Acid; Brain; Glutamates; Glycine; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Serine; Synaptic Membranes | 1988 |
Splanchnic substrate balance in malnourished patients during parenteral nutrition.
Topics: Adipose Tissue; Alanine; Amino Acids, Branched-Chain; Cystine; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycine; Humans; Lipids; Liver; Male; Mesentery; Nitrogen; Parenteral Nutrition; Parenteral Nutrition, Total; Protein Biosynthesis; Protein-Energy Malnutrition; Serine; Splanchnic Circulation; Threonine; Tyrosine | 1985 |
Maternal undernutrition during lactation: effect on amino acids in brain regions of offspring.
Topics: Amino Acids; Animals; Aspartic Acid; Body Weight; Brain Chemistry; Corpus Striatum; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Hippocampus; Hypothalamus; Lactation; Nutrition Disorders; Pregnancy; Rats; Rats, Inbred Strains; Serine; Taurine | 1985 |
Regulation of glutamine synthesis by glycine and serine in Neurospora crassa.
Topics: Glutamate-Ammonia Ligase; Glutamine; Glycine; Mutation; Neurospora; Neurospora crassa; Serine | 1986 |
Isolation of serine, glutamic acid, and glycine-rich nonhistone proteins from bovine cerebral cortex.
Topics: Amino Acids; Animals; Cattle; Cerebral Cortex; Chromosomal Proteins, Non-Histone; Electrophoresis, Polyacrylamide Gel; Glutamates; Glutamic Acid; Glycine; Serine | 1985 |
Glutamic acid as a putative transmitter of the interhemispheric corticocortical connections in the rat.
Topics: Alanine; Animals; Aspartic Acid; Brain Chemistry; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Male; Rats; Rats, Inbred Strains; Serine; Threonine | 1986 |
Renal metabolism of amino acids in vivo: studies on serine and glycine fluxes.
Topics: Amino Acids; Animals; Blood Gas Analysis; Cysteamine; gamma-Glutamyltransferase; Glycine; Hemodynamics; Kidney; Male; Osmolar Concentration; Picolinic Acids; Rats; Rats, Inbred Strains; Renal Circulation; Serine | 1987 |
Huntington's disease: studies on brain free amino acids.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Aspartic Acid; Brain; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Histidine; Humans; Huntington Disease; Lysine; Male; Middle Aged; Putamen; Serine; Taurine | 1988 |
Yeast cytochrome c with phenylalanine or tyrosine at position 87 transfers electrons to (zinc cytochrome c peroxidase)+ at a rate ten thousand times that of the serine-87 or glycine-87 variants.
Topics: Cytochrome c Group; Cytochrome-c Peroxidase; Electron Transport; Genetic Variation; Glycine; History, Ancient; Mutation; Peroxidases; Phenylalanine; Saccharomyces cerevisiae; Serine; Structure-Activity Relationship; Tyrosine | 1987 |
Concentrations of glycine and serine in cerebrospinal fluid during disturbed consciousness; a study of the therapeutic effect of thyrotropin-releasing hormone on the consciousness level.
Topics: Adolescent; Adult; Aged; Amino Acids; Cognition Disorders; Consciousness Disorders; Female; Glycine; Humans; Male; Middle Aged; Serine; Thyrotropin-Releasing Hormone | 1986 |
Serine synthesis in rat kidney: studies with perfused kidney and cortical tubules.
Topics: Animals; Gluconeogenesis; Glucose; Glycine; Glycolysis; Kidney; Kidney Cortex; Kidney Tubules; Male; Rats; Serine; Subcellular Fractions; Time Factors | 1986 |
Direct observation of tryptophan biosynthesis in Escherichia coli by carbon-13 nuclear magnetic resonance spectroscopy.
Topics: Carbon Isotopes; Escherichia coli; Glucose; Glycine; Magnetic Resonance Spectroscopy; Serine; Tryptophan | 1986 |
Serine, glycine and carbohydrates in schizoaffective disorders.
Topics: Amino Acids; Dietary Carbohydrates; Glycine; Humans; Psychotic Disorders; Reference Values; Serine | 1986 |
Endogenously formed norharman (beta-carboline) in platelet rich plasma obtained from porphyric rats.
Topics: Alkaloids; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Blood Platelets; Carbolines; Catalepsy; Glycine; Harmine; Male; Porphobilinogen; Porphyrias; Rats; Rats, Inbred Strains; Serine | 1986 |
Significance of transported glycine in the conjugation of sodium benzoate in spf mutant mice with ornithine transcarbamylase deficiency.
Topics: Animals; Benzoates; Benzoic Acid; Carbon Radioisotopes; Glycine; Kinetics; Liver; Mice; Mice, Mutant Strains; Mutation; Ornithine Carbamoyltransferase Deficiency Disease; Serine; Species Specificity; Tritium | 1986 |
Concentrations of GABA and glycine in discrete brain nuclei. Stress-induced changes in the levels of inhibitory amino acids.
Topics: Animals; Brain Chemistry; gamma-Aminobutyric Acid; Glycine; Male; Postmortem Changes; Rats; Rats, Inbred Strains; Serine | 1986 |
The biochemical basis for the distinction between the two Cryptococcus neoformans varieties with CGB medium.
Topics: Biological Transport; Bromthymol Blue; Canavanine; Cryptococcus; Cryptococcus neoformans; Culture Media; Glycine; Pyruvates; Pyruvic Acid; Serine | 1986 |
Mechanism of the glycine cleavage reaction: retention of C-2 hydrogens of glycine on the intermediate attached to H-protein and evidence for the inability of serine hydroxymethyltransferase to catalyze the glycine decarboxylation.
Topics: Amino Acid Oxidoreductases; Aminomethyltransferase; Animals; Carrier Proteins; Cattle; Chickens; Cytosol; Decarboxylation; Glycine; Glycine Decarboxylase Complex H-Protein; Glycine Dehydrogenase (Decarboxylating); Glycine Hydroxymethyltransferase; Hydrogen; Hydroxymethyl and Formyl Transferases; Liver; Multienzyme Complexes; Serine; Transferases | 1986 |
Rickettsia prowazekii requires host cell serine and glycine for growth.
Topics: Amino Acids; Animals; Glycine; L Cells; Rickettsia prowazekii; Serine; Vero Cells | 1987 |
Solid-state NMR studies of regulation of N-(phosphonomethyl)glycine and glycine metabolism in Pseudomonas sp. strain PG2982.
Topics: Ammonia; Carbon; Glycine; Glyphosate; Magnetic Resonance Spectroscopy; Nitrogen; Pseudomonas; Pyruvates; Pyruvic Acid; Serine | 1987 |
Homocysteinemia: depressed plasma serine levels.
Topics: Adult; Betaine; Carbon-Oxygen Lyases; Child, Preschool; Folic Acid; Glycine; Homocysteine; Humans; Isoleucine; Kidney Transplantation; Lyases; Male; Serine | 1987 |
Oxygen limitation on L-serine production in a hollow-fiber bioreactor.
Topics: Glycine; Kinetics; Methanol; Methods; Oxygen Consumption; Pseudomonas; Serine; Ultrafiltration | 1986 |
L-proline uptake in human fibroblasts: evidence for a high-affinity system in addition to system A.
Topics: Aminoisobutyric Acids; Biological Transport; Cells, Cultured; Fibroblasts; Glycine; Humans; Kinetics; Proline; Serine | 1987 |
An estimate of the extent of deamination of L-serine in auxotrophs of Escherichia coli K-12.
Topics: Culture Media; Escherichia coli; Glycine; L-Serine Dehydratase; Mutation; Serine | 1986 |
Glycine availability limits maximum hippurate synthesis in growing rats.
Topics: Animals; Benzoates; Benzoic Acid; Biological Availability; Dose-Response Relationship, Drug; Enzyme Induction; Glycine; Hippurates; Liver; Male; Osmolar Concentration; Rats; Rats, Inbred Strains; Serine | 1987 |
L-threo-3,4-dihydroxyphenylserine (DOPS) aldolase: a new enzyme cleaving DOPS into protocatechualdehyde and glycine.
Topics: Aldehyde Dehydrogenase; Aldehyde-Lyases; Benzaldehydes; Catechols; Cerebral Cortex; Droxidopa; Glycine; Humans; Serine; Subcellular Fractions; Substrate Specificity | 1987 |
Genetic characterization of a highly efficient alternate pathway of serine biosynthesis in Escherichia coli.
Topics: Alcohol Oxidoreductases; Culture Media; Escherichia coli; Glycine; Mutation; Phenotype; Serine; Threonine | 1987 |
Prenatal diagnosis of non-ketotic hyperglycinaemia:amniotic fluid glycine and glycine:serine ratios.
Topics: Amino Acid Metabolism, Inborn Errors; Amniotic Fluid; Female; Gestational Age; Glycine; Humans; Pregnancy; Prenatal Diagnosis; Serine | 1987 |
The partial amino acid sequence of bovine cartilage proteoglycan, deduced from a cDNA clone, contains numerous Ser-Gly sequences arranged in homologous repeats.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cartilage; Cattle; Cloning, Molecular; Dipeptides; DNA; Glycine; Proteoglycans; Serine | 1987 |
Non-ketotic hyperglycinaemia: prenatal diagnosis and detection of heterozygotes with glycine/serine ratios.
Topics: Amino Acid Metabolism, Inborn Errors; Female; Genetic Carrier Screening; Glycine; Humans; Infant, Newborn; Male; Pregnancy; Prenatal Diagnosis; Serine | 1987 |
Behavior of L-threonine-degrading enzymes during liver regeneration.
Topics: Alcohol Oxidoreductases; Animals; Glycine; Glycine Hydroxymethyltransferase; Hepatectomy; Kinetics; Liver; Liver Regeneration; Male; Rats; Rats, Inbred Strains; Serine; Threonine; Threonine Dehydratase; Turpentine | 1987 |
The effects of vitamin B-6 deficiency in chronically azotemic and sham-operated rats.
Topics: Alanine; Animals; Asparagine; Aspartate Aminotransferases; Chronic Disease; Creatinine; Erythrocytes; Glycine; Rats; Serine; Urea; Uremia; Vitamin B 6 Deficiency | 1987 |
Importance of the mitochondrial amino acid pool in the sensitivity of erythroid cells to chloramphenicol: role of glycine and serine.
Topics: Amino Acids; Animals; Cells, Cultured; Chloramphenicol; Erythrocytes; Female; Glycine; In Vitro Techniques; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Male; Mice; Mice, Inbred DBA; Mitochondria; Neoplasm Proteins; Rats; Serine | 1987 |
Substrate specificity of an acylaminopeptidase that catalyzes the cleavage of the blocked amino termini of peptides.
Topics: Alanine; Aminopeptidases; Dipeptides; Erythrocytes; Glycine; Humans; Methionine; Serine; Substrate Specificity; Valine | 1988 |
Single amino acid substitution between SHV-1 beta-lactamase and cefotaxime-hydrolyzing SHV-2 enzyme.
Topics: Amino Acid Sequence; beta-Lactamases; Cefotaxime; Escherichia coli; Glycine; Isoenzymes; Molecular Sequence Data; Serine | 1988 |
Characterization of a novel L-serine transport system in Escherichia coli.
Topics: Alanine; Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membrane; Culture Media; Escherichia coli; Glycine; Isoleucine; Kinetics; Potassium Cyanide; Serine; Threonine; Valine | 1988 |
Phorbol ester treatment increases the exocytic rate of the transferrin receptor recycling pathway independent of serine-24 phosphorylation.
Topics: Animals; Cell Line; Exocytosis; Glycine; Humans; Mutation; Phosphorylation; Receptors, Transferrin; Serine; Tetradecanoylphorbol Acetate; Transfection; Transferrin | 1988 |
Derangement of one-carbon metabolism in episodic schizoaffective psychoses.
Topics: Bipolar Disorder; Carbolines; Carbon; Glycine; Humans; Schizophrenia; Serine; Taurine | 1988 |
The interaction of aminogroups with pyrroloquinoline quinone as detected by the reduction of nitroblue tetrazolium.
Topics: Alanine; Animals; Cattle; Glycine; Histidine; Humans; Lysine; Nitroblue Tetrazolium; Oxidation-Reduction; PQQ Cofactor; Quinolines; Serine; Sheep; Swine; Tetrazolium Salts; Valine | 1988 |
Gluconeogenesis from glycine and serine in fasted normal and diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fasting; Gluconeogenesis; Glycine; Male; Rats; Rats, Inbred Strains; Serine | 1988 |
Clinical effects of serine medication in non-ketotic hyperglycinaemia due to deficiency of P-protein of the glycine cleavage complex.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acid Oxidoreductases; Glycine; Glycine Dehydrogenase (Decarboxylating); Humans; Infant, Newborn; Male; Serine | 1988 |
Yeast mutants temperature-sensitive for growth after random mutagenesis of the chromosomal RAS2 gene and deletion of the RAS1 gene.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Base Sequence; Carbon; Chromosome Deletion; Cloning, Molecular; Culture Media; DNA, Fungal; Fungal Proteins; Galactose; Genes, ras; Glucose; Glycine; Immunoblotting; Molecular Sequence Data; Mutation; Phenotype; ras Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Temperature; Transformation, Genetic | 1988 |
In vivo oxidation of the methyl group of hepatic 5-methyltetrahydrofolate.
Topics: Adenosine; Animals; Betaine; Carbon Dioxide; Deoxyadenosines; Formyltetrahydrofolates; Glycine; Liver; Male; Methionine; Oxidation-Reduction; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Serine; Tetrahydrofolates; Thionucleosides; Time Factors | 1988 |
Metabolism of an ingested serine load in psychotic and nonpsychotic subjects.
Topics: Age Factors; Glycine; Glycine Hydroxymethyltransferase; Humans; Leucine; Metabolic Clearance Rate; Psychotic Disorders; Serine; Sex Factors; Transferases | 1985 |
A mutation in Escherichia coli K-12 results in a requirement for thiamine and a decrease in L-serine deaminase activity.
Topics: beta-Galactosidase; Drug Resistance, Microbial; Escherichia coli; Glycine; L-Serine Dehydratase; Leucine; Pyruvates; Pyruvic Acid; Serine; Thiamine; Transduction, Genetic | 1985 |
Comparison of glycine metabolism in mouse lymphoma cells either sensitive or resistant to L-asparaginase.
Topics: Animals; Asparaginase; Asparagine; Chromatography, High Pressure Liquid; Drug Resistance; Glycine; Glyoxylates; Leukemia L5178; Leukemia, Experimental; Mice; Serine | 1985 |
The effects of estradiol and triiodothyronine on protein synthesis by hepatocytes of juvenile coho salmon (Oncorhynchus kisutch).
Topics: Animals; Chemical Precipitation; Cycloleucine; Estradiol; Female; Glycine; Kinetics; Liver; Male; Protein Biosynthesis; Salmon; Serine; Triiodothyronine | 1985 |
Amino acid metabolism in euryhaline bivalves: regulation of glycine accumulation in ribbed mussel gills.
Topics: Amino Acids; Animals; Bivalvia; Chemical Fractionation; Gills; Glycine; Mitochondria; Oxidation-Reduction; Serine | 1985 |
Structural effects of substitutions on the p21 proteins.
Topics: Amino Acid Sequence; Glycine; Humans; Lysine; Models, Molecular; Neoplasm Proteins; Proline; Protein Conformation; Proto-Oncogene Proteins p21(ras); Serine; Structure-Activity Relationship; Valine | 1985 |
Kidney independent serine synthesis in the rat. Effect of dietary serine and glycine restriction.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Citrates; Citric Acid; Female; Glycine; Hydroxybutyrates; Ketoglutaric Acids; Kidney; Lactates; Male; Nephrectomy; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Serine | 1985 |
Glycine transport in mouse eggs and preimplantation embryos.
Topics: Alanine; Animals; Biological Transport; Blastocyst; Carbon; Cells, Cultured; Energy Metabolism; Female; Glycine; Mice; Oocytes; Serine; Sodium; Temperature | 1985 |
Antibodies specific for amino acid 12 of the ras oncogene product inhibit GTP binding.
Topics: Amino Acid Sequence; Antibodies; Cell Transformation, Neoplastic; Glycine; Guanosine Triphosphate; Humans; Kinetics; Neoplasm Proteins; Oncogenes; Phenotype; Proto-Oncogene Proteins p21(ras); Serine | 1985 |
Interconversion of serine and glycine is normal in psychotic patients.
Topics: Adult; Brain Chemistry; Glycine; Humans; Schizophrenia; Schizophrenia, Childhood; Serine | 1985 |
Hydroxyproline metabolism by the rat kidney: distribution of renal enzymes of hydroxyproline catabolism and renal conversion of hydroxyproline to glycine and serine.
Topics: Alanine Transaminase; Animals; Glycine; Hydroxyproline; Kidney; Kidney Cortex; Kidney Tubules; Male; Oxidoreductases Acting on CH-NH Group Donors; Oxo-Acid-Lyases; Perfusion; Rats; Rats, Inbred Strains; Serine; Transaminases | 1985 |
Folic acid responsive postmenopausal homocysteinemia.
Topics: Adult; Aging; Cystine; Dipeptides; Fasting; Female; Folic Acid; Glycine; Homocysteine; Humans; Male; Menopause; Methionine; Middle Aged; Serine | 1985 |
Different metabolic fate of two carbons of glycolate in its conversion to serine in Euglena gracilis z.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Euglena gracilis; Formate-Tetrahydrofolate Ligase; Glycine; Glycine Hydroxymethyltransferase; Glycolates; Kinetics; Serine | 1985 |
Characteristics of alanine: glyoxylate aminotransferase from Saccharomyces cerevisiae, a regulatory enzyme in the glyoxylate pathway of glycine and serine biosynthesis from tricarboxylic acid-cycle intermediates.
Topics: Alanine Transaminase; Amino Acids; Citric Acid Cycle; Electrophoresis, Polyacrylamide Gel; Glycine; Saccharomyces cerevisiae; Serine; Spectrophotometry; Substrate Specificity; Transaminases | 1985 |
Pathways of serine synthesis in the rat kidney.
Topics: Animals; Glycine; Kidney; Male; Phosphorylation; Rats; Rats, Inbred Strains; Serine | 1985 |
Analysis of the factors and implications of an empirical method for estimating the stability of mutant human haemoglobins.
Topics: Amino Acid Sequence; Glycine; Hemoglobins; Humans; Macromolecular Substances; Monte Carlo Method; Mutation; Probability; Protein Conformation; Serine; Tryptophan; Tyrosine | 1985 |
The activation of Mg++-dependent ATPase by aspartic and glutamic acids.
Topics: Adenosine Triphosphatases; Alanine; Asparagine; Aspartic Acid; Cell Membrane; Cell Membrane Permeability; Depression, Chemical; Enzyme Activation; Erythrocytes; Glutamates; Glutamine; Glycine; Humans; In Vitro Techniques; Leucine; Magnesium; Potassium; Saponins; Serine; Sodium | 1970 |
[Genetic polymorphism in the constant part of human immunoglobin lambda type L-chains. II].
Topics: Amino Acids; Bence Jones Protein; Chemical Phenomena; Chemistry; gamma-Globulins; Glycine; Humans; Immunoglobulins; Polymorphism, Genetic; Serine | 1971 |
Glycine metabolism in rat liver mitochondria. V. Intramitochondrial localization of the reversible glycine cleavage system and serine hydroxymethyltransferase.
Topics: Animals; Digitalis Glycosides; Electron Transport Complex IV; Glycine; Indicators and Reagents; Liver; Malate Dehydrogenase; Male; Methyltransferases; Mitochondria, Liver; Phosphotransferases; Polycyclic Compounds; Rats; Serine; Subcellular Fractions | 1971 |
Significance of the glycine cleavage system in glycine and serine catabolism in avian liver.
Topics: Ammonium Chloride; Animals; Arylformamidase; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Chickens; Columbidae; Cycloserine; Cysteine; Enzyme Activation; Folic Acid; Glycine; Hydroxylamines; Hypoxanthines; L-Serine Dehydratase; Liver; Male; Mitochondria, Liver; NAD; NADP; Oxidoreductases; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Semicarbazides; Serine; Species Specificity; Subcellular Fractions; Transferases; Uric Acid | 1971 |
Heterogeneity of normal human immunoglobulin light chains. Nonallelic variation in the constant region of lambda chains.
Topics: Acetamides; Amino Acids; Autoanalysis; Bence Jones Protein; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cysteamine; Disulfides; Dithiothreitol; Fluoroacetates; gamma-Globulins; Glycine; Humans; Hydrazines; Immunoglobulin G; Immunoglobulins; Iodoacetates; Methods; Peptides; Polymorphism, Genetic; Protein Denaturation; Serine; Sulfides; Trypsin; Urea | 1971 |
In vitro studies on the kinetics, composition, and homology of bovine keratohyalin.
Topics: Acrylamides; Animals; Arginine; Autoradiography; Cattle; Cytoplasmic Granules; Electrophoresis; Glycine; Histidine; Hyalin; In Vitro Techniques; Kinetics; Protein Biosynthesis; Proteins; Puromycin; RNA; Serine; Skin; Tritium | 1972 |
[Biochemical aspects of the effect of L-dopa in patients with Parkinson's disease].
Topics: Cysteine; Cystine; Dihydroxyphenylalanine; Female; Glycine; Humans; Male; Methionine; Parkinson Disease; Serine; Threonine; Time Factors | 1972 |
Studies on the enzymes involved in the biosynthesis of cyclo-tris (N-2,3-dihydroxybenzoyl-L-seryl) in Escherichia coli: kinetic properties of the L-serine-activating enzyme.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Anti-Bacterial Agents; Drug Stability; Enzyme Induction; Escherichia coli; Ethylmaleimide; Glycine; Gramicidin; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Phosphates; Phosphorus Radioisotopes; Proline; Serine; Threonine; Time Factors; Tritium; Tyrosine | 1973 |
[Free amino acids of the hemolymph of Sphaeroma serratum (crustacea, isopoda)].
Topics: Amino Acids; Animals; Chromatography, Ion Exchange; Crustacea; Dialysis; Glycine; Hemolymph; Serine | 1973 |
Accumulation of neutral amino acids by Streptococcus faecalis. Energy coupling by a proton-motive force.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Biological Transport, Active; Carbon Radioisotopes; Carboxylic Acids; Cycloserine; Dicyclohexylcarbodiimide; Energy Metabolism; Enterococcus faecalis; Glycine; Glycolysis; Hydrogen-Ion Concentration; Kinetics; Membrane Potentials; Models, Biological; Mutation; Polycyclic Compounds; Potassium; Serine; Sodium; Threonine; Time Factors; Valinomycin | 1973 |
Effect of adenine nucleotides on the oxidation of methyl groups in liver mitochondria.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Carbon Dioxide; Dinitrophenols; Folic Acid; Formaldehyde; Formates; Glycine; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methylation; Mitochondria, Liver; Mitochondrial Swelling; NAD; NADP; Oxygen Consumption; Rats; Rotenone; Sarcosine; Semicarbazides; Serine | 1973 |
Comparative studies on glutamine, serine, and glycine metabolisms in ureotelic and uricotelic animals.
Topics: Ammonia; Animals; Carbon Dioxide; Carbon Isotopes; Chickens; Columbidae; Dietary Proteins; Glucose; Glutamate-Ammonia Ligase; Glutamates; Glutaminase; Glutamine; Glycine; Humans; L-Serine Dehydratase; Liver; Male; Pentosyltransferases; Quail; Rats; Serine; Transferases; Urea; Uric Acid | 1973 |
[Biosynthesis of sideramines in fungi. Stereo-specificity of the mevalonic acid dehydration (brief report)].
Topics: Amines; Fusarium; Glycine; Hydroxamic Acids; Iron Chelating Agents; Mevalonic Acid; Peptides; Serine; Tritium | 1972 |
Glutamate, GABA and the direct cortical response in the rat.
Topics: Aminobutyrates; Animals; Carbon Isotopes; Cortical Spreading Depression; Electric Stimulation; Electroencephalography; Evoked Potentials; Glutamates; Glycine; Neurotransmitter Agents; Rats; Serine; Tritium; Urea; Visual Cortex | 1973 |
Lysine transport in turtle ventricle. II. Effect of extracellular ions and ouabain on lysine fluxes.
Topics: Alanine; Animals; Arginine; Biological Transport; Carbon Radioisotopes; Choline; Cystine; Glycine; Heart; In Vitro Techniques; Inulin; Kinetics; Lysine; Myocardium; Ornithine; Ouabain; Potassium; Serine; Sodium; Time Factors; Tritium; Turtles | 1973 |
Interconversion of glycine and serine in a synaptosome fraction isolated from the spinal cord, medulla oblongata, telencephalon, and cerebellum of the rat.
Topics: Alanine; Animals; Aspartic Acid; Carbon Radioisotopes; Cerebellum; Female; Glutamates; Glutamine; Glycine; In Vitro Techniques; Medulla Oblongata; Neurotransmitter Agents; Rats; Serine; Spinal Cord; Synaptosomes; Telencephalon; Threonine | 1973 |
The effect of changes in external salinity on the non-protein nitrogenous constituents of parietal muscle from Agonus cataphractus.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Body Water; Ethionine; Fishes; Glutamates; Glutamine; Glycine; Lysine; Methionine; Muscles; Nitrogen; Osmolar Concentration; Potassium; Seawater; Serine; Sodium; Sodium Chloride; Taurine; Threonine | 1974 |
[Relation between gamma-aminobutyric acid and tyrosine metabolism and changes in the brain and liver amino acid content in intact and adrenalectomized rats].
Topics: Adrenal Glands; Adrenalectomy; Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine; Liver; Lysine; Male; Rats; Serine; Stimulation, Chemical; Threonine; Tyrosine | 1972 |
Free amino acids in the photoreceptor cells of the frog retina.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Dansyl Compounds; Fluorescence; gamma-Aminobutyric Acid; Glutamine; Glycine; Organ Specificity; Photoreceptor Cells; Rana temporaria; Retina; Serine; Taurine; Threonine; Tritium | 1974 |
Comparison of the amino acid sequences of the variable regions of light chains derived from two homogeneous rabbit anti-pneumococcal antibodies.
Topics: Aconitic Acid; Alanine; Amino Acid Sequence; Amino Acids; Animals; Antibodies, Bacterial; Asparagine; Aspartic Acid; Autoanalysis; Chromatography, Gel; Electrophoresis, Paper; Glutamates; Glycine; Hydrolysis; Immunoglobulin Fragments; Rabbits; Serine; Streptococcus pneumoniae; Threonine; Tyrosine; Valine | 1974 |
Studies in immunoglobulin chemistry. I. Reinvestigation of the C-terminal amino acids of 6.5S rabbit and human gamma-globulins.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; gamma-Globulins; Glycine; Humans; Hydrazines; In Vitro Techniques; Peptides; Rabbits; Serine; Species Specificity; Sulfonic Acids | 1966 |
[Report on a vitamin B 6 deficiency anemia].
Topics: Adult; Anemia, Sideroblastic; Folic Acid; Glycine; Humans; Male; Pyridoxine; Serine; Vitamin B 6 Deficiency | 1966 |
[Incorporation of glycine-1-14C into casein by the isolated mammary gland of the sheep].
Topics: Amino Acids; Animals; Carbon Dioxide; Carbon Isotopes; Caseins; Citrates; Female; Glycine; In Vitro Techniques; Lactation; Lactose; Mammary Glands, Animal; Perfusion; Pregnancy; Serine; Sheep | 1967 |
A blocked N-terminal residue in the light chain of rabbit immunoglobulin G.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Chromatography, Paper; Electrophoresis; gamma-Globulins; Glutamates; Glycine; Hydrogen-Ion Concentration; Leucine; Peptide Hydrolases; Rabbits; Serine; Threonine; Valine | 1968 |
[Formiate metabolism in the red blood cell].
Topics: Carbon Dioxide; Carbon Isotopes; Erythrocytes; Formates; Glutathione; Glycine; Histidine; Humans; Methylene Blue; NADP; Peroxidases; Peroxides; Reticulocytes; Serine | 1968 |
[Complete aminco acid sequence of Bence Jones portein Kern. A new subgroup of the immunoglobulin L-chains of lambda-type].
Topics: Amino Acid Sequence; Bence Jones Protein; Carboxypeptidases; Chromatography, Ion Exchange; gamma-Globulins; Glycine; Peptides; Serine; Tyrosine | 1968 |
Argininosuccinic aciduria in hereditary hair diseases.
Topics: Adolescent; Adult; Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Chromatography, Paper; Cystinuria; Female; Glutamates; Glutamine; Glycine; Hair; Histidine; Humans; Infant; Lysine; Male; Middle Aged; Serine; Skin Diseases; Threonine; Tyrosine; Valine | 1968 |
Plasma and red blood cell amino acids of Egyptian children suffering from protein--calorie malnutrition.
Topics: Alanine; Amino Acids; Child, Preschool; Chromatography, Paper; Diet Therapy; Egypt; Erythrocytes; Follow-Up Studies; Glutamine; Glycine; Humans; Infant; Infant Nutrition Disorders; Isoleucine; Kwashiorkor; Leucine; Methionine; Protein-Energy Malnutrition; Serine; Valine | 1973 |
NH2-terminal amino acid distribution and amino acid composition of Streptococcus faecalis R soluble and ribosomal proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aspartic Acid; Autoanalysis; Bacterial Proteins; Cell-Free System; Culture Media; Dinitrophenols; Enterococcus faecalis; Folic Acid; Glutamates; Glycine; Methionine; Ribosomes; Serine; Solubility; Threonine | 1973 |
Characterization of degradation products of the cell wall released during growth and sporulation of Bacillus megaterium.
Topics: Alanine; Aspartic Acid; Bacillus megaterium; Carbon Radioisotopes; Cell Wall; Chromatography, Gel; Glucosamine; Glycine; Muramic Acids; Peptidoglycan; Phosphorus; Phosphorus Radioisotopes; Pimelic Acids; Serine; Spores, Bacterial; Time Factors | 1974 |
Active transport of D-alanine and related amino acids by whole cells of Bacillus subtilis.
Topics: Alanine; Amino Acids; Azides; Bacillus subtilis; Biological Transport, Active; Carbon Radioisotopes; Cycloserine; Depression, Chemical; Electron Transport; Glycine; Kinetics; Serine; Stereoisomerism | 1974 |
[The inducibility of aspartate-ammonium lyase of Pseudomonas fluorescence (type R)].
Topics: Alanine; Ammonia-Lyases; Aspartate Ammonia-Lyase; Aspartic Acid; Buffers; Chloramphenicol; Depression, Chemical; Dinitrophenols; Enzyme Induction; Glutamates; Glycine; Oxygen; Pseudomonas fluorescens; Serine; Stimulation, Chemical; Structure-Activity Relationship | 1974 |
The acid mucopolysaccharides in normal urine.
Topics: Chondroitin; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis; Glutamates; Glycine; Glycosaminoglycans; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Male; Peptides; Polysaccharides; Serine; Sulfates; Uronic Acids | 1967 |
The dermatan sulfate-protein linkage region.
Topics: Amino Acids; Chromatography, Paper; Galactose; Glycine; Glycosaminoglycans; Hexosamines; Humans; Peptides; Proteins; Serine; Umbilical Cord; Uronic Acids; Xylose | 1968 |
Properties of heparan sulphate and chondroitin sulphate from young and old human aortae.
Topics: Adolescent; Adult; Aged; Aging; Amino Acids; Aorta, Thoracic; Aspartic Acid; Chondroitin; Chromatography; Glutamates; Glycine; Glycosaminoglycans; Humans; Molecular Weight; Pyridinium Compounds; Serine; Sulfates | 1969 |
[Influence of changes in urinary pH on the excretion of amino acids from the isolated perfused rat kidney].
Topics: Alanine; Amino Acids; Animals; Arginine; Diffusion; Glycine; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Leucine; Lysine; Perfusion; Rats; Serine; Threonine; Tyrosine; Urine; Valine | 1967 |
Biosynthesis of the peptidoglycan of bacterial cell walls. 18. Purification and properties of L-alanyl transfer ribonucleic acid-uridine diphosphate-N-acetylmuramyl-pentapeptide transferase from Lactobacillus viridescens.
Topics: Alanine; Carbon Isotopes; Cell Wall; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Paper; Chromatography, Thin Layer; Cysteine; Electrophoresis; Electrophoresis, Disc; Glycine; Glycosaminoglycans; Hydrogen-Ion Concentration; Lactobacillus; Molecular Weight; Nickel; Oxidation-Reduction; RNA, Transfer; Serine; Transferases; Uracil Nucleotides | 1970 |
Biochemical studies of urinary acid mucopolysaccharide--peptide complexes in Hurler's syndrome.
Topics: Amino Acids; Aspartic Acid; Bone and Bones; Carbohydrate Metabolism, Inborn Errors; Child; Child, Preschool; Chondroitin; Chromatography, Ion Exchange; Female; Galactosamine; Glucosamine; Glutamates; Glycine; Glycosaminoglycans; Humans; Hypertrichosis; Joint Diseases; Male; Mucopolysaccharidosis I; Retinitis Pigmentosa; Serine; Uronic Acids | 1970 |
Effects of glycine and serine on serine hydroxymethyltransferase levels in logarithmic cultures of Neurospora crassa Wild type and Ser-1-mutant.
Topics: Formates; Glycine; Kinetics; Methionine; Mutation; Neurospora; Neurospora crassa; Serine; Tetrahydrofolates; Transferases | 1973 |
Some characteristics of the p-chlorophenylalanine-induced cataract.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Cataract; Chromatography, Gas; Crystallins; Electrophoresis; Female; Fenclonine; Glutathione; Glycine; Lens, Crystalline; Male; Ornithine; Rats; Serine; Threonine | 1973 |
Studies with a mathematical model of folate metabolism.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Floxuridine; Folic Acid; Formates; Glycine; Hydrolases; Kinetics; Leukemia L1210; Mathematics; Methotrexate; Models, Biological; Oxidoreductases; Pentosephosphates; Purines; Serine; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Thymidylate Synthase; Time Factors; Transferases | 1973 |
Serine biosynthesis in rat liver. Regulation of enzyme concentration by dietary factors.
Topics: Alcohol Oxidoreductases; Animals; Caseins; Cycloheximide; Cysteine; Dactinomycin; Dietary Proteins; Feedback; Glycerolphosphate Dehydrogenase; Glycine; Hydro-Lyases; In Vitro Techniques; Kinetics; Liver; Phosphoric Monoester Hydrolases; Rats; Serine | 1966 |
Structure of amino acyl oligonucleotides from T-1 ribonuclease digests of soluble ribonucleic acid charged with serine, glycine, threonine, and alanine.
Topics: Alanine; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Glycine; Phosphoric Monoester Hydrolases; Polynucleotides; Ribonucleases; RNA, Transfer; Serine; Spectrophotometry; Threonine; Venoms | 1966 |
The natural occurrence of a uracil-5-peptide and its metabolic relationship to guanosine-5'-monophosphate.
Topics: Arginine; Chromatography, Paper; Glycine; Guanine Nucleotides; In Vitro Techniques; Peptide Biosynthesis; Perchlorates; Plants, Edible; Proline; Seeds; Serine; Spectrophotometry; Uracil | 1966 |
On the possible involvement of charge transfer complexes (redox systems) in radioprotection.
Topics: Copper; Cysteine; Electron Spin Resonance Spectroscopy; Energy Transfer; Glutathione; Glycine; Oxidation-Reduction; Radiation Protection; Serine; Spectrum Analysis; Valine | 1967 |
[Use of amino acids and pathogenic and non-pathogenic E. coli with increased resistance to a number of antibiotics in experiments in vitro and in the process of treatment of patients with colienteritis].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Aspartic Acid; Child; Chloramphenicol; Chlortetracycline; Colistin; Drug Resistance, Microbial; Enteritis; Escherichia coli; Escherichia coli Infections; Glutamates; Glycine; Humans; In Vitro Techniques; Oxytetracycline; Proline; Serine; Streptomycin; Viomycin | 1967 |
Effect of protein intake on tissue amino acid levels and the enzymes of serine biosynthesis in the rat.
Topics: Alcohol Oxidoreductases; Amino Acids; Animals; Autoanalysis; Brain; Caseins; Cysteine; Cystine; Dietary Proteins; Glycine; Hydro-Lyases; Kidney; L-Serine Dehydratase; Liver; Male; Methionine; Phosphoric Monoester Hydrolases; Protein Deficiency; Rats; Serine; Taurine | 1968 |
The intraspinal distribution of some depressant amino acids.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain Chemistry; Cats; Depression, Chemical; Freezing; Glutamates; Glutamine; Glycine; Receptors, Drug; Serine; Spinal Cord; Spinal Nerves; Strychnine; Synapses; Synaptic Transmission; Taurine; Tissue Extracts | 1968 |
[A method for the detection of peptides separated by column chromatography: application to the analysis of collagen hydrolysates].
Topics: Amino Acids; Animals; Autoanalysis; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Collagen; Densitometry; Glycine; Indicators and Reagents; Methods; Microbial Collagenase; Peptides; Protein Hydrolysates; Rabbits; Serine; Skin; Temperature; Time Factors | 1968 |
Tetanus toxin and amino acid levels in cat spinal cord.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cats; Glycine; Injections; Serine; Spinal Cord; Synaptic Transmission; Tetanus Toxin | 1969 |
Glycine metabolism by rat liver mitochondria. 3. The glycine cleavage and the exchange of carboxyl carbon of glycine with bicarbonate.
Topics: Ammonia; Animals; Arsenic; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Folic Acid; Glycine; In Vitro Techniques; Kinetics; Mitochondria, Liver; NAD; Pyridoxal Phosphate; Rats; Serine; Sulfhydryl Compounds; Transferases | 1969 |
Amino acid uptake in isolated chick embryo heart cells.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Chick Embryo; Glycine; Heart; Histidine; In Vitro Techniques; Insulin; Leucine; Methionine; Microbial Collagenase; Myocardium; Oxygen Consumption; Proline; Protein Biosynthesis; Serine; Threonine | 1969 |
Glycine metabolism by rat liver mitochondria. IV. Isolation and characterization of hydrogen carrier protein, an essential factor for glycine metabolism.
Topics: Alcohols; Ammonia; Animals; Benzoates; Bicarbonates; Carbon Isotopes; Chromatography, DEAE-Cellulose; Chromatography, Gel; Drug Stability; Electron Transport; Electrophoresis, Disc; Ethylmaleimide; Glycine; Hydrogen; Hydrogen-Ion Concentration; Male; Methods; Mitochondria, Liver; Molecular Weight; NAD; Protein Binding; Proteins; Rats; Serine; Sulfur | 1969 |
[Formation of free radicals in aliphatic amino acids and peptides under conditions of photosensitization by dyes].
Topics: Acridines; Alanine; Amino Acids; Coloring Agents; Electron Spin Resonance Spectroscopy; Fluoresceins; Free Radicals; Glycine; Leucine; Peptides; Photosensitivity Disorders; Riboflavin; Serine; Solutions | 1966 |
Glycylhydroxyprolyl sequences in earthworm cuticle collagen: glycylhydroxyprolylserine.
Topics: Amino Acids; Animals; Annelida; Chromatography; Chromatography, Ion Exchange; Chromatography, Thin Layer; Collagen; Glycine; Hydroxyproline; Microbial Collagenase; Peptides; Protein Denaturation; Serine | 1970 |
RNA synthesis in cells infected with herpes simplex virus. 3. Absence of virus-specified arginyl- and seryl-tRNA in infected HEp-2 cells.
Topics: Arginine; Carcinoma; Cell Line; Chromatography; Chromatography, Gel; Culture Techniques; DNA, Viral; Glycine; Humans; Hybridization, Genetic; Hydrogen-Ion Concentration; Laryngeal Neoplasms; Ligases; Nucleic Acid Denaturation; Ribosomes; RNA; RNA, Transfer; Serine; Simplexvirus; Tritium; Uridine | 1970 |
Isolation of amino acid acceptor RNA from purified avian myeloblastosis virus.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Avian Leukosis Virus; Centrifugation, Density Gradient; Chick Embryo; Glycine; In Vitro Techniques; Isoleucine; Ligases; Methionine; Phenylalanine; Proline; Ribonucleases; RNA, Transfer; RNA, Viral; Serine; Threonine; Tritium; Tyrosine; Valine | 1970 |
The extracellular nuclease activity of Micrococcus sodonensis. IV. Physical studies, characterization as a glycoprotein and involvement with the cell wall.
Topics: Amino Acids; Animals; Cell Wall; Chromatography, Paper; Galactose; Glucosamine; Glucose; Glycine; Glycoproteins; Immunodiffusion; Micrococcus; Molecular Weight; Phosphoric Monoester Hydrolases; Proline; Rabbits; Rhamnose; Ribonucleases; Serine; Threonine; Time Factors; Tryptophan; Ultracentrifugation | 1970 |
Regulation of the transport and metabolism of amino acids in isolated fat cells. Effect of insulin and a possible role for adenosine 3',5'-monophosphate.
Topics: Adenine Nucleotides; Adipose Tissue; Adrenocorticotropic Hormone; Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Butyrates; Carbon Isotopes; Cyclic AMP; Cyclopentanes; Epididymis; Glucose; Glycine; Hot Temperature; In Vitro Techniques; Insulin; Kinetics; Leucine; Male; Palmitic Acids; Protein Biosynthesis; Proteins; Puromycin; Rats; Serine; Sodium; Theophylline | 1970 |
Isolation and characterization of three phosphoamido-neomycins and their conversion into neomycin by Streptomyces fradiae.
Topics: Chromatography, Paper; Culture Media; Diphosphates; Glycine; Neomycin; Quaternary Ammonium Compounds; Serine; Streptomyces | 1970 |
Peptidyl-tRNA. XII. Behaviour of peptidyl-tRNA-Phe from Escherichia coli on methylated albumin silicic acid column.
Topics: Alanine; Albumins; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography; Electrophoresis; Escherichia coli; Glycine; Peptides; Phenylalanine; RNA, Transfer; Serine; Silicon Dioxide | 1971 |
Control of serine biosynthesis in Micrococcus lysodeikticus: inhibition of phosphoglyceric acid dehydrogenase.
Topics: Adenine Nucleotides; Calcium; Carbon Isotopes; Cell-Free System; Edetic Acid; Glycerol; Glycerolphosphate Dehydrogenase; Glycerophosphates; Glycine; Magnesium; Manganese; Micrococcus; NAD; Quaternary Ammonium Compounds; Serine; Stereoisomerism; Sulfates; Zinc | 1971 |
The carbohydrate sequence of the glycopeptide chains of human transferrin.
Topics: Asparagine; Carbohydrates; Chromatography, DEAE-Cellulose; Chromatography, Gas; Chromatography, Gel; Disaccharides; Formaldehyde; Formates; Galactose; Galactosidases; Glycine; Glycopeptides; Glycoside Hydrolases; Humans; Hydrolysis; Mannose; Methylation; Neuraminic Acids; Periodic Acid; Serine; Threonine; Transferrin | 1971 |
[Physical and chemical characteristics and biosynthesis of myoalbumin of muscle tumors in rats].
Topics: Agar; Albumins; Amino Acids; Animals; Carbon Isotopes; Chromatography; Electrophoresis; Glycine; Muscle Proteins; Neoplasm Proteins; Neoplasms, Experimental; Neoplasms, Muscle Tissue; Rats; Serine | 1969 |
Photorespiration during C 4 photosynthesis.
Topics: Alanine; Alcohol Oxidoreductases; Aldehyde-Lyases; Aspartic Acid; Carbohydrates; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Chromatography, Ion Exchange; Electrophoresis; Folic Acid; Fructose; Glycerophosphates; Glycine; Glycolates; Glyoxylates; Hexosephosphates; Ligases; Malates; Oxidoreductases; Pentosephosphates; Phosphoric Monoester Hydrolases; Phosphotransferases; Photosynthesis; Plants; Pyruvates; Ribose; Serine; Sulfites; Transferases | 1971 |
Glycopeptides from silk fibroin of Bombyx mori.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Bombyx; Boron Compounds; Chromatography, Gel; Chromatography, Ion Exchange; Fibroins; Glucosamine; Glycine; Glycopeptides; Hydrolysis; Mannose; Molecular Weight; Oxidation-Reduction; Peptide Hydrolases; Peptides; Periodic Acid; Serine; Thiocyanates; Threonine; Trypsin | 1971 |
The biosynthesis of serine and glycine in Pseudomonas AM1 with special reference to growth on carbon sources other than C1 compounds.
Topics: Carbon; Culture Media; Ethanol; Glycine; Lactates; Methanol; Mutation; Phosphoric Monoester Hydrolases; Pseudomonas; Serine; Succinates; Transferases | 1971 |
Characterization of porcine malate dehydrogenase. I. An active center peptide.
Topics: Acetamides; Amino Acid Sequence; Animals; Binding Sites; Carbon Isotopes; Carboxypeptidases; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cysteine; Dansyl Compounds; Glycine; Histidine; Iodoacetates; Kinetics; Malate Dehydrogenase; Methionine; Mitochondria, Muscle; Myocardium; NAD; Peptides; Pronase; Serine; Swine; Threonine | 1971 |
Alterations of free amino acids concentrations in cat brain induced by rapid eye movement sleep deprivation.
Topics: Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Brain; Cats; Caudate Nucleus; Cysteine; Frontal Lobe; Glutamates; Glycine; Hippocampus; Histidine; Lysine; Male; Occipital Lobe; Reticular Formation; Serine; Sleep Deprivation; Sleep, REM; Thalamus; Threonine; Tyrosine | 1971 |
Genetic and physiological control of serine and glycine biosynthesis in Saccharomyces.
Topics: Acetates; Alanine; Ammonium Sulfate; Aspartic Acid; Carbon Isotopes; Cell-Free System; Chemical Precipitation; Chromatography, Paper; Culture Media; Fluorides; Genetics, Microbial; Glucose; Glutamates; Glycerolphosphate Dehydrogenase; Glycerophosphates; Glycine; Glycolysis; Glyoxylates; Isocitrates; Lyases; Mutation; NAD; Oxidative Phosphorylation; Saccharomyces; Serine; Spectrophotometry; Transferases | 1972 |
Glycolate metabolism in mesophyll cells and bundle sheath cells isolated from crabgrass, Digitaria sanguinalis (L.) Scop., leaves.
Topics: Alcohol Oxidoreductases; Amylases; Carbon Dioxide; Carboxy-Lyases; Catalase; Cells; Glycerophosphates; Glycine; Glycolates; Glyoxylates; Microscopy, Electron; Oxygen Consumption; Phosphoenolpyruvate; Phosphoric Acids; Phosphoric Monoester Hydrolases; Phosphotransferases; Plant Cells; Plants; Poaceae; Pyruvates; Serine; Transaminases; Transferases | 1972 |
The isolation of anionic phosphoproteins from bovine cortical bone via the periodate solubilization of bone collagen.
Topics: Amino Acids; Animals; Aspartic Acid; Bone and Bones; Calcification, Physiologic; Cattle; Chromatography, DEAE-Cellulose; Collagen; Electrophoresis, Disc; Galactosamine; Glutamates; Glycine; Hydroxylysine; Microbial Collagenase; Periodic Acid; Phosphoproteins; Phosphoric Acids; Pronase; Proteins; Serine; Solubility | 1972 |
The release of amino acids from the hemisected spinal cord during stimulation.
Topics: Amino Acids; Aminobutyrates; Animals; Anura; Aspartic Acid; Bufo bufo; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Electric Stimulation; Glutamates; Glycine; In Vitro Techniques; Leucine; Perfusion; Rana temporaria; Serine; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission; Threonine; Tritium | 1972 |
Glycine formation during growth of Pseudomonas AM1 on methanol and succinate.
Topics: Carbon Isotopes; Chromatography; Citric Acid Cycle; Glycine; Methanol; Phosphoric Monoester Hydrolases; Pseudomonas; Serine; Succinates | 1972 |
[Isoenzyme spectrum of serine transoxymethylase in the liver and in hepatomas].
Topics: Agar; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Electrophoresis; Gels; Glycine; Isoenzymes; Liver; Liver Neoplasms; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Proteins; Pyridoxal Phosphate; Rats; Serine; Spectrophotometry; Tetrahydrofolates; Transferases | 1973 |
The occurrence of a glycine cleavage system in mammalian brain.
Topics: Animals; Brain; Carbon Dioxide; Carbon Isotopes; Cats; Cattle; Digitonin; Dithiothreitol; Dogs; Enzyme Activation; Glycine; Male; Mitochondria; Multienzyme Complexes; NAD; Pyridoxal Phosphate; Rabbits; Rats; Serine; Subcellular Fractions; Swine; Tetrahydrofolates | 1973 |
Isolation and characterization of C1q, a subcomponent of the first component of complement, from human and rabbit sera.
Topics: Amino Acids; Animals; Aspartic Acid; Blood Protein Electrophoresis; Carbohydrates; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Complement System Proteins; Glutamates; Glycine; Hemolysis; Humans; Hydroxylysine; Hydroxyproline; Microbial Collagenase; Molecular Weight; Oxidation-Reduction; Rabbits; Serine; Ultracentrifugation | 1972 |
Folate deficiency in rats bearing the Walker tumor 256 and the Novikoff hepatoma.
Topics: Adenine; Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Choline; Diet; FIGLU Test; Folic Acid; Folic Acid Deficiency; Formates; Glycine; Guanine; Liver Neoplasms; Male; Methionine; Neoplasms, Experimental; Rats; Serine; Thymidine; Vitamin B 12 | 1973 |
N-terminal aspartate, glycine and serine in poliovirus capsid protein.
Topics: Amino Acid Sequence; Aspartic Acid; Centrifugation, Density Gradient; Chromatography, Thin Layer; Glycine; Hydrocarbons, Iodinated; Iodine Radioisotopes; Methods; Poliovirus; Serine; Thiocyanates; Viral Proteins | 1973 |
Phosphorylation of myelin basic protein by an adenosine 3':5'-cyclic monophosphate-dependent protein kinase.
Topics: Animals; Arginine; Cyclic AMP; Glycine; Leucine; Muscles; Myelin Sheath; Nerve Tissue Proteins; Protein Kinases; Rabbits; Serine | 1973 |
Biosynthesis of viomycin. I. Origin of alpha, beta-diaminopropionic acid and serine.
Topics: Acetates; Amino Acids, Diamino; Carbon Radioisotopes; Carbonates; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Culture Media; Formates; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Propionates; Serine; Sodium; Streptomyces; Viomycin | 1974 |
The metabolism of nitrilotriacetate by a pseudomonad.
Topics: Acetates; Alcohol Oxidoreductases; Amino Acids; Anaerobiosis; Carboxy-Lyases; Cell-Free System; Culture Media; Detergents; Dicarboxylic Acids; Glucose; Glyceric Acids; Glycine; Glyoxylates; Ligases; Magnesium; NAD; Nitrilotriacetic Acid; Oxaloacetates; Oxidation-Reduction; Oxygen; Pseudomonas; Pyruvates; Serine; Tetrahydrofolates; Thiamine Pyrophosphate; Transaminases; Transferases | 1973 |
Reversion of a Chinese hamster cell auxotrophic mutant.
Topics: Acid Phosphatase; Animals; Cell Fractionation; Cell Line; Cell Nucleus; Cricetinae; Cytosol; Electron Transport Complex IV; Female; Genes; Glycine; Hot Temperature; Mitochondria; Mutation; Ovary; Phenotype; Serine; Tetrahydrofolates; Transferases | 1974 |
Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. I. Effect of amino acid supply.
Topics: Amino Acids; Animals; Arginine; Asparagine; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Culture Media; Cycloheximide; Drug Synergism; Glutamine; Glycine; Immune Sera; Leucine; Liver Neoplasms; Neoplasm Proteins; Ornithine; Proline; Pyridoxal; Rats; Serine; Stimulation, Chemical; Time Factors | 1974 |
Effect of dorsal root section on amino acids of rat spinal cord.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Carbon Radioisotopes; Centrifugation, Density Gradient; Glutamates; Glutamine; Glycine; Lumbosacral Region; Lysine; Male; Mitochondria; Myelin Sheath; Nerve Degeneration; Nerve Endings; Nerve Tissue Proteins; Rats; Serine; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission; Tritium | 1974 |
Effect of glycine and serine in synthetic amino acid diets upon glycine and serine metabolism in chicks.
Topics: Alcohol Oxidoreductases; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Glyceric Acids; Glycine; Ketoglutaric Acids; Kidney; L-Serine Dehydratase; Liver; Organophosphorus Compounds; Phosphoric Monoester Hydrolases; Serine; Tetrahydrofolates; Transaminases; Transferases | 1974 |
Active transport of amino acids by membrane vesicles of Thiobacillus neapolitanus.
Topics: Amobarbital; Azides; Biological Transport, Active; Cell Membrane; Culture Media; Cyanides; Electron Transport; Glycine; Kinetics; Lactates; Leucine; NAD; Radioisotopes; Serine; Succinates; Thiobacillus; Thiosulfates; Threonine | 1974 |
Regulation of serine transhydroxymethylase activity in Salmonella typhimurium.
Topics: Adenine; Aspartic Acid; Cell-Free System; Enzyme Repression; Glucose; Glycine; Guanine; Inosine; Lyases; Methionine; Mutation; Phosphoric Monoester Hydrolases; Salmonella typhimurium; Serine; Spectrophotometry; Tetrahydrofolates; Thymine; Transferases; Trimethoprim; Vitamin B 12 | 1974 |
Growth of Pseudomonas C on C1 compounds: continuoous culture.
Topics: Aminobenzoates; Carbon Dioxide; Carbon Radioisotopes; Folic Acid; Formaldehyde; Formates; Glycine; Methanol; NAD; Polysorbates; Pseudomonas; Serine | 1974 |
Amino acids and cerebral excitability.
Topics: Amino Acids; Ammonia; Animals; Brain; Central Nervous System Stimulants; Diet; Glutamates; Glutamine; Glycine; Leucine; Lysine; Male; Methionine; Phenylalanine; Rats; Seizures; Serine; Stimulation, Chemical; Time Factors; Tryptophan; Valine | 1969 |
The oxidation of glycine by D-amino acid oxidase in extracts of mammalian central nervous tissue.
Topics: Alanine; Animals; Aspartic Acid; Benzoates; Carbon Isotopes; Cats; Central Nervous System; Cerebellum; Cerebral Cortex; D-Amino-Acid Oxidase; Glycine; Ketones; Mercury; Oxidation-Reduction; Pyrans; Serine; Spinal Cord; Tissue Extracts | 1969 |
Reactions of glycine synthesis and glycine cleavage catalyzed by extracts of Arthrobacter globiformis grown on glycine.
Topics: Ammonium Chloride; Arthrobacter; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Cell-Free System; Folic Acid; Formaldehyde; Glutathione; Glycine; Ion Exchange Resins; Kinetics; Mitochondria, Liver; NAD; NADP; Pyridoxal Phosphate; Serine; Sulfhydryl Compounds | 1969 |
[On the synthesis of serine peptides].
Topics: Amino Acid Sequence; Azides; Esters; Glycine; Peptides; Proline; Serine | 1969 |
[Synthetic polypeptides of the sequences (glycine-L-proline-L-serine)n and (glycine-L-serine-L-proline)].
Topics: Amino Acid Sequence; Antimetabolites; Chromatography, Gel; Cyclohexanes; Glycine; Imides; Molecular Weight; Peptides; Proline; Pyrrolidinones; Serine | 1969 |
Amino acid levels and enzyme activity in tissues of rats force-fed diets differing methionine content.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Aspartate Aminotransferases; Cystine; Diet; Eating; Glutamates; Glycine; Hydro-Lyases; Liver; Male; Methionine; Muscles; Nitrogen; Organ Size; Ornithine; Rats; Serine; Statistics as Topic; Threonine; Transferases; Tryptophan Oxygenase; Tyrosine Transaminase | 1969 |
Intracellular localization of enzymes in leaves and chloroplast membrane permeability to compounds involved in amino acid syntheses.
Topics: Alanine; Alcohol Oxidoreductases; Amino Acid Oxidoreductases; Amino Acids; Aspartate Aminotransferases; Aspartic Acid; Carbon Dioxide; Chloroplasts; Glutamate Dehydrogenase; Glutamates; Glutathione Reductase; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycine; Isocitrate Dehydrogenase; Malate Dehydrogenase; NAD; NADP; Nicotiana; Oxidoreductases; Plants; Plants, Edible; Plants, Toxic; Pyruvate Kinase; Serine | 1969 |
Convulsant activity of homocysteine and other short-chain mercaptoacids: protection therefrom.
Topics: Animals; Betaine; Central Nervous System Stimulants; Cysteine; Glycine; Homocysteine; Male; Methionine; Phenobarbital; Pyridoxine; Rats; Serine | 1969 |
Uptake of glycine and release of nucleoside-polyphosphates by Zooxanthellae.
Topics: Amino Acids; Animals; Carbon Dioxide; Carbon Isotopes; Chromatography; Cnidaria; Eukaryota; Glycine; Kinetics; Nucleotides; Phosphorus Isotopes; Rickettsiaceae; Serine | 1968 |
Characterization of ferredoxin from nutsedge, Cyperus rotundus L., and other species with a high photosynthetic capacity.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Bacteria; Biological Evolution; Carbon Dioxide; Chlorophyll; Chloroplasts; Cytochromes; Dicarboxylic Acids; Electron Spin Resonance Spectroscopy; Electrophoresis, Disc; Ferredoxins; Glycine; Hydrogen-Ion Concentration; Iron; Molecular Weight; NADP; Pentosephosphates; Peptides; Photochemistry; Photosynthesis; Plant Proteins; Plants; Serine; Species Specificity; Spectrophotometry; Sulfur | 1970 |
Major pathways of glycine and serine catabolism in rat liver.
Topics: Adenosine Triphosphate; Animals; Carbon Dioxide; Carbon Isotopes; Chromatography, Ion Exchange; Folic Acid; Glycine; L-Serine Dehydratase; Liver; Male; Mitochondria, Liver; NADP; Oxidoreductases; Pyruvates; Rats; Serine; Spectrophotometry; Transferases | 1970 |
Utilization of ammonium ions for purine precursor synthesis in soluble extracts of Ehrlich ascites cells.
Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Line; Cell-Free System; Deoxyribonucleotides; Diazooxonorleucine; Formates; Glucose; Glutamine; Glycine; Hydrogen-Ion Concentration; Mice; NADP; Neoplasms, Experimental; Nucleic Acids; Nucleotides; Protein Biosynthesis; Purines; Pyrimidines; Quaternary Ammonium Compounds; Ribonucleotides; Serine; Sodium | 1969 |
L-Threonine acetaldehyde-lyase in a strain of Bacillus subtilis.
Topics: Acetates; Aldehyde-Lyases; Bacillus subtilis; Carboxy-Lyases; Chromatography, Gel; Folic Acid; Glycine; Hydrazines; Hydrogen-Ion Concentration; Isoniazid; Kinetics; L-Serine Dehydratase; NAD; NADP; Phosphoric Acids; Pyridoxal Phosphate; Serine; Stereoisomerism; Threonine; Transferases | 1971 |
Absorption of some amino acids by the haemoflagellate, Trypanosoma gambiense.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Transport; Carbon Isotopes; Cysteine; Glutamates; Glycine; Iodoacetates; Kinetics; Leucine; Lysine; Ornithine; Rats; Serine; Threonine; Trypanosoma brucei gambiense | 1972 |
Rat liver glutamine synthetase. Preparation, properties, and mechanism of inhibition by carbamyl phosphate.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Animals; Binding Sites; Carbamates; Catalysis; Electrophoresis, Disc; Enzyme Activation; Glutamate-Ammonia Ligase; Glutamates; Glycine; Ketoglutaric Acids; Liver; Macromolecular Substances; Magnesium; Manganese; Methionine Sulfoximine; Molecular Weight; Phosphoric Acids; Protein Binding; Rats; Serine; Tritium; Ultracentrifugation | 1972 |
Carbon assimilation pathways during growth of Pseudomonas AM1 on methylamine and Pseudomonas MS on methylamine and trimethylsulphonium salts.
Topics: Alcohol Oxidoreductases; Alkanesulfonates; Aspartic Acid; Autoradiography; Carbon; Carbon Isotopes; Carboxy-Lyases; Chromatography; Fumarates; Glutamate-Ammonia Ligase; Glutamates; Glycine; Ligases; Malates; Methylamines; Methyltransferases; Pseudomonas; Serine; Succinates | 1972 |
Folic acid non-dependent formiminoglutamic aciduria in two siblings.
Topics: Administration, Oral; Adult; Amides; Child, Preschool; Chromatography, Ion Exchange; Creatinine; Electrophoresis, Paper; Female; FIGLU Test; Folic Acid; Follow-Up Studies; Formates; Glutamates; Glycine; Hemoglobins; Histidine; Humans; Imidazoles; Imines; Intelligence Tests; Male; Mass Spectrometry; Pedigree; Serine; Transferases | 1974 |
Mechanism of the reversible glycine cleavage reaction in Arthrobacter globiformis. I. Purification and function of protein components required for the reaction.
Topics: Arthrobacter; Bacterial Proteins; Bicarbonates; Carbon Radioisotopes; Chromatography, Gel; Decarboxylation; Disulfides; Electrophoresis, Disc; Glycine; Molecular Weight; Serine; Tritium | 1974 |
Preparation of some 2-phenylisopropyl-oxycarbonyl amino acids. Evaluation of their properties with particular reference to application in solid phase peptide synthesis.
Topics: Amino Acids; Bradykinin; Carbonates; Chromatography, Thin Layer; Dimethyl Sulfoxide; Glycine; Guanidines; Methods; Optical Rotation; Peptides; Phenylalanine; Proline; Serine; Time Factors | 1974 |
Report on the utilization of ethanolamine-1-14C by Mycobacterium 607.
Topics: Alanine; Carbon Radioisotopes; Chromatography, Paper; Ethanolamines; Glycine; Mycobacterium; Organophosphorus Compounds; Phosphatidylethanolamines; Serine | 1974 |
Feto-maternal amino acid metabolism.
Topics: Amino Acids; Amniocentesis; Amniotic Fluid; Arginine; Autoanalysis; Carnosine; Ethanolamines; Female; Fetus; Gestational Age; Glycine; Humans; Hydroxyproline; Infant, Newborn; Lysine; Maternal-Fetal Exchange; Phenylalanine; Pregnancy; Serine; Tyrosine; Umbilical Cord | 1974 |
Glycine-serine requirement for chicks.
Topics: Age Factors; Amino Acids; Animal Feed; Animals; Body Weight; Chickens; Female; Glucose; Glycine; Male; Nutritional Requirements; Serine | 1974 |
Plasma concentrations of tryptophan and other amino acids in manic-depressive patients.
Topics: Alanine; Arginine; Aspartic Acid; Bipolar Disorder; Emotions; Glutamates; Glycine; Humans; Isoleucine; Leucine; Methionine; Psychology; Serine; Threonine; Tryptophan; Tyrosine | 1974 |
[Amino acid levels in the blood serum of patients with chronic colitis].
Topics: Adult; Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Betaine; Chronic Disease; Citrulline; Colitis; Glutamates; Glutamine; Glycine; Histidine; Humans; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tryptophan; Tyrosine; Urea | 1974 |
Amino acid transport in human placental slices.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Biological Transport, Active; Carbon Radioisotopes; Chromatography, Paper; Extracellular Space; Female; Glutamates; Glycine; Humans; In Vitro Techniques; Kidney; Leucine; Lysine; Placenta; Pregnancy; Proline; Rats; Serine; Time Factors | 1974 |
Kinetic studies on the alkali-catalyzed hydrolysis and epimerization of model alkyl and hydroxyalkyl di- and tripeptides.
Topics: Alanine; Alcohols; Alkanes; Borates; Chemical Phenomena; Chemistry; Dipeptides; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Leucine; Oligopeptides; Optical Rotation; Phosphates; Serine; Stereoisomerism; Threonine | 1974 |
[Free amino acids in the 24 h urine of healthy children (author's transl)].
Topics: Adolescent; Age Factors; Alanine; Amino Acids; Aminobutyrates; Carnosine; Child; Chromatography, Ion Exchange; Citrulline; Female; Glycine; Histidine; Humans; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Serine; Sex Factors; Threonine; Tyrosine; Valine | 1974 |
The specific radioactivity of the tissue free amino acid pool as a basis for measuring the rate of protein synthesis in the rat in vivo.
Topics: Amino Acids; Animals; Brain; Carbon Radioisotopes; Chromatography, Ion Exchange; Diaphragm; Glycine; Infusions, Parenteral; Kidney; Kinetics; Leg; Liver; Muscles; Myocardium; Protein Biosynthesis; Rats; Serine | 1974 |
Free amino acids in the haemocytes and plasma of the larva of Calliphora vicina.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Blood Cells; Blood Coagulation; Diptera; Glutamates; Glutamine; Glycine; Hemolymph; Histidine; Isoleucine; Larva; Leucine; Lysine; Methionine; Phenylalanine; Plasma; Proline; Serine; Taurine; Threonine; Tyrosine; Valine | 1974 |
Inhibition of glycine-serine interconversion in cultured human fibroblasts by products of isoleucine catabolism.
Topics: Biotransformation; Carbon Radioisotopes; Cells, Cultured; Crotonates; Depression, Chemical; Fibroblasts; Glycine; Humans; Isoleucine; Serine; Tetrahydrofolates | 1974 |
Study of serum amino acids in Egyptian lead workers.
Topics: Adult; Alanine; Amino Acids; Colorimetry; Egypt; Glutamates; Glycine; Histidine; Humans; Lead Poisoning; Leucine; Lysine; Male; Middle Aged; Proline; Serine; Tyrosine; Valine | 1974 |
[Histocytosis-X. Histochemical and autoradiographic elements proving lipid synthesis in in vitro culture].
Topics: Acetates; Autoradiography; Carbon Radioisotopes; Cell Membrane; Choline; Culture Techniques; Eosinophilic Granuloma; Esterases; Fibroblasts; Glycerol; Glycine; Histiocytes; Histocytochemistry; Humans; Leucyl Aminopeptidase; Lipids; Lymphatic Diseases; Mevalonic Acid; Palmitates; Serine; Thymidine; Tritium; Uridine | 1974 |
Glycine metabolism by rat liver mitochondria. Isolation and some properties of the protein-bound intermediate of the reversible glycine cleavage reaction.
Topics: Animals; Bicarbonates; Carbon Radioisotopes; Chromatography, Gel; Ethylmaleimide; Glycine; Isotope Labeling; Mitochondria, Liver; Proteins; Rats; Serine; Tritium | 1974 |
[Effect of aminazine on the intensity of glycine conversion to serine and dicarboxylic amino acids in the brain and liver of rats].
Topics: Amino Acids, Dicarboxylic; Animals; Brain; Chlorpromazine; Depression, Chemical; Glycine; Liver; Rats; Serine; Time Factors | 1974 |
Characterization of human colonic mucoprotein antigen.
Topics: Amino Acids; Animals; Antigens; Carbohydrates; Carcinoembryonic Antigen; Colon; Fucose; Galactose; Glucosamine; Glutamates; Glycine; Humans; Immune Sera; Immunoelectrophoresis; Molecular Weight; Mucoproteins; Neuraminic Acids; Proline; Rabbits; Serine; Threonine | 1974 |
Prebiotic synthesis of hydrophobic and protein amino acids.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Ammonia; Aspartic Acid; Autoanalysis; Chromatography, Gas; Glutamates; Glycine; Isoleucine; Leucine; Mass Spectrometry; Methane; Nitrogen; Proline; Serine; Threonine; Valine; Water | 1972 |
Two amino-acid carriers in pea chloroplasts.
Topics: Alanine; Amino Acids; Biological Transport; Cell Membrane Permeability; Chloroplasts; Diffusion; Glycine; Osmolar Concentration; Osmosis; Plants; Serine; Sucrose | 1972 |
A sensitive double isotope derivative assay to measure release of amino acids from brain in vitro.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Asparagine; Carbon Isotopes; Cerebral Cortex; Dansyl Compounds; Electric Stimulation; Glutamates; Glycine; In Vitro Techniques; Isotope Labeling; Methods; Rats; Serine; Tritium; Valine | 1973 |
Tetanus toxin inhibits amino acid release from nerve endings in vitro.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Electric Stimulation; Glutamates; Glutamine; Glycine; In Vitro Techniques; Medulla Oblongata; Nerve Endings; Rats; Serine; Spinal Cord; Synaptic Vesicles; Synaptosomes; Tetanus Toxin | 1973 |
The role of amino acids as stimulants of antral release.
Topics: Acetylcholine; Alanine; Amino Acids; Animals; Choline; Cysteine; Dogs; Female; Gastric Fistula; Gastric Juice; Glycine; Histamine; Male; Pentagastrin; Phenylalanine; Pyloric Antrum; Secretory Rate; Serine; Stimulation, Chemical | 1974 |
Comparative study on major pathways of glycine and serine catabolism in vertebrate livers.
Topics: Aminohydrolases; Animals; Anura; Carbon Dioxide; Carbon Isotopes; Cattle; Chickens; Cyprinidae; Dogs; Glycine; Goats; Guinea Pigs; Humans; L-Serine Dehydratase; Male; Mitochondria, Liver; Proteins; Rabbits; Rana catesbeiana; Rats; Serine; Snakes; Transferases | 1972 |
Amino acid sequences in the -chains of adult bovine hemoglobins C-Rhodesia and D-Zambia.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Cattle; Chromatography, Ion Exchange; Chymotrypsin; Cyanogen Bromide; Electrophoresis, Starch Gel; Globins; Glutamine; Glycine; Hemoglobins, Abnormal; Lysine; Pepsin A; Peptides; Serine; Species Specificity; Thermolysin; Thiocyanates; Threonine; Trypsin; Ultracentrifugation; Zambia; Zimbabwe | 1972 |
Structure of a hypothalamic peptide possessing gonadotropin-releasing activity.
Topics: Amino Acid Sequence; Amino Acids; Animals; Arginine; Carbon Isotopes; Glutamates; Glycine; Gonadotropins; Histidine; Hypothalamus; Leucine; Mass Spectrometry; Peptide Chain Termination, Translational; Pituitary Hormone-Releasing Hormones; Proline; Serine; Swine; Tryptophan; Tyrosine | 1972 |
Production of staphylococcal -toxin in a defined medium and identification of a stimulating factor from yeast extract.
Topics: Amino Acids; Arginine; Chromatography, Thin Layer; Culture Media; Glycine; Hemolysis; Histidine; Saccharomyces cerevisiae; Serine; Staphylococcus; Stimulation, Chemical; Toxins, Biological | 1973 |
Synthesis and biological activities of analogs of luteinizing hormone-releasing hormone (LH-RH) substituted in position 1 or 2.
Topics: Animals; Castration; Female; Glutamates; Glycine; Leucine; Luteinizing Hormone; Ovary; Peptide Chain Elongation, Translational; Phenylalanine; Pituitary Hormone-Releasing Hormones; Proline; Rats; Serine; Structure-Activity Relationship | 1973 |
D-serine transport system in Escherichia coli K-12.
Topics: Alanine; Biological Transport, Active; Carbon Isotopes; Chromosome Mapping; Cycloserine; Drug Resistance, Microbial; Escherichia coli; Genes; Genetic Linkage; Glycine; L-Serine Dehydratase; Membrane Transport Proteins; Mutation; Recombination, Genetic; Serine; Stereoisomerism | 1973 |
The role of glycine in the biosynthesis of steroids.
Topics: Carbon Radioisotopes; Ergosterol; Glycine; Saccharomyces cerevisiae; Serine; Squalene; Vitamin D | 1973 |
Transport systems for alanine, serine, and glycine in Escherichia coli K-12.
Topics: Alanine; Autoradiography; Biological Transport, Active; Chromosome Mapping; Escherichia coli; Glycine; Leucine; Mutation; Serine; Stereoisomerism; Threonine; Transduction, Genetic | 1973 |
Synthesis of tRNA in cell-free extracts.
Topics: Cell-Free System; Coliphages; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glycine; Guanosine Triphosphate; Leucine; Lysogeny; Nucleotides; Phosphorus Radioisotopes; RNA, Transfer; RNA, Viral; Serine; Subcellular Fractions | 1973 |
Lack of growth hormone-releasing activity of (pyro)Glu-Ser-Gly-NH2.
Topics: Amino Acids; Animals; Biological Assay; Cattle; Chromatography, Thin Layer; Estradiol; Glycine; Growth Hormone; Growth Hormone-Releasing Hormone; Hypothalamus; Male; Oligopeptides; Pituitary Gland; Pyrrolidonecarboxylic Acid; Radioimmunoassay; Rats; Reserpine; Serine; Sheep; Time Factors | 1973 |
Amino acid replacements in proteins S5 and S12 of two Escherichia coli revertants from streptomycin dependence to independence.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Aspartic Acid; Bacterial Proteins; Chromatography; Chromatography, Gel; Chromatography, Paper; Escherichia coli; Glycine; Leucine; Mutation; Ribosomes; Serine; Streptomycin | 1973 |
Structural interactions between amino acid residues at positions 22 and 211 in the tryptophan synthetase alpha chain of Escherichia coli.
Topics: Amino Acids; Escherichia coli; Genes; Genetic Code; Glycine; Leucine; Mutation; Phenylalanine; Radiation Effects; Serine; Suppression, Genetic; Transduction, Genetic; Tryptophan Synthase; Ultraviolet Rays | 1974 |
The psu1+ amber suppressor gene of bacteriophage T4: identification of its amino acid and transfer RNA.
Topics: Alanine; Autoradiography; Carbon Isotopes; Coliphages; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genes; Genetic Code; Genetics, Microbial; Glycine; Mutation; Phenotype; Phenylalanine; Phosphorus Isotopes; RNA, Transfer; RNA, Viral; Serine; Sulfur Isotopes; Suppression, Genetic; Valine; Viral Proteins | 1973 |
[Why does the gastric mucosa secrete pepsins and hydrochloric acid? (author's transl)].
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Carbohydrate Metabolism; Cholecystokinin; Dogs; Feedback; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Glycine; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Lipid Metabolism; Pepsin A; Peptide Hydrolases; Peptides; Proteins; Sarcosine; Serine; Stimulation, Chemical; Time Factors; Transfer RNA Aminoacylation; Trypsin | 1974 |
Control of serine transhydroxymethylase synthesis in Escherichia coli K12.
Topics: Adenine; Culture Media; Escherichia coli; Formates; Glycine; Guanine; Histidine; Isoleucine; Methionine; Mutation; Serine; Thymidine; Transferases; Tritium; Valine | 1974 |
Regulation of one-carbon biosynthesis and utilization in Escherichia coli.
Topics: Adenine; Alcohol Oxidoreductases; Carbon Radioisotopes; Cell-Free System; Culture Media; Enzyme Repression; Escherichia coli; Formaldehyde; Glycine; Ligases; Methionine; Mutation; Nucleosides; Oxidoreductases; S-Adenosylmethionine; Serine; Spermidine; Tetrahydrofolates; Transferases | 1974 |
Evidence for the involvement of serine transhydroxymethylase in serine and glycine interconversions in Salmonella typhimurium.
Topics: Chromosome Mapping; Chromosomes, Bacterial; Glycine; Mutation; Phenotype; Recombination, Genetic; Salmonella typhimurium; Serine; Transduction, Genetic; Transferases | 1974 |
Nucleotide sequences of transfer ribonucleic acids.
Topics: Alanine; Arginine; Aspartic Acid; Base Sequence; Biological Evolution; Escherichia coli; Evaluation Studies as Topic; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Plants; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Serine; Species Specificity; Tryptophan; Tyrosine; Valine | 1974 |
Studies on T4-tRNA biosynthesis: accumulation of precursor tRNA molecules in a temperature sensitive mutant of Escherichia coli.
Topics: Base Sequence; Coliphages; Densitometry; Drug Stability; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glycine; Leucine; Mutation; Phosphorus Radioisotopes; Proline; Ribonucleases; Ribonucleotides; RNA, Transfer; RNA, Viral; Serine; Temperature; Time Factors; Transcription, Genetic; Virus Replication | 1974 |
The biochemical basis of the antimicrobial action of sulfonamides and trimethoprim in vivo--I. Action of sulfonamides and trimethoprim in blood and urine.
Topics: Amino Acids; Blood Bactericidal Activity; Culture Media; Drug Interactions; Escherichia coli; Folic Acid Antagonists; Glycine; Humans; Kinetics; Methionine; Purines; Serine; Sulfamethoxazole; Sulfonamides; Thymidine; Thymine; Time Factors; Trimethoprim | 1974 |
Carbamoylation of tRNA from yeast and rat liver.
Topics: Acylation; Amino Acids; Animals; Arginine; Carbamates; Carbon Radioisotopes; Glutamates; Glycine; Hydrolysis; Liver; Male; Rats; RNA, Transfer; Saccharomyces cerevisiae; Serine | 1972 |
Close correlation between changing content of specific amino acids in epileptogenic cortex of cats, and severity of epilepsy.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cats; Cerebral Cortex; Cobalt; Electroencephalography; Epilepsies, Partial; Epilepsy; Glutamates; Glutamine; Glycine; Motor Cortex; Serine; Taurine; Visual Cortex | 1972 |
Experimental protein-energy deficiency in rats. Ratio of serine+glycine to threonine as an index of deficiency.
Topics: Amino Acids; Animals; Blood Proteins; Body Weight; Chromatography; Diarrhea; Dietary Proteins; Edema; Feeding Behavior; Female; Glycine; Hair; Male; Protein Deficiency; Protein-Energy Malnutrition; Rats; Serine; Threonine | 1973 |
Plasma nonessential to essential amino acid ratio in marasmus.
Topics: Amino Acids; Blood Proteins; Child; Child Nutritional Physiological Phenomena; Chromatography, Paper; Densitometry; Glutamine; Glycine; Humans; India; Isoleucine; Kwashiorkor; Leucine; Methionine; Nutrition Disorders; Protein-Energy Malnutrition; Serine; Taurine; Valine | 1973 |
Locations of amino acids in brain slices from the rat. Tetrodotoxin-sensitive release of amino acids.
Topics: Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Calcium; Culture Media; Fluoroacetates; Glucose; Glutamates; Glycine; In Vitro Techniques; Male; Malonates; Neuroglia; Neurons; Ouabain; Oxygen Consumption; Potassium; Protoveratrines; Rats; Serine; Tetrodotoxin | 1972 |
D- and L-isomers of serine and alanine equally effective as releasers of gastrin.
Topics: Alanine; Animals; Dogs; Gastrins; Glycine; Serine; Stereoisomerism; Stomach | 1972 |
Carboxyl group modification and amide assignments in automated sequencing of proteins.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Chemical Phenomena; Chemistry; Esters; Glutamates; Glutamine; Glycine; Hydrolysis; Imines; Methanol; Methods; Methylamines; Ribonucleases; Serine; Thiazoles | 1972 |
Cerebral amino acid uptake in vivo in newborn mice.
Topics: Age Factors; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; Blood-Brain Barrier; Brain; Cell Membrane Permeability; Dose-Response Relationship, Drug; Glycine; Histidine; Isoleucine; Methionine; Mice; Serine; Threonine; Tryptophan; Valine | 1972 |
Synthesis of sequence peptide polymers related to collagen.
Topics: Alanine; Amino Acid Sequence; Collagen; Glycine; Hydroxyproline; Methods; Peptides; Polymers; Proline; Serine | 1972 |
Amino acid metabolism in chameleon liver.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Citrulline; Female; Glutamates; Glutamine; Glycine; Histidine; Keto Acids; Liver; Lizards; Lysine; Male; Methionine; Ornithine; Phenylalanine; Pyruvates; Serine; Threonine; Tryptophan | 1972 |
Sequence of limiting amino acids in gelatin for the growing chick.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Weight; Chickens; Female; Gelatin; Glycine; Histidine; Isoleucine; Lysine; Male; Nutritional Requirements; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Valine | 1972 |
[Blood-brain barrier and placental barrier for various amino acids in the mouse (whole body autoradiography studies)].
Topics: Alanine; Amino Acids; Animals; Autoradiography; Blood-Brain Barrier; Cell Membrane Permeability; Female; Glycine; Lysine; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Phenylalanine; Pregnancy; Serine; Tritium; Tyrosine | 1972 |
Research for amino acids in lunar samples.
Topics: Alanine; Amino Acids; Aspartic Acid; Astronomical Phenomena; Astronomy; Chromatography, Gas; Chromatography, Ion Exchange; Extraterrestrial Environment; Geological Phenomena; Geology; Glutamates; Glycine; Hydrolysis; Indicators and Reagents; Oxalates; Serine; Space Flight | 1972 |
An operant method for the study of chemoreception in the green turtle, Chelonia mydas.
Topics: Acetates; Adaptation, Physiological; Alcohols; Aldehydes; Animals; Chemoreceptor Cells; Conditioning, Operant; Environment; Ethylamines; Glycine; Serine; Smell; Turtles | 1972 |
Amino acids and peptides. 34. Synthesis of a structure related to scotophobin.
Topics: Alanine; Amino Acid Sequence; Asparagine; Aspartic Acid; Glutamine; Glycine; Lysine; Memory; Peptides; Serine; Tyrosine | 1972 |
[Amino acid metabolism pathology in the convulsive syndrome in young children].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Child, Preschool; Cystine; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Infant; Infant, Newborn; Leucine; Lysine; Male; Methionine; Proline; Seizures; Serine; Tryptophan; Tyrosine; Valine | 1972 |
The metabolism of oxalate precursors in isolated perfused rat livers.
Topics: Alanine; Animals; Carbon Isotopes; Ethanolamines; Female; Glycine; Glycolates; Glycols; Glyoxylates; Kidney; Liver; Methionine; Oxalates; Oxidation-Reduction; Perfusion; Pyridoxine; Rats; Serine; Thiamine; Thiamine Deficiency; Time Factors; Vitamin B 6 Deficiency | 1972 |
[Correlations of plasma amino acids in the rat during hypercapnia].
Topics: Amino Acids; Analysis of Variance; Animals; Chromatography, Ion Exchange; Glycine; Hypercapnia; Male; Rats; Serine; Threonine | 1972 |
Studies on protamines. XVII. The complete amino acid sequence of clupeine YI.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Cell Nucleus; Chromatography; Fishes; Glycine; Isoleucine; Male; Proline; Protamines; Serine; Spermatozoa; Threonine | 1972 |
[Effect of certain amino acids on the thermostability of animal and plant cells and cellular models].
Topics: Alanine; Amino Acids; Animals; Anura; Chromatography, Paper; Electrophoresis, Paper; Epithelial Cells; Epithelium; Glycerol; Glycine; In Vitro Techniques; Magnoliopsida; Models, Biological; Oviducts; Protein Denaturation; Ranidae; Serine; Thermosensing; Tryptophan | 1972 |
Amino acid inhibition of a 1 -pyrroline-5-carboxylate dehydrogenase preparation from beef kidney mitochondria.
Topics: Alanine; Amino Acid Oxidoreductases; Amino Acids; Animals; Cattle; Glutamates; Glycine; Kidney; Leucine; Mitochondria; Pyrroles; Serine; Valine | 1972 |
Interaction of 4-nitroquinoline 1-oxide and related carcinogens with histone and aliphatic amino acids.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carcinogens; Cattle; Chemical Phenomena; Chemistry; Glutamates; Glycine; Histones; Isoleucine; Leucine; Lysine; Methionine; Proline; Protein Denaturation; Quinolines; Serine; Spectrophotometry; Threonine; Thymus Gland; Valine | 1972 |
Concentration of alpha-amino nitrogen and free amino acid in the uterine and blastocoelic fluid of rabbit.
Topics: Alanine; Amines; Amino Acids; Amniotic Fluid; Animals; Asparagine; Autoanalysis; Blastocyst; Castration; Chromatography, Paper; Embryo Implantation; Estrus; Female; Fertilization; Glutamates; Glutamine; Glycine; Nitrogen; Pregnancy; Pregnancy, Animal; Rabbits; Serine; Time Factors | 1972 |
[Effect of aminazin on metabolism of brain amino acids and gangliosides].
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Chlorpromazine; Galactosamine; Gangliosides; Glutamates; Glycine; Mitochondria; Radiation Injuries, Experimental; Rats; Serine | 1972 |
The stereochemistry of pyridoxal phosphate enzymes. The absolute stereochemistry of cofactor C' 4 protonation in the transamination of holoserine hydroxymethylase by D-alanine.
Topics: Alanine; Aldehydes; Amination; Amino Acids; Animals; Chemical Phenomena; Chemistry; Glycine; Isomerism; Liver; Phosphoric Acids; Protons; Pyridoxal Phosphate; Pyridoxamine; Pyruvates; Serine; Sheep; Tetrahydrofolates; Transaminases; Transferases; Tritium | 1973 |
The solution conformation of the ferrichromes. V. The hydrogen exchange kinetics of ferrichrome analogues; the conformational state of the peptides.
Topics: Aluminum; Amides; Binding Sites; Chemical Phenomena; Chemistry; Deuterium; Gallium; Glycine; Half-Life; Hydrogen; Hydroxamic Acids; Iron Chelating Agents; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Peptides, Cyclic; Protons; Serine; Solubility; Thermodynamics | 1973 |
Amino acid abnormality in Sjögren-Larsson syndrome.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Dental Enamel Hypoplasia; Epilepsy; Ethylamines; Glutamine; Glycine; Histidine; Humans; Ichthyosis; Intellectual Disability; Isoleucine; Leucine; Lysine; Male; Muscle Spasticity; Retinal Degeneration; Serine; Syndrome; Valine | 1973 |
Rat liver aminomalonate decarboxylase. Identity with cytoplasmic serine hydroxymethylase and allothreonine aldolase.
Topics: Alanine; Aldehyde-Lyases; Amino Acids; Animals; Binding Sites; Binding, Competitive; Carbon Isotopes; Carboxy-Lyases; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Glycine; Liver; Male; Malonates; Mitochondria, Liver; Molecular Weight; Protein Denaturation; Rats; Serine; Tetrahydrofolates; Threonine; Transferases; Tritium | 1973 |
Competitive inhibition for amino acid uptake by the indigenous microflora of Upper Klamath Lake.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacteria; Canada; Carbon Dioxide; Carbon Isotopes; Culture Media; Fresh Water; Glutamates; Glycine; Isoleucine; Leucine; Micropore Filters; Plankton; Serine; Valine; Water Microbiology | 1973 |
Folate activity of human lymphocytes determined by measurement of serine synthesis.
Topics: Carbon Dioxide; Carbon Isotopes; Chromatography, Thin Layer; Citric Acid Cycle; Folic Acid; Folic Acid Deficiency; Formates; Glucose; Glycine; Humans; In Vitro Techniques; Lymphocytes; Methionine; Methods; Protein Binding; Pyridoxal Phosphate; RNA; Serine; Tetrahydrofolates | 1973 |
Pyridoxol biosynthesis by Saccharomyces fragilis.
Topics: Acetaldehyde; Acetates; Amino Acids; Aspartic Acid; Carbon Isotopes; Formates; Glucose; Glycine; Kinetics; Methionine; Nicotinic Acids; Picolines; Pyridoxal; Pyridoxine; Pyruvates; Ribose; Saccharomyces; Serine; Tryptophan | 1973 |
A growth factor for animal cells derived from peptone. I. Isolation and characterization of the growth factor.
Topics: Alanine; Aspartic Acid; Chromatography, Gel; Chromatography, Paper; Clone Cells; Culture Media; Culture Techniques; Glutamates; Glycine; Growth Substances; L Cells; Lysine; Molecular Weight; Peptones; Serine; Spectrophotometry; Threonine | 1973 |
Effect of glycl-tRNA concentration on in vitro serine incorporation into the peptidoglycan of S. epidermidis.
Topics: Carbon Isotopes; Chromatography, DEAE-Cellulose; Densitometry; Glycine; In Vitro Techniques; Peptidoglycan; RNA, Bacterial; RNA, Transfer; Serine; Staphylococcus; Tritium | 1973 |
Effect of pentobarbital on amino acid and urea flux in the isolated dog brain.
Topics: Amino Acids; Anesthesia, General; Animals; Asparagine; Aspartic Acid; Brain; Cerebrovascular Circulation; Dipeptides; Dogs; Glutamates; Glutamine; Glycine; Halothane; Isoleucine; Leucine; Methoxyflurane; Nitrogen; Pentobarbital; Proline; Serine; Taurine; Urea; Valine | 1973 |
[Animal experiment studies on uptake of amino acids applied to the nasal mucosa].
Topics: Adsorption; Amino Acids; Aminobutyrates; Animals; Arginine; Biological Transport, Active; Carbon Isotopes; Glutamates; Glycine; Nasal Mucosa; Proline; Rabbits; Serine | 1973 |
Serine transhydroxymethylase. A kinetic study of the synthesis of serine in the absence of tetrahydrofolate.
Topics: Acetaldehyde; Catalysis; Chemical Phenomena; Chemistry; Coenzymes; Feedback; Folic Acid; Formaldehyde; Glycine; Hydrogen; Kinetics; Models, Chemical; Protons; Schiff Bases; Serine; Structure-Activity Relationship; Tetrahydrofolates; Threonine; Transferases; Tritium | 1973 |
Hyperglutamatemia in primary gout.
Topics: Adult; Aged; Alanine; Ammonia; Chromatography; Fasting; Glutamates; Glutamine; Glycine; Gout; Humans; Male; Metabolism, Inborn Errors; Middle Aged; Serine; Threonine; Uric Acid | 1973 |
The reversal of triparanol-induced cataracts in the rat. 3. Amino acid content and uptake of 14 C -AIB in cataractous and clearing lenses.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Cataract; Cystine; Diet; Glutamates; Glycine; Histidine; Isoleucine; Lens, Crystalline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Serine; Threonine; Triparanol; Tyrosine; Valine | 1973 |
Modifications of serum-free amino acid patterns of Babinga adult pygmies after short-term feeding of a balanced diet.
Topics: Adolescent; Adult; Alanine; Amino Acids; Anti-Infective Agents; Black People; Central African Republic; Diet; Dietary Fats; Dietary Proteins; Feeding Behavior; Glutamates; Glycine; Humans; Intestinal Diseases; Male; Nutritional Physiological Phenomena; Phenylalanine; Protein Deficiency; Serine; Time Factors; Tyrosine; Vitamins | 1973 |
The effect of L-3,4-dihydroxyphenylalanine administration on glucose metabolism in brain.
Topics: Administration, Oral; Amino Acids; Animals; Aspartic Acid; Blood Glucose; Brain; Carbon Isotopes; Depression, Chemical; Dihydroxyphenylalanine; Glucose; Glutamine; Glycine; Injections, Intraperitoneal; Kinetics; Lactates; Male; Rats; Serine; Stimulation, Chemical; Taurine; Threonine; Time Factors | 1973 |
Serine-glycine requirement of phytohemagglutinin-stimulated lymphocytes.
Topics: Carbon Isotopes; Cell Division; DNA; Glycine; Humans; Lectins; Leucine; Lymphocytes; Serine; Thymidine | 1973 |
Majors pathways of serine and glycine catabolism in various organs of the rat and cock.
Topics: Animals; Brain; Chickens; Glycine; Intestine, Small; Kidney; L-Serine Dehydratase; Liver; Lung; Male; Methyltransferases; Muscles; Myocardium; Oxidoreductases; Rats; Serine; Spleen; Testis | 1973 |
Amino acid levels in plasma, liver, and skeletal muscle during protein deprivation.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Body Weight; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Liver; Male; Methionine; Muscles; Organ Size; Phenylalanine; Protein Deficiency; Rats; Serine; Threonine; Time Factors; Tyrosine; Valine | 1973 |
The clinical findings in a patient with nonketotic hyperglycinemia.
Topics: Amino Acid Metabolism, Inborn Errors; Diet Therapy; Glycine; Humans; Infant; Intellectual Disability; Liver; Lysosomes; Male; Microscopy, Electron; Serine | 1973 |
Edman degradation on in vitro biosynthesized peptidoglycans from Staphylococcus epidermidis.
Topics: Amino Acid Sequence; Amino Acyl-tRNA Synthetases; Carbon Isotopes; Cell Wall; Cell-Free System; Chromatography, Paper; Cyclization; Glycine; Methods; Peptidoglycan; RNA, Bacterial; RNA, Transfer; Serine; Staphylococcus; Tritium | 1973 |
Fractionation of glycine, alanine, and serine transfer ribonucleic acids from the silk gland.
Topics: Alanine; Animals; Bombyx; Chromatography; Glycine; Larva; RNA, Transfer; Serine | 1973 |
Precursors of glycine in the nervous system: comparison of specific activities in glycine and other amino acids after administration of (U- 14 C) glucose, (3,4- 14 C) glucose, (1- 14 C) glucose, (U- 14 C) serine or (1,5- 14 C) citrate to the rat.
Topics: Amino Acids; Aminobutyrates; Animals; Brain; Carbon Isotopes; Cerebellum; Citrates; Citric Acid Cycle; Glucose; Glycine; Glyoxylates; Male; Medulla Oblongata; Rats; Serine; Spinal Cord | 1973 |
The isolation and properties of a tyrosine-rich protein from wool: component 0.62.
Topics: Animals; Autoanalysis; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Circular Dichroism; Electrophoresis, Starch Gel; Glycine; Hydrogen-Ion Concentration; Isoelectric Focusing; Keratins; Molecular Weight; Phenylalanine; Serine; Sheep; Solubility; Tryptophan; Tyrosine; Ultracentrifugation; Wool | 1973 |
Protein assay in the microgram range: modifications of the Hiraoka-Glick method.
Topics: Animals; Caseins; Cattle; Fluorescent Dyes; Glucose; Glycine; Mathematics; Mercaptoethanol; Methods; Proteins; Serine; Serum Albumin, Bovine; Spectrometry, Fluorescence; Temperature; Time Factors; Urea | 1973 |
Regulation of amino acid transport in chick embryo heart cells. 3. Formal identification of the A mediation as an adaptive transport system.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Carbon Isotopes; Carboxylic Acids; Cell Membrane; Chick Embryo; Glycine; Heart; In Vitro Techniques; Kinetics; Leucine; Lysine; Methylation; Myocardium; Phenylalanine; Serine; Sodium; Time Factors | 1973 |
Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. Crystal structure determination and stereochemistry of the contact region.
Topics: Alanine; Animals; Aspartic Acid; Binding Sites; Cattle; Fourier Analysis; Glycine; Histidine; Kinetics; Lysine; Models, Structural; Pancreas; Protein Conformation; Serine; Trypsin; Trypsin Inhibitors; X-Ray Diffraction | 1973 |
Hybrid formation between collagen and synthetic polypeptides.
Topics: Alanine; Amino Acids; Animals; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Collagen; Glycine; Hybridization, Genetic; Molecular Conformation; Molecular Weight; Optical Rotation; Peptides; Proline; Protein Binding; Protein Conformation; Protein Denaturation; Rabbits; Serine; Skin; Temperature; Tropomyosin | 1973 |
Plasma amino acid patterns in sheep receiving abomasal infusions of methionine and cystine.
Topics: Abomasum; Amino Acids; Animals; Cystathionine; Cystine; Diet; Dose-Response Relationship, Drug; Glycine; Infusions, Parenteral; Isoleucine; Leucine; Male; Methionine; Serine; Sheep; Taurine; Valine | 1973 |
Photosynthetic CO2 incorporation by isolated leaf cell protoplasts.
Topics: Carbon Dioxide; Carbon Radioisotopes; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Chromatography, Thin Layer; Electrophoresis; Glycine; Glycolates; Glyoxylates; Photosynthesis; Plant Cells; Plants; Protoplasts; Serine | 1973 |
Effect of cortisol treatment on free amino acid levels in rats.
Topics: Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Glycine; Hydrocortisone; Liver; Male; Muscle Proteins; Muscles; Proline; Rats; Serine | 1973 |
Carbon 13 nuclear magnetic resonance of pentapeptides of glycine containing central residues of serine, threonine, aspartic and glutamic acids, asparagine, and glutamine.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry; Computers; Fourier Analysis; Glutamates; Glutamine; Glycine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mathematics; Oligopeptides; Protons; Serine; Threonine; Time Factors | 1973 |
Influence of denervation on the free amino acids of the rat diaphragm.
Topics: Alanine; Amino Acids; Animals; Asparagine; Denervation; Diaphragm; Glutamine; Glycine; Liver Regeneration; Male; Rats; Serine; Taurine; Time Factors | 1973 |
Purification and properties of uridine diphosphate N-acetylmuramate: L-alanine ligase.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Carbon Radioisotopes; Cations, Monovalent; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Paper; Electrophoresis, Polyacrylamide Gel; Glycine; Hydrogen-Ion Concentration; Mercaptoethanol; Metals; Muramic Acids; Peptide Synthases; Serine; Staphylococcus; Uracil Nucleotides; Uridine Diphosphate Sugars | 1973 |
Amino acid metabolism in chameleon tissues.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brain; Citrulline; Glutamates; Glutamine; Glycine; Histidine; Ketoglutaric Acids; Kidney; Liver; Lysine; Muscles; Myocardium; Ornithine; Oxaloacetates; Proline; Pyruvates; Reptiles; Serine; Tryptophan | 1973 |
Effect of dietary folic acid deficiency on serine-glycine interconversion and the activity of liver serine hydroxymethyl transferase in the chick.
Topics: Animal Feed; Animals; Body Weight; Chickens; Diet; Folic Acid; Folic Acid Deficiency; Glycine; In Vitro Techniques; Liver; Male; Poultry Diseases; Serine; Tetrahydrofolates; Transferases | 1973 |
New kinetic method for determination of ultramicro quantities of organic substances. Determination of amino acids (glycine, DL-serine, DL-phenylalanine, DL-glutamic acid, and L-arginine).
Topics: Amino Acids; Arginine; Catalysis; Copper; Glutamates; Glycine; Kinetics; Methods; Microchemistry; Oxidation-Reduction; Phenylalanine; Serine | 1973 |
The specific radioactivity of the precursor pool for estimates of the rate of protein synthesis.
Topics: Animals; Carbon Radioisotopes; Diaphragm; Female; Glycine; Hydrolysis; Liver; Muscles; Myocardium; Protein Biosynthesis; Rats; Serine | 1973 |
[Aminoaciduria and aminoacidemia in a case of marble bone disease].
Topics: Amino Acids; Female; Glycine; Humans; Infant; Osteopetrosis; Renal Aminoacidurias; Serine | 1973 |
Cleavage of malyl-Coenzyme A into acetyl-Coenzyme A and glyoxylate by Pseudomonas AM1 and other C1-unit-utilizing bacteria.
Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Bacteria; Bacterial Proteins; Coenzyme A; Coenzyme A Ligases; Glycine; Glyoxylates; Magnesium; Malates; Methane; Oxo-Acid-Lyases; Pseudomonas; Purines; Serine | 1973 |
Free amino acids in E.L.4 mouse ascites tumor cells taken from susceptible (C57BL) and resistant (B10.D2) mice.
Topics: Alanine; Amino Acids; Animals; Arginine; Cell Line; Computers; Depression, Chemical; Glycine; Histidine; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Neoplasms, Experimental; Serine; Species Specificity; Time Factors; Tyrosine | 1973 |
Serine transhydroxymethylase. Studies on the role of tetrahydrofolate.
Topics: Animals; Binding Sites; Carbon Radioisotopes; Catalysis; Deuterium; Formaldehyde; Glycine; Hydrogen-Ion Concentration; Imines; Kinetics; Liver; Models, Chemical; Protons; Rabbits; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet; Tetrahydrofolates; Transferases; Tritium | 1973 |
Quantitative determination of hydrolysis products of phospholipids in the ischaemic rat brain.
Topics: Animals; Brain; Choline; Chromatography, Thin Layer; Ethanolamines; Glycine; Hydrolysis; Inositol; Ischemic Attack, Transient; Phospholipids; Rats; Serine; Time Factors | 1973 |
Functional and modulatory adaptation of tRNA in the silk gland of bombyx mori L. to fibroin biosynthesis.
Topics: Alanine; Amino Acids; Animals; Bombyx; Fibroins; Genetic Code; Glycine; Metamorphosis, Biological; Protein Biosynthesis; RNA, Messenger; RNA, Transfer; Serine; Tyrosine | 1973 |
Postnatal changes in the levels of glycine and the activities of serine hydroxymethyltransferase and glycine:2-oxoglutarate aminotransferase in the rat central nervous system.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Antimetabolites; Brain; Carbon Radioisotopes; Cerebellum; Cerebral Cortex; Chromatography, Ion Exchange; Diencephalon; Glycine; Ketoglutaric Acids; Medulla Oblongata; Mesencephalon; Organ Specificity; Pons; Rats; Serine; Spinal Cord; Tetrahydrofolates; Transaminases; Transferases | 1974 |
Localization of the histidine-rich protein in keratohyalin: a morphologic and macromolecular marker in epidermal differentiation.
Topics: Alanine; Animals; Animals, Newborn; Arginine; Aspartic Acid; Cell Differentiation; Cytoplasmic Granules; Electrophoresis, Polyacrylamide Gel; Glutamates; Glycine; Histidine; Histocytochemistry; Keratins; Macromolecular Substances; Microscopy, Electron; Microscopy, Electron, Scanning; Rats; Serine; Skin; Threonine; Tritium | 1974 |
Renal metabolism of amino acids and ammonia in fed and fasted pregnant sheep.
Topics: Acidosis; Alanine; Amino Acids; Ammonia; Animals; Arginine; Aspartic Acid; Catheterization; Citrulline; Fasting; Female; Glutamates; Glutamine; Glycine; Hypoglycemia; Kidney; Pregnancy; Pregnancy, Animal; Regional Blood Flow; Renal Artery; Serine; Sheep | 1974 |
Selective malabsorption of vitamin B 12: report of a case with metabolic studies.
Topics: Alanine; Amino Acids; Anemia, Macrocytic; Child; Chromatography, Gas; Glycine; Hemoglobins; Histidine; Humans; Isoleucine; Leucine; Malabsorption Syndromes; Male; Malonates; Methionine; Proteinuria; Renal Tubular Transport, Inborn Errors; Reticulocytes; Serine; Taurine; Threonine; Tyrosine; Valine; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Intracellular free amino acid concentration in human muscle tissue.
Topics: Adult; Alanine; Amino Acids; Arginine; Asparagine; Biopsy, Needle; Body Water; Chlorides; Citrulline; Extracellular Space; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Muscles; Ornithine; Phenylalanine; Proline; Serine; Taurine; Tyrosine; Valine | 1974 |
The "intruder" hypothesis and selection against arginine.
Topics: Arginine; Biological Evolution; Genetic Code; Glycine; Immunoglobulins; Lysine; Models, Biological; Mutation; Protein Biosynthesis; RNA, Messenger; Serine | 1974 |
Hyperglutamatemia in primary gout.
Topics: Administration, Oral; Alanine; Erythrocytes; Glutamates; Glutamine; Glycine; Gout; Humans; Male; Puberty; Serine; Threonine; Time Factors; Uric Acid | 1974 |
Interorganal relationships of amino acid metabolism in fed rats.
Topics: Alanine; Amino Acids; Animals; Caseins; Diet; Dietary Proteins; Fasting; Glutamine; Glycine; Kidney; Liver; Liver Circulation; Male; Nitrogen; Rats; Renal Artery; Renal Veins; Serine | 1974 |
Biosynthesis of edeine. Fractionation and characterization of enzymes responsible for biosynthesis of edeine A and B.
Topics: Aminoacylation; Anti-Bacterial Agents; Bacillus; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Glycine; Guanine; Hydrogen-Ion Concentration; Isoelectric Focusing; Kinetics; Molecular Weight; Peptide Biosynthesis; Phosphorus Radioisotopes; Polyamines; Propionates; Serine; Spermidine; Time Factors; Tritium; Tyrosine | 1974 |
The regulation of D-glycerate dehydrogenase from porcine spinal cord.
Topics: Alcohol Oxidoreductases; Animals; Catalysis; Glyceric Acids; Glycine; Pyruvates; Serine; Spinal Cord; Swine | 1974 |
A block in glycine cleavage reaction as a common mechanism in ketotic and nonketotic hyperglycinemia.
Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Carbon Radioisotopes; Child, Preschool; Female; Glycine; Humans; Infant; Infant, Newborn; Liver; Serine; Transferases | 1974 |
A kinetic investigation of the interaction of serine transhydroxymethylase with glycine and serine.
Topics: Binding Sites; Calorimetry; Chemical Phenomena; Chemistry, Physical; Glycine; Hydrogen-Ion Concentration; Kinetics; Oscillometry; Protein Binding; Protein Conformation; Serine; Spectrophotometry; Temperature; Tetrahydrofolates; Thermodynamics; Transferases | 1974 |
[Synthesis routes of the principal amino acids of silk in the silk gland of the silkworm].
Topics: Alanine; Alanine Transaminase; Aldehyde-Lyases; Amino Acids; Aspartate Aminotransferases; Bombyx; Carboxy-Lyases; Electrophoresis, Polyacrylamide Gel; Fibroins; Glycine; Serine; Transferases; Tyrosine | 1974 |
Codon responses of tRNA-Ala, tRNA-Gly and tRNA-Ser from the posterior part of the silkgland of Bombyx mori L.
Topics: Alanine; Animals; Binding Sites; Bombyx; Chromatography, DEAE-Cellulose; Countercurrent Distribution; Genetic Code; Glycine; Micrococcus; Polyribonucleotide Nucleotidyltransferase; Protein Binding; Ribonucleotides; Ribosomes; RNA, Messenger; RNA, Transfer; Serine; Spectrophotometry, Ultraviolet; Tritium | 1974 |
Distribution of serine hydroxymethyltransferase and glycine transaminase in several areas of the central nervous system of the rat.
Topics: Animals; Brain; Carbon Radioisotopes; Centrifugation, Density Gradient; Cerebellum; Glycine; Ketoglutaric Acids; Kinetics; Medulla Oblongata; Mesencephalon; Monoamine Oxidase; Organ Specificity; Pons; Rats; Serine; Serotonin; Spinal Cord; Subcellular Fractions; Succinate Dehydrogenase; Telencephalon; Tetrahydrofolates; Transaminases; Transferases | 1974 |
The clinical and biochemical findings in three cases of hypersarcosinemia and one case of transient hypersarcosinuria associated with folic acid deficiency.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Anemia, Macrocytic; Electrophoresis; Female; Folic Acid Deficiency; Glycine; Humans; Infant; Intellectual Disability; Malabsorption Syndromes; Male; Sarcosine; Serine | 1974 |
Altered amino acid concentrations accompanying suppression of malignancy of mouse melanoma cells by 5-bromodeoxyuridine.
Topics: Alanine; Amino Acids; Animals; Asparagine; Bromodeoxyuridine; Cells, Cultured; Glutamates; Glutamine; Glycine; Lysine; Melanoma; Methionine; Mice; Neoplasm Proteins; Ornithine; Phenylalanine; Pigmentation; Proline; Serine; Threonine; Valine | 1974 |
Plasma and rumen fluid components of steers fed two sources and levels of nitrogen.
Topics: Administration, Oral; Amino Acids; Amino Acids, Essential; Ammonia; Animal Feed; Animals; Arginine; Blood Urea Nitrogen; Body Weight; Cattle; Fatty Acids, Volatile; Glutamates; Glycine; Glycine max; Lysine; Male; Nitrogen; Propionates; Rumen; Serine; Threonine; Urea; Zea mays | 1974 |
Reduction of acute alcoholic intoxication by alpha amino acids: glycine and serine.
Topics: Alcoholic Intoxication; Animals; Behavior, Animal; Chromatography, Gas; Depression, Chemical; Ethanol; Glycine; Humans; Intestinal Absorption; Male; Rats; Serine; Time Factors | 1974 |
A simple method for large-scale preparation of chick embryo tRNA.
Topics: Alanine; Animals; Asparagine; Carbon Radioisotopes; Chick Embryo; Chromatography, DEAE-Cellulose; Chromatography, Gel; Evaluation Studies as Topic; Glycine; Hydrogen-Ion Concentration; Methods; RNA, Transfer; Serine; Threonine; Time Factors; Valine | 1974 |
Reversal by serine and potentiation by glycine of the inhibitory effect of 1,2,4-triazole on growth of Salmonella typhimurium.
Topics: Adenine; Amino Acids; Cysteine; Drug Resistance, Microbial; Drug Synergism; Glycine; Homocysteine; Methionine; Mutation; Salmonella typhimurium; Serine; Triazoles | 1967 |
sRNA specificity for codon recognition as studied by the ribosomal binding technique.
Topics: Alanine; Arginine; Chromatography; Countercurrent Distribution; Escherichia coli; Genetic Code; Glycine; Isoleucine; Leucine; Methionine; Phenylalanine; Polynucleotides; Ribosomes; RNA, Transfer; Serine; Tryptophan; Valine; Yeasts | 1966 |
Glycine uptake in Escherichia coli. I. Glycine uptake by whole cells of Escherichia coli W+ and a D-serine-resistant.
Topics: Biological Transport; Carbon Isotopes; Cell Membrane; Centrifugation, Density Gradient; Chloramphenicol; Detergents; DNA; Escherichia coli; Glycine; Leucine; Lysine; Mutation; Serine | 1968 |
Glycine uptake in Escherichia coli. II. Glycine uptake, exchange, and metabolism by an isolated membrane preparation.
Topics: Alanine; Arsenic; Autoradiography; Azides; Biological Transport; Carbon Isotopes; Cell Membrane; Chromatography, Thin Layer; Cold Temperature; Cyanides; Dinitrophenols; Escherichia coli; Glucose; Glycine; Helium; Hydrazines; Hydrogen-Ion Concentration; Hydroxylamines; Iodoacetates; Magnesium; Mercury; Nucleotides; Phosphatidylethanolamines; Serine; Sulfonic Acids; Threonine | 1968 |
Amino acid transport systems in Escherichia coli K-12.
Topics: Alanine; Amino Acids; Azides; Biological Transport; Calcium; Carbon Isotopes; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Kinetics; Leucine; Methionine; Phenylalanine; Serine; Sodium; Temperature; Tryptophan; Tyrosine; Valine | 1968 |
Chromatographic alterations in transfer RNA's accompanying speciation, differentiation and tumor formation.
Topics: Adenoviridae; Animals; Biological Evolution; Brain; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cattle; Chickens; Chromatography; Cricetinae; Culture Techniques; Embryo, Mammalian; Embryo, Nonmammalian; Escherichia coli; Fibroblasts; Glycine; HeLa Cells; Humans; Kidney; Leucine; Liver; Mice; Muscles; Organ Specificity; Phenylalanine; Rabbits; RNA, Neoplasm; RNA, Transfer; Saccharomyces; Serine; Species Specificity; Tritium; Tyrosine | 1968 |
Effect of amino acids and purine bases on thiamine synthesis by Escherichia coli.
Topics: Adenine; Amino Acids; Aspartic Acid; Culture Media; Cystine; Cytosine; Escherichia coli; Glutamates; Glycine; Guanine; Histidine; Hypoxanthines; Inositol; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Purines; Serine; Thiamine; Thiazoles; Threonine; Thymine; Tyrosine; Uracil; Valine | 1968 |
Suppressor selectrion for amino acid replacements expected on the basis of the genetic code.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bacterial Proteins; Escherichia coli; Genes; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Histidine; Hydro-Lyases; Isoleucine; Leucine; Lysine; Methionine; Mutation; Nucleotides; Phenylalanine; RNA, Messenger; Serine; Suppression, Genetic; Threonine; Tyrosine; Valine | 1967 |
Compartmentation of terpenoid biosynthesis in green plants. A proposed route of acetyl-coenzyme A synthesis in maize chloroplasts.
Topics: Carbon Dioxide; Carbon Isotopes; Chloroplasts; Coenzyme A; Glycine; Glycolates; Glyoxylates; Photosynthesis; Pyruvates; Radioisotope Dilution Technique; Serine; Terpenes | 1969 |
Isolation and partial characterization of Escherichia coli mutants with altered glycyl transfer ribonucleic acid synthetases.
Topics: Carbon Isotopes; Centrifugation, Density Gradient; Culture Media; Escherichia coli; Glycine; L-Serine Dehydratase; Ligases; Mutation; Phenotype; RNA, Bacterial; RNA, Transfer; Serine; Sucrose; Transduction, Genetic; Uridine | 1970 |
Substrate specificity of ribosomal peptidyl transferase. The effect of the nature of the amino acid side chain on the acceptor activity of 2'(3')-O-aminoacyladenosines.
Topics: Acetates; Acyltransferases; Alanine; Amino Acids; Binding Sites; Carbon Isotopes; Escherichia coli; Glutamine; Glycine; Imidazoles; Leucine; Lysine; Methionine; Nucleosides; Peptides; Phenylalanine; Proline; Ribosomes; RNA, Transfer; Serine; Stereoisomerism; Valine | 1970 |
Metabolism of serine and glycine in E. coli K12. I. The role of formate in the metabolism of serine-glycine auxotrophs.
Topics: Adenine; Bacterial Proteins; Carbon Isotopes; Escherichia coli; Formates; Glycine; Methionine; Serine; Temperature; Thymine; Tryptophan; Xanthines | 1970 |
NH2-terminal methionine in nascent peptides from Neurospora crassa.
Topics: Alanine; Carbon Isotopes; Escherichia coli; Glycine; Methionine; Neurospora; Peptide Biosynthesis; Protein Biosynthesis; Puromycin; Ribosomes; Serine | 1971 |
The role of exonuclease and beta protein of phage lambda in genetic recombination. II. Substrate specificity and the mode of action of lambda exonuclease.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Cellulose; Centrifugation, Zonal; Chemical Phenomena; Chemistry; Chromatography; Coliphages; Deoxyribonucleases; DNA, Viral; Electrophoresis; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Methionine; Molecular Weight; Phosphorus Isotopes; Recombination, Genetic; Serine; Tritium; Viral Proteins | 1971 |
Effect of serine hydroxamate on the growth of Escherichia coli.
Topics: Adenine; Alanine; Amino Acids; Carbon Isotopes; Chromatography, Thin Layer; Culture Media; Densitometry; Escherichia coli; Filtration; Glycine; Hydroxamic Acids; Indicators and Reagents; Serine; Spectrophotometry; Stereoisomerism; Tritium | 1971 |
Biochemical bases for the antimetabolite action of L-serine hydroxamate.
Topics: Bacterial Proteins; Carbon Isotopes; Culture Media; Drug Resistance, Microbial; Escherichia coli; Genetics, Microbial; Glycerolphosphate Dehydrogenase; Glycine; Hydroxamic Acids; Leucine; Ligases; Mutagens; Mutation; Nitrosoguanidines; RNA, Bacterial; Serine; Spectrophotometry; Stereoisomerism; Threonine; Tritium; Ultracentrifugation; Uracil | 1971 |
Structure of the porcine LH- and FSH-releasing hormone. I. The proposed amino acid sequence.
Topics: Acetates; Amino Acid Sequence; Amino Acids; Anhydrides; Animals; Arginine; Chemical Phenomena; Chemistry; Chymotrypsin; Endopeptidases; Follicle Stimulating Hormone; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Hypothalamus; Leucine; Luteinizing Hormone; Mass Spectrometry; Methods; Naphthalenes; Peptides; Pituitary Hormone-Releasing Hormones; Proline; Serine; Sulfonic Acids; Swine; Thiocyanates; Tritium; Tryptophan; Tyrosine | 1971 |
[A new method of identification of Shigela cultures].
Topics: Alanine; Ammonia; Bacteriological Techniques; Culture Media; Deamination; Enterobacteriaceae; Glycine; Phenolphthaleins; Serine; Shigella; Stereoisomerism | 1968 |
Regulation of tryptophanase formation in Escherichia coli.
Topics: Alanine; Amino Acids; Culture Media; Cysteine; Enzyme Activation; Escherichia coli; Glycine; Homoserine; Lysine; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phenylalanine; Proteins; Serine; Time Factors | 1971 |
Serine metabolism in the culture form of Trypanosoma cruzi: synthesis of other amino acids.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, Ion Exchange; Cysteine; Glutamates; Glycine; Protein Biosynthesis; Proteins; Serine; Threonine; Trypanosoma cruzi | 1971 |
The isolation and amino acid composition of the enamel proteins of erupted bovine teeth.
Topics: Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Decalcification Technique; Dental Enamel Proteins; Edetic Acid; Glutamates; Glycine; Hydroxyproline; In Vitro Techniques; Serine | 1964 |
Biosynthesis of nucleic acid purines in Mycobacterium tuberculosis H37Rv.
Topics: Chromatography, Ion Exchange; Chromatography, Paper; Formates; Glycine; In Vitro Techniques; Mycobacterium tuberculosis; Nucleic Acids; Purines; Serine | 1966 |
Amino acid content of monkey brain. IV. Effects of chlorpromazine on some amino acids of certain regions of monkey brain.
Topics: Alanine; Amino Acids; Aminobutyrates; Amygdala; Animals; Aspartic Acid; Cerebellum; Chlorpromazine; Chromatography, Paper; Cystine; Female; Frontal Lobe; Glutamine; Glycine; Haplorhini; Hippocampus; Hypothalamus; Male; Mesencephalon; Reserpine; Serine | 1967 |
Amino-acid protection of ultra-violet-irradiated Bacillus subtilis.
Topics: Acid-Base Equilibrium; Alanine; Bacillus subtilis; Culture Media; Glycine; Histidine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays | 1966 |
The NH2-terminal residues of Bacillus subtilis proteins.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus subtilis; Carbon Isotopes; Chromatography, Gel; Escherichia coli; Fluorine; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Nitrobenzenes; Proteins; Ribosomes; Serine; Species Specificity; Threonine; Tritium; Valine | 1968 |
Species differences of serum amino acid beta-napthylamidases.
Topics: Alanine; Amides; Amino Acids; Aminopeptidases; Animals; Arginine; Chickens; Cyprinidae; Dipeptides; Dogs; Female; Glutamine; Glycine; Haplorhini; Humans; Isoleucine; Leucine; Lysine; Methionine; Mice; Naphthalenes; Phenylalanine; Proline; Rats; Serine; Species Specificity; Valine | 1968 |
Bacillus cereus spore germination:absolute requirement for an amine acid.
Topics: Alanine; Amino Acids; Aminobutyrates; Bacillus cereus; Culture Media; Glycine; Hot Temperature; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Nucleosides; Purines; Serine; Spores; Stereoisomerism; Valine | 1968 |
Amino acid pool formation in Pseudomonas aeruginosa.
Topics: Amides; Amino Acids; Arginine; Carbon Isotopes; Chloramphenicol; Cold Temperature; Glutamates; Glycine; Histidine; Kinetics; Membrane Transport Proteins; Nitrogen; Proline; Pseudomonas aeruginosa; Serine; Valine | 1969 |
On the C-terminal amino acid of bacterial alpha-amylase.
Topics: Alanine; Amino Acid Sequence; Amylases; Aspartic Acid; Bacillus subtilis; Carbon; Chemical Phenomena; Chemistry; Electrophoresis; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Paper; Serine; Threonine; Tyrosine; Valine | 1968 |
Serine-containing active center of alkaline proteinase of Aspergillus flavus.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Arthrobacter; Aspergillus; Bacillus subtilis; Binding Sites; Chromatography, Ion Exchange; Chromatography, Paper; Glycine; Isoflurophate; Methionine; Peptide Hydrolases; Phosphorus Isotopes; Serine; Streptomyces; Threonine; Trypsin | 1969 |
Plasma amino acid levels in diabetic ketoacidosis.
Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Arginine; Butyrates; Child; Citrulline; Cystine; Diabetic Ketoacidosis; Female; Glycine; Histidine; Humans; Insulin; Isoleucine; Leucine; Lysine; Male; Methionine; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1970 |
The isolation of gamma-glutamyl peptides from monkey brain.
Topics: Alanine; Animals; Brain Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Glutamates; Glutamine; Glycine; Haplorhini; Isoleucine; Peptides; Serine; Species Specificity; Valine | 1970 |
Purification and properties of dihydroorotase from Escherichia coli B.
Topics: Alkylating Agents; Amidohydrolases; Amino Acids; Arsenic; Buffers; Carbamates; Chromatography, Gel; Cobalt; Edetic Acid; Electrophoresis; Enzyme Activation; Escherichia coli; Glutamates; Glycine; Iodoacetates; Mercury; Molecular Weight; Nitrobenzenes; Organometallic Compounds; Orotic Acid; Phenylacetates; Phosphates; Serine; Silver Nitrate; Succinates; Sulfhydryl Compounds; Sulfonic Acids; Urea; Zinc | 1971 |
Resistance to D-cycloserine in the tubercle bacilli: mutation rate and transport of alanine in parental cells and drug-resistant mutants.
Topics: Alanine; Carbamates; Carbon Isotopes; Cycloserine; Drug Resistance, Microbial; Genetics, Microbial; Glycine; Membrane Transport Proteins; Mutation; Mycobacterium tuberculosis; Serine | 1971 |
[Nitrogen metabolism in parenteral feeding].
Topics: Adult; Aged; Alanine; Amino Acids; Ammonia; Creatinine; Diet Therapy; Duodenal Ulcer; Female; Glycine; Humans; Male; Methionine; Middle Aged; Nitrogen; Parenteral Nutrition; Proline; Serine; Stomach Ulcer; Tryptophan; Urea | 1971 |
Utilization of glyoxylate by acetate-grown Bacillus megaterium KM.
Topics: Acetates; Alcohol Oxidoreductases; Aspartic Acid; Autoradiography; Bacillus megaterium; Carbon Isotopes; Cell-Free System; Chromatography, Paper; Coenzyme A; Culture Media; Glutamates; Glycine; Glycolates; Glyoxylates; Ketoglutaric Acids; Serine; Succinates | 1971 |
Serine biosynthesis in Tetrahymena pyriformis S.
Topics: Acetates; Acyltransferases; Alanine; Aldehyde-Lyases; Animals; Carbon Isotopes; Citric Acid Cycle; Fatty Acids; Formates; Glucose; Glutamates; Glycine; Ketoglutaric Acids; Lactates; Protein Biosynthesis; Pyruvates; Serine; Tetrahymena pyriformis; Threonine | 1971 |
The effect of strychnine and of electrical stimulation on the labelling of -aminobutyric acid and other free amino acids from (U- 14 C)glucose in the spinal cord of the nembutalized rat.
Topics: Alanine; Amino Acids; Aminobutyrates; Anesthesia; Animals; Aspartic Acid; Carbon Isotopes; Electric Stimulation; Glucose; Glutamates; Glutamine; Glycine; Male; Pentobarbital; Rats; Serine; Spinal Cord; Strychnine | 1972 |
The effect of diethyl- -fluoroglutarate on phosphates and glutamate in slices of rabbit cerebral cortex.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Cerebral Cortex; Esters; Fluorine; Glucose; Glutamate Dehydrogenase; Glutamates; Glutamine; Glutarates; Glycine; Oxidative Phosphorylation; Phosphates; Rabbits; Serine; Threonine | 1972 |
The effect of topical application of diethyl- -fluoroglutarate on the metabolism and electrical activity in vivo of cat cerebral cortex.
Topics: Adenosine Triphosphate; Alanine; Aminobutyrates; Ammonia; Animals; Aspartic Acid; Cats; Cerebral Cortex; Electric Stimulation; Electroencephalography; Esters; Fluorine; Glucose; Glucosephosphates; Glutamates; Glutamine; Glutarates; Glycine; Lactates; Malates; Pyruvates; Serine; Synapses; Thalamic Nuclei; Threonine | 1972 |
Function and control of liver alkaline phosphatase.
Topics: Alkaline Phosphatase; Animals; Bile; Cell Membrane; Cell Nucleus; Choline; DNA Replication; Drug Synergism; Fatty Acids; Female; Folic Acid; Glycine; Heparin; Hepatectomy; Hydrocortisone; Liver; Liver Regeneration; Microsomes, Liver; Mitochondria, Liver; Phosphatidylcholines; Rats; Serine; Solubility | 1972 |
Isolation and identification of the messenger RNA for silk fibroin from Bombyx mori.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Bombyx; Centrifugation, Density Gradient; Cytosine; Electrophoresis; Fibroins; Genetic Code; Glycine; Phosphorus Isotopes; Polynucleotides; RNA, Messenger; Serine | 1972 |
The purification and characterization of a novel peptidase from sheep red cells.
Topics: Alanine; Ammonium Sulfate; Animals; Chromatography, DEAE-Cellulose; Dipeptides; Electrophoresis; Endopeptidases; Erythrocytes; Glycine; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Methionine; Molecular Weight; Peptides; Protease Inhibitors; Reticulocytes; Serine; Sheep | 1972 |
Synthesis and structural studies of two collagen analogues: poly (L-prolyl-L-seryl-glycyl) and poly (L-prolyl-L-alanyl-glycyl).
Topics: Circular Dichroism; Collagen; Esters; Glycine; Models, Chemical; Molecular Weight; Peptides; Polymers; Proline; Serine; Solvents | 1972 |
Inactivation of serine transhydroxymethylase and threonine aldolase activities.
Topics: Acetaldehyde; Acetamides; Aldehyde-Lyases; Ammonium Sulfate; Animals; Bromine; Calcium Phosphates; Chemical Precipitation; Chlorine; Enzyme Activation; Gels; Glycine; Iodoacetates; Kinetics; Liver; Pyruvates; Rabbits; Serine; Stereoisomerism; Tetrahydrofolates; Threonine; Transferases | 1972 |
The effect of a single oral dose of lysine or arginine on the excretion of free amino acids by the starved laying hen.
Topics: Administration, Oral; Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Arginine; Chickens; Female; Glycine; Histidine; Isoleucine; Lysine; Ornithine; Serine; Starvation; Time Factors; Tyrosine | 1972 |
Synergy of ethanol and putative neurotransmitters: glycine and serine.
Topics: Animals; Brain Chemistry; Drug Synergism; Ethanol; Glycine; Injections, Intraperitoneal; Mice; Reflex; Serine; Sleep | 1972 |
Amino acid metabolism during starvation in human pregnancy.
Topics: Adolescent; Adult; Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Blood Glucose; Female; Food Deprivation; Gluconeogenesis; Glycine; Humans; Hypoglycemia; Isoleucine; Leucine; Pregnancy; Serine; Starvation; Threonine; Time Factors; Valine | 1972 |
Roles of plasma and erythrocytes in interorgan transport of amino acids in dogs.
Topics: Amino Acids; Animals; Biological Transport; Capillary Permeability; Carbon Isotopes; Cell Membrane Permeability; Dogs; Erythrocytes; Glutamates; Glycine; Hepatic Veins; Intestinal Mucosa; Intestines; Liver; Liver Circulation; Plasma; Portal Vein; Serine | 1972 |
The amino acid composition of spinal fluid protein. Preliminary observations.
Topics: Adolescent; Adult; Amino Acids; Arginine; Cerebrospinal Fluid Proteins; Chromatography; Diffuse Cerebral Sclerosis of Schilder; Female; Glycine; Histidine; Humans; Leucine; Male; Middle Aged; Serine; Subacute Sclerosing Panencephalitis; Valine | 1972 |
Concentration gradients of amino acids between the uterine and blastocoelic fluid in the rabbit.
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Body Fluids; Female; Glutamates; Glycine; Male; Methionine; Methods; Ovum; Pregnancy; Rabbits; Serine; Taurine; Uterus | 1972 |
The aminoaciduria of pregnancy.
Topics: Alanine; Amino Acids; Female; Folic Acid; Glycine; Histidine; Humans; Kidney; Pregnancy; Renal Aminoacidurias; Serine; Statistics as Topic; Threonine | 1972 |
Urinary aminograms in normal infants and children.
Topics: Adolescent; Alanine; Child; Child, Preschool; Glutamates; Glycine; Histidine; Humans; Infant; Infant, Newborn; Renal Aminoacidurias; Serine; Taurine; Tyrosine | 1972 |
Amino acid, creatine and creatinine studies in myotonic dystrophy.
Topics: Adult; Age Factors; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Creatine; Creatinine; Erythrocytes; Female; Glutamine; Glycine; Hemolysis; Humans; Male; Membranes; Middle Aged; Myotonic Dystrophy; Ornithine; Permeability; Serine; Threonine | 1972 |
The effect of dietary lysine level, restriction of food intake and sampling time on the levels of amino acids in the blood plasma of chicks.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Eating; Glycine; Lysine; Proline; Serine; Time Factors | 1972 |
Characterization of three sequential polydipeptides containing glycine.
Topics: Alanine; Amino Acid Sequence; Circular Dichroism; Glutamine; Glycine; Infrared Rays; Microscopy, Electron; Molecular Weight; Peptides; Protein Conformation; Serine; Spectrum Analysis; X-Ray Diffraction | 1972 |
Net metabolism of plasma amino acids by liver and portal-drained viscera of fed sheep.
Topics: Alanine; Amino Acids; Ammonia; Animal Feed; Animals; Arginine; Aspartic Acid; Blood Flow Velocity; Dietary Proteins; Digestive System; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Liver; Liver Circulation; Nitrogen; Ornithine; Phenylalanine; Serine; Sheep; Tyrosine; Valine | 1972 |
Metabolism and interconversions of five plasma amino acids by tissues of the sheep.
Topics: Alanine; Amino Acids; Animal Feed; Animals; Aspartic Acid; Blood Flow Velocity; Carbon Isotopes; Dietary Proteins; Digestive System; Glutamates; Glycine; Hepatic Veins; Liver; Medicago sativa; Portal Vein; Serine; Sheep | 1972 |
Gluconeogenesis from plasma amino acids in fed sheep.
Topics: Alanine; Amino Acids; Animal Feed; Animals; Aorta; Aspartic Acid; Carbon Isotopes; Gluconeogenesis; Glucose; Glutamates; Glycine; Liver; Medicago sativa; Portal Vein; Serine; Sheep | 1972 |
The oxidation of glycine and propionic acid in propionic acidemia with ketotic hyperglycinemia.
Topics: Acidosis; Body Fluids; Carbon Dioxide; Carbon Isotopes; Child, Preschool; Female; Fibroblasts; Glycine; Humans; Infant; Keto Acids; Ligases; Male; Malonates; Oxidation-Reduction; Propionates; Serine | 1972 |
Amino acid patterns in the blood plasma of the young bovine.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Cystine; Female; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1972 |
Oxygen equilibrium characteristics of abnormal hemoglobins. Hirose (alpha-2-beta-2-37Ser), L Ferrara (alpha-2-47-Gly-beta-2), Broussais (alpha-2-90-Asn-beta-2), and Dhofar (alpha-2-beta-2-58Arg).
Topics: Arginine; Asparagine; Aspartic Acid; Electrophoresis, Starch Gel; Genetic Variation; Glycine; Hemoglobins, Abnormal; Heterozygote; Humans; Hydrogen-Ion Concentration; Lysine; Macromolecular Substances; Mathematics; Oxygen; Partial Pressure; Polarography; Proline; Serine; Tryptophan | 1972 |
Synthesis of serine by the dog kidney in vivo.
Topics: Animals; Carbon Isotopes; Dogs; Glutamine; Glycine; Kidney; Renal Artery; Renal Veins; Serine; Threonine | 1972 |
Effects of amino acid compounds injected into cerebrospinal fluid spaces, on colonic temperature, arterial blood pressure and behaviour of the rat.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Apnea; Behavior, Animal; Blood Pressure; Body Temperature; Body Temperature Regulation; Cerebral Ventricles; Cisterna Magna; Colon; Ethyl Ethers; Female; Glycine; Hypotension; Hypothermia; Rats; Reflex; Serine; Stereoisomerism; Taurine | 1972 |
A chemical and crystallographic study of carbamyl-chymotrypsin A.
Topics: Acetates; Amino Acids; Animals; Binding Sites; Carbamates; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Cyanates; Cyanides; Cyanogen Bromide; Cysteine; Glycine; Models, Structural; Nitrophenols; Pancreas; Phenylalanine; Protein Conformation; Serine; Succinates; Water; X-Ray Diffraction | 1972 |
A kinetic investigation of the interaction of serine transhydroxymethylase with glycine.
Topics: Animals; Glycine; Kinetics; Liver; Models, Chemical; Oscillometry; Pyridoxal Phosphate; Rabbits; Serine; Spectrophotometry; Temperature; Tetrahydrofolates; Transferases; Ultraviolet Rays | 1972 |
Endocrine control of free amino acids content in uterine fluid in pregnant rabbits.
Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Body Fluids; Castration; Corpus Luteum; Embryo Implantation; Estradiol; Female; Glycine; Ovary; Pregnancy; Progesterone; Rabbits; Serine; Taurine; Threonine; Uterus | 1972 |
Solution conformation of the ferrichromes. A comparative proton magnetic resonance study of glycine- and serine-containing ferrichromes.
Topics: Basidiomycota; Glycine; Hydrogen; Iron; Magnetic Resonance Spectroscopy; Peptides, Cyclic; Protein Binding; Protein Conformation; Serine; Temperature; X-Ray Diffraction | 1972 |
Serum aminotransferase activities and plasma free amino acid concentration as criteria for pyridoxine nutritional status of chicks.
Topics: Alanine Transaminase; Amino Acids; Aminobutyrates; Ammonia; Animal Nutritional Physiological Phenomena; Animals; Asparagine; Aspartate Aminotransferases; Body Weight; Chickens; Cysteine; Diet; Feeding Behavior; Glutamine; Glycine; Male; Ornithine; Pyridoxal Phosphate; Pyridoxine; Serine; Taurine; Vitamin B 6 Deficiency | 1972 |
[Amino acid sequence of the threonine containing mureins of some species of Streptococcus].
Topics: Alanine; Amino Acid Sequence; Cell Wall; Chromatography, Paper; Chromatography, Thin Layer; Glycine; Peptidoglycan; Phosphates; Serine; Streptococcus; Threonine | 1972 |
Transfer RNA changes in rat granulation tissue possibly related to collagen synthesis.
Topics: Acylation; Amino Acyl-tRNA Synthetases; Animals; Carbon Isotopes; Cellulose; Chromatography, DEAE-Cellulose; Collagen; Glycine; Granulation Tissue; Leucine; Lysine; Male; Proline; Rats; RNA, Transfer; Serine; Time Factors; Tritium | 1972 |
Consequences of glycerol deprivation on the synthesis of membrane components in a glycerol auxotroph of Staphylococcus aureus.
Topics: Acetates; Bacterial Proteins; Carbon Isotopes; Carotenoids; Cell Membrane; Chromatography, Paper; Electron Transport; Fatty Acids; Fatty Acids, Nonesterified; Glucose; Glycerides; Glycerol; Glycine; Glycolipids; Heme; Levulinic Acids; Lipids; Mevalonic Acid; Phosphates; Phospholipids; Phosphorus Isotopes; Serine; Staphylococcus; Vitamin K | 1972 |
Gluconeogenesis and amino acid metabolism. I. Comparison of various precursors for hepatic gluconeogenesis in vivo.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood Glucose; Carbon Isotopes; Cattle; Gluconeogenesis; Glucose Oxidase; Glutamate Dehydrogenase; Glutamates; Glycerol; Glycine; Hexokinase; Histidine; Kinetics; L-Lactate Dehydrogenase; Liver; Male; Rabbits; Rats; Serine; Swine | 1972 |
Adenosine triphosphate synthesis and the natural electron acceptor for synthesis of serine from glycine in leaves.
Topics: Adenosine Triphosphate; Amobarbital; Antimycin A; Carbon Dioxide; Carbon Isotopes; Electron Transport; Ferricyanides; Glycine; Mitochondria, Liver; Plants; Serine | 1972 |
NH 2 -terminal residues of Neurospora crassa proteins.
Topics: Alanine; Amino Acids; Autoanalysis; Cell-Free System; Chromatography, Paper; Culture Media; Dinitrophenols; Glycine; Hydrolysis; Neurospora; Phenylalanine; Proteins; Serine; Spectrophotometry | 1971 |
Effect of excess levels of individual amino acids on growth of rats fed casein diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Caseins; Cystine; Depression, Chemical; Dietary Proteins; DNA; Glutamates; Glycine; Growth; Histidine; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Organ Size; Phenylalanine; Proline; Proteins; Rats; RNA; Serine; Stereoisomerism; Stimulation, Chemical; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Effect of dietary protein level on plasma free amino acids in the chicken.
Topics: Alanine; Amino Acids; Animals; Blood; Body Weight; Caseins; Chickens; Depression, Chemical; Dietary Proteins; Glycine; Isoleucine; Leucine; Lysine; Male; Methionine; Proline; Proteins; Serine; Stimulation, Chemical; Threonine; Tyrosine; Valine | 1971 |
Quantitative changes in plasma amino acids induced by oral contraceptives.
Topics: Adult; Alanine; Amino Acids; Contraceptives, Oral; Female; Glutamine; Glycine; Gonadal Steroid Hormones; Humans; Isoleucine; Leucine; Ornithine; Ovulation; Proline; Serine; Tyrosine; Valine | 1971 |
Quantitative amino acids in amniotic fluid and maternal plasma in early and late pregnancy. Preliminary report.
Topics: Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Arginine; Aspartic Acid; Citrulline; Cystine; Female; Gestational Age; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
Partial identification of a chymotrypsin formed by incubation of bovine chymotrypsinogen A with papain.
Topics: Amino Acid Sequence; Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chymotrypsin; Enzyme Activation; Enzyme Precursors; Glycine; Leucine; Papain; Serine; Spectrophotometry; Time Factors; Ultraviolet Rays | 1971 |
Inhibition of -glutamyl transpeptidase by a mixture of L-serine and borate. Experiments with tissue homogenates and in vivo.
Topics: Acyltransferases; Amides; Amines; Animals; Autoradiography; Borates; Carbon Isotopes; Colorimetry; Electrophoresis; Female; Glutamates; Glycine; Guinea Pigs; Intestines; Kidney; Liver; Lung; Muscles; Myocardium; Naphthalenes; Nitriles; Propionates; Serine; Spleen; Uterus | 1971 |
Daily variations in the concentrations of individual amino acids in rat plasma.
Topics: Alanine; Amino Acids; Animals; Circadian Rhythm; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Phenylalanine; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Aspects of glycine and serine biosynthesis during growth of Pseudomonas AM1 on C compounds.
Topics: Carbon; Culture Media; Formates; Glycerophosphates; Glycine; Glyoxylates; Methanol; Mutation; Pseudomonas; Serine; Transaminases; Transferases | 1971 |
Comparison of amino acid concentrations between plasma and erythrocytes. Studies in normal human subjects and those with metabolic disorders.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Arginine; Aspartic Acid; Biological Transport; Child; Chromatography, Ion Exchange; Cystine; Erythrocytes; Glutamates; Glutathione; Glycine; Histidine; Homocystine; Homocystinuria; Humans; Infant; Maple Syrup Urine Disease; Methionine; Ornithine; Phenylketonurias; Plasma; Renal Tubular Transport, Inborn Errors; Serine; Spectrophotometry; Threonine; Tyrosine | 1971 |
The effect of dietary fluoride on plasma free amino acid concentrations in the rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Diet; Feeding Behavior; Female; Fluorides; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Rats, Inbred Strains; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Studies on the biosynthesis of mitomycin C by Streptomyces verticillatus.
Topics: Acetamides; Acetates; Alanine; Anhydrides; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Formates; Glucose; Glycine; Heptoses; Isoleucine; Leucine; Methionine; Mevalonic Acid; Mitomycins; Models, Biological; Models, Structural; Oxidation-Reduction; Pentosephosphates; Phenylalanine; Serine; Shikimic Acid; Sodium; Spectrophotometry; Streptomyces; Tryptophan; Valine | 1971 |
Conformational and activity changes on subtilisin cleavage of carboxypeptidase A.
Topics: Aspartic Acid; Bacillus; Bacteria; Benzyl Compounds; Binding Sites; Carboxypeptidases; Catalysis; Circular Dichroism; Endopeptidases; Formates; Glycine; Hippurates; Hydrolysis; Isoflurophate; Kinetics; Lactates; Nitrobenzenes; Pancreatic Elastase; Phenylalanine; Pronase; Propionates; Protein Conformation; Serine | 1971 |
Kinetic analysis of insulin action on amino acid uptake by isolated chick embryo heart cells.
Topics: Amino Acids; Animals; Biological Transport; Carbon Dioxide; Carbon Isotopes; Chick Embryo; Fetal Heart; Glycine; Insulin; Inulin; Kinetics; Proline; Serine; Tritium | 1971 |
The amino acid-fermenting clostridia.
Topics: Amino Acids; Arginine; Caseins; Chromatography, Paper; Clostridium; Culture Media; Fermentation; Glucose; Glutamates; Glycine; Histidine; Proline; Serine; Threonine | 1971 |
The effect of vitamin C depletion on the free amino acid content in blood plasma of the guinea pig.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Ascorbic Acid Deficiency; Aspartic Acid; Citrulline; Cysteine; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Time Factors; Tyrosine; Valine | 1971 |
Structure of glycoproteins of human erythrocytes. Alkali-stable oligosaccharides.
Topics: Alkalies; Aspartic Acid; Borohydrides; Chromatography, Gel; Erythrocytes; Fucose; Galactose; Glucosamine; Glucosidases; Glycine; Glycopeptides; Glycoproteins; Humans; Hydrolysis; Mannose; Models, Structural; Molecular Weight; Neuraminic Acids; Oligosaccharides; Serine; Threonine | 1971 |
[Dissociation of S- and P-variants of Bacillus brevis var. G.-B. on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Mutation; Nitrogen; Ornithine; Phenylalanine; Serine; Stimulation, Chemical; Threonine; Time Factors; Tryptophan; Valine | 1971 |
Germination of spores of Clostridium bifermentans by certain amino acids, lactate and pyruvate in the presence of sodium or potassium ions.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Clostridium; Glycine; Histidine; Lactates; Lysine; Ornithine; Phenylalanine; Potassium; Pyruvates; Serine; Sodium; Spores; Spores, Bacterial | 1971 |
[Antineoplastic effect and chemical structure of protamines of various origin].
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Carcinoma, Ehrlich Tumor; Depression, Chemical; Fishes; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Leukemia, Experimental; Lysine; Methionine; Mice; Proline; Protamines; Sarcoma 37; Serine; Threonine | 1971 |
Incorporation of molecular oxygen into glycine and serine during photorespiration in spinach leaves.
Topics: Alkaline Phosphatase; Carboxylic Acids; Chromatography, Gas; Chromatography, Ion Exchange; Chromatography, Paper; Glyceric Acids; Glycerophosphates; Glycine; Glycolates; Kinetics; Light; Oxygen Consumption; Oxygen Isotopes; Phosphoric Acids; Photosynthesis; Plants; Radiation Effects; Serine | 1971 |
Comparative study of various serine proteinases from microorganisms: specificity with oligopeptides.
Topics: Alanine; Aspergillus; Bacillus; Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Disc; Endopeptidases; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Leucine; Peptides; Phenylalanine; Protease Inhibitors; Serine; Species Specificity; Streptomyces; Tyrosine | 1971 |
The role of glycine in the biosynthesis of a terpene.
Topics: Acetates; Autoradiography; Carbon Isotopes; Formates; Fungi; Glycine; Methionine; Sarcosine; Serine; Terpenes | 1971 |
[Formation of CO 2 from C 1 metabolism in ascites tumor cells].
Topics: Amitrole; Animals; Carbohydrate Metabolism; Carbon Dioxide; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Catalase; Formates; Glucose; Glycine; Hydrogen Peroxide; Inosine; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Oxygen Consumption; Serine; Succinates; Transplantation, Homologous | 1971 |
Growth of Pseudomonas reptilivora on glycine.
Topics: Carbon Isotopes; Glycine; L-Serine Dehydratase; Pseudomonas; Serine; Transferases | 1971 |
Sequence and structure of a cysteinyl flavin peptide from monoamine oxidase.
Topics: Amino Acid Sequence; Aminopeptidases; Binding Sites; Chromatography, Paper; Cysteine; Electrophoresis, Paper; Flavin-Adenine Dinucleotide; Fluorometry; Formates; Glycine; Hydrolysis; Indicators and Reagents; Liver; Monoamine Oxidase; Oxidation-Reduction; Peptides; Protein Binding; Serine; Spectrophotometry; Tyrosine | 1971 |
Post mortem changes in the content and specific radioactivity of several amino acids in four areas of the rat brain.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Carbon Isotopes; Cerebellum; Cerebral Cortex; Glutamates; Glutamine; Glycine; Lactates; Male; Medulla Oblongata; Mesencephalon; Pons; Postmortem Changes; Rats; Serine | 1971 |
Carbohydrate and end group analyses of ovine FSH.
Topics: Amino Acid Sequence; Animals; Carbohydrates; Dansyl Compounds; Follicle Stimulating Hormone; Fucose; Glutamates; Glycine; Glycoproteins; Hexosamines; Hexoses; Hydrazines; Neuraminic Acids; Serine; Sheep | 1971 |
The extraction of a protein fraction rich in glycine, serine, tyrosine, and phenylalanine from Merino wool.
Topics: Animals; Chromatography; Dialysis; Electrophoresis, Disc; Ethanol; Glycine; Molecular Weight; Phenylalanine; Proteins; Serine; Sheep; Tyrosine; Wool | 1971 |
Synthesis of some aminoacyl derivatives of 2-acetamido-2-deoxy- -D-glucopyranosylamine and of 2-amino-1-N-(4-L-aspartyl)-2-deoxy- -D-glucopyranosylamine.
Topics: Alanine; Amidohydrolases; Amino Acids; Animals; Aspartic Acid; Circular Dichroism; Fluorine; Glucosamine; Glutamates; Glycine; Glycopeptides; Hexosamines; Hydrogen-Ion Concentration; Hydrolysis; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Optical Rotation; Optical Rotatory Dispersion; Pyrans; Rats; Serine; Valine | 1971 |
The metabolic fate of (vinyl-i-14C)dichlorvos in the rat after oral and inhalation exposure.
Topics: Administration, Oral; Animals; Carbon Dioxide; Carbon Radioisotopes; Chlorine; Chromatography; Dichlorvos; Electrophoresis, Paper; Environmental Exposure; Feces; Female; Glucuronates; Glycine; Hippurates; Injections, Intraperitoneal; Liver; Male; Mass Spectrometry; Radioisotopes; Rats; Serine; Skin; Urea | 1971 |
The isolation from human dentine and ox bone of phosphate-containing peptides.
Topics: Amino Acids; Animals; Arginine; Bone and Bones; Cattle; Chromatography, Thin Layer; Dentin; Electrophoresis; Glutamates; Glycine; Humans; In Vitro Techniques; Peptide Biosynthesis; Phosphates; Serine | 1966 |
Ultrafilterable ninhydrin-positive components of human parotid saliva.
Topics: Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Chromatography, Paper; Glutamates; Glycine; Humans; Indicators and Reagents; Leucine; Lysine; Male; Parotid Gland; Saliva; Serine; Taurine; Valine | 1967 |
Similarities and differences among specific tRNA's in mammalian tissues.
Topics: Alanine; Animals; Brain Chemistry; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cattle; Chick Embryo; Culture Techniques; Fibroblasts; Glycine; HeLa Cells; Humans; Kidney; Leucine; Liver; Lysine; Mice; Muscles; Neoplasms, Experimental; Phenylalanine; Rabbits; RNA, Transfer; Serine; Species Specificity; Threonine; Tritium | 1967 |
Studies on the peptides, free amino acids and certain related compounds isolated from ox bone.
Topics: Amino Acids; Animals; Bone and Bones; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Dicarboxylic Acids; Electrolysis; Glycine; Hydroxyproline; Lysine; Molecular Weight; Ornithine; Peptides; Serine | 1968 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Serine requirement in leukemic and normal blood cells.
Topics: Alanine; Asparagine; Aspartic Acid; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Culture Media; DNA, Neoplasm; Fibroblasts; Glucose; Glutamates; Glycine; Humans; In Vitro Techniques; Leukemia, Myeloid; Neoplasm Proteins; Proline; RNA, Neoplasm; Serine; Thymidine; Tritium; Uridine | 1969 |
Pyridoxine deficiency and brain amino acids.
Topics: Acetates; Alanine; Amino Acids; Aminobutyrates; Animals; Brain; Brain Chemistry; Diet; Glutamates; Glycine; Lactates; Methionine; Mice; Quaternary Ammonium Compounds; Seizures; Serine; Thiosemicarbazones; Tyrosine; Urea; Vitamin B 6 Deficiency | 1969 |
Leaf peroxisomes and their relation to photorespiration and photosynthesis.
Topics: Alcohol Oxidoreductases; Carbon Isotopes; Catalase; Chloroplasts; Cytoplasmic Granules; Darkness; Glycerol; Glycine; Glycolates; Isocitrate Dehydrogenase; Light; Malate Dehydrogenase; Oxygen Consumption; Photosynthesis; Plant Cells; Plants; Serine | 1969 |
Genetics of somatic mammalian cells. X. Complementation analysis of glycine-requiring mutants.
Topics: Animals; Carbon Isotopes; Cell Line; Cricetinae; Culture Techniques; Female; Genes; Genetic Complementation Test; Glycine; Mutation; Ovary; Serine; Tetrahydrofolate Dehydrogenase; Transferases | 1969 |
Isoaccepting transfer RNA's of L-M cells in culture and after tumor induction in C3H mice.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cell Line; Chromatography; Connective Tissue; Culture Media; Culture Techniques; Female; Fibrosarcoma; Glycine; Histidine; Isoleucine; Leucine; Ligases; Lysine; Male; Methionine; Mice; Phenylalanine; Proline; RNA, Transfer; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
Transfer RNA species in normal and leukemic human lymphoblasts.
Topics: Amino Acids; Carbon Isotopes; Cell Line; Chromatography; Glutamine; Glycine; Humans; Leucine; Leukemia, Lymphoid; Ligases; Lymphocytes; Proline; RNA, Transfer; Serine; Threonine; Tritium; Tyrosine | 1970 |
[Distribution of free amino acids in plasma in patients with a chronic lymphatic and acute leukemia].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Citrulline; Cystine; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Leukemia, Lymphoid; Lysine; Methionine; Ornithine; Phenylalanine; Prednisolone; Proline; Serine; Threonine; Triethylenemelamine; Tyrosine; Valine; Vincristine | 1971 |
Serine and aspartic acid metabolism in leukemic leukocytes: correlation to effectiveness of therapy.
Topics: Adult; Aged; Aspartic Acid; Blood Proteins; Carbon Dioxide; Carbon Isotopes; Female; Glycine; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Lipid Metabolism; Male; Middle Aged; Nucleotides; Remission, Spontaneous; Serine | 1971 |
An unusual calcified tumour of the maxilla. A case report and biochemical study.
Topics: Adolescent; Aspartic Acid; Calcinosis; Chromatography, Ion Exchange; Cystine; Female; Glutamates; Glycine; Humans; Hydroxyproline; Isoleucine; Leucine; Maxilla; Maxillary Neoplasms; Serine; Threonine; X-Ray Diffraction | 1971 |
Effects of ionizing radiation on free amino acids in Oedogonium cardiacum.
Topics: Alanine; Chromatography, Thin Layer; Eukaryota; Glutamates; Glycine; Histidine; Leucine; Methionine; Ornithine; Radiation Effects; Serine; Threonine; Valine | 1966 |
Serine biosynthesis and regulation in Haemophilus influenzae.
Topics: Carbon Isotopes; Feedback; Glycerophosphates; Glycine; Haemophilus influenzae; Mutation; Serine | 1969 |
Hyperglycinemia: a defect in glycine cleavage reaction.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Autoanalysis; Carbohydrates; Carbon Dioxide; Carbon Isotopes; Chromatography, Thin Layer; Female; Glycine; Humans; In Vitro Techniques; Infant; Injections, Intravenous; L-Serine Dehydratase; Leucovorin; Liver; Serine; Time Factors; Transferases | 1969 |
Influence of organic acids on the growth of Thiobacillus neapolitanus.
Topics: Acetates; Acids; Alcohol Oxidoreductases; Carbon Isotopes; Cytochromes; Glutamates; Glycine; Glycolates; Glyoxylates; Pyridines; Serine; Succinates; Sulfonic Acids; Thiobacillus | 1970 |
Amino acid replacements associated with reversion and recombination within a coding unit.
Topics: Alanine; Amino Acids; Aspartic Acid; Cysteine; Escherichia coli; Genetic Code; Genetics; Glycine; In Vitro Techniques; Isoleucine; Ligases; Lysine; Mutation; Peptides; Serine; Tryptophan; Valine | 1965 |
Occurrence of hydroxypyruvate-L-glutamate transaminase in Escherichia coli and its separation from hydroxypyruvate-phosphate-L-glutamate transaminase.
Topics: Alanine; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry; Culture Media; Escherichia coli; Glutamates; Glycine; Mutation; Pyruvates; Serine; Spectrophotometry; Transaminases | 1966 |
Imidazolylacetolphosphate:L-glutamate aminotransferase. Composition and substructure.
Topics: Alanine; Ammonia; Arginine; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Electrophoresis; Genes; Glycine; Histidine; Leucine; Methionine; Molecular Biology; Molecular Weight; Peptides; Phenylalanine; Proline; Salmonella typhimurium; Serine; Threonine; Transaminases; Tyrosine; Valine | 1967 |
Modification of leucyl-sRNA after bacteriophage infection.
Topics: Carbon Isotopes; Chromatography; Coliphages; Glycine; Leucine; Ligases; Lysine; Phenylalanine; RNA, Bacterial; RNA, Transfer; RNA, Viral; Serine; Shigella dysenteriae; Tritium; Ultraviolet Rays; Valine; Viral Proteins | 1966 |
Hemoglobins of mice: sequence and possible ambiguity at one position of the alpha chain.
Topics: Amino Acid Sequence; Animals; Chromatography, Ion Exchange; Glycine; Hemoglobins; In Vitro Techniques; Mice; Molecular Biology; Pepsin A; Peptides; Serine; Threonine; Trypsin; Valine | 1967 |
Biochemical studies on Streptomyces aureofaciens. V. The role of cobalamins and methionine in methylation reactions in tetracycline biosynthesis.
Topics: Adenine; Carbon Isotopes; Cobalt; Glycine; Methionine; Methylation; Serine; Streptomyces; Tetracycline; Vitamin B 12 | 1969 |
The postnatal changes in the circulating free amino acid pool in the newborn infant. I. The plasma amino acid ratio in normal full-term and preterm infants.
Topics: Amino Acids; Blood Chemical Analysis; Chromatography, Paper; Gestational Age; Glutamine; Glycine; Humans; Infant, Newborn; Infant, Premature; Isoleucine; Leucine; Methionine; Serine; Taurine; Valine | 1969 |
Effect of urea on the optical rotatory dispersion of diketopiperazines of L-serine, L-alanine, L-lysine, L-valine, and L-valylglycine.
Topics: Alanine; Amino Acids; Chemical Phenomena; Chemistry; Dipeptides; Glycine; Lysine; Methods; Optical Rotatory Dispersion; Peptides; Piperazines; Rotation; Serine; Spectrophotometry; Stereoisomerism; Ultraviolet Rays; Urea; Valine; Water | 1969 |
[Transport of amino acids across lymphocyte membrane in human peripheral blood].
Topics: Amino Acids; Aspartic Acid; Biological Transport, Active; Cell Membrane; Glycine; Humans; Kinetics; Leucine; Lymphocytes; Lysine; Methionine; Proline; Radioisotopes; Serine; Temperature | 1969 |
[Model reactions for enzymatic catalysis. II. Further studies on non-enzymatic transamination with 2-formylimidazoles].
Topics: Amino Acids; Ammonia; Aspartic Acid; Catalysis; Cobalt; Copper; Cystine; Formates; Glycine; Hydro-Lyases; Imidazoles; Iron; Models, Chemical; Nickel; Pyruvates; Serine; Threonine; Zinc | 1969 |
Nonketotic hyperglycinemia.
Topics: Agranulocytosis; Amino Acid Metabolism, Inborn Errors; Benzoates; Body Weight; Carbon Isotopes; Diet Therapy; Dietary Proteins; Glycine; Humans; Infant, Newborn; Infant, Newborn, Diseases; Intellectual Disability; Male; Myoclonus; Serine | 1969 |
Isolation and characterization of polypeptides of human serum lipoproteins.
Topics: Amino Acids; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Electrophoresis, Disc; Female; Glutamates; Glycine; Humans; Lipoproteins; Male; Methods; Peptides; Serine | 1969 |
Goat immunolobulin G. Peptide chains and terminal residues.
Topics: Amino Acid Sequence; Amino Acids; Animals; Dipeptides; Glycine; Goats; Immunoglobulin G; Molecular Weight; Peptides; Pyrrolidinones; Serine | 1969 |
Structural comparison of the hemoglobins of the genus Equus with those of ruminants.
Topics: Alleles; Amino Acid Sequence; Amino Acids; Animals; Biological Evolution; Blood Protein Electrophoresis; Chemical Phenomena; Chemistry; Female; Glycine; Hemoglobins; Horses; Male; Methods; Models, Biological; Molecular Biology; Peptides; Perissodactyla; Phenylalanine; Polymorphism, Genetic; Serine; Sheep; Species Specificity; Tyrosine | 1969 |
One-carbon metabolism in the developing ovary of the housefly Musca domestica.
Topics: Animals; Carbon; Carbon Isotopes; Female; Formates; Glycine; Houseflies; Ovary; RNA; Serine | 1969 |
Changes in free amino acids of tomato fruit under pathogenesis.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Fruit; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Plant Diseases; Serine; Threonine; Tyrosine; Valine | 1969 |
Liver-L-alanine-glyoxylate and L-serine-pyruvate aminotransferase activities: an apparent association with gluconeogenesis.
Topics: Alanine; Animals; Anura; Dogs; Gluconeogenesis; Glycine; Glyoxylates; Liver; Pyruvates; Rabbits; Rats; Serine; Swine; Transaminases | 1969 |
Effect of protein and riboflavin on plasma amino acids and hepatic riboflavin-coenzymes in the rat.
Topics: Amino Acids; Analysis of Variance; Animals; Body Weight; Caseins; Depression, Chemical; Diet; Dietary Proteins; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Glutens; Glycine; Liver; Lysine; Male; Metabolism; Rats; Riboflavin; Serine; Stimulation, Chemical; Threonine; Triticum | 1969 |
The nature of amino-acid chloranil complexes.
Topics: Amino Acids; Chemical Phenomena; Chemistry, Physical; Glutamates; Glycine; Hydrogen-Ion Concentration; Infrared Rays; Quinones; Serine; Spectrophotometry; Tryptophan; Tyrosine; Valine | 1969 |
[Comparative study of the alanine-glyoxylate transaminase and malate synthetase in Neurospora crassa].
Topics: Acetates; Alanine; Citrates; Enzyme Induction; Glycine; Glyoxylates; Lyases; Malates; Mutation; Neurospora; Pyruvates; Serine; Transaminases | 1969 |
[Chemical and physico-chemical properties of placental protein with antineoplastic effect].
Topics: Alanine; Amino Acids; Ammonia; Antineoplastic Agents; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Electrophoresis; Female; Glutamates; Glycine; Histidine; Humans; Leucine; Lysine; Phenylalanine; Placenta; Proline; Proteins; Serine; Threonine; Tyrosine; Valine | 1969 |
[The effect of nutrition on the amino acid sequence of the serine containing murein of Staphylococcus epidermis strain 24].
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Cell Wall; Chromatography, Paper; Culture Media; Glutamates; Glycine; Muramidase; Serine; Staphylococcus | 1969 |
The postnatal changes in the circulating free amino acid pool in the newborn infant. II. The plasma amino acid ratio in intrauterine malnutrition (small for dates' full-term, preterm and twin infants).
Topics: Amino Acids; Birth Weight; Chromatography, Paper; Female; Fetal Diseases; Gestational Age; Glutamine; Glycine; Humans; Infant, Newborn; Infant, Premature; Isoleucine; Leucine; Methionine; Nutrition Disorders; Pregnancy; Serine; Taurine; Twins; Valine | 1969 |
Study on the amino acid composition in the cornea of hypophysectomized rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cornea; Cystine; Electrophoresis; Glutamates; Glycine; Growth Hormone; Histidine; Hypophysectomy; Leucine; Lysine; Methionine; Phenylalanine; Pituitary Gland; Rats; Serine; Threonine; Tyrosine | 1969 |
[The intensity of glycine conversion to serine, aspartate and glutamate in the brain under normal conditions and in hypoxia].
Topics: Animals; Aspartic Acid; Brain; Brain Chemistry; Carbon Isotopes; Glutamates; Glycine; Hypoxia, Brain; Rats; Serine | 1969 |
Homocysteine-induced convulsions in the rat: protection by homoserine, serine, betaine, glycine and glucose.
Topics: Animals; Betaine; Glucose; Glycine; Homocysteine; Male; Rats; Seizures; Serine; Time Factors | 1969 |
[Genetic polymorphism in the constant portion of human immunoglobulin lambda-type L chains].
Topics: Amino Acid Sequence; Bence Jones Protein; Chromatography, Ion Exchange; Glycine; Humans; Immunoglobulin G; Molecular Biology; Peptides; Polymorphism, Genetic; Serine | 1970 |
The mechanism of action of serine transhydroxymethylase.
Topics: Folic Acid; Formaldehyde; Glycine; Models, Chemical; Pyridoxal Phosphate; Serine; Transferases; Tritium | 1970 |
The importance of dispensable amino acids for maximal growth in the rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Body Weight; Citrates; Diet; Glutamates; Glycine; Growth; Male; Nutritional Requirements; Proline; Rats; Serine | 1970 |
Biosynthesis of amino acids in Clostridium pasteurianum.
Topics: Alcohol Oxidoreductases; Amino Acids; Aspartic Acid; Carbon Isotopes; Clostridium; Glucose; Glutamates; Glycine; Phosphoglycerate Kinase; Pyruvates; Serine; Threonine; Transaminases | 1970 |
An amino-acid receptor in the guinea-pig ileum.
Topics: Alanine; Animals; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Glycine; Guinea Pigs; Ileum; Receptors, Drug; Serine | 1970 |
Studies on protein-like products from radiofrequency plasmas of Co, N2 and H2.
Topics: Alanine; Carbon Monoxide; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Glutamates; Glycine; Hydrogen; Nitrogen; Proteins; Pyridines; Serine; Tyrosine; Ultraviolet Rays | 1970 |
Nonketotic hyperglycinemia: an in vitro study of the glycine-serine conversion in liver of three patients and the effect of dietary methionine.
Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Biopsy; Carbon Isotopes; Culture Techniques; Diet Therapy; Female; Glycine; Humans; Infant; Infant, Newborn; Intellectual Disability; Liver; Methionine; Serine | 1970 |
Stereospecificity of enzymatic formation and oxidation of glycine.
Topics: Amino Acid Oxidoreductases; Aspartic Acid; Glycine; Glyoxylates; Monoamine Oxidase; Oxidation-Reduction; Serine; Stereoisomerism; Transferases; Tritium | 1970 |
[Glycinosis with acidocetosis of late revelation and favorable evolution].
Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Glutamates; Glycine; Glyoxylates; Humans; Infant; Intelligence; Leucine; Male; Osteoporosis; Oxalates; Psychomotor Disorders; Serine | 1970 |
Levels of amino acids and proteins in Pacinian corpuscles of the cat.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cats; Chromatography, Paper; Denervation; Glutamates; Glutamine; Glycine; Mesentery; Nerve Endings; Nerve Tissue Proteins; Pargyline; Reserpine; Serine; Threonine | 1970 |
Comparative sensitivity of specific amino acid ratios versus "essential to nonessential" amino acid ratio.
Topics: Adult; Amino Acids; Child; Cystine; Diet; Female; Glycine; Humans; Isoleucine; Kwashiorkor; Leucine; Nutrition Disorders; Pregnancy; Serine; Socioeconomic Factors; Tyrosine; Valine | 1970 |
Derivation of partial sequence of human beta chain messenger RNA from mutation data.
Topics: Alanine; Arginine; Genetic Code; Glycine; Hemoglobins; Humans; Leucine; Mutation; Nucleotides; Proline; RNA, Messenger; Serine; Threonine; Valine | 1970 |
Isolation and partial characterization of highly purified protocollagen proline hydroxylase.
Topics: Alcohols; Amino Acids; Animals; Aspartic Acid; Benzoates; Chick Embryo; Chromatography, Gel; Collagen; Electrophoresis, Disc; Ethylmaleimide; Glutamates; Glycine; Isoflurophate; Lysine; Mercury; Methods; Mixed Function Oxygenases; Molecular Weight; Proline; Serine; Sulfur; Ultracentrifugation | 1970 |
Proton magnetic resonance study of the interaction of amino acids and dipeptides with sRNA.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Dipeptides; Glycine; Leucine; Magnetic Resonance Spectroscopy; RNA, Transfer; Serine | 1970 |
[Aspects of phospholipid metabolism in Tribolium confusum].
Topics: Amino Alcohols; Animals; Carbon Isotopes; Choline; Coleoptera; Glycine; Glyoxylates; Phospholipids; Serine; Sterols; Triglycerides | 1970 |
Crystalline threonine aldolase from Candida humicola.
Topics: Acetaldehyde; Aldehyde-Lyases; Candida; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Electrophoresis, Disc; Glycine; Hydrogen-Ion Concentration; Methods; Molecular Weight; Pyridoxal Phosphate; Serine; Spectrum Analysis; Threonine; Ultracentrifugation; Ultraviolet Rays | 1970 |
Prediction and explanation of chemical mutation sites.
Topics: Arginine; Asparagine; Genetic Code; Genetics, Microbial; Glycine; Leucine; Models, Chemical; Mutagens; Mutation; Nucleotides; Phenylalanine; Proline; RNA, Viral; Serine; Tobacco Mosaic Virus | 1970 |
[Study of chemical composition and antineoplastic effect of protamines isolated from the milt of sturgeon fishes].
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Chromatography, Thin Layer; Depression, Chemical; Electrophoresis; Fishes; Glutamates; Glycine; Histidine; Leucine; Lysine; Male; Methionine; Mice; Molecular Weight; Neoplasms, Experimental; Nucleic Acids; Proline; Protamines; Sarcoma 37; Serine; Spectrum Analysis; Sulfates; Threonine; Ultraviolet Rays | 1970 |
Circadian ythm of human urinary amino acid excretion in fed and fasted states.
Topics: 17-Hydroxycorticosteroids; Adult; Alanine; Amino Acids; Asparagine; Circadian Rhythm; Cystinuria; Fasting; Feeding Behavior; Glutamates; Glutamine; Glycine; Humans; Male; Middle Aged; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1970 |
[Biosynthesis of gramicidin C on synthetic media with amino acids as the only N source].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Tyrothricin; Valine | 1970 |
Invertebrate structure proteins. Characterization of the operculum of the gastropod mollu Buccinum undatum.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbohydrates; Chromatography, Gas; Fucose; Galactose; Glucose; Glycine; Mannose; Mollusca; Proteins; Serine; Solubility; Solvents; X-Ray Diffraction; Xylose | 1970 |
Synthesis of serine by rat kidney in vivo and in vitro.
Topics: Animals; Carbon Isotopes; Chromatography; Glucose; Glutamates; Glutamine; Glycerol; Glycine; In Vitro Techniques; Kidney; Male; Rats; Sarcosine; Serine; Time Factors; Transferases | 1970 |
The pathway of glycollate utilization in Chlorella pyrenoidosa.
Topics: Carbon Isotopes; Chlorophyta; Citric Acid Cycle; Glycine; Glycolates; Malates; Photosynthesis; Serine; Transferases | 1970 |
[Biosynthesis of the C9-10 unit of indole alkaloids].
Topics: Alkaloids; Carbon Isotopes; Glycine; Glyoxylates; Indoles; Leucine; Plants, Medicinal; Serine; Strychnine; Tryptophan | 1970 |
Changes in the concentration of specific amino acids in the serum of experimentally malnourished pigs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Dietary Proteins; Female; Gluconeogenesis; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Protein Deficiency; Serine; Swine; Threonine; Tyrosine; Valine | 1970 |
Methionine toxicity and ornithine delta-aminotransferase in Chang's liver cells.
Topics: Arginine; Carbon Isotopes; Cell Division; Cell Line; Glycine; Histidine; Homocysteine; Humans; Kidney; Leucine; Liver; Methionine; Ornithine; Proteins; Serine; Stimulation, Chemical; Transaminases; Tryptophan; Tyrosine | 1970 |
Histidinemia.
Topics: Acetates; Acrylates; Adolescent; Alanine; Glycine; Histidine; Humans; Imidazoles; Lactates; Lyases; Male; Metabolism, Inborn Errors; Purpura, Thrombocytopenic; Pyruvates; Serine; Threonine | 1970 |
A comparison of properties of the alpha-lytic protease of Sorangium sp. and porcine elastase.
Topics: Alanine; Amino Acids; Animals; Deuterium; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Ketones; Kinetics; Leucine; Myxomycetes; Optical Rotatory Dispersion; Pancreatic Elastase; Peptide Hydrolases; Serine; Swine | 1970 |
Gibbon fibrinopeptides: identification of a glycine-serine allelism at position B-3.
Topics: Alleles; Amino Acid Sequence; Amino Acids; Animals; Chymotrypsin; Fibrin; Glycine; Heterozygote; Hominidae; Homozygote; Molecular Biology; Peptides; Plasmapheresis; Serine | 1970 |
Determination of pico-mole quantities of gamma-amino-butyric acid (GABA) and serotonin.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoradiography; Brain Chemistry; Carbon Isotopes; Cerebellum; Chromatography; Cysteine; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methods; Microchemistry; Phenylalanine; Proline; Radionuclide Imaging; Rats; Serine; Serotonin; Threonine; Tyrosine; Valine | 1970 |
Amino acid permeability of pea chloroplasts as measured by osmotically determined reflection coefficients.
Topics: Alanine; Amides; Amino Acids; Cell Membrane Permeability; Chloroplasts; Glycine; Imines; Isoleucine; Leucine; Methionine; Osmolar Concentration; Osmotic Pressure; Phenylalanine; Plants; Proline; Serine; Sucrose; Threonine; Valine | 1970 |
Effect of glycine and serine on methionine metabolism in rats fed diets high in methionine.
Topics: Adaptation, Physiological; Animal Feed; Animals; Body Weight; Carbon Isotopes; Glycine; Intestinal Absorption; Intestinal Mucosa; Methionine; Oxidation-Reduction; Rats; Serine | 1970 |
The metabolism in vivo of glycine and serine in eight areas of the rat central nervous system.
Topics: Amino Acids; Animals; Brain Stem; Carbon Isotopes; Central Nervous System; Cerebellum; Diencephalon; Glucose; Glycine; Male; Medulla Oblongata; Mesencephalon; Nervous System; Pons; Rats; Serine; Spinal Cord; Telencephalon | 1970 |
Microbial growth on oxalate by a route not involving glyoxylate carboligase.
Topics: Bacteria; Carboxy-Lyases; Coenzyme A; Formates; Glycine; Oxalates; Oxidoreductases; Pseudomonas; Serine; Transaminases; Vibrio | 1970 |
Studies on the protein portion of thyroglobulin. Amino acid compositions and terminal amino acids of several thyroglobulins.
Topics: Alanine; Amides; Amino Acids; Animals; Aspartic Acid; Carboxypeptidases; Cattle; Cystine; Fluorine; Glutamates; Glycine; Humans; Hydrazines; Iodine; Leucine; Monosaccharides; Nitrobenzenes; Serine; Sheep; Swine; Thyroglobulin; Thyroid Gland | 1970 |
[Intensity of serine, aspartate and glutamate metabolism in brain and liver at different periods after injection of glycine-2C14].
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Carbon Isotopes; Glutamates; Glycine; Liver; Rats; Serine | 1970 |
Glycine formation via threonine and serine aldolase. Its interrelation with the pyruvate formate lyase pathway of one-carbon unit synthesis in Clostridium kluyveri.
Topics: Carbon; Carbon Isotopes; Chemical Phenomena; Chemistry; Clostridium; Formates; Fructose-Bisphosphate Aldolase; Glycine; Hydrogen-Ion Concentration; Lyases; Pyruvates; Serine; Stereoisomerism; Threonine | 1970 |
Different behaviour of 3H-glycine and 14C-glycine in studies of mammalian tissue metabolism.
Topics: Animals; Brain; Carbon Isotopes; Glycine; Kidney; Liver; Liver Extracts; Muscles; Myocardium; Rats; Serine; Tissue Extracts; Tritium | 1970 |
[Correlation between Parkinsonism symptoms and a disorder in the amino acid metabolism in CNS].
Topics: Amino Acids; Animals; Brain Injuries; Central Nervous System Diseases; Cerebrospinal Fluid; Cysteine; Cystine; Diagnosis, Differential; Glycine; Humans; Parkinson Disease; Parkinson Disease, Postencephalitic; Phenothiazines; Rats; Serine; Threonine; Tremor | 1970 |
X-ray diffraction studies of enzymes.
Topics: Albumins; Binding Sites; Carboxypeptidases; Catalysis; Chemical Phenomena; Chemistry; Chymotrypsin; Enzymes; Glycine; Methods; Models, Structural; Muramidase; Pancreas; Papain; Peptide Hydrolases; Protein Binding; Ribonucleases; Serine; Thermodynamics; Tyrosine; X-Ray Diffraction | 1970 |
Metabolism of alpha-beta-diaminopropionate in a Pseudomonas sp.
Topics: Amino Acids; Ammonia; Glycine; Lyases; Propionates; Pseudomonas; Pyruvates; Serine | 1970 |
[Constitution of the hemoglobin of the toad Bufo bufo spinosus].
Topics: Alanine; Amino Acids; Animals; Anura; Arginine; Chromatography, Gel; Formates; Glycine; Hemoglobins; Histidine; Hydrazines; Lysine; Methionine; Peptide Hydrolases; Serine; Spectrum Analysis | 1970 |
Extracellular glycoproteins of Candida bogoriensis.
Topics: Amino Acids; Candida; Chromatography, Gel; Fucose; Galactose; Glucose; Glutamates; Glycine; Glycoproteins; Mannose; Molecular Weight; Rhamnose; Serine; Sodium Hydroxide; Ultracentrifugation; Uronic Acids | 1970 |
The alpha beta-elimination of L-serylglycine O-sulphate and related dipeptides.
Topics: Catalysis; Copper; Dipeptides; Glycine; Pyridoxal Phosphate; Serine; Sulfates | 1970 |
[Effect of amino acids on the growth of Streptococcus lactis and biosynthesis of nisin].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Depression, Chemical; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Stimulation, Chemical; Streptococcus; Threonine; Tryptophan; Valine | 1970 |
Properties and substrate specificities of the phenylalanyl-transfer-ribonucleic acid synthetases of Aesculus species.
Topics: Alanine; Calcium Chloride; Caproates; Chromatography, DEAE-Cellulose; Glycine; Kinetics; Ligases; Magnesium; Phenylalanine; Plants; Potassium; RNA, Transfer; Seeds; Serine; Species Specificity | 1970 |
[Amino acid composition of calf skin proteins and radiation effects].
Topics: Amino Acids; Animals; Arginine; Asparagine; Cattle; Chromatography, Paper; Cystine; Glutamine; Glycine; Histidine; Proteins; Radiation Effects; Serine; Skin | 1970 |
Amino-terminal-blocked tripeptide analogues of the active site of -chymotrypsin.
Topics: Acrylates; Amino Acid Sequence; Amino Acids; Aspartic Acid; Barium; Benzyl Compounds; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chymotrypsin; Formates; Furans; Glycine; Hydrogen; Hydrolysis; Hydroxides; Imidazoles; Methods; Oxidation-Reduction; Peptides; Serine | 1970 |
[Effect of vitamin E and selenium on glycine-2-C 14 and formate-C 14 incorporation in rat liver glutathione].
Topics: Animals; Carbon Isotopes; Cysteine; Formates; Glutathione; Glycine; Liver; Methionine; Rats; Selenium; Serine; Vitamin E | 1970 |
An investigation of the conformational changes in histones F1 and F2a1 by proton magnetic resonance spectroscopy.
Topics: Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Glycine; Histones; Magnetic Resonance Spectroscopy; Muramidase; Optical Rotatory Dispersion; Osmolar Concentration; Papain; Proline; Ribonucleases; Serine; Sodium Chloride; Threonine | 1970 |
The amino acid ratio and hydroxyproline creatinine index in marginal protein-calorie malnutrition.
Topics: Amino Acids; Animals; Body Weight; Child, Preschool; Chromatography, Paper; Creatinine; Diet; Female; Glutamine; Glycine; Humans; Hydroxyproline; Infant; Infant Nutrition Disorders; Isoleucine; Leucine; Male; Methionine; Milk; Protein Deficiency; Serine; Taurine; Uganda; Valine | 1970 |
Effect of vitamin B6 depletion in adult man on the plasma concentration and the urinary excretion of free amino acids.
Topics: Adult; Alanine; Amino Acids; Fasting; Glycine; Humans; Isoleucine; Leucine; Male; Pyridoxine; Serine; Threonine; Valine; Vitamin B 6 Deficiency | 1971 |
One-carbon metabolism in microorganisms. I. Oxidative demethylation in a sarcosine-utilizing bacterium.
Topics: Bacteria; Carbon Dioxide; Carbon Isotopes; Cytochromes; Electron Transport; Flavins; Fluorescence; Formaldehyde; Glycine; Hydrolases; Imines; Iron; Oxidation-Reduction; Oxidoreductases; Phenazines; Pigments, Biological; Quaternary Ammonium Compounds; Quinones; Sarcosine; Serine; Soil Microbiology; Spectrophotometry; Sulfates; Ultracentrifugation; Vibration | 1971 |
Uranyl nitrate inhibition of transport systems in Saccharomyces cerevisiae.
Topics: Biotin; Carbon Isotopes; Depression, Chemical; Filtration; Glycine; Maltose; Nitrates; Oxygen Consumption; Saccharomyces; Serine; Uranium | 1971 |
The postnatal changes in the circulating free amino acid pool in the newborn infant. 3. The plasma amino acid ratio in infants born after pregnancies complicated by toxaemia, placental infarction, impaired umbilical circulation and chronic maternal diseas
Topics: Amino Acids; Chronic Disease; Female; Glutamine; Glycine; Heart Defects, Congenital; Heart Failure; Humans; Infant, Newborn; Infarction; Isoleucine; Leucine; Maternal-Fetal Exchange; Methionine; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Pyelonephritis; Serine; Taurine; Torsion Abnormality; Umbilical Cord; Valine | 1971 |
A fragment of the third component of human complement with anaphylatoxin activity.
Topics: Amino Acids; Animals; Arginine; Autoanalysis; Carboxypeptidases; Chromatography, Gel; Complement System Proteins; Electrophoresis; Electrophoresis, Disc; Glutamates; Glycine; Guinea Pigs; Humans; Hydrogen-Ion Concentration; Hydroxylamines; Leucine; Molecular Weight; Muscle Contraction; Muscle, Smooth; Peptide Hydrolases; Peptides; Serine; Stimulation, Chemical; Sulfhydryl Compounds; Toxins, Biological; Trypsin; Ultracentrifugation | 1971 |
Quantitative ultramicroanalysis of amino acids in the form of their DNS-derivatives. II. On the use of the dansylation reaction for quantitative estimation of amino acids.
Topics: Amino Acids; Chromatography, Thin Layer; Fluorescence; Glycine; Leucine; Mathematics; Methods; Microchemistry; Naphthalenes; Proline; Serine; Sulfonic Acids; Time Factors | 1971 |
[The flagellar apparatus of Rhodopseudomonas palustris. VI. Characterization of flagellin].
Topics: Alanine; Aspartic Acid; Bacterial Proteins; Electrophoresis; Flagella; Gels; Glycine; Leucine; Molecular Weight; Pseudomonas; Serine; Threonine; Ultracentrifugation | 1971 |
Amino acid metabolism in the isolated perfused rat liver.
Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Chromatography; Glutamates; Glycine; In Vitro Techniques; Liver; Lysine; Male; Methionine; Nitrogen Isotopes; Perfusion; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Urea | 1971 |
The entry of amino acids into the skeletal muscle of the rat in vivo.
Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Biological Transport; Glycine; Leucine; Muscle Proteins; Muscles; Rats; Serine; Taurine; Tryptophan | 1971 |
[Use of methyl group labelled methionine as a source of Cl4 and H3 for the preliminary production of labelled olivomycin by biosynthesis].
Topics: Acetates; Actinomyces; Alanine; Amino Acids; Antibiotics, Antineoplastic; Aspartic Acid; Carbon Isotopes; Chloramphenicol; Depression, Chemical; Fermentation; Formates; Glucose; Glutamates; Glycine; Methionine; Olivomycins; Phenylalanine; Serine; Stimulation, Chemical; Time Factors; Tritium | 1971 |
[Dissociation of R- and P plus-variants of Bacillus brevis var. G.-B. during growth on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Valine | 1971 |
The entry of amino acids into the myocardium of the growing rat in vivo.
Topics: Amino Acids; Animals; Aspartic Acid; Diffusion; Glycine; Heart; Histidine; Isoleucine; Leucine; Lysine; Methionine; Myocardium; Phenylalanine; Protein Binding; Protein Biosynthesis; Rats; Serine; Taurine; Tryptophan; Tyrosine; Valine | 1971 |
Amino acid levels in plasma, liver, muscle, and kidney during and after exercise in fasted and fed rats.
Topics: Acidosis; Alanine; Amino Acids; Animals; Aspartic Acid; Fasting; Gluconeogenesis; Glutamates; Glutaminase; Glutamine; Glycine; Kidney; Liver; Lysine; Male; Muscles; Physical Exertion; Rats; Serine; Swimming | 1971 |
Serine transhydroxymethylase. Affinity of the active site for substrates, substrate analogues, and anions.
Topics: Alanine; Aldehydes; Aminoisobutyric Acids; Animals; Benzoates; Binding Sites; Chlorides; Cysteamine; Cysteine; Electrophoresis; Folic Acid; Glycine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Models, Biological; Organophosphonates; Phosphates; Potassium; Propionates; Pyridoxal Phosphate; Rabbits; Serine; Spectrophotometry; Stereoisomerism; Sulfates; Sulfhydryl Compounds; Sulfonic Acids; Thermodynamics; Threonine; Transferases; Ultracentrifugation | 1971 |
The uptake of various amino acids by the mouse brain in vivo.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Biological Transport; Brain; Glycine; Histidine; Isoleucine; Methionine; Mice; Serine; Threonine; Time Factors; Tryptophan; Valine | 1971 |
The influence of various -alkyl and -hydroxyalkyl substituents on the stability of dipeptides in dilute alkali.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Borates; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Dipeptides; Drug Stability; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Isomerism; Kinetics; Leucine; Potassium; Serine; Stereoisomerism; Threonine; Valine | 1971 |
Essential amino acids in the culture of Leishmania tarentolae.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Culture Media; Glucose; Glutamates; Glycine; Histidine; Leishmania; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Chain amino termini of the cat hemoglobins and the response to 2,3-diphosphoglycerate and adenosine triphosphate.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Cats; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis; Erythrocytes; Glycerophosphates; Glycine; Hemoglobins; Humans; Hydrogen-Ion Concentration; Macromolecular Substances; Oxygen; Peptides; Phosphates; Protein Binding; Serine; Temperature; Trypsin | 1971 |
Biosynthesis of the formycin family.
Topics: Adenine; Adenine Nucleotides; Anti-Bacterial Agents; Aspartic Acid; Carbon Isotopes; Formates; Glutamates; Glycine; Nocardia; Orotic Acid; Ribose; RNA, Bacterial; Serine; Uracil | 1971 |
Vitamin B12 deficiency in the rat fed high protein rations.
Topics: Amino Acids; Animals; Caseins; Depression, Chemical; Dietary Proteins; Formates; Glycine; Growth; Isoleucine; Male; Malonates; Nitrogen; Proline; Propionates; Rats; Serine; Stereoisomerism; Threonine; Valine; Vitamin B 12; Vitamin B 12 Deficiency | 1971 |
The free amino acid concentrations in maternal and foetal plasmas in the pregnant ewe.
Topics: Alanine; Amino Acids; Animals; Chromatography, Ion Exchange; Female; Fetus; Glycine; Maternal-Fetal Exchange; Pregnancy; Pregnancy, Animal; Serine; Sheep; Threonine; Umbilical Arteries; Umbilical Veins | 1971 |
[Free amino acids and other ninhydrin-positive substances in the normal horny layer and in psoriasis scales].
Topics: Alanine; Amino Acids; Ammonia; Asparagine; Chromatography; Citrulline; Cysteine; Glycine; Histidine; Humans; Imidazoles; Phenylalanine; Proline; Psoriasis; Serine; Skin; Taurine; Threonine; Urea | 1967 |
[Chemistry of the antibiotic A-128 (neotelomycin)--qualitative and quantitative amino acid composition].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Aspartic Acid; Chemistry Techniques, Analytical; Chromatography, Paper; Electrophoresis; Glycine; Proline; Serine; Threonine; Tryptophan | 1967 |
[Differentiation of aliphatic dipeptidases from cod muscle].
Topics: Animals; Cellulose; Chromatography, Ion Exchange; Dipeptidases; Dipeptides; Fishes; Glycine; Hot Temperature; Kinetics; Leucine; Methionine; Muscles; Phenylalanine; Protein Denaturation; Serine; Spectrophotometry; Threonine; Valine; Zinc | 1967 |
[On amino acid exchange in the constant part of a lambda-type Bence Jones protein].
Topics: Amino Acid Sequence; Bence Jones Protein; Glycine; Peptides; Serine | 1967 |
[Quantitative paper chromatography amino acid determination. Stanardization of the procedure and method of testing of new paper types].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography, Paper; Cysteine; Glutamates; Glycine; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Methods; Paper; Phenylalanine; Serine; Spectrum Analysis; Sulfones; Threonine; Tyrosine; Ultraviolet Rays; Valine | 1967 |
On methylamine assimilation in a bacterium.
Topics: Amines; Aspartic Acid; Bacteria; Bicarbonates; Carbon Isotopes; Glycine; Malates; Serine | 1967 |
[Isoacceptor transfer RNA of rabbit reticulocytes].
Topics: Animals; Carbon Isotopes; Chromatography; Glycine; Methionine; Phenylalanine; Rabbits; Reticulocytes; RNA, Transfer; Serine; Sulfur Isotopes | 1967 |
[Studies on the physicochemical properties of basic protein of the brain].
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Chemical Phenomena; Chemistry; Chromatography, Gel; Electrophoresis, Disc; Glutamates; Glycine; Hydrogen-Ion Concentration; Leucine; Molecular Weight; Nerve Tissue Proteins; Serine; Ultracentrifugation; Valine | 1967 |
Amino acid requirements for growth of the rabbit blastocyst in vitro.
Topics: Amino Acids; Animals; Arginine; Culture Media; Female; Glycine; Histidine; In Vitro Techniques; Leucine; Lysine; Methionine; Ovum; Phenylalanine; Rabbits; Serine; Threonine; Tryptophan; Valine | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
N-Terminal acetyl-peptides from two calf thymus histones.
Topics: Animals; Arginine; Autoanalysis; Cattle; Chemical Phenomena; Chemistry, Physical; Chromatography, Ion Exchange; Glycine; Histones; Ion Exchange Resins; Peptides; Serine; Thymus Gland | 1968 |
The synthesis of one-carbon units from CO2 in Clostridium kluyveri.
Topics: Acetates; Adenine; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Clostridium; Ethanol; Formates; Glycerol; Glycine; Guanine; Histidine; Methionine; Ribose; Serine; Thymine | 1968 |
Dipeptidyl arylamidase II of the pituitary. Properties of lysylalanyl-beta-naphthylamide hydrolysis: inhibition by cations, distribution in tissues, and subcellular localization.
Topics: Acid Phosphatase; Alanine; Animals; Arginine; Cattle; Centrifugation, Density Gradient; Chromatography, Paper; Cytoplasm; Dipeptides; Endopeptidases; Glycine; Hydrogen-Ion Concentration; Kidney; Kinetics; Leucine; Lithium; Lysine; Lysosomes; Methionine; Naphthalenes; Nucleosides; Pituitary Gland; Potassium; Proline; Protease Inhibitors; Puromycin; Rats; Serine; Sodium; Spleen; Thyroid Gland; Tromethamine; Tyrosine | 1968 |
Secretion of amino acids in dog parotid saliva.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Carbon Isotopes; Cell-Free System; Dogs; Glycine; Infusions, Parenteral; Parotid Gland; Phenylalanine; Proline; Proteins; Saliva; Salivary Glands; Serine | 1968 |
Influence of cortisol on the utilization of precursors of nucleic acids and protein by lymphoid cells in vitro.
Topics: Adrenal Glands; Adrenalectomy; Aminoisobutyric Acids; Animals; Carbon Isotopes; Cold Temperature; Cycloparaffins; DNA; Glucose; Glycine; Hydrocortisone; In Vitro Techniques; Leucine; Lymph Nodes; Lymphoid Tissue; Male; Mesentery; Nucleic Acids; Phenylalanine; Protein Biosynthesis; Rabbits; Rats; RNA; Serine; Thymidine; Thymus Gland; Tissue Extracts; Tritium; Uridine | 1968 |
Purification and properties of an anionic zymogen of phospholipase A from porcine pancreas.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Autolysis; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis; Electrophoresis, Disc; Enzyme Precursors; Glutamates; Glycine; Isoflurophate; Isoleucine; Molecular Weight; Pancreas; Peptide Hydrolases; Peptides; Phospholipases; Serine; Swine; Trypsin | 1968 |
A model for sulfhydryl groups in proteins. Hydrophobic interactions of the cystein side chain in micelles.
Topics: Alkanes; Amides; Binding Sites; Chemical Phenomena; Chemistry; Coloring Agents; Cysteine; Glycine; Methods; Models, Chemical; Proteins; Serine; Spectrophotometry; Sulfhydryl Compounds | 1968 |
Studies on hyaluronic acid. II. The protein component(s) of rooster comb hyaluronic acid.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Autoanalysis; Chemical Phenomena; Chemistry; Chickens; Chromatography, Ion Exchange; Comb and Wattles; Glutamates; Glycine; Hyaluronic Acid; Male; Serine; Uronic Acids; Viscosity | 1968 |
The erythrocyte plasma distribution of amino acids in health and disease.
Topics: Acute Disease; Adolescent; Adult; Alanine; Amino Acids; Anemia, Hemolytic; Anemia, Pernicious; Bronchitis; Bronchopneumonia; Chromatography, Paper; Erythrocytes; Female; Glutamates; Glutamine; Glycine; Hepatitis; Humans; Hyperthyroidism; Infections; Inflammation; Isoleucine; Leucine; Male; Methionine; Neoplasms; Plasma; Pyelitis; Serine; Threonine; Valine | 1968 |
[On a new carboxypeptidase (EC 3.4.2.?) from spleen].
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Carboxypeptidases; Cattle; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Glutamates; Glycine; Kinetics; Leucine; Peptides; Serine; Spleen; Tyrosine; Valine | 1968 |
A major attachment site for D-serine in the cell wall mucopeptide of Micrococcus lysodeikticus.
Topics: Amino Acid Sequence; Cell Wall; Chromatography, Thin Layer; Culture Media; Glutamates; Glycine; Micrococcus; Mucoproteins; Peptides; Serine; Stereoisomerism | 1968 |
Effect of glutamine on inhibition of rat growth by glycine and serine.
Topics: Animals; Autoanalysis; Glutamine; Glycine; Growth; Male; Nitrogen; Rats; Serine | 1968 |
Effects of arginine or serine on the requirement for glycine by the chick.
Topics: Animals; Arginine; Body Weight; Chickens; Glycine; Serine | 1968 |
The molecular structures of vertebrate skin collagens. A comparative study.
Topics: Amino Acids; Animals; Anura; Arginine; Autoanalysis; Biological Evolution; Cattle; Chemical Phenomena; Chemistry, Physical; Chickens; Chromatography; Collagen; Electrophoresis; Fishes; Glutamates; Glycine; Guinea Pigs; Hydrogen-Ion Concentration; Hydroxyproline; Isoleucine; Leucine; Methionine; Optical Rotatory Dispersion; Proline; Serine; Sharks; Skin; Snakes; Solubility; Temperature; Threonine; Valine | 1968 |
Isolation and identification of alpha-amino aldehydes in collagen.
Topics: Air Sacs; Alanine; Aldehydes; Amino Alcohols; Animals; Aspartic Acid; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Thin Layer; Collagen; Cyprinidae; Gelatin; Glycine; Hydrazones; Lactones; Lysine; Oxidation-Reduction; Rats; Serine; Skin; Spectrum Analysis; Threonine; Tritium | 1968 |
Studies on the enzymic N-acylation of amino sugars in the sheep colonic mucosa.
Topics: Acetates; Amino Sugars; Animals; Carbon Isotopes; Colon; Fucose; Galactose; Glucosamine; Glucose; Glycine; Hexosamines; In Vitro Techniques; Intestinal Mucosa; Neuraminic Acids; Pyruvates; Serine; Sheep | 1968 |
The distribution of amino acids between erythrocytes and plasma in fetal and maternal blood.
Topics: Alanine; Amino Acids; Biological Transport, Active; Chromatography, Paper; Erythrocytes; Female; Glutamates; Glutamine; Glycine; Humans; Infant, Newborn; Isoleucine; Leucine; Maternal-Fetal Exchange; Methionine; Placenta; Plasma; Pregnancy; Serine; Threonine; Valine | 1968 |
Some effects of amino acid deficiencies on antibody formation in the rat.
Topics: Amino Acids; Animals; Antibody Formation; Antigens; Antimetabolites; Body Weight; Deficiency Diseases; Diet; Digestive System; Ethionine; Germ-Free Life; Glycine; Hemagglutination Tests; Male; Methionine; Phenylalanine; Rats; Serine; Sheep; Tryptophan; Vitamin B 6 Deficiency | 1968 |
[Purification of arginine tRNA 3 from brewer's yeast].
Topics: Arginine; Cellulose; Chromatography; Countercurrent Distribution; Glycine; Hydroxyapatites; Leucine; Lysine; Methionine; RNA, Transfer; Saccharomyces; Serine; Tryptophan | 1968 |
Metabolism of glycine in the nonketotic form of hyperglycinemia.
Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Carbon Dioxide; Carbon Isotopes; Child; Child, Preschool; Glycine; Humans; Injections, Intravenous; Male; Serine | 1968 |
Biosynthesis of kasugamycin. II. Biosynthesis of the two-carbon-side chain of kasugamycin.
Topics: Anti-Bacterial Agents; Carbon Isotopes; Chemical Phenomena; Chemistry; Electrophoresis; Glucose; Glycine; Glyoxylates; Inositol; Maltose; Mannose; Oxalates; Pyruvates; Serine; Streptomyces | 1968 |
A study of 2,4,6-trinitrobenzenesulfonic acid for automated amino acid chromatography.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Autoanalysis; Chromatography; Cystine; Glycine; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Isoleucine; Leucine; Lysine; Methionine; Methods; Nitrobenzenes; Phenylalanine; Proline; Serine; Spectrophotometry; Sulfonic Acids; Temperature; Threonine; Tryptophan; Tyrosine; Urea; Valine | 1968 |
Primary structure of insoluble tendon collagen. 3. Analysis of products of tryptic digestion of native collagen.
Topics: Achilles Tendon; Alanine; Aldehydes; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cysteine; Electrophoresis; Glutamine; Glycine; Hexosamines; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Proline; Serine; Sulfur; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Trace metal requirements for malformin biosynthesis.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Aspartic Acid; Aspergillus; Chromium; Cobalt; Copper; Cysteine; Glutamine; Glycine; Histidine; Iron; Isoleucine; Leucine; Lysine; Manganese; Metals; Molybdenum; Peptide Biosynthesis; Phenylalanine; Plant Growth Regulators; Proline; Serine; Trace Elements; Tryptophan; Tyrosine; Valine; Zinc | 1968 |
[Separation of low molecular weight ninhydrine positive substances in pleural punctates. Contribution to the problem of inflammation].
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Chromatography; Chromatography, Gel; Electrophoresis; Glutamates; Glycine; Inflammation; Lysine; Paper; Peptides; Pleural Effusion; Rabbits; Serine; Trypan Blue; Valine | 1968 |
Biosynthesis of thiamine. Incorporation experiments with 14C-labelled substrates and with (15N)glycine in Saccharomyces cerevisiae.
Topics: Acetates; Carbon Isotopes; Formates; Glycine; Methionine; Nitrogen; Pyrimidines; Radioisotopes; Saccharomyces; Serine; Thiamine; Thiazoles | 1968 |
Species specificity of the conformation of silk fibroin in solution.
Topics: Alanine; Alcohols; Amino Acid Sequence; Amino Acids; Animals; Bombyx; Chemical Phenomena; Chemistry; Dioxins; Fibroins; Glycine; Infrared Rays; Insecta; Optical Rotatory Dispersion; Serine; Solubility; Species Specificity; Spectrum Analysis | 1968 |
Biosynthesis of bacitracin. II. Incorporation of 14C-labeled amino acids into bacitracin by a cell-free preparation from Bacillus licheniformis.
Topics: Adenosine Triphosphate; Amino Acids; Asparagine; Bacillus; Bacitracin; Bacteriolysis; Carbon Isotopes; Cell-Free System; Chloramphenicol; Chromatography, Paper; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Magnesium; Ornithine; Peptide Biosynthesis; Phenylalanine; Puromycin; Ribonucleases; Serine; Time Factors | 1968 |
Optical configuration of staphylococcal cell wall serine.
Topics: Biological Assay; Cell Wall; Chemical Phenomena; Chemistry, Physical; Glycine; Serine; Staphylococcus; Streptococcus | 1968 |
[Intermediate products in the synthesis of compounds in the lycomarasin series from glycine and 1-serine].
Topics: Anti-Bacterial Agents; Glycine; Serine | 1968 |
Structural analysis of the glycine-rich, arginine-rich histone. I. Sequence of the carbosyl-terminal portion.
Topics: Amino Acid Sequence; Animals; Arginine; Aspartic Acid; Bromine; Carboxypeptidases; Cattle; Chromatography, Gel; Chymotrypsin; Cyanides; Electrophoresis; Glycine; Histones; Peptides; Phenylalanine; Serine; Thymus Gland; Trypsin; Tyrosine | 1968 |
Calf and pea histone IV. I. Amino acid compositions and the identical COOH-terminal 19-residue sequence.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Evolution; Bromine; Cattle; Chromatography, Gel; Chymotrypsin; Cyanides; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Plants; Proline; Serine; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Serine transhydroxymethylase. Identification as the threonine and allothreonine aldolases.
Topics: Acetaldehyde; Aldehyde-Lyases; Amino Acids; Animals; Carbon Isotopes; Chemical Precipitation; Chromatography; Chromatography, Gel; Glycine; Hot Temperature; Liver; Methods; Protein Denaturation; Rabbits; Serine; Threonine; Transferases | 1968 |
Two procedures for accelerated separation of amino acids by column chromatography.
Topics: Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Buffers; Chromatography, Ion Exchange; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Methods; Phenylalanine; Proline; Serine; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Naturally occurring low-molecular-weight peptides from the blowfly Phormia regina.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Dipeptides; Diptera; Glutamine; Glycine; Isoleucine; Lysine; Peptides; Serine; Valine | 1968 |
Serine transhydroxymethylase in developing mouse brain.
Topics: Age Factors; Animals; Animals, Newborn; Brain; Carbon Isotopes; Folic Acid; Formaldehyde; Glycine; Mice; Pyridoxal Phosphate; Serine; Tissue Extracts; Transferases | 1968 |
[On the influence of the starting position on migration of substances in paper electrophoresis].
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Asparagine; Cysteine; Electrophoresis; Glucose; Glutamates; Glutamine; Glycine; Histidine; Leucine; Lysine; Methionine; Serine; Serum Albumin; Taurine; Tryptophan | 1968 |
States of amino acid residues in proteins. XVI. Naphthoquinones with two sulfonic groups as a reagent for discrimation of amino groups in proteins.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chymotrypsin; Colorimetry; Freezing; Glycine; Histidine; Hydrogen-Ion Concentration; Imidazoles; Indicators and Reagents; Insulin; Lysine; Muramidase; Naphthoquinones; Proline; Proteins; Ribonucleases; Serine; Spectrophotometry; Sulfonic Acids; Tryptophan; Tyrosine | 1968 |
Conversion of serine to glycine in the spinning larvae of silkworm, Bombyx mori.
Topics: Animals; Bombyx; Carbon Isotopes; Glycine; Serine | 1968 |
[Studies on glycoproteins. XXV. The C-terminal amino acids of human transferrin and lactotransferrin].
Topics: Amino Acids; Autoanalysis; Chromatography, Ion Exchange; Glycine; Glycoproteins; Humans; Lactoglobulins; Peptides; Proline; Serine; Transferrin | 1968 |
Amino acid binding to luteinizing hormone.
Topics: Acetates; Alanine; Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Cellulose; Chromatography, Gel; Countercurrent Distribution; Electrophoresis; Glycine; Glycoproteins; Guanidines; Luteinizing Hormone; Peptides; Protein Binding; Serine; Sheep; Threonine | 1968 |
Side reactions in the synthesis of peptides containing the aspartyglycyl sequence.
Topics: Aspartic Acid; Chemical Phenomena; Chemistry; Glycine; Heterocyclic Compounds; Histidine; Imides; Peptides; Phenylalanine; Serine; Succinates; Threonine | 1968 |
[An after-effect in x-ray irradiated aqueous solutions of lysine and other aliphatic amino acids].
Topics: 1-Propanol; Alanine; Amino Acids; Aminobutyrates; Butylamines; Butyrates; Glycine; Heterocyclic Compounds; Lysine; Propionates; Radiation Effects; Radiochemistry; Serine; Solutions; Spectrophotometry | 1968 |
[The free amino acids in a water-soluble superficial film of the skin in exanthematous diseases in childhood].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chickenpox; Child; Chromatography, Paper; Female; Glutamine; Glycine; Histidine; Humans; Leucine; Male; Measles; Rubella; Scarlet Fever; Serine; Sweat; Valine | 1968 |
The glycine-serine interrelationship in chick nutrition.
Topics: Animal Nutritional Physiological Phenomena; Animals; Chickens; Glycine; Male; Serine | 1968 |
[Incorporation of 14C-proline into ripening wheat].
Topics: Asparagine; Carbon Isotopes; Chromatography, Thin Layer; Glycine; Peptides; Plant Proteins; Proline; Serine; Threonine; Triticum | 1968 |
Amino acids involved in chromophore-protein linkages in phycoerythrins.
Topics: Alanine; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glycine; Pigments, Biological; Proteins; Serine; Threonine | 1968 |
Amino acid flux in an estuary.
Topics: Amino Acids; Glycine; Kinetics; Ornithine; Photosynthesis; Plankton; Serine; Virginia; Water | 1968 |
[Levels of free amino acids in the blood and heart muscle in the human at various periods of myocardial infarct (clinical anatomical parallels)].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Erythrocytes; Glutamates; Glycine; Histidine; Histocytochemistry; Humans; Isoleucine; Leucine; Lysine; Methods; Middle Aged; Myocardial Infarction; Myocardium; Necrosis; Phenylalanine; Serine; Threonine; Time Factors; Tyrosine; Valine | 1968 |
[Isolation and identification of a ninhydrin-positive complex from the brain under the effect of gamma-amino butyric acid].
Topics: Amino Acids; Aminobutyrates; Animals; Brain Chemistry; Carotid Arteries; Dogs; Drug Stability; Glycine; Indicators and Reagents; Injections, Intra-Arterial; Serine; Stimulation, Chemical; Threonine; Time Factors; Tyrosine | 1968 |
Number of polypeptide components in bacteriophage T2L contractile sheaths.
Topics: Alanine; Amino Acids; Aspartic Acid; Carboxypeptidases; Coliphages; Glutamine; Glycine; Hydrazines; Leucine; Peptides; Serine; Threonine; Tryptophan; Valine | 1968 |
[Crystalline leucine aminopeptidase from bovine lens. Amino acid composition and N-terminal amino acids, II].
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Cattle; Crystallography; Formates; Glutamates; Glutamine; Glycine; Lens, Crystalline; Leucine; Leucyl Aminopeptidase; Lysine; Serine; Threonine | 1968 |
Piperonylic acid conjugates with alanine, glutamate, glutamine, glycine, and serine in living houseflies.
Topics: Alanine; Amino Acids; Animals; Benzoates; Dioxoles; Female; Glutamates; Glutamine; Glycine; Houseflies; Serine | 1968 |
Quinoxaline studies. XIV. Potential anticancer agents. Some quinoxaline amino acid and dipeptide derivatives related to quinoxaline antibiotics.
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Dipeptides; Glycine; Leukemia L1210; Methionine; Mice; Quinoxalines; Serine; Valine | 1969 |
Studies on wheat plants using 14C-labelled compounds. XXII. Incorporation into wheat protein.
Topics: Amino Acids; Arginine; Aspartic Acid; Carbon Dioxide; Chromatography, Ion Exchange; Citric Acid Cycle; Glutamates; Glutamine; Glutens; Glycine; Glyoxylates; Plant Proteins; Proline; Seeds; Serine; Succinates; Triticum | 1969 |
Beta-cyanoalanine formation by Chromobacterium violaceum.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; Carbon Isotopes; Chromobacterium; Cyanides; Formaldehyde; Glycine; Methionine; Serine; Succinates | 1969 |
Determination of dinitrophenylamino acids in structural proteins by chromatography on nylon powder columns. II. The ether-soluble dinitrophenylamino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography; Dinitrophenols; Glutamates; Glycine; Hydrogen-Ion Concentration; Methods; Nylons; Proteins; Serine; Threonine; Valine | 1969 |
Glycin metabolism by rat liver mitochondria. I. Synthesis of two molecules of glycine from one molecule each of serine, bicarbonate and ammonia.
Topics: Air; Ammonia; Animals; Bicarbonates; Carbon; Carbon Isotopes; Glycine; In Vitro Techniques; Mitochondria, Liver; Nitrogen; Nucleosides; Rats; Serine | 1969 |
[Modification of lipid metabolism with solvosterol].
Topics: Aged; Alanine; Arteriosclerosis; Cholesterol; Colorimetry; Glycine; Humans; Injections, Intramuscular; Isoleucine; Lipids; Lipoproteins; Male; Serine; Valine | 1969 |
Mechanism of autolysis of isolated cell walls of Staphylococcus aureus.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Bacteriolysis; Cell Wall; Chromatography, Gel; Chromatography, Ion Exchange; Glucosamine; Glutamates; Glycine; Hexosamines; Serine; Staphylococcus | 1969 |
Papaya lysozyme. Terminal sequences and enzymatic properties.
Topics: Amino Acid Sequence; Bacteria; Binding Sites; Carboxypeptidases; Cell Wall; Chitinases; Glycine; Histamine; Histidine; Hot Temperature; Hydrogen-Ion Concentration; Isoleucine; Lysine; Muramidase; Phenylalanine; Plants; Serine; Tryptophan | 1969 |
Formation and spectral properties of copper (II) ion complexes of the NH2-terminal pentapeptide from sperm whale myoglobin and of certain tetra- and pentapeptides.
Topics: Alanine; Amino Acids; Animals; Cetacea; Chemical Phenomena; Chemistry; Chromatography, Paper; Copper; Glutamates; Glycine; Histidine; Leucine; Light; Myoglobin; Peptides; Potentiometry; Rotation; Serine; Spectrophotometry; Spectrum Analysis; Stereoisomerism; Valine | 1969 |
Studies on the structure and function of muscle aldolase. IV. The action of dilute alkali on primary structure and its effect on the determination of subunit molecular weight.
Topics: Aldehyde-Lyases; Alkalies; Animals; Boron Compounds; Buffers; Carboxypeptidases; Chemical Phenomena; Chemistry; Computers; Electrophoresis; Electrophoresis, Disc; Glycine; Hexosephosphates; Hydrogen-Ion Concentration; Molecular Weight; Muscles; Peptides; Proline; Rabbits; Serine; Solubility; Succinates; Temperature; Threonine; Time Factors; Ultracentrifugation | 1969 |
Isolation and characterization of alkaline proteinase of Aspergillus flavus.
Topics: Alanine; Amino Acids; Aspergillus; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Disc; Glycine; Isoflurophate; Molecular Weight; Peptide Hydrolases; Phosphorus Isotopes; Serine; Ultracentrifugation | 1969 |
Amino-acid receptor in larvae of Pieris brassicae (Lepidoptera).
Topics: Action Potentials; Amino Acids; Aminobutyrates; Animals; Chemoreceptor Cells; Cysteine; Glutamates; Glycine; Insecta; Leucine; Methionine; Proline; Serine; Stimulation, Chemical | 1969 |
Serine transhydroxymethylase in methionine biosynthesis in Saccharomyces cerevisiae.
Topics: Cell-Free System; Enzyme Repression; Glycine; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Methionine; Methylation; Saccharomyces; Serine; Transferases | 1969 |
Effect of glucagon on concentration of several free amino acids in plasma.
Topics: Alanine; Amino Acids; Arginine; Citrulline; Cystine; Depression, Chemical; Fasting; Female; Glucagon; Glycine; Histidine; Humans; Leucine; Liver; Lysine; Male; Methionine; Nitrogen; Phenylalanine; Progesterone; Proline; Serine; Threonine; Tyrosine; Valine | 1969 |
A study of transfer ribonucleic acid in Neurospora. I. The attachment of amino acids and amino acid analogs.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Carbon Isotopes; Chromatography, Ion Exchange; Ethionine; Glutamates; Glutamine; Glycine; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methionine; Neurospora; Phenylalanine; Phosphates; RNA, Transfer; Serine; Sulfhydryl Compounds; Time Factors; Tritium | 1969 |
Gas-liquid chromatography of radioactive amino acids as their trifluoroacetyl ester derivatives.
Topics: Amino Acids; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gas; Esters; Glutamates; Glycine; Hydroxyproline; Isoleucine; Leucine; Methods; Phenylalanine; Serine; Threonine | 1969 |
Dietary effects on the need for glycine by the chick.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Chickens; Diet; Glycine; Growth; Liver; Serine; Transferases | 1969 |
Circadian periodicity of blood amino acids in normal and adrenalectomized mice.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Circadian Rhythm; Cystine; Densitometry; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Mice; Serine; Threonine; Tryptophan; Tryptophan Oxygenase; Tyrosine; Valine | 1969 |
Structures of the cell wall peptidoglycans of Staphylococcus epidermidis Texas 26 and Staphylococcus aureus Copenhagen. I. Chain length and average sequence of cross-bridge peptides.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Cell Wall; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Glycerophosphates; Glycine; Hexosamines; Lysine; Pentosephosphates; Peptides; Polysaccharides, Bacterial; Serine; Species Specificity; Staphylococcus | 1969 |
Structures of the cell wall peptidoglycans of Staphylococcus epidermidis Texas 26 and Staphylococcus aureus Copenhagen. II. Structure of neutral and basic peptides from hydrolysis with the Myxobacter al-1 peptidase.
Topics: Amino Acids; Bacteria; Cell Wall; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Glycine; Hexosamines; Hydrogen-Ion Concentration; Kinetics; Models, Biological; Peptide Biosynthesis; Peptide Hydrolases; Peptides; Polysaccharides, Bacterial; Serine; Species Specificity; Staphylococcus | 1969 |
Physiological significance of glycine cleavage system in human liver as revealed by the study of a case of hyperglycinemia.
Topics: Adult; Carbon Dioxide; Carbon Isotopes; Female; Folic Acid; Glycine; Humans; Infant; L-Serine Dehydratase; Liver; Metabolism, Inborn Errors; Serine; Transferases | 1969 |
Amino acid feeding studies: effects of various nonessential nitrogen sources and of added water.
Topics: Alanine; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Aspartic Acid; Body Weight; Diet; Glutamates; Glycine; Male; Nitrogen; Proline; Rats; Serine | 1969 |
Urinary amino acid and peptide excretion patterns in patients with muscular dystrophy (Duchenne). A preliminary study with the autoanalyzer.
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Autoanalysis; Child; Child, Preschool; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Muscular Dystrophies; Peptides; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1969 |
The mitochondrial and cytoplasmic transfer ribonucleic acids of Neurospora crassa.
Topics: Amino Acids; Carbon Isotopes; Centrifugation, Zonal; Chromatography; Countercurrent Distribution; Cytoplasm; Glutamates; Glutamine; Glycine; Leucine; Ligases; Lysine; Methionine; Mitochondria; Neurospora; Phenylalanine; RNA, Transfer; Serine; Tritium | 1969 |
Use of respiration pattern analysis for study of serine metabolism in vivo.
Topics: Animals; Carbon Dioxide; Fasting; Female; Formates; Glycine; Male; Mice; Respiration; Serine | 1969 |
Local solvent structure as a factor in secondary isotope fractionation phenomena of labeled amino acids on ion-exchange columns.
Topics: Alcohols; Amino Acids; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Glutamates; Glycine; Phenylalanine; Proline; Serine; Solvents; Tritium; Tyrosine | 1969 |
Subunit structure and chemical properties of rabbit liver aldolase.
Topics: Amino Acids; Animals; Carboxypeptidases; Chromatography, Gel; Detergents; Electrophoresis, Disc; Fructose-Bisphosphate Aldolase; Glycine; Guanidines; Hydrazines; Liver; Methionine; Methods; Molecular Weight; Muscles; Organ Specificity; Rabbits; Serine; Sulfates; Tyrosine; Ultracentrifugation | 1969 |
Typical hyperaminoaciduria after high doses of 6-azauridine triacetate.
Topics: Acetates; Adult; Alanine; Amino Acids; Chromatography, Paper; Glycine; Humans; Middle Aged; Psoriasis; Serine; Triazines; Urine | 1969 |
[Studies on the metabolism of glycerol in the central nervous system. I. Incorporation of glycerol carbon into the free amino acids of mouse brain].
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Carbon Isotopes; Glucose; Glutamates; Glutamine; Glycerol; Glycine; Male; Mice; Serine | 1969 |
Metabolism of glyoxylate in nonketotic hyperglycinemia.
Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Carbon Dioxide; Carbon Isotopes; Child; Child, Preschool; Female; Glycine; Glyoxylates; Humans; Male; Oxalates; Serine | 1969 |
[Studies on the amino acid composition of some African legumes].
Topics: Amino Acids; Arginine; Aspartic Acid; Canavanine; Chromatography; Cystine; Food Analysis; Glutamine; Glycine; Histidine; Hot Temperature; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Plants, Edible; Proline; Proteins; Serine; Threonine; Tryptophan; Tyrosine; Valine; Vegetables | 1969 |
Glycine-producing transaminase activity in extracts of spinal cord.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Carbon Isotopes; Cats; Chromatography, Paper; Cystine; Glutamates; Glutamine; Glycine; Glyoxylates; Rats; Serine; Spinal Cord; Tissue Extracts; Transaminases | 1969 |
Studies on the biosynthesis of lincomycin. IV. The origin of methyl groups.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Glycine; Lincomycin; Methionine; Methylation; Serine; Spectrum Analysis; Streptomyces | 1969 |
Biosynthesis of thiamin. IV. C-2 of glycine as the precursor of C-2 of the thiazole moiety in yeast.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Formaldehyde; Formates; Glycine; Methionine; Models, Biological; Saccharomyces; Serine; Sulfonic Acids; Thiamine; Thiazoles | 1969 |
Reversal of the growth inhibitory action of glycine and glycylglycine by alanylalanine in Mycobacterium smegmatis.
Topics: Alanine; Amino Sugars; Chromatography, Paper; Depression, Chemical; Dipeptides; Glycine; Mycobacterium; Serine; Spectrophotometry; Stereoisomerism; Stimulation, Chemical; Ultraviolet Rays | 1969 |
Amino acid analysis of glycine-extracted deoxyribonucleoproteins (sea urchin sperm).
Topics: Amino Acids; Animals; Arginine; DNA; Echinodermata; Electrophoresis; Glycine; Lysine; Male; Nucleoproteins; Nucleotides; Purines; Pyrimidines; Serine; Spermatozoa; Threonine; Valine | 1969 |
Histones in early embryogenesis.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Echinodermata; Electrophoresis; Embryo, Nonmammalian; Fishes; Gels; Genetic Code; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
Mental retardation, abnormal hair and mild aminoaciduria, all of unknown aetiology, in siblings.
Topics: Alanine; Child, Preschool; Female; Fluoroscopy; Glutamine; Glycine; Hair; Humans; Intellectual Disability; Male; Renal Aminoacidurias; Serine; Taurine | 1969 |
Isolation of a glycopeptide from a 7S protein in soybean globulins.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Globulins; Glucosamine; Glutamates; Glycine; Glycine max; Glycoproteins; Mannose; Molecular Weight; Monosaccharides; Polysaccharides; Serine; Threonine | 1969 |
Conversion of serine to glycine during the formation of egg-shells in the silkworm, bombyx mori.
Topics: Bombyx; Female; Glycine; Ovum; Serine | 1969 |
The inhibition of activated Factor X with di: isopropyl fluorophosphate.
Topics: Amino Acids; Animals; Aspartic Acid; Cattle; Chromatography, Thin Layer; Electrophoresis; Esterases; Factor X; Glycine; Isoflurophate; Peptides; Phosphorus Isotopes; Serine | 1969 |
The specificity of purified porcine pancreatic elastase.
Topics: Alanine; Animals; Chromatography; Cysteine; Electrophoresis; Glutamates; Glycine; Histidine; Insulin; Leucine; Pancreas; Pancreatic Elastase; Phenylalanine; Serine; Swine; Valine | 1969 |
Transfer RNA changes associated with early development and differentiation of the sea urchin, Stronglyocentrotus purpuratus.
Topics: Animals; Carbon Isotopes; Cell Differentiation; Chromatography; Echinodermata; Female; Germ Layers; Glycine; Leucine; Ligases; Lysine; Ovum; Phenylalanine; Protein Biosynthesis; RNA, Messenger; RNA, Transfer; Serine; Tritium | 1969 |
Effect of source of dietary nitrogen on plasma concentration and urinary excretion of amino acids of men.
Topics: Adult; Amino Acids; Arginine; Caseins; Citrates; Diet; Fasting; Glutamates; Glycine; Histidine; Humans; Male; Nitrogen; Proline; Quaternary Ammonium Compounds; Serine; Taurine; Threonine; Time Factors | 1969 |
Primary structure of two oligopeptides of the toxin of Bombina variegata L.
Topics: Amino Acid Sequence; Animals; Anura; Chromatography, Paper; Electrophoresis; Glycine; Peptides; Serine; Toxins, Biological | 1969 |
Glycine synthesis and isocitrate lyase in the nematode, Caenorhabditis briggsae.
Topics: Acetates; Alanine; Animals; Aspartic Acid; Chromatography, Paper; Dinitrophenols; Glycine; Hydrazines; In Vitro Techniques; Lyases; Nematoda; Serine | 1964 |
The metabolism of [14-C]glycine by plant tissues.
Topics: Carbon Dioxide; Chromatography, Paper; Formates; Glycine; Glyoxylates; In Vitro Techniques; Iodoacetates; Malonates; Plants, Toxic; Ricinus; Serine; Vegetables | 1964 |
Biosynthesis of insulin chains A and B.
Topics: Animals; Carbon Isotopes; Cysteine; Glycine; In Vitro Techniques; Insulin; Methylthiouracil; Pancreas; Radiometry; Rats; Serine; Sulfur Isotopes; Tyrosine | 1965 |
The utilization of carbon-1 compounds by plants. II. The formation and metabolism of formate by higher plant tissues.
Topics: Edible Grain; Formates; Glycine; Glyoxylates; Homocysteine; In Vitro Techniques; Methionine; Plants; Plants, Toxic; Ricinus; Serine; Zea mays | 1965 |
The labeling in vitro of glutathione of human blood cells.
Topics: Blood Cells; Cell Membrane Permeability; Cysteine; Cystine; Fluorides; Glucose; Glutathione; Glycine; Hemolysis; Humans; In Vitro Techniques; Phosphates; Plasma Substitutes; Serine; Sulfur Isotopes | 1965 |
Metabolism of amino acids in the lens.
Topics: Adenosine Triphosphate; Animals; Cattle; Crystallins; Glutathione; Glycine; In Vitro Techniques; Kinetics; Lactates; Lens, Crystalline; Puromycin; Serine; Valine | 1964 |
End product control of amino acid synthesis by cultured human cells.
Topics: Alanine; Arginine; Culture Techniques; Enzyme Repression; Glucose; Glutamine; Glycine; Humans; Methionine; Ornithine; Proline; Serine | 1965 |
Uric acid synthesis in the terrestrial snail, Otala lactea.
Topics: Animals; Autoradiography; Formates; Glucosyltransferases; Glycine; Gonads; Hypoxanthines; Imidazoles; In Vitro Techniques; Liver; Pancreas; Serine; Snails; Uric Acid | 1965 |
Cell division in a species of Erwinia. 8. Amino acid composition of the mucopeptide in dividing and non-dividing cells.
Topics: Amino Acids; Amino Sugars; Aspartic Acid; Cell Division; Erwinia; Glycine; In Vitro Techniques; Lactones; Peptide Biosynthesis; Serine | 1965 |
The incorporation pattern of glycine and serine on the biosynthesis of collagen and globin.
Topics: Animals; Blood Proteins; Bone Marrow; Bone Marrow Cells; Collagen; Dinitrophenols; Erythrocytes; Globins; Glycine; Guinea Pigs; In Vitro Techniques; Poultry; Rabbits; Serine | 1965 |
Stimulation of the binding of aminoacyl-sRNA to ribosomes by tubercidin (7-deazaadenosine) and N 6-dimethyladenosine containing trinucleoside diphosphate analogs.
Topics: Alanine; Anti-Bacterial Agents; Glutamates; Glycine; In Vitro Techniques; Lysine; Nucleotides; Proline; Ribosomes; RNA, Transfer; Serine; Threonine | 1965 |
Partial sequence of the first nine amino acids from the C-terminal end in bovine growth hormone.
Topics: Alanine; Amides; Amino Acid Sequence; Animals; Carboxypeptidases; Cattle; Chromatography, Paper; Glutamates; Glycine; Growth Hormone; In Vitro Techniques; Phenylalanine; Serine; Trypsin | 1965 |
Arginine and urea biosynthesis in the land planarian: its significance in biochemical evolution.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoradiography; Carbon Dioxide; Chromatography, Paper; Citrulline; Glutamates; Glutamine; Glycine; Serine; Succinates; Turbellaria; Urea | 1965 |
Biogenesis of ethylene in Penicillium digitatum.
Topics: Aminopterin; Betaine; Ethylenes; Glucose; Glycine; Glycolates; Penicillium; Quaternary Ammonium Compounds; Serine | 1965 |
[Investigations on the biosynthesis of glycine in Neurospora crassa, wild type and mutants].
Topics: Aspergillus; Carbon; Culture Media; Glycine; In Vitro Techniques; Mutation; Neurospora; Pyruvates; Serine; Transaminases | 1965 |
[Glutamate metabolism in rabbit renal cortex slices].
Topics: Alanine; Animals; Aspartic Acid; Autoradiography; Carbon Isotopes; Chromatography; Culture Techniques; Glucose; Glutamates; Glutamine; Glycine; Kidney; Rabbits; Serine | 1965 |
The determination of amino acids in 0.1 ml. of blood plasma.
Topics: Alanine; Amino Acids; Arginine; Blood Chemical Analysis; Chemistry, Clinical; Chromatography, Gel; Chromatography, Paper; Colorimetry; Densitometry; Glutamine; Glycine; Humans; In Vitro Techniques; Lysine; Microchemistry; Serine; Taurine; Threonine; Valine | 1966 |
The enzymatic synthesis of N-methylglutamic acid.
Topics: Alanine; Amines; Ammonia; Aspartic Acid; Autoradiography; Chromatography, Paper; Dialysis; Glutamate Dehydrogenase; Glutamates; Glycine; In Vitro Techniques; Pseudomonas; Serine; Soil Microbiology | 1966 |
Amino acids in seven species of cestodes.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cestoda; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Nitrogen; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
Studies on the origin of the methyl groups of choline in Ochromonas malhamensis.
Topics: Carbon Isotopes; Choline; Chromatography; Eukaryota; Formaldehyde; Formates; Glycine; Methane; Methionine; Serine; Tritium | 1966 |
Elevated cell wall serine in pleiotropic staphylococcal mutants.
Topics: Amino Acids; Autoanalysis; Carbohydrates; Cell Wall; Coagulase; Glycine; Lysine; Mannitol; Mutation; Serine; Staphylococcus | 1966 |
A defined medium for growth and pigment synthesis of Micrococcus roseus.
Topics: Adenine; Amines; Arginine; Culture Media; Fructose; Glutamates; Glycine; Isoleucine; Leucine; Lutein; Methionine; Mevalonic Acid; Micrococcus; Pigments, Biological; Proline; Salts; Serine; Spectrophotometry | 1966 |
Alterations in serine metabolism in rats fed liquid synthetic diets.
Topics: Alcohol Oxidoreductases; Animals; Cysteine; Diet; Glycerolphosphate Dehydrogenase; Glycine; Hydro-Lyases; Liver; Rats; Serine | 1966 |
Glycolate, glycine, serine, and glycerate formation during photosynthesis by tobacco leaves.
Topics: Carbon Dioxide; Carbon Isotopes; Glycerophosphates; Glycine; Glycolates; In Vitro Techniques; Nicotiana; Photosynthesis; Plants, Toxic; Propionates; Serine | 1966 |
Factors affecting transformation of Bacillus licheniformis.
Topics: Adenine; Arginine; Bacillus; Culture Media; DNA, Bacterial; Genes; Glycine; Histidine; In Vitro Techniques; Mutation; Serine | 1966 |
Amino acid compostion of walls from single and filamentous cells of Clostridium acidiurici.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacterial Proteins; Cell Wall; Chromatography; Clostridium; Glutamates; Glycine; In Vitro Techniques; Isomerases; Leucine; Lysine; Methionine; Oxidoreductases; Phenylalanine; Proline; Serine; Valine | 1966 |
Biochemical studies with the vinca alkaloids. II. Effect of vinblastine on the biosynthesis of nucleic acids and their precursors in rat thymus cells.
Topics: Adenine; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, Ion Exchange; DNA; Formates; Glutamine; Glycine; Guanine; Hypoxanthines; In Vitro Techniques; Rats; RNA; Serine; Spectrophotometry; Thymine; Thymus Gland; Vinblastine; Xanthines | 1966 |
The biosynthesis of hadacidin.
Topics: Amino Acids; Anti-Bacterial Agents; Antineoplastic Agents; Formates; Glycine; Glyoxylates; In Vitro Techniques; Oximes; Oxygen Isotopes; Penicillium; Serine | 1966 |
Fractionation of amino acid-specific s-RNA from silkgland by methylated albumin column chromatography.
Topics: Alanine; Albumins; Animals; Bombyx; Chemical Phenomena; Chemistry; Chemistry Techniques, Analytical; Chromatography; Glycine; In Vitro Techniques; Leucine; Lysine; Methionine; Phenylalanine; RNA, Transfer; Serine; Tyrosine | 1966 |
Modes of uptake of benzylamine by the Ehrlich cell.
Topics: Aminoisobutyric Acids; Aniline Compounds; Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Cocaine; Glycine; Hydrogen-Ion Concentration; In Vitro Techniques; Serine | 1966 |
Free amino acid pools in the developing sea urchin Lytechinus variegatus.
Topics: Alanine; Amino Acids; Animals; Echinodermata; Glycine; Serine | 1966 |
Isolation of amino acyl oligonucleotides from T-1 ribonuclease digests of soluble ribonucleic acid charged with serine, glycine, threonine, and alanine.
Topics: Alanine; Chromatography, Ion Exchange; Electrophoresis; Glycine; Nucleotides; Ribonucleases; RNA, Transfer; Saccharomyces; Serine; Threonine | 1966 |
On the synthesis of taurine from sulfate by the chick. I. Influential dietary factors.
Topics: Alanine; Amino Alcohols; Animals; Cysteine; Diet; Glycine; In Vitro Techniques; Kidney; Liver; Myocardium; Poultry; Pyruvates; Serine; Spleen; Sulfates; Sulfites; Taurine; Thiosulfates | 1966 |
A new reaction for glycine biosynthesis.
Topics: Ammonium Chloride; Animals; Bicarbonates; Glycine; In Vitro Techniques; Liver; Mitochondria; Rats; Serine | 1966 |
Polyamide layer chromatography of DNP-amino acids.
Topics: Alanine; Amides; Arginine; Aspartic Acid; Chromatography; Dinitrophenols; Glutamates; Glycine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
Changes in the concentration of free amino acids in the rat brain during postnatal development.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Animals, Newborn; Aspartic Acid; Brain; Female; Glutamates; Glutamine; Glutathione; Glycine; Male; Rats; Serine; Taurine | 1966 |
The metabolism of glycine and glycollate by pea leaves in relation to photosynthesis.
Topics: Carbon Dioxide; Glycine; Glycolates; Herbicides; In Vitro Techniques; Isoniazid; Partial Pressure; Photosynthesis; Plants, Edible; Serine | 1966 |
Water relations of Salmonella oranienburg; stimulation of respiration by amino acids.
Topics: Alanine; Asparagine; Aspartic Acid; Carbon Isotopes; Culture Media; Cysteine; Glucose; Glutamine; Glycine; Methionine; Oxygen Consumption; Proline; Salmonella; Serine; Threonine; Water | 1966 |
Modes of insulin resynthesis in liver.
Topics: Animals; Carbon Isotopes; Chromatography; Glycine; Insulin; Liver; Male; Oxidoreductases; Pancreas; Rats; Serine | 1966 |
The interconversion of glycine and serine by plant tissue extracts.
Topics: Carbon Isotopes; Chromatography, Paper; Folic Acid; Formaldehyde; Glycine; In Vitro Techniques; Plant Extracts; Plants; Serine | 1966 |
Amino acid incorporation by microsomal fractions from the liver of the domestic fowl.
Topics: Amino Acids; Animals; Glycine; In Vitro Techniques; Liver; Microscopy, Electron; Microsomes; Poultry; Protein Biosynthesis; Ranula; Serine; Trypsin | 1966 |
Gas chromatographic separation of DNP amino acids and its application to the analysis of serum amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Cholesterol; Chromatography, Gas; Glutamates; Glycine; Hydroxyproline; Indicators and Reagents; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Valine | 1966 |
Nuclear histones and early embryogenesis of the chick.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Cell Division; Cell Nucleus; Chick Embryo; Electrophoresis; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
Comparison of transfer RNA and aminoacyl RNA ligases from calf liver and spleen.
Topics: Animals; Cattle; Glycine; Histidine; In Vitro Techniques; Ligases; Liver; Lysine; Phenylalanine; RNA, Transfer; Serine; Spleen; Valine | 1966 |
Analysis of N-methylamino acids by automatic amino acid analyzer and gas-liquid chromatography.
Topics: Alanine; Anti-Bacterial Agents; Arginine; Aspartic Acid; Autoanalysis; Chromatography, Gas; Cysteine; Cystine; Glutamates; Glycine; Indicators and Reagents; Isoleucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1966 |
Incorporation of 14C from glucose into alpha-keto acids and amino acids in rat brain and liver in vivo.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Glucose; Glutamates; Glutamine; Glutarates; Glycine; Keto Acids; Liver; Male; Pyruvates; Rats; Serine | 1966 |
Studies on the growth of Prymnesium parvum Carter (chrysomonadina) and on the formation of its toxin (prymnesin).
Topics: Alanine; Eukaryota; Glycerol; Glycine; Light; Serine; Toxins, Biological | 1966 |
[Composition of the amino acid pool of Neurospora in deficiency of growth substance].
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Biotin; Choline; Chromatography, Ion Exchange; Culture Media; Glutamates; Glycine; Growth Inhibitors; Lysine; Methionine; Mutation; Neurospora; Phenylalanine; Pyridoxine; Riboflavin; Serine; Threonine; Tyrosine; Valine | 1966 |
[In vitro metabolism of adipose tissue. II. Metabolism of L-lysine, L-threonine, L-serine and glycine in epididymal adipose tissue of the normal rat].
Topics: Adipose Tissue; Animals; Autoanalysis; Biological Transport, Active; Carbon Dioxide; Culture Techniques; Epididymis; Glucose; Glycine; Insulin; Lipid Metabolism; Lysine; Male; Proteins; Rats; Serine; Stimulation, Chemical; Threonine | 1966 |
[Incorporation of C14- and H3-tryptophan into different serum proteins through the perfused isolated normal and irradiated liver].
Topics: Alanine; Albumins; Amino Acids; Animals; Blood Proteins; Carbon Isotopes; Chromatography; Electrophoresis; Globulins; Glycine; Liver; Perfusion; Phenylalanine; Radiation Effects; Rats; Serine; Tritium; Tryptophan | 1966 |
[Chromatographic investigation of free amino acids of the heart, kidneys and brain in experimental myocarditis].
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Brain; Chromatography, Paper; Cystine; Glutamine; Glycine; Histidine; Kidney; Lysine; Methionine; Myocarditis; Myocardium; Phenylalanine; Rabbits; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
The occurrence of hypotaurine and other sulfur-containing amino acids in seminal plasma and spermatozoa of boar, bull and dog.
Topics: Alanine; Amino Acids; Animals; Asparagine; Cattle; Dogs; Electrophoresis; Glutamates; Glycine; In Vitro Techniques; Leucine; Male; Semen; Serine; Spermatozoa; Swine; Taurine; Valine | 1966 |
Free amino acids of human foetal and adult liver.
Topics: Adult; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Cystine; Female; Fetus; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1966 |
[Study of amino acid compositiion of basic polypeptides of animal origin by paper chromatography method].
Topics: Alanine; Amino Acids; Animals; Arginine; Brain Chemistry; Cattle; Chromatography, Paper; Cystine; Glutamates; Glycine; Histidine; Humans; Kidney; Liver; Lysine; Peptides; Phenylalanine; Placenta; Serine; Tryptophan; Valine | 1966 |
The effect of a nutritional pyridoxine deficiency on free amino acids and related substances in mouse brain.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Brain Chemistry; Chromatography, Ion Exchange; Diet; Glycine; In Vitro Techniques; Methionine; Mice; Serine; Urea; Vitamin B 6 Deficiency | 1967 |
Pyruvate metabolism in thiamine-deficient calves.
Topics: Alanine; Animals; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Cattle; Coenzyme A; Glutamates; Glycine; Lactates; Liver; Pyruvates; Serine; Thiamine Deficiency | 1967 |
Renal metabolism of alanine.
Topics: Alanine; Ammonia; Animals; Dogs; Glomerular Filtration Rate; Glutamates; Glutamine; Glycine; Ketoglutaric Acids; Kidney; Kidney Tubules; Oxidation-Reduction; Pyruvates; Serine; Threonine | 1967 |
The recognition and isolation from urine and serum of a peptide inhibitor to calcification.
Topics: Animals; Aspartic Acid; Calcification, Physiologic; Calcium; Cartilage; Chromatography; Crystallization; Electrophoresis; Female; Glutamates; Glycine; Hydroxyapatites; Peptides; Phosphates; Rats; Rickets; Serine | 1967 |
Metabolic functions of myo-inositol. V. Utilization of glycine and serine in nucleotide and nucleic acid biosynthesis by inositol-deficient KB cells.
Topics: Carbon Isotopes; Culture Techniques; Glycine; Humans; Inositol; Mouth Neoplasms; Neoplasms; Nucleic Acids; Nucleotides; Serine; Transferases | 1967 |
Metabolic functions of myo-inositol. VI. Impairment of amino acid transport in KB cells caused by inositol deficiency.
Topics: Aminoisobutyric Acids; Carbon Isotopes; Culture Techniques; Glycine; Humans; Inositol; Kinetics; Mouth Neoplasms; Neoplasms; Serine | 1967 |
Further studies of amino acid transport by embryonic chick bone.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Bone and Bones; Chick Embryo; Dactinomycin; Ethylmaleimide; Glycine; In Vitro Techniques; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Serine transhydroxymethylase. Affinity of tetrahydrofolate compounds for the enzyme and enzyme-glycine complex.
Topics: Chemical Phenomena; Chemistry; Folic Acid; Glycine; Kinetics; Serine; Spectrophotometry; Transferases | 1967 |
Amino-acid transport by various leucocyte preparations: a comparative survey.
Topics: Amino Acids; Animals; Aspartic Acid; Biological Transport, Active; Cyanides; Dinitrophenols; Fluorides; Glycine; Guinea Pigs; In Vitro Techniques; Iodoacetates; Leucine; Leukocytes; Lymph Nodes; Lysine; Methionine; Proline; Serine; Spleen | 1967 |
Uptake and utilization of amino acids by resting cells of Nitrosomonas europaea.
Topics: Amino Acids; Aspartic Acid; Carbon Isotopes; Glycine; Nitrosomonas; Quaternary Ammonium Compounds; Serine; Valine | 1967 |
Effects of cortisol and 19-nortestosterone on the free amino acid pools and amino acid uptake of cultured cells.
Topics: Alanine; Amino Acids; Aspartic Acid; Biological Transport; Carbon Isotopes; Culture Techniques; Glycine; HeLa Cells; Hydrocortisone; Nandrolone; Neoplasms, Experimental; Serine; Threonine | 1967 |
Reactions in frozen systems. VI. Ice as a possible model for biological structured-water systems.
Topics: Acetylcholine; Asparagine; Catalysis; Chemical Phenomena; Chemistry; Copper; Cytosine; Dioxins; Glutamates; Glutamine; Glycine; Hydroxylamines; Ice; Imidazoles; Kinetics; Models, Theoretical; Nitrates; Phenylalanine; Piperazines; Potassium Chloride; Pyrazoles; Serine; Tyrosine | 1967 |
The recovery of amino acids from acid hydrolysates of whole urine from patients with thermal burns.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Burns; Creatine; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1967 |
Sequence peptide polymers. II. Poly Glu(OH)-Gly, poly Glu(OH)-Ser(H)-Gly, and their benzyl esters.
Topics: Amino Acid Sequence; Benzoates; Chemistry, Organic; Esters; Glycine; Organic Chemistry Phenomena; Peptides; Polymers; Serine | 1967 |
Urinary amino acids of rats receiving high sugar diets.
Topics: Alanine; Alcohols; Amino Acids; Animals; Arabinose; Ascorbic Acid; Asparagine; Aspartic Acid; Dietary Carbohydrates; Female; Galactose; Glucose; Glutamates; Glycine; Inositol; Intestines; Neomycin; Rats; Ribose; Serine; Taurine; Threonine; Xylitol; Xylose | 1967 |
Electron microscopic and biochemical characterization of collagen in blattarian insects.
Topics: Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Collagen; Connective Tissue Cells; Cysteine; Cystine; Female; Glutamates; Glycine; Histidine; Histocytochemistry; Hydroxyproline; Insecta; Isoleucine; Leucine; Lysine; Male; Methionine; Microscopy, Electron; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1967 |
Sequence peptide polymers. 3. Poly Asp(OH)-Ser(H)-Gly and other serine-containing polymers.
Topics: Amino Acid Sequence; Aspartic Acid; Chemical Phenomena; Chemistry; Chemistry, Organic; Glycine; Models, Theoretical; Organic Chemistry Phenomena; Peptides; Serine | 1967 |
Rapid short-column chromatography of amino acids. A method for blood and urine specimens in the diagnosis and treatment of metabolic disease.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Aminobutyrates; Autoanalysis; Buffers; Chromatography, Ion Exchange; Citrates; Cysteine; Cystine; Glutamates; Glutamine; Glycine; Humans; Hydrogen-Ion Concentration; Hydroxyproline; Isoleucine; Phenylalanine; Proline; Sarcosine; Serine; Threonine; Tyrosine; Valine | 1967 |
Gluconeogenesis from amino acids in neonatal rat liver.
Topics: Alanine; Alanine Transaminase; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartate Aminotransferases; Aspartic Acid; Gluconeogenesis; Glutamates; Glycine; Histidine; In Vitro Techniques; Leucine; Liver; Liver Glycogen; Phenylalanine; Proline; Rats; Serine; Spectrophotometry; Threonine; Tyrosine; Valine | 1967 |
Glycine synthesis by extracts of acetone powder of rat-liver mitochondria.
Topics: Acetone; Animals; Carbon Isotopes; Dialysis; Folic Acid; Glycine; Liver; Mitochondria; Pyridoxal Phosphate; Rats; Serine; Transferases | 1967 |
Effect of dietary protein levels, amino acid supplementation and nitrogen source upon the plasma free amino acid concentrations in growing lambs.
Topics: Amino Acids; Animals; Diet; Dietary Proteins; Glycine; Histidine; Lysine; Methionine; Nitrogen; Rumen; Serine; Sheep; Urea | 1967 |
Alleviation of methionine and homocystine toxicity in the rat.
Topics: Amino Acids; Animals; Body Weight; Diet; Glycine; Growth; Homocystine; Male; Methionine; Rats; Serine | 1967 |
The influence of nitrogenous compounds on growth of Pythium species.
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Cysteine; Fungi; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Nitrates; Nitrites; Nitrogen; Peptones; Quaternary Ammonium Compounds; Serine; Succinates; Threonine; Yeast, Dried | 1967 |
Metabolism of serine and glycine in baker's yeast.
Topics: Acetaldehyde; Acetates; Adenine; Carbon Isotopes; Citric Acid Cycle; Formates; Glucose; Glycine; Glycolates; Glyoxylates; Guanine; Histidine; Kinetics; Oxidation-Reduction; Pyruvates; Saccharomyces; Serine; Stimulation, Chemical | 1967 |
Effect of amino acids on zinc-65 incorporation by Ehrlich ascites tumor cells in vitro.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carcinoma, Ehrlich Tumor; Female; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Lysine; Methionine; Mice; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Zinc; Zinc Isotopes | 1967 |
Schizophrenia-like psychosis caused by a metabolic disorder.
Topics: Adolescent; Adult; Antipsychotic Agents; Diagnosis, Differential; Female; Glycine; Humans; Porphyrias; Psychoses, Substance-Induced; Psychotic Disorders; Schizophrenia; Serine; Skin Diseases | 1980 |
Influence of phenothiazines or reserpine on the formation of 14C-glycine from U-14C-serine.
Topics: Animals; Brain; Chlorpromazine; Dose-Response Relationship, Drug; Glycine; Glycine Hydroxymethyltransferase; Male; Phenothiazines; Rats; Reserpine; Serine; Subcellular Fractions | 1981 |
Effects of some putative amino acid neurotransmitters on the stimulated TSH secretion in male rats.
Topics: Amino Acids; Animals; Cold Temperature; Glutamates; Glutamic Acid; Glycine; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Thyrotropin; Time Factors | 1983 |
Effects of a nonspecific nitrogen deficiency on growth rate and leg problems in chicks.
Topics: Amino Acids, Essential; Animals; Body Weight; Bone Diseases, Metabolic; Chickens; Glutamates; Glutamic Acid; Glycine; Male; Nitrogen; Nutritional Requirements; Poultry Diseases; Serine; Stereoisomerism | 1984 |
Study of the relationship between free amino acids and cataract in human lenses.
Topics: Adult; Aged; Alanine; Amino Acids; Cataract; Glutamates; Glutamic Acid; Glycine; Humans; Lens, Crystalline; Leucine; Middle Aged; Serine; Threonine | 1984 |
Serine metabolism and psychosis.
Topics: Adult; Antipsychotic Agents; Brief Psychiatric Rating Scale; Diet; Glycine; Glycine Hydroxymethyltransferase; Humans; Mental Disorders; Middle Aged; Psychotic Disorders; Serine; Transferases | 1984 |
Symmetrical distribution of amino acid neurotransmitters in the right and left cerebral cortex of the rat.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Glycine; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Threonine; Tissue Distribution | 1984 |
Regulation of net amino acid exchange in sea urchin larvae.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Glycine; Larva; Sea Urchins; Serine; Time Factors | 1984 |
Variability in the phenotypic expression of abnormal sarcosine metabolism in a family.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Child, Preschool; Female; Genetic Variation; Glycine; Humans; Intellectual Disability; Male; Phenotype; Sarcosine; Serine | 1983 |
The tsx protein of Escherichia coli can act as a pore for amino acids.
Topics: Amino Acids; Arginine; Bacterial Proteins; Biological Transport; Escherichia coli; Glucose; Glycine; Membrane Proteins; Phenylalanine; Porins; Serine | 1981 |
The role of folate deficiency in electrophysiological neuropathy of experimental hepatoma of the rats.
Topics: Animals; Folic Acid Deficiency; Glycine; Liver Neoplasms, Experimental; Male; Neural Conduction; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains; Serine | 1981 |
Control of hepatic utilization of serine, glycine and threonine in fed and starved rats.
Topics: Alanine; Alanine Transaminase; Animals; Dietary Carbohydrates; Dietary Proteins; Gluconeogenesis; Glycine; L-Serine Dehydratase; Lactates; Lactic Acid; Liver; Male; Rats; Serine; Starvation; Threonine | 1983 |
Biosynthesis of purines by a proplastid fraction from soybean nodules.
Topics: Glycine; Glycine max; Purines; Serine | 1983 |
Glycine/serine ratios in amniotic fluid: an unreliable indicator for the prenatal diagnosis of nonketotic hyperglycinemia.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Amniotic Fluid; Female; Glycine; Humans; Pregnancy; Prenatal Diagnosis; Serine | 1983 |
Glycine and serine rich peptides isolated from rat liver preparations enriched with smooth endoplasmic membranes.
Topics: Animals; Endoplasmic Reticulum; Glycine; Intracellular Membranes; Liver; Male; Peptides; Rats; Rats, Inbred Strains; Serine | 1983 |
Serine and glycine-induced catalepsy in porphyric rats: an animal model for psychosis?
Topics: Allylisopropylacetamide; Aminolevulinic Acid; Animals; Catalepsy; Disease Models, Animal; Glycine; Humans; Male; Phenobarbital; Porphobilinogen; Porphyrias; Psychotic Disorders; Rats; Rats, Inbred Strains; Serine | 1983 |
Transport of glycine, serine, and proline into spinach leaf mitochondria.
Topics: Biological Transport, Active; Glycine; Kinetics; Mitochondria; Oxygen Consumption; Plants; Proline; Serine | 1983 |
Amino acid precursors of Myxococcus xanthus antibiotic TA.
Topics: Acetates; Alanine; Amino Acids; Anti-Bacterial Agents; Carbon Radioisotopes; Glycine; Macrolides; Myxococcales; Serine | 1983 |
Purification and sequence analysis of bioactive atrial peptides (atriopeptins).
Topics: Amino Acid Sequence; Animals; Arginine; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Diuresis; Glycine; Heart Atria; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Natriuresis; Peptides; Phenylalanine; Rats; Serine | 1984 |
Purine biosynthesis de novo in rat skeletal muscle.
Topics: Adenine; Adenosine; Animals; Azaserine; Cycloserine; Female; Formates; Glycine; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Male; Muscles; Purines; Rats; Rats, Inbred Strains; Serine | 1983 |
Problems of prenatal diagnosis of non-ketotic hyperglycinaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Amniocentesis; Amniotic Fluid; Female; Fetal Diseases; Glycine; Humans; Pregnancy; Prenatal Diagnosis; Serine | 1983 |
How signal sequences maintain cleavage specificity.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Endopeptidases; Eukaryotic Cells; Glycine; Membrane Proteins; Peptides; Prokaryotic Cells; Protein Sorting Signals; Serine; Serine Endopeptidases | 1984 |
Independent plasma levels of sodium and glycine during transurethral resection of the prostate.
Topics: Aged; Alanine; Animals; Blood Glucose; Dogs; Glycine; Humans; Hyponatremia; Intraoperative Complications; Male; Osmolar Concentration; Prostatectomy; Serine | 1984 |
A silent hemoglobin variant detected by HPLC: hemoglobin City of Hope beta 69 (E13) Gly----Ser.
Topics: Adult; Amino Acid Sequence; Amino Acids; Chromatography, High Pressure Liquid; Glycine; Hemoglobins, Abnormal; Humans; Male; Serine | 1984 |
In vivo studies on the metabolic derangement in a patient with D-glyceric acidaemia and hyperglycinaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Carbohydrate Dehydrogenases; Child, Preschool; Diet; Fructose; Glyceric Acids; Glycine; Humans; Male; Proline; Propionates; Riboflavin; Serine | 1984 |
The amino terminal acetylation of cat globin chains and their tryptic peptides.
Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Animals; Cats; Chromatography, High Pressure Liquid; Globins; Glycine; Hemoglobin A; Hemoglobins; Peptide Fragments; Protein Processing, Post-Translational; Ribosomes; Serine; Trypsin | 1984 |
Impaired glycine-serine conversion and increased plasma taurine levels in episodic psychotic patients with psychedelic symptoms.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Acute Disease; Adult; Female; Glycine; Hallucinations; Humans; Male; Serine; Taurine | 1984 |
General approach to bacterial nutrition: growth factor requirements of Moraxella nonliquefaciens.
Topics: Amino Acids; Culture Media; Glycine; Hypoxanthine; Hypoxanthines; Kinetics; Lactates; Lactic Acid; Methionine; Moraxella; Nitrogen; Serine; Species Specificity; Vitamins | 1984 |
Factors affecting the biosynthesis of L-tryptophan by genetically modified strains of Escherichia coli.
Topics: Escherichia coli; Formates; Glycine; Glycine Hydroxymethyltransferase; Indoles; Serine; Tryptophan; Tryptophan Synthase | 1984 |
Elevation of gamma-aminobutyric acid in cultured rat C6 glioma cells following methionine supplementation.
Topics: Amino Acids; Animals; Cell Line; gamma-Aminobutyric Acid; Glioma; Glycine; Methionine; Rats; Serine | 1980 |
Serine utilization in the chick as influenced by dietary pyridoxine.
Topics: Animals; Aspartate Aminotransferases; Chickens; Glycine; Growth; In Vitro Techniques; Pyridoxine; Serine; Vitamin B 6 Deficiency | 1980 |
A Ser162/Gly162 polymorphism in Japanese quail ovomucoid.
Topics: Amino Acids; Animals; Birds; Coturnix; Egg Proteins; Female; Glycine; Ovomucin; Peptide Fragments; Polymorphism, Genetic; Serine; Species Specificity; Trypsin | 1980 |
[Osteogenesis imperfecta with ketone hyperglycinemia, hyperserinemia and hyperornithinemia].
Topics: Child; Female; Glycine; Humans; Ornithine; Osteogenesis Imperfecta; Serine | 1980 |
Plasma amino acids in 3/sec spike-wave epilepsy.
Topics: Adolescent; Adult; Alanine; Amino Acids; Aspartic Acid; Child; Child, Preschool; Epilepsy; Female; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Male; Methionine; Middle Aged; Phenylalanine; Serine; Taurine; Threonine; Tyrosine; Valine | 1980 |
Nitrogen economy and the metabolism of serine and glycine in reticulocytes of rabbits.
Topics: Amino Acids; Animals; Carbon; Cytosol; Glucose; Glycine; Hemoglobins; Mitochondria; Nitrogen; Rabbits; Reticulocytes; Serine | 1980 |
Studies of glycine metabolism and transport in fibroblasts from patients with nonketotic hyperglycinemia.
Topics: Biological Transport; Fibroblasts; Glycine; Humans; Kinetics; Serine; Valine | 1980 |
Effect of methionine, glycine and serine on serine hydroxymethyltransferase activity in rat glioma and human neuroblastoma cells.
Topics: Animals; Brain Neoplasms; Cell Line; Enzyme Activation; Glioma; Glycine; Glycine Hydroxymethyltransferase; Humans; Methionine; Neoplasms, Experimental; Neuroblastoma; Rats; Serine; Transferases | 1980 |
[On the problems in respect ot the formation of N-nitroso compound precursors when using alkylating agents in the fumigation of foodstuffs. I. Investigations of the formation of secondary amines by the action of ethylene oxide on primary amines and amino
Topics: Amines; Amino Acids; Decarboxylation; Ethanolamines; Ethylamines; Ethylene Oxide; Food Preservation; Fumigation; Glycine; Methylamines; Nitrosamines; Serine | 1980 |
The metabolism of serine and glycine in mutant lines of Chinese hamster ovary cells.
Topics: Amino Acids; Animals; Cell Line; Cricetinae; Cricetulus; Cytosol; Female; Glycine; Glycine Hydroxymethyltransferase; Mitochondria; Mutation; Ovary; Oxidation-Reduction; Protein Biosynthesis; Serine | 1980 |
Role of the glycine-cleavage system in glycine and serine metabolism in various organs.
Topics: Amino Acid Oxidoreductases; Aminomethyltransferase; Animals; Carrier Proteins; Glycine; Glycine Dehydrogenase (Decarboxylating); Hydroxymethyl and Formyl Transferases; L-Serine Dehydratase; Molecular Weight; Multienzyme Complexes; Organ Specificity; Rats; Serine; Species Specificity; Transferases | 1980 |
Progressive neurodegenerative disorder in a patient with nonketotic hyperglycinemia.
Topics: Amino Acid Metabolism, Inborn Errors; Central Nervous System Diseases; Cerebral Cortex; Female; Glycine; Humans; Infant; Infant, Newborn; Nerve Degeneration; Serine; Valine | 1981 |
Effects of central administration of alanine on body temperature of the rabbit: comparisons with the effects of serine, glycine and taurine.
Topics: Alanine; Animals; Bacterial Toxins; Body Temperature Regulation; Endotoxins; Enterotoxins; Glycine; Injections, Intraventricular; Interleukin-1; Male; Prostaglandins E; Proteins; Rabbits; Serine; Taurine | 1981 |
13C nuclear magnetic resonance suggests a flexible proteoglycan core protein.
Topics: Animals; Carbon Isotopes; Chick Embryo; Glycine; Glycosaminoglycans; Macromolecular Substances; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Conformation; Proteoglycans; Serine | 1981 |
Amino acid transport via the red cell anion transport system.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Alanine; Amino Acids; Biological Transport; Carrier Proteins; Cysteine; Depression, Chemical; Erythrocytes; Glycine; Humans; In Vitro Techniques; Proline; Serine; Threonine; Valine | 1981 |
Glycine nitrogen metabolism in man.
Topics: Adult; Amino Acids; Glycine; Humans; Kinetics; Male; Nitrogen; Nitrogen Isotopes; Proteins; Serine; Urea | 1981 |
Mutation modifying the serine pathway in methylotrophic bacteria.
Topics: Bacillus; Carbohydrate Dehydrogenases; Glyceric Acids; Glycine; Glycine Hydroxymethyltransferase; Isocitrate Lyase; Methanol; Micrococcus; Mutation; Serine; Transaminases | 1981 |
Effect of non-essential amino acids on fetal rat pancreatic growth and insulin secretion in vitro.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Glycine; Insulin; Insulin Secretion; Organ Culture Techniques; Pancreas; Proline; Rats; Rats, Inbred Strains; Serine | 1981 |
Prenatal diagnosis of nonketotic hyperglycinemia.
Topics: Amino Acid Metabolism, Inborn Errors; Amniotic Fluid; Female; Glycine; Heterozygote; Homozygote; Humans; Infant, Newborn; Male; Pregnancy; Prenatal Diagnosis; Serine | 1982 |
Sources of one-carbon units in the folate pathway of Escherichia coli.
Topics: Amino Acids; Carbon Radioisotopes; Escherichia coli; Folic Acid; Formates; Glycine; Serine | 1982 |
Amino acids derivatives synthesis from nitrogen, carbon and water by electric discharges.
Topics: Amino Acids; Carbon; Chromatography, Gas; Diketopiperazines; Electricity; Glycine; Hydrolysis; Nitrogen; Piperazines; Pressure; Serine; Urea; Water | 1981 |
Purine metabolism in Trypanosoma brucei gambiense.
Topics: Formates; Glucose; Glycine; Guanine Deaminase; Purine Nucleosides; Purine Nucleotides; Purines; Serine; Trypanosoma brucei brucei | 1982 |
Metabolism of serine, glycine and threonine in isolated cat hepatocytes Felis domestica.
Topics: Animals; Biotransformation; Cats; Glucose; Glycine; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Oxidation-Reduction; Serine; Threonine | 1982 |
Prenatal diagnosis of glycine encephalopathy.
Topics: Amino Acid Metabolism, Inborn Errors; Amniotic Fluid; Brain Diseases, Metabolic; Female; Glycine; Humans; Infant; Infant, Newborn; Male; Pregnancy; Prenatal Diagnosis; Serine | 1982 |
L-serine degradation in Escherichia coli K-12: a combination of L-serine, glycine, and leucine used as a source of carbon.
Topics: Energy Metabolism; Escherichia coli; Glucose; Glycine; Leucine; Oxygen Consumption; Serine; Triose-Phosphate Isomerase | 1982 |
A strategy for glycine encephalopathy therapy.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acid Oxidoreductases; Aminomethyltransferase; Animals; Brain Diseases, Metabolic; Carrier Proteins; Chemical Phenomena; Chemistry; Glycine; Glycine Dehydrogenase (Decarboxylating); Humans; Hydroxymethyl and Formyl Transferases; Infant; Infant, Newborn; Methionine; Mice; Serine; Tetrahydrofolates; Transferases | 1982 |
[Amino acid imbalances in blood of pregnant women with diabetes and in blood of their newborns--limit values for screening (author's transl)].
Topics: Amino Acids; Female; Glutamates; Glycine; Humans; Infant, Newborn; Methionine; Pregnancy; Pregnancy in Diabetics; Serine; Threonine; Valine | 1982 |
Glycine metabolism in rat kidney cortex slices.
Topics: Amino Acids; Ammonia; Animals; Benzoates; Benzoic Acid; Carbon Dioxide; Glycine; In Vitro Techniques; Kidney Cortex; Male; Rats; Rats, Inbred Strains; Serine; Tissue Distribution; Urea | 1982 |
Purine metabolism in the bloodstream forms of Trypanosoma gambiense and Trypanosoma rhodesiense.
Topics: Animals; Carbon Radioisotopes; Formates; Glucose; Glycine; Kinetics; Purine Nucleotides; Purines; Serine; Species Specificity; Trypanosoma; Trypanosoma brucei gambiense | 1982 |
Regulation of phosphoglycerate dehydrogenase levels and effect on serine synthesis in Escherichia coli K-12.
Topics: Amino Acids; Carbohydrate Dehydrogenases; Escherichia coli; Genes; Glyceric Acids; Glycine; Kinetics; Lactates; Phosphoglycerate Dehydrogenase; Serine | 1980 |
Antagonistic effects of isovalerate and glycine on plasma choline levels in rabbits.
Topics: Animals; Choline; Glycine; Male; Rabbits; Serine; Valerates | 1980 |
Decreased cysteine and proline synthesis in parenterally fed, premature infants.
Topics: Alanine; Amino Acids; Aspartic Acid; Birth Weight; Blood Glucose; Carbon Isotopes; Cysteine; Electrolytes; Energy Intake; Female; Food, Formulated; Gas Chromatography-Mass Spectrometry; Gestational Age; Glucose; Glutamic Acid; Glycine; Humans; Infant Food; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Lipids; Male; Parenteral Nutrition; Parenteral Nutrition Solutions; Proline; Serine; Solutions | 1995 |
Genetics of the synthesis of serine from glycine and the utilization of glycine as sole nitrogen source by Saccharomyces cerevisiae.
Topics: Amino Acid Oxidoreductases; Cloning, Molecular; Dihydrolipoamide Dehydrogenase; Fungal Proteins; Genes, Fungal; Genetic Complementation Test; Glycine; Glycine Dehydrogenase (Decarboxylating); Multienzyme Complexes; Nitrogen; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine | 1995 |
Molecular basis of cystathionine beta-synthase deficiency in pyridoxine responsive and nonresponsive homocystinuria.
Topics: Adult; Amino Acid Sequence; Base Sequence; Cystathionine beta-Synthase; DNA; Exons; Female; Genes, Recessive; Glycine; Homocystinuria; Humans; Introns; Male; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Pyridoxine; RNA; Serine | 1993 |
Excitatory amino acid neurotransmission through both NMDA and non-NMDA receptors is involved in the anticonvulsant activity of felbamate in DBA/2 mice.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Binding, Competitive; Disease Models, Animal; Dose-Response Relationship, Drug; Felbamate; Female; Glycine; Injections, Intraperitoneal; Injections, Intraventricular; Kynurenic Acid; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Phenylcarbamates; Propylene Glycols; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Serine; Stereoisomerism; Synaptic Transmission | 1994 |
A molecular sensor system based on genetically engineered alkaline phosphatase.
Topics: Alkaline Phosphatase; Amino Acid Sequence; Antibodies; Aspartic Acid; Binding Sites, Antibody; Binding, Competitive; Capsid; Epitopes; Escherichia coli; Genes, Bacterial; Genetic Engineering; Glycine; Hepacivirus; HIV Envelope Protein gp120; HIV-1; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Point Mutation; Protein Conformation; Recombinant Proteins; Serine; Viral Core Proteins | 1995 |
Mutations in the elongation factor 2 gene which confer resistance to diphtheria toxin and Pseudomonas exotoxin A. Genetic and biochemical analyses.
Topics: ADP Ribose Transferases; Amino Acid Sequence; Animals; Asparagine; Bacterial Toxins; Base Sequence; CHO Cells; Cricetinae; Diphtheria Toxin; Drug Resistance; Exotoxins; Glycine; Histidine; Humans; Isoleucine; Molecular Sequence Data; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphoproteins; Plasmids; Point Mutation; Polymorphism, Restriction Fragment Length; Protein Synthesis Inhibitors; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Recombinant Proteins; Restriction Mapping; Sequence Homology, Amino Acid; Serine; Transfection; Virulence Factors | 1995 |
Substitution at residue 473 confers progesterone 21-hydroxylase activity to cytochrome P450 2C2.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Enzyme Stability; Glycine; Kidney; Mixed Function Oxygenases; Molecular Sequence Data; Mutation; Proline; Sequence Homology, Amino Acid; Serine; Steroid 21-Hydroxylase; Structure-Activity Relationship; Valine | 1995 |
A mutation in the glucagon receptor gene (Gly40Ser): heterogeneity in the association with diabetes mellitus.
Topics: Adolescent; Adult; Age of Onset; Aged; Diabetes Mellitus, Type 2; France; Genetic Linkage; Glycine; Humans; Italy; Japan; Middle Aged; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Random Allocation; Receptors, Glucagon; Serine | 1995 |
Anxiogenic-like effect of glycine and D-serine microinjected into dorsal periaqueductal gray matter of rats.
Topics: Animals; Anxiety; Dose-Response Relationship, Drug; Glycine; Male; Maze Learning; Microinjections; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism | 1995 |
The unique extracellular disulfide loop of the glycine receptor is a principal ligand binding element.
Topics: Amino Acid Sequence; Binding Sites; Cells, Cultured; Cysteine; Disulfides; Extracellular Matrix; Glycine; Humans; Kinetics; Ligands; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Receptors, Glycine; Serine; Strychnine; Taurine; Threonine; Tyrosine | 1995 |
Alteration of [3H]MK-801 binding associated with the N-methyl-D-Aspartate receptor complex by acute ethanol in rat cortex and hippocampus in vitro.
Topics: Animals; Cerebral Cortex; Culture Techniques; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ethanol; Glutamic Acid; Glycine; Hippocampus; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Serine; Synaptic Membranes; Synaptic Transmission | 1995 |
The oxidation of amino acids by ferrate(V). A pre-mix pulse radiolysis study.
Topics: Amino Acids; Glycine; Hydrogen-Ion Concentration; Iron; Methionine; Oxidation-Reduction; Phenylalanine; Pulse Radiolysis; Serine | 1995 |
Isolation and partial characterization of rat sperm tail fibrous sheath proteins and comparison with rabbit and human spermatozoa using a polyclonal antiserum.
Topics: Animals; Aspartic Acid; Blotting, Western; Cystine; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Glutamic Acid; Glycine; Humans; Immune Sera; Leucine; Male; Microscopy, Electron; Proteins; Rabbits; Rats; Rats, Sprague-Dawley; Serine; Sperm Tail | 1995 |
Extracellular concentration of endogenous free D-serine in the rat brain as revealed by in vivo microdialysis.
Topics: Amino Acids; Animals; Brain; Cerebellum; Corpus Striatum; Extracellular Space; Glutamic Acid; Glycine; Kinetics; Male; Microdialysis; Organ Specificity; Prefrontal Cortex; Rats; Rats, Wistar; Serine; Sodium Channel Blockers; Stereoisomerism; Tetrodotoxin; Veratrine | 1995 |
Determination of multiply labeled serine and glycine isotopomers in human plasma by isotope dilution negative-ion chemical ionization mass spectrometry.
Topics: Gas Chromatography-Mass Spectrometry; Glycine; Humans; Indicators and Reagents; Male; Radioisotope Dilution Technique; Serine | 1995 |
Isolation and characterization of the human muscle glycogen synthase gene.
Topics: Adult; Amino Acid Sequence; Animals; Base Sequence; Deoxyribonucleases, Type II Site-Specific; Diabetes Mellitus, Type 2; DNA; DNA Primers; Exons; Female; Finland; Glycine; Glycogen Synthase; Hominidae; Humans; Insulin Resistance; Introns; Middle Aged; Molecular Sequence Data; Muscle, Skeletal; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Reference Values; Restriction Mapping; Sequence Homology, Nucleic Acid; Serine; Transcription, Genetic | 1995 |
Mutation screening of dihydropyridine receptor gamma subunit cDNA from malignant hyperthermia susceptible patients.
Topics: Amino Acid Sequence; Base Sequence; Calcium Channels; Calcium Channels, L-Type; Chromosome Mapping; Chromosomes, Human, Pair 17; Deoxyribonucleases, Type II Site-Specific; DNA Primers; Genetic Predisposition to Disease; Glycine; Humans; Macromolecular Substances; Malignant Hyperthermia; Molecular Sequence Data; Muscle, Skeletal; Point Mutation; Polymerase Chain Reaction; Restriction Mapping; Serine | 1995 |
Involvement of serine 96 in the catalytic mechanism of ferredoxin-NADP+ reductase: structure--function relationship as studied by site-directed mutagenesis and X-ray crystallography.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Crystallography, X-Ray; DNA Primers; Ferredoxin-NADP Reductase; Flavin-Adenine Dinucleotide; Glycine; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Point Mutation; Protein Conformation; Protein Folding; Recombinant Proteins; Serine; Spectrometry, Fluorescence; Spectrophotometry; Structure-Activity Relationship; Valine | 1995 |
Designed replacement of an internal hydration water molecule in BPTI: structural and functional implications of a glycine-to-serine mutation.
Topics: Amino Acid Sequence; Aprotinin; Fibrinolysin; Glycine; Humans; Hydrogen Bonding; Kallikreins; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Protein Denaturation; Serine; Structure-Activity Relationship; Thermodynamics; Trypsin; Water | 1993 |
Pregnenolone sulfate potentiation of N-methyl-D-aspartate receptor channels in hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Electrophysiology; Glycine; Hippocampus; Ibotenic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Neurons; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine | 1993 |
Felbamate modulates the strychnine-insensitive glycine receptor.
Topics: Animals; Anticonvulsants; Calcium; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Felbamate; Glycine; Mice; N-Methylaspartate; Phenylcarbamates; Propylene Glycols; Receptors, Glycine; Serine; Strychnine | 1995 |
Protein engineering of the relative specificity of glucoamylase from Aspergillus awamori based on sequence similarities between starch-degrading enzymes.
Topics: Amino Acid Sequence; Aspergillus; Base Sequence; Glucan 1,4-alpha-Glucosidase; Glycine; Hydrogen-Ion Concentration; Kinetics; Maltose; Molecular Sequence Data; Mutagenesis, Site-Directed; Sequence Alignment; Serine; Substrate Specificity | 1994 |
GLY113-->ASP can restore activity to the ASP51-->SER mutant in the melibiose carrier of Escherichia coli.
Topics: Amino Acid Sequence; Aspartic Acid; Escherichia coli; Glycine; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Serine; Symporters | 1995 |
2.8-A structure of yeast serine carboxypeptidase.
Topics: Amino Acid Sequence; Binding Sites; Carboxypeptidases; Cathepsin A; Computer Graphics; Crystallization; Crystallography, X-Ray; Disulfides; Glycine; Models, Molecular; Molecular Sequence Data; Protein Folding; Protein Structure, Secondary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Serine | 1994 |
Glycine enhances the central depressant properties of ethanol in mice.
Topics: Animals; Bicuculline; Central Nervous System Depressants; Drug Synergism; Ethanol; Glycine; Injections, Intraventricular; Male; Mice; Postural Balance; Serine; Strychnine | 1995 |
Substitution of aspartic acid for glycine at position 310 in type II collagen produces achondrogenesis II, and substitution of serine at position 805 produces hypochondrogenesis: analysis of genotype-phenotype relationships.
Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; Bone Diseases, Developmental; Cartilage; Cells, Cultured; Collagen; Collagen Diseases; Drug Stability; Electrophoresis; Exons; Female; Genotype; Glycine; Hot Temperature; Humans; Molecular Sequence Data; Mutation; Phenotype; Pregnancy; Protein Denaturation; Serine | 1995 |
Evidence for indirect utilization of glycine for production of N-bases of glycerophospholipids and sphingolipids in mouse neuroblastoma cells by using 15N-labeled glycine.
Topics: Animals; Cell Line; Choline; Ethanolamine; Ethanolamines; Glycine; Mice; Neuroblastoma; Phosphatidic Acids; Serine; Sphingolipids | 1995 |
The lysostaphin endopeptidase resistance gene (epr) specifies modification of peptidoglycan cross bridges in Staphylococcus simulans and Staphylococcus aureus.
Topics: Cell Wall; Cloning, Molecular; Drug Resistance, Microbial; Genes, Bacterial; Glycine; Lysostaphin; Peptidoglycan; Serine; Staphylococcus; Staphylococcus aureus | 1995 |
Two naturally occurring amino acid substitutions in the human 5-HT1A receptor: glycine 22 to serine 22 and isoleucine 28 to valine 28.
Topics: Alleles; Amino Acid Sequence; Amino Acids; Base Sequence; DNA Primers; Glycine; Humans; Isoleucine; Molecular Sequence Data; Mutation; Polymorphism, Single-Stranded Conformational; Receptors, Serotonin; Serine; Valine | 1995 |
Mutational analysis of the putative substrate-binding site of 3C proteinase of coxsackievirus B3.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Conserved Sequence; DNA Primers; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Enterovirus B, Human; Escherichia coli; Glycine; Histidine; Molecular Sequence Data; Mutation; Sequence Alignment; Serine; Threonine | 1995 |
Functional comparison of D-serine and glycine in rodents: the effect on cloned NMDA receptors and the extracellular concentration.
Topics: Animals; Cloning, Molecular; Electrophysiology; Extracellular Space; Glycine; Male; Microdialysis; Mutagenesis, Site-Directed; Oocytes; Osmolar Concentration; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine; Xenopus laevis | 1995 |
Evidence for glycine modulation of excitatory synaptic inputs to retinal ganglion cells.
Topics: Ambystoma; Animals; Biological Transport; Dendrites; Dose-Response Relationship, Drug; Evoked Potentials; Glycine; In Vitro Techniques; Kinetics; Kynurenic Acid; Light; Patch-Clamp Techniques; Potassium Chloride; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Serine; Stereoisomerism; Synapses; Synaptic Transmission; Time Factors | 1995 |
Differential expression and mutation of NME genes in autologous cultured human melanoma cells with different metastatic potentials.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Clone Cells; DNA Primers; Gene Expression; Genes, Tumor Suppressor; Glycine; Humans; Melanoma; Mice; Mice, Nude; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Neoplasm Metastasis; Neuroblastoma; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Phenotype; Phosphorylation; Point Mutation; Polymerase Chain Reaction; RNA, Messenger; Serine; Skin Neoplasms; Transcription Factors; Transcription, Genetic; Transplantation, Heterologous; Tumor Cells, Cultured | 1995 |
Time-related cortical amino acid changes after basal forebrain lesion: a microdialysis study.
Topics: Alzheimer Disease; Amino Acids; Animals; Brain Diseases; Cerebral Cortex; Chromatography, High Pressure Liquid; Fluorescence; Glutamic Acid; Glycine; Ibotenic Acid; Male; Microdialysis; Potassium; Rats; Rats, Sprague-Dawley; Serine; Taurine; Time Factors | 1995 |
Circadian variations of amino acid content of suprachiasmatic nucleus in rats.
Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Circadian Rhythm; Glycine; Light; Male; Rats; Rats, Wistar; Serine; Suprachiasmatic Nucleus | 1994 |
A Gly238Ser substitution in the alpha 2 chain of type I collagen results in osteogenesis imperfecta type III.
Topics: Base Sequence; Cells, Cultured; Child, Preschool; Collagen; Female; Glycine; Humans; Molecular Sequence Data; Osteogenesis Imperfecta; Phenotype; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Serine | 1995 |
The GS domain of the transforming growth factor-beta type I receptor is important in signal transduction.
Topics: Activin Receptors, Type I; Amino Acid Sequence; Animals; Cell Line; Chlorocebus aethiops; Cross-Linking Reagents; Glycine; Humans; Kidney; Lung; Mink; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Serine; Signal Transduction; Succinimides; Transcription, Genetic; Transfection; Transforming Growth Factor beta | 1995 |
Transthyretin Ser 6 gene frequency in individuals without amyloidosis.
Topics: Amyloidosis; Founder Effect; Gene Frequency; Glycine; Humans; Point Mutation; Polymorphism, Genetic; Prealbumin; Serine; White People | 1995 |
Paramagnetic molecular centers in gamma-irradiated aluminum hydroxide complexed with glycine or serine.
Topics: Aluminum Hydroxide; Electron Spin Resonance Spectroscopy; Gamma Rays; Glycine; Serine | 1995 |
Centrally-administered glycine antagonists increase locomotion in monoamine-depleted mice.
Topics: Animals; Behavior, Animal; Biogenic Monoamines; Glycine; Male; Mice; Motor Activity; Pyrrolidinones; Receptors, N-Methyl-D-Aspartate; Serine; Stimulation, Chemical | 1994 |
Drosophila GABA-gated chloride channel: modified [3H]EBOB binding site associated with Ala-->Ser or Gly mutants of Rdl subunit.
Topics: Alanine; Animals; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Drosophila melanogaster; Drosophila Proteins; gamma-Aminobutyric Acid; Glycine; Insecticide Resistance; Ion Channel Gating; Muscimol; Mutation; Receptors, GABA-A; Serine; Structure-Activity Relationship; Tritium | 1995 |
The Escherichia coli glycine transport system and its role in the regulation of the glycine cleavage enzyme system.
Topics: Amino Acid Oxidoreductases; Amino Acid Transport Systems, Neutral; Carbohydrate Dehydrogenases; Carrier Proteins; Cytochrome c Group; Escherichia coli; Gene Expression Regulation, Bacterial; Genotype; Glycine; Glycine Plasma Membrane Transport Proteins; Kinetics; Multienzyme Complexes; Phenotype; Phosphoglycerate Dehydrogenase; Serine; Transduction, Genetic; Transferases | 1995 |
Functional analysis of Gln-237 mutants of HhaI methyltransferase.
Topics: Base Sequence; Cytosine; DNA-Cytosine Methylases; DNA, Bacterial; Glycine; Guanosine; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Protein Binding; Protein Conformation; Serine; Substrate Specificity | 1995 |
An adult-type metachromatic leukodystrophy caused by substitution of serine for glycine-122 in arylsulfatase A.
Topics: Adult; Animals; Base Sequence; Cell Line; Cerebroside-Sulfatase; Chlorocebus aethiops; DNA Mutational Analysis; DNA Primers; Female; Glycine; Humans; Kidney; Leukodystrophy, Metachromatic; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Polymorphism, Restriction Fragment Length; Serine; Transfection | 1993 |
Effects of diet-induced hyperthreoninemia. II). Tissue and extracellular amino acid levels in the brain.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Cerebral Cortex; Diet; Glutamates; Glutamic Acid; Glycine; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord; Threonine | 1994 |
Neuroleptic effects on serine and glycine metabolism.
Topics: Adult; Animals; Antipsychotic Agents; Brain; Cytosol; Female; Fluphenazine; Glycine; Glycine Hydroxymethyltransferase; Haloperidol; Humans; Liver; Male; Mitochondria, Liver; Psychiatric Status Rating Scales; Rabbits; Rats; Rats, Sprague-Dawley; Schizophrenia; Schizophrenic Psychology; Serine | 1993 |
A comparison of the effects of ethanol and the competitive glycine antagonist 7-chlorokynurenic acid on N-methyl-D-aspartic acid-induced neurotransmitter release from rat hippocampal slices.
Topics: Animals; Dose-Response Relationship, Drug; Ethanol; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; N-Methylaspartate; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Sprague-Dawley; Serine | 1994 |
Intrinsic primary, secondary, and solvent kinetic isotope effects on the reductive half-reaction of D-amino acid oxidase: evidence against a concerted mechanism.
Topics: Alanine; Catalysis; D-Amino-Acid Oxidase; Deuterium; Glycine; Kinetics; Serine; Solvents; Structure-Activity Relationship; Tritium | 1994 |
pH and kinetic isotope effects on the oxidative half-reaction of D-amino-acid oxidase.
Topics: Alanine; Animals; D-Amino-Acid Oxidase; Glycine; Hydrogen-Ion Concentration; Isotopes; Kinetics; Oxidation-Reduction; Rabbits; Serine; Substrate Specificity | 1994 |
Dietary pectin's effect on ileal and fecal amino acid digestibility and exocrine pancreatic secretions in growing pigs.
Topics: alpha-Amylases; Amino Acids; Animals; Aspartic Acid; Dietary Fiber; Digestion; Feces; Glutamates; Glutamic Acid; Glycine; Ileum; Male; Pancreas; Pancreatic Juice; Pectins; Phenylalanine; Proline; Serine; Swine; Threonine; Trypsin; Valine | 1994 |
Dextrorphan inhibits the release of excitatory amino acids during spinal cord ischemia.
Topics: Amino Acids; Animals; Aspartic Acid; Dextrorphan; Evoked Potentials; Evoked Potentials, Somatosensory; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ischemia; Microdialysis; Motor Cortex; Neurotransmitter Agents; Receptors, Amino Acid; Serine; Spinal Cord; Swine | 1994 |
Variability of clinical phenotype in a large Alport family with Gly 1143 Ser change of collagen alpha 5(IV)-chain.
Topics: Adolescent; Adult; Aged; Base Sequence; Collagen; DNA; Female; Genotype; Glycine; Humans; Italy; Male; Middle Aged; Molecular Sequence Data; Mutation; Nephritis, Hereditary; Pedigree; Phenotype; Serine | 1994 |
Atomic force microscopy and molecular modeling of protein and peptide binding to calcite.
Topics: Animals; Aspartic Acid; Calcium Carbonate; Glycine; Microscopy; Microscopy, Electron, Scanning; Models, Molecular; Molecular Weight; Nuclear Energy; Ostreidae; Protein Binding; Serine | 1994 |
A single base mutation in the type II procollagen gene (COL2A1) that converts glycine alpha 1-247 to serine in a family with late-onset spondyloepiphyseal dysplasia.
Topics: Adult; Age of Onset; Amino Acid Sequence; Base Sequence; Female; Glycine; Humans; Male; Molecular Sequence Data; Osteochondrodysplasias; Pedigree; Point Mutation; Polymerase Chain Reaction; Procollagen; Serine | 1994 |
Anticonvulsant effects of the glycine/NMDA receptor ligands D-cycloserine and D-serine but not R-(+)-HA-966 in amygdala-kindled rats.
Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Cycloserine; Dizocilpine Maleate; Electric Stimulation; Epilepsy, Complex Partial; Female; Glycine; Kindling, Neurologic; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine | 1994 |
Energetic aspects of intramolecular coupling between the nucleotide binding site and the distal switch II region of the yeast RAS2 protein.
Topics: Binding Sites; Escherichia coli; Fungal Proteins; Glycine; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Diphosphate; Guanylyl Imidodiphosphate; ras Proteins; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Structure-Activity Relationship; Temperature; Thermodynamics | 1994 |
Placental and fetal serine fluxes at midgestation in the fetal lamb.
Topics: Animals; Carbon Dioxide; Female; Fetal Blood; Fetus; Gestational Age; Glycine; Osmolar Concentration; Placenta; Pregnancy; Serine; Sheep | 1994 |
[In vitro NMR spectroscopy of healthy, pathologically changed and carcinomatous breast tissue samples correlated with histological findings].
Topics: Breast; Breast Diseases; Breast Neoplasms; Diagnosis, Differential; Fatty Acids; Female; Glucose; Glycine; Humans; In Vitro Techniques; Inositol; Magnetic Resonance Spectroscopy; Serine; Sucrose; Threonine | 1994 |
Mutagenesis of the cyclic AMP receptor protein of Escherichia coli: targeting positions 83, 127 and 128 of the cyclic nucleotide binding pocket.
Topics: Base Sequence; beta-Galactosidase; Binding Sites; Cross-Linking Reagents; Cyclic AMP; Cysteine; Dithionitrobenzoic Acid; Escherichia coli; Glycine; Isoleucine; Molecular Sequence Data; Mutagenesis; Receptors, Cyclic AMP; Serine; Structure-Activity Relationship; Threonine; Transcription, Genetic | 1994 |
A Gly859Ser substitution in the triple helical domain of the alpha 2 chain of type I collagen resulting in osteogenesis imperfecta type III in two unrelated individuals.
Topics: Adult; Base Sequence; Child, Preschool; Collagen; DNA Mutational Analysis; DNA Primers; DNA, Single-Stranded; Female; Glycine; Humans; Male; Molecular Sequence Data; Nucleic Acid Conformation; Osteogenesis Imperfecta; Point Mutation; Polymorphism, Genetic; Procollagen; Restriction Mapping; Serine | 1994 |
Use of denaturing gradient gel electrophoresis to identify mutant sequences in the beta-glucocerebrosidase gene.
Topics: Base Sequence; Child, Preschool; DNA Mutational Analysis; DNA Primers; Electrophoresis, Polyacrylamide Gel; Female; Gaucher Disease; Glucosylceramidase; Glycine; Humans; Molecular Sequence Data; Nucleic Acid Denaturation; Nucleic Acid Heteroduplexes; Point Mutation; Polymerase Chain Reaction; Pseudogenes; Serine | 1994 |
Serine for glycine substitutions in type I collagen in two cases of type IV osteogenesis imperfecta (OI). Additional evidence for a regional model of OI pathophysiology.
Topics: Amino Acid Sequence; Base Sequence; Child; Child, Preschool; Collagen; Cyanogen Bromide; Female; Glycine; Humans; Molecular Sequence Data; Mutation; Nucleic Acid Hybridization; Oligodeoxyribonucleotides; Osteogenesis Imperfecta; Peptide Fragments; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Procollagen; Protein Denaturation; RNA, Messenger; Serine | 1993 |
An evaluation of the role of extracellular amino acids in the delayed neurodegeneration induced by quinolinic acid in the rat striatum.
Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Corpus Striatum; Dialysis; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Male; Microinjections; Nerve Degeneration; Niacin; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Serine; Threonine | 1993 |
Feedback inhibition of fully unadenylylated glutamine synthetase from Salmonella typhimurium by glycine, alanine, and serine.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Chromatography, Affinity; Crystallization; Feedback; Fourier Analysis; Glutamate-Ammonia Ligase; Glycine; Kinetics; Models, Molecular; Protein Binding; Protein Conformation; Salmonella typhimurium; Serine; X-Ray Diffraction | 1993 |
High residual arylsulfatase A (ARSA) activity in a patient with late-infantile metachromatic leukodystrophy.
Topics: Alleles; Animals; Base Sequence; Cells, Cultured; Cerebroside-Sulfatase; Cricetinae; DNA Mutational Analysis; Fluorescent Antibody Technique; Frameshift Mutation; Genotype; Glycine; Humans; Infant; Leukodystrophy, Metachromatic; Male; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodendroglia; Phenotype; Point Mutation; Rhodamines; Serine; Sulfoglycosphingolipids | 1993 |
Mutations in the consensus ATP-binding sites of XcpR and PilB eliminate extracellular protein secretion and pilus biogenesis in Pseudomonas aeruginosa.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Amino Acid Sequence; Bacterial Proteins; Base Sequence; beta-Lactamases; Cell Compartmentation; Consensus Sequence; Fimbriae, Bacterial; Glycine; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oxidoreductases; Pseudomonas aeruginosa; Pseudomonas Phages; Serine; Transformation, Genetic | 1993 |
Homozygosity for a mutation in the lipoprotein lipase gene (Gly139-->Ser) causes chylomicronaemia in a boy of Spanish descent.
Topics: Adolescent; Base Sequence; Chylomicrons; DNA; Female; Glycine; Homozygote; Humans; Lipoprotein Lipase; Male; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Pedigree; Serine; Spain | 1994 |
Sheep haemoglobin I or beta B13(A10)Gly-->Ser: an example of a CpG mutation in vertebrates. Characterization using FAB-mass spectrometry and amino acid sequencing.
Topics: Amino Acid Sequence; Animals; Globins; Glycine; Hemoglobins; Hemoglobins, Abnormal; Molecular Sequence Data; Mutation; Serine; Sheep; Spectrometry, Mass, Fast Atom Bombardment | 1993 |
K-ras-2 topographic genotyping of pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Alanine; Arginine; Aspartic Acid; Codon; Cysteine; DNA, Neoplasm; Exons; Forecasting; Genes, ras; Genotype; Glycine; Humans; Leucine; Mutation; Pancreas; Pancreatic Neoplasms; Serine; Survival Rate; Valine | 1994 |
Self-assembly of collagen I from a proband homozygous for a mutation that substituted serine for glycine at position 661 in the alpha 2(I) chain. Possible relationship between the effects of mutations on critical concentration and the severity of the phen
Topics: Amino Acid Sequence; Cells, Cultured; Collagen; Female; Fibroblasts; Glycine; Humans; Kinetics; Macromolecular Substances; Microscopy, Electron; Phenotype; Point Mutation; Procollagen; Procollagen N-Endopeptidase; Protein Processing, Post-Translational; Serine; Skin | 1994 |
Isolation and refolding of H-ras from inclusion bodies of Escherichia coli: refold procedure and comparison of refolded and soluble H-ras.
Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Escherichia coli; Glycerol; Glycine; Guanosine Diphosphate; Guanosine Triphosphate; Magnetic Resonance Spectroscopy; Protein Folding; Proto-Oncogene Proteins p21(ras); Serine; Solubility; Temperature | 1994 |
A study of the tryptophan synthase catalysed H/D exchange of the alpha-protons of amino acids.
Topics: Alanine; Glycine; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Protons; Serine; Substrate Specificity; Tryptophan Synthase | 1994 |
Mutation of glycine receptor subunit creates beta-alanine receptor responsive to GABA.
Topics: Amino Acid Sequence; Animals; beta-Alanine; Female; gamma-Aminobutyric Acid; Glycine; Ion Channel Gating; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Receptors, GABA; Receptors, Glycine; Serine; Taurine; Xenopus | 1993 |
Sodium-dependent release of exogenous glycine from preloaded rat hippocampal synaptosomes.
Topics: Animals; Cations; Choline; Glycine; Hippocampus; Kinetics; Male; Ouabain; Rats; Rats, Sprague-Dawley; Serine; Sodium; Synaptosomes; Tetrodotoxin; Tritium; Veratridine | 1993 |
Function of the active-site lysine in Escherichia coli serine hydroxymethyltransferase.
Topics: Arginine; Base Sequence; Binding Sites; Escherichia coli; Glycine; Glycine Hydroxymethyltransferase; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Point Mutation; Recombinant Proteins; Serine; Spectrum Analysis; Structure-Activity Relationship | 1993 |
Cytochrome c oxidase mutations in Leber hereditary optic neuropathy.
Topics: Amino Acid Sequence; Animals; Base Sequence; Biological Evolution; Codon; Conserved Sequence; DNA Primers; DNA, Mitochondrial; Electron Transport Complex IV; Glycine; Humans; Macromolecular Substances; Molecular Sequence Data; Optic Atrophies, Hereditary; Point Mutation; Polymerase Chain Reaction; Restriction Mapping; Serine | 1993 |
Cloning of Chinese hamster DNA topoisomerase I cDNA and identification of a single point mutation responsible for camptothecin resistance.
Topics: Amino Acid Sequence; Animals; Arabidopsis; Base Sequence; Camptothecin; Cell Line; Cloning, Molecular; Conserved Sequence; Cricetinae; Cricetulus; DNA Primers; DNA Topoisomerases, Type I; DNA, Complementary; Drosophila melanogaster; Drug Resistance; Glycine; Humans; Lung; Mice; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Serine; Viruses | 1993 |
Effects of diet-induced hyperthreoninemia. I). Amino acid levels in the central nervous system and peripheral tissues.
Topics: Alcohol Oxidoreductases; Amino Acids; Animals; Central Nervous System; Chromatography, High Pressure Liquid; Glycine; Liver; Male; Muscles; Rats; Rats, Sprague-Dawley; Serine; Threonine; Threonine Dehydratase | 1993 |
Serine and glycine metabolism in schizophrenic patients.
Topics: Adult; Glycine; Glycine Hydroxymethyltransferase; Humans; Male; N-Methylaspartate; Schizophrenia; Serine | 1993 |
13C NMR analysis of intercompartmental flow of one-carbon units into choline and purines in Saccharomyces cerevisiae.
Topics: Adenine; Carbon Isotopes; Choline; Formates; Genotype; Glycine; Guanine; Magnetic Resonance Spectroscopy; Models, Biological; Purines; Saccharomyces cerevisiae; Serine | 1994 |
Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors.
Topics: Amino Acid Sequence; Animals; Arginine; Binding Sites; Conserved Sequence; Glycine; Humans; Information Systems; Molecular Sequence Data; Phylogeny; RNA Precursors; RNA Splicing; RNA-Binding Proteins; Sequence Homology, Amino Acid; Serine | 1993 |
Recurrent pancreatitis and chylomicronemia in an extended Dutch kindred is caused by a Gly154-->Ser substitution in lipoprotein lipase.
Topics: Adult; Base Sequence; Cell Line; Chylomicrons; DNA; Glycine; Humans; Lipoprotein Lipase; Male; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Netherlands; Pancreatitis; Recurrence; RNA Splicing; RNA, Messenger; Serine; Transfection | 1993 |
Glycosylation of two recombinant human uterine tissue plasminogen activator variants carrying an additional N-glycosylation site in the epidermal-growth-factor-like domain.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Female; Genetic Variation; Glycine; Glycopeptides; Glycosylation; Humans; Mass Spectrometry; Methylation; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oligosaccharides; Peptide Mapping; Protein Processing, Post-Translational; Recombinant Proteins; Serine; Tissue Plasminogen Activator; Tyrosine; Uterus | 1994 |
SOD1 missense mutation in an Italian family with ALS.
Topics: Adult; Amyotrophic Lateral Sclerosis; Base Sequence; Chromosomes, Human, Pair 21; DNA; DNA Primers; Family; Female; Glycine; Humans; Italy; Male; Middle Aged; Molecular Sequence Data; Pedigree; Point Mutation; Polymerase Chain Reaction; Serine; Superoxide Dismutase | 1994 |
A single amino acid switch within the "hinge" region of the tryptophan synthase beta subunit of Escherichia coli that leads to diminished association with alpha subunit and arrested conversion of ESII to product.
Topics: Arginine; Catalysis; Escherichia coli; Glycine; Mutation; Polyethylene Glycols; Protein Conformation; Pyridoxal; Schiff Bases; Serine; Spectrometry, Fluorescence; Substrate Specificity; Tryptophan; Tryptophan Synthase | 1993 |
beta-Hexosaminidase isozymes from cells cotransfected with alpha and beta cDNA constructs: analysis of the alpha-subunit missense mutation associated with the adult form of Tay-Sachs disease.
Topics: Adult; Animals; Base Sequence; beta-N-Acetylhexosaminidases; Blotting, Western; Cells, Cultured; Chromatography, High Pressure Liquid; DNA Mutational Analysis; Genotype; Glycine; Haplorhini; Hexosaminidase A; Hot Temperature; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenotype; Point Mutation; Protein Denaturation; Protein Folding; Serine; Tay-Sachs Disease; Transfection | 1993 |
Development of primary culture of ovine fetal hepatocytes for studies of amino acid metabolism and insulinlike growth factors.
Topics: Amino Acids; Animals; Cell Division; Cell Separation; Cells, Cultured; DNA; Female; Fetus; Gene Expression; Glucose; Glycine; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Lactates; Liver; Pregnancy; RNA, Messenger; Serine; Sheep; Thymidine | 1993 |
Metabolism and transport of maternal serine by the ovine placenta: glycine production and absence of serine transport into the fetus.
Topics: Animals; Biological Transport, Active; Female; Fetal Blood; Fetus; Glycine; Leucine; Maternal-Fetal Exchange; Placenta; Pregnancy; Serine; Sheep | 1993 |
The hepatitis C virus encodes a serine protease involved in processing of the putative nonstructural proteins from the viral polyprotein precursor.
Topics: Animals; Base Sequence; Cells, Cultured; Glycine; Hepacivirus; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Protein Biosynthesis; Protein Precursors; Protein Processing, Post-Translational; RNA, Viral; Serine; Serine Endopeptidases; Transcription, Genetic; Viral Nonstructural Proteins | 1993 |
Computer modeling studies on the binding of 2',5'-linked dinucleoside phosphates to ribonuclease T1-influence of subsite interactions on the substrate specificity.
Topics: Binding Sites; Computer Simulation; Dinucleoside Phosphates; Exoribonucleases; Glycine; Guanosine Monophosphate; Hydrogen Bonding; Molecular Conformation; Protein Conformation; Serine; Substrate Specificity | 1993 |
An E. coli RuvC mutant defective in cleavage of synthetic Holliday junctions.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; Codon; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Glycine; Molecular Sequence Data; Mutation; Nucleotidyltransferases; Plasmids; Polymerase Chain Reaction; Rec A Recombinases; Recombinant Proteins; Serine; Structure-Activity Relationship; Transposases; Ultraviolet Rays | 1993 |
Equilibrium dissociation and unfolding of nucleoside diphosphate kinase from Dictyostelium discoideum. Role of proline 100 in the stability of the hexameric enzyme.
Topics: Amino Acid Sequence; Animals; Base Sequence; Chromatography, Gel; Circular Dichroism; Dictyostelium; Enzyme Stability; Glycine; Kinetics; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleoside-Diphosphate Kinase; Oligodeoxyribonucleotides; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Recombinant Proteins; Serine; Spectrophotometry, Ultraviolet; Urea | 1993 |
A familial/genetic study of plasma serine and glycine concentrations.
Topics: Dopamine; Female; gamma-Aminobutyric Acid; Glucose; Glutamates; Glycine; Humans; Internal-External Control; Male; Mitochondria; Psychotic Disorders; Schizophrenia; Serine | 1993 |
Identification of type I collagen gene (COL1A2) mutations in nonlethal osteogenesis imperfecta.
Topics: Amino Acid Sequence; Base Sequence; Cell Line; Codon; Collagen; Female; Fibroblasts; Glycine; Humans; Infant, Newborn; Male; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Osteogenesis Imperfecta; Point Mutation; RNA, Messenger; Serine; Skin; Valine | 1993 |
Isolation and characterization of male flower cDNAs from maize.
Topics: Amino Acid Sequence; Base Sequence; DNA, Complementary; Gene Expression; Gene Library; Genes, Plant; Glycine; Molecular Sequence Data; Peptides; Plant Proteins; Proline; Protein Sorting Signals; RNA, Messenger; Serine; Zea mays | 1993 |
Endogenous D-serine in rat brain: N-methyl-D-aspartate receptor-related distribution and aging.
Topics: Aging; Animals; Brain; Glycine; Kidney; Liver; Male; Organ Specificity; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism | 1993 |
The clinical features of spondyloepiphyseal dysplasia congenita resulting from the substitution of glycine 997 by serine in the alpha 1(II) chain of type II collagen.
Topics: Collagen; Ear, Middle; Female; Follow-Up Studies; Glycine; Hearing Loss, Conductive; Humans; Infant, Newborn; Osteochondrodysplasias; Point Mutation; Serine | 1993 |
Methionine toxicity in the rat in relation to hepatic accumulation of S-adenosylmethionine: prevention by dietary stimulation of the hepatic transsulfuration pathway.
Topics: Amino Acids; Animals; Body Weight; Diet; Feeding Behavior; Glycine; Kidney; Liver; Male; Methionine; Muscles; Rats; Rats, Wistar; S-Adenosylmethionine; Serine | 1993 |
Abnormal serine-glycine metabolism in the brains of schizophrenics.
Topics: Aged; Cytosol; Dominance, Cerebral; Female; Glycine; Humans; Male; Middle Aged; Mitochondria; Schizophrenia; Schizophrenic Psychology; Serine; Temporal Lobe | 1993 |
Moderately severe osteogenesis imperfecta associated with substitutions of serine for glycine in the alpha 1(I) chain of type I collagen.
Topics: Child; Collagen; DNA Mutational Analysis; Female; Glycine; Humans; Osteogenesis Imperfecta; Point Mutation; Procollagen; Radiography; Serine | 1993 |
Modulation of the heat shock response by one-carbon metabolism in Escherichia coli.
Topics: 2,4-Dinitrophenol; Adaptation, Biological; Alleles; Cloning, Molecular; Dinitrophenols; Escherichia coli; Genes, Bacterial; Genetic Complementation Test; Glycine; Glycine Hydroxymethyltransferase; Heat-Shock Proteins; Hot Temperature; Methionine; Mutagenesis; Phenotype; Serine; Tetrahydrofolates | 1993 |
Altered muropeptide composition in Staphylococcus aureus strains with an inactivated femA locus.
Topics: Amino Acid Sequence; Cell Wall; Genes, Bacterial; Glycine; Molecular Sequence Data; Muramic Acids; Mutagenesis, Insertional; Oligopeptides; Peptidoglycan; Protein Conformation; Serine; Staphylococcus aureus | 1993 |
A serine to glycine substitution at position 9 in the extracellular N-terminal part of the dopamine D3 receptor protein: no role in the genetic predisposition to bipolar affective disorder.
Topics: Alleles; Amino Acid Sequence; Bipolar Disorder; Female; Gene Frequency; Genotype; Glycine; Humans; Male; Peptide Chain Termination, Translational; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Risk Factors; Serine | 1993 |
A novel alpha-ketoglutarate reductase activity of the serA-encoded 3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its possible implications for human 2-hydroxyglutaric aciduria.
Topics: Alcohol Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Carbohydrate Dehydrogenases; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Glutarates; Glyceric Acids; Glycine; Humans; Ketoglutaric Acids; Kinetics; Models, Chemical; Oxidation-Reduction; Phosphoglycerate Dehydrogenase; Pyridoxal Phosphate; Pyruvates; Serine | 1996 |
Pathways of serine and glycine metabolism in primary culture of ovine fetal hepatocytes.
Topics: Animals; Carbon Radioisotopes; Cells, Cultured; Culture Media; Female; Glycine; Linear Models; Liver; Pregnancy; Serine; Sheep; Time Factors | 1995 |
Amino-acid-type-selective triple-resonance experiments.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Calcium-Binding Proteins; Carbon; Carrier Proteins; Cysteine; Glycine; Image Enhancement; Isoleucine; Magnetic Resonance Spectroscopy; Methionine; Microfilament Proteins; Nitrogen; Serine; Valine | 1996 |
Generation of diverse single-chain proteins using a universal (Gly4-Ser)3 encoding oligonucleotide.
Topics: Base Sequence; Codon; Electrophoresis, Agar Gel; Glycine; Molecular Sequence Data; Nucleic Acid Hybridization; Oligonucleotides; Oligopeptides; Peptide Biosynthesis; Peptides; Polymerase Chain Reaction; Serine | 1995 |
Evidence for intracellular partitioning of serine and glycine metabolism in Chinese hamster ovary cells.
Topics: Amino Acid Oxidoreductases; Animals; Carrier Proteins; CHO Cells; Cricetinae; Culture Media; Cytosol; Glycine; Glycine Hydroxymethyltransferase; Mitochondria; Multienzyme Complexes; Serine; Transferases | 1996 |
Type II human complement C2 deficiency. Allele-specific amino acid substitutions (Ser189 --> Phe; Gly444 --> Arg) cause impaired C2 secretion.
Topics: Alleles; Amino Acid Sequence; Animals; Arginine; Base Sequence; Cells, Cultured; Cloning, Molecular; Complement C2; Cosmids; DNA; Female; Fibroblasts; Fluorescent Antibody Technique, Indirect; Glycine; Humans; L Cells; Male; Mice; Molecular Sequence Data; Nuclear Family; Oligodeoxyribonucleotides; Pedigree; Phenylalanine; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Recombinant Proteins; Reference Values; Serine; Skin; Transfection | 1996 |
The Gly40Ser mutation in the human glucagon receptor gene associated with NIDDM results in a receptor with reduced sensitivity to glucagon.
Topics: Amino Acid Sequence; Animals; Cell Line; Cricetinae; Cyclic AMP; Diabetes Mellitus, Type 2; Exons; Glucagon; Glycine; Humans; Insulin; Insulin Secretion; Insulinoma; Kidney; Kinetics; Molecular Sequence Data; Pancreatic Neoplasms; Point Mutation; Protein Structure, Secondary; Rats; Receptors, Glucagon; Recombinant Proteins; Serine; Transfection | 1996 |
A nucleoside diphosphate kinase A (nm23-H1) serine 120-->glycine substitution in advanced stage neuroblastoma affects enzyme stability and alters protein-protein interaction.
Topics: Base Sequence; Cross-Linking Reagents; DNA Primers; Enzyme Stability; Glutaral; Glycine; Hot Temperature; Humans; Isoenzymes; Kinetics; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Mutagenesis, Site-Directed; Neoplasm Staging; Neuroblastoma; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Point Mutation; Polymerase Chain Reaction; Protein Denaturation; Recombinant Proteins; Serine; Thermodynamics; Transcription Factors | 1996 |
The Gly74-->Ser and Ser3-->Ala mutations in Rhodobacter sphaeroides Y thioredoxin: effects on active site reactivity and protein interaction.
Topics: Alanine; Amino Acid Sequence; Bacteriophage T7; Base Sequence; Binding Sites; DNA, Recombinant; Glycine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Disulfide Reductase (Glutathione); Rhodobacter sphaeroides; Serine; Thioredoxins; Viral Proteins | 1996 |
Two novel point mutations in the lecithin:cholesterol acyltransferase (LCAT) gene resulting in LCAT deficiency: LCAT (G873 deletion) and LCAT (Gly344-->Ser).
Topics: Adult; Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Cell Line; Cricetinae; Gene Deletion; Glycine; Humans; Lecithin Cholesterol Acyltransferase Deficiency; Lipoproteins; Male; Molecular Sequence Data; Mutagenesis, Site-Directed; Pedigree; Phosphatidylcholine-Sterol O-Acyltransferase; Point Mutation; Polymorphism, Restriction Fragment Length; Serine | 1995 |
High levels of glycine and serine as a cause of the seizure symptoms of cavernous angiomas?
Topics: Adult; Brain Chemistry; Ethanolamine; Ethanolamines; Female; Glycine; Hemangioma, Cavernous; Humans; Male; Middle Aged; Seizures; Serine | 1996 |
hnRNP A1 selectively interacts through its Gly-rich domain with different RNA-binding proteins.
Topics: Amino Acid Sequence; Arginine; Base Sequence; Binding Sites; Glycine; Heterogeneous Nuclear Ribonucleoprotein A1; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Heterogeneous-Nuclear Ribonucleoproteins; Models, Molecular; Molecular Sequence Data; Nucleic Acids; Phenols; Protein Conformation; Recombinant Fusion Proteins; Ribonucleoproteins; RNA Splicing; RNA-Binding Proteins; Serine; Structure-Activity Relationship; Substrate Specificity; Yeasts | 1996 |
Lack of association between the Gly40Ser polymorphism in the glucagon receptor gene and NIDDM in Finland.
Topics: Alleles; Amino Acid Sequence; Base Sequence; Diabetes Mellitus, Type 2; DNA Primers; Finland; France; Gene Frequency; Glucose Intolerance; Glycine; Humans; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Receptors, Glucagon; Reference Values; Serine | 1995 |
Substitution of serine for glycine-91 in the HXGH motif of CTP:phosphocholine cytidylyltransferase implicates this motif in CTP binding.
Topics: Animals; Base Sequence; Cell Line; Choline-Phosphate Cytidylyltransferase; Chymotrypsin; Glycine; Hydrolysis; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleotidyltransferases; Protein Denaturation; Serine; Substrate Specificity; Urea | 1996 |
Absence of the Gly40-Ser mutation in the glucagon receptor among diabetic patients in the Netherlands.
Topics: Aged; Cohort Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gene Frequency; Glycine; Humans; Middle Aged; Netherlands; Point Mutation; Receptors, Glucagon; Reference Values; Serine | 1995 |
Serine and glycine metabolism in hepatocytes from mid gestation fetal lambs.
Topics: Amino Acids; Animals; Cells, Cultured; Glycine; Glycine Hydroxymethyltransferase; Liver; Serine; Sheep | 1996 |
Role of mitochondrial DNA tRNA leucine and glucagon receptor missense mutations in Utah white diabetic patients.
Topics: Alleles; Disease Susceptibility; DNA, Mitochondrial; Europe; Female; Glucose Tolerance Test; Glycine; Humans; Male; Middle Aged; Nuclear Family; Point Mutation; Receptors, Glucagon; Reference Values; RNA, Transfer, Leu; Serine; Utah | 1996 |
Gly40Ser substitution in the glucagon receptor is rarely involved in the pathogenesis of NIDDM in Japanese patients.
Topics: Base Sequence; Codon; Diabetes Mellitus, Type 2; DNA Primers; Female; Glycine; Humans; Japan; Male; Middle Aged; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, Glucagon; Restriction Mapping; Serine | 1996 |
Changes in the intracellular free amino acid pool in human saphenous vein tissue culture.
Topics: Aged; Alanine; Amino Acids; Asparagine; Aspartic Acid; Culture Techniques; Cytosol; Glutamic Acid; Glutamine; Glycine; Humans; Middle Aged; Proline; Saphenous Vein; Serine; Taurine | 1996 |
Unaccustomed high-mileage vs intensity training-related changes in performance and serum amino acid levels.
Topics: Adult; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cystine; Erythrocyte Count; Exercise Test; Fatigue; Glycine; Hematocrit; Hemoglobins; Humans; Lactates; Leukocyte Count; Lysine; Methionine; Phenylalanine; Physical Endurance; Prospective Studies; Running; Serine; Taurine; Tryptophan; Tyrosine | 1996 |
Variable hyperhomocysteinaemia phenotype in heterozygotes for the Gly307Ser mutation in cystathionine beta-synthase.
Topics: Adolescent; Adult; Amino Acid Sequence; Cystathionine beta-Synthase; Female; Glycine; Heterozygote; Homocystinuria; Humans; Male; Molecular Sequence Data; Mutation; Phenotype; Serine | 1996 |
3-Phosphoglycerate dehydrogenase deficiency: an inborn error of serine biosynthesis.
Topics: Amino Acid Metabolism, Inborn Errors; Carbohydrate Dehydrogenases; Fibroblasts; Glycine; Humans; Infant; Male; Microcephaly; Phosphoglycerate Dehydrogenase; Psychomotor Disorders; Serine | 1996 |
Plasma concentrations of excitatory amino acids, serine, glycine, taurine and histidine in major depression.
Topics: Adult; Analysis of Variance; Depressive Disorder; Excitatory Amino Acids; Female; Glycine; Histidine; Humans; Male; Serine; Taurine | 1995 |
Amino-acid-dependent modulation of amino acid transport in Xenopus laevis oocytes.
Topics: Amino Acid Transport Systems; Amino Acids; Animals; Arginine; Biological Transport; Carrier Proteins; Female; Glutamic Acid; Glutamine; Glycine; Oocytes; Phenylalanine; Serine; Sodium; Xenopus laevis | 1996 |
Dopamine D3 receptor Gly9/Ser9 polymorphism and schizophrenia: no increased frequency of homozygosity in German familial cases.
Topics: Adult; Alleles; Codon, Terminator; DNA Mutational Analysis; Female; Gene Frequency; Germany; Glycine; Homozygote; Humans; Male; Middle Aged; Polymorphism, Genetic; Psychiatric Status Rating Scales; Receptors, Dopamine D2; Receptors, Dopamine D3; Risk Factors; Schizophrenia; Schizophrenic Psychology; Serine; Terminator Regions, Genetic | 1996 |
Complete deficiency of plasma lecithin-cholesterol acyltransferase (LCAT) activity due to a novel homozygous mutation (Gly-30-Ser) in the LCAT gene.
Topics: Adult; Female; Genetic Carrier Screening; Glycine; Homozygote; Humans; Lipids; Male; Mutation; Pedigree; Phosphatidylcholine-Sterol O-Acyltransferase; Serine | 1996 |
Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells.
Topics: Alanine; Amino Acid Sequence; Animals; Breast Neoplasms; Cell Division; Chemotaxis; Drosophila; Female; Glycine; Histidine; Humans; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Mutagenesis, Site-Directed; Neuroblastoma; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Phosphorylation; Polymerase Chain Reaction; Proline; Recombinant Proteins; Serine; Transcription Factors; Transfection; Tumor Cells, Cultured | 1996 |
13C nuclear magnetic resonance detection of interactions of serine hydroxymethyltransferase with C1-tetrahydrofolate synthase and glycine decarboxylase complex activities in Arabidopsis.
Topics: Amino Acid Oxidoreductases; Aminohydrolases; Arabidopsis; Binding Sites; Carbon Isotopes; Formate-Tetrahydrofolate Ligase; Glycine; Glycine Decarboxylase Complex; Glycine Dehydrogenase (Decarboxylating); Glycine Hydroxymethyltransferase; Kinetics; Magnetic Resonance Spectroscopy; Methotrexate; Methylenetetrahydrofolate Dehydrogenase (NADP); Multienzyme Complexes; Serine; Sulfanilamide; Sulfanilamides | 1996 |
Specific induction by glycine of the gene for the P-subunit of glycine decarboxylase from Saccharomyces cerevisiae.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Base Sequence; beta-Galactosidase; Blotting, Northern; Cloning, Molecular; Enzyme Induction; Glycine; Glycine Decarboxylase Complex; Glycine Dehydrogenase (Decarboxylating); Lac Operon; Molecular Sequence Data; Promoter Regions, Genetic; Protein Structure, Secondary; Restriction Mapping; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Deletion; Sequence Homology, Nucleic Acid; Serine; Transcription Factors | 1996 |
Glutathione content as an indicator for the presence of metabolic pathways of amino acids in astroglial cultures.
Topics: Amino Acids; Animals; Animals, Newborn; Astrocytes; Biomarkers; Brain; Cell Survival; Cells, Cultured; Glucose; Glutathione; Glycine; Kinetics; Nerve Tissue Proteins; Rats; Rats, Wistar; Serine; Time Factors | 1996 |
High level expression of the NMDAR1 glutamate receptor subunit in electroporated COS cells.
Topics: Animals; beta-Galactosidase; Binding, Competitive; Calcium; Cell Line; Chlorocebus aethiops; COS Cells; Electroporation; Excitatory Amino Acid Antagonists; Glycine; Humans; Kidney; Kinetics; Kynurenic Acid; Macromolecular Substances; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Serine; Stereoisomerism; Transfection | 1996 |
In vivo elevation of extracellular potassium in the rat amygdala increases extracellular glutamate and aspartate and damages neurons.
Topics: Amygdala; Animals; Aspartic Acid; Brain Edema; Extracellular Space; Glutamic Acid; Glutamine; Glycine; Kinetics; Male; Microdialysis; Neurons; Potassium; Potassium Chloride; Rats; Rats, Wistar; Serine; Taurine | 1996 |
A postmortem study of glycine and its potential precursors in chronic schizophrenics.
Topics: Adult; Aged; Brain Chemistry; Chromatography, High Pressure Liquid; Chronic Disease; Female; Glycine; Humans; Indicators and Reagents; Male; Middle Aged; p-Dimethylaminoazobenzene; Postmortem Changes; Schizophrenia; Serine; Threonine | 1996 |
Role of cytosolic serine hydroxymethyltransferase in one-carbon metabolism in Neurospora crassa.
Topics: Carbon; Choline; Cytosol; Formates; Glucose; Glycine; Glycine Hydroxymethyltransferase; Magnetic Resonance Spectroscopy; Mitochondria; Neurospora crassa; Serine | 1996 |
Comparison of leucine, serine and glycine transport across the ovine placenta.
Topics: Animals; Biological Transport; Blood Flow Velocity; Female; Fetal Blood; Glycine; Kinetics; Leucine; Maternal-Fetal Exchange; Placenta; Pregnancy; Serine; Sheep; Umbilical Arteries; Umbilical Veins; Uterus | 1996 |
Absence of association between the Gly40-->Ser mutation in the human glucagon receptor and Japanese patients with non-insulin-dependent diabetes mellitus or impaired glucose tolerance.
Topics: Adult; Aged; Asian People; Codon; Diabetes Mellitus, Type 2; Exons; Female; Glucose Intolerance; Glycine; Humans; Japan; Male; Middle Aged; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Receptors, Glucagon; Serine | 1996 |
Modified ligands to FA and FB in photosystem I. Proposed chemical rescue of a [4Fe-4S] cluster with an external thiolate in alanine, glycine, and serine mutants of PsaC.
Topics: Alanine; Bacterial Proteins; Cytochromes; Cytochromes f; Electron Spin Resonance Spectroscopy; Electron Transport; Glycine; Iron-Sulfur Proteins; Kinetics; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Photosynthetic Reaction Center Complex Proteins; Photosystem I Protein Complex; Serine; Structure-Activity Relationship | 1996 |
Glucose contribution to nucleic acid base synthesis in proliferating hepatoma cells: a glycine-biosynthesis-mediated pathway.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cells, Cultured; Cycloserine; Enzyme Inhibitors; Glucose; Glycine; Glycogen; Glycolysis; Insulin; Lactic Acid; Nucleic Acids; Nucleotides; Proteins; Rats; Rats, Inbred Strains; Serine; Transaminases | 1995 |
Involvement of two amino acid residues in the loop region of Bacillus thuringiensis Cry1Ab toxin in toxicity and binding to Lymantria dispar.
Topics: Animals; Bacillus thuringiensis; Bacillus thuringiensis Toxins; Bacterial Proteins; Bacterial Toxins; Binding, Competitive; Digestive System; Dose-Response Relationship, Drug; Endotoxins; Glycine; Hemolysin Proteins; Manduca; Moths; Mutagenesis, Site-Directed; Protein Binding; Serine; Structure-Activity Relationship | 1996 |
Hypothesis: glucagon receptor glycine to serine missense mutation contributes to one in 20 cases of essential hypertension.
Topics: Adult; Female; Glycine; Humans; Hypertension; Male; Middle Aged; Mutation; Receptors, Glucagon; Serine | 1996 |
Efficient L-serine production from methanol and glycine by resting cells of Methylobacterium sp. strain MN43.
Topics: Cell Cycle; Culture Media; Glycine; Gram-Negative Aerobic Bacteria; Kinetics; Methanol; Serine | 1996 |
A glycine (415)-to-serine substitution results in impaired secretion and decreased thermal stability of type III procollagen in a patient with Ehlers-Danlos syndrome type IV.
Topics: Adult; Ehlers-Danlos Syndrome; Female; Glycine; Hot Temperature; Humans; Procollagen; Serine | 1997 |
Mechanisms of amino acid-induced insulin secretion from the glucose-responsive BRIN-BD11 pancreatic B-cell line.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Calcium Channel Blockers; Cell Line; Diazoxide; Dose-Response Relationship, Drug; Glucose; Glutamine; Glyceraldehyde; Glycine; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Lysine; Potassium Channels; Proline; Radioimmunoassay; Rats; Serine; Stimulation, Chemical; Verapamil | 1996 |
Skeletal development in transgenic mice expressing a mutation at Gly574Ser of type II collagen.
Topics: Animals; Bone Development; Female; Glycine; Male; Mice; Mice, Transgenic; Phenotype; Point Mutation; Serine | 1997 |
D-serine as a neuromodulator: regional and developmental localizations in rat brain glia resemble NMDA receptors.
Topics: Animals; Brain Chemistry; Cerebellum; Glycine; Hippocampus; Ligands; Models, Neurological; Neuroglia; Neurotransmitter Agents; Olfactory Bulb; Organ Specificity; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Rhombencephalon; Serine; Stereoisomerism; Telencephalon | 1997 |
Altered Rous sarcoma virus Gag polyprotein processing and its effects on particle formation.
Topics: Animals; Avian Sarcoma Viruses; Binding Sites; COS Cells; Defective Viruses; Endopeptidases; Gene Products, gag; Glycine; Mutagenesis; Nucleocapsid; Proline; Protein Precursors; Protein Processing, Post-Translational; Proteins; Serine; Valine; Virion; Virus Assembly | 1997 |
Further evidence of no association between Ser9Gly polymorphism of dopamine D3 receptor gene and schizophrenia.
Topics: Alleles; Asian People; Case-Control Studies; Female; Genotype; Glycine; Humans; Male; Middle Aged; Polymorphism, Genetic; Receptors, Dopamine D2; Receptors, Dopamine D3; Schizophrenia; Serine; Taiwan | 1997 |
A Gly145Ser substitution in the transcriptional activator PrfA causes constitutive overexpression of virulence factors in Listeria monocytogenes.
Topics: Amino Acid Sequence; Bacterial Proteins; Bacterial Toxins; Codon; Cyclic AMP; Cyclic AMP Receptor Protein; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Glycine; Heat-Shock Proteins; Hemolysin Proteins; Listeria monocytogenes; Molecular Sequence Data; Mutagenesis, Insertional; Peptide Termination Factors; Phospholipases; Point Mutation; Serine; Temperature; Trans-Activators; Transcription, Genetic; Virulence | 1997 |
Bond-specific chemical cleavages of peptides and proteins with perfluoric acid vapors: novel peptide bond cleavages of glycyl-threonine, the amino side of serine residues and the carboxyl side of aspartic acid residues.
Topics: Amino Acid Sequence; Aspartic Acid; Fluorocarbons; Glycine; Molecular Sequence Data; Peptides; Proline; Proteins; Serine; Threonine | 1997 |
Serine319 and 321 are functional in isocitrate lyase from Escherichia coli.
Topics: Alanine; Asparagine; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression Regulation, Bacterial; Glycine; Histidine; Isocitrate Lyase; Isocitrates; Kinetics; Magnesium; Mutagenesis, Site-Directed; Oligonucleotides; Plasmids; Proline; Sequence Alignment; Serine; Threonine | 1997 |
Depletion of cerebral D-serine in non-ketotic hyperglycinemia: possible involvement of glycine cleavage system in control of endogenous D-serine.
Topics: Amino Acid Oxidoreductases; Animals; Animals, Newborn; Brain; Carrier Proteins; Cerebral Cortex; Cysteamine; Glycine; Multienzyme Complexes; Rats; Serine; Stereoisomerism; Transferases | 1997 |
Amino acid concentrations in hypothalamic and caudate nuclei during microwave-induced thermal stress: analysis by microdialysis.
Topics: Amino Acids; Animals; Aspartic Acid; Body Temperature; Caudate Nucleus; Chromatography, High Pressure Liquid; Electromagnetic Fields; Functional Laterality; Glutamic Acid; Glutamine; Glycine; Hot Temperature; Hypothalamus; Male; Microdialysis; Microwaves; Rats; Rats, Sprague-Dawley; Serine; Skin Temperature; Stress, Physiological; Time Factors | 1997 |
Serine for glycine substitutions in the C-terminal third of the alpha 1(I) chain of collagen I in five patients with nonlethal osteogenesis imperfecta.
Topics: Adolescent; Adult; Cells, Cultured; Child; Collagen; DNA Mutational Analysis; Exons; Fibroblasts; Genes; Glycine; Humans; Infant; Osteogenesis Imperfecta; Peptide Mapping; Phenotype; Point Mutation; Serine; Skin | 1997 |
Partition of transient and sustained inhibitory glycinergic input to retinal ganglion cells.
Topics: Alanine; Ambystoma; Animals; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Glycine Agents; Kynurenic Acid; Receptors, Glycine; Retinal Ganglion Cells; Serine; Strychnine; Synaptic Transmission; Taurine | 1997 |
Temperature dependency of basal and evoked release of amino acids and calcitonin gene-related peptide from rat dorsal spinal cord.
Topics: Animals; Aspartic Acid; Body Temperature; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Chromatography, High Pressure Liquid; Cross Reactions; Fever; Glutamic Acid; Glycine; Hypothermia; Male; Organ Culture Techniques; Potassium; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord; Synaptic Transmission | 1997 |
Dietary protein and amino acid levels alter threonine dehydrogenase activity in hepatic mitochondria of Gallus domesticus.
Topics: Alcohol Oxidoreductases; Amino Acids; Animals; Chickens; Dietary Proteins; Eating; Enzyme Activation; Female; Food Deprivation; Glycine; Liver; Male; Mitochondria, Liver; Serine; Threonine | 1997 |
Microdialysis of human breast tissue during the menstrual cycle.
Topics: Adipose Tissue; Adult; Amino Acids; Asparagine; Aspartic Acid; Breast; Chromatography, High Pressure Liquid; Female; Glycine; Humans; Lactic Acid; Menstrual Cycle; Microdialysis; Ornithine; Pyruvic Acid; Serine; Threonine; Tyrosine | 1997 |
A point mutation of human nucleoside diphosphate kinase A found in aggressive neuroblastoma affects protein folding.
Topics: Antigens, Neoplasm; Chromatography, Gel; Circular Dichroism; Glycine; Humans; Kinetics; Molecular Weight; Monomeric GTP-Binding Proteins; Neuroblastoma; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Point Mutation; Protein Folding; Serine; Transcription Factors | 1997 |
Amino acid sequence environment modulates the disruption by osteogenesis imperfecta glycine substitutions in collagen-like peptides.
Topics: Amino Acid Sequence; Circular Dichroism; Collagen; Glycine; Humans; Molecular Sequence Data; Osteogenesis Imperfecta; Peptide Fragments; Protein Conformation; Protein Folding; Protein Structure, Secondary; Serine | 1997 |
Design of a leucine zipper coiled coil stabilized 1.4 kcal mol-1 by phosphorylation of a serine in the e position.
Topics: Amino Acid Sequence; Arginine; Avian Proteins; Basic-Leucine Zipper Transcription Factors; Carrier Proteins; Centrifugation, Isopycnic; Circular Dichroism; Cyclic AMP-Dependent Protein Kinases; DNA Probes; DNA-Binding Proteins; G-Box Binding Factors; Genes, Reporter; Glutamic Acid; Glycine; Hot Temperature; Leucine Zippers; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoproteins; Phosphorylation; Protein Binding; Protein Denaturation; Protein Engineering; Protein Structure, Secondary; Recombinant Proteins; Serine; Threonine; Transcription Factors; Transcriptional Activation; Transfection | 1997 |
The origin and turnover of D-serine in brain.
Topics: Amino Acid Isomerases; Animals; Brain; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Glucose; Glycine; Mice; Mice, Inbred Strains; Microdialysis; Rats; Rats, Sprague-Dawley; Serine; Stereoisomerism | 1997 |
Role of the glycine triad in the ATP-binding site of cAMP-dependent protein kinase.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Animals; Binding Sites; Cyclic AMP-Dependent Protein Kinases; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Glycine; Kinetics; Mice; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Serine; Stereoisomerism; Temperature | 1997 |
Characterization of 5,7-dichlorokynurenate-insensitive D-[3H]serine binding to synaptosomal fraction isolated from rat brain tissues.
Topics: Animals; Binding Sites; Binding, Competitive; Brain Chemistry; Cations; Cerebellum; Cerebral Cortex; Detergents; Excitatory Amino Acid Antagonists; Glycine; Kidney; Kynurenic Acid; Liver; Male; Octoxynol; Rats; Rats, Wistar; Serine; Subcellular Fractions; Synaptosomes; Tritium | 1997 |
6-L-alanineferrirubin, a ferrichrome-type siderophore from the fungus Aspergillus ochraceous.
Topics: Alanine; Aspergillus ochraceus; Crystallography, X-Ray; Ferric Compounds; Glycine; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Molecular Structure; Peptides, Cyclic; Serine; Siderophores | 1997 |
Lysine deficiency in postweaned calves fed corn and corn gluten meal diets.
Topics: Aging; Analysis of Variance; Animals; Arginine; Caseins; Cattle; Cattle Diseases; Cysteine; Deficiency Diseases; Diet; Glutamine; Glutens; Glycine; Lysine; Male; Methionine; Nitrogen; Rumen; Serine; Threonine; Zea mays | 1997 |
Engineering of porcine pepsin. Alteration of S1 substrate specificity of pepsin to those of fungal aspartic proteinases by site-directed mutagenesis.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Aspartic Acid Endopeptidases; Cattle; Fungal Proteins; Glycine; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Pepsin A; Protein Engineering; Protein Structure, Secondary; Recombinant Proteins; Serine; Substrate Specificity; Swine; Threonine | 1997 |
Photosynthesis and fluorescence quenching, and the mRNA levels of plastidic glutamine synthetase or of mitochondrial serine hydroxymethyltransferase (SHMT) in the leaves of the wild-type and of the SHMT-deficient stm mutant of Arabidopsis thaliana in rela
Topics: Arabidopsis; Carbon Dioxide; Fluorescence; Glutamate-Ammonia Ligase; Glycine; Glycine Hydroxymethyltransferase; Mitochondria; Mutation; Photosynthesis; Plant Leaves; Plastids; RNA, Messenger; RNA, Plant; Serine | 1997 |
Identification of a Gly862 to Ser substitution in the type I collagen gene from a single spermatozoon.
Topics: Collagen; DNA; DNA Primers; Female; Fertilization in Vitro; Genetic Testing; Glycine; Humans; Male; Mosaicism; Osteogenesis Imperfecta; Point Mutation; Polymerase Chain Reaction; Pregnancy; Sequence Analysis, DNA; Serine; Spermatozoa | 1996 |
Serine isotopmer analysis by 13C-NMR defines glycine-serine interconversion in situ in the renal proximal tubule.
Topics: Animals; Gas Chromatography-Mass Spectrometry; Glycine; Glycine Hydroxymethyltransferase; Isotope Labeling; Kidney Tubules, Proximal; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Wistar; Serine; Tetrahydrofolates | 1996 |
Modulation of glycine-serine interconversion by TCA and glycolytic intermediates in normoxic and hypoxic proximal tubules.
Topics: Animals; Cell Hypoxia; Cell Survival; Gas Chromatography-Mass Spectrometry; Gluconeogenesis; Glycine; Glycine Hydroxymethyltransferase; Glycolysis; In Vitro Techniques; Isotope Labeling; Kidney Tubules, Proximal; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Wistar; Serine; Tetrahydrofolates; Trichloroacetic Acid | 1996 |
Use of 13C nuclear magnetic resonance to evaluate metabolic flux through folate one-carbon pools in Saccharomyces cerevisiae.
Topics: Carbon Isotopes; Choline; Folic Acid; Formates; Glycine; Leucovorin; Magnetic Resonance Spectroscopy; Purines; Saccharomyces cerevisiae; Serine | 1997 |
Consequences of seven novel mutations on the expression and structure of keratinocyte transglutaminase.
Topics: Arginine; Binding Sites; Factor XIII; Female; Genes, Recessive; Glycine; Humans; Ichthyosis; Keratinocytes; Male; Models, Molecular; Molecular Sequence Data; Pedigree; Point Mutation; Protein Structure, Tertiary; Sequence Deletion; Serine; Structure-Activity Relationship; Transglutaminases; Valine | 1997 |
Lif, the lysostaphin immunity factor, complements FemB in staphylococcal peptidoglycan interpeptide bridge formation.
Topics: Amino Acids; Bacterial Proteins; Carrier Proteins; Cell Wall; Genetic Complementation Test; Glycine; Hexosyltransferases; Lysostaphin; Methicillin Resistance; Multienzyme Complexes; Muramoylpentapeptide Carboxypeptidase; Mutation; Penicillin-Binding Proteins; Peptidoglycan; Peptidyl Transferases; Serine; Staphylococcus aureus | 1997 |
Use of synthetic antigens improves detection by enzyme-linked immunosorbent assay of antibodies against abortigenic Chlamydia psittaci in ruminants.
Topics: Animals; Antibodies, Bacterial; Antigens, Bacterial; Bacterial Outer Membrane Proteins; Bacterial Proteins; Biotin; Cattle; Chlamydophila psittaci; Complement Fixation Tests; Enzyme-Linked Immunosorbent Assay; Epitopes; Glycine; Lipopolysaccharides; Mice; Peptides; Psittacosis; Rats; Recombinant Proteins; Sensitivity and Specificity; Serine; Sheep; Specific Pathogen-Free Organisms; Streptavidin | 1997 |
In vivo evidence for the link between L- and D-serine metabolism in rat cerebral cortex.
Topics: Amino Acids; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Glycine; Kinetics; Male; Mammals; Rats; Rats, Wistar; Serine; Stereoisomerism; Threonine; Time Factors | 1997 |
Maintenance threonine requirement and efficiency of its use for accretion of whole-body threonine and protein in young chicks.
Topics: Analysis of Variance; Animal Nutritional Physiological Phenomena; Animals; Chickens; Cystine; Energy Intake; Glycine; Male; Nutritional Requirements; Proline; Proteins; Regression Analysis; Serine; Threonine; Weight Gain | 1997 |
Extensible collagen in mussel byssus: a natural block copolymer.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Biopolymers; Bivalvia; Collagen; DNA, Complementary; Elasticity; Elastin; Fibroins; Glycine; Histidine; Molecular Sequence Data; Proline; Protein Conformation; Protein Precursors; Protein Structure, Secondary; Sequence Alignment; Serine | 1997 |
Mutations in the C-terminal domain of Sonic Hedgehog cause holoprosencephaly.
Topics: Alanine; Amino Acid Sequence; Animals; Cell Line, Transformed; DNA Mutational Analysis; Exons; Female; Genes, Dominant; Glutamic Acid; Glycine; Hedgehog Proteins; Holoprosencephaly; Humans; Male; Molecular Sequence Data; Pedigree; Point Mutation; Proteins; Sequence Deletion; Sequence Homology, Amino Acid; Serine; Threonine; Trans-Activators; Valine | 1997 |
Construction and characterization of an OHIO-1 beta-lactamase bearing Met69Ile and Gly238Ser mutations.
Topics: beta-Lactam Resistance; beta-Lactamases; Cephalosporin Resistance; Enzyme Inhibitors; Glycine; Isoleucine; Kinetics; Methionine; Mutagenesis, Site-Directed; Mutation; Phenotype; Serine | 1997 |
Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.
Topics: Alanine; Amino Acid Sequence; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Binding Sites; Cell Line; Electrophysiology; Enflurane; Ethanol; Glycine; Humans; Molecular Sequence Data; Mutagenesis; Propofol; Receptors, GABA-A; Receptors, Glycine; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Tryptophan; Xenopus | 1997 |
Heterozygous lipoprotein lipase deficiency: frequency in the general population, effect on plasma lipid levels, and risk of ischemic heart disease.
Topics: Adult; Aged; Aged, 80 and over; Apolipoprotein A-I; Asparagine; Cholesterol, HDL; Coronary Artery Disease; Female; Gene Frequency; Glutamic Acid; Glycine; Heterozygote; Humans; Isoleucine; Lipids; Lipoprotein Lipase; Male; Middle Aged; Phenotype; Point Mutation; Risk Factors; Serine; Triglycerides | 1997 |
Adult vitelliform macular dystrophy is frequently associated with mutations in the peripherin/RDS gene.
Topics: Aged; Female; Glycine; Humans; Intermediate Filament Proteins; Macular Degeneration; Male; Membrane Glycoproteins; Methionine; Middle Aged; Mutation; Nerve Tissue Proteins; Peripherins; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Serine; Threonine; Tryptophan; Valine | 1997 |
Site-directed mutagenesis of the Actinomadura R39 DD-peptidase.
Topics: Actinomycetales; Alanine; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Carboxypeptidases; Carrier Proteins; Conserved Sequence; Glycine; Hexosyltransferases; Kinetics; Molecular Sequence Data; Muramoylpentapeptide Carboxypeptidase; Mutagenesis, Site-Directed; Penicillin-Binding Proteins; Penicillins; Peptidyl Transferases; Protein Denaturation; Protein Structure, Secondary; Recombinant Proteins; Serine; Serine-Type D-Ala-D-Ala Carboxypeptidase; Substrate Specificity | 1997 |
Structure and function of poly(3-hydroxybutyrate) depolymerase from Alcaligenes faecalis T1.
Topics: Alcaligenes; Asparagine; Aspartic Acid; Carboxylic Ester Hydrolases; Chromosome Inversion; DNA Primers; DNA, Bacterial; Gene Expression; Glycine; Histidine; Plasmids; Point Mutation; Polymerase Chain Reaction; Recombinant Fusion Proteins; Sequence Deletion; Serine; Trypsin | 1997 |
In vitro and in vivo characterisation of a recombinant carboxypeptidase G2::anti-CEA scFv fusion protein.
Topics: Animals; Artificial Gene Fusion; Blotting, Western; Carcinoembryonic Antigen; Chromatography, Affinity; Chromosome Mapping; Cloning, Molecular; Coliphages; Colorectal Neoplasms; Escherichia coli; gamma-Glutamyl Hydrolase; Gene Expression; Gene Library; Glycine; Humans; Lac Operon; Mice; Mice, Nude; Mutagenesis, Site-Directed; Neoplasm Transplantation; Polysaccharide-Lyases; Promoter Regions, Genetic; Recombinant Fusion Proteins; Serine; Transplantation, Heterologous | 1996 |
The role of cysteinyl residues in the activity of bacterial elongation factor Ts, a guanosine nucleotide dissociation protein.
Topics: Amino Acid Substitution; Cloning, Molecular; Cysteine; Escherichia coli; Glycine; Guanosine Diphosphate; Kinetics; Mutagenesis, Site-Directed; Peptide Elongation Factors; Protein Conformation; Recombinant Proteins; Sequence Tagged Sites; Serine | 1997 |
Role of mitochondrial and cytoplasmic serine hydroxymethyltransferase isozymes in de novo purine synthesis in Saccharomyces cerevisiae.
Topics: Carbon Isotopes; Cell Compartmentation; Cytoplasm; Folic Acid; Formates; Glycine; Glycine Hydroxymethyltransferase; Isoenzymes; Mitochondria; Nuclear Magnetic Resonance, Biomolecular; Purines; Saccharomyces cerevisiae; Serine | 1997 |
Influence of family history on frequency of glucagon receptor Gly40Ser mutation in hypertensive subjects.
Topics: Adult; Age of Onset; Female; Gene Frequency; Glycine; Humans; Hypertension; Male; Middle Aged; Nuclear Family; Point Mutation; Receptors, Glucagon; Serine | 1997 |
Serine-294 and threonine-295 in the exofacial loop domain between helices 7 and 8 of glucose transporters (GLUT) are involved in the conformational alterations during the transport process.
Topics: Alanine; Amino Acid Sequence; Animals; Biological Transport; COS Cells; Glucose Transporter Type 4; Glycine; Molecular Sequence Data; Monosaccharide Transport Proteins; Muscle Proteins; Mutagenesis, Site-Directed; Protein Conformation; Sequence Homology, Amino Acid; Serine; Threonine | 1998 |
A search for endogenous amino acids in martian meteorite ALH84001.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Glycine; Mars; Meteoroids; Serine; Stereoisomerism | 1998 |
Novel missense mutation (G601S) of HERG in a Japanese long QT syndrome family.
Topics: Amino Acid Substitution; Cation Transport Proteins; Codon; DNA; DNA Mutational Analysis; DNA-Binding Proteins; DNA, Complementary; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Family Health; Glycine; Humans; Japan; Long QT Syndrome; Mutation, Missense; Point Mutation; Polymorphism, Single-Stranded Conformational; Potassium Channels; Potassium Channels, Voltage-Gated; Serine; Trans-Activators; Transcriptional Regulator ERG | 1998 |
Strychnine-sensitive glycine receptors inducing [3H]-acetylcholine release in rat caudatoputamen: a new site of action of ethanol?
Topics: Acetylcholine; Animals; Central Nervous System Depressants; Chloride Channels; Ethanol; Glutamic Acid; Glycine; Male; Putamen; Rats; Rats, Wistar; Receptors, Glycine; Serine | 1997 |
Metabolism of glycine in primary astroglial cells: synthesis of creatine, serine, and glutathione.
Topics: Animals; Animals, Newborn; Arginine; Astrocytes; Brain; Carbon Isotopes; Cells, Cultured; Creatine; Glutathione; Glycine; Kinetics; Methionine; Nuclear Magnetic Resonance, Biomolecular; Rats; Rats, Wistar; Serine | 1998 |
Production and utilization of amino acids by ovine placenta in vivo.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Biological Transport; Female; Fetus; Gestational Age; Glutamic Acid; Glutamine; Glycine; Maternal-Fetal Exchange; Oxygen Consumption; Placenta; Pregnancy; Regional Blood Flow; Serine; Sheep; Uterus | 1998 |
Cysteine 195 has a critical functional role in catalysis by isocitrate lyase from Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Cysteine; Escherichia coli; Glycine; Isocitrate Lyase; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Sequence Alignment; Sequence Analysis; Sequence Homology, Amino Acid; Serine; Threonine; Valine | 1997 |
Neurotransmitters in cerebrospinal fluid reflect pathological activity.
Topics: Adult; Aged; Asparagine; Aspartic Acid; Blood-Brain Barrier; Central Nervous System Diseases; Female; Glutamic Acid; Glutamine; Glycine; Humans; L-Lactate Dehydrogenase; Male; Middle Aged; Neurotransmitter Agents; Serine; Taurine | 1997 |
Analytical and ultrastructural studies of pellicle on primary teeth.
Topics: Amino Acids; Child; Dental Deposits; Dental Enamel; Dental Pellicle; Dentition, Mixed; Electron Probe Microanalysis; Glycine; Humans; Microscopy, Electron; Proteins; Serine; Tooth; Tooth, Deciduous; Tyrosine | 1997 |
Arylsulfatase from Klebsiella pneumoniae carries a formylglycine generated from a serine.
Topics: Alanine; Amino Acid Sequence; Arylsulfatases; Glycine; Klebsiella pneumoniae; Molecular Sequence Data; Peptide Fragments; Prokaryotic Cells; Protein Processing, Post-Translational; Serine | 1998 |
Peroxisomal D-hydroxyacyl-CoA dehydrogenase deficiency: resolution of the enzyme defect and its molecular basis in bifunctional protein deficiency.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxyacyl CoA Dehydrogenases; Abnormalities, Multiple; Base Sequence; Binding Sites; Brain; Cells, Cultured; DNA Primers; Enoyl-CoA Hydratase; Fatal Outcome; Female; Glycine; Humans; Hydro-Lyases; Infant; Magnetic Resonance Imaging; Male; Microbodies; Multienzyme Complexes; Peroxisomal Multifunctional Protein-2; Point Mutation; Polymerase Chain Reaction; Serine; Skin | 1998 |
Functional characterization of human N-methyl-D-aspartate subtype 1A/2D receptors.
Topics: Animals; Calcium; Cells, Cultured; DNA, Complementary; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Glycine; Humans; Kidney; Kynurenic Acid; Membrane Potentials; Molecular Sequence Data; N-Methylaspartate; Oocytes; Patch-Clamp Techniques; Pipecolic Acids; Piperidines; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Xenopus laevis | 1998 |
The dopamine D3 receptor (DRD3) Ser9Gly polymorphism and schizophrenia: a haplotype relative risk study and association with clozapine response.
Topics: Alleles; Antipsychotic Agents; Child; Clozapine; Female; Genetic Carrier Screening; Genotype; Glycine; Haplotypes; Humans; Male; Nuclear Family; Point Mutation; Polymerase Chain Reaction; Receptors, Dopamine D2; Receptors, Dopamine D3; Risk; Schizophrenia; Serine | 1998 |
Sulfatases, trapping of the sulfated enzyme intermediate by substituting the active site formylglycine.
Topics: Alanine; Alkaline Phosphatase; Binding Sites; Catechols; Cerebroside-Sulfatase; Chondro-4-Sulfatase; Galactose; Glycine; Humans; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Serine; Sulfuric Acid Esters | 1998 |
Glycine and D-serine decrease MK-801-induced hyperactivity in mice.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glycine; Injections, Intraventricular; Male; Mice; Motor Activity; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission | 1997 |
European Multicentre Association Study of Schizophrenia: a study of the DRD2 Ser311Cys and DRD3 Ser9Gly polymorphisms.
Topics: Alleles; Cystine; Gene Frequency; Genotype; Glycine; Humans; Polymorphism, Genetic; Receptors, Dopamine D2; Receptors, Dopamine D3; Schizophrenia; Serine | 1998 |
A Gly --> Ser change causes defective folding in vitro of calcium-binding epidermal growth factor-like domains from factor IX and fibrillin-1.
Topics: Amino Acid Substitution; Epidermal Growth Factor; Factor IX; Fibrillin-1; Fibrillins; Glycine; Humans; Microfilament Proteins; Mutation; Protein Folding; Serine | 1998 |
Factor X Nagoya 1 and Nagoya 2: a CRM- factor X deficiency and a dysfunctional CRM+ factor X deficiency characterized by substitution of Arg306 by Cys and of Gly366 by Ser, respectively.
Topics: Adult; Aged; Alleles; Cysteine; Factor X; Factor X Deficiency; Female; Glycine; Humans; Point Mutation; Serine; Structure-Activity Relationship | 1998 |
Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102.
Topics: Alanine; Alkaline Phosphatase; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Phosphates; Protein Conformation; Serine | 1998 |
A novel metabolic communication between neurons and astrocytes: non-essential amino acid L-serine released from astrocytes is essential for developing hippocampal neurons.
Topics: Animals; Astrocytes; Cell Communication; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Fetus; Glycine; Hippocampus; Neurons; Rats; Serine | 1998 |
A point mutation in Galphao and Galphai1 blocks interaction with regulator of G protein signaling proteins.
Topics: Enzyme Activation; Glycine; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Hydrolysis; Mutagenesis, Site-Directed; Serine; Signal Transduction | 1998 |
Kinetic analyses of mutations in the glycine-rich loop of cAMP-dependent protein kinase.
Topics: Amino Acid Substitution; Animals; Binding Sites; Cyclic AMP-Dependent Protein Kinases; Glycine; Kinetics; Mice; Models, Molecular; Mutagenesis, Site-Directed; Serine; Viscosity | 1998 |
Transport is the primary determinant of glycine content in retinal neurons.
Topics: Animals; Biological Transport; Cats; Cells, Cultured; Chickens; Culture Media; Glycine; Glyoxylates; Immunohistochemistry; Macaca fascicularis; Neurons; Rats; Rats, Wistar; Retina; Serine | 1998 |
Mutations to alter Aspergillus awamori glucoamylase selectivity. II. Mutation of residues 119 and 121.
Topics: Aspergillus; Carbohydrate Conformation; Glucan 1,4-alpha-Glucosidase; Glucose; Glycine; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Polysaccharides; Serine; Structure-Activity Relationship; Substrate Specificity | 1998 |
Emergence of a ganciclovir-resistant human cytomegalovirus strain with a new UL97 mutation in an AIDS patient.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Retinitis; Drug Resistance, Microbial; Ganciclovir; Glycine; Humans; Point Mutation; Serine | 1998 |
Identification and characterization of the major phosphorylation sites of the B-type natriuretic peptide receptor.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Glycine; Guanylate Cyclase; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphorylation; Receptors, Atrial Natriuretic Factor; Serine; Structure-Activity Relationship; Threonine | 1998 |
Interconversion of the ligand arrays in the CD and EF sites of oncomodulin. Influence on Ca2+-binding affinity.
Topics: Amino Acid Substitution; Animals; Aspartic Acid; Binding Sites; Calcium; Calcium-Binding Proteins; Calorimetry, Differential Scanning; Glycine; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Parvalbumins; Protein Binding; Protein Structure, Secondary; Serine | 1998 |
Tyrosine and tryptophan act through the same binding site at the dimer interface of yeast chorismate mutase.
Topics: Allosteric Regulation; Binding Sites; Chorismate Mutase; Codon; Dimerization; Glycine; Models, Chemical; Mutagenesis, Site-Directed; Saccharomyces cerevisiae; Serine; Threonine; Tryptophan; Tyrosine | 1998 |
Mutations in the middle of the transmembrane domain reverse the polarity of transport of the influenza virus hemagglutinin in MDCK epithelial cells.
Topics: Amino Acid Sequence; Animals; Binding Sites; Biological Transport; Cell Line; Dogs; Epithelial Cells; Glycine; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Folding; Serine | 1998 |
Non-repetitive single-chain Fv linkers selected by selectively infective phage (SIP) technology.
Topics: Amino Acid Sequence; Antibody Affinity; Bacteriophages; Base Sequence; Binding Sites, Antibody; Enzyme-Linked Immunosorbent Assay; Fluorescein-5-isothiocyanate; Glycine; Immunoglobulin Fragments; Immunoglobulin Variable Region; Molecular Sequence Data; Mutagenesis; Peptide Library; Polymerase Chain Reaction; Protein Conformation; Protein Denaturation; Protein Engineering; Protein Folding; Recombinant Fusion Proteins; Serine; Solubility; Urea | 1998 |
Expression and initial characterization of a soluble glycine binding domain of the N-methyl-D-aspartate receptor NR1 subunit.
Topics: Animals; Baculoviridae; Binding Sites; Binding, Competitive; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Indoles; Kynurenic Acid; Protein Binding; Protein Conformation; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Serine; Spodoptera | 1998 |
Fibrinogen synthesis is elevated in fasting cancer patients with an acute phase response.
Topics: Acute-Phase Reaction; Adenocarcinoma; Adult; Aged; Amino Acids; C-Reactive Protein; Cachexia; Fasting; Female; Fibrinogen; Glycine; Humans; Kinetics; Male; Middle Aged; Muscle Proteins; Pancreatic Neoplasms; Reference Values; Serine; Tryptophan | 1998 |
Effects of flooding amino acids on incorporation of labeled amino acids into human muscle protein.
Topics: Adult; Amino Acids; Arginine; Carbon Isotopes; Glycine; Humans; Isotope Labeling; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Serine; Threonine; Time Factors | 1998 |
Evidence for coupled electron and proton transfer in the [8Fe-7S] cluster of nitrogenase.
Topics: Amino Acid Substitution; Azotobacter vinelandii; Electron Spin Resonance Spectroscopy; Electron Transport; Glycine; Hydrogen-Ion Concentration; Iron; Macromolecular Substances; Molybdoferredoxin; Nitrogenase; Oxidation-Reduction; Protons; Serine | 1998 |
Beneficial effects of L-serine and glycine in the management of seizures in 3-phosphoglycerate dehydrogenase deficiency.
Topics: Carbohydrate Dehydrogenases; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Glycine; Humans; Infant, Newborn; Intellectual Disability; Male; Microcephaly; Phosphoglycerate Dehydrogenase; Seizures; Serine; Tetrahydrofolates | 1998 |
Deleterious missense mutations and silent polymorphism in the human 17beta-hydroxysteroid dehydrogenase 3 gene (HSD17B3).
Topics: 17-Hydroxysteroid Dehydrogenases; Adolescent; Base Composition; Child; Disorders of Sex Development; DNA; Female; Glycine; Humans; Male; Mutagenesis, Site-Directed; Mutation; Polycystic Ovary Syndrome; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Sequence Analysis, DNA; Serine | 1998 |
Induction of resting microglia in culture medium devoid of glycine and serine.
Topics: Acid Phosphatase; Animals; Cells, Cultured; Coloring Agents; Culture Media; Extracellular Matrix Proteins; Fibronectins; Glycine; Laminin; Macrophage Activation; Microglia; Microscopy, Electron; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxazines; Oxygen Consumption; Rats; Serine; Superoxides; Trypan Blue; Xanthenes | 1998 |
Direct evidence of autosomal recessive inheritance of Arg24 to termination codon in purine nucleoside phosphorylase gene in a family with a severe combined immunodeficiency patient.
Topics: Amino Acid Sequence; Arginine; Base Sequence; Child, Preschool; Chromosome Mapping; Chromosomes, Human, Pair 14; Codon, Terminator; Consanguinity; DNA Primers; Erythrocytes; Exons; Female; Genes, Recessive; Genetic Carrier Screening; Glycine; Histidine; Humans; Male; Nuclear Family; Pedigree; Point Mutation; Polymerase Chain Reaction; Purine-Nucleoside Phosphorylase; Serine; Severe Combined Immunodeficiency | 1998 |
Posttranslational formation of formylglycine in prokaryotic sulfatases by modification of either cysteine or serine.
Topics: Alanine; Arylsulfatases; Bacterial Proteins; Binding Sites; Borohydrides; Cysteine; Glycine; Klebsiella pneumoniae; Mutagenesis, Site-Directed; Peptide Fragments; Prokaryotic Cells; Protein Processing, Post-Translational; Pseudomonas aeruginosa; Recombinant Proteins; Sequence Analysis; Serine; Sulfates; Trypsin | 1998 |
Synthesis and characterization of more potent analogues of hirudin fragment 1-47 containing non-natural amino acids.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Cattle; Circular Dichroism; Glycine; Hirudins; Humans; Molecular Sequence Data; Peptide Fragments; Phenylalanine; Serine; Spectrometry, Fluorescence; Thrombin; Tyrosine; Valine | 1998 |
The crystal structure of human cytosolic serine hydroxymethyltransferase: a target for cancer chemotherapy.
Topics: Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cytosol; Dimerization; DNA Replication; Drug Design; Enzyme Inhibitors; Glycine; Glycine Hydroxymethyltransferase; Humans; Models, Chemical; Models, Molecular; Molecular Sequence Data; Neoplasms; Protein Conformation; Protein Folding; Recombinant Proteins; Serine; Tetrahydrofolates | 1998 |
Evidence for functional native NMDA receptors activated by glycine or D-serine alone in the absence of glutamatergic coagonist.
Topics: Animals; Cerebral Cortex; Cholecystokinin; Dose-Response Relationship, Drug; Drug Synergism; Glutamic Acid; Glycine; Male; N-Methylaspartate; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Somatostatin; Stereoisomerism; Synaptosomes | 1998 |
A mutant yeast topoisomerase II (top2G437S) with differential sensitivity to anticancer drugs in the presence and absence of ATP.
Topics: Adenosine Triphosphate; Antineoplastic Agents; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Enzyme Stability; Glycine; Mutagenesis; Saccharomyces cerevisiae; Serine | 1998 |
Two substrate interaction sites in lignin peroxidase revealed by site-directed mutagenesis.
Topics: Basidiomycota; Enzyme Stability; Glutamic Acid; Glycine; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Oxidation-Reduction; Peroxidases; Phenylalanine; Protein Folding; Recombinant Proteins; Serine; Spectrophotometry; Substrate Specificity; Tryptophan | 1998 |
Astrocytes modulate nitric oxide production by microglial cells through secretion of serine and glycine.
Topics: Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Culture Media, Conditioned; Culture Techniques; Glycine; Immunohistochemistry; Microglia; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Serine | 1998 |
Nuclear magnetic resonance shows asymmetric loss of triple helix in peptides modeling a collagen mutation in brittle bone disease.
Topics: Amino Acid Sequence; Amino Acid Substitution; Collagen; Glycine; Humans; Models, Molecular; Molecular Sequence Data; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Osteogenesis Imperfecta; Peptide Fragments; Point Mutation; Protein Conformation; Protein Folding; Protein Structure, Secondary; Serine | 1998 |
Attenuated neurotransmitter release and spreading depression-like depolarizations after focal ischemia in mutant mice with disrupted type I nitric oxide synthase gene.
Topics: Alanine; Animals; Brain; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Cortical Spreading Depression; Ethanolamines; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Laser-Doppler Flowmetry; Male; Membrane Potentials; Mice; Mice, Knockout; Microdialysis; Nerve Tissue Proteins; Neurotoxins; Neurotransmitter Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Serine; Taurine | 1998 |
D-serine and the therapeutic challenge posed by the N-methyl-D-aspartate antagonist model of schizophrenia.
Topics: Glycine; Humans; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine | 1998 |
Detection of more than 91% cystic fibrosis mutations in a sample of the population from Reunion Island and identification of two novel mutations (A309G, S1255L) and one novel polymorphism (L49L)
Topics: Alanine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; France; Glycine; Humans; Leucine; Mutation, Missense; Polymorphism, Genetic; Serine | 1998 |
Functional similarities between the Listeria monocytogenes virulence regulator PrfA and cyclic AMP receptor protein: the PrfA* (Gly145Ser) mutation increases binding affinity for target DNA.
Topics: Bacterial Proteins; Binding Sites; Cyclic AMP Receptor Protein; DNA; Glycine; Listeria monocytogenes; Oligodeoxyribonucleotides; Peptide Termination Factors; Point Mutation; Serine; Trans-Activators; Virulence | 1998 |
Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses.
Topics: Animals; Animals, Newborn; Brain Stem; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Hypoglossal Nerve; In Vitro Techniques; Motor Neurons; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Synapses | 1998 |
One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels.
Topics: Amino Acid Metabolism, Inborn Errors; Benzoic Acid; Brain Diseases; Choline; Coma; Female; Glycine; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methionine; Methylation; Phosphatidylcholines; S-Adenosylmethionine; Seizures; Serine; Tetrahydrofolates | 1998 |
Neurons induce the activation of microglial cells in vitro.
Topics: Animals; Animals, Newborn; Anions; Astrocytes; Carcinogens; Cell Communication; Cell Culture Techniques; Cell Size; Cells, Cultured; Cerebral Cortex; Culture Media, Conditioned; Glycine; Microglia; Microscopy, Electron; N-Acetylneuraminic Acid; Neuraminidase; Neurons; Rats; Serine; Superoxides; Tetradecanoylphorbol Acetate; Trypsin | 1998 |
Context-dependent immunogenicity of an S206G-substituted H-2Db-restricted simian virus 40 large T antigen epitope I variant.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Antigen Presentation; Antigens, Viral, Tumor; Clone Cells; Epitopes, T-Lymphocyte; Genetic Variation; Glycine; H-2 Antigens; Histocompatibility Antigen H-2D; Male; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Serine; Simian virus 40; T-Lymphocytes | 1999 |
The first gene in the biosynthesis of the polyketide antibiotic TA of Myxococcus xanthus codes for a unique PKS module coupled to a peptide synthetase.
Topics: Acetates; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Cloning, Molecular; DNA, Bacterial; Genes, Bacterial; Glycine; Macrolides; Molecular Sequence Data; Multienzyme Complexes; Multigene Family; Mutagenesis, Site-Directed; Myxococcales; Open Reading Frames; Peptide Synthases; Sequence Alignment; Sequence Homology, Amino Acid; Serine | 1999 |
Two serine residues of the glutamate transporter GLT-1 are crucial for coupling the fluxes of sodium and the neurotransmitter.
Topics: Amino Acid Substitution; Amino Acid Transport System X-AG; Aspartic Acid; ATP-Binding Cassette Transporters; Binding Sites; Biological Transport; Glutamic Acid; Glycine; HeLa Cells; Humans; Kainic Acid; Kinetics; Mutagenesis, Site-Directed; Neurotransmitter Agents; Recombinant Proteins; Serine; Sodium | 1999 |
Corticotropin releasing factor (CRF) agonists with reduced amide bonds and Ser7 substitutions.
Topics: Adrenocorticotropic Hormone; Amino Acid Sequence; Animals; Cells, Cultured; Corticotropin-Releasing Hormone; Glycine; Humans; Male; Methylation; Molecular Sequence Data; Oxidation-Reduction; Peptides; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Serine | 1999 |
Crystallization and preliminary X-ray analysis of a new L-aminopeptidase-D-amidase/D-esterase activated by a Gly-Ser peptide bond hydrolysis.
Topics: Aminopeptidases; Bacterial Proteins; Crystallization; Crystallography, X-Ray; Glycine; Hydrolysis; Serine | 1999 |
Missense mutation Gly574Ser in the transcription factor HNF-1alpha is a marker of atypical diabetes mellitus in African-American children.
Topics: Adult; Amino Acid Substitution; Black People; Child; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Genetic Markers; Glycine; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Mutation, Missense; Nuclear Proteins; Polymorphism, Genetic; Senegal; Serine; Transcription Factors; United States | 1999 |
RAGE Gly82Ser polymorphism in diabetic microangiopathy.
Topics: Amino Acid Substitution; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Gene Frequency; Genotype; Glycation End Products, Advanced; Glycine; Humans; Microcirculation; Polymorphism, Genetic; Serine | 1999 |
Raman markers of nonaromatic side chains in an alpha-helix assembly: Ala, Asp, Glu, Gly, Ile, Leu, Lys, Ser, and Val residues of phage fd subunits.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Deuterium; DNA, Single-Stranded; Glutamic Acid; Glycine; Inovirus; Isoleucine; Lysine; Molecular Sequence Data; Protein Structure, Secondary; Serine; Spectrum Analysis, Raman; Valine; Viral Proteins; Virus Assembly | 1999 |
MHC-restricted, glycopeptide-specific T cells show specificity for both carbohydrate and peptide residues.
Topics: Amino Acids; Animals; Binding Sites; CD4-Positive T-Lymphocytes; Disaccharides; Epitopes, T-Lymphocyte; Glycine; Glycopeptides; Histocompatibility Antigens Class II; Hybridomas; Mice; Mice, Inbred CBA; Muramidase; Peptide Fragments; Receptors, Antigen, T-Cell; Serine | 1999 |
[3H]CGP 61594, the first photoaffinity ligand for the glycine site of NMDA receptors.
Topics: Affinity Labels; Animals; Azides; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Cerebral Cortex; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Agonists; Glycine; Hippocampus; In Vitro Techniques; Kinetics; Ligands; Male; N-Methylaspartate; Neocortex; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Tritium | 1999 |
The iron sulfur protein AtsB is required for posttranslational formation of formylglycine in the Klebsiella sulfatase.
Topics: Alanine; Bacterial Proteins; Borohydrides; Cloning, Molecular; Escherichia coli; Gene Expression Regulation, Bacterial; Glycine; Iron-Sulfur Proteins; Klebsiella pneumoniae; Molecular Sequence Data; Protein Processing, Post-Translational; Recombinant Proteins; Serine; Sulfatases; Transfection | 1999 |
Prognostic significance of transcription factor E2F-1 in bladder cancer: genotypic and phenotypic characterization.
Topics: Carcinoma; Carrier Proteins; Cell Cycle Proteins; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; Genotype; Glycine; Humans; Immunohistochemistry; Lymphatic Metastasis; Multivariate Analysis; Mutation; Neoplasm Invasiveness; Neoplasm Staging; Phenotype; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Prognosis; Retinoblastoma-Binding Protein 1; Serine; Transcription Factor DP1; Transcription Factors; Urinary Bladder Neoplasms | 1999 |
An extra tRNAGly(U*CU) found in ascidian mitochondria responsible for decoding non-universal codons AGA/AGG as glycine.
Topics: Animals; Base Sequence; Codon; Glycine; Mitochondria; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Transfer, Gly; RNA, Transfer, Ser; Serine; Urochordata | 1999 |
Ligand binding by antibody IgE Lb4: assessment of binding site preferences using microcalorimetry, docking, and free energy simulations.
Topics: Animals; Binding Sites; Biophysical Phenomena; Biophysics; Calorimetry; Cross Reactions; Dinitrobenzenes; Glycine; Immunoglobulin E; In Vitro Techniques; Ligands; Models, Molecular; Phenylalanine; Protein Conformation; Serine; Thermodynamics | 1999 |
McArdle's disease associated with homozygosity for the missense mutation Gly204Ser of the myophosphorylase gene in a Spanish patient.
Topics: Adult; Amino Acid Substitution; DNA; DNA Mutational Analysis; Glycine; Glycogen Storage Disease Type V; Homozygote; Humans; Male; Mutation, Missense; Phosphorylases; Serine; Spain | 1999 |
Genotypic association between the dopamine D3 receptor and tardive dyskinesia in chronic schizophrenia.
Topics: Adult; Antipsychotic Agents; Dyskinesia, Drug-Induced; Female; Genotype; Glycine; Humans; Israel; Jews; Male; Middle Aged; Receptors, Dopamine D2; Receptors, Dopamine D3; Reference Values; Schizophrenia; Serine | 1999 |
Atypical processing of amyloid precursor fusion protein by proteolytic activity in Pichia pastoris.
Topics: Amino Acid Sequence; Amyloid beta-Protein Precursor; Antibodies; Blotting, Western; Culture Media, Conditioned; Dimerization; Epitopes; Glycine; Glycosylation; Horseradish Peroxidase; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Pichia; Protein Processing, Post-Translational; Protein Sorting Signals; Recombinant Fusion Proteins; Sequence Analysis; Serine | 1999 |
The speed limit for protein folding measured by triplet-triplet energy transfer.
Topics: Energy Transfer; Glycine; Models, Chemical; Peptides; Protein Folding; Serine; Spectrophotometry, Atomic; Time Factors; Viscosity | 1999 |
Mutations of human topoisomerase II alpha affecting multidrug resistance and sensitivity.
Topics: Adenosine Triphosphate; Antigens, Neoplasm; Antineoplastic Agents; Arginine; Catalysis; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Activation; Glutamic Acid; Glutamine; Glycine; Humans; Isoenzymes; Mutagenesis, Site-Directed; Proline; Serine; Teniposide; Tumor Cells, Cultured | 1999 |
Rapid uptake and degradation of glycine by astroglial cells in culture: synthesis and release of serine and lactate.
Topics: Animals; Animals, Newborn; Astrocytes; Biological Transport; Carbon Isotopes; Carbon Radioisotopes; Cells, Cultured; Chromatography, High Pressure Liquid; Glycine; Kinetics; Lactates; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Rats; Rats, Wistar; Serine | 1999 |
Hydrogen bonding modulates binding of exogenous ligands in a myoglobin proximal cavity mutant.
Topics: Alanine; Amino Acid Substitution; Animals; Binding Sites; Glycine; Histidine; Hydrogen Bonding; Imidazoles; Ligands; Macromolecular Substances; Metmyoglobin; Models, Chemical; Mutagenesis, Insertional; Myoglobin; Nitric Oxide; Nuclear Magnetic Resonance, Biomolecular; Protons; Serine; Threonine; Whales | 1999 |
The inwardly rectifying K(+) channel subunit GIRK1 rescues the GIRK2 weaver phenotype.
Topics: Amino Acid Substitution; Animals; Brain; Carbachol; Dimerization; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Glycine; GTP-Binding Proteins; Membrane Potentials; Mice; Mice, Neurologic Mutants; Oocytes; Phenotype; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Recombinant Proteins; Serine; Xenopus laevis | 1999 |
Analysis of the Gly40Ser polymorphism in the glucagon receptor gene in a German non-insulin-dependent diabetes mellitus population.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Europe; Gene Frequency; Germany; Glycine; Humans; Japan; Middle Aged; Mutation, Missense; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Receptors, Glucagon; Serine | 1999 |
Localization of L-glutamate and glutamate-like receptors at the squid giant synapse.
Topics: Alanine; Animals; Antibody Specificity; Aspartic Acid; Blotting, Western; Chromatography, High Pressure Liquid; Decapodiformes; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Glutamic Acid; Glycine; Receptors, Glutamate; Serine; Synapses; Taurine | 1999 |
Role of formaldehyde in direct formation of glycine and serine in bean leaves.
Topics: Fabaceae; Formaldehyde; Glycine; Hydrogen-Ion Concentration; Photosynthesis; Plant Leaves; Plants, Medicinal; Serine | 1998 |
Catalytic mechanism of the tryptophan synthase alpha(2)beta(2) complex. Effects of pH, isotopic substitution, and allosteric ligands.
Topics: Alanine; Allosteric Regulation; Catalytic Domain; Deuterium; Glycine; Hydrogen-Ion Concentration; Indoles; Ligands; Models, Chemical; Oxindoles; Pyridoxal Phosphate; Salmonella typhimurium; Serine; Tryptophan Synthase | 1999 |
Induction, characterisation and pathogenicity in rainbow trout Oncorhynchus mykiss (Walbaum) of Lactococcus garvieae L-forms.
Topics: Animals; Antibodies, Bacterial; Cell Culture Techniques; Cell Wall; Charcoal; Electrophoresis, Polyacrylamide Gel; Erythromycin; Fish Diseases; Fluorescent Antibody Technique, Indirect; Glycine; Gram-Positive Bacterial Infections; Lactococcus; Lysine; Microscopy, Electron; Oncorhynchus mykiss; Phenylalanine; Rabbits; Serine; Threonine | 1999 |
Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases.
Topics: Acetophenones; Alanine; Amino Acids; Animals; Arachidonic Acids; Aspartic Acid; Brain Edema; Cerebral Cortex; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dimethyl Sulfoxide; Enzyme Inhibitors; Estrenes; Ethanolamines; Fatty Acids, Unsaturated; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hypotonic Solutions; Male; Osmotic Pressure; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Protein Kinase C; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Serine; Solvents; Taurine; Water-Electrolyte Balance | 1999 |
Reduction of ultraviolet light-induced oxidative stress by amino acid-based iron chelators.
Topics: Animals; Antioxidants; Cell Survival; Electron Spin Resonance Spectroscopy; Ferric Compounds; Fibroblasts; Glycine; Hydroxyl Radical; In Vitro Techniques; Iron Chelating Agents; Lipid Peroxidation; Mice; Oxidative Stress; Phenols; Serine; Skin; Spectrophotometry, Ultraviolet; Ultraviolet Rays | 1999 |
Hyperglycemia enhances extracellular glutamate accumulation in rats subjected to forebrain ischemia.
Topics: Alanine; Animals; Brain Ischemia; Glutamic Acid; Glutamine; Glycine; Hyperglycemia; Male; Prosencephalon; Rats; Rats, Wistar; Serine; Taurine | 2000 |
The utilization of alanine, glutamic acid, and serine as amino acid substrates for glycine N-acyltransferase.
Topics: Acyltransferases; Alanine; Animals; Cattle; Glutamic Acid; Glycine; Humans; Kinetics; Serine | 2000 |
Effects of glyphosate and dalapon on total free amino acid profiles of Pseudosuccinea columella snails.
Topics: Alanine; Amino Acids; Animals; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Glyphosate; Herbicides; Propionates; Serine; Snails; Threonine | 2000 |
A new nonamyloid transthyretin variant, G101S, detected by electrospray ionization/mass spectrometry. Mutations in brief no. 201. Online.
Topics: Aged; Amyloid Neuropathies; Glycine; Humans; Male; Mass Spectrometry; Point Mutation; Prealbumin; Protein Isoforms; Serine | 1998 |
Serine and glycine transport in fetal ovine hepatocytes.
Topics: Animals; Binding, Competitive; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Embryonic and Fetal Development; Fetus; Gestational Age; Glucose; Glycine; Kinetics; Leucine; Liver; Serine; Sheep | 2000 |
Developmental expression of a tandemly repeated, glycine- and serine-rich spore wall protein in the microsporidian pathogen Encephalitozoon cuniculi.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibodies, Protozoan; Antigens, Protozoan; Cloning, Molecular; Encephalitozoon cuniculi; Fluorescent Antibody Technique, Indirect; Fungal Proteins; Gene Expression Regulation, Developmental; Glycine; Glycosaminoglycans; Hybridomas; Kinetics; Mice; Mice, Inbred BALB C; Microscopy, Immunoelectron; Molecular Sequence Data; Protozoan Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Spores; Time Factors | 2000 |
An engineered blockage within the ammonia tunnel of carbamoyl phosphate synthetase prevents the use of glutamine as a substrate but not ammonia.
Topics: Alanine; Ammonia; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carbamyl Phosphate; Escherichia coli; Glutamic Acid; Glutamine; Glycine; Kinetics; Lysine; Methionine; Mutagenesis, Site-Directed; Phenylalanine; Serine; Substrate Specificity; Time Factors | 2000 |
Enzyme I of the phosphoenolpyruvate:sugar phosphotransferase system. In vitro intragenic complementation: the roles of Arg126 in phosphoryl transfer and the C-terminal domain in dimerization.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Cysteine; Dimerization; Enzyme Activation; Genes, Bacterial; Genetic Complementation Test; Glycine; Kinetics; Molecular Sequence Data; Peptide Fragments; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphorylation; Phosphotransferases (Nitrogenous Group Acceptor); Point Mutation; Protein Structure, Tertiary; Salmonella typhimurium; Serine; Temperature | 2000 |
Structure and stability effects of the mutation of glycine 34 to serine in Rhodobacter capsulatus cytochrome c(2).
Topics: Amino Acid Substitution; Cytochrome c Group; Cytochromes c2; Enzyme Stability; Glycine; Point Mutation; Rhodobacter capsulatus; Serine; Structure-Activity Relationship | 2000 |
D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor.
Topics: Aging; Animals; Astrocytes; Cells, Cultured; Cerebellum; D-Amino-Acid Oxidase; Embryo, Mammalian; Glycine; Hippocampus; In Vitro Techniques; Ligands; Male; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism | 2000 |
Effect of IGF-I on serine metabolism in fetal sheep.
Topics: Animals; Fetus; Glycine; Hindlimb; Infusions, Intravenous; Insulin-Like Growth Factor I; Oxidation-Reduction; Placenta; Serine; Sheep | 2000 |
Arginine kinase from Nautilus pompilius, a living fossil. Site-directed mutagenesis studies on the role of amino acid residues in the Guanidino specificity region.
Topics: Amino Acid Sequence; Animals; Arginine Kinase; Base Sequence; Catalytic Domain; Decapodiformes; Evolution, Molecular; Glycine; Horseshoe Crabs; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Mollusca; Mutagenesis, Site-Directed; Octopodiformes; Phylogeny; Sequence Homology, Amino Acid; Serine; Tyrosine; Valine | 2000 |
Additive effects of a two-amino-acid insertion and a single-amino-acid substitution in dihydropteroate synthase for the development of sulphonamide-resistant Neisseria meningitidis.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Dihydropteroate Synthase; DNA Transposable Elements; Drug Resistance, Microbial; Escherichia coli; Genes, Bacterial; Glycine; Humans; Mutagenesis, Site-Directed; Neisseria meningitidis; Serine; Sulfonamides; Transformation, Bacterial | 2000 |
Characterization of beta-galactosidase mutations Asp332-->Asn and Arg148-->Ser, and a polymorphism, Ser532-->Gly, in a case of GM1 gangliosidosis.
Topics: Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Base Sequence; beta-Galactosidase; CHO Cells; COS Cells; Cricetinae; DNA Primers; Fluorescent Antibody Technique; Gangliosidosis, GM1; Glycine; Humans; Mutation, Missense; Serine | 2000 |
Gly82Ser polymorphism of the receptor of advanced glycation end product gene is not associated with coronary heart disease in Finnish nondiabetic subjects or in patients with type 2 diabetes.
Topics: Amino Acid Substitution; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Finland; Glycine; Humans; Male; Middle Aged; Polymorphism, Genetic; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reference Values; Serine | 2000 |
Ornithine-containing lipids stimulate CD14-dependent TNF-alpha production from murine macrophage-like J774.1 and RAW 264.7 cells.
Topics: Animals; Binding, Competitive; Cell Line; Culture Media; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glycine; In Situ Hybridization; Interleukin-1; Lipids; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophages; Mice; Ornithine; Prostaglandins; RNA, Messenger; Serine; Signal Transduction; Tumor Necrosis Factor-alpha | 2000 |
Modulation of chemotaxis, O(2)(-) production and myeloperoxidase release from human polymorphonuclear leukocytes by the ornithine-containing lipid and the serineglycine-containing lipid of Flavobacterium.
Topics: Cells, Cultured; Chemotaxis; Dose-Response Relationship, Drug; Flavobacterium; Glycine; Humans; Lipids; Neutrophils; Ornithine; Peroxidase; Serine; Superoxides | 2000 |
Regulation of the balance of one-carbon metabolism in Saccharomyces cerevisiae.
Topics: Adenine; Amino Acid Oxidoreductases; Aminohydrolases; Aminomethyltransferase; Animals; beta-Galactosidase; Carbon; Carrier Proteins; Choline; Cytoplasm; Dose-Response Relationship, Drug; Formate-Tetrahydrofolate Ligase; Fungal Proteins; Gene Expression Regulation, Fungal; Glycine; Glycine Decarboxylase Complex; Glycine Dehydrogenase (Decarboxylating); Glycine Hydroxymethyltransferase; Kinetics; Magnetic Resonance Spectroscopy; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Knockout; Mitochondria; Mitochondrial Proteins; Models, Biological; Multienzyme Complexes; Plasmids; Protein Binding; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Signal Transduction; Tetrahydrofolates; Transcription, Genetic; Transferases; Up-Regulation | 2000 |
Density-functional study of vanadate-glycylserine isomers.
Topics: Dipeptides; Glycine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Serine; Stereoisomerism; Vanadium Compounds | 2000 |
Serine-53 at the tip of the glycine-rich loop of cAMP-dependent protein kinase: role in catalysis, P-site specificity, and interaction with inhibitors.
Topics: Animals; Binding, Competitive; Carrier Proteins; Catalysis; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Cyclic AMP-Dependent Protein Kinase RIIalpha Subunit; Cyclic AMP-Dependent Protein Kinases; Escherichia coli; Glycine; Intracellular Signaling Peptides and Proteins; Kinetics; Mice; Mutagenesis, Site-Directed; Peptides; Serine; Substrate Specificity; Viscosity | 2000 |
cAMP-dependent protein kinase inhibits mGluR2 coupling to G-proteins by direct receptor phosphorylation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Amino Acid Sequence; Animals; Anticonvulsants; CHO Cells; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclopropanes; Dentate Gyrus; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoquinolines; Molecular Sequence Data; Mutagenesis; Neurons; Perforant Pathway; Phosphorylation; Protein Binding; Rats; Receptors, Metabotropic Glutamate; Serine; Sulfonamides; Transfection | 2000 |
Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8.
Topics: Alanine; Apoptosis; Binding Sites; Caspase 1; Caspase 3; Caspase 6; Caspase 7; Caspase 8; Caspase 9; Caspases; Catalysis; Escherichia coli; Fluorescent Dyes; Glycine; Humans; Kinetics; Models, Molecular; ortho-Aminobenzoates; Peptides; Protein Binding; Proteins; Recombinant Proteins; Serine; Substrate Specificity; Tyrosine | 2000 |
Characterization of cucurbita maxima phloem serpin-1 (CmPS-1). A developmentally regulated elastase inhibitor.
Topics: Amino Acid Sequence; Animals; Aphids; Binding Sites; Blotting, Western; Chymotrypsin; Cloning, Molecular; Cucurbitaceae; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Glycine; Kinetics; Molecular Sequence Data; Polymerase Chain Reaction; Protein Binding; Recombinant Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serine; Serine Proteinase Inhibitors; Serpins; Thrombin; Time Factors; Trypsin; Valine | 2000 |
S20G mutation of the amylin gene in Japanese patients with type 2 diabetes.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Amyloid; Asian People; Blood Glucose; Diabetes Mellitus, Type 2; Female; Genetic Carrier Screening; Glycine; Humans; Islet Amyloid Polypeptide; Japan; Male; Middle Aged; Mutation, Missense; Reference Values; Serine | 2000 |
L-serine and glycine serve as major astroglia-derived trophic factors for cerebellar Purkinje neurons.
Topics: Animals; Carbohydrate Dehydrogenases; Cells, Cultured; Excitatory Amino Acids; Glycine; Immunohistochemistry; In Situ Hybridization; Membrane Potentials; Microscopy, Electron; Phosphoglycerate Dehydrogenase; Purkinje Cells; Rats; Rats, Wistar; RNA, Messenger; Serine | 2000 |
(R)-tert-Butoxycarbonylamino-fluorenylmethoxycarbonyl-glycine from (S)-benzyloxycarbonyl-serine or from papain resolution of the corresponding amide or methyl ester.
Topics: Amides; Esters; Glycine; Hydrolysis; Papain; Serine; Stereoisomerism | 2000 |
Application of a metal switch to aqualysin I, a subtilisin-type bacterial serine protease, to the S3 site residues, ser102 and gly131.
Topics: Amino Acid Substitution; Catalysis; Cations, Divalent; Copper; Glycine; Histidine; Kinetics; Mutagenesis, Site-Directed; Nickel; Recombinant Proteins; Serine; Serine Endopeptidases; Substrate Specificity; Thermus; Zinc | 2000 |
Identification of a polymorphism (G83S) in the TWIST gene in Taiwanese.
Topics: Amino Acid Substitution; Asian People; Craniosynostoses; Glycine; Helix-Loop-Helix Motifs; Humans; Male; Nuclear Proteins; Polymorphism, Genetic; Serine; Taiwan; Transcription Factors; Twist-Related Protein 1 | 2000 |
Improvement of the viability of cultured rat neurons by the non-essential amino acids L-serine and glycine that upregulates expression of the anti-apoptotic gene product Bcl-w.
Topics: Animals; Apoptosis; bcl-X Protein; Cell Survival; Cells, Cultured; Cerebral Cortex; Coloring Agents; Fetus; Gene Expression Regulation; Glycine; Microtubule-Associated Proteins; Nerve Degeneration; Neurons; Oxazines; Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Serine; Up-Regulation; Xanthenes | 2000 |
Defining the steps of the folate one-carbon shuffle and homocysteine metabolism.
Topics: Folic Acid; Glycine; Homocysteine; Humans; Methionine; Methylation; Serine | 2000 |
Constitutively activating TSH-receptor mutations as a molecular cause of non-autoimmune hyperthyroidism in childhood.
Topics: Child; Child, Preschool; Exons; Germ-Line Mutation; Glycine; Humans; Hyperthyroidism; Infant; Receptors, Thyrotropin; Serine | 2000 |
Identification of genetic variants (g789C>T and G111S) in the human HSPB2 gene.
Topics: Amino Acid Substitution; Cardiomyopathies; Crystallins; Cytosine; Glycine; Heat-Shock Proteins; Humans; Mutation, Missense; Polymorphism, Genetic; Serine; Thymine | 2001 |
N-methyl-D-aspartate receptors mediating hippocampal noradrenaline and striatal dopamine release display differential sensitivity to quinolinic acid, the HIV-1 envelope protein gp120, external pH and protein kinase C inhibition.
Topics: Animals; Aspartic Acid; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; HIV Envelope Protein gp120; Hydrogen-Ion Concentration; Male; N-Methylaspartate; Norepinephrine; Piperidines; Protein Kinase C; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synaptosomes; Zinc | 2001 |
Identification of residues in the carboxy-terminal domain of Clostridium perfringens alpha-toxin (phospholipase C) which are required for its biological activities.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Toxins; Calcium-Binding Proteins; Clostridium perfringens; DNA, Bacterial; Egg Yolk; Glutamic Acid; Glycine; Hemolysis; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Phospholipids; Phosphorylcholine; Protein Conformation; Serine; Substrate Specificity; Type C Phospholipases | 2000 |
The role of a proline-induced broken-helix motif in alpha-helix 2 of Bacillus thuringiensis delta-endotoxins.
Topics: Alanine; Amino Acid Motifs; Animals; Bacillus thuringiensis; Bacillus thuringiensis Toxins; Bacterial Proteins; Bacterial Toxins; Cell Membrane; Chromatography, High Pressure Liquid; Electrophysiology; Endotoxins; Glycine; Hemolysin Proteins; Manduca; Microvilli; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Proline; Protein Structure, Secondary; Serine; Temperature; Time Factors | 2001 |
An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Biological Clocks; Casein Kinases; Chromosome Mapping; Chromosomes, Human, Pair 2; Circadian Rhythm; Exons; Female; Genetic Linkage; Glycine; Humans; Male; Molecular Sequence Data; Mutation, Missense; Nuclear Proteins; Pedigree; Period Circadian Proteins; Phosphorylation; Polymorphism, Single-Stranded Conformational; Protein Kinases; Proteins; Serine; Sleep Disorders, Circadian Rhythm; Transcription Factors | 2001 |
A G1127S change in calcium-binding epidermal growth factor-like domain 13 of human fibrillin-1 causes short range conformational effects.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Calcium; Cloning, Molecular; Conserved Sequence; Epidermal Growth Factor; Extracellular Matrix Proteins; Fibrillin-1; Fibrillins; Genetic Variation; Glycine; Humans; Marfan Syndrome; Microfilament Proteins; Models, Molecular; Molecular Sequence Data; Mutation, Missense; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Serine | 2001 |
Inactivation of pyruvate formate-lyase by dioxygen: defining the mechanistic interplay of glycine 734 and cysteine 419 by rapid freeze-quench EPR.
Topics: Acetylation; Acetyltransferases; Alanine; Cysteine; Electron Spin Resonance Spectroscopy; Enzyme Activation; Escherichia coli; Free Radicals; Freezing; Glycine; Mutagenesis, Site-Directed; Oxygen; Peroxides; Serine | 2001 |
Effect of the glycine modulatory site of the N-methyl-D-aspartate receptor on synaptic responses in kitten visual cortex.
Topics: Animals; Binding Sites; Cats; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Glycine; Kynurenic Acid; Long-Term Potentiation; Male; Membrane Potentials; Neurons; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Synaptic Transmission; Visual Cortex | 2001 |
Syntheses of glycine and L-serine by their interconversion in the posterior silkgland of the silkworm, Bombyx mori.
Topics: Animals; Bombyx; Carbon Isotopes; Fibroins; Formates; Glycine; Isotope Labeling; Magnetic Resonance Spectroscopy; Organ Culture Techniques; Serine; Tetrahydrofolates | 2001 |
Metabolic response of potato plants to an antisense reduction of the P-protein of glycine decarboxylase.
Topics: Amino Acid Oxidoreductases; Amino Acids; Antisense Elements (Genetics); Carbon Dioxide; Chlorophyll; Chromosome Mapping; Glycine; Glycine Dehydrogenase (Decarboxylating); Light; Mitochondria; Oxygen Consumption; Phenotype; Photosynthesis; Plant Leaves; Plants, Genetically Modified; Serine; Solanum tuberosum | 2001 |
Peptide bond formation mediated by 4,5-dimethoxy-2-mercaptobenzylamine after periodate oxidation of the N-terminal serine residue.
Topics: Amino Acid Sequence; Benzylamines; Chromatography, High Pressure Liquid; Glycine; Molecular Structure; Oxidation-Reduction; Peptides; Sequence Analysis, Protein; Serine; Structure-Activity Relationship; Sulfhydryl Compounds; Threonine | 2001 |
Electrically induced release of labelled taurine, alpha- and beta-alanine, glycine, glutamate and other amino acids from rat neocortical slices in vitro.
Topics: Alanine; Animals; Aspartic Acid; Carnosine; Electric Stimulation; Glutamic Acid; Glycine; Histidine; Neocortex; Neurons; Organ Culture Techniques; Rats; Serine; Taurine; Tritium | 1976 |
Structural similarity of ghrelin derivatives to peptidyl growth hormone secretagogues.
Topics: Amino Acid Sequence; Animals; Calcium; CHO Cells; Cricetinae; Ghrelin; Glycine; Hormones; Humans; Oligopeptides; Peptide Hormones; Peptides; Phenylalanine; Rats; Serine; Structure-Activity Relationship | 2001 |
[Study of association between the ser-9-gly polymorphism of the D3 dopaminergic receptor and schizophrenia].
Topics: Case-Control Studies; Female; Gene Frequency; Genotype; Glycine; Humans; Male; Polymorphism, Genetic; Receptors, Dopamine D2; Receptors, Dopamine D3; Schizophrenia; Sequence Analysis, DNA; Serine | 2001 |
Identification of essential residues for catalysis of rat intestinal phospholipase B/lipase.
Topics: Amino Acids; Animals; Aspartic Acid; Catalytic Domain; COS Cells; Enzyme Activation; Glycine; Guinea Pigs; Histidine; Intestines; Lysophospholipase; Mutagenesis, Site-Directed; Rabbits; Rats; Repetitive Sequences, Amino Acid; Serine; Threonine | 2001 |
cis-Inhibition of proteasomal degradation by viral repeats: impact of length and amino acid composition.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Cysteine Endopeptidases; DNA-Binding Proteins; Epstein-Barr Virus Nuclear Antigens; Female; Glycine; HeLa Cells; Humans; I-kappa B Proteins; Molecular Sequence Data; Molecular Weight; Multienzyme Complexes; NF-KappaB Inhibitor alpha; Proteasome Endopeptidase Complex; Protein Conformation; Protein Processing, Post-Translational; Repetitive Sequences, Amino Acid; Serine; Transfection; Tumor Necrosis Factor-alpha; Ubiquitins; Valine; Viral Proteins | 2001 |
Substrate analogs incorporating beta-amino acids: potential application for peptidase inhibition.
Topics: Animals; Bradykinin; Coronary Vessels; Fluorescent Dyes; Glycine; Metalloendopeptidases; Phenylalanine; Receptor, Bradykinin B2; Receptors, Bradykinin; Serine; Swine | 2001 |
Uptake of glycine by non-mycorrhizal Lolium perenne.
Topics: Amino Sugars; Gas Chromatography-Mass Spectrometry; Glucose; Glycine; Hydrogen-Ion Concentration; Isotope Labeling; Lolium; Nitrogen; Nitrogen Isotopes; Plant Leaves; Plant Proteins; Quaternary Ammonium Compounds; Serine; Sucrose; Transaminases | 2001 |
Studies on analogs of a peptide derived from alpha-fetoprotein having antigrowth properties.
Topics: Alanine; alpha-Fetoproteins; Animals; Antineoplastic Agents; Chromatography, Gel; Cysteine; Dose-Response Relationship, Drug; Epitopes; Estrogens; Female; Glycine; Humans; Hydrogen-Ion Concentration; Mice; Peptides; Protein Structure, Secondary; Serine; Time Factors; Uterus | 2001 |
The myoglobin of primates. I. Hylobates agilis (gibbon).
Topics: Amino Acid Sequence; Amino Acids; Animals; Glycine; Humans; Hylobates; Molecular Sequence Data; Myoglobin; Peptide Mapping; Primates; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Trypsin | 1971 |
Membrane interactions of mutated forms of the influenza fusion peptide.
Topics: Alanine; Amino Acid Sequence; Deuterium; Glutamic Acid; Glycine; Hemagglutinin Glycoproteins, Influenza Virus; Kinetics; Lipid Bilayers; Membrane Fusion; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Phosphorus Isotopes; Protein Conformation; Protein Structure, Secondary; Serine; Spectroscopy, Fourier Transform Infrared; Valine; Viral Fusion Proteins | 2001 |
Induction of mycosporine-like amino acids (MAAs) in cyanobacteria by solar ultraviolet-B radiation.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Circadian Rhythm; Cyanobacteria; Glycine; Serine; Species Specificity; Spectrophotometry; Sunlight; Ultraviolet Rays | 2001 |
Molecular and cellular physiology of the dissociation of atrial natriuretic peptide from guanylyl cyclase a receptors.
Topics: Alanine; Animals; Atrial Natriuretic Factor; Binding, Competitive; Catalysis; Cell Membrane; Cells, Cultured; CHO Cells; Cricetinae; Cyclic GMP; Cytoplasm; Gene Deletion; Glycine; Guanylate Cyclase; Kinetics; Ligands; Mutagenesis, Site-Directed; Mutation; Point Mutation; Protein Binding; Protein Structure, Tertiary; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Serine; Temperature; Time Factors; Transfection | 2001 |
The Calpha ---H...O hydrogen bond: a determinant of stability and specificity in transmembrane helix interactions.
Topics: Amino Acid Sequence; Glycine; Hydrogen Bonding; Membrane Proteins; Protein Conformation; Serine; Threonine | 2001 |
Glycine, serine, and leucine metabolism in different regions of rat central nervous system.
Topics: Animals; Central Nervous System; Glycine; In Vitro Techniques; Leucine; Nerve Tissue Proteins; Oxidation-Reduction; Rats; Rats, Wistar; Serine | 2001 |
The biotinyl domain of Escherichia coli acetyl-CoA carboxylase. Evidence that the "thumb" structure id essential and that the domain functions as a dimer.
Topics: Acetyl-CoA Carboxylase; Amino Acid Sequence; Biotinylation; Carrier Proteins; Escherichia coli; Fatty Acid Synthase, Type II; Genetic Complementation Test; Glycine; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Temperature | 2001 |
The role of serine hydroxymethyltransferase isozymes in one-carbon metabolism in MCF-7 cells as determined by (13)C NMR.
Topics: Breast Neoplasms; Carbon Isotopes; Cytosol; Female; Formates; Glycine; Glycine Hydroxymethyltransferase; Humans; Isoenzymes; Magnetic Resonance Spectroscopy; Mitochondria; Models, Biological; Purines; Serine; Substrate Specificity; Thymidine Monophosphate; Tumor Cells, Cultured | 2001 |
Alanine synthesis from glyceraldehyde and ammonium ion in aqueous solution.
Topics: Acetylcysteine; Alanine; Evolution, Chemical; Evolution, Molecular; Formates; Glyceraldehyde; Glycine; Glycolates; Lactic Acid; Quaternary Ammonium Compounds; Serine; Sulfhydryl Compounds | 1985 |
Determination of free intracellular amino acids in single mouse peritoneal macrophages after naphthalene-2,3-dicarboxaldehyde derivatization by capillary zone electrophoresis with electrochemical detection.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cell Extracts; Electrochemistry; Electrophoresis, Capillary; Glutamic Acid; Glycine; Intracellular Fluid; Macrophages, Peritoneal; Mice; Naphthalenes; Serine; Taurine | 2001 |
Phenotypic heterogeneity and adverse effects of serine treatment in 3-phosphoglycerate dehydrogenase deficiency: report on two siblings.
Topics: Amino Acids; Carbohydrate Dehydrogenases; Cerebrospinal Fluid; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Glycine; Head; Humans; Infant; Infant, Newborn; Metabolism, Inborn Errors; Phenotype; Phosphoglycerate Dehydrogenase; Serine; Spasms, Infantile; Treatment Outcome | 2001 |
Uptake of D-serine by synaptosomal P2 fraction isolated from rat brain.
Topics: Alanine; Animals; Binding, Competitive; Brain; Carrier Proteins; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Isomerism; Male; Neurons; Neurotransmitter Agents; Pharmacokinetics; Rats; Rats, Wistar; Serine; Synaptosomes; Temperature; Tritium | 2001 |
ATP synthase F(1) sector rotation. Defective torque generation in the beta subunit Ser-174 to Phe mutant and its suppression by second mutations.
Topics: Actins; Adenosine Triphosphate; Alanine; Escherichia coli; Glycine; Hydrolysis; Isoleucine; Models, Molecular; Mutation; Phenylalanine; Protein Conformation; Protein Structure, Tertiary; Proton-Translocating ATPases; Serine; Time Factors | 2001 |
Amino acid metabolism of bovine blastocysts derived from parthenogenetically activated or in vitro fertilized oocytes.
Topics: Alanine; Amino Acids; Animals; Asparagine; Blastocyst; Cattle; Cryopreservation; Culture Techniques; Female; Fertilization in Vitro; Glutamic Acid; Glutamine; Glycine; Oocytes; Parthenogenesis; Serine | 1998 |
Lack of association between N-ras gene mutations and clinical prognosis in Brazilian children with acute lymphoblastic leukemia.
Topics: Amino Acid Substitution; Base Sequence; Bone Marrow Cells; Brazil; Child; Child, Preschool; Cloning, Molecular; Codon; DNA; DNA Primers; DNA Probes; Exons; Female; Genes, ras; Glycine; Humans; Male; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Mas; Serine | 2001 |
Precursor structure of cephalosporin acylase. Insights into autoproteolytic activation in a new N-terminal hydrolase family.
Topics: Binding Sites; Dimerization; Glycine; Models, Molecular; Multigene Family; Penicillin Amidase; Protein Binding; Protein Precursors; Protein Structure, Tertiary; Pseudomonas; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared; Threonine | 2002 |
Gly40Ser polymorphism of the glucagon receptor gene is associated with central adiposity in men.
Topics: Adipose Tissue; Adult; Aged; Body Composition; Body Constitution; Body Mass Index; Energy Metabolism; Glycine; Heterozygote; Humans; Insulin Resistance; Lipids; Logistic Models; Male; Middle Aged; Polymorphism, Genetic; Receptors, Glucagon; Serine | 2001 |
Aging, carotid artery distensibility, and the Ser422Gly elastin gene polymorphism in humans.
Topics: Aging; Carotid Arteries; Cohort Studies; Compliance; Elastin; Female; Genotype; Glycine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Radial Artery; Serine; Ultrasonography | 2001 |
Mutational analysis of conserved glycines 42 and 256 in Cephalosporium acremonium isopenicillin N synthase.
Topics: Acremonium; Alanine; Amino Acid Sequence; DNA Mutational Analysis; Glycine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidoreductases; Sequence Alignment; Serine; Temperature | 2001 |
Corneodesmosin, a component of epidermal corneocyte desmosomes, displays homophilic adhesive properties.
Topics: Amino Acid Motifs; Animals; Blotting, Western; Calcium; Cell Adhesion; Cell Movement; Desmosomes; DNA, Complementary; Dose-Response Relationship, Drug; Epidermis; Escherichia coli; Fibroblasts; Glutathione Transferase; Glycine; Glycoproteins; Humans; Immunoblotting; Intercellular Signaling Peptides and Proteins; Mice; Microscopy, Fluorescence; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Time Factors; Transfection; Trypsin | 2002 |
Crystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A "knock-out" allosteric enzyme.
Topics: Allosteric Site; Binding Sites; Computer Simulation; Crystallography, X-Ray; Glycerophosphates; Glycine; Hydrogen Bonding; Indoles; Kinetics; Ligands; Models, Chemical; Models, Molecular; Mutation; Proline; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Serine; Tryptophan Synthase | 2002 |
Polymorphisms in the platelet-endothelial cell adhesion molecule-1 (PECAM-1) gene, Asn563Ser and Gly670Arg, associated with myocardial infarction in the Japanese.
Topics: Amino Acid Substitution; Antigens, CD; Arginine; Asian People; Asparagine; Coronary Stenosis; Female; Gene Frequency; Genotype; Glycine; Humans; Japan; Linkage Disequilibrium; Male; Middle Aged; Mutation, Missense; Myocardial Infarction; Platelet Endothelial Cell Adhesion Molecule-1; Polymorphism, Genetic; Reference Values; Serine | 2001 |
Ser9Gly polymorphism in the dopamine D3 receptor gene is not associated with essential hypertension in the Japanese.
Topics: Adult; Aged; Alleles; Female; Genotype; Glycine; Humans; Hypertension; Japan; Leukocytes; Male; Middle Aged; Models, Genetic; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Receptors, Dopamine D2; Receptors, Dopamine D3; Serine | 2002 |
Genome analysis: RNA recognition motif (RRM) and K homology (KH) domain RNA-binding proteins from the flowering plant Arabidopsis thaliana.
Topics: Amino Acid Motifs; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Arginine; Binding Sites; Genome, Plant; Genomics; Glycine; Heterogeneous-Nuclear Ribonucleoproteins; Molecular Sequence Data; Molecular Weight; Phylogeny; Poly A; Protein Binding; Protein Structure, Tertiary; Ribonucleoproteins; RNA-Binding Proteins; RNA, Plant; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship | 2002 |
Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits.
Topics: Animals; Calcium; Cations, Divalent; Central Nervous System; Cloning, Molecular; Electrophysiology; Glutamic Acid; Glycine; Immunohistochemistry; In Situ Hybridization; Ion Transport; Magnesium; Molecular Sequence Data; N-Methylaspartate; Neurons; Oocytes; Protein Subunits; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sequence Homology; Serine; Substrate Specificity; Xenopus laevis | 2002 |
Mutation of bcl-x gene in non-Hodgkin's lymphoma.
Topics: Apoptosis; bcl-X Protein; Glycine; Humans; Lymphoma, Non-Hodgkin; Mutation; Mutation, Missense; Point Mutation; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Serine | 2002 |
Polychromatic action spectrum for the induction of a mycosporine-like amino acid in a rice-field cyanobacterium, Anabaena sp.
Topics: Amino Acids; Anabaena; Chromatography, High Pressure Liquid; Environment, Controlled; Glycine; Oryza; Serine; Spectrophotometry, Atomic; Ultraviolet Rays | 2002 |
Substitution of Gly-548 to Ala in the substrate binding pocket of prothrombin Perijá leads to the loss of thrombin proteolytic activity.
Topics: Alanine; Amino Acid Substitution; Antithrombin III; Arginine; Binding Sites; Catalytic Domain; Codon; DNA Mutational Analysis; Enzyme Activation; Enzyme Inhibitors; Exons; Factor V; Factor Xa; Glycine; Humans; Models, Molecular; Pipecolic Acids; Polymorphism, Single-Stranded Conformational; Protein Conformation; Prothrombin; Serine; Structure-Activity Relationship; Sulfonamides; Thrombin | 2002 |
Crystal structure of binary and ternary complexes of serine hydroxymethyltransferase from Bacillus stearothermophilus: insights into the catalytic mechanism.
Topics: Aldehydes; Animals; Catalysis; Catalytic Domain; Crystallography, X-Ray; Dimerization; Escherichia coli; Geobacillus stearothermophilus; Glycine; Glycine Hydroxymethyltransferase; Histidine; Leucovorin; Mice; Models, Chemical; Models, Molecular; Protein Binding; Protein Conformation; Protein Structure, Secondary; Serine | 2002 |
Toll-like receptor 4-MD-2 complex mediates the signal transduction induced by flavolipin, an amino acid-containing lipid unique to Flavobacterium meningosepticum.
Topics: Animals; Antigens, Surface; Cell Line; Drosophila Proteins; Flavobacterium; Glycine; Lipids; Lipopolysaccharide Receptors; Lipoproteins; Lymphocyte Antigen 96; Macromolecular Substances; Membrane Glycoproteins; Mice; NF-kappa B; Receptors, Cell Surface; Serine; Signal Transduction; Stereoisomerism; Toll-Like Receptor 4; Toll-Like Receptors; Transfection | 2002 |
Racemic amino acids from the ultraviolet photolysis of interstellar ice analogues.
Topics: Alanine; Amino Acids; Glycine; Ice; Meteoroids; Molecular Conformation; Photochemistry; Serine; Ultraviolet Rays | 2002 |
A comparison in normal individuals and sickle cell patients of reduced glutathione precursors and their transport between plasma and red cells.
Topics: Adult; Amino Acid Transport System ASC; Amino Acid Transport System L; Anemia, Sickle Cell; Biological Transport; Carbon Monoxide; Cysteine; Enzyme Inhibitors; Erythrocytes; Female; Glutamic Acid; Glutamine; Glutathione; Glycine; Humans; Male; Middle Aged; Oxygen; Protein Kinase Inhibitors; Protein Kinases; Serine; Staurosporine | 2000 |
A mutation in the human neurofilament M gene in Parkinson's disease that suggests a role for the cytoskeleton in neuronal degeneration.
Topics: Adult; Age of Onset; Brain; Cytoskeleton; DNA Mutational Analysis; Female; Genetic Testing; Glycine; Humans; Male; Molecular Sequence Data; Mutation; Neurofilament Proteins; Neurons; Parkinsonian Disorders; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Serine | 2002 |
Glycine residues in potassium channel-like selectivity filters determine potassium selectivity in four-loop-per-subunit HKT transporters from plants.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Arabidopsis; Arabidopsis Proteins; Cation Transport Proteins; Glycine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oocytes; Phylogeny; Plant Proteins; Plasmids; Point Mutation; Potassium; Potassium Channels; Protein Structure, Tertiary; Salts; Serine; Symporters; Xenopus | 2002 |
Crystallinity and solubility characteristics of hydroxyapatite adsorbed amino acid.
Topics: Adsorption; Amino Acids; Aspartic Acid; Crystallization; Durapatite; Glutamic Acid; Glycine; Materials Testing; Microscopy, Electron, Scanning; Models, Chemical; Serine; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2002 |
Calcineurin acts via the C-terminus of NR2A to modulate desensitization of NMDA receptors.
Topics: Calcineurin; Calcineurin Inhibitors; Cell Line; Enzyme Inhibitors; Glycine; Humans; Mutation; Organometallic Compounds; Phenanthrolines; Protein Tyrosine Phosphatases; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Serine; Vanadium | 2002 |
Release of excitatory amino acids in the penumbra of a focal cortical necrosis.
Topics: Alanine; Animals; Aspartic Acid; Cerebral Cortex; Excitatory Amino Acids; Glutamic Acid; Glycine; Male; Microdialysis; Necrosis; Rats; Serine | 2002 |
A general method for determining the contribution of split pathways in metabolite production in the yeast Saccharomyces cerevisiae.
Topics: Amino Acids; Biomedical Engineering; Carbon Isotopes; Cell Compartmentation; Glycine; Glycine Hydroxymethyltransferase; Kinetics; Magnetic Resonance Spectroscopy; Models, Biological; Saccharomyces cerevisiae; Serine | 2002 |
Solid-phase oligosaccharide and glycopeptide synthesis using glycosynthases.
Topics: Acetylation; Amination; Amino Acid Sequence; beta-Glucosidase; Chromatography, High Pressure Liquid; Glycine; Glycopeptides; Glycosylation; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Mutation; Oligosaccharides; Peptides; Resins, Plant; Rhizobium; Serine | 2002 |
Homonuclear zero-quantum recoupling in fast magic-angle spinning nuclear magnetic resonance.
Topics: Alanine; Carbon Isotopes; Glycine; Magnetic Resonance Spectroscopy; Mathematics; Serine; Tyrosine | 2002 |
Flow injection chemiluminescence determination of amino acids by oxidation with N-bromosuccinimide.
Topics: Amino Acids; Anions; Arginine; Bromosuccinimide; Cations; Energy Transfer; Flow Injection Analysis; Glycine; Luminescent Measurements; Oxidation-Reduction; Sensitivity and Specificity; Serine; Threonine | 2002 |
Synthesis of Ser-His-Gly.DNA conjugates.
Topics: DNA; Glycine; Histidine; Nucleic Acid Conformation; Oligonucleotides; Oligopeptides; Serine; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet | 2002 |
Congenital microcephaly and seizures due to 3-phosphoglycerate dehydrogenase deficiency: outcome of treatment with amino acids.
Topics: Carbohydrate Dehydrogenases; Child; Child, Preschool; Female; Glycine; Humans; Infant; Male; Microcephaly; Phosphoglycerate Dehydrogenase; Psychomotor Disorders; Seizures; Serine; Treatment Outcome | 2002 |
Nac-mediated repression of the serA promoter of Escherichia coli.
Topics: Amino Acid Sequence; Bacterial Proteins; Carrier Proteins; Caseins; Culture Media; DNA-Binding Proteins; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genes, Suppressor; Glutamine; Glycine; Humans; Molecular Sequence Data; Nitrogen; Nitrogen Fixation; PII Nitrogen Regulatory Proteins; Promoter Regions, Genetic; Protein Hydrolysates; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology; Serine; Transcription Factors | 2002 |
Down-regulation of complement receptor 3 and major histocompatibility complex I and II antigen-like immunoreactivity accompanies ramification in isolated rat microglia.
Topics: Animals; Antibodies, Monoclonal; Cell Differentiation; Cell Division; Cells, Cultured; Culture Media; Down-Regulation; Genes, MHC Class I; Genes, MHC Class II; Glycine; Granulocyte-Macrophage Colony-Stimulating Factor; Immunohistochemistry; Lipopolysaccharides; Macrophage-1 Antigen; Microglia; Rats; Rats, Sprague-Dawley; Serine | 2002 |
Severe impairment of NMDA receptor function in mice carrying targeted point mutations in the glycine binding site results in drug-resistant nonhabituating hyperactivity.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Binding Sites; Binding, Competitive; Biogenic Amines; Corpus Striatum; Dose-Response Relationship, Drug; Drug Resistance; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; Gene Targeting; Glutamic Acid; Glycine; Heterozygote; Hippocampus; Hyperkinesis; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Neurologic Mutants; Neurons; Patch-Clamp Techniques; Phenotype; Point Mutation; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism; Stereotyped Behavior | 2002 |
Purification and characterization of two polymorphic variants of short chain acyl-CoA dehydrogenase reveal reduction of catalytic activity and stability of the Gly185Ser enzyme.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Amino Acid Substitution; Arginine; Catalysis; Chaperonin 10; Chaperonin 60; Circular Dichroism; Enzyme Stability; Escherichia coli; Fatty Acids, Volatile; Genetic Variation; Glycine; Guanidine; Hot Temperature; Humans; Oxidation-Reduction; Polymorphism, Genetic; Protein Denaturation; Protein Folding; Recombinant Proteins; Serine; Spectrophotometry; Tryptophan | 2002 |
Mechanism of regulation of casein kinase I activity by group I metabotropic glutamate receptors.
Topics: Animals; Calcineurin; Casein Kinases; Chelating Agents; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cyclosporine; Dopamine and cAMP-Regulated Phosphoprotein 32; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Excitatory Amino Acid Agonists; Glycine; In Vitro Techniques; Male; Mice; Neostriatum; Nerve Tissue Proteins; Peptide Mapping; Phosphoproteins; Phosphorylation; Protein Kinases; Pyrrolidinones; Receptors, Metabotropic Glutamate; Resorcinols; Serine; Signal Transduction; Threonine; Tumor Cells, Cultured; Type C Phospholipases | 2002 |
Identification of a tyrosine in the agonist binding site of the homomeric rho1 gamma-aminobutyric acid (GABA) receptor that, when mutated, produces spontaneous opening.
Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Crotonates; Dimerization; Dose-Response Relationship, Drug; Electrophysiology; Ethyl Methanesulfonate; GABA Antagonists; Glycine; Humans; Imidazoles; Mesylates; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oocytes; Organophosphorus Compounds; Picrotoxin; Protein Binding; Receptors, GABA-B; RNA, Complementary; Serine; Transcription, Genetic; Tryptophan; Tyrosine; Xenopus laevis | 2002 |
Induction of tumor-reactive CTL by C-side chain variants of the CTL epitope HER-2/neu protooncogene (369-377) selected by molecular modeling of the peptide: HLA-A2 complex.
Topics: Adjuvants, Immunologic; Alanine; Amino Acid Substitution; Antigen Presentation; Antigens, Neoplasm; Apoptosis; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Line; Cell Survival; Cytotoxicity, Immunologic; Epitopes, T-Lymphocyte; Genes, erbB-2; Glycine; HLA-A2 Antigen; Humans; Interferon-gamma; Lymphocyte Activation; Lysine; Models, Molecular; Peptide Fragments; Serine; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured | 2002 |
Disruption of the SHM2 gene, encoding one of two serine hydroxymethyltransferase isoenzymes, reduces the flux from glycine to serine in Ashbya gossypii.
Topics: Amino Acid Sequence; Carbon Radioisotopes; Fungal Proteins; Gene Targeting; Genes, Fungal; Glycine; Glycine Hydroxymethyltransferase; Isoenzymes; Molecular Sequence Data; Promoter Regions, Genetic; Riboflavin; Saccharomycetales; Sequence Alignment; Sequence Analysis, DNA; Serine; Threonine | 2003 |
Functional study of a recombinant form of human LHbeta-subunit variant carrying the Gly(102)Ser mutation found in Asian populations.
Topics: Animals; Asia; Asian People; Cells, Cultured; Cyclic AMP; Denmark; Finland; Genetic Variation; Glycine; Humans; India; Leydig Cell Tumor; Luteinizing Hormone, beta Subunit; Mice; Point Mutation; Progesterone; Receptors, LH; Recombinant Proteins; Rwanda; Serine; Signal Transduction | 2002 |
Folate cofactors regulate serine metabolism in fetal ovine hepatocytes.
Topics: Animals; Bromodeoxyuridine; Folic Acid; Glycine; Hepatocytes; Serine; Sheep | 2002 |
Photorespiratory NH(4)(+) production in leaves of wild-type and glutamine synthetase 2 antisense oilseed rape.
Topics: Ammonia; Antisense Elements (Genetics); Brassica napus; Carbon Dioxide; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Glycine; Immunohistochemistry; Light; Microscopy, Electron; Models, Biological; Oxygen; Oxygen Consumption; Photosynthesis; Plant Leaves; Plant Transpiration; Plants, Genetically Modified; Quaternary Ammonium Compounds; Ribulose-Bisphosphate Carboxylase; Serine; Temperature | 2002 |
Taste enhancements between various amino acids and IMP.
Topics: Adult; Alanine; Amino Acids; Dose-Response Relationship, Drug; Female; Glycine; Humans; Inosine Monophosphate; Male; Phenyl Ethers; Propionates; Serine; Taste; Taste Buds; Taste Threshold; Time Factors | 2002 |
Amino acid content of cell cultures infected with Cowdria ruminantium propagated in a protein-free medium.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Bacteriological Techniques; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media, Serum-Free; Ehrlichia ruminantium; Glutamine; Glycine; Heartwater Disease; Proline; Ruminants; Serine; Tryptophan | 2002 |
Posttranslational modification of serine to formylglycine in bacterial sulfatases. Recognition of the modification motif by the iron-sulfur protein AtsB.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Arylsulfatases; beta-Galactosidase; Blotting, Western; Cysteine; Cytosol; Dose-Response Relationship, Drug; Escherichia coli; Glutathione Transferase; Glycine; Iron-Sulfur Proteins; Klebsiella pneumoniae; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Protein Binding; Protein Processing, Post-Translational; Protein Sorting Signals; Serine; Subcellular Fractions; Sulfatases; Two-Hybrid System Techniques | 2003 |
Utilization of glycine and serine as nitrogen sources in the roots of Zea mays and Chamaegigas intrepidus.
Topics: Glycine; Magnetic Resonance Spectroscopy; Nitrogen; Plant Roots; Scrophulariaceae; Serine; Zea mays | 2002 |
Excitatory amino acid release in the spinal cord caused by plantar incision in the rat.
Topics: Animals; Asparagine; Aspartic Acid; Dermatologic Surgical Procedures; Glutamic Acid; Glutamine; Glycine; Male; Microdialysis; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord | 2002 |
Conserved proline residue at position 189 in cone visual pigments as a determinant of molecular properties different from rhodopsins.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Avian Proteins; Cell Line; Chickens; Conserved Sequence; Epitopes; Eye Proteins; Genetic Vectors; Glycine; Humans; Isoleucine; Leucine; Mice; Proline; Retinal Cone Photoreceptor Cells; Retinal Pigments; Rhodopsin; Serine; Spectrophotometry; Thermodynamics; Valine | 2002 |
Serine metabolism in human pregnancy.
Topics: Adult; Carbon Isotopes; Fasting; Female; Glutamine; Glycine; Humans; Isoleucine; Kinetics; Leucine; Nitrogen Isotopes; Oxidation-Reduction; Pregnancy; Serine; Urea; Valine | 2003 |
Recognition of a specific self-peptide: self-MHC class II complex is critical for positive selection of thymocytes expressing the D10 TCR.
Topics: Alleles; Animals; Arginine; Autoantigens; Cell Differentiation; Cell Line; Complementarity Determining Regions; Conalbumin; Down-Regulation; Epitopes, T-Lymphocyte; Glycine; Histocompatibility Antigens Class II; Leucine; Lymphocyte Count; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Peptides; Point Mutation; Receptors, Antigen, T-Cell, alpha-beta; Serine; T-Lymphocyte Subsets; Thymus Gland; Transgenes | 2003 |
Bilateral pheochromocytomas and congenital anomalies associated with a de novo germline mutation in the von Hippel-Lindau gene.
Topics: Adrenal Gland Neoplasms; Amino Acid Substitution; Child; Cryptorchidism; Developmental Disabilities; Genes, Tumor Suppressor; Germ-Line Mutation; Glycine; Hearing Loss, Bilateral; Humans; Ligases; Male; Microcephaly; Multiple Endocrine Neoplasia Type 2a; Mutation, Missense; Pheochromocytoma; Serine; Syndrome; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; von Hippel-Lindau Disease; Von Hippel-Lindau Tumor Suppressor Protein | 2003 |
Evidence for functionally distinct synaptic NMDA receptors in ventromedial versus dorsolateral striatum.
Topics: Age Factors; Animals; Animals, Newborn; Corpus Striatum; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Kinetics; Limbic System; Male; Motor Neurons; Neurons, Afferent; Organ Culture Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synapses | 2003 |
The unusual catalytic triad of poliovirus protease 3C.
Topics: 3C Viral Proteases; Catalysis; Catalytic Domain; Cysteine; Cysteine Endopeptidases; Deuterium; Glutamic Acid; Glutamine; Glycine; Hydrogen-Ion Concentration; Kinetics; Methionine; Models, Chemical; Mutagenesis, Site-Directed; Poliovirus; Serine; Solvents; Substrate Specificity; Temperature; Thermodynamics; Viral Proteins | 2003 |
Evolution of feedback-inhibited beta /alpha barrel isoenzymes by gene duplication and a single mutation.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Alleles; Amino Acid Sequence; Amino Acids; Crystallography, X-Ray; Enzymes; Glycine; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Protein Isoforms; Protein Structure, Tertiary; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Serine; Tyrosine | 2003 |
In vitro lipolysis by human pancreatic lipase is specifically abolished by its inactive forms.
Topics: Anthracenes; Bile Acids and Salts; Colipases; Enzyme Inhibitors; Enzyme Reactivators; Fluorescent Dyes; Glycine; Humans; In Vitro Techniques; Lipase; Lipolysis; Mutation; Organophosphorus Compounds; Pancreas; Pancreatic Juice; Recombinant Proteins; Serine | 2003 |
Glycine tranporter-1 blockade potentiates NMDA-mediated responses in rat prefrontal cortical neurons in vitro and in vivo.
Topics: Amino Acid Transport Systems, Neutral; Animals; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; Glycine Plasma Membrane Transport Proteins; Iontophoresis; Male; N-Methylaspartate; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Prefrontal Cortex; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine | 2003 |
Reaction of 1-amino-2-methylenecyclopropane-1-carboxylate with 1-aminocyclopropane-1-carboxylate deaminase: analysis and mechanistic implications.
Topics: Alanine; Amino Acid Sequence; Carbon-Carbon Lyases; Carboxylic Acids; Catalysis; Chromatography, High Pressure Liquid; Cloning, Molecular; Crotonates; Cyclopropanes; Cysteine; Dithionitrobenzoic Acid; Glycine; Kinetics; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Pseudomonas; Recombinant Proteins; Serine; Titrimetry | 2003 |
Synthesis of C-linked glycopyranosyl serines via a chiral glycine enolate equivalent.
Topics: Alkylation; Galactosides; Glucosides; Glycine; Glycoconjugates; Glycopeptides; Glycosides; Monosaccharides; Serine | 2002 |
A Gly482Ser missense mutation in the peroxisome proliferator-activated receptor gamma coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians.
Topics: Adipocytes; Adipose Tissue; Adult; Alleles; Blood Glucose; Body Composition; Body Mass Index; Cell Size; Diabetes Mellitus, Type 2; Female; Gene Frequency; Glycine; Humans; Indians, North American; Insulin; Insulin Secretion; Lipid Peroxidation; Longitudinal Studies; Male; Mutation, Missense; Obesity; Sequence Analysis, DNA; Serine; Transcription Factors | 2003 |
Random-order ternary complex reaction mechanism of serine acetyltransferase from Escherichia coli.
Topics: Acetyl Coenzyme A; Acetyltransferases; Binding, Competitive; Catalysis; Coenzyme A; Enzyme Inhibitors; Escherichia coli Proteins; Esters; Glycine; Hydrolysis; Kinetics; Phosphorus Isotopes; Protein Structure, Secondary; Serine; Serine O-Acetyltransferase; Substrate Specificity | 2003 |
[The role of glycine binding site in NMDA receptor--interactions between NMDA and D-serine in artificial anoxia/agycemia rat hippocampus].
Topics: Animals; Binding Sites; Glycine; Hippocampus; Hypoxia; In Vitro Techniques; N-Methylaspartate; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine | 2003 |
Function of the loop residue Thr792 in human DNA topoisomerase II alpha.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Catalysis; Cell Division; Cysteine; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Complementary; Dose-Response Relationship, Drug; Fungal Proteins; Genetic Complementation Test; Glutamic Acid; Glycine; Humans; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Plasmids; Poly-ADP-Ribose Binding Proteins; Saccharomyces cerevisiae; Serine; Threonine; Valine | 2003 |
Wavelength-dependent induction of a mycosporine-like amino acid in a rice-field cyanobacterium, Nostoc commune: role of inhibitors and salt stress.
Topics: Amino Acids; Chlorophyll; Chromatography, High Pressure Liquid; Cyanobacteria; Enzyme Inhibitors; Glycine; Oryza; Osmotic Pressure; Serine; Sodium Chloride; Spectrophotometry; Ultraviolet Rays | 2003 |
Investigating the regulation of one-carbon metabolism in Arabidopsis thaliana.
Topics: Aminohydrolases; Arabidopsis; Carbon; Carbon Dioxide; Carbon Isotopes; Formate Dehydrogenases; Formate-Tetrahydrofolate Ligase; Formates; Gene Expression Regulation, Enzymologic; Glycine; Glycine Hydroxymethyltransferase; Homocysteine S-Methyltransferase; Magnetic Resonance Spectroscopy; Methylenetetrahydrofolate Dehydrogenase (NADP); Methyltransferases; Multienzyme Complexes; Mutation; Plant Shoots; Plants, Genetically Modified; Serine | 2003 |
G12S and H50R variations are polymorphisms in the SDHD gene.
Topics: Amino Acid Substitution; Arginine; Electron Transport Complex II; Female; Genetic Variation; Glycine; Histidine; Humans; Multienzyme Complexes; Oxidoreductases; Polymorphism, Genetic; Serine; Succinate Dehydrogenase | 2003 |
S20G mutation of the amylin gene is associated with a lower body mass index in Korean type 2 diabetic patients.
Topics: Age of Onset; Amino Acid Substitution; Amyloid; Asian People; Body Mass Index; Diabetes Mellitus, Type 2; Female; Glycine; Humans; Islet Amyloid Polypeptide; Korea; Male; Middle Aged; Mutation, Missense; Reference Values; Serine | 2003 |
A requirement for anaerobically induced redox functions during aerobic growth of Escherichia coli with serine, glycine and leucine as carbon source.
Topics: Anaerobiosis; DNA, Bacterial; Escherichia coli; Genetic Complementation Test; Glycine; L-Serine Dehydratase; Leucine; Mutation; Oxidation-Reduction; Polymerase Chain Reaction; Serine | 2003 |
[Cell wall components of gramicidin S resistant Staphylococcus aureus].
Topics: Anti-Bacterial Agents; Cell Wall; Drug Resistance, Bacterial; Glutamic Acid; Glycine; Gramicidin; Peptidoglycan; Serine; Staphylococcus aureus; Teichoic Acids | 2003 |
The polymorphism Gly574Ser in the transcription factor HNF-1alpha is not a marker of adult-onset ketosis-prone atypical diabetes in Afro-Caribbean patients.
Topics: Adult; Africa; Amino Acid Substitution; Black People; Caribbean Region; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; DNA-Binding Proteins; Gene Frequency; Genetic Markers; Glycine; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Mutation, Missense; Nuclear Proteins; Polymorphism, Single Nucleotide; Serine; Transcription Factors | 2003 |
Novel variants of the IL-10 receptor 1 affect inhibition of monocyte TNF-alpha production.
Topics: Amino Acid Substitution; Arginine; Crohn Disease; DNA, Complementary; Gene Frequency; Genetic Variation; Genotype; Glycine; Haplotypes; Humans; Interleukin-10; Macromolecular Substances; Models, Molecular; Monocytes; Polymorphism, Single Nucleotide; Receptors, Interleukin; Receptors, Interleukin-10; Serine; Tumor Necrosis Factor-alpha | 2003 |
Familial hypertrophic cardiomyopathy mutations in troponin I (K183D, G203S, K206Q) enhance filament sliding.
Topics: Actin Cytoskeleton; Amino Acid Sequence; Amino Acid Substitution; Animals; Calcium; Cardiomyopathy, Hypertrophic, Familial; Cattle; Glutamine; Glycine; Lysine; Male; Myocardium; Point Mutation; Rabbits; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sarcomeres; Sequence Deletion; Serine; Signal Transduction; Troponin I | 2003 |
Roles of individual amino acids in helix 14 of the membrane domain of proton-translocating transhydrogenase from Escherichia coli as deduced from cysteine mutagenesis.
Topics: Alkaline Phosphatase; Amino Acids; Binding Sites; Cysteine; Escherichia coli; Ethylmaleimide; Glycine; Models, Chemical; Mutagenesis, Site-Directed; Mutation; NAD; NADP; NADP Transhydrogenases; Plasmids; Protein Structure, Tertiary; Protons; Serine | 2003 |
The functional integrity of the serpin domain of C1-inhibitor depends on the unique N-terminal domain, as revealed by a pathological mutant.
Topics: Amino Acid Sequence; Base Sequence; Blotting, Western; Centrifugation, Density Gradient; Complement C1 Inactivator Proteins; Complement C1 Inhibitor Protein; Crystallography, X-Ray; Cysteine; Disulfides; DNA; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Exons; Gene Deletion; Glycine; Heparin; Hot Temperature; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Phenotype; Plasmids; Polymerase Chain Reaction; Proline; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Serine; Serpins; Sucrose; Temperature | 2003 |
Agrin is a chimeric proteoglycan with the attachment sites for heparan sulfate/chondroitin sulfate located in two multiple serine-glycine clusters.
Topics: Agrin; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Chickens; Chondroitin Sulfates; Electrophoresis, Polyacrylamide Gel; Glycine; Glycosylation; Heparitin Sulfate; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Plasmids; Protein Structure, Tertiary; Proteoglycans; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Threonine | 2003 |
Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia.
Topics: Adolescent; Adult; Age Factors; Biomarkers; Brief Psychiatric Rating Scale; Chromatography, High Pressure Liquid; Female; Glycine; Humans; Male; Middle Aged; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Sex Factors; Stereoisomerism | 2003 |
Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core.
Topics: Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Disulfides; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Binding; Protein Conformation; Protein Subunits; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sequence Alignment; Serine | 2003 |
Spectrum of CBS mutations in 16 homocystinuric patients from the Iberian Peninsula: high prevalence of T191M and absence of I278T or G307S.
Topics: Adolescent; Adult; Amino Acid Sequence; Amino Acid Substitution; Animals; Child; Child, Preschool; Cystathionine beta-Synthase; Female; Genotype; Glycine; Homocystinuria; Humans; Infant; Isoleucine; Male; Methionine; Middle Aged; Molecular Sequence Data; Phenotype; Portugal; Prevalence; Serine; Spain; Threonine | 2003 |
L-Serine and glycine based ceramide analogues as transdermal permeation enhancers: polar head size and hydrogen bonding.
Topics: Administration, Cutaneous; Azepines; Ceramides; Chromatography, High Pressure Liquid; Diffusion Chambers, Culture; Excipients; Glycine; Humans; Hydrogen Bonding; In Vitro Techniques; Indicators and Reagents; Serine; Skin Absorption; Structure-Activity Relationship; Theophylline; Vasodilator Agents | 2003 |
Facilitation of spinal NMDA receptor currents by spillover of synaptically released glycine.
Topics: Analgesics; Animals; Anterior Horn Cells; Diffusion; Electric Stimulation; Evoked Potentials; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Interneurons; Neural Inhibition; Opioid Peptides; Pain Measurement; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Spinal Cord; Synapses; Synaptic Transmission; Temperature | 2003 |
In vitro regulation of rat derived microglia.
Topics: alpha-Tocopherol; Animals; Ascorbic Acid; Cells, Cultured; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Glycine; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Hydrocortisone; Microglia; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Serine | 2003 |
Thapsigargin selectively rescues the trafficking defective LQT2 channels G601S and F805C.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Cation Transport Proteins; Cell Line; Cell Membrane; Cell Nucleus; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Glycine; Humans; Long QT Syndrome; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Transport; Recombinant Proteins; Serine; Thapsigargin; Trans-Activators; Transcriptional Regulator ERG | 2003 |
Preparation of recombinant rat eosinophil-associated ribonuclease-1 and -2 and analysis of their biological activities.
Topics: Amino Acid Sequence; Animals; Blood Bactericidal Activity; Blood Proteins; Cattle; Eosinophil Granule Proteins; Eosinophils; Escherichia coli; Glycine; Granulocyte-Macrophage Colony-Stimulating Factor; Hot Temperature; Kinetics; Rats; Recombinant Proteins; Ribonuclease, Pancreatic; Ribonucleases; RNA, Transfer, Met; Saccharomyces cerevisiae; Serine | 2003 |
Gly511 to Ser substitution in the COL1A1 gene in osteogenesis imperfecta type III patient with increased turnover of collagen.
Topics: Blotting, Western; Child, Preschool; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Culture Media; Culture Media, Conditioned; Dipeptidases; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Family Health; Female; Fibroblasts; Genotype; Glycine; Heterozygote; Humans; Integrin beta1; Models, Genetic; Mutation; Osteogenesis Imperfecta; Phenotype; Polymerase Chain Reaction; Receptor, IGF Type 1; Serine; Skin | 2003 |
Analysis of Gly40Ser polymorphism of the glucagon receptor (GCGR) gene in different ethnic groups.
Topics: Adult; Asian People; Black People; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus; Female; Glucose Intolerance; Glycine; Humans; Hypertension; London; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Receptors, Glucagon; Serine | 2003 |
Lipoprotein lipase activity and common gene variants in severely hypertriglyceridemic patients with and without diabetes.
Topics: Adult; Apolipoproteins; Asparagine; Aspartic Acid; Diabetes Complications; Diabetes Mellitus; Female; Genetic Variation; Glutamic Acid; Glycine; Humans; Hyperlipoproteinemia Type IV; Lipoprotein Lipase; Male; Middle Aged; Phenotype; Serine; Severity of Illness Index | 2003 |
Modeling domino effects in enzymes: molecular basis of the substrate specificity of the bacterial metallo-beta-lactamases IMP-1 and IMP-6.
Topics: Amino Acid Substitution; beta-Lactamases; Computational Biology; Computer Simulation; Enzyme Stability; Glycine; Hot Temperature; Models, Chemical; Models, Molecular; Mutation; Pseudomonas aeruginosa; Serine; Substrate Specificity; Temperature; Thermodynamics | 2003 |
Glycine facilitates transmitter release at developing synapses: a patch clamp study from Purkinje neurons of the newborn rat.
Topics: Acetylcholine; Alanine; Anesthetics, Local; Animals; Animals, Newborn; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Electric Conductivity; Excitatory Postsynaptic Potentials; Glycine; Glycine Agents; In Vitro Techniques; Neural Inhibition; Neurotransmitter Agents; Patch-Clamp Techniques; Potassium; Purkinje Cells; Rats; Rats, Wistar; Serine; Strychnine; Synapses; Synaptic Transmission; Taurine; Tetrodotoxin; Time Factors; Vasodilator Agents | 2003 |
Mutagenesis of a Gly-Ser cleavage site in MUC1 inhibits ectodomain shedding.
Topics: Amino Acid Sequence; Animals; Breast Neoplasms; COS Cells; Glycine; Humans; Lung Neoplasms; Mice; Mucin-1; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Serine; Transfection; Tumor Cells, Cultured | 2003 |
Evidence for strychnine-sensitive glycine receptors in human amygdala.
Topics: Acetylcholine; Adult; Amygdala; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glycine; Humans; Immunohistochemistry; In Vitro Techniques; Middle Aged; Neocortex; Protein Subunits; Rats; Receptors, Glycine; Retina; Serine; Strychnine; Taurine; Tissue Distribution | 2003 |
Effects of endogenous agonists, glycine and D-serine, on in vivo specific binding of [11C]L-703,717, a PET radioligand for the glycine-binding site of NMDA receptors.
Topics: Amino Acid Transport Systems, Neutral; Animals; Binding Sites; Binding, Competitive; Carbon Radioisotopes; Cerebellum; D-Amino-Acid Oxidase; Extracellular Fluid; Glycine; Glycine Plasma Membrane Transport Proteins; Hydroxyquinolines; Ligands; Male; Mice; Mice, Knockout; Neurons; Quinolones; Radioligand Assay; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Stereoisomerism; Synaptic Transmission; Up-Regulation | 2003 |
Conversion of a PLP-dependent racemase into an aldolase by a single active site mutation.
Topics: Alanine Racemase; Amino Acid Substitution; Benzaldehydes; Binding Sites; Fructose-Bisphosphate Aldolase; Glycine; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Serine | 2003 |
Gas-phase basicity of glycine, alanine, proline, serine, lysine, histidine and some of their peptides by the thermokinetic method.
Topics: Alanine; Amino Acids; Gases; Glycine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Peptides; Proline; Protons; Serine; Thermodynamics | 2003 |
Serine acetyltransferase of Escherichia coli: substrate specificity and feedback control by cysteine.
Topics: Acetyl Coenzyme A; Acetyltransferases; Acyl Coenzyme A; Adenosine Triphosphate; Calorimetry; Cysteine; Escherichia coli; Feedback, Physiological; Glycine; Kinetics; Serine; Serine O-Acetyltransferase; Substrate Specificity; Threonine | 2003 |
On the structural and functional importance of the highly conserved Glu56 of Thermus thermophilus L4 ribosomal protein.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Catalytic Domain; Glutamic Acid; Glycine; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Structure, Secondary; Ribosomal Proteins; Ribosomes; Sequence Alignment; Serine; Thermus thermophilus | 2003 |
Essential glycine in the proton channel of Escherichia coli transhydrogenase.
Topics: Alanine; Amino Acid Sequence; Catalysis; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glycine; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADP; NADP Transhydrogenases; Protein Conformation; Protein Structure, Tertiary; Protons; Serine | 2003 |
The presence of the casein kinase II phosphorylation sites of Vpu enhances the CD4(+) T cell loss caused by the simian-human immunodeficiency virus SHIV(KU-lbMC33) in pig-tailed macaques.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Casein Kinase II; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Disease Models, Animal; Glycine; Green Fluorescent Proteins; HIV-1; Human Immunodeficiency Virus Proteins; Luminescent Proteins; Macaca nemestrina; Molecular Sequence Data; Mutation; Phosphorylation; Protein Serine-Threonine Kinases; Reassortant Viruses; Sequence Alignment; Serine; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Viral Load; Viral Regulatory and Accessory Proteins | 2003 |
Studies on the mechanism of the biosynthesis of serine.
Topics: Glycine; Serine | 1952 |
The Biosynthesis of Protein. I. Uptake of glycine, serine, valine and lysine by the mammary gland of the rabbit.
Topics: Animals; Glycine; Humans; Lysine; Mammary Glands, Human; Proteins; Rabbits; Serine; Valine | 1952 |
The in vivo conversion of glycine to serine.
Topics: Biochemical Phenomena; Fabaceae; Glycine; Serine | 1953 |
Inhibiting effects of amino acids and related compounds upon the growth of enterotoxigenic micrococci in cream pastry.
Topics: Acetates; Amino Acids; Cysteine; Foodborne Diseases; Glycine; Glycine Agents; Micrococcus; Serine | 1953 |
The conversion of glycine to serine by human liver tissue.
Topics: Biochemical Phenomena; Fabaceae; Glycine; Humans; Liver; Serine | 1953 |
The effect of cobalamin on the quantitative utilization of serine, glycine and formate for the synthesis of choline and methyl groups of methionine.
Topics: Choline; Fabaceae; Formates; Glycine; Hematinics; Methionine; Serine; Vitamin B 12 | 1953 |
The synthesis of glycine and serine by the rat.
Topics: Animals; Fabaceae; Glycine; Rats; Serine | 1953 |
The alanine, cystine, glycine and serine content of meat.
Topics: Alanine; Cystine; Glycine; Meat; Serine | 1953 |
Products formed from glycolic acid in plants.
Topics: Acetates; Glycine; Glycolates; Plants; Serine | 1953 |
Folic acid as coenzyme for the interconversion of serine and glycine.
Topics: Coenzymes; Fabaceae; Folic Acid; Glycine; Humans; Serine | 1953 |
Certain interrelationships in the metabolism of glycine and serine.
Topics: Fabaceae; Glycine; Serine | 1954 |
The synthesis of thymine and purines from serine and glycine in the rat.
Topics: Animals; Glycine; Metabolic Networks and Pathways; Purines; Rats; Serine; Thymine | 1954 |
The interconversion of serine and glycine: role of pteroylglutamic acid and other cofactors.
Topics: Fabaceae; Folic Acid; Glycine; Humans; Serine | 1954 |
Interrelationship of serine and glycine for chick growth.
Topics: Animals; Chickens; Fabaceae; Glycine; Meat; Poultry; Serine | 1955 |
Metabolism of serine and glycine peptides by mutents of Escherichia coli strain K-12.
Topics: Escherichia coli; Glycine; Peptides; Serine | 1955 |
The interconversion of serine and glycine: participation of pyridoxal phosphate.
Topics: Coenzymes; Fabaceae; Glycine; Pyridoxal Phosphate; Serine | 1955 |
Amino acid composition and electrophoretic properties of hypertensin I.
Topics: Amino Acids; Angiotensin Amide; Angiotensins; Arginine; Aspartic Acid; Glycine; Histidine; Isoleucine; Leucine; Phenylalanine; Proline; Serine; Tyrosine; Valine | 1955 |
The biosynthesis of free glycine and serine by tumors.
Topics: Glycine; Humans; Neoplasms; Serine | 1955 |
A comparison of alanine and glucose as precursors of serine and glycine.
Topics: Alanine; Carbohydrate Metabolism; Glucose; Glycine; Serine | 1956 |
The rôle of polyglutamyl pteridine coenzymes in serine metabolism. I. Cofactor requirements in the conversion of serine to glycine.
Topics: Coenzymes; Fabaceae; Glutamates; Glycine; Organic Chemicals; Pteridines; Serine | 1956 |
The rôle of polyglutamyl pteridine coenzymes in serine metabolism. II. A comparison of various pteridine derivatives.
Topics: Coenzymes; Glutamates; Glycine; Pteridines; Serine | 1956 |
Glycerol metabolism of normal and malignant lymphatic tissue; the preferential labeling of tumor serine and glycine.
Topics: Glycerol; Glycine; Humans; Lymphatic System; Lymphoid Tissue; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms; Serine | 1956 |
The interconversion of serine and glycine; preparation and properties of catalytic derivatives of pteroylglutamic acid.
Topics: Catalysis; Coenzymes; Fabaceae; Folic Acid; Glycine; Humans; Liver; Serine | 1957 |
The interconversion of serine and glycine; some further properties of the enzyme system.
Topics: Coenzymes; Fabaceae; Folic Acid; Glycine; Humans; Liver; Serine | 1957 |
The nutrition of animal tissues cultivated in vitro. IV. Amino acid requirements of chick embryonic heart fibroblasts.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Fibroblasts; Glycine; Histidine; Hydroxyproline; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
The amino acid requirements of rabbit fibroblasts, strain RM3-56.
Topics: Alanine; Amino Acids; Animals; Arginine; Cystine; Fibroblasts; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Rabbits; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
The formation of glycine and serine; the influence of the administration of glycine, DL-serine and other compounds on levels of tissue glycine and serine.
Topics: Amino Acids; Fabaceae; Glycine; Serine | 1957 |
The absorption of glycine and its conversion to serine in patients with sprue.
Topics: Celiac Disease; Glycine; Humans; Serine | 1958 |
Metabolism of glycine and serine in Escherichia coli.
Topics: Escherichia coli; Glycine; Serine | 1957 |
The formation of glycine and serine: calculation of certain reaction rates in the rat.
Topics: Animals; Biochemical Phenomena; Glycine; Rats; Serine | 1958 |
Serine-glycine interconversion in plant tissues.
Topics: Glycine; Plants; Serine | 1958 |
Studies on wheat plants using carbon-14 compounds. IX. Radioactivity of wheat following injection of formate-C14 and glycine-1-C14 with special reference to serine labelling.
Topics: Carbon Radioisotopes; Dietary Fats, Unsaturated; Fabaceae; Formates; Glycine; Radioactivity; Serine; Triticum | 1959 |
The interconversion of glycine and serine in Zea mays.
Topics: Biochemical Phenomena; Fabaceae; Glycine; Humans; Serine; Zea mays | 1959 |
Inter-relationships of serine, glycine and vitamin B6 in the growth of mutants of Escherichia coli.
Topics: Biochemical Phenomena; Biological Phenomena; Escherichia coli; Fabaceae; Glycine; Physiological Phenomena; Serine; Vitamin B 6 | 1959 |
Enzyme biosynthesis in Escherichia coli.
Topics: beta-Galactosidase; Enzymes; Escherichia coli; Glycine; Serine | 1959 |
Metabolite uptake by serineglycine auxotrophs of Escherichia coli.
Topics: Escherichia coli; Glycine; Serine | 1960 |
Contributions to silkworm biochemistry. VIII. Conversion of pyruvate into alanine, glycine and serine of silkfibroin.
Topics: Alanine; Animals; Bombyx; Fabaceae; Glycine; Proteins; Pyruvates; Pyruvic Acid; Serine | 1959 |
[Contributions to silkworm biochemistry. XVI. Conversion of threonine into the glycine, serine and alanine of silk fibroin].
Topics: Alanine; Amino Acids; Animals; Bombyx; Fibroins; Glycine; Insecta; Proteins; Serine; Silk; Threonine | 1960 |
The influence of folic acid, threonine and glycine on serine synthesis in Tetrahymena.
Topics: Amino Acids; Folic Acid; Glycine; Humans; Serine; Tetrahymena; Threonine | 1960 |
Influence of dietary glycine and serine on lipid metabolism in the rat in folic acid deficiency.
Topics: Animals; Diet; Folic Acid; Folic Acid Deficiency; Glycine; Lipid Metabolism; Lipids; Nutrition Assessment; Nutritional Status; Rats; Serine | 1960 |
Endogenous oxalate synthesis and glycine, serine, deoxypyridoxine interrelationships in vitamin B6-deficient rats.
Topics: Animals; Glycine; Oxalates; Rats; Serine; Vitamin B 6; Vitamin B 6 Deficiency | 1959 |
Conversion of the N-terminal serine residue of corticotrophin into glycine.
Topics: Adrenocorticotropic Hormone; Glycine; Serine | 1962 |
Effect of cultural conditions on growth and metabolite uptake by serine-glycine auxotrophs of Escherichia coli.
Topics: Amino Acids; Asparagine; Biological Transport; Escherichia coli; Glycine; Homoserine; Serine; Threonine | 1962 |
Further studies on metabolite uptake by serine-glycine auxotrophs of Escherichia coli.
Topics: Escherichia coli; Glycine; Serine | 1962 |
Amino acids, amino sugars and sugars present in the cell wall of some strains of Streptococcus pyogenes.
Topics: Alanine; Amino Acids; Amino Sugars; Arginine; Aspartic Acid; Cell Wall; Cysteine; Glucosamine; Glutamates; Glycine; Hexosamines; Isoleucine; Leucine; Lysine; Serine; Streptococcus pyogenes; Threonine; Valine | 1962 |
Formiminoglutamicaciduria in humans with megaloblastic anemia: diminution by methionine or glycine.
Topics: Amino Acids; Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Glutamates; Glycine; Methionine; Serine | 1963 |
[On amino acid metabolism in blood diseases with special reference to aplastic anemia].
Topics: Alanine; Amino Acids; Anemia; Anemia, Aplastic; Glutamates; Glycine; Humans; Hydroxyproline; Serine; Threonine | 1962 |
Some characteristics of the steroid-sensitive amino acid incorporating system of mouse kidney.
Topics: Amino Acids; Glycine; Hydrocortisone; Kidney; Leucine; Methionine; Phenylalanine; Serine; Testosterone; Valine | 1963 |
Amino acid cross resistance in Agrobacterium tumefaciens.
Topics: Agrobacterium; Agrobacterium tumefaciens; Amino Acids; Glycine; Leucine; Methionine; Rhizobium; Serine; Valine | 1962 |
Nematode biochemistry. II. Biosynthesis of amino acids.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Nematoda; Serine; Threonine; Tyrosine; Valine | 1962 |
Mechanism of action of O-carbamyl-D-serine, a new member of cell wall synthesis inhibitors.
Topics: Alanine; Anti-Bacterial Agents; Antibiotics, Antitubercular; Bacillus subtilis; Cell Wall; Dermatologic Agents; Glutamates; Glutamine; Glycine; Penicillin G; Serine; Staphylococcus | 1963 |
[Thin layer chromatographic separation of amino acids on cellulose layers].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Methionine; Serine; Tryptophan; Tyrosine; Valine | 1962 |
[Contributions to the biochemistry of the silk-worm. XXVI. Utilization of glucose for the synthesis of fibroin by Bombyx mori I].
Topics: Alanine; Animals; Aspartic Acid; Bombyx; Fibroins; Glucose; Glutamates; Glycine; Helminthiasis; Helminths; Pyruvates; Serine; Silk | 1962 |
Effect of certain factors on nitrogen retention and lysine requirements of adult human subjects. III. Source of supplementary nitrogen.
Topics: Adult; Ammonium Compounds; Diet; Glutamates; Glycine; Humans; Lysine; Nitrogen; Quaternary Ammonium Compounds; Serine | 1963 |
THE LEVELS OF FREE ASPARTIC ACID, GLYCINE, AND SERINE IN TISSUES OF BONE MARROW CHIMERAS.
Topics: Animals; Aspartic Acid; Bone Marrow; Bone Marrow Transplantation; Chimera; Glycine; Mice; Radiation Effects; Research; Serine | 1963 |
VARIATION OF FREE AMINO ACIDS IN CORCYRA CEPHALONICA ST. (RICE MOTH LARVAE) DURING SOME B VITAMIN DEFICIENCIES.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Chromatography; Glutamates; Glycine; Insecta; Larva; Leucine; Moths; Niacin; Phenylalanine; Research; Riboflavin Deficiency; Serine; Thiamine Deficiency; Tyrosine; Valine; Vitamin B 6 Deficiency; Vitamin B Deficiency | 1963 |
BIOSYNTHESIS OF SERINE IN ESCHERICHIA COLI AND SALMONELLA TYPHIMURIUM.
Topics: Alanine; Autoradiography; Carbon Isotopes; Chromatography; Escherichia coli; Glucose; Glyceric Acids; Glycerophosphates; Glycine; Ketoglutaric Acids; Metabolism; NAD; Oxidoreductases; Phosphoric Monoester Hydrolases; Pyruvates; Research; Salmonella typhimurium; Serine; Valine | 1963 |
[MECHANISMS OF AMINO ACID SYNTHESIS IN LEAVES. STUDIES USING RADIOCARBON].
Topics: Alanine; Amino Acids; Aminobutyrates; Ammonium Compounds; Asparagine; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Chromatography; Darkness; Glutamates; Glutamine; Glycine; Light; Methionine; Nitrates; Plant Proteins; Proteins; Quaternary Ammonium Compounds; Research; Serine; Threonine | 1963 |
COMPARATIVE BIOCHEMISTRY OF HEPATOMAS. V. STUDIES ON AMINO ACID INCORPORATION IN LIVER TUMORS OF DIFFERENT GROWTH RATES.
Topics: Alanine; Amino Acids; Aspartic Acid; Carcinoma, Hepatocellular; Glycine; Histocytochemistry; Isoleucine; Liver Neoplasms; Liver Regeneration; Mice; Neoplasms, Experimental; Proteins; Research; Serine; Valine | 1963 |
THE ASSIMILATION OF 2-C COMPOUNDS OTHER THAN ACETATE.
Topics: Acetates; Arthrobacter; Aspartic Acid; Citric Acid Cycle; Clostridium; Escherichia coli; Glycine; Glycolates; Keto Acids; Metabolism; Micrococcus; Oxalates; Peptococcus; Propionates; Pseudomonas; Pyruvates; Serine; Tartronates | 1963 |
STUDIES ON COLLETOTRICHUM CAPSICI III. THE EFFECT OF INITIAL PH ON THE GROWTH AND AMINO ACID COMPOSITION.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Chromatography; Colletotrichum; Cysteine; Fungi; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Phenylalanine; Research; Serine; Tyrosine | 1963 |
A NEW CLASS OF BLOOD COAGULATION INHIBITORS.
Topics: Animals; Anticoagulants; Arginine; Blood Chemical Analysis; Blood Coagulation; Crustacea; Dipeptides; Fibrin; Glycine; Hydroxylamines; Pharmacology; Rats; Research; Serine | 1963 |
SPECIFICITY OF PEPSIN AND ITS DEPENDENCE ON A POSSIBLE 'HYDROPHOBICBINDING SITE'.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pepsin A; Peptides; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
GAS CHROMATOGRAPHY OF AMINO ACIDS. 1. ANALYSIS OF THE MIXTURE OF METHYL-NTRIFLUOROACETYL DERIVATIVES.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography; Chromatography, Gas; Fluoroacetates; Glutamates; Glycine; Hydroxyproline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1963 |
THE EFFECT OF ETHANOL AND ELECTRICAL STIMULATION ON THE AMINO ACID METABOLISM OF RAT-BRAIN-CORTEX SLICES IN VITRO.
Topics: Alanine; Alcoholic Intoxication; Amino Acids; Aminobutyrates; Ammonium Chloride; Aspartic Acid; Brain; Carbon Isotopes; Cerebral Cortex; Electric Stimulation; Electrophysiology; Ethanol; Glutamates; Glutamine; Glycine; In Vitro Techniques; Proteins; Rats; Research; Serine; Taurine; Toxicology | 1963 |
EFFECT OF ENVIRONMENTAL CONDITIONS ON THE NADP-SPECIFIC GLUTAMIC ACID DEHYDROGENASE IN NEUROSPORA CRASSA.
Topics: Amino Acid Oxidoreductases; Ammonium Compounds; Caseins; Glutamates; Glycine; Lysine; NADP; Neurospora; Neurospora crassa; Pharmacology; Proteins; Quaternary Ammonium Compounds; Research; Serine | 1963 |
THE AMINO ACID CODE AND BIOSYNTHESIS OF THE SILK.
Topics: Adenine Nucleotides; Amino Acids; Animals; Bombyx; Carbon Isotopes; Escherichia coli; Fibroins; Glutamates; Glycine; Guanine Nucleotides; Leucine; Phosphorus Isotopes; Proteins; Research; RNA; Serine; Silk; Uracil Nucleotides; Valine | 1963 |
MECHANISM OF ACTION OF O-CARBAMYL-D-SERINE.
Topics: Alanine; Anti-Bacterial Agents; Bacillus subtilis; Carbohydrate Metabolism; Escherichia coli; Glutamates; Glycine; Lysine; Pharmacology; Purines; Research; Serine; Staphylococcus | 1963 |
EFFECT OF ALANINE AND THREONINE ON THE SYNTHESIS OF SERINE BY LEUCONOSTOC MESENTEROIDES.
Topics: Alanine; Amino Acids; Bacterial Proteins; Benzoates; Formates; Glutamine; Glycine; Histidine; Leuconostoc; Leucovorin; Proteins; Research; Serine; Threonine | 1963 |
OXIDATION OF L-AMINO ACIDS AND INCORPORATION INTO PROTEIN IN HOMOGENATES OF BRAIN AT TWO STAGES OF DEVELOPMENT.
Topics: Alanine; Amino Acids; Arginine; Autoradiography; Brain; Carbon Isotopes; Chromatography; Glycine; Histidine; Isoleucine; Keto Acids; Leucine; Lysine; Mice; Nerve Tissue Proteins; Phenylalanine; Proline; Proteins; Pyruvates; Research; Serine; Threonine; Valine | 1963 |
THE RELATION OF SERINE--GLYCINE METABOLISM TO THE FORMATION OF SINGLE-CARBON UNITS.
Topics: Antimetabolites; Carbon; Carbon Isotopes; Culture Media; Escherichia coli; Formates; Glycine; Mutation; Pharmacology; Proteins; Research; Serine; Xanthines | 1963 |
THE BIOSYNTHESIS OF SERINE IN BAKER'S YEAST.
Topics: Acetates; Antimetabolites; Carbon Isotopes; Chromatography; Citric Acid Cycle; Formates; Glycine; Pharmacology; Proteins; Pyruvates; Research; Saccharomyces; Saccharomyces cerevisiae; Serine | 1963 |
[CONTRIBUTION TO THE STUDY OF RIBONUCLEOPROTEINS OF NORMAL AND NEOPLASTIC TISSUES].
Topics: Alanine; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glycine; Isoleucine; Leucine; Liver; Lysine; Mice; Neoplasm Proteins; Neoplasms; Nucleoproteins; Phenylalanine; Rats; Research; Ribonucleoproteins; RNA; RNA, Neoplasm; Serine; Threonine; Tyrosine; Valine | 1963 |
THE BIOSYNTHESIS OF THIAMINE. V. STUDIES CONCERNING PRECURSORS OF THE PYRIMIDINE MOIETY.
Topics: Acetates; Aspartic Acid; Carbon Isotopes; Chromatography; Escherichia coli; Formates; Glycine; Ion Exchange Resins; Metabolism; Methionine; Orotic Acid; Pyrimidines; Research; Serine; Sulfonic Acids; Thiamine; Uracil | 1963 |
[SOME METABOLIC ASPECTS OF RENAL LITHIASIS].
Topics: Calcium; Calcium, Dietary; Carbohydrate Metabolism; Glycine; Humans; Lithiasis; Mexico; Minerals; Nephrolithiasis; Oxalates; Pathology; Proteins; Serine; Uric Acid; Urinary Calculi | 1963 |
GREEN FLUORESCENT PIGMENT ACCUMULATED BY A MUTANT OF CELLVIBRIO GILVUS.
Topics: Amino Acids; Bacteria; Carbon Isotopes; Cellvibrio; Chromatography; Culture Media; Fluorescence; Glucose; Glycine; Levulinic Acids; Lysine; Phenylalanine; Pigments, Biological; Proline; Research; Serine | 1964 |
BIOCHEMISTRY OF LUNGS IN RELATION TO SILICOSIS. II. THE EFFECT OF QUARTZ DUST ON THE PROTEIN AMINO ACIDS OF GUINEA PIG LUNG TISSUE.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Collagen; Cystine; Dust; Glutamates; Glycine; Guinea Pigs; Histidine; Hydroxyproline; Isoleucine; Leucine; Lung; Lysine; Methionine; Phenylalanine; Proline; Quartz; Research; Serine; Silicon Dioxide; Silicosis; Threonine; Toxicology; Tyrosine; Valine | 1964 |
RELATIVE POTENCY OF DIETS CONTAINING AMINO ACIDS AND PROTEINS FOR PROMOTING GROWTH OF RATS.
Topics: Albumins; Amino Acids; Animals, Newborn; Arginine; Cystine; Diet; Dietary Proteins; Glutamates; Glycine; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Proteins; Rats; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
ASPECTS OF CHEMORECEPTION IN CRUSTACEA.
Topics: Aminobutyrates; Animals; Aspartic Acid; Crustacea; Cysteine; Electrophysiology; Glutamates; Glutathione; Glycine; Glycogen; Histamine; Indoles; Leucine; Methionine; Muscles; Pharmacology; Research; Sensory Receptor Cells; Serine; Tyrosine; Urea | 1963 |
[CONTRIBUTION TO THE STUDY OF EXPERIMENTAL HEPATIC UREOGENESIS].
Topics: Alanine; Dogs; Glycine; Liver; Proteins; Research; Serine; Urea | 1963 |
THE CHEMICAL COMPOSITION OF THE CELL WALL OF THE YEAST, NADSONIA ELONGATA.
Topics: Aspartic Acid; Carbohydrates; Carbon Isotopes; Cell Biology; Cell Wall; Centrifugation; Chemical Phenomena; Chemistry; Chromatography; Fatty Acids; Glucosamine; Glycine; Mannose; Nitrogen; Phosphorus; Plant Proteins; Research; Serine; Sodium Chloride; Threonine; Yeasts | 1964 |
THE INCORPORATION OF LABELLED CO2 INTO CELLS AND EXTRACTS OF NITROSOMONAS EUROPAEA.
Topics: Adenosine Triphosphate; Alanine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Glycine; Heptoses; Hexoses; Metabolism; NAD; Nitrosomonas; Nitrosomonas europaea; Phosphates; Pyruvates; Research; Serine; Threonine | 1964 |
[BACTERIOSTATIC EFFECT OF VARIOUS AMINOACID ESTERS].
Topics: Amino Acids; Bacteria; Cystine; Esters; Glutamates; Glycine; Leucine; Lysine; Pharmacology; Serine; Tryptophan | 1963 |
SOME CHARACTERISTICS OF THE SHEEP THYROID GLAND SYSTEM FOR INCORPORATING AMINO ACIDS INTO PROTEIN.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Glucose; Glutamates; Glycine; Ketoglutaric Acids; Leucine; Phenylalanine; Physiology; Proteins; Pyruvates; Research; Serine; Sheep; Succinates; Thyroid Gland; Thyrotropin; Tyrosine; Valine | 1964 |
TRANSFORMATION OF BACILLUS LICHENIFORMIS.
Topics: Bacillus; Bacillus subtilis; DNA; DNA, Bacterial; Glycine; Histidine; Mutation; Oregon; Research; Serine; Tryptophan | 1964 |
NITROGEN BALANCES FOR YOUNG ADULT MALES FED TWO SOURCES OF NONESSENTIAL NITROGEN AT TWO LEVELS OF TOTAL NITROGEN INTAKE.
Topics: Alanine; Ammonium Compounds; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Male; Nitrogen; Nitrogen Fixation; Proline; Proteins; Quaternary Ammonium Compounds; Serine | 1964 |
FREE AMINO ACIDS IN PLASMA AND TISSUES OF RATS FED A VITAMIN B6-DEFICIENT DIET.
Topics: Alanine; Amino Acids; Aspartic Acid; Blood; Diet; Glycine; Liver; Muscles; Proteins; Rats; Research; Serine; Vitamin B 6; Vitamin B 6 Deficiency | 1964 |
[EFFECTS OF HYDROXYLAMINE ON ESCHERICHIA COLI BIOSYNTHESIS].
Topics: Aspartic Acid; Escherichia coli; Glycine; Hydroxylamine; Hydroxylamines; Lysine; Pharmacology; Phenylalanine; Proline; Proteins; Research; Serine | 1964 |
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
[RESEARCH ON THE MECHANISM OF SYNTHESIS OF THE AMINO ACIDS IN PLANTS (CHLORELLA VULGARIS). III. CHANGES INDUCED BY THE INTERRUPTION OF ILLUMINATION].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Carbon Isotopes; Chlorella vulgaris; Eukaryota; Glutamates; Glycine; Lighting; Lysine; Proteins; Research; Serine | 1964 |
THE ROLE OF DISPENSABLE AMINO ACIDS IN THE NUTRITION OF THE RAT.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bicarbonates; Caseins; Cystine; Dietary Proteins; Glutamates; Glycine; Growth; Histidine; Isoleucine; Lysine; Methionine; Phenylalanine; Proline; Proteins; Rats; Research; Serine; Tyrosine | 1964 |
THE CONTENT OF AMINO ACIDS IN THE PROTEINS OF THE DEVELOPING NERVOUS SYSTEM OF THE GUINEA PIG. III. SPINAL CORD.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; Cystine; Fetus; Glutamates; Glycine; Guinea Pigs; Histidine; Leucine; Lysine; Nerve Tissue Proteins; Nervous System; Phenylalanine; Research; Serine; Spinal Cord; Threonine; Tyrosine; Valine | 1964 |
POLYNUCLEOTIDE ANALOGUES. II. STIMULATION OF AMINO ACID INCORPORATION BY POLYNUCLEOTIDE ANALOGUES.
Topics: Amino Acids; Carbon Isotopes; Chromatography; Cysteine; Escherichia coli; Glycine; Isoleucine; Leucine; Lysine; Pharmacology; Phenylalanine; Polynucleotides; Proline; Proteins; Research; Serine; Threonine; Tryptophan; Tyrosine; Uracil Nucleotides; Valine | 1964 |
THE INFLUENCE OF GLUCOSE ON AMINO ACID CARBON INCORPORATION INTO PROTEINS, FATTY ACIDS, AND CARBON DIOXIDE BY LACTATING RAT MAMMARY GLAND SLICES.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon; Carbon Dioxide; Carbon Isotopes; Chromatography; Fatty Acids; Female; Glucose; Glutamates; Glycine; Humans; Lactation; Leucine; Lipid Metabolism; Lysine; Mammary Glands, Animal; Mammary Glands, Human; Methionine; Phenylalanine; Proteins; Rats; Research; Serine | 1964 |
MIGRATION OF AMINO ACIDS ACROSS THE MEMBRANE OF THE HUMAN ERYTHROCYTE.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport; Carbon Isotopes; Erythrocytes; Glycine; Histidine; Leucine; Methionine; Permeability; Phenylalanine; Proteins; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
IDIOPATHIC HYPERGLYCINEMIA; A POSSIBILITY OF HETEROZYGOSITY IN THE PARENTS.
Topics: Amino Acid Metabolism, Inborn Errors; Blood; Body Fluids; Genetics, Medical; Glycine; Humans; Infant; Parents; Proteins; Serine; Urine | 1964 |
DYNAMIC PHENOMENA IN MICROSPHERES FROM THERMAL PROTEINOID.
Topics: Alanine; Arginine; Aspartic Acid; Colloids; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Microspheres; Peptides; Phenylalanine; Photomicrography; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
[SEPARATION OF AMINO ACIDS BY CHROMATOGRAPHY ON THIN LAYERS OF DIETHYLAMINOETHYL CELLULOSE].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
URIDINE-BOUND PEPTIDES IN CHLORELLAVULGARIS.
Topics: Arginine; Chromatography; Cystine; Electrophoresis; Eukaryota; Glutamates; Glycine; Hydroxamic Acids; Methionine; Nucleosides; Peptides; Research; Serine; Sulfur Isotopes; Ultraviolet Rays; Uridine | 1964 |
[PHARMACEUTICAL AND CHEMICAL STUDIES ON INSULIN. (31) ON N- AND C-TERMINAL AMINO ACIDS OF CRYSTAL TA].
Topics: Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Fishes; Glycine; Insulin; Isoleucine; Lysine; Research; Serine; Valine | 1963 |
FORMATION OF LACTIC ACID FROM GLYCINE BY CATTLE LENS.
Topics: Animals; Autoradiography; Carbon Isotopes; Cattle; Chromatography; Coenzyme A; Glycine; Lactates; Lactic Acid; Lens, Crystalline; Metabolism; Research; Serine | 1964 |
ELECTROENCEPHALOGRAMS OF SHARKS.
Topics: Animals; Brain; Cerebellum; Crustacea; Cysteine; Diencephalon; Electroencephalography; Electrophysiology; Glutamates; Glycine; Light; Limbic System; Medulla Oblongata; Mesencephalon; Research; Serine; Sharks; Telencephalon; Tissue Extracts | 1964 |
THE INHIBITION OF MITOCHONDRIAL ADENOSINE TRIPHOSPHATASE. 2. THE EFFECTS OF AMINO ACIDS AND SUGARS.
Topics: Adenosine Triphosphatases; Alanine; Amino Acids; Arabinose; Arginine; Aspartic Acid; Enzyme Inhibitors; Fructose; Glutamates; Glycine; Histidine; Hydroxyproline; Isoleucine; Lactose; Liver; Lysine; Methionine; Mitochondria; Oligosaccharides; Pharmacology; Proline; Rats; Research; Serine; Threonine; Valine | 1964 |
AMINO ACID METABOLISM IN RAT BRAIN STUDIED WITH 14C-LABELLED GLUCOSE.
Topics: Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Brain; Carbon Isotopes; Glucose; Glutamates; Glutamine; Glycine; Lead; Nitrophenols; Proteins; Rats; Research; Seizures; Serine; Threonine; Tin; Toxicology | 1964 |
GLYCYLGLYCINE UPTAKE IN STREPTOCOCCI AND A POSSIBLE ROLE OF PEPTIDES IN AMINO ACID TRANSPORT.
Topics: Alanine; Amino Acids; Biological Transport; Carbon Isotopes; Dinitrophenols; Enterococcus faecalis; Glycine; Glycylglycine; Novobiocin; Peptides; Pharmacology; Proteins; Research; Serine | 1964 |
CHROMATOGRAPHIC SEPARATION OF PYRIDOXYL DERIVATIVES OF AMINO ACIDS.
Topics: Alanine; Amines; Amino Acids; Arginine; Aspartic Acid; Chromatography; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Phenylalanine; Pyridines; Pyridoxine; Research; Serine; Threonine; Tyrosine; Valine | 1964 |
THE ELECTRON MICROSCOPIC LOCALIZATION OF THE NEUTRAL SOLUBLE PROTEINS OF DEVELOPING BOVINE ENAMEL.
Topics: Amino Acids; Animals; Cattle; Dental Calculus; Dental Enamel; Electrons; Embryology; Glutamine; Glycine; Histidine; Histocytochemistry; Microscopy; Microscopy, Electron; Proline; Proteins; Research; Serine | 1964 |
PLASMA AMINO ACID PATTERNS IN ALCOHOLISM: THE EFFECTS OF ETHANOL LOADING.
Topics: Alanine; Alcoholism; Amino Acids; Autoanalysis; Biomedical Research; Blood; Ethanol; Genetics, Medical; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Methionine; NAD; NADP; Proline; Proteins; Serine; Toxicology; Valine | 1964 |
SERUM AMINO ACIDS IN KWASHIORKOR. I. RELATIONSHIP TO CLINICAL CONDITION.
Topics: Alanine; Amino Acids; Biomedical Research; Black People; Blood; Glutamates; Glutamine; Glycine; Infant; Isoleucine; Kwashiorkor; Leucine; Methionine; Phenylalanine; Serine; Threonine; Tyrosine; Uganda; Valine | 1964 |
A MULTIVARIATE ANALYSIS OF AMINO-ACID EXCRETIONS.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Biomedical Research; Child; Chromatography; Electronic Data Processing; Glutamine; Glycine; Humans; Intellectual Disability; Multivariate Analysis; Renal Aminoacidurias; Serine; Taurine | 1964 |
[FREE AMINO ACIDS IN THE BLOOD AND URINE OF PATIENTS WITH SOME FORMS OF DERMATOSIS].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Blood; Cystine; Dermatitis; Eczema; Erythema Multiforme; Glutamates; Glycine; Histidine; Lupus Erythematosus, Systemic; Lysine; Proteins; Psoriasis; Renal Aminoacidurias; Serine; Skin Diseases; Taurine; Threonine; Toxicology; Tryptophan; Urticaria | 1964 |
A SIMPLE PREPARATION METHOD FOR DIPHOSPHOMIDAZOLE.
Topics: Alanine; Amides; Calcium Phosphates; Chlorides; Chromatography; Cysteine; Cystine; Glycine; Histidine; Imidazoles; Ion Exchange Resins; Methionine; Phosphates; Phosphorus; Research; Serine; Tryptophan; Tyrosine | 1964 |
NUTRITIONAL FACTORS RELATING TO GROWTH AND OXYTETRACYCLINE FORMATION BY STREPTOMYCES RIMOSUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Culture Media; Cysteine; Cystine; Glutamine; Glycine; Histidine; Isoleucine; Lysine; Metabolism; Methionine; Oxytetracycline; Research; Serine; Streptomyces; Streptomyces rimosus | 1964 |
GLYCINE-SPECIFIC TRANSFER RIBONUCLEIC ACID IN THE POSTERIOR SILKGLAND OF BOMBYX MORI.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Bombyx; Carbon Isotopes; Fibroins; Glutamates; Glycine; Research; RNA; RNA, Transfer; Serine | 1964 |
INOTROPIC ACTIVITY OF A SERIES OF AMINO ACIDS.
Topics: Adrenal Glands; Alanine; Amino Acids; Blood Pressure; Cysteine; Dogs; Glycine; Heart; Leucine; Methionine; Pharmacology; Research; Sensory Receptor Cells; Serine; Threonine | 1964 |
[FREE PLASMA AMINO ACIDS IN LIVER CIRRHOSIS AND HEPATITIS].
Topics: Alanine; Amino Acids; Blood; Chromatography; Glutamine; Glycine; Hepatitis; Humans; Ion Exchange Resins; Liver Cirrhosis; Methionine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine | 1964 |
A COMPARISON OF (14C)GLYOXYLATE AND (14C)ACETATE METABOLISM IN GERMINATING FATTY SEEDS.
Topics: Acetates; Alanine; Aspartic Acid; Carbohydrate Metabolism; Carbon Dioxide; Carbon Isotopes; Citrates; Flax; Glutamates; Glutamine; Glycine; Glyoxylates; Lipids; Malates; Oxalates; Plants, Edible; Research; Ricinus; Seeds; Serine; Succinates | 1964 |
MYOGLOBIN FREE-RADICALS.
Topics: Alanine; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Glycine; Histidine; Hydrogen Peroxide; Leucine; Myoglobin; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
[CELL CULTIVATION IN PROTEIN-FREE CULTURE MEDIA. 1. CELL STRAIN L (EARLE): GROWTH AND CHROMOSOMES].
Topics: Animals; Chromosomes; Clone Cells; Culture Media; Culture Media, Serum-Free; Dextrans; Glycine; L Cells; Mice; Proteins; Research; Serine; Tissue Culture Techniques | 1964 |
NUTRITIONAL AND REGULATORY ASPECTS OF SERINE METABOLISM IN ESCHERICHIA COLI.
Topics: Adenine Nucleotides; Amino Acids; Carbohydrate Metabolism; Carbon Isotopes; Escherichia coli; Fructose; Glucose; Glycerolphosphate Dehydrogenase; Glycine; Guanine Nucleotides; Isoleucine; Lactates; Leucine; Metabolism; Methionine; Phosphates; Phosphoric Monoester Hydrolases; Research; Serine; Threonine | 1964 |
SOME PROPERTIES OF METHANOBACTERIUM OMELIANSKII FERREDOXIN.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacteria; Chemistry Techniques, Analytical; Cystine; Ferredoxins; Glutamates; Glycine; Iron; Lysine; Methanobacterium; Proline; Serine; Spectrophotometry; Sulfides; Threonine; Tyrosine; Valine | 1964 |
LIQUID-LIQUID EXTRACTION IN THE AUTOANALYZER. DETERMINATION OF TAURINE.
Topics: Adrenalectomy; Alanine; Autoanalysis; Automation; Chemistry Techniques, Analytical; Chloroform; Glycine; Liquid-Liquid Extraction; Rats; Research; Serine; Sulfonic Acids; Taurine; Threonine | 1964 |
CLUSTERING OF FUNCTIONALLY RELATED GENES IN SALMONELLA TYPHIMURIUM.
Topics: Arginine; Cysteine; Escherichia coli; Glycine; Guanine; Histidine; Isoleucine; Leucine; Metabolism; Methionine; Molecular Biology; Mutation; Pantothenic Acid; Proline; Purines; Pyrimidines; Research; Salmonella typhimurium; Serine; Threonine; Tryptophan | 1964 |
SOME IN VITRO STUDIES OF POLONIUM-210 BINDING BY BLOOD CONSTITUENTS.
Topics: Amino Acids; Aspartic Acid; Bicarbonates; Blood; Citrates; Cysteine; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Malates; Metabolism; Phosphates; Polonium; Research; Serine; Tryptophan | 1964 |
STUDIES ON WHEAT PLANTS USING CARBON-14 COMPOUNDS. XXI. THE METABOLISM OF GLYCINE-2-C14.
Topics: Acetates; Amino Acids; Carbon Dioxide; Carbon Isotopes; Carbon Radioisotopes; Fabaceae; Formaldehyde; Glycine; Plant Proteins; Research; Serine; Triticum | 1964 |
IMPROVED TECHNIQUE FOR THE PREPARATION OF STREPTOCOCCAL CELL WALLS.
Topics: Alanine; Amino Sugars; Bacteriological Techniques; Bacteriolysis; Cell Wall; Chemistry Techniques, Analytical; Electrons; Galactose; Glucosamine; Glutamates; Glycine; Lysine; Microscopy; Microscopy, Electron; Research; Rhamnose; Serine; Streptococcus | 1964 |
[A COMPARATIVE STUDY OF THE BIOLOGICAL AND SEROLOGICAL PROPERTIES OF PERTUSSIS AND PARAPERTUSSIS BACTERIA].
Topics: Arginine; Bacteria; Bordetella; Bordetella pertussis; Glutamates; Glycine; Metabolism; Pigments, Biological; Research; Serine; Urease; Whooping Cough | 1964 |
COMPARATIVE RADIOLABILITY OF AMINO ACIDS OF PROTEINS AND FREE AMINO ACIDS.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Catalase; Chromatography; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Ovalbumin; Phenylalanine; Proteins; Radiation Effects; Research; Serine; Valine | 1964 |
BIOSYNTHESIS OF THE PHENYLPROPANOID MOIETY OF CHLORAMPHENICOL.
Topics: Acetates; Chemical Phenomena; Chemistry; Chloramphenicol; Glucose; Glycine; Lactates; Metabolism; Nitrophenols; Phenylalanine; Research; Serine; Shikimic Acid; Streptomyces | 1964 |
CATALYTIC REACTIONS INVOLVING AZOMETHINES. IV. RATES AND EQUILIBRIA OF IMINE FORMATION WITH PYRIDINE-4-ALDEHYDE AND VARIOUS AMINO ACIDS.
Topics: Alanine; Aldehydes; Amino Acids; Arginine; Asparagine; Aspartic Acid; Azo Compounds; Biochemical Phenomena; Biochemistry; Glutamates; Glycine; Imines; Leucine; Phenylalanine; Pyridines; Research; Serine; Spectrophotometry; Thiosemicarbazones; Valine | 1964 |
HYPERGLYCINEMIA. V. THE MISCIBLE POOL AND TURNOVER RATE OF GLYCINE AND THE FORMATION OF SERINE.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Blood; Child; Chromatography; Glycine; Humans; Intellectual Disability; Metabolism, Inborn Errors; Serine; Tritium | 1964 |
PRIMARY PRODUCTS OF PHOTOSYNTHESIS IN LEAVES OF CELERY.
Topics: Alanine; Apium; Carbon Dioxide; Carbon Isotopes; Glycine; Mannitol; Phosphates; Photosynthesis; Plant Leaves; Plants; Plants, Edible; Research; Serine; Sucrose | 1964 |
METABOLISM OF EHRLICH ASCITES CARCINOMA CELLS GROWN IN MICE ON A MEAT DIET.
Topics: Animals; Ascites; Carbon Isotopes; Carcinoma; Carcinoma, Ehrlich Tumor; Diet; Dietary Proteins; Formates; Glycine; Kidney; Liver; Meat; Metabolism; Methionine; Mice; Neoplasm Proteins; Nucleotides; Radiometry; Research; Serine; Spleen | 1964 |
STUDIES ON THE CARBOXYL- AND AMINO-TERMINAL RESIDUES OF RABBIT MUSCLE ALDOLASE.
Topics: Amino Acids; Animals; Carboxypeptidases; Chemical Phenomena; Chemistry; Fructose-Bisphosphate Aldolase; Glycine; Hydrazines; Models, Theoretical; Muscles; Peptides; Rabbits; Research; Serine | 1964 |
[DEGRADATION OF TRYPTOPHAN BY ESCHERICHIA COLI. II. INDIRECT METHODS].
Topics: Alanine; Escherichia coli; Glycine; Indoleacetic Acids; Indoles; Metabolism; Research; Serine; Tryptophan | 1964 |
DILUTE ACID HYDROLYSIS OF PAPAIN. KINETIC STUDIES AND PEPTIDES FROM THE CARBOXYMETHYLATED PROTEIN.
Topics: Alanine; Aspartic Acid; Chromatography; Electrophoresis; Glutamates; Glycine; Hydrolysis; Kinetics; Papain; Peptides; Proteins; Research; Serine; Spectrophotometry; Threonine | 1965 |
[NEOGLUCOGENESIS IN HEPATOCYTES CULTIVATED IN VITRO].
Topics: Alanine; Animals; Carbohydrate Metabolism; Chick Embryo; Cystine; Fibroblasts; Glucose; Glycine; Hepatocytes; In Vitro Techniques; Insulin; Liver; Liver Glycogen; Research; Serine; Tissue Culture Techniques | 1964 |
HYDROGEN EXCHANGE AT CARBON-HYDROGEN SITES DURING ACID OR ALKALINE TREATMENT OF PROTEINS.
Topics: Amino Acids; Aspartic Acid; Carbon; Chemical Phenomena; Chemistry; Chromatography; Cystine; Glycine; Hydrogen; Insulin; Keratins; Muramidase; Proteins; Radiometry; Research; Ribonucleases; Serine; Threonine; Tritium | 1964 |
THE MAJOR ALKALINE PROTEINASE OF ASPERGILLUS ORYZAE, ASPERGILLOPEPTIDASE B. II. PARTIAL SPECIFIC VOLUME, MOLECULAR WEIGHT, AND AMINO ACID COMPOSITION.
Topics: Alanine; Amides; Amino Acids; Aspergillus; Aspergillus oryzae; Bacterial Proteins; Buffers; Chemical Phenomena; Chemistry, Physical; Cysteine; Cystine; Densitometry; Endopeptidases; Glycine; Molecular Weight; Nitrogen; Peptide Hydrolases; Research; Serine; Serine Endopeptidases; Tryptophan | 1964 |
AEROBIC DEGRADATION OF CHOLINE. I. FERMENTATION OF CHOLINE BY A MARINE BACTERIUM, ACHROMOBACTER CHOLINOPHAGUM N. SP.
Topics: Achromobacter; Ammonia; Carbon; Chemical Phenomena; Chemistry; Choline; Chromatography; Fabaceae; Fermentation; Formaldehyde; Glycine; Hydrogen-Ion Concentration; Metabolism; Nitrogen; Pyruvates; Research; Serine | 1964 |
MUTATIONALLY INDUCED AMINO ACID SUBSTITUTIONS IN A TRYPTIC PEPTIDE OF THE TRYPTOPHAN SYNTHETASE A PROTEIN.
Topics: Alanine; Amino Acid Substitution; Amino Acids; Aspartic Acid; Autoanalysis; Bacterial Proteins; Biochemical Phenomena; Biochemistry; Carboxypeptidases; Chromatography; Chromosome Mapping; Chymotrypsin; Escherichia coli; Genetic Code; Glycine; Hydro-Lyases; Isoleucine; Leucyl Aminopeptidase; Molecular Biology; Mutation; Papain; Peptides; Protein Hydrolysates; Research; Serine; Trypsin; Tryptophan Synthase | 1965 |
GLYCINE SYNTHESIS AND METABOLISM IN ESCHERICHIA COLI.
Topics: Amino Acids; Carbon Isotopes; Escherichia coli; Glyceric Acids; Glycine; Mutation; Research; Serine | 1965 |
CONGENITAL HYPERGLYCINEMIA; DEMONSTRATION OF A MINOR METABOLIC DEFECT IN THE PARENTS.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Autoanalysis; Blood Chemical Analysis; Buffers; Colorimetry; Genetics, Medical; Glycine; Humans; Hydrogen-Ion Concentration; Parents; Serine | 1965 |
GAS CHROMATOGRAPHY OF VOLATILE AMINO ACID DERIVATIVES. I. ALANINE, GLYCINE, VALINE, LEUCINE, ISOLEUCINE, SERINE AND THREONINE.
Topics: Alanine; Arginine; Chromatography; Chromatography, Gas; Equipment and Supplies; Glycine; Isoleucine; Leucine; Research; Serine; Threonine; Valine | 1965 |
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. I. SUSPENSION CELL CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA.
Topics: Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Floxuridine; Fluorouracil; Glycine; Liver Neoplasms; Liver Neoplasms, Experimental; Metabolism; Methotrexate; Mutation; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Pyrimidines; Rats; Research; Serine; Thymidine; Thymidine Kinase; Thymine; Tissue Culture Techniques; Toxicology; Uracil | 1965 |
GLYCINE-SERUM INTERCONVERSION AND COLLAGEN BIOSYNTHESIS IN VIVO. POSSIBLE DIFFERENCE IN THE AMINO ACID SUPPLYING SYSTEM BETWEEN SKIN COLLAGEN AND SERUM ALBUMIN IN GUINEA PIGS.
Topics: Amino Acids; Animals; Chromatography; Collagen; Dinitrophenols; Glycine; Guinea Pigs; Proteins; Research; Serine; Serum Albumin; Skin | 1965 |
THE EFFECT OF VITAMIN B6 DEFICIENCY IN RATS ON THE METABOLISM OF OXALIC ACID PRECURSORS.
Topics: Acetates; Amino Alcohols; Carbon Dioxide; Glucose; Glycine; Glycolates; Glycols; Hippurates; Kidney; Liver; Metabolism; Oxalates; Oxalic Acid; Rats; Research; Serine; Urine; Vitamin B 6 Deficiency | 1965 |
RELATIONSHIP OF PNH3 OF TUBULAR CELLS TO RENAL PRODUCTION OF AMMONIA.
Topics: Acidosis; Alanine; Amino Acids; Ammonia; Ammonium Chloride; Animals; Aspartic Acid; Body Fluids; Dogs; Fluids and Secretions; Glomerular Filtration Rate; Glutamates; Glutaminase; Glutamine; Glycine; Kidney; Kidney Tubules; Lactates; p-Aminohippuric Acid; Physiology; Research; Serine; Urine | 1965 |
RAT LIVER ENZYME DOES NOT ACTIVATE ACETYLAMINO ACIDS.
Topics: Acetates; Adenosine Triphosphate; Alanine; Amino Acids; Arginine; Diphosphates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Liver; Lysine; Methionine; Phenylalanine; Proline; Rats; Research; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
CARBON METABOLISM OF C-14-LABELED AMINO ACIDS IN WHEAT LEAVES. 3. FURTHER STUDIES ON THE ROLE OF SERINE IN GLYCINE METABOLISM.
Topics: Amino Acids; Carbon; Fabaceae; Glycine; Plant Leaves; Serine; Triticum | 1965 |
CARBON METABOLISM OF GLYCINE AND SERINE IN RELATION TO THE SYNTHESIS OF ORGANIC ACIDS AND A GUANINE DERIVATIVE.
Topics: Acids; Amino Acids; Carbon; Glycine; Guanine; Organic Chemicals; Serine; Triticum | 1965 |
EFFECT OF AMINO ACIDS ON GROWTH OF SPHAEROTILUS DISCOPHORUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Bacteriological Techniques; Caseins; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Proline; Research; Serine; Sphaerotilus; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
STUDIES ON HUMAN ANTIBODIES. 3. AMINO ACID COMPOSITION OF FOUR ANTIBODIES FROM ONE INDIVIDUAL.
Topics: Alanine; Amino Acids; Antibodies; Arginine; Aspartic Acid; Chemistry Techniques, Analytical; gamma-Globulins; Glutamates; Glycine; Histidine; Immunochemistry; Immunoglobulins; Isoleucine; Leucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1965 |
AEROBIC DEGRADATION OF CHOLINE. II. SOME PROPERTIES OF WHOLE CELLS AND CELL-FREE EXTRACTS OF ACHROMOBACTER CHOLINOPHAGUM.
Topics: Achromobacter; Ammonia; Betaine; Centrifugation; Chemical Precipitation; Choline; Chromatography; Colorimetry; Formaldehyde; Glycine; Metabolism; Oxygen; Pharmacology; Pyruvates; Research; Serine; Spectrophotometry; Trichloroacetic Acid; Ultrasonics | 1965 |
NEMATODE BIOCHEMISTRY. V. INTERMEDIARY METABOLISM AND AMINO ACID INTERCONVERSIONS IN CAENORHABDITIS BRIGGSAE.
Topics: Acetates; Alanine; Amino Acids; Aminobutyrates; Animals; Asparagine; Aspartic Acid; Bicarbonates; Caenorhabditis; Carbon Dioxide; Chromatography; Formates; Glutamates; Glutamine; Glycine; Malates; Nematoda; Phenylalanine; Research; Serine; Taurine; Tyrosine | 1965 |
CHANGES IN THE NERVE CELL PROTEINS IN DOGS DURING RESUSCITATION FROM THE STATE OF CLINICAL DEATH.
Topics: Alanine; Aminobutyrates; Ammonia; Arginine; Asparagine; Brain Chemistry; Cerebral Cortex; Cystine; Death; Dogs; Glutamates; Glutamine; Glycine; Histidine; Histocytochemistry; Hypothermia; Hypothermia, Induced; Leucine; Lysine; Methionine; Nerve Tissue Proteins; Neurons; Pathology; Phenylalanine; Proteins; Research; Resuscitation; Serine | 1965 |
THE SYNTHESIS OF PHOSVITIN IN VITRO BY SLICES OF LIVER FROM THE LAYING HEN.
Topics: Animals; Carbon Dioxide; Carbonates; Chickens; Estradiol; Estrone; Female; Glutamates; Glycine; Humans; In Vitro Techniques; Kidney; Liver; Muscles; Ovary; Pharmacology; Phosphates; Phosvitin; Poultry; Proteins; Reproduction; Research; Serine; Spleen | 1965 |
THE METABOLISM OF L-SERYLGLYCINE O(35S)-SULPHATE IN THE RAT.
Topics: Chromatography; Dipeptidases; Dipeptides; Glycine; Liver; Metabolism; Phenylurea Compounds; Rats; Research; Serine; Sulfates; Urine | 1965 |
MICROBIAL GROWTH ON C1 COMPOUNDS. SYNTHESIS OF CELL CONSTITUENTS BY METHANE- AND METHANOL-GROWN PSEUDOMONAS METHANICA.
Topics: Alanine; Alcohols; Aspartic Acid; Bicarbonates; Chromatography; Citrates; Ethanol; Fructose; Glucose; Glutamates; Glycine; Heptoses; Hexosephosphates; Malates; Metabolism; Methane; Methanol; Propionates; Pseudomonas; Research; Ribose; Serine | 1965 |
THE IMPORTANCE OF GLYOXYLATE IN AMINO ACID BIOSYNTHESIS IN PLANTS.
Topics: Acetates; Acids; Amino Acids; Carbohydrates; Carbon Dioxide; Fabaceae; Glycine; Glycolates; Glyoxylates; Lipids; Metabolism; Plants; Plants, Edible; Research; Serine | 1965 |
ENTRY OF GLUCOSE CARBON INTO AMINO ACIDS OF RAT BRAIN AND LIVER IN VIVO AFTER INJECTION OF UNIFORMLY 14-C-LABELLED GLUCOSE.
Topics: Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Brain; Brain Chemistry; Carbohydrate Metabolism; Carbon; Carbon Isotopes; Chromatography; Glucose; Glutamates; Glutamine; Glycine; Liver; Rats; Research; Serine | 1965 |
[Probable reactions in the photosynthesis of glycine, serine and proline in mixtures of paraformaldehyde and potassium nitrate].
Topics: Formaldehyde; Glycine; Nitrates; Photosynthesis; Polymers; Potassium Compounds; Proline; Serine | 1955 |
Serine metabolism in a mutant-strain of Escherichia coli strain K-12.
Topics: Escherichia coli; Glycine; Serine | 1955 |
The effect of vitamin B12 on some aspects of glycine metabolism.
Topics: Biochemical Phenomena; Choline; Glycine; Serine; Vitamin B 12; Vitamin B 12 Deficiency | 1955 |
Biosynthesis of glycine and serine in normal and folic acid-deficient rats.
Topics: Animals; Fabaceae; Folic Acid; Folic Acid Deficiency; Glycine; Rats; Serine | 1955 |
A new cofactor in the conversion of serine to glycine.
Topics: Biochemical Phenomena; Clostridium; Fabaceae; Glycine; Organic Chemicals; Serine | 1955 |
A study of the mechanism of serine biosynthesis.
Topics: Antimetabolites; Folic Acid; Formaldehyde; Glycine; Liver Extracts; Serine | 1955 |
Studies on the biosynthesis of serine.
Topics: Formaldehyde; Glycine; Liver; Serine | 1955 |
[Interrelations between glycine, serine and threonine in the hen's egg during embryonal development].
Topics: Animals; Chickens; Eggs; Embryo, Mammalian; Embryo, Nonmammalian; Embryonic Development; Fabaceae; Female; Glycine; Serine; Threonine | 1955 |
Gluconeogenesis from glycine and serine in the rat.
Topics: Animals; Carbohydrate Metabolism; Gluconeogenesis; Glucose; Glycine; Rats; Serine | 1960 |
Studies on wheat plants using carbon-14 compounds. XII. Utilization of serine-C14 with special reference to glycine labelling.
Topics: Carbon Radioisotopes; Dietary Fats, Unsaturated; Fabaceae; Glycine; Plant Oils; Serine; Triticum | 1960 |
Stimulatory effects of glycine, L-serine, folic acid and related compounds on growth of cell cultures.
Topics: Cell Culture Techniques; Fabaceae; Folic Acid; Glycine; Physiological Phenomena; Serine; Tissue Culture Techniques | 1960 |
Synthesis of serine from glycine in mitochondrial fragments.
Topics: Biochemical Phenomena; Fabaceae; Glycine; Liver; Mitochondria; Serine | 1960 |
Role of one-carbon precursors in the biosynthesis of deoxyribonucleic acid in bacteriophage infected and growing cells of Escherichia coli.
Topics: Bacteriological Techniques; Bacteriophages; Carbon; Carbon Isotopes; DNA; Escherichia coli; Formates; Glycine; Purines; Pyrimidines; Serine | 1961 |
Identification of a novel point mutation in platelet glycoprotein Ibalpha, Gly to Ser at residue 233, in a Japanese family with platelet-type von Willebrand disease.
Topics: Bleeding Time; Blood Platelets; Blood Proteins; Cell Line; Child, Preschool; Dose-Response Relationship, Drug; Family Health; Genetic Vectors; Genotype; Glycine; Glycoproteins; Hemorrhage; Heterozygote; Humans; Immunoglobulins; Japan; Male; Mutation; Phenotype; Platelet Aggregation; Point Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Ristocetin; Serine; Thrombocytopenia; von Willebrand Diseases; von Willebrand Factor | 2003 |
Cloning and characterization of a GABAA receptor gamma2 subunit variant.
Topics: Alternative Splicing; Amino Acid Motifs; Amino Acid Sequence; Cell Line; Cell Membrane; Cloning, Molecular; Exons; Glycine; Humans; Immunohistochemistry; Introns; Microscopy, Fluorescence; Models, Genetic; Molecular Sequence Data; Mutation; Plasmids; Protein Binding; Proteins; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Threonine; Tissue Distribution; Transfection; Tyrosine | 2004 |
Functional and biochemical analysis of Chlamydia trachomatis MurC, an enzyme displaying UDP-N-acetylmuramate:amino acid ligase activity.
Topics: Alanine; Bacterial Proteins; Chlamydia trachomatis; Culture Media; Escherichia coli; Genetic Complementation Test; Glycine; Kinetics; Mutation; Peptide Synthases; Serine | 2003 |
Mutational analysis of the Acropora millepora PaxD paired domain highlights the importance of the linker region for DNA binding.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cnidaria; DNA; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Genetic Variation; Glycine; Homeodomain Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Paired Box Transcription Factors; PAX3 Transcription Factor; PAX7 Transcription Factor; Protein Binding; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Transcription Factors | 2003 |
Deciphering the molecular basis of the broad substrate specificity of alpha-glucosidase from Bacillus sp. SAM1606.
Topics: alpha-Glucosidases; Amino Acid Sequence; Amino Acids; Asparagine; Bacillus; Binding Sites; Catalysis; Evolution, Molecular; Glycine; Isomaltose; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Oligo-1,6-Glucosidase; Phylogeny; Plasmids; Proline; Serine; Substrate Specificity; Threonine; Trehalose | 2003 |
Distribution and pharmacology of alanine-serine-cysteine transporter 1 (asc-1) in rodent brain.
Topics: Alanine; Amino Acid Transport System A; Amino Acid Transport System ASC; Amino Acid Transport System L; Amino Acid Transport System y+; Animals; beta-Alanine; Blotting, Western; Brain; Brain Chemistry; Cell Line; Cysteine; Dose-Response Relationship, Drug; Embryo, Mammalian; Fusion Regulatory Protein-1; Glycine; Humans; Immunohistochemistry; Kidney; Male; Mice; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Sodium; Synaptosomes; Transfection | 2003 |
Derivatized amino acids relevant to native peptide synthesis by chemical ligation and acyl transfer.
Topics: Acylation; Alanine; Amino Acids; Glycine; Ligation; Models, Chemical; Molecular Structure; Peptides; Serine | 2003 |
Enzymatic and molecular characteristics of the efficiency and specificity of exfoliative toxin cleavage of desmoglein 1.
Topics: Alanine; alpha-Macroglobulins; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Cadherins; Desmoglein 1; DNA, Complementary; Dogs; Enzyme Inhibitors; Glutamic Acid; Glycine; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Point Mutation; Polymerase Chain Reaction; Precipitin Tests; Protein Binding; Protein Sorting Signals; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Serine Proteinase Inhibitors; Staphylococcus aureus; Time Factors; Toxins, Biological | 2004 |
Contribution of astrocytes to hippocampal long-term potentiation through release of D-serine.
Topics: Animals; Astrocytes; Binding Sites; Calcium; Cells, Cultured; Culture Media, Conditioned; Electrophysiology; Glycine; Hippocampus; Long-Term Potentiation; Microscopy, Confocal; Neuroglia; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Synaptosomes; Time Factors | 2003 |
Active release of glycine or D-serine saturates the glycine site of NMDA receptors at the cerebellar mossy fibre to granule cell synapse.
Topics: Animals; Animals, Newborn; Binding, Competitive; Cerebellum; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Kynurenic Acid; Models, Biological; Nerve Fibers; Neurons; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Serine | 2003 |
Phosphorylation and mutation of human cardiac troponin I deferentially destabilize the interaction of the functional regions of troponin I with troponin C.
Topics: Amino Acid Sequence; Arginine; Calcium; Cardiomyopathy, Hypertrophic, Familial; Glycine; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardium; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Serine; Threonine; Troponin C; Troponin I; Tryptophan | 2003 |
Hydrated metal(II) complexes of N-(6-amino-3,4-dihydro-3-methyl-5-nitroso-4-oxopyrimidin-2-yl) derivatives of glycine, glycylglycine, threonine, serine, valine and methionine: a monomeric complex and coordination polymers in one, two and three dimensions
Topics: Amino Acids; Barium; Calcium; Cations, Divalent; Crystallography, X-Ray; Glycine; Glycylglycine; Hydrogen Bonding; Ligands; Methionine; Molecular Conformation; Molecular Structure; Molecular Weight; Nitroso Compounds; Polymers; Pyrimidinones; Serine; Strontium; Threonine; Valine; Water | 2004 |
Tazobactam inactivation of SHV-1 and the inhibitor-resistant Ser130 -->Gly SHV-1 beta-lactamase: insights into the mechanism of inhibition.
Topics: beta-Lactamases; Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; Glycine; Kinetics; Mass Spectrometry; Models, Chemical; Penicillanic Acid; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tazobactam; Trypsin | 2004 |
Characterization and metabolic function of a peroxisomal sarcosine and pipecolate oxidase from Arabidopsis.
Topics: Amino Acid Sequence; Arabidopsis; Cucurbita; Cysteine; DNA, Complementary; Escherichia coli; Formaldehyde; Gas Chromatography-Mass Spectrometry; Glycine; Hydrogen Peroxide; Mass Spectrometry; Microbodies; Models, Chemical; Molecular Sequence Data; Nitrogen; Oxidoreductases Acting on CH-NH Group Donors; Oxygen; Peroxisomes; Protein Structure, Tertiary; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Sarcosine; Sequence Homology, Amino Acid; Serine; Spectrometry, Mass, Electrospray Ionization; Tetrahydrofolates | 2004 |
Studies on the crystalline lens. III. Incorporation of glycine and serine in the proteins of lenses cultured in vitro.
Topics: Amputation Stumps; Glycine; In Vitro Techniques; Lens, Crystalline; Lenses; Serine | 1950 |
Antagonisms in the utilization of D-amino acids by lactic acid bacteria. II. Influence of DL-serine and glycine on the utilization of D-alanine.
Topics: Alanine; Amino Acids; Dietary Proteins; Fabaceae; Glycine; Lactic Acid; Lactobacillus; Serine | 1950 |
[Serine and glycocoll metabolism].
Topics: Glycine; Serine | 1950 |
Utilization of glyoxylic and glycolic acids by a Neurospora mutant requiring glycine or serine.
Topics: Glycine; Glycolates; Neurospora; Serine | 1951 |
Growth on diets devoid of glycine, serine, and cystine, and low in choline.
Topics: Amino Acids; Choline; Cystine; Diet; Glycine; Growth; Humans; Serine | 1952 |
INTERCONVERSION among nonessential amino acids.
Topics: Amino Acids; Cystine; Dietary Proteins; Glycine; Humans; Serine | 1952 |
Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands.
Topics: Alanine; Amino Acid Sequence; Animals; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cycloserine; Databases as Topic; Escherichia coli; Excitatory Amino Acid Antagonists; Glycine; Humans; Hydrogen Bonding; Indoles; Kynurenic Acid; Ligands; Mice; Models, Chemical; Models, Molecular; Molecular Sequence Data; Potassium Channels; Proline; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sequence Homology, Amino Acid; Serine; Threonine; Tryptophan; Water | 2004 |
Evidence that the C-terminus of the D1 polypeptide of photosystem II is ligated to the manganese ion that undergoes oxidation during the S1 to S2 transition: an isotope-edited FTIR study.
Topics: Alanine; Carbon; Carbon Isotopes; Carboxylic Acids; Cations, Divalent; Cyanobacteria; Glycine; Isotope Labeling; Ligands; Manganese; Mutagenesis, Site-Directed; Oxidation-Reduction; Peptide Fragments; Photolysis; Photosystem II Protein Complex; Serine; Spectroscopy, Fourier Transform Infrared | 2004 |
Multiconformational states in phosphoglycerate dehydrogenase.
Topics: Allosteric Site; Carbohydrate Dehydrogenases; Computer Simulation; Crystallography, X-Ray; Enzyme Inhibitors; Escherichia coli Proteins; Glycine; Light; Models, Molecular; Phosphoglycerate Dehydrogenase; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Quaternary; Protein Structure, Tertiary; Protein Subunits; Scattering, Radiation; Serine; Substrate Specificity; Tryptophan | 2004 |
Horseradish peroxidase mutants that autocatalytically modify their prosthetic heme group: insights into mammalian peroxidase heme-protein covalent bonds.
Topics: Animals; Carboxylic Acids; Catalysis; Cell Line; Chromatography, High Pressure Liquid; Cloning, Molecular; DNA; Electrophoresis, Polyacrylamide Gel; Genetic Variation; Glutamic Acid; Glycine; Heme; Horseradish Peroxidase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Insecta; Kinetics; Leucine; Mass Spectrometry; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Peroxidase; Phenylalanine; Porphyrins; Protein Structure, Secondary; Serine; Spectrophotometry; Time Factors; Ultraviolet Rays | 2004 |
Ala226 to Gly and Ser189 to Asp mutations convert rat chymotrypsin B to a trypsin-like protease.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Benzamidines; Chymotrypsin; Chymotrypsinogen; Glycine; Kinetics; Molecular Sequence Data; Mutation; Peptide Hydrolases; Protein Conformation; Rats; Serine; Substrate Specificity; Trypsin; Trypsin Inhibitors | 2004 |
Construction of a dual chain pseudotetrameric chicken avidin by combining two circularly permuted avidins.
Topics: Amino Acid Sequence; Animals; Avidin; Binding Sites; Biotin; Chickens; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Endopeptidase K; Glycine; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Protein Binding; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Sensitivity and Specificity; Serine | 2004 |
Identification of two novel clusters of ultrahigh-sulfur keratin-associated protein genes on human chromosome 11.
Topics: Amino Acid Sequence; Base Sequence; Chromosomes, Human, Pair 11; Cysteine; Gene Expression; Genome, Human; Glycine; Hair Follicle; Humans; Keratins; Molecular Sequence Data; Multigene Family; Open Reading Frames; Promoter Regions, Genetic; Sequence Alignment; Serine; Skin; Tissue Distribution | 2004 |
The Gly482Ser variant in the peroxisome proliferator-activated receptor gamma coactivator-1 is not associated with diabetes-related traits in non-diabetic German and Dutch populations.
Topics: Adult; Amino Acid Substitution; Diabetes Mellitus; Female; Genotype; Germany; Glucose Clamp Technique; Glucose Tolerance Test; Glycine; Humans; Insulin; Male; Muscle, Skeletal; Mutation, Missense; Netherlands; Oxygen Consumption; Reference Values; Serine; Transcription Factors | 2004 |
A young renal transplant recipient with unexplained resting sinus tachycardia, hypertension and beta-blocker resistance.
Topics: Adult; Arginine; Glycine; Homozygote; Humans; Hypertension; Kidney Diseases; Kidney Transplantation; Male; Polymorphism, Genetic; Receptors, Adrenergic, beta-1; Renal Dialysis; Serine; Tachycardia, Sinus | 2004 |
Gene knockout of glycine transporter 1: characterization of the behavioral phenotype.
Topics: Amino Acid Transport Systems, Neutral; Amphetamines; Animals; Behavior, Animal; Central Nervous System Stimulants; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gene Targeting; Glycine; Glycine Plasma Membrane Transport Proteins; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Patch-Clamp Techniques; Phenotype; Prosencephalon; Receptors, N-Methyl-D-Aspartate; Serine; Sodium; Synapses | 2004 |
Serine hydroxymethyltransferase: role of glu75 and evidence that serine is cleaved by a retroaldol mechanism.
Topics: Aldehydes; Animals; Crystallography, X-Ray; Formyltetrahydrofolates; Glutamic Acid; Glycine; Glycine Hydroxymethyltransferase; Models, Molecular; Protein Conformation; Rabbits; Serine; Structure-Activity Relationship; Tetrahydrofolates | 2004 |
Adult-onset ataxia telangiectasia due to ATM 5762ins137 mutation homozygosity.
Topics: Adult; Alanine; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Blood Cells; Blotting, Western; Cell Cycle Proteins; Cell Line; Cerebellum; DNA Mutational Analysis; DNA-Binding Proteins; Glycine; Homozygote; Humans; Magnetic Resonance Imaging; Male; Phosphorylation; Point Mutation; Protein Serine-Threonine Kinases; Radiation Tolerance; RNA Splice Sites; Serine; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2004 |
The G115S mutation associated with maturity-onset diabetes of the young impairs hepatocyte nuclear factor 4alpha activities and introduces a PKA phosphorylation site in its DNA-binding domain.
Topics: Age of Onset; Amino Acid Substitution; Binding Sites; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus; DNA-Binding Proteins; DNA, Neoplasm; Glycine; HeLa Cells; Hepatocyte Nuclear Factor 4; Histidine; Humans; Liver Neoplasms; Mutation, Missense; Phosphoproteins; Phosphorylation; Serine; Substrate Specificity; Transcription Factors | 2004 |
External pH changes affect NMDA-evoked and spontaneous release of cholecystokinin, somatostatin and noradrenaline from rat cerebrocortical nerve endings.
Topics: Animals; Botulinum Toxins; Calcium; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Cholecystokinin; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; Hydrogen-Ion Concentration; In Vitro Techniques; Male; N-Methylaspartate; Nerve Endings; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Norepinephrine; Potassium; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Serine; Somatostatin; Synaptosomes | 2004 |
RET exon 11 (G691S) polymorphism is significantly more frequent in sporadic medullary thyroid carcinoma than in the general population.
Topics: Carcinoma, Medullary; Exons; Female; Genetic Variation; Glycine; Humans; Male; Mutation; Polymorphism, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Serine; Thyroid Neoplasms; Transcription, Genetic | 2004 |
The relative affective potency of glycine, L-serine and sucrose as assessed by a brief-access taste test in inbred strains of mice.
Topics: Animals; Dose-Response Relationship, Drug; Food Preferences; Glycine; Male; Mice; Mice, Inbred Strains; Receptors, G-Protein-Coupled; Serine; Species Specificity; Sucrose; Sweetening Agents; Taste; Taste Buds | 2004 |
Transformation of the mechanism of triple-helix peptide folding in the absence of a C-terminal nucleation domain and its implications for mutations in collagen disorders.
Topics: Amino Acid Sequence; Circular Dichroism; Collagen; Collagen Diseases; Glycine; Humans; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutation; Peptides; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Temperature; Time Factors | 2004 |
Novel CLCN1 mutations in Taiwanese patients with myotonia congenita.
Topics: Adolescent; Adult; Aspartic Acid; Child; Chloride Channels; DNA Mutational Analysis; Female; Glycine; Humans; Isoleucine; Male; Mutation, Missense; Myotonia Congenita; Phenylalanine; Polymorphism, Genetic; Proline; Serine; Taiwan; Threonine | 2004 |
A polymorphism of the beta1-adrenergic receptor is associated with low extraversion.
Topics: Adolescent; Adult; Arginine; Chi-Square Distribution; Cluster Analysis; Ethnicity; Extraversion, Psychological; Female; Gene Frequency; Glycine; Humans; Male; Personality Inventory; Phenotype; Polymorphism, Genetic; Psychiatric Status Rating Scales; Receptors, Adrenergic, beta-1; Regression Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Sex Characteristics; Surveys and Questionnaires | 2004 |
Role of amino-acid residue 95 in substrate specificity of phosphagen kinases.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Arginine Kinase; Binding Sites; Creatine Kinase; Glycine; Kinetics; Models, Molecular; Molecular Sequence Data; Oligochaeta; Phosphotransferases (Nitrogenous Group Acceptor); Recombinant Proteins; Serine; Structure-Activity Relationship; Substrate Specificity; Thermodynamics | 2004 |
The spinal antinociceptive effect of nocistatin in neuropathic rats is blocked by D-serine.
Topics: Analgesics, Opioid; Anesthesia, Spinal; Animals; Dose-Response Relationship, Drug; Glycine; Hyperalgesia; Injections, Spinal; Ligation; Opioid Peptides; Pain; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sciatic Neuropathy; Serine; Stereoisomerism | 2004 |
Response to lysine intake in composition of body weight gain and efficiency of lysine utilization of growing male chickens from two genotypes.
Topics: Amino Acids; Animals; Body Composition; Chickens; Cysteine; Energy Metabolism; Genotype; Glycine; Isoleucine; Lipid Metabolism; Lysine; Male; Methionine; Proline; Proteins; Serine; Weight Gain | 2004 |
Dietary glycine needs of broiler chicks.
Topics: Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Glycine; Male; Nutritional Requirements; Regression Analysis; Serine; Threonine; Weight Gain | 2004 |
The crystal structure of an oxidatively stable subtilisin-like alkaline serine protease, KP-43, with a C-terminal beta-barrel domain.
Topics: Animals; Bacillus; Binding Sites; Catalysis; Cattle; Crystallography, X-Ray; Electrons; Electrophoresis, Polyacrylamide Gel; Endopeptidase K; Genes, Dominant; Glycine; Methionine; Models, Molecular; Oxygen; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Serine Endopeptidases; Substrate Specificity; Subtilisins; Time Factors | 2004 |
Metabolic properties of Eubacterium pyruvativorans, a ruminal 'hyper-ammonia-producing' anaerobe with metabolic properties analogous to those of Clostridium kluyveri.
Topics: Adenosine Triphosphate; Alanine; Animals; Aspartic Acid; Caseins; Clostridium; Crotonates; Energy Metabolism; Eubacterium; Fatty Acids, Volatile; Fermentation; Glycine; Lactic Acid; Leucine; Peptides; Proline; Pyruvic Acid; Rumen; Serine; Threonine | 2004 |
Inhibitor-resistant class A beta-lactamases: consequences of the Ser130-to-Gly mutation seen in Apo and tazobactam structures of the SHV-1 variant.
Topics: Alanine; Amino Acid Substitution; Apoenzymes; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Catalysis; Crystallography, X-Ray; Enzyme Inhibitors; Escherichia coli Proteins; Genetic Variation; Glutamic Acid; Glycine; Hydrolysis; Models, Molecular; Mutagenesis, Site-Directed; Penicillanic Acid; Serine; Tazobactam | 2004 |
The ser9gly SNP in the dopamine D3 receptor causes a shift from cAMP related to PGE2 related signal transduction mechanisms in transfected CHO cells.
Topics: Amino Acid Substitution; Animals; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dinoprostone; Dopamine; Glycine; Humans; Polymorphism, Single Nucleotide; Receptors, Dopamine D2; Receptors, Dopamine D3; Serine; Signal Transduction; Transfection | 2004 |
Putative NMDA receptors in Hydra: a biochemical and functional study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Binding Sites; Cell Membrane; Concanavalin A; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Glutamic Acid; Glutathione; Glycine; Hydra; Kynurenic Acid; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Serine; Strychnine | 2004 |
Mutations in the pore region modify epithelial sodium channel gating by shear stress.
Topics: Amiloride; Amino Acid Sequence; Animals; Binding Sites; Cysteine; Electrophysiology; Epithelial Sodium Channels; Glycine; Kinetics; Leucine; Mice; Models, Chemical; Molecular Sequence Data; Mutation; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; RNA, Complementary; Serine; Sodium; Sodium Channels; Stress, Mechanical; Time Factors; Tryptophan; Xenopus laevis | 2005 |
A Gly482Ser polymorphism of the peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) gene is associated with type 2 diabetes in Caucasians.
Topics: Case-Control Studies; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genetic Predisposition to Disease; Glycine; Humans; Male; Polymorphism, Genetic; Risk Factors; Serine; Slovenia; Transcription Factors; White People | 2004 |
Low serine hydroxymethyltransferase activity in the human placenta has important implications for fetal glycine supply.
Topics: Animals; Birth Weight; Carbon Radioisotopes; Female; Fetal Development; Glycine; Glycine Hydroxymethyltransferase; Humans; Placenta; Pregnancy; Rats; Rats, Wistar; Serine; Sheep; Species Specificity | 2005 |
Dissemination of lipid A deacylases (pagL) among gram-negative bacteria: identification of active-site histidine and serine residues.
Topics: Amino Acid Sequence; Antibodies; Bacterial Proteins; Binding Sites; Bordetella bronchiseptica; Carbohydrate Sequence; Carboxylic Ester Hydrolases; Centrifugation; Cloning, Molecular; Disaccharides; DNA; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gas Chromatography-Mass Spectrometry; Glycine; Histidine; Immunoblotting; Lipid A; Lipids; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Plasmids; Pseudomonas aeruginosa; Salmonella enterica; Sequence Homology, Amino Acid; Serine; Spectrometry, Mass, Electrospray Ionization | 2005 |
Accumulation of aluminum by primary cultured astrocytes from aluminum amino acid complex and its apoptotic effect.
Topics: Aluminum Compounds; Amino Acids; Animals; Animals, Newborn; Apoptosis; Astrocytes; Cells, Cultured; Glutamates; Glutamine; Glycine; Methionine Sulfoximine; Mice; Mice, Inbred ICR; Serine | 2005 |
Studies of the Gly482Ser polymorphism of the peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) gene in Danish subjects with the metabolic syndrome.
Topics: Adult; Aged; Alleles; Denmark; Female; Gene Frequency; Genotype; Glycine; Heat-Shock Proteins; Humans; Male; Metabolic Syndrome; Middle Aged; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Serine; Transcription Factors | 2005 |
Role of protein phosphatase 2A in mGluR5-regulated MEK/ERK phosphorylation in neurons.
Topics: Animals; Blotting, Western; Brain; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glycine; Immunoprecipitation; MAP Kinase Kinase 1; Marine Toxins; Microscopy, Confocal; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Okadaic Acid; Oxazoles; Peptides; Phenylacetates; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Serine; Signal Transduction; Threonine; Time Factors; Up-Regulation | 2005 |
Palmitoylated cysteine 192 is required for RhoB tumor-suppressive and apoptotic activities.
Topics: Alanine; Amino Acid Sequence; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cysteine; DNA Primers; Genes, Tumor Suppressor; Glycine; Humans; In Situ Nick-End Labeling; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Palmitic Acid; Promoter Regions, Genetic; Protein Biosynthesis; Protein Prenylation; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; Sequence Homology, Amino Acid; Serine; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1; Transcription, Genetic; Transfection; Transforming Growth Factor beta | 2005 |
Clinical and positron emission tomography of Parkinson's disease caused by LRRK2.
Topics: Aged; Amino Acid Sequence; Animals; Dihydroxyphenylalanine; DNA Mutational Analysis; Family Health; Female; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mutation; Parkinson Disease; Pedigree; Positron-Emission Tomography; Protein Serine-Threonine Kinases; Serine | 2005 |
PGC-1alpha Gly482Ser polymorphism associates with hypertension among Danish whites.
Topics: Adult; Aged; Blood Pressure; Denmark; Female; Genetic Predisposition to Disease; Genotype; Glycine; Heat-Shock Proteins; Humans; Hypertension; Male; Middle Aged; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Reverse Transcriptase Polymerase Chain Reaction; Risk; Serine; Sex Characteristics; Transcription Factors; White People | 2005 |
Glycine binding site of the synaptic NMDA receptor in subpostremal NTS neurons.
Topics: Aminoquinolines; Animals; Animals, Newborn; Binding Sites; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Glycine Agents; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine; Solitary Nucleus; Strychnine; Synapses | 2005 |
Gene mutation detected in Parkinson's disease.
Topics: Amino Acid Substitution; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine | 2005 |
Dietary vitamin B-6 restriction does not alter rates of homocysteine remethylation or synthesis in healthy young women and men.
Topics: Adult; Carbon Isotopes; Deuterium; Female; Glycine; Homocysteine; Humans; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pyridoxal Phosphate; Serine; Vitamin B 6 | 2005 |
Identification and functional characterization of a novel low affinity aromatic-preferring amino acid transporter (arpAT). One of the few proteins silenced during primate evolution.
Topics: Alanine; Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Amino Acids; Amino Acids, Aromatic; Animals; Arginine; Biological Transport; Blotting, Northern; Blotting, Western; Cell Lineage; Chickens; Cloning, Molecular; Cysteine; Dimerization; DNA, Complementary; Dogs; Dose-Response Relationship, Drug; Evolution, Molecular; Gene Library; Gene Silencing; Glutamine; Glycine; HeLa Cells; Humans; In Situ Hybridization; Inhibitory Concentration 50; Intestine, Small; Kidney; Kinetics; Levodopa; Mice; Molecular Sequence Data; Open Reading Frames; Pan troglodytes; Phylogeny; Proline; Protein Binding; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Sodium; Transfection | 2005 |
Hb riccarton [alpha51(CE9)Gly-->Ser]: a variant arising from a novel mutation in the alpha1 gene.
Topics: Amino Acid Substitution; Child, Preschool; Glycine; Hemoglobins, Abnormal; Humans; Male; Point Mutation; Serine | 2005 |
N-terminal control of small heat shock protein oligomerization: changes in aggregate size and chaperone-like function.
Topics: alpha-Crystallin A Chain; Animals; Archaeal Proteins; Cattle; Dimerization; Glycine; Heat-Shock Proteins; Methanococcus; Microscopy, Electron; Microscopy, Electron, Transmission; Molecular Chaperones; Polymerase Chain Reaction; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Serine; Sodium Dodecyl Sulfate; Time Factors | 2005 |
The structure of Apo R268A human aldose reductase: hinges and latches that control the kinetic mechanism.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); Alanine; Aldehyde Reductase; Arginine; Base Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; Glycine; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; NADP; Protein Conformation; Serine; Static Electricity; Stereoisomerism; Temperature; Ultraviolet Rays | 2005 |
SOD1 mutations in amyotrophic lateral sclerosis. Results from a multicenter Italian study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Blotting, Northern; Cohort Studies; DNA Mutational Analysis; Exons; Family Health; Female; Genotype; Glycine; Humans; Introns; Italy; Male; Middle Aged; Mutation; Pedigree; Polymorphism, Genetic; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Statistics, Nonparametric; Superoxide Dismutase; Superoxide Dismutase-1 | 2005 |
Polymorphisms of the receptor of advanced glycation endproducts (RAGE) and the development of nephropathy in type 1 diabetic patients.
Topics: Amino Acid Substitution; Arginine; Cross-Sectional Studies; Cysteine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Exons; Female; Genotype; Glycine; Humans; Male; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serine | 2005 |
Backbone and side-chain 1H, 15N, and 13C assignments for the beta domain of the bacterial cell division protein DivIB.
Topics: Amino Acid Sequence; Amino Acids, Aromatic; Bacterial Proteins; Carbon Isotopes; Cell Division; Cell Fractionation; Chromatography, Ion Exchange; Escherichia coli; Geobacillus stearothermophilus; Glutathione Transferase; Glycine; Hydrogen-Ion Concentration; Molecular Sequence Data; Molecular Weight; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protons; Recombinant Fusion Proteins; Serine; Stereoisomerism | 2005 |
Inhibition of growth of Mycobacterium smegmatis and of cell wall synthesis by D-serine.
Topics: Amino Acids; Amino Sugars; Aspartic Acid; Cell Wall; Diaminopimelic Acid; Glycine; Mycobacterium smegmatis; Serine | 1974 |
Natural mutations in a 2'-5' oligoadenylate synthetase transgene revealed residues essential for enzyme activity.
Topics: 2',5'-Oligoadenylate Synthetase; Amino Acid Sequence; Animals; Enzyme Activation; Glycine; Humans; Isoenzymes; Lysine; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Serine; Transgenes | 2005 |
Genetic testing in Parkinson's disease.
Topics: Female; Genetic Testing; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine | 2005 |
Base catalysis of chromophore formation in Arg96 and Glu222 variants of green fluorescent protein.
Topics: Amino Acid Sequence; Anions; Arginine; Carbon; Catalysis; Glutamic Acid; Glycine; Green Fluorescent Proteins; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrogen; Peptides; Protein Binding; Protons; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry; Temperature; Time Factors; Trypsin; Tyrosine; Ultraviolet Rays | 2005 |
5-Formyltetrahydrofolate is an inhibitory but well tolerated metabolite in Arabidopsis leaves.
Topics: Arabidopsis; Carbon Dioxide; Carbon-Nitrogen Ligases; Catalysis; DNA, Bacterial; Flowers; Formate-Tetrahydrofolate Ligase; Formyltetrahydrofolates; Glycine; Glycine Hydroxymethyltransferase; Hydrolysis; Leucovorin; Mitochondria; Models, Biological; Models, Chemical; Models, Genetic; Mutagenesis, Site-Directed; Mutation; Phenotype; Photosynthesis; Plant Leaves; Protein Isoforms; RNA; Serine; Temperature; Tetrahydrofolates; Time Factors | 2005 |
Mutational and structural analyses of the hinge region of membrane type 1-matrix metalloproteinase and enzyme processing.
Topics: Amino Acid Sequence; Animals; Arginine; Binding Sites; Biotinylation; Catalysis; Catalytic Domain; Cell Membrane; Computer Simulation; DNA Mutational Analysis; Electrophoresis, Polyacrylamide Gel; Gene Deletion; Glycine; Haplorhini; Humans; Immunoblotting; Immunoprecipitation; Matrix Metalloproteinase 16; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plasmids; Point Mutation; Proline; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Time Factors; Transfection; Vaccinia virus | 2005 |
On the interaction between amiloride and its putative alpha-subunit epithelial Na+ channel binding site.
Topics: Amiloride; Animals; Binding Sites; Diuretics; Dose-Response Relationship, Drug; Epithelial Sodium Channels; Glycine; Histidine; Hydrogen-Ion Concentration; Ions; Kinetics; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oocytes; Patch-Clamp Techniques; Protein Binding; Protein Conformation; Protein Structure, Quaternary; Protein Structure, Tertiary; RNA, Complementary; Serine; Sodium; Sodium Channels; Xenopus laevis | 2005 |
Role of the glycine site of the N-methyl-D-aspartate receptor in synaptic plasticity induced by pairing.
Topics: Afferent Pathways; Animals; Electric Stimulation; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Kynurenic Acid; Long-Term Potentiation; Neuronal Plasticity; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Synapses | 2005 |
The internal cavity of the staphylococcal alpha-hemolysin pore accommodates approximately 175 exogenous amino acid residues.
Topics: Amino Acids; Bacterial Toxins; Base Sequence; DNA, Bacterial; Glycine; Hemolysin Proteins; Models, Molecular; Molecular Sequence Data; Mutation; Protein Denaturation; Protein Structure, Tertiary; Protein Subunits; Serine; Staphylococcus; Temperature | 2005 |
Structural consequences of the inhibitor-resistant Ser130Gly substitution in TEM beta-lactamase.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Enzyme Inhibitors; Glycine; Kinetics; Models, Molecular; Serine | 2005 |
Clavulanic acid inactivation of SHV-1 and the inhibitor-resistant S130G SHV-1 beta-lactamase. Insights into the mechanism of inhibition.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Chromatography, Liquid; Clavulanic Acid; Drug Resistance, Microbial; Escherichia coli; Glycine; Kinetics; Mass Spectrometry; Microbial Sensitivity Tests; Models, Chemical; Peptides; Serine; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Trypsin; Ultraviolet Rays | 2005 |
Habit learning and the genetics of the dopamine D3 receptor: evidence from patients with schizophrenia and healthy controls.
Topics: Adult; Analysis of Variance; Cues; DNA Mutational Analysis; Female; Glycine; Habits; Humans; Learning; Male; Middle Aged; Neuropsychological Tests; Polymorphism, Genetic; Predictive Value of Tests; Psychiatric Status Rating Scales; Receptors, Dopamine D2; Receptors, Dopamine D3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Schizophrenia; Schizophrenic Psychology; Serine; Task Performance and Analysis | 2005 |
Escaping Parkinson's disease: a neurologically healthy octogenarian with the LRRK2 G2019S mutation.
Topics: Adult; Aged; Aged, 80 and over; DNA Mutational Analysis; Family Health; Female; Follow-Up Studies; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine | 2005 |
Phosphorylation of the homeotic tumor suppressor Cdx2 mediates its ubiquitin-dependent proteasome degradation.
Topics: Adenocarcinoma; Alanine; Alkaline Phosphatase; Amino Acid Sequence; Amino Acid Substitution; Animals; Caco-2 Cells; CDX2 Transcription Factor; Chlorocebus aethiops; Colonic Neoplasms; Consensus Sequence; Conserved Sequence; COS Cells; Cyclin-Dependent Kinase 2; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glycine; Homeodomain Proteins; Humans; Intestinal Mucosa; Jejunum; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Sequence Homology, Amino Acid; Serine; Transcription Factors; Transcription, Genetic; Ubiquitin | 2005 |
Age at onset of schizophrenia: interaction between brain-derived neurotrophic factor and dopamine D3 receptor gene variants.
Topics: Adult; Age of Onset; Brain-Derived Neurotrophic Factor; Chi-Square Distribution; Female; Genetic Variation; Glycine; Humans; Male; Methionine; Polymorphism, Genetic; Receptors, Dopamine D2; Receptors, Dopamine D3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Schizophrenia; Serine; Valine | 2005 |
Prenylation-defective human connexin32 mutants are normally localized and function equivalently to wild-type connexin32 in myelinating Schwann cells.
Topics: Amino Acid Motifs; Animals; Codon, Terminator; Connexins; Conserved Sequence; Cysteine; DNA; Evolution, Molecular; Female; Femoral Nerve; Gap Junction beta-1 Protein; Glycine; Humans; Male; Mice; Mice, Transgenic; Mutation; Myelin Sheath; Phenotype; Protein Prenylation; Schwann Cells; Sciatic Nerve; Serine; Tissue Distribution | 2005 |
Characterization of an inducible phenylserine aldolase from Pseudomonas putida 24-1.
Topics: Aldehyde-Lyases; Amino Acid Sequence; Base Sequence; Benzaldehydes; Binding Sites; Enzyme Induction; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Molecular Sequence Data; Pseudomonas putida; Sequence Analysis, DNA; Serine; Substrate Specificity | 2005 |
[Characterization of a canine model of dystrophic bullous epidermolysis (DBE). Development of a gene therapy protocol].
Topics: Animals; Disease Models, Animal; Dogs; Epidermolysis Bullosa Dystrophica; Female; Genetic Therapy; Glycine; Male; Mutation; Serine | 2005 |
Automated assay for the determination of methylmalonic acid, total homocysteine, and related amino acids in human serum or plasma by means of methylchloroformate derivatization and gas chromatography-mass spectrometry.
Topics: Amino Acids; Autoanalysis; Formates; Gas Chromatography-Mass Spectrometry; Glycine; Homocysteine; Humans; Indicators and Reagents; Methionine; Methylmalonic Acid; Plasma; Reference Values; Sensitivity and Specificity; Serine; Serum | 2005 |
Relation of plasma glycine, serine, and homocysteine levels to schizophrenia symptoms and medication type.
Topics: Adult; Amino Acids; Antipsychotic Agents; Clozapine; Female; Glycine; Homocysteine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Serine | 2005 |
G2019S dardarin substitution is a common cause of Parkinson's disease in a Portuguese cohort.
Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; DNA Mutational Analysis; Family Health; Female; Genetic Predisposition to Disease; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Portugal; Protein Serine-Threonine Kinases; Serine | 2005 |
Ser49Gly of beta1-adrenergic receptor is associated with effective beta-blocker dose in dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Aged; Amino Acid Substitution; Cardiomyopathy, Dilated; Codon; Cohort Studies; DNA; Dose-Response Relationship, Drug; Female; Genotype; Glycine; Humans; Male; Middle Aged; Polymorphism, Genetic; Prospective Studies; Receptors, Adrenergic, beta-1; Serine; Survival Rate; Treatment Outcome | 2005 |
Cell-specific expression of N-methyl-D-aspartate receptor subunits in Müller glia and neurons from the chick retina.
Topics: Animals; Blotting, Western; Cells, Cultured; Chick Embryo; Glycine; Isoenzymes; Kynurenic Acid; Neuroglia; Neurons; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Retina; Reverse Transcriptase Polymerase Chain Reaction; Serine; Spermine; Synaptic Membranes | 2005 |
Phosphagen kinase of the giant tubeworm Riftia pachyptila. Cloning and expression of cytoplasmic and mitochondrial isoforms of taurocyamine kinase.
Topics: Amino Acid Sequence; Animals; Annelida; Arginine; Catalysis; Cloning, Molecular; Creatine; Cytoplasm; DNA, Complementary; Evolution, Molecular; Gene Library; Glycine; Helminths; Kinetics; Mitochondria; Molecular Sequence Data; Phosphotransferases (Nitrogenous Group Acceptor); Phylogeny; Protein Isoforms; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Temperature | 2005 |
All four putative selectivity filter glycine residues in KtrB are essential for high affinity and selective K+ uptake by the KtrAB system from Vibrio alginolyticus.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Binding Sites; Biological Transport; Cation Transport Proteins; Cations; Cell Membrane; Escherichia coli; Genetic Variation; Glucosides; Glycine; Ions; Kinetics; Membrane Proteins; Models, Biological; Molecular Sequence Data; Plasmids; Potassium; Potassium Channels; Protein Binding; Protein Structure, Tertiary; Protein Transport; Serine; Sodium; Time Factors; Vibrio alginolyticus | 2005 |
Contribution of conserved glycine residues to ATP action at human P2X1 receptors: mutagenesis indicates that the glycine at position 250 is important for channel function.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Animals; Blotting, Western; Electrophysiology; Extracellular Space; Glycine; Humans; Ion Channels; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Receptors, Purinergic P2; Receptors, Purinergic P2X; Serine; Xenopus | 2005 |
G2019S LRRK2 mutation in French and North African families with Parkinson's disease.
Topics: Adult; Africa, Northern; Aged; Aged, 80 and over; DNA Mutational Analysis; Family Health; Female; France; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mental Status Schedule; Middle Aged; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine | 2005 |
Characteristics of Streptococcus mutans strains lacking the MazEF and RelBE toxin-antitoxin modules.
Topics: Bacterial Toxins; Biofilms; Gene Expression Profiling; Glycine; Hydrogen-Ion Concentration; Serine; Streptococcus mutans; Transcription Factor RelA; Transcription Factor RelB | 2005 |
Parkinson's disease and LRRK2: frequency of a common mutation in U.S. movement disorder clinics.
Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; DNA Mutational Analysis; Family Health; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Movement Disorders; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine; United States | 2006 |
The inhibition of glycogen synthase kinase 3beta by a metabotropic glutamate receptor 5 mediated pathway confers neuroprotection to Abeta peptides.
Topics: Amyloid beta-Peptides; Animals; Benzoates; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; In Vitro Techniques; Indoles; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Morpholines; Neurons; Oncogene Protein v-akt; Peptide Fragments; Phosphorylation; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Serine; Signal Transduction | 2005 |
Thermodynamic functions and intra-particle mass transfer kinetics of structural analogues of a template on molecularly imprinted polymers in liquid chromatography.
Topics: Adsorption; Algorithms; Chromatography, Liquid; Fluorenes; Glycine; Kinetics; Models, Chemical; Particle Size; Phenylalanine; Polymers; Serine; Stereoisomerism; Temperature; Thermodynamics; Tryptophan; Tyrosine | 2005 |
D-amino-acid oxidase is involved in D-serine-induced nephrotoxicity.
Topics: Alkynes; Animals; D-Amino-Acid Oxidase; Glycine; Glycosuria; Kidney; Male; Rats; Rats, Inbred F344; Serine; Species Specificity | 2005 |
Examination of the zinc transporter gene, SLC39A12.
Topics: Alleles; Brain; Cation Transport Proteins; Exons; Genotype; Glycine; Humans; Mutation, Missense; Reference Values; Schizophrenia; Serine; Statistics as Topic | 2006 |
Posttranslational conversion of L-serines to D-alanines is vital for optimal production and activity of the lantibiotic lacticin 3147.
Topics: Alanine; Amino Acid Sequence; Bacteriocins; Chromatography, High Pressure Liquid; Codon; Glycine; Lactococcus lactis; Molecular Sequence Data; Protein Processing, Post-Translational; Serine; Structure-Activity Relationship; Threonine; Valine | 2005 |
Immunocytochemical analysis of D-serine distribution in the mammalian brain reveals novel anatomical compartmentalizations in glia and neurons.
Topics: Aging; Animals; Biomarkers; Brain; Brain Chemistry; Fixatives; Formaldehyde; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamic Acid; Glycine; Immunohistochemistry; Microscopy, Electron; Neuroglia; Neurons; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Glutamate; Serine; Synaptic Vesicles; Tissue Fixation | 2006 |
Metabolic profiling by 13C-NMR spectroscopy: [1,2-13C2]glucose reveals a heterogeneous metabolism in human leukemia T cells.
Topics: Carbon Isotopes; Cell Cycle; Cell Proliferation; Citric Acid Cycle; Glucose; Glutamine; Glycine; Humans; Jurkat Cells; Lactic Acid; Leukemia, T-Cell; Magnetic Resonance Spectroscopy; Models, Biological; Nucleotides; Pentose Phosphate Pathway; Pentoses; Serine | 2006 |
Two brothers with mild congenital erythropoietic porphyria due to a novel genotype.
Topics: Adolescent; Alanine; Child, Preschool; Exons; Genetic Counseling; Genotype; Glycine; Humans; Male; Mutation; Mutation, Missense; Pedigree; Phenotype; Porphyria, Erythropoietic; Porphyrins; Promoter Regions, Genetic; Serine; Siblings; Uroporphyrinogen III Synthetase | 2005 |
A Ser9Gly polymorphism in the dopamine D3 receptor gene (DRD3) and event-related P300 potentials.
Topics: Acoustic Stimulation; Adult; Aged; Brain; Brain Mapping; Event-Related Potentials, P300; Female; Glycine; Humans; Male; Middle Aged; Multivariate Analysis; Polymorphism, Genetic; Receptors, Dopamine D3; Serine; Statistics, Nonparametric | 2006 |
Host-mediated phosphorylation of type III effector AvrPto promotes Pseudomonas virulence and avirulence in tomato.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Gene Expression; Glycine; Host-Parasite Interactions; Immunity, Innate; Models, Biological; Molecular Sequence Data; Nicotiana; Phosphorylation; Phosphotransferases; Plant Diseases; Plant Proteins; Protein Processing, Post-Translational; Pseudomonas syringae; Serine; Solanum lycopersicum; Spectrometry, Mass, Electrospray Ionization; Virulence | 2006 |
Analysis of the LRRK2 G2019S mutation in Alzheimer Disease.
Topics: Aged; Alzheimer Disease; DNA Mutational Analysis; Female; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mutation; Protein Serine-Threonine Kinases; Serine | 2006 |
The Gly482Ser missense mutation of the peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1 alpha) gene associates with reduced insulin sensitivity in normal and glucose-intolerant obese subjects.
Topics: Adult; Amino Acid Substitution; Female; Genetic Predisposition to Disease; Glucose Intolerance; Glycine; Heat-Shock Proteins; Humans; Insulin Resistance; Male; Middle Aged; Mutation, Missense; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Polymorphism, Single Nucleotide; PPAR alpha; PPAR gamma; Serine; Trans-Activators; Transcription Factors | 2005 |
A chondroitin sulfate chain attached to the bone dentin matrix protein 1 NH2-terminal fragment.
Topics: Amino Acid Sequence; Amino Acids; Animals; Blotting, Western; Bone and Bones; Chondroitin Sulfates; Chondroitinases and Chondroitin Lyases; Chromatography; Disaccharides; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix Proteins; Glycine; Glycosaminoglycans; Humans; Molecular Sequence Data; N-Acetylneuraminic Acid; Phosphates; Phosphoproteins; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Serine; Sulfates; Trypsin | 2006 |
Biochemical and pathological characterization of Lrrk2.
Topics: Adult; Aged; Aged, 80 and over; alpha-Synuclein; Amino Acid Sequence; Animals; Blotting, Western; Brain; Cell Line; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Glycine; Humans; Immunohistochemistry; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mice; Middle Aged; Molecular Weight; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine; Time Factors; Transfection | 2006 |
Increased risk of obesity associated with the variant allele of the PPARGC1A Gly482Ser polymorphism in physically inactive elderly men.
Topics: Adult; Age Distribution; Aged; Alleles; Exercise; Female; Glycine; Heat-Shock Proteins; Humans; Leisure Activities; Male; Middle Aged; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Polymorphism, Genetic; Risk Factors; Serine; Sex Characteristics; Transcription Factors | 2006 |
Is endogenous D-serine in the rostral anterior cingulate cortex necessary for pain-related negative affect?
Topics: Animals; Anxiety; D-Amino-Acid Oxidase; Excitatory Amino Acid Antagonists; Fear; Glycine; Gyrus Cinguli; Kynurenic Acid; Male; Membrane Potentials; N-Methylaspartate; Organ Culture Techniques; Pain; Pain Measurement; Pain Threshold; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Stress, Psychological; Synaptic Transmission | 2006 |
Potentiation of the NMDA receptor-mediated responses through the activation of the glycine site by microglia secreting soluble factors.
Topics: Animals; Animals, Newborn; Cell Communication; Cells, Cultured; Culture Media, Conditioned; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Microglia; N-Methylaspartate; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission | 2006 |
Antipsychotic-induced tardive dyskinesia and the Ser9Gly polymorphism in the DRD3 gene: a meta analysis.
Topics: Alleles; Antipsychotic Agents; Chi-Square Distribution; Dyskinesia, Drug-Induced; Female; Glycine; Humans; Male; MEDLINE; Meta-Analysis as Topic; Polymorphism, Genetic; Psychotic Disorders; Receptors, Dopamine D3; Retrospective Studies; Review Literature as Topic; Serine | 2006 |
Functional role of catalytic triad and oxyanion hole-forming residues on enzyme activity of Escherichia coli thioesterase I/protease I/phospholipase L1.
Topics: Alanine; Asparagine; Catalytic Domain; Crystallography; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Glycine; Kinetics; Lysophospholipase; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Oligonucleotides; Periplasmic Proteins; Protein Conformation; Serine | 2006 |
Structural evidence for an enolate intermediate in GFP fluorophore biosynthesis.
Topics: Crystallography, X-Ray; Glycine; Green Fluorescent Proteins; Kinetics; Models, Molecular; Protein Conformation; Protein Processing, Post-Translational; Protein Structure, Secondary; Serine; Tyrosine | 2006 |
Glycine supplementation to low protein, amino acid-supplemented diets supports optimal performance of broiler chicks.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet, Protein-Restricted; Dietary Supplements; Female; Glycine; Male; Serine; Weight Gain | 2006 |
Functional analysis of Ca3.2 T-type calcium channel mutations linked to childhood absence epilepsy.
Topics: Animals; Calcium Channels, T-Type; Cells, Cultured; Child; Epilepsy, Absence; Glycine; Humans; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; Mutation; Mutation, Missense; Rats; Serine | 2006 |
LRRK2 mutations in Spanish patients with Parkinson disease: frequency, clinical features, and incomplete penetrance.
Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Arginine; Child; Child, Preschool; DNA Mutational Analysis; Family Health; Female; Gene Frequency; Genetic Predisposition to Disease; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Pedigree; Protein Serine-Threonine Kinases; Serine; Spain | 2006 |
Time dependent density functional theory modeling of chiroptical properties of small amino acids in solution.
Topics: Alanine; Computer Simulation; Glycine; Models, Chemical; Proline; Quantum Theory; Serine; Solutions; Time Factors | 2006 |
Novel missense mutation of the DNA topoisomerase I gene in SN-38-resistant DLD-1 cells.
Topics: Amino Acid Substitution; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Glycine; Humans; Irinotecan; Mutation, Missense; Protein Conformation; Serine | 2006 |
Prevalence of the LRRK2 G2019S mutation in a UK community based idiopathic Parkinson's disease cohort.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Chromosome Aberrations; Cohort Studies; DNA Mutational Analysis; England; Exons; Female; Gene Frequency; Genes, Dominant; Genetic Carrier Screening; Genetic Testing; Genotype; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Parkinson Disease; Phenotype; Protein Serine-Threonine Kinases; Serine | 2006 |
Mutation of Gly51 to serine in the P-loop of Lactobacillus casei folylpolyglutamate synthetase abolishes activity by altering the conformation of two adjacent loops.
Topics: Amino Acid Sequence; Amino Acid Substitution; Apoenzymes; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Glycine; Lacticaseibacillus casei; Magnesium; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Synthases; Proline; Protein Structure, Secondary; Sequence Alignment; Serine | 2006 |
Mechanism of action and structural requirements of constrained peptide inhibitors of RGS proteins.
Topics: Acetylcholine; Animals; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Glycine; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits; GTPase-Activating Proteins; Humans; Kinetics; Male; Myocytes, Cardiac; Patch-Clamp Techniques; Peptides, Cyclic; Rats; Rats, Inbred WKY; RGS Proteins; Serine; Structure-Activity Relationship; Time Factors | 2006 |
Increased frequency of the LRRK2 G2019S mutation in an elderly Ashkenazi Jewish population is not associated with dementia.
Topics: Aged, 80 and over; Aging; Dementia; DNA Mutational Analysis; Female; Glycine; Humans; Jews; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mutation; Protein Serine-Threonine Kinases; Residence Characteristics; Serine | 2006 |
Interaction of carboranes with biomolecules: formation of dihydrogen bonds.
Topics: Biophysics; Boranes; Carbon; Chemistry, Physical; Glycine; HIV Protease; HIV Protease Inhibitors; Hydrogen; Hydrogen Bonding; Models, Chemical; Molecular Conformation; Phenylalanine; Quantum Theory; Serine; Thermodynamics | 2006 |
A nonsynonymous single-nucleotide polymorphism in the PDZ-Rho guanine nucleotide exchange factor (Ser1416Gly) modulates the risk of lung cancer in Mexican Americans.
Topics: Aged; Alleles; Case-Control Studies; Cell Transformation, Neoplastic; Cyclin D1; DNA, Neoplasm; Female; Genotype; Glycine; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Humans; Lung Neoplasms; Male; Mexican Americans; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Rho Guanine Nucleotide Exchange Factors; Risk Factors; Serine; Signal Transduction; Tumor Suppressor Protein p53 | 2006 |
Elevated T-maze evaluation of anxiety and memory effects of NMDA/glycine-B site ligands injected into the dorsal periaqueductal gray matter and the superior colliculus of rats.
Topics: Animals; Anxiety; Glycine; Kynurenic Acid; Ligands; Male; Maze Learning; Memory; Microinjections; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism; Superior Colliculi | 2006 |
Mechanistic significance of the preparatory migration of hydrogen atoms around the FeMo-co active site of nitrogenase.
Topics: Acetylene; Azotobacter vinelandii; Binding Sites; Glycine; Hydrogen; Hydrogenation; Kinetics; Models, Biological; Models, Molecular; Models, Theoretical; Molybdoferredoxin; Nitrogen; Nitrogenase; Serine; Stereoisomerism | 2006 |
Screening of toxicity biomarkers for methionine excess in rats.
Topics: Amino Acids; Analysis of Variance; Animals; Bilirubin; Biomarkers; Cystathionine; Diet; Gas Chromatography-Mass Spectrometry; Glycine; Hemolysis; Homocysteine; Iron; Male; Methionine; Rats; Rats, Inbred F344; Serine; Spleen | 2006 |
Modulation of D-serine levels via ubiquitin-dependent proteasomal degradation of serine racemase.
Topics: Animals; Autoantigens; Cell Fractionation; Cell Line; Cells, Cultured; Glycine; Humans; Isomerism; Kidney; L-Lactate Dehydrogenase; Membrane Proteins; Mice; Proteasome Endopeptidase Complex; Protein Biosynthesis; Proteins; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Serine; Subcellular Fractions; Transfection; Ubiquitin | 2006 |
Age-related effects of the neuromodulator D-serine on neurotransmission and synaptic potentiation in the CA1 hippocampal area of the rat.
Topics: Aging; Animals; Dose-Response Relationship, Drug; Electrophysiology; Glutamic Acid; Glycine; Hippocampus; Long-Term Potentiation; Male; Nerve Net; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Synaptic Transmission | 2006 |
Spontaneous recovery from hyperglycemia by regeneration of pancreatic beta-cells in Kir6.2G132S transgenic mice.
Topics: Amino Acid Substitution; Animals; Apoptosis; Blood Glucose; Glucose Tolerance Test; Glycine; Hyperglycemia; In Situ Nick-End Labeling; Insulin; Islets of Langerhans; Mice; Mice, Transgenic; Potassium Channels, Inwardly Rectifying; Serine | 2006 |
Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A and the Pro12Ala substitution of PPARG2 predict the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial.
Topics: Amino Acid Substitution; Diabetes Mellitus, Type 2; Disease Progression; Female; Glucose Intolerance; Glycine; Heat-Shock Proteins; Humans; Male; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Polymorphism, Single Nucleotide; PPAR delta; PPAR gamma; Risk Factors; Serine; Transcription Factors | 2006 |
A functional variant of the dopamine D3 receptor is associated with risk and age-at-onset of essential tremor.
Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Amino Acid Sequence; Case-Control Studies; Cells, Cultured; Child; Dopamine; Essential Tremor; Female; France; Genetic Predisposition to Disease; Glycine; Humans; Male; Middle Aged; Molecular Sequence Data; Pedigree; Receptors, Dopamine D3; Serine | 2006 |
Histidine 89 is an essential residue for Hsp70 in the phosphate transfer reaction.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Substitution; Binding Sites; Cytidine Diphosphate; Electrophoresis, Polyacrylamide Gel; Glycine; Histidine; HSP70 Heat-Shock Proteins; Humans; Hydrolysis; Mutagenesis, Site-Directed; Mutant Proteins; Nucleoside-Diphosphate Kinase; Phosphorylation; Protein Structure, Tertiary; Serine | 2006 |
Lipid solvation effects contribute to the affinity of Gly-xxx-Gly motif-mediated helix-helix interactions.
Topics: Alanine; Amino Acid Motifs; Amino Acid Substitution; Bacteriophage M13; Cell Membrane; Dimerization; Glycine; Glycophorins; Lipids; Molecular Sequence Data; Mutation; Protein Conformation; Protein Folding; Protein Structure, Secondary; Serine; Solubility; Viral Core Proteins | 2006 |
The secondary structure analysis of a potent Ser14Gly analog of antiAlzheimer peptide, Humanin, by circular dichroism.
Topics: Alzheimer Disease; Circular Dichroism; Glycine; Humans; Hydrophobic and Hydrophilic Interactions; Intracellular Signaling Peptides and Proteins; Mutation; Protein Structure, Secondary; Serine; Solubility; Temperature; Ultraviolet Rays | 2006 |
Taurine potentiates presynaptic NMDA receptors in hippocampal Schaffer collateral axons.
Topics: Animals; Axons; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Hippocampus; Kynurenic Acid; Male; N-Methylaspartate; Organ Culture Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission; Taurine | 2006 |
Calmodulin isoform-specific activation of a rice calmodulin-binding kinase conferred by only three amino-acids of OsCaM61.
Topics: Alanine; Amino Acid Sequence; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Electrophoretic Mobility Shift Assay; Enzyme Activation; Glycine; Molecular Sequence Data; Mutation; Oryza; Protein Isoforms; Sequence Alignment; Serine; Spectrometry, Fluorescence | 2006 |
Association of a mutation in TRPV3 with defective hair growth in rodents.
Topics: Alopecia; Amino Acid Substitution; Animals; Cell Count; Cloning, Molecular; Cysteine; Dermatitis; Electrophysiology; Glycine; Histamine; Keratinocytes; Mast Cells; Mice; Mice, Nude; Mutation; Rats; Rats, Nude; Serine; Skin; TRPV Cation Channels | 2006 |
The plant-like C2 glycolate cycle and the bacterial-like glycerate pathway cooperate in phosphoglycolate metabolism in cyanobacteria.
Topics: Alcohol Oxidoreductases; Bacterial Proteins; Carbon Dioxide; DNA Mutational Analysis; Gene Expression Regulation, Bacterial; Genes, Bacterial; Glyceric Acids; Glycine; Glycine Decarboxylase Complex; Glycine Hydroxymethyltransferase; Glycolates; Lysine; Mutation; Open Reading Frames; Serine; Synechocystis | 2006 |
Prospective study of FGFR3 mutations as a prognostic factor in nonmuscle invasive urothelial bladder carcinomas.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Cysteine; Female; Glutamic Acid; Glycine; Humans; Leucine; Male; Middle Aged; Multivariate Analysis; Mutation; Phenylalanine; Polymerase Chain Reaction; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Receptor, Fibroblast Growth Factor, Type 3; Sequence Analysis, DNA; Serine; Tyrosine; Urinary Bladder Neoplasms | 2006 |
End-to-end distance distributions and intrachain diffusion constants in unfolded polypeptide chains indicate intramolecular hydrogen bond formation.
Topics: Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Glycine; Guanidine; Hydrogen Bonding; Molecular Structure; Monte Carlo Method; Peptides; Protein Conformation; Protein Denaturation; Serine; Water | 2006 |
Phospholipase C epsilon suppresses integrin activation.
Topics: Amino Acid Substitution; Animals; CHO Cells; Cricetinae; Cricetulus; Down-Regulation; Glycine; Integrins; Phosphoinositide Phospholipase C; ras Proteins; Rats; Serine; Signal Transduction; Threonine; Type C Phospholipases; Valine | 2006 |
Contribution of endogenous glycine site NMDA agonists to excitotoxic retinal damage in vivo.
Topics: Amidohydrolases; Animals; Cell Death; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Retinal Diseases; Retinal Ganglion Cells; Serine | 2006 |
Specific cleavage of DJ-1 under an oxidative condition.
Topics: Blotting, Western; Cell Line, Tumor; Cysteine; Dose-Response Relationship, Drug; Gene Expression; Glycine; Humans; Hydrogen Peroxide; Intracellular Signaling Peptides and Proteins; Mass Spectrometry; Neuroblastoma; Oncogene Proteins; Oxidants; Oxidation-Reduction; Oxidative Stress; Proline; Protein Deglycase DJ-1; Serine | 2006 |
Solution structure of Ser14Gly-humanin, a potent rescue factor against neuronal cell death in Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Apoptosis; Base Sequence; Circular Dichroism; Glycine; Humans; Intracellular Signaling Peptides and Proteins; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Neurons; Neuroprotective Agents; Protein Structure, Secondary; Serine | 2006 |
DsdX is the second D-serine transporter in uropathogenic Escherichia coli clinical isolate CFT073.
Topics: Alanine; Amino Acid Transport Systems; Biological Transport; Culture Media; Cycloserine; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Glycine; Kinetics; Membrane Transport Proteins; Models, Biological; Serine; Threonine | 2006 |
Random mutagenesis of Helicobacter pylori vacA to identify amino acids essential for vacuolating cytotoxic activity.
Topics: Amino Acid Substitution; Bacterial Proteins; Cytotoxins; Dimerization; Glycine; HeLa Cells; Helicobacter pylori; Humans; Hydrophobic and Hydrophilic Interactions; Mutagenesis; Serine; Vacuoles; Valine | 2006 |
The uptake of amino acids by the cyanobacterium Planktothrix rubescens is stimulated by light at low irradiances.
Topics: Acetates; Alanine; Amino Acids; Carbon Isotopes; Cyanobacteria; Dose-Response Relationship, Radiation; Glutamic Acid; Glycine; Leucine; Light; Nitrogen; Serine | 2006 |
Clinical heterogeneity of the LRRK2 G2019S mutation.
Topics: Aged; Aged, 80 and over; Case-Control Studies; DNA Mutational Analysis; Female; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Models, Molecular; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine | 2006 |
Clinical features of Parkinson disease patients with homozygous leucine-rich repeat kinase 2 G2019S mutations.
Topics: Aged; DNA Mutational Analysis; Family Health; Female; Gene Frequency; Genetic Predisposition to Disease; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine | 2006 |
Glycine origin of the methyl substituent on C7'-N of octodiose for the biosynthesis of apramycin.
Topics: Carbohydrate Sequence; Carbon; Carbon Isotopes; Culture Media; Glycine; Molecular Sequence Data; Nebramycin; Nitrogen; Saccharopolyspora; Serine; Threonine | 2006 |
Suppression of methionine-induced hyperhomocysteinemia by glycine and serine in rats.
Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Glycine; Hyperhomocysteinemia; Liver; Methionine; Rats; Serine | 2006 |
G2019S LRRK2 mutation in familial and sporadic Parkinson's disease in Russia.
Topics: Adult; Aged; Aged, 80 and over; DNA Mutational Analysis; Family Health; Female; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Russia; Serine | 2006 |
Parkinsonism, Lrrk2 G2019S, and tau neuropathology.
Topics: Aged; alpha-Synuclein; Brain; Cell Line; Disability Evaluation; Disease Progression; Female; Glycine; Humans; Immunohistochemistry; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Neurofibrillary Tangles; Parkinsonian Disorders; Pedigree; Protein Serine-Threonine Kinases; Serine; tau Proteins | 2006 |
D-serine in the developing human central nervous system.
Topics: Central Nervous System; Child; Child, Preschool; Female; Glycine; Humans; Infant; Infant, Newborn; Male; Neuronal Plasticity; Phosphoglycerate Dehydrogenase; Serine; Stereoisomerism | 2006 |
Mutations in LRRK2 other than G2019S are rare in a north American-based sample of familial Parkinson's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Family Health; Female; Genetic Testing; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; North America; Parkinson Disease; Protein Serine-Threonine Kinases; Serine | 2006 |
LRRK2 G2019S founder haplotype in the Chinese population.
Topics: Asian People; Glycine; Haplotypes; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Parkinson Disease; Protein Serine-Threonine Kinases; Serine | 2007 |
Reciprocal keratin 18 Ser48 O-GlcNAcylation and Ser52 phosphorylation using peptide analysis.
Topics: Acylation; Amino Acid Substitution; Glycine; Keratin-18; Peptides; Phosphorylation; Serine; Structure-Activity Relationship | 2006 |
Glycine conjugates in a lepidopteran insect herbivore--the metabolism of benzylglucosinolate in the cabbage white butterfly, Pieris rapae.
Topics: Animals; Brassicaceae; Butterflies; Cells, Cultured; Feces; Glycine; Indoles; Isotope Labeling; Larva; Molecular Structure; Serine; Thiocyanates; Thioglucosides | 2006 |
Modulation of the W748S mutation in DNA polymerase gamma by the E1143G polymorphismin mitochondrial disorders.
Topics: Amino Acid Sequence; Amino Acid Substitution; Catalytic Domain; DNA; DNA Polymerase gamma; DNA-Directed DNA Polymerase; Enzyme Stability; Glutamic Acid; Glycine; Humans; Mitochondrial Diseases; Models, Molecular; Molecular Sequence Data; Mutation; Nucleotides; Polymorphism, Genetic; Protein Conformation; Serine; Tryptophan | 2006 |
Genetic analysis of LRRK2 mutations in patients with Parkinson disease.
Topics: Adult; Aged; Arginine; Chromosomes, Human, Pair 12; DNA Mutational Analysis; Female; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine | 2006 |
Screening for Lrrk2 G2019S and clinical comparison of Tunisian and North American Caucasian Parkinson's disease families.
Topics: Adult; Aged; Aged, 80 and over; Cross-Cultural Comparison; DNA Mutational Analysis; Family Health; Female; Genetic Testing; Genotype; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; North America; Parkinson Disease; Protein Serine-Threonine Kinases; Serine; Tunisia; White People | 2007 |
In silico experimentation with a model of hepatic mitochondrial folate metabolism.
Topics: Animals; Cytosol; Dose-Response Relationship, Drug; Folic Acid; Glycine; Glycine Hydroxymethyltransferase; Humans; Methionine; Mitochondria, Liver; Models, Biological; Osmolar Concentration; Proteins; Serine; Tetrahydrofolates | 2006 |
Lrrk2 G2019S substitution in frontotemporal lobar degeneration with ubiquitin-immunoreactive neuronal inclusions.
Topics: Aged; Amino Acid Substitution; Dementia; Female; Glycine; Humans; Inclusion Bodies; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Neurons; Protein Serine-Threonine Kinases; Serine; Ubiquitin | 2007 |
No association between the Ser9Gly polymorphism of the dopamine D3 receptor gene and schizophrenia in a Spanish sample.
Topics: Case-Control Studies; Gene Frequency; Genetic Linkage; Genotype; Glycine; Humans; Polymorphism, Single Nucleotide; Receptors, Dopamine D3; Schizophrenia; Serine; Spain | 2007 |
The novel Tau mutation G335S: clinical, neuropathological and molecular characterization.
Topics: Adult; Dementia; DNA Mutational Analysis; Glycine; Humans; Male; Microscopy, Electron, Transmission; Microtubules; Mutation; Neurofibrillary Tangles; Serine; tau Proteins | 2007 |
Is glycine a surrogate for a D-amino acid in the collagen triple helix?
Topics: Alanine; Amino Acids; Circular Dichroism; Collagen; Glycine; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Peptides; Protein Conformation; Protein Folding; Serine; Thermodynamics | 2007 |
Cloning and characterization of scale beta-keratins in the differentiating epidermis of geckoes show they are glycine-proline-serine-rich proteins with a central motif homologous to avian beta-keratins.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Base Sequence; beta-Keratins; Blotting, Northern; Blotting, Southern; Cloning, Molecular; DNA, Complementary; Epidermis; Gene Expression; Glycine; Immunohistochemistry; In Situ Hybridization; Lizards; Molecular Sequence Data; Oligonucleotides; Proline; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology; Serine | 2007 |
Evaluation of LRRK2 G2019S penetrance: relevance for genetic counseling in Parkinson disease.
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; DNA Mutational Analysis; Family Health; Female; Genetic Counseling; Genetic Predisposition to Disease; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Penetrance; Protein Serine-Threonine Kinases; Serine | 2007 |
The G51S purine nucleoside phosphorylase polymorphism is associated with cognitive decline in Alzheimer's disease patients.
Topics: Alleles; Alzheimer Disease; Apolipoprotein E4; Cognition Disorders; Disease Progression; Follow-Up Studies; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Mutation, Missense; Odds Ratio; Polymorphism, Single Nucleotide; Purine-Nucleoside Phosphorylase; Risk Factors; Serine; Time Factors | 2007 |
X-linked NDUFA1 gene mutations associated with mitochondrial encephalomyopathy.
Topics: Animals; Arginine; DNA Mutational Analysis; Electron Transport Complex I; Electrophoresis, Gel, Two-Dimensional; Female; Genes, X-Linked; Glycine; Humans; Male; Mitochondrial Encephalomyopathies; Muscle, Skeletal; NADH Dehydrogenase; Sequence Alignment; Serine | 2007 |
A second report of platelet-type von Willebrand disease with a Gly233Ser mutation in the GPIBA gene.
Topics: Adult; Blood Platelet Disorders; Blood Platelets; Female; Glycine; Humans; Mutation; Platelet Function Tests; Platelet Glycoprotein GPIb-IX Complex; Pregnancy; Pregnancy Complications, Hematologic; Serine; von Willebrand Diseases; von Willebrand Factor | 2007 |
Glycosylation improves the central effects of DAMGO.
Topics: Amides; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Glucose; Glycine; Glycosylation; Hydrophobic and Hydrophilic Interactions; Injections, Intraventricular; Lactose; Male; Mice; Mice, Inbred ICR; Receptors, Opioid, mu; Serine; Solubility; Water; Xylose | 2007 |
Mineral proximity influences mechanical response of proteins in biological mineral-protein hybrid systems.
Topics: Biocompatible Materials; Biopolymers; Calcium Carbonate; Chemistry, Organic; Extracellular Matrix Proteins; Glycine; Hydrogen Bonding; Macromolecular Substances; Minerals; Molecular Conformation; Protein Structure, Tertiary; Proteins; Serine; Surface Properties; Water | 2007 |
High-affinity glycine and glutamate transport in pig forebrain white and gray matter: a quantitative study.
Topics: Animals; Biological Transport; Excitatory Amino Acid Transporter 2; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Glutathione; Glycine; Glycine Hydroxymethyltransferase; Glycine Plasma Membrane Transport Proteins; Kainic Acid; Prosencephalon; Sarcosine; Serine; Swine | 2007 |
A novel fibrinogen variant--Praha I: hypofibrinogenemia associated with gamma Gly351Ser substitution.
Topics: Adult; Amino Acid Sequence; Blood; Female; Fibrinogen; Glycine; Humans; Male; Microscopy, Electron, Scanning; Middle Aged; Molecular Sequence Data; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2007 |
Double mutant P96S/S120G of Nm23-H1 abrogates its NDPK activity and motility-suppressive ability.
Topics: Amino Acid Substitution; Cell Movement; Glycine; Humans; Mutation; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Proline; Recombinant Proteins; Serine; Tumor Cells, Cultured | 2007 |
Site specific phosphorylation of cytochrome c oxidase subunits I, IVi1 and Vb in rabbit hearts subjected to ischemia/reperfusion.
Topics: Amino Acid Sequence; Animals; Chromatography, Liquid; Electron Transport Complex IV; Electrophoresis, Polyacrylamide Gel; Glycine; Heart; Molecular Sequence Data; Myocardial Reperfusion Injury; Myocardium; Phosphorylation; Protein Conformation; Protein Structure, Tertiary; Protein Subunits; Rabbits; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine | 2007 |
[Association of Gly82Ser polymorphism of receptor for advanced glycation end products gene in a type 2 diabetic Chinese population].
Topics: Aged; Amino Acid Substitution; Asian People; China; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genotype; Glycine; Humans; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serine | 2007 |
Systematic Analysis of proteoglycan modification sites in Caenorhabditis elegans by scanning mutagenesis.
Topics: Amino Acid Sequence; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cells, Cultured; Drosophila melanogaster; Glycine; Glycosylation; Golgi Apparatus; Molecular Sequence Data; Mucins; Mutagenesis, Site-Directed; Pentosyltransferases; Proline; Proteoglycans; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Substrate Specificity; Syndecans; UDP Xylose-Protein Xylosyltransferase | 2007 |
Molecular basis for substrate discrimination by glycine transporters.
Topics: Animals; Electrophysiology; Female; Glycine; Glycine Plasma Membrane Transport Proteins; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oocytes; Peptide Fragments; Sequence Homology, Amino Acid; Serine; Substrate Specificity; Xenopus laevis | 2007 |
MAPK-pathway activity, Lrrk2 G2019S, and Parkinson's disease.
Topics: Aged; Aged, 80 and over; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Leukocytes; Male; Mitogen-Activated Protein Kinases; Mutation; Norway; Parkinson Disease; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Signal Transduction; Statistics, Nonparametric | 2007 |
Receptor for advanced glycation end products Glycine 82 Serine polymorphism and risk of cardiovascular events in rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Cardiovascular Diseases; Genetic Predisposition to Disease; Glycine; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Linkage Disequilibrium; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Factors; Serine | 2007 |
Spatial orientation of mitochondrial processing peptidase and a preprotein revealed by fluorescence resonance energy transfer.
Topics: Amino Acid Sequence; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Glycine; Green Fluorescent Proteins; Lysine; Metalloendopeptidases; Mitochondria; Mitochondrial Processing Peptidase; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Peptide Hydrolases; Saccharomyces cerevisiae; Serine | 2007 |
Prevalence and clinical features of common LRRK2 mutations in Australians with Parkinson's disease.
Topics: Aged; Australia; Cohort Studies; DNA Mutational Analysis; Family Health; Female; Genetic Predisposition to Disease; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Prevalence; Protein Serine-Threonine Kinases; Serine | 2007 |
Phosphoserine aminotransferase deficiency: a novel disorder of the serine biosynthesis pathway.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acid Sequence; Base Sequence; Brain; Child, Preschool; DNA; Female; Frameshift Mutation; Glycine; Heterozygote; Humans; In Vitro Techniques; Infant; Infant, Newborn; Magnetic Resonance Imaging; Male; Models, Molecular; Molecular Sequence Data; Mutation, Missense; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Transaminases | 2007 |
The epidermis of scales in gecko lizards contains multiple forms of beta-keratins including basic glycine-proline-serine-rich proteins.
Topics: Amino Acid Sequence; Animals; beta-Keratins; Electrophoresis, Gel, Two-Dimensional; Epidermis; Foot; Glycine; Lizards; Molecular Sequence Data; Proline; Protein Conformation; Protein Isoforms; Serine | 2007 |
The effect of hinge mutations on effector binding and domain rotation in Escherichia coli D-3-phosphoglycerate dehydrogenase.
Topics: Asparagine; Chromatography, Gel; Escherichia coli; Glycine; Hydrogen Bonding; Kinetics; Models, Molecular; Mutation; Phosphoglycerate Dehydrogenase; Protein Binding; Protein Structure, Tertiary; Serine; Valine | 2007 |
Human KCNQ1 S140G mutation is associated with atrioventricular blocks.
Topics: Animals; Atrial Fibrillation; Atrioventricular Node; China; Chromans; Electrocardiography; Female; Genetic Predisposition to Disease; Glycine; Heart Block; Heart Rate; Heart Ventricles; Humans; Ion Channel Gating; KCNQ1 Potassium Channel; Male; Mice; Mice, Transgenic; Mutation; Pedigree; Phenotype; Research Design; Reverse Transcriptase Polymerase Chain Reaction; Serine; Severity of Illness Index; Sulfonamides | 2007 |
Ser84 of human renin contributes to the biphasic pH dependence of the renin-angiotensinogen reaction.
Topics: Amino Acid Substitution; Angiotensinogen; Animals; Glycine; Humans; Hydrogen-Ion Concentration; Kinetics; Mice; Models, Biological; Rats; Renin; Serine; Sheep; Substrate Specificity | 2007 |
Remarkable enhancement in PLD activity from Streptoverticillium cinnamoneum by substituting serine residue into the GG/GS motif.
Topics: Amino Acid Motifs; Circular Dichroism; Glycine; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Serine; Streptomycetaceae | 2007 |
An N-terminal nucleotide-binding site in VDAC1: involvement in regulating mitochondrial function.
Topics: Adenosine Triphosphate; Alanine; Apoptosis; Binding Sites; Cell Line; Cell Proliferation; Cytosol; Glycine; Humans; Lysine; Mitochondria; Mitochondrial Membranes; Mutation; Permeability; Protein Structure, Tertiary; RNA Interference; RNA, Small Interfering; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Time Factors; Transfection; Voltage-Dependent Anion Channel 1 | 2007 |
Effects of antipsychotic treatments and D-serine supplementation on the electrophysiological activation of midbrain dopamine neurons induced by the noncompetitive NMDA antagonist MK 801.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Dizocilpine Maleate; Dopamine; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Haloperidol; Male; Mesencephalon; Microelectrodes; Neurons; Olanzapine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine | 2007 |
Lrrk2-associated parkinsonism is a major cause of disease in Northern Spain.
Topics: Adult; Aged; Arginine; DNA Mutational Analysis; Family Health; Female; Genetic Predisposition to Disease; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinsonian Disorders; Protein Serine-Threonine Kinases; Serine; Spain | 2007 |
Beta-keratins of differentiating epidermis of snake comprise glycine-proline-serine-rich proteins with an avian-like gene organization.
Topics: Amino Acid Sequence; Animals; Base Sequence; beta-Keratins; Birds; Cell Differentiation; Colubridae; Epidermal Cells; Epidermis; Glycine; Molecular Sequence Data; Proline; Serine | 2007 |
Raman crystallographic studies of the intermediates formed by Ser130Gly SHV, a beta-lactamase that confers resistance to clinical inhibitors.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Clavulanic Acid; Crystallography, X-Ray; Enzyme Inhibitors; Glycine; Penicillanic Acid; Serine; Spectrum Analysis, Raman; Stereoisomerism; Tazobactam | 2007 |
Fusion of a recombinant antibody fragment with a homo-amino-acid polymer: effects on biophysical properties and prolonged plasma half-life.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Base Sequence; Circular Dichroism; Female; Glycine; Half-Life; Immunoglobulin Fab Fragments; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Plasma; Polymers; Receptor, ErbB-2; Recombinant Fusion Proteins; Serine; Trastuzumab | 2007 |
Frequency of the LRRK2 G2019S mutation in siblings with Parkinson's disease.
Topics: Aged; DNA Mutational Analysis; Europe; Family Health; Female; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine; Siblings | 2007 |
A new type of plasma prekallikrein deficiency associated with homozygosity for Gly104Arg and Asn124Ser in apple domain 2 of the heavy-chain region.
Topics: Amino Acid Substitution; Arginine; Asparagine; Base Sequence; Blotting, Western; DNA Primers; Female; Glycine; Homozygote; Humans; Male; Pedigree; Polymerase Chain Reaction; Prekallikrein; Serine | 2007 |
Comparison of L-monosodium glutamate and L-amino acid taste in rats.
Topics: Amino Acids; Animals; Arginine; Avoidance Learning; Dose-Response Relationship, Drug; Glycine; Isomerism; Male; Perception; Proline; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Serine; Signal Transduction; Sodium Glutamate; Taste; Taste Buds; Taste Threshold; Visceral Afferents | 2007 |
Gly111Ser mutation in CD8A gene causing CD8 immunodeficiency is found in Spanish Gypsies.
Topics: Adolescent; CD8 Antigens; DNA Mutational Analysis; Female; Glycine; Haplotypes; Humans; Immunologic Deficiency Syndromes; Male; Mutation; Pedigree; Roma; Serine; Spain | 2008 |
In vitro and in vivo pharmacological profile of AS057278, a selective d-amino acid oxidase inhibitor with potential anti-psychotic properties.
Topics: Amino Acid Oxidoreductases; Animals; Antipsychotic Agents; Cell Line; Cerebral Cortex; Colorimetry; D-Aspartate Oxidase; Enzyme Inhibitors; Escherichia coli; Glycine; Hallucinogens; Injections, Intravenous; Male; Mesencephalon; Motor Activity; Phencyclidine; Plasmids; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Reflex, Startle; Serine | 2008 |
Contribution of endogenous glycine and d-serine to excitotoxic and ischemic cell death in rat cerebrocortical slice cultures.
Topics: Animals; Animals, Newborn; Cell Death; Cell Survival; Cerebral Cortex; Excitatory Amino Acid Agonists; Glucose; Glycine; In Vitro Techniques; Ischemia; N-Methylaspartate; Oxygen; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine | 2007 |
No association between the DRD3 Ser9Gly polymorphism and schizophrenia.
Topics: Adult; Antipsychotic Agents; Case-Control Studies; Diagnostic and Statistical Manual of Mental Disorders; Family; Female; Gene Frequency; Genetic Linkage; Genetic Markers; Genetic Predisposition to Disease; Genotype; Glycine; Haplotypes; Homozygote; Humans; Male; Pedigree; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales; Receptors, Dopamine D3; Schizophrenia; Serine; White People | 2008 |
Dominant-negative inhibition of M-like potassium conductances in hair cells of the mouse inner ear.
Topics: Animals; Animals, Newborn; Cells, Cultured; Ear, Inner; Electric Stimulation; Embryo, Mammalian; Gene Expression; Gene Expression Regulation, Developmental; Genetic Vectors; Glycine; Hair Cells, Auditory, Inner; Humans; KCNQ Potassium Channels; Membrane Potentials; Mice; Mutation; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Saccule and Utricle; Serine; Transfection | 2007 |
Ionotropic glutamate-like receptor delta2 binds D-serine and glycine.
Topics: Animals; Binding Sites; Glycine; Kinetics; Ligands; Mice; Mice, Knockout; Models, Molecular; Protein Binding; Protein Conformation; Receptors, Glutamate; Serine; X-Ray Diffraction | 2007 |
Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin.
Topics: Amino Acid Substitution; Asparagine; Bacterial Proteins; Binding Sites; Cadherins; Calorimetry; Genetic Engineering; Genetic Variation; Glycine; Humans; Kinetics; Listeria monocytogenes; Models, Molecular; Protein Binding; Protein Conformation; Recombinant Proteins; Serine; Thermodynamics; Tyrosine | 2007 |
The G2019S LRRK2 mutation is uncommon amongst Greek patients with sporadic Parkinson's disease.
Topics: Aged; Aged, 80 and over; Amino Acid Substitution; Cohort Studies; Female; Glycine; Greece; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine | 2007 |
Compound heterozygosity of novel missense mutations (Ser45 --> Gly, Cys278 --> Arg) in the lipoprotein lipase gene in a newborn Korean infant.
Topics: Arginine; Cysteine; Female; Glycine; Heterozygote; Humans; Infant, Newborn; Infant, Small for Gestational Age; Korea; Lipoprotein Lipase; Male; Mutation, Missense; Pedigree; Serine | 2008 |
Metabolic engineering for betaine accumulation in microbes and plants.
Topics: Arabidopsis; Bacterial Proteins; Base Sequence; Betaine; Choline; Cyanobacteria; Escherichia coli; Gene Expression; Glycine; Methylation; Molecular Sequence Data; Oxidation-Reduction; Phosphoglycerate Dehydrogenase; Phosphorylation; Plants, Genetically Modified; Serine; Water-Electrolyte Balance | 2007 |
Molecular cloning and characterization of hemoglobin alpha and beta chains from plateau pika (Ochotona curzoniae) living at high altitude.
Topics: Adaptation, Physiological; Altitude; Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Base Sequence; Cloning, Molecular; Codon, Initiator; Codon, Terminator; Conserved Sequence; DNA Primers; DNA, Complementary; Glycine; Hemoglobin A; Hemoglobins; Humans; Lagomorpha; Molecular Sequence Data; Phenylalanine; Phylogeny; Polymerase Chain Reaction; Serine; Valine | 2007 |
Fibrinogen Leipzig II (gamma351Gly-->Ser and gamma82Ala-->Gly): hypodysfibrinogenaemia due to two independent amino acid substitutions within the same polypeptide chain.
Topics: Adult; Afibrinogenemia; Alanine; Fibrinogen; Glycine; Haplotypes; Hemorrhage; Heterozygote; Humans; Male; Models, Genetic; Mutation; Serine; Spectrometry, Mass, Electrospray Ionization; Time Factors | 2007 |
The G2019S LRRK2 mutation in Brazilian patients with Parkinson's disease: phenotype in monozygotic twins.
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Brazil; Diseases in Twins; Female; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Phenotype; Protein Serine-Threonine Kinases; Serine; Twins, Monozygotic | 2008 |
Aggregate formation of mutant protein kinase C gamma found in spinocerebellar ataxia type 14 impairs ubiquitin-proteasome system and induces endoplasmic reticulum stress.
Topics: Animals; Aspartic Acid; Caspases; Cell Death; CHO Cells; Cricetinae; Cricetulus; Endoplasmic Reticulum; Glycine; Green Fluorescent Proteins; Humans; Immunoprecipitation; Mutation; Proline; Proteasome Endopeptidase Complex; Protein Kinase C; Protein Processing, Post-Translational; Serine; Stress, Physiological; Time Factors; Transfection; Ubiquitin | 2007 |
Competitive inhibition of amino acid uptake suppresses chlamydial growth: involvement of the chlamydial amino acid transporter BrnQ.
Topics: Amino Acid Transport Systems; Amino Acids; Bacterial Proteins; Biological Transport; Cell Survival; Chlamydia; Chromatography, High Pressure Liquid; Cycloheximide; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Glycine; HeLa Cells; Humans; Isoleucine; Leucine; Methionine; Microscopy, Confocal; Microscopy, Electron, Transmission; Oligonucleotide Array Sequence Analysis; Phenylalanine; Reverse Transcriptase Polymerase Chain Reaction; Serine; Sirolimus; Threonine | 2008 |
Anchoring TRP to the INAD macromolecular complex requires the last 14 residues in its carboxyl terminus.
Topics: Animals; Drosophila; Drosophila Proteins; Eye Proteins; Glycine; Leucine; Macromolecular Substances; Mutagenesis, Site-Directed; Peptide Fragments; Phospholipase C beta; Phosphorylation; Photoreceptor Cells, Invertebrate; Protein Kinase C; Protein Structure, Tertiary; Serine; Transient Receptor Potential Channels; Tryptophan; Vision, Ocular; Voltage-Dependent Anion Channels | 2008 |
Multiple variants of the DRD3, but not BDNF gene, influence age-at-onset of schizophrenia.
Topics: Age of Onset; Brain-Derived Neurotrophic Factor; Female; Genetic Variation; Glycine; Humans; Male; Receptors, Dopamine D3; Schizophrenia; Serine | 2007 |
Functional and structural features of the oxyanion hole in a thermophilic esterase from Alicyclobacillus acidocaldarius.
Topics: Binding Sites; Carboxylic Ester Hydrolases; Catalysis; Crystallography, X-Ray; Enzyme Stability; Glycine; Gram-Positive Endospore-Forming Rods; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Models, Molecular; Mutation; Protein Binding; Protein Structure, Secondary; Serine; Substrate Specificity; Temperature; Water; X-Ray Diffraction | 2008 |
Mutation adjacent to the active site tyrosine can enhance DNA cleavage and cell killing by the TOPRIM Gly to Ser mutant of bacterial topoisomerase I.
Topics: Amino Acid Motifs; Amino Acid Substitution; Binding Sites; DNA; DNA Topoisomerases, Type I; Escherichia coli; Glycine; Magnesium; Methionine; Mutation; Phenotype; Serine; SOS Response, Genetics; Tyrosine; Valine; Yersinia pestis | 2008 |
Processing of N-terminal unnatural amino acids in recombinant human interferon-beta in Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Base Sequence; Binding Sites; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamic Acid; Glycine; Histidine; Humans; Interferon Type I; Molecular Sequence Data; Protein Engineering; Recombinant Proteins; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 2008 |
The conversion of glycine into serine in the intact rat.
Topics: Animals; Fabaceae; Glycine; Rats; Serine | 1949 |
Distribution of C14 in glycine and serine of liver protein following the administration of labeled glycine.
Topics: Amino Acids; Fabaceae; Glycine; Liver; Radioisotopes; Serine | 1949 |
The biological formation of serine from glycine.
Topics: Glycine; Serine | 1949 |
Regulation of betaine synthesis by precursor supply and choline monooxygenase expression in Amaranthus tricolor.
Topics: Amaranthus; Antisense Elements (Genetics); Arabidopsis; Betaine; Carbon Dioxide; Codon, Initiator; Ethanolamine; Gene Expression; Genes, Reporter; Genome, Plant; Glucuronidase; Glycine; Glycine Decarboxylase Complex; Isoniazid; Oxygenases; Plants, Genetically Modified; Promoter Regions, Genetic; Serine; Sodium Chloride | 2007 |
Familial amyotrophic lateral sclerosis with Gly93Ser mutation in Cu/Zn superoxide dismutase: a clinical and neuropathological study.
Topics: Adult; Amyotrophic Lateral Sclerosis; Central Nervous System; Family Health; Female; Glycine; Humans; Mutation; Serine; Superoxide Dismutase | 2008 |
RET Gly691Ser mutation is associated with primary vesicoureteral reflux in the French-Canadian population from Quebec.
Topics: Amino Acid Sequence; Glycine; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins c-ret; Quebec; Sequence Homology, Amino Acid; Serine; Signal Transduction; Vesico-Ureteral Reflux | 2008 |
The Ser9Gly polymorphism of the dopamine D3 receptor gene and risk of schizophrenia: an association study and a large meta-analysis.
Topics: Adult; Alleles; Case-Control Studies; China; Female; Gene Frequency; Genetic Predisposition to Disease; Glycine; Humans; Male; Meta-Analysis as Topic; Middle Aged; Polymorphism, Genetic; Receptors, Dopamine D3; Risk; Schizophrenia; Serine | 2008 |
Reappraisal of the role of the DRD3 gene in essential tremor.
Topics: Aged; Alleles; Essential Tremor; Female; Gene Frequency; Genetic Linkage; Genotype; Glycine; Humans; Linkage Disequilibrium; Male; Middle Aged; Pedigree; Polymorphism, Genetic; Receptors, Dopamine D3; Serine | 2008 |
The dopamine D(3) receptor Ser9Gly polymorphism modulates prepulse inhibition of the acoustic startle reflex.
Topics: Acoustic Stimulation; Adult; Analysis of Variance; Chi-Square Distribution; Chromosome Mapping; Electromyography; Genotype; Glycine; Humans; Inhibition, Psychological; Male; Polymorphism, Genetic; Psychophysics; Reaction Time; Receptors, Dopamine D3; Reflex, Acoustic; Reflex, Startle; Serine | 2008 |
Does the RET variant G691S influence the features of sporadic medullary thyroid carcinoma?
Topics: Adolescent; Adult; Age of Onset; Aged; Carcinoma, Medullary; Case-Control Studies; Female; Genetic Variation; Glycine; Humans; Male; Middle Aged; Neoplasm Metastasis; Proto-Oncogene Mas; Proto-Oncogene Proteins c-ret; Retrospective Studies; Serine; Thyroid Neoplasms; Young Adult | 2008 |
The intrinsic contributions of tyrosine, serine, glycine and arginine to the affinity and specificity of antibodies.
Topics: Amino Acid Sequence; Antibodies; Antibody Affinity; Antibody Specificity; Arginine; Binding Sites, Antibody; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Glycine; Models, Molecular; Peptide Library; Protein Binding; Serine; Tyrosine | 2008 |
Lrrk2 R1441C parkinsonism is clinically similar to sporadic Parkinson disease.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Arginine; Cysteine; DNA Mutational Analysis; Female; Glycine; Haplotypes; Humans; Internationality; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Parkinson Disease; Parkinsonian Disorders; Protein Serine-Threonine Kinases; Serine | 2008 |
Screening for the LRRK2 G2019S and codon-1441 mutations in a pathological series of parkinsonian syndromes and frontotemporal lobar degeneration.
Topics: Dementia; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Genetic Testing; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mutation; Parkinsonian Disorders; Protein Serine-Threonine Kinases; Serine | 2008 |
The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2.
Topics: Analysis of Variance; Animals; Animals, Newborn; Benzodioxoles; Brain; Cell Cycle Proteins; Cells, Cultured; Enzyme Inhibitors; Glycine; HSP90 Heat-Shock Proteins; Humans; Immunoprecipitation; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mass Spectrometry; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Chaperones; Mutation; Neurons; Proteasome Endopeptidase Complex; Protein Binding; Protein Serine-Threonine Kinases; Purines; Serine; Silver Staining; Transfection | 2008 |
TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Amyotrophic Lateral Sclerosis; Brain; Child; Dementia; DNA Mutational Analysis; DNA-Binding Proteins; Family Health; Female; Glycine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Serine; Ubiquitin | 2008 |
Expression of D-serine and glycine transporters in the prefrontal cortex and cerebellum in schizophrenia.
Topics: Amino Acid Transport System A; Animals; Antipsychotic Agents; Blotting, Western; Cerebellum; Control Groups; Female; Gene Expression; Glutamates; Glycine; Glycine Plasma Membrane Transport Proteins; Humans; In Situ Hybridization; Male; Middle Aged; Neurons; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Schizophrenia; Serine; Synapses | 2008 |
Pathway selection to the axon depends on multiple targeting signals in NgCAM.
Topics: Amino Acid Sequence; Animals; Axons; Cell Adhesion Molecules, Neuron-Glia; Cell Polarity; Chickens; Dendrites; Dogs; Endocytosis; Epithelial Cells; Glycine; Molecular Sequence Data; Sequence Alignment; Serine; Signal Transduction; trans-Golgi Network | 2008 |
Glycine and D: -serine, but not D: -cycloserine, attenuate prepulse inhibition deficits induced by NMDA receptor antagonist MK-801.
Topics: Animals; Antimetabolites; Chromatography, High Pressure Liquid; Cycloserine; Data Interpretation, Statistical; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Injections, Intraperitoneal; Male; Mice; Microdialysis; Quinolones; Reflex, Startle; Serine | 2008 |
Lack of association between DRD3 gene polymorphism and response to clozapine in Turkish schizoprenia patients.
Topics: Antipsychotic Agents; Base Sequence; Case-Control Studies; Clozapine; DNA Primers; Glycine; Polymorphism, Genetic; Receptors, Dopamine D3; Schizophrenia; Serine; Turkey | 2009 |
Uncertain pathogenicity of MSH2 variants N127S and G322D challenges their classification.
Topics: Asparagine; Aspartic Acid; Biliary Tract Neoplasms; Blotting, Western; Colorectal Neoplasms, Hereditary Nonpolyposis; DNA Mismatch Repair; DNA-Binding Proteins; Endometrial Neoplasms; Female; Genetic Predisposition to Disease; Germ-Line Mutation; Glycine; Humans; Immunoprecipitation; MutS Homolog 2 Protein; Pancreatic Neoplasms; Serine; Uncertainty | 2008 |
The association of genotypic combination of the DRD3 and BDNF polymorphisms on the adhesio interthalamica and medial temporal lobe structures.
Topics: Adolescent; Adult; Brain-Derived Neurotrophic Factor; Dominance, Cerebral; Female; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Magnetic Resonance Imaging; Male; Methionine; Polymorphism, Genetic; Receptors, Dopamine D3; Schizophrenia; Serine; Temporal Lobe; Thalamus; Valine | 2008 |
Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study.
Topics: Age Factors; Age of Onset; Case-Control Studies; DNA Mutational Analysis; Family Health; Female; Genetic Predisposition to Disease; Genetic Testing; Genotype; Glycine; Humans; International Cooperation; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Parkinson Disease; Penetrance; Protein Serine-Threonine Kinases; Risk; Serine; Severity of Illness Index | 2008 |
LRRK2 Gly2019Ser penetrance in Arab-Berber patients from Tunisia: a case-control genetic study.
Topics: Age Factors; Case-Control Studies; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Parkinson Disease; Penetrance; Protein Serine-Threonine Kinases; Residence Characteristics; Serine; Tunisia | 2008 |
LRRK2: bridging the gap between sporadic and hereditary Parkinson's disease.
Topics: Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine | 2008 |
Crystallization and preliminary X-ray analysis of recombinant Glomerella cingulata cutinase.
Topics: Binding Sites; Carboxylic Ester Hydrolases; Crystallization; Escherichia coli; Glycine; Phyllachorales; Protein Binding; Protein Folding; Protein Structure, Secondary; Recombinant Proteins; Serine; X-Ray Diffraction | 2008 |
Mice with reduced NMDA receptor glycine affinity model some of the negative and cognitive symptoms of schizophrenia.
Topics: Animals; Behavior, Animal; Carrier Proteins; Clozapine; Disease Models, Animal; Glycine; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nerve Tissue Proteins; Phenotype; Quinolones; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Sarcosine; Schizophrenia; Schizophrenic Psychology; Serine; Social Behavior; Space Perception | 2008 |
Two mass-spectrometric techniques for quantifying serine enantiomers and glycine in cerebrospinal fluid: potential confounders and age-dependent ranges.
Topics: Adolescent; Adult; Cerebrospinal Fluid; Child; Child, Preschool; Glycine; Health; Humans; Infant; Infant, Newborn; Mass Spectrometry; Serine; Stereoisomerism | 2008 |
PGC-1alpha Gly482Ser polymorphism is associated with the plasma adiponectin level in type 2 diabetic men.
Topics: Adiponectin; Aged; Cells, Cultured; Diabetes Mellitus, Type 2; Female; Glycine; Heat-Shock Proteins; HeLa Cells; Humans; Linkage Disequilibrium; Male; Middle Aged; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Polymorphism, Single Nucleotide; Serine; Sex Characteristics; Transcription Factors; Transfection | 2008 |
Genetic screening for LRRK2 gene G2019S mutation in Parkinson's disease patients from Southern Italy.
Topics: Adult; Age of Onset; Aged; DNA Mutational Analysis; Female; Fluorodeoxyglucose F18; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Genotype; Glycine; Humans; Italy; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Protein Serine-Threonine Kinases; Serine; Young Adult | 2009 |
Molecular mechanism of ligand recognition by NR3 subtype glutamate receptors.
Topics: Amino Acid Sequence; Amino Acids, Cyclic; Computer Simulation; Drug Partial Agonism; Glycine; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Receptors, N-Methyl-D-Aspartate; Serine | 2008 |
Development of a temperature gradient focusing method for in situ extraterrestrial biomarker analysis.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Aspartic Acid; Biomarkers; Countercurrent Distribution; Electrophoresis, Microchip; Extraterrestrial Environment; Glutamic Acid; Glycine; Life; Mars; Serine; Soil; Space Flight; Stereoisomerism; Temperature; Valine | 2008 |
The G1556S-type tuberin variant suppresses tumor formation in tuberous sclerosis 2 mutant (Eker) rats despite its deficiency in mTOR inhibition.
Topics: Animals; Animals, Genetically Modified; Base Sequence; Cell Line; Glycine; Mutation; Protein Kinases; Rats; Serine; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2008 |
Importance of tyrosine residues of Bacillus stearothermophilus serine hydroxymethyltransferase in cofactor binding and L-allo-Thr cleavage.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Geobacillus stearothermophilus; Glycine; Glycine Hydroxymethyltransferase; Models, Molecular; Protein Binding; Pyridoxal Phosphate; Serine; Stereoisomerism; Tetrahydrofolates; Threonine; Tyrosine | 2008 |
Pharmacological stimulation of NMDA receptors via co-agonist site suppresses fMRI response to phencyclidine in the rat.
Topics: Animals; Benzamides; Binding Sites; Blood Volume; Brain; Dose-Response Relationship, Drug; Glycine; Glycine Plasma Membrane Transport Proteins; Injections, Intravenous; Magnetic Resonance Imaging; Male; Models, Theoretical; Phencyclidine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Time Factors | 2008 |
A clinical, neuropsychological and olfactory evaluation of a large family with LRRK2 mutations.
Topics: Aged; DNA Mutational Analysis; Family Health; Female; France; Genetic Predisposition to Disease; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Neuropsychological Tests; Olfaction Disorders; Parkinson Disease; Protein Serine-Threonine Kinases; Serine | 2009 |
LRRK2 gene G2019S mutation and SNPs [haplotypes] in subtypes of Parkinson's disease.
Topics: Age of Onset; Aged; Aged, 80 and over; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Glycine; Haplotypes; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Parkinson Disease; Polymorphism, Single Nucleotide; Protein Serine-Threonine Kinases; Serine; White People | 2009 |
Impact of the Gly573Ser substitution in TRPV3 on the development of allergic and pruritic dermatitis in mice.
Topics: Animals; Dermatitis; Glycine; Hypersensitivity; Immunoglobulin E; Ligands; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phenotype; Promoter Regions, Genetic; Pruritus; Serine; TRPV Cation Channels | 2009 |
CSF serine enantiomers and glycine in the study of neurologic and psychiatric disorders.
Topics: Animals; Cerebrospinal Fluid; Glycine; Humans; Mental Disorders; Nervous System Diseases; Serine; Stereoisomerism | 2008 |
Crystallographic study of G178S mutant of human proliferating cell nuclear antigen.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cloning, Molecular; Crystallization; Crystallography, X-Ray; Glycine; Humans; Molecular Sequence Data; Mutation; Proliferating Cell Nuclear Antigen; Saccharomyces cerevisiae; Serine | 2008 |
Genetic analysis for five LRRK2 mutations in a Sardinian parkinsonian population: importance of G2019S and R1441C mutations in sporadic Parkinson's disease patients.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Arginine; Cysteine; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Genotype; Glycine; Humans; Italy; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Population Groups; Protein Serine-Threonine Kinases; Serine; Tomography, Emission-Computed, Single-Photon | 2009 |
LRRK2 mutations in Basque patients with Parkinson's disease.
Topics: Arginine; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine; Spain | 2008 |
The conversion of formate and glycine to serine and glycogen in the intact rat.
Topics: Animals; Formates; Glycine; Glycogen; Rats; Serine | 1948 |
l-Serine induces sedative and hypnotic effects acting at GABA(A) receptors in neonatal chicks.
Topics: Acute Disease; Animals; Animals, Newborn; Chickens; Disease Models, Animal; Glycine; Hypnotics and Sedatives; Male; Picrotoxin; Receptors, GABA-A; Receptors, Glycine; Serine; Stress, Psychological | 2008 |
Mutant mice with reduced NMDA-NR1 glycine affinity or lack of D-amino acid oxidase function exhibit altered anxiety-like behaviors.
Topics: Animals; Antipsychotic Agents; Anxiety; Carrier Proteins; D-Amino-Acid Oxidase; Female; Glycine; Male; Maze Learning; Mice; Mice, Inbred C57BL; Motor Activity; Mutation; Nerve Tissue Proteins; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Social Behavior; Space Perception | 2009 |
The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study.
Topics: Age Factors; Aged; Aged, 80 and over; Female; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Penetrance; Protein Serine-Threonine Kinases; Random Allocation; Serine; Sex Factors | 2008 |
Unilateral pallidotomy in a patient with parkinsonism and G2019S LRRK2 mutation.
Topics: Female; Functional Laterality; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Middle Aged; Mutation; Pallidotomy; Parkinsonian Disorders; Protein Serine-Threonine Kinases; Serine | 2009 |
High-casein diet suppresses guanidinoacetic acid-induced hyperhomocysteinemia and potentiates the hypohomocysteinemic effect of serine in rats.
Topics: Animals; Caseins; Cysteine; Diet; Glycine; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rats; Rats, Wistar; Serine | 2008 |
L-Serine lowers while glycine increases blood pressure in chronic L-NAME-treated and spontaneously hypertensive rats.
Topics: Animals; Apamin; Blood Pressure; Charybdotoxin; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycine; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Potassium Channels, Calcium-Activated; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Serine; Threonine | 2008 |
The PPARGC1A Gly482Ser polymorphism is associated with left ventricular diastolic dysfunction in men.
Topics: Adult; Aged; Alleles; Cohort Studies; Female; Glycine; Heat-Shock Proteins; Humans; Male; Middle Aged; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Polymorphism, Genetic; Serine; Sex Characteristics; Transcription Factors; Ventricular Dysfunction, Left | 2008 |
Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of Type 2 diabetes: 2. Optimization of serine and threonine ether amino acid residues.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chemistry, Pharmaceutical; Crystallography, X-Ray; Cytochrome P-450 CYP2C9; Diabetes Mellitus, Type 2; Drug Design; Glycine; Glycogen Phosphorylase; Humans; Imides; Inhibitory Concentration 50; Liver; Models, Chemical; ortho-Aminobenzoates; Rats; Serine; Threonine | 2009 |
Association of the dopamine D3 receptor Ser9Gly and of the serotonin 2C receptor gene polymorphisms with tardive dyskinesia in Greeks with chronic schizophrenic disorder.
Topics: Amino Acid Substitution; Chronic Disease; Dyskinesias; Female; Genetic Predisposition to Disease; Glycine; Greece; Humans; Male; Polymorphism, Genetic; Receptor, Serotonin, 5-HT2C; Receptors, Dopamine D3; Schizophrenia; Serine; White People | 2009 |
Unique glycine-activated riboswitch linked to glycine-serine auxotrophy in SAR11.
Topics: Acetic Acid; Alphaproteobacteria; Base Sequence; Glucose; Glycine; Malate Synthase; Metabolic Networks and Pathways; Models, Biological; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Bacterial; Seawater; Serine | 2009 |
Aminoacyl-tRNA recognition by the FemXWv transferase for bacterial cell wall synthesis.
Topics: Alanine; Bacteria; Cell Wall; Glycine; Nitrogenous Group Transferases; RNA, Transfer, Ala; RNA, Transfer, Amino Acyl; Serine; Stereoisomerism; Substrate Specificity; Uridine Diphosphate N-Acetylmuramic Acid | 2009 |
Crystallization and preliminary X-ray analysis of FliJ, a cytoplasmic component of the flagellar type III protein-export apparatus from Salmonella sp.
Topics: Bacterial Proteins; Crystallography, X-Ray; Cytoplasm; Flagella; Glutathione; Glycine; Histidine; Mercury; Protein Structure, Tertiary; Salmonella; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; X-Ray Diffraction | 2009 |
Moderate dietary vitamin B-6 restriction raises plasma glycine and cystathionine concentrations while minimally affecting the rates of glycine turnover and glycine cleavage in healthy men and women.
Topics: Adult; Cystathionine; Diet; Female; Glycine; Humans; Male; Serine; Tetrahydrofolates; Vitamin B 6; Vitamin B 6 Deficiency; Young Adult | 2009 |
Multiple step pattern as a biomarker in Parkinson disease.
Topics: Aged; Analysis of Variance; Attention; Biomarkers; Female; Fixation, Ocular; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Memory; Middle Aged; Mutation; Neuropsychological Tests; Parkinson Disease; Photic Stimulation; Protein Serine-Threonine Kinases; Reaction Time; Saccades; Serine; Siblings | 2009 |
Structural basis of glyphosate resistance resulting from the double mutation Thr97 -> Ile and Pro101 -> Ser in 5-enolpyruvylshikimate-3-phosphate synthase from Escherichia coli.
Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Binding Sites; Crystallography, X-Ray; Drug Resistance, Bacterial; Enzyme Inhibitors; Escherichia coli; Glycine; Glyphosate; Isoleucine; Kinetics; Models, Chemical; Molecular Conformation; Mutation; Proline; Serine; Threonine | 2009 |
Genetic study of BDNF, DRD3, and their interaction in tardive dyskinesia.
Topics: Adult; Akathisia, Drug-Induced; Analysis of Variance; Brain-Derived Neurotrophic Factor; Chi-Square Distribution; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Male; Middle Aged; Polymorphism, Genetic; Receptors, Dopamine D3; Schizophrenia; Serine; Young Adult | 2009 |
Association analysis of glycine- and serine-related genes in a Japanese population of patients with schizophrenia.
Topics: Adult; Case-Control Studies; Chi-Square Distribution; D-Amino-Acid Oxidase; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Glycine; Glycine Hydroxymethyltransferase; Humans; Japan; Linkage Disequilibrium; Male; Middle Aged; Phosphoglycerate Dehydrogenase; Polymorphism, Single Nucleotide; Racemases and Epimerases; Schizophrenia; Serine; Young Adult | 2009 |
Essential role of one-carbon metabolism and Gcn4p and Bas1p transcriptional regulators during adaptation to anaerobic growth of Saccharomyces cerevisiae.
Topics: Basic-Leucine Zipper Transcription Factors; Cell Proliferation; Cell Wall; DNA-Binding Proteins; Gene Expression Regulation, Fungal; Genes, Reporter; Genotype; Glycine; Models, Biological; Mutation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Subcellular Fractions; Threonine; Trans-Activators; Transcription Factors; Transcription, Genetic | 2009 |
Role of {alpha}-subunit VISIT-DG sequence residues Ser-347 and Gly-351 in the catalytic sites of Escherichia coli ATP synthase.
Topics: 4-Chloro-7-nitrobenzofurazan; Amino Acid Sequence; Animals; ATP Synthetase Complexes; Base Sequence; Catalytic Domain; Dicyclohexylcarbodiimide; Dithiothreitol; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Glycine; Humans; Molecular Conformation; Molecular Sequence Data; Mutation; Protein Subunits; Sequence Alignment; Serine | 2009 |
A mathematical model gives insights into the effects of vitamin B-6 deficiency on 1-carbon and glutathione metabolism.
Topics: Biomarkers; Carbon; Glutathione; Glycine; Glycine Hydroxymethyltransferase; Models, Biological; Oxidative Stress; Serine; Vitamin B 6 Deficiency | 2009 |
[Genetics of atrial fibrillation].
Topics: Adolescent; Adult; Aged; Amino Acid Substitution; Atrial Fibrillation; Child; Child, Preschool; Female; G-Protein-Coupled Receptor Kinase 2; Genetic Testing; Glycine; Humans; Male; Middle Aged; Pedigree; Polymorphism, Genetic; Serine; Young Adult | 2009 |
Glycine transporter blockade ameliorates motor ataxia in a mouse model of spinocerebellar atrophy.
Topics: Animals; Binding Sites; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Glycine; Glycine Plasma Membrane Transport Proteins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Spinocerebellar Ataxias | 2009 |
Genetic variants of D2 but not D3 or D4 dopamine receptor gene are associated with rapid onset and poor prognosis of methamphetamine psychosis.
Topics: Adult; Case-Control Studies; Central Nervous System Stimulants; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glycine; Humans; Male; Methamphetamine; Middle Aged; Minisatellite Repeats; Prognosis; Psychoses, Substance-Induced; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Dopamine D4; Serine; Statistics, Nonparametric | 2009 |
Surface aggregation of urinary proteins and aspartic Acid-rich peptides on the faces of calcium oxalate monohydrate investigated by in situ force microscopy.
Topics: Aspartic Acid; Calcium Oxalate; Crystallization; Glycine; Humans; Kinetics; Microscopy, Atomic Force; Mucoproteins; Osteopontin; Peptides; Serine; Urinary Calculi; Uromodulin | 2009 |
The increased incidence of the RET p.Gly691Ser variant in French-Canadian vesicoureteric reflux patients is not replicated by a larger study in Ireland.
Topics: Alleles; Amino Acid Substitution; Canada; Case-Control Studies; Female; France; Gene Frequency; Genetic Predisposition to Disease; Glycine; Humans; Incidence; Ireland; Male; Mutation; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins c-ret; Reproducibility of Results; Serine; Siblings; Urogenital Abnormalities; Vesico-Ureteral Reflux; White People | 2009 |
Release of endogenous amino acids from the hippocampus and brain stem from developing and adult mice in ischemia.
Topics: Aging; Alanine; Animals; Aspartic Acid; Brain Ischemia; Brain Stem; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Male; Mice; Potassium; Serine; Taurine; Threonine | 2009 |
The G314S KCNQ1 mutation exerts a dominant-negative effect on expression of KCNQ1 channels in oocytes.
Topics: Action Potentials; Amino Acid Sequence; Animals; Electrophysiological Phenomena; Genes, Dominant; Glycine; Humans; KCNQ1 Potassium Channel; Long QT Syndrome; Molecular Sequence Data; Mutation, Missense; Oocytes; Serine; Xenopus | 2009 |
Motor complications in patients form the German Competence Network on Parkinson's disease and the DRD3 Ser9Gly polymorphism.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Community Networks; Dyskinesia, Drug-Induced; Female; Genetic Predisposition to Disease; Germany; Glycine; Humans; Male; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Receptors, Dopamine D3; Regression Analysis; Serine | 2009 |
Early Tau pathology involving the septo-hippocampal pathway in a Tau transgenic model: relevance to Alzheimer's disease.
Topics: Age Factors; Alzheimer Disease; Animals; Brain Mapping; Disease Models, Animal; Glycine; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neural Pathways; Proline; Septum of Brain; Serine; Stilbamidines; tau Proteins; Valine | 2009 |
Increased hydrophobicity at the N terminus/membrane interface impairs gating of the severe combined immunodeficiency-related ORAI1 mutant.
Topics: Amino Acid Substitution; Calcium Channels; Cell Line; Cell Membrane; Cloning, Molecular; Computational Biology; Fluorescence Resonance Energy Transfer; Glycine; Humans; Kidney; Kinetics; Mutagenesis, Site-Directed; ORAI1 Protein; Restriction Mapping; Serine; Severe Combined Immunodeficiency; Transfection | 2009 |
Antinociceptive effects of systemic lidocaine: involvement of the spinal glycinergic system.
Topics: Analgesics; Animals; Binding Sites; Glycine; Glycine Agents; Lidocaine; Organophosphonates; Pain; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Spinal Cord; Substrate Specificity; Synaptic Transmission | 2009 |
Hepatic cystathionine beta-synthase activity does not increase in response to methionine supplementation in rats fed a low casein diet: association with plasma homocysteine concentrations.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Caseins; Cystathionine beta-Synthase; Cysteine; Dietary Proteins; Dietary Supplements; Dose-Response Relationship, Drug; Energy Intake; Glycine; Homocysteine; Liver; Male; Methionine; Organ Size; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Weight Gain | 2009 |
Tardive dyskinesia and DRD3, HTR2A and HTR2C gene polymorphisms in Russian psychiatric inpatients from Siberia.
Topics: Adult; Aged; Akathisia, Drug-Induced; Chlorpromazine; Cross-Sectional Studies; Cystine; Disability Evaluation; Extremities; Face; Female; Gene Frequency; Genotype; Glycine; Humans; Male; Middle Aged; Models, Statistical; Mouth; Pharmacogenetics; Polymorphism, Genetic; Psychiatric Status Rating Scales; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Dopamine D3; Schizophrenia; Serine; Severity of Illness Index; Siberia | 2009 |
NMR conformational and dynamic consequences of a gly to ser substitution in an osteogenesis imperfecta collagen model peptide.
Topics: Amino Acid Sequence; Amino Acid Substitution; Collagen; Glycine; Hydrogen; Magnetic Resonance Spectroscopy; Models, Biological; Models, Molecular; Molecular Sequence Data; Osteogenesis Imperfecta; Peptides; Protein Conformation; Serine; Temperature | 2009 |
Interference with cellular differentiation by D-serine through antagonism at N-methyl-D-aspartate receptors composed of NR1 and NR3A subunits in chondrocytes.
Topics: Alkaline Phosphatase; Animals; Animals, Newborn; Calcification, Physiologic; Calcium; Cell Differentiation; Chlorocebus aethiops; Chondrocytes; Chondrogenesis; Core Binding Factor Alpha 1 Subunit; COS Cells; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gestational Age; Glycine; Humans; Membrane Glycoproteins; Metatarsal Bones; Mice; Mice, Knockout; N-Methylaspartate; Osteopontin; Racemases and Epimerases; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Serine; Time Factors; Tissue Culture Techniques; Transfection | 2009 |
DRD3 Ser9Gly polymorphism is related to thermal pain perception and modulation in chronic widespread pain patients and healthy controls.
Topics: Adult; Amino Acid Sequence; Chronic Disease; DNA Mutational Analysis; Dopamine; Female; Fibromyalgia; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Glycine; Humans; Hyperalgesia; Limbic System; Male; Middle Aged; Neural Inhibition; Pain Measurement; Pain Threshold; Pain, Intractable; Polymorphism, Genetic; Receptors, Dopamine D3; Serine | 2009 |
Enantiospecific adsorption of amino acids on hydroxylated quartz (0001).
Topics: Adsorption; Alanine; Amino Acids; Cysteine; Glycine; Hydrogen Bonding; Hydroxylation; Models, Molecular; Molecular Conformation; Quantum Theory; Quartz; Serine; Stereoisomerism | 2009 |
Association of 1704G/T and G82S polymorphisms in the receptor for advanced glycation end products gene with diabetic retinopathy in Chinese population.
Topics: Adult; Aged; Amino Acid Substitution; Case-Control Studies; China; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Gene Frequency; Genetics, Population; Genotype; Glycine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serine | 2009 |
Effects of inhibitory amino acids on adenosine release in the mouse hippocampus.
Topics: Adenosine; Aging; Animals; Animals, Newborn; beta-Alanine; Excitatory Amino Acid Antagonists; Female; Glycine; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Oxygen; Serine | 2008 |
Glycine and urea kinetics in nonalcoholic steatohepatitis in human: effect of intralipid infusion.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Case-Control Studies; Cystathionine; Fasting; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Fatty Liver; Female; Glutathione; Glycine; Humans; Infusions, Intravenous; Kinetics; Liver; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Postprandial Period; Serine; Urea; Young Adult | 2009 |
Glycine and L-serine crystalline perhydrates.
Topics: Crystallization; Glycine; Hydrogen Bonding; Hydrogen Peroxide; Models, Molecular; Serine; Spectroscopy, Fourier Transform Infrared; Stereoisomerism | 2009 |
Characterization of Plasmodium falciparum serine hydroxymethyltransferase-A potential antimalarial target.
Topics: Animals; Chromatography, Affinity; Cloning, Molecular; DNA, Complementary; DNA, Protozoan; Escherichia coli; Gene Expression; Glycine; Glycine Hydroxymethyltransferase; Kinetics; Plasmodium falciparum; Recombinant Fusion Proteins; Serine; Spectrum Analysis; Tetrahydrofolates | 2009 |
Antagonism of metabotropic glutamate receptor 4 receptors by (RS)-alpha-cyclopropyl-4-phosphonophenylglycine alters the taste of amino acids in rats.
Topics: Amino Acids; Animals; Arginine; Avoidance Learning; Conditioning, Classical; Excitatory Amino Acid Antagonists; Glycine; Male; Neuropsychological Tests; Physical Stimulation; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Serine; Sodium Glutamate; Taste Perception | 2009 |
Genetic variants of beta(1)-adrenoceptor gene polymorphisms (Ser49Gly and Arg389Gly) and essential hypertension in a south Indian Tamil population.
Topics: Adult; Amino Acid Substitution; Arginine; Case-Control Studies; Female; Gene Frequency; Genetics, Population; Genotype; Glycine; Humans; Hypertension; India; Male; Middle Aged; Polymorphism, Single Nucleotide; Receptors, Adrenergic, beta-1; Serine | 2009 |
Elucidating the genetics and pathology of Perry syndrome.
Topics: Adult; Age of Onset; Aged; Animals; Brain; Chlorocebus aethiops; COS Cells; Depression; DNA-Binding Proteins; Dynactin Complex; Family Health; Female; Glycine; Humans; Hypoventilation; Male; Microtubule-Associated Proteins; Middle Aged; Models, Molecular; Mutation; Parkinsonian Disorders; Serine; Transfection | 2010 |
Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila.
Topics: Amino Acid Substitution; Animals; Animals, Genetically Modified; Dopamine; Drosophila; Drosophila Proteins; Genetic Variation; Glycine; Humans; Nerve Degeneration; Protein Serine-Threonine Kinases; Serine; Ubiquitin-Protein Ligases | 2009 |
Genetic loss of D-amino acid oxidase activity reverses schizophrenia-like phenotypes in mice.
Topics: Animals; Arginine; Asparagine; Aspartic Acid; Behavior, Animal; Binding Sites; Carrier Proteins; D-Amino-Acid Oxidase; Female; Glycine; Male; Mice; Mutation; Nerve Tissue Proteins; Nervous System; Phenotype; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Serine; Social Behavior; Stereoisomerism | 2010 |
Intraperiaqueductal gray glycine and D-serine exert dual effects on rostral ventromedial medulla ON- and OFF-cell activity and thermoceptive threshold in the rat.
Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; Drug Combinations; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Neural Pathways; Neurons; Pain Measurement; Pain Threshold; Periaqueductal Gray; Rats; Rats, Wistar; Reaction Time; Serine; Strychnine; Tail | 2009 |
AMINO ACID COMPOSITION OF HIGHLY PURIFIED VIRAL PARTICLES OF INFLUENZA A AND B.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Humans; Influenza, Human; Isoleucine; Leucine; Lysine; Methionine; Orthomyxoviridae; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine; Virion | 1947 |
A transition path ensemble study reveals a linchpin role for Mg(2+) during rate-limiting ADP release from protein kinase A.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Algorithms; Binding Sites; Cations, Divalent; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Glycine; Kinetics; Magnesium; Models, Molecular; Serine; Thermodynamics; Threonine | 2009 |
Mutations in the conserved glycine and serine of the MutS ABC signature motif affect nucleotide exchange, kinetics of sliding clamp release of mismatch and mismatch repair.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; ATP-Binding Cassette Transporters; DNA Mismatch Repair; Escherichia coli Proteins; Glycine; Models, Molecular; Molecular Sequence Data; Mutation; MutS DNA Mismatch-Binding Protein; Nucleotides; Serine | 2010 |
d-Serine enhancement of NMDA receptor-mediated calcium increases in rat retinal ganglion cells.
Topics: Animals; Animals, Newborn; Calcium; Cells, Cultured; D-Amino-Acid Oxidase; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glycine; In Vitro Techniques; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Ganglion Cells; Serine; Time Factors | 2010 |
Familial amyotrophic lateral sclerosis with a novel G85S mutation of superoxide dismutase 1 gene: clinical features of lower motor neuron disease.
Topics: Adult; Amyotrophic Lateral Sclerosis; Fatal Outcome; Female; Glycine; Humans; Male; Motor Neuron Disease; Mutation; Pedigree; Serine; Superoxide Dismutase; Superoxide Dismutase-1 | 2010 |
Long-term potentiation depends on release of D-serine from astrocytes.
Topics: Animals; Astrocytes; Calcium; Exocytosis; Glycine; Hippocampus; Long-Term Potentiation; Male; Memory; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine; Synapses | 2010 |
Glycine oxidation and conversion into amino acids in Saccharomyces cerevisiae and Candida albicans.
Topics: Candida albicans; Glycine; Oxidation-Reduction; Saccharomyces cerevisiae; Serine; Threonine | 2010 |
A weak link in metabolism: the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis.
Topics: Adult; Animals; Carbon Isotopes; Collagen; Diet; Energy Metabolism; Glutathione; Glycine; Glycine Hydroxymethyltransferase; Glyoxylates; Humans; Molecular Structure; Porphyrins; Serine | 2009 |
Alternative route for glyoxylate consumption during growth on two-carbon compounds by Methylobacterium extorquens AM1.
Topics: Bacterial Proteins; Carbon; Carbon Isotopes; Ethylamines; Gene Deletion; Gene Expression Profiling; Glycine; Glyoxylates; Metabolic Networks and Pathways; Metabolome; Methylobacterium extorquens; Oligonucleotide Array Sequence Analysis; Oxo-Acid-Lyases; Serine; Tetrahydrofolates | 2010 |
Structural basis for inverting the enantioselectivity of arylmalonate decarboxylase revealed by the structural analysis of the Gly74Cys/Cys188Ser mutant in the liganded form.
Topics: Amino Acid Substitution; Bordetella bronchiseptica; Carboxy-Lyases; Catalytic Domain; Crystallization; Crystallography, X-Ray; Cysteine; Glycine; Ligands; Protein Binding; Protein Conformation; Protons; Serine; Stereoisomerism | 2010 |
N-arachidonoyl glycine, an endogenous lipid that acts as a vasorelaxant via nitric oxide and large conductance calcium-activated potassium channels.
Topics: Animals; Arachidonic Acids; Drug Interactions; Endothelium, Vascular; gamma-Aminobutyric Acid; Glycine; Large-Conductance Calcium-Activated Potassium Channels; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptides; Pertussis Toxin; Rats; Rats, Wistar; Serine; Vasodilation | 2010 |
Metal cation dependence of interactions with amino acids: bond energies of Rb+ to Gly, Ser, Thr, and Pro.
Topics: Amino Acids; Cations; Glycine; Proline; Rubidium; Serine; Tandem Mass Spectrometry; Thermodynamics; Threonine; Xenon | 2010 |
Anaerobic sulfatase-maturating enzyme--a mechanistic link with glycyl radical-activating enzymes?
Topics: Alanine; Anaerobiosis; Binding Sites; Catalysis; Cysteine; Electron Spin Resonance Spectroscopy; Eukaryota; Glycine; Iron-Sulfur Proteins; Oxidation-Reduction; S-Adenosylmethionine; Serine; Substrate Specificity; Sulfatases | 2010 |
Involvement of the cerebral cortex in Parkinson disease linked with G2019S LRRK2 mutation without cognitive impairment.
Topics: Aged; Aged, 80 and over; alpha-Synuclein; Cerebral Cortex; Cognition Disorders; Electrophoresis, Gel, Two-Dimensional; Female; Glial Fibrillary Acidic Protein; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Malondialdehyde; Mass Spectrometry; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serine; Statistics, Nonparametric | 2010 |
D-serine is distributed in neurons in the brain of the sea lamprey.
Topics: Animals; Brain; gamma-Aminobutyric Acid; Glycine; Neurons; Petromyzon; Serine | 2010 |
Ser9Gly polymorphism of the DRD3 gene is associated with worse premorbid social functioning and an earlier age of onset in female but not male schizophrenic patients.
Topics: Adolescent; Adult; Age of Onset; Child; Female; Gene Frequency; Genome-Wide Association Study; Glycine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Receptors, Dopamine D3; Schizophrenia; Schizophrenic Psychology; Serine; Sex Characteristics; Social Behavior; Young Adult | 2010 |
Glycine transport accounts for the differential role of glycine vs. D-serine at NMDA receptor coagonist sites in the salamander retina.
Topics: Ambystoma; Animals; Binding, Competitive; Glycine; Patch-Clamp Techniques; Protein Isoforms; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Ganglion Cells; Serine | 2010 |
Temperamentsxgenes in bipolar I and bipolar II disorder patients.
Topics: Bipolar Disorder; DNA Mutational Analysis; Exploratory Behavior; Female; Genotype; Glycine; Humans; Male; Personality Inventory; Polymorphism, Genetic; Psychiatric Status Rating Scales; Receptors, Dopamine D3; Regression Analysis; Serine; Taiwan; Temperament | 2010 |
The CD226 Gly307Ser gene polymorphism is associated with severity of psoriasis.
Topics: Adult; Age of Onset; Alleles; Antigens, Differentiation, T-Lymphocyte; Autoimmunity; Cohort Studies; Female; Gene Frequency; Genotype; Glycine; Humans; Male; Polymorphism, Genetic; Psoriasis; Serine | 2010 |
Computational modelling of amino acid transfer interactions in the placenta.
Topics: Alanine; Amino Acid Transport Systems; Amino Acids; Biological Transport; Computer Simulation; Female; Fetus; Glycine; Humans; Kinetics; Maternal-Fetal Exchange; Placenta; Pregnancy; Serine; Trophoblasts | 2010 |
Hydrophilic linkers and polar contacts affect aggregation of FG repeat peptides.
Topics: Glycine; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Dynamics Simulation; Mutation; Peptides; Phenylalanine; Protein Multimerization; Protein Structure, Quaternary; Protein Structure, Secondary; Serine; Solvents; Water | 2010 |
Changes in sulphur metabolism of grey poplar (Populus x canescens) leaves during salt stress: a metabolic link to photorespiration.
Topics: Adaptation, Physiological; Ammonia; Chlorophyll; Glycine; Nitrates; Photosynthesis; Plant Leaves; Populus; Serine; Sodium Chloride; Stress, Physiological; Sulfur | 2010 |
Electron attachment to amino acid clusters in helium nanodroplets: glycine, alanine, and serine.
Topics: Alanine; Electrons; Glycine; Helium; Nanostructures; Serine; Temperature | 2010 |
Characterization of antimicrobial resistance of recent Salmonella enterica serovar Gallinarum isolates from chickens in South Korea.
Topics: Amino Acid Substitution; Animals; Anti-Bacterial Agents; Chickens; DNA Gyrase; DNA Primers; Drug Resistance, Bacterial; Glycine; Microbial Sensitivity Tests; Phenotype; Poultry Diseases; Quinolones; Republic of Korea; Salmonella enterica; Salmonella Infections, Animal; Serine; Sulfamethoxazole; Tyrosine | 2010 |
Familial ALS with G298S mutation in TARDBP: a comparison of CSF tau protein levels with those in sporadic ALS.
Topics: Amino Acid Substitution; Amyotrophic Lateral Sclerosis; DNA-Binding Proteins; Glycine; Humans; Male; Middle Aged; Mutation, Missense; Pedigree; Serine | 2010 |
Glycine transporter (GlyT1) inhibitors with reduced residence time increase prepulse inhibition without inducing hyperlocomotion in DBA/2 mice.
Topics: Animals; Glycine; Glycine Plasma Membrane Transport Proteins; Male; Mice; Mice, Inbred DBA; Motor Activity; Neural Inhibition; Sarcosine; Serine; Strychnine; Time Factors | 2010 |
Purification and biochemical characterization of Mur ligases from Staphylococcus aureus.
Topics: Adenosine Triphosphate; Alanine; Bacterial Proteins; Diaminopimelic Acid; Escherichia coli; Genetic Complementation Test; Glycine; Hydrogen-Ion Concentration; Kinetics; Ligases; Mutation; Oligopeptides; Peptidoglycan; Recombinant Proteins; Serine; Staphylococcus aureus; Substrate Specificity; Temperature | 2010 |
Conformation dependence of the DαDα stretch mode in peptides: Side-chain influence in dipeptide structures.
Topics: Alanine; Dipeptides; Glycine; Isoleucine; Leucine; Models, Molecular; Molecular Conformation; Peptides; Phenylalanine; Protein Conformation; Serine; Valine; Water | 2010 |
Kinetic studies of Gly28:Ser mutant form of Bacillus pumilus lipase: changes in k(cat) and thermal dependence.
Topics: Algorithms; Amino Acid Sequence; Amino Acid Substitution; Bacillus; Bacterial Proteins; Biocatalysis; Cloning, Molecular; DNA, Bacterial; Enzyme Stability; Glycine; Kinetics; Lipase; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serine; Temperature | 2010 |
N-arachidonyl-glycine modulates synaptic transmission in superficial dorsal horn.
Topics: Animals; Arachidonic Acids; Glycine; Inhibitory Postsynaptic Potentials; Miniature Postsynaptic Potentials; N-Methylaspartate; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Sarcosine; Serine; Spinal Cord; Synaptic Transmission | 2010 |
Acquisition of Raman spectra of amino acids using portable instruments: outdoor measurements and comparison.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; beta-Alanine; Glutamic Acid; Glutamine; Glycine; Methionine; Proline; Research Design; Robotics; Serine; Spectrum Analysis, Raman; Transportation; Tryptophan; Tyrosine; Workplace | 2010 |
The biological conversion of l-serine to glycine.
Topics: Glycine; Humans; Serine | 1946 |
Metabolic basis for the self-referential genetic code.
Topics: Carbon; Evolution, Molecular; Genetic Code; Glycine; Glycine Dehydrogenase (Decarboxylating); Glycine Hydroxymethyltransferase; Glycolysis; Glyoxylates; Metabolome; Protein Biosynthesis; Ribonucleoproteins; RNA, Transfer; Serine | 2011 |
Mechanistic studies of peptide self-assembly: transient α-helices to stable β-sheets.
Topics: Amino Acid Substitution; Glycine; Humans; Islet Amyloid Polypeptide; Nuclear Magnetic Resonance, Biomolecular; Proline; Protein Structure, Secondary; Serine | 2010 |
The effect of the Gly139His, Gly143His, and Ser142His mouse heme oxygenase-1 mutants on the HO reaction in vivo and in vitro.
Topics: Amino Acid Substitution; Anemia; Animals; Animals, Newborn; Chlorocebus aethiops; COS Cells; Female; Glycine; Heme Oxygenase-1; Histidine; Iron Overload; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NIH 3T3 Cells; Serine; Splenomegaly | 2011 |
Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice.
Topics: Animals; Cell Survival; Glycine; Hippocampus; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice; Mice, Transgenic; Neurites; Neurogenesis; Physical Conditioning, Animal; Protein Serine-Threonine Kinases; Serine | 2011 |
Importance of position 170 in the inhibition of GES-type β-lactamases by clavulanic acid.
Topics: Anti-Bacterial Agents; Asparagine; beta-Lactamase Inhibitors; beta-Lactamases; Chromatography, Liquid; Clavulanic Acid; Enzyme Inhibitors; Glycine; Microbial Sensitivity Tests; Serine; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship | 2011 |
123I-MIBG cardiac uptake and smell identification in parkinsonian patients with LRRK2 mutations.
Topics: 3-Iodobenzylguanidine; Adult; Aged; Aged, 80 and over; Female; Glycine; Heart; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Parkinson Disease; Parkinsonian Disorders; Polymorphism, Single Nucleotide; Protein Serine-Threonine Kinases; Radionuclide Imaging; Radiopharmaceuticals; Serine; Severity of Illness Index; Smell; Statistics, Nonparametric | 2011 |
Structural and functional roles of small group-conserved amino acids present on helix-H7 in the β(2)-adrenergic receptor.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amino Acid Substitution; Amino Acids; Animals; Binding Sites; Chlorocebus aethiops; COS Cells; Cricetinae; Cyclic AMP; Dihydroalprenolol; Glycine; HEK293 Cells; Humans; Hydrogen Bonding; Isoproterenol; Models, Molecular; Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Radioligand Assay; Receptors, Adrenergic, beta-2; Serine; Structure-Activity Relationship | 2011 |
Effects of glycine-extended and serine13-phosphorylated forms of peptide YY on food intake in rats.
Topics: Animals; Feeding Behavior; Glycine; Peptide YY; Phosphorylation; Rats; Serine | 2011 |
Free energy simulation to investigate the effect of amino acid sequence environment on the severity of osteogenesis imperfecta by glycine mutations in collagen.
Topics: Amino Acid Sequence; Amino Acid Substitution; Collagen Type I; Entropy; Extracellular Matrix; Genes, Lethal; Glycine; Humans; Molecular Dynamics Simulation; Molecular Sequence Data; Mutation; Osteogenesis Imperfecta; Phenotype; Protein Conformation; Serine | 2011 |
Development of chemically defined media supporting high cell density growth of Ketogulonicigenium vulgare and Bacillus megaterium.
Topics: Bacillus megaterium; Biomass; Biotin; Culture Media; Glycine; Niacin; Proline; Rhodobacteraceae; Serine; Sorbose; Sugar Acids; Threonine; Zea mays | 2011 |
Substantia nigra hyperechogenicity with LRRK2 G2019S mutations.
Topics: Adult; Age Factors; Aged; Female; Genetic Predisposition to Disease; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine; Substantia Nigra; Ultrasonography, Doppler, Transcranial | 2011 |
Phenotypic heterogeneity in a large Thai slow-channel congenital myasthenic syndrome kinship.
Topics: Adult; Aged; Child; Child, Preschool; Family Health; Female; Glycine; Humans; Male; Middle Aged; Mutation; Myasthenic Syndromes, Congenital; Phenotype; Receptors, Nicotinic; Serine; Siblings; Thailand; Young Adult | 2011 |
The lrrk2 p.Gly2019Ser mutation is uncommon in a Danish cohort with various neurodegenerative disorders.
Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Denmark; Female; Genome-Wide Association Study; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Neurodegenerative Diseases; Protein Serine-Threonine Kinases; Serine | 2011 |
Transient kinetic analysis of L-serine interaction with Escherichia coli D-3-phosphoglycerate dehydrogenase containing amino acid mutations in the hinge regions.
Topics: Algorithms; Amino Acid Substitution; Amino Acids; Binding Sites; Biocatalysis; Escherichia coli Proteins; Glycine; Kinetics; Models, Molecular; Mutation; Phosphoglycerate Dehydrogenase; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors; Valine | 2011 |
Glycine inhibitory dysfunction turns touch into pain through astrocyte-derived D-serine.
Topics: Analysis of Variance; Animals; Astrocytes; CD11b Antigen; Citrates; Disease Models, Animal; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; Glycine; Hyperalgesia; Male; Oncogene Proteins v-fos; Pain Measurement; Rats; Rats, Sprague-Dawley; Serine; Spinal Nerve Roots; Strychnine; Time Factors | 2011 |
Oral administration of glycine increases extracellular serotonin but not dopamine in the prefrontal cortex of rats.
Topics: Administration, Oral; Animals; Dopamine; Extracellular Space; Glycine; Male; Microdialysis; Prefrontal Cortex; Rats; Rats, Wistar; Serine; Serotonin | 2011 |
Glutamate receptor-like genes form Ca2+ channels in pollen tubes and are regulated by pistil D-serine.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Arabidopsis; Calcium; Calcium Channels; Calcium Signaling; Cell Membrane; Cytosol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flowers; Gene Expression Regulation, Plant; Genes, Plant; Glycine; Morphogenesis; Nicotiana; Patch-Clamp Techniques; Plants, Genetically Modified; Pollen Tube; Racemases and Epimerases; Receptors, Glutamate; Serine | 2011 |
Differential regulation of photorespiratory gene expression by moderate and severe salt and drought stress in relation to oxidative stress.
Topics: Adaptation, Physiological; Catalase; Droughts; Gene Expression Regulation, Plant; Glycine; Glyoxylates; Hydrogen Peroxide; Liliaceae; Malondialdehyde; Oxidative Stress; Peroxidases; Photosynthesis; Plant Transpiration; Serine; Sodium Chloride; Stress, Physiological; Up-Regulation; Water | 2011 |
Stabilization of triple-helical structures of collagen peptides containing a Hyp-Thr-Gly, Hyp-Val-Gly, or Hyp-Ser-Gly sequence.
Topics: Amino Acid Sequence; Circular Dichroism; Collagen; Crystallization; Crystallography, X-Ray; Glycine; Hydroxyproline; Molecular Conformation; Molecular Sequence Data; Peptides; Proline; Protein Conformation; Protein Structure, Secondary; Sequence Homology, Amino Acid; Serine; Threonine; Valine | 2011 |
LRRK2 G2019S mutations may be increased in Puerto Ricans.
Topics: Adult; Aged; Female; Glycine; Hispanic or Latino; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Parkinson Disease; Protein Serine-Threonine Kinases; Regression Analysis; Serine; United States | 2011 |
The G82S polymorphism promotes glycosylation of the receptor for advanced glycation end products (RAGE) at asparagine 81: comparison of wild-type rage with the G82S polymorphic variant.
Topics: Asparagine; Cell Line; Cell Membrane; Gene Expression Regulation; Glycine; Glycosylation; Humans; Inflammation; Ligands; Mutation; Polymorphism, Genetic; Protein Binding; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serine; Transfection | 2011 |
Mood and cognition in leucine-rich repeat kinase 2 G2019S Parkinson's disease.
Topics: Aged; Aged, 80 and over; Cognition Disorders; Female; Genetic Predisposition to Disease; Glycine; Humans; Jews; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mood Disorders; Neuropsychological Tests; Parkinson Disease; Protein Serine-Threonine Kinases; Psychiatric Status Rating Scales; Serine | 2011 |
Pharmacokinetics and cerebral distribution of glycine administered to rats.
Topics: Administration, Oral; Animals; Autoradiography; Biological Availability; Biological Transport; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Diffusion; Dose-Response Relationship, Drug; Glycine; Male; Radiography; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine | 2012 |
Kin-cohort analysis of LRRK2-G2019S penetrance in Parkinson's disease.
Topics: Aged; Aged, 80 and over; Cohort Studies; DNA Mutational Analysis; Family Health; Female; Glycine; Humans; Kaplan-Meier Estimate; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Odds Ratio; Parkinson Disease; Penetrance; Protein Serine-Threonine Kinases; Serine | 2011 |
Association study of DRD3 gene in schizophrenia in Mexican sib-pairs.
Topics: Adult; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Male; Mexico; Polymorphism, Single Nucleotide; Receptors, Dopamine D3; Schizophrenia; Serine; Siblings; Young Adult | 2011 |
Confirmation of the severe phenotypic effect of serine at codon 41 of the superoxide dismutase 1 gene.
Topics: Adult; Amyotrophic Lateral Sclerosis; Family Health; Female; Glycine; Humans; Male; Middle Aged; Models, Molecular; Phenotype; Serine; Superoxide Dismutase; Superoxide Dismutase-1 | 2011 |
Luteinising hormone β-subunit gene Gly102Ser variant and oxidative stress biomarkers in Egyptian infertile males.
Topics: Base Sequence; Biomarkers; DNA Primers; Egypt; Glycine; Humans; Infertility, Male; Luteinizing Hormone, beta Subunit; Male; Oxidative Stress; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Serine | 2012 |
An abiotic analogue of the nuclear pore complex hydrogel.
Topics: Acrylamide; Acrylic Resins; Active Transport, Cell Nucleus; Glycine; Hydrogels; Hydrophobic and Hydrophilic Interactions; Karyopherins; Microscopy, Fluorescence; Molecular Mimicry; Nuclear Pore; Nuclear Pore Complex Proteins; Oligopeptides; Phenylalanine; Polymerization; Serine | 2011 |
PGC1α gene Gly482Ser polymorphism predicts improved metabolic, inflammatory and vascular outcomes following bariatric surgery.
Topics: Adolescent; Adult; Brazil; C-Reactive Protein; Carotid Intima-Media Thickness; Comorbidity; Coronary Artery Disease; Female; Gastric Bypass; Glycine; Humans; Interleukin-6; Male; Middle Aged; Obesity, Morbid; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Serine; Treatment Outcome; Weight Loss; Young Adult | 2012 |
Investigation of biomolecules trapped in fluid inclusions inside halite crystals by Raman spectroscopy.
Topics: Alanine; Amino Acids; beta-Alanine; Crystallization; Exobiology; Extraterrestrial Environment; gamma-Aminobutyric Acid; Glycine; Serine; Spectrum Analysis, Raman | 2011 |
Increased concentrations of both NMDA receptor co-agonists D-serine and glycine in global ischemia: a potential novel treatment target for perinatal asphyxia.
Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Cell Line, Tumor; Glycine; Humans; Hypoxia; Hypoxia-Ischemia, Brain; Infant, Newborn; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Reperfusion; Respiratory Distress Syndrome, Newborn; Serine; Swine | 2012 |
Is there any association between GLY82 ser polymorphism of rage gene and Turkish diabetic and non diabetic patients with coronary artery disease?
Topics: Coronary Artery Disease; Demography; Diabetes Complications; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Glycine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Factors; Serine; Turkey | 2012 |
Electrophysiological analysis of the modulation of NMDA-receptors function by D-serine and glycine in the central nervous system.
Topics: Animals; Central Nervous System; Glycine; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine | 2012 |
String kernels and high-quality data set for improved prediction of kinked helices in α-helical membrane proteins.
Topics: Animals; Computational Biology; Databases, Protein; Glycine; Humans; Membrane Proteins; Models, Molecular; Models, Statistical; Proline; Protein Structure, Secondary; Research Design; Serine; Support Vector Machine | 2011 |
The NMDA receptor co-agonists, D-serine and glycine, regulate neuronal dendritic architecture in the somatosensory cortex.
Topics: Animals; Brain-Derived Neurotrophic Factor; Dendrites; Gene Expression Profiling; Glycine; Immunohistochemistry; Mice; Mice, Knockout; Neurons; Oligonucleotide Array Sequence Analysis; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; Schizophrenia; Serine; Somatosensory Cortex | 2012 |
Serine biosynthesis with one carbon catabolism and the glycine cleavage system represents a novel pathway for ATP generation.
Topics: Adenosine Triphosphate; Animals; Carbon; Cell Proliferation; Glycine; Glycolysis; Kinetics; Liver Neoplasms, Experimental; Mice; Serine; Transcription, Genetic; Up-Regulation | 2011 |
A large family with Carney complex caused by the S147G PRKAR1A mutation shows a unique spectrum of disease including adrenocortical cancer.
Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenal Gland Diseases; Adrenocortical Carcinoma; Adult; Amino Acid Substitution; Carney Complex; Child; Child, Preschool; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Family; Female; Glycine; Humans; Male; Middle Aged; Mutation, Missense; Serine; Young Adult | 2012 |
Methionine and serine synergistically suppress hyperhomocysteinemia induced by choline deficiency, but not by guanidinoacetic acid, in rats fed a low casein diet.
Topics: Animals; Caseins; Choline; Diet; Dietary Supplements; Drug Synergism; Glycine; Hyperhomocysteinemia; Male; Methionine; Rats; Rats, Wistar; Serine | 2011 |
Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis.
Topics: Amino Acid Sequence; Antigens, CD; Carcinoma, Non-Small-Cell Lung; Cell Adhesion Molecules, Neuronal; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA-Binding Proteins; Fetal Proteins; Glycine; Glycine Dehydrogenase (Decarboxylating); Humans; Lung Neoplasms; Molecular Sequence Data; Neoplasms; RNA-Binding Proteins; Sequence Alignment; Serine; Thermus thermophilus; Transplantation, Heterologous | 2012 |
[Determination of amino acid contents in cottonseeds using near infrared reflectance spectroscopy].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Calibration; Cottonseed Oil; Cystine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Spectroscopy, Near-Infrared; Threonine; Tyrosine; Valine | 2011 |
Construction and functional characterization of double and triple mutants of parallel beta-bulge of ubiquitin.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cloning, Molecular; Conserved Sequence; Escherichia coli; Evolution, Molecular; Glutamine; Glycine; Heat-Shock Response; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plasmids; Polymerase Chain Reaction; Protein Stability; Protein Structure, Secondary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Ubiquitin | 2011 |
Metabolism of amino acids during hyposmotic adaptation in the whiteleg shrimp, Litopenaeus vannamei.
Topics: Adaptation, Physiological; Ammonia; Animals; Chromatography, High Pressure Liquid; Glycine; Hemolymph; L-Serine Dehydratase; Male; Muscles; Osmolar Concentration; Oxygen Consumption; Penaeidae; Salinity; Serine; Water-Electrolyte Balance | 2012 |
Photosynthesis, photorespiration and productivity of wheat and soybean genotypes.
Topics: Biological Evolution; Carbon Dioxide; Cell Respiration; Crops, Agricultural; Enzyme Activation; Genotype; Glyceric Acids; Glycine; Glycine max; Glycolates; Photosynthesis; Plant Leaves; Ribulose-Bisphosphate Carboxylase; Seeds; Serine; Species Specificity; Triticum | 2012 |
Timing-dependent reduction in ethanol sedation and drinking preference by NMDA receptor co-agonist d-serine.
Topics: Alcohol Drinking; Alcoholic Intoxication; Analysis of Variance; Animals; Ethanol; Glutamic Acid; Glycine; Male; Mice; Motor Activity; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Serine; Time Factors | 2012 |
Metal cation dependence of interactions with amino acids: bond energies of Cs+ to Gly, Pro, Ser, Thr, and Cys.
Topics: Cations; Cesium; Cysteine; Glycine; Proline; Quantum Theory; Serine; Threonine | 2012 |
Short- and long-term dynamic responses of the metabolic network and gene expression in yeast to a transient change in the nutrient environment.
Topics: Carbon; Catabolite Repression; Energy Metabolism; Folic Acid; Gene Expression Profiling; Gene Expression Regulation, Fungal; Glucose; Glycine; Inosine; Metabolic Networks and Pathways; Nitrogen; Nucleotides; Quaternary Ammonium Compounds; Saccharomyces cerevisiae; Serine; Systems Biology; Transcriptome | 2012 |
Different serine and glycine metabolism in patients with schizophrenia receiving clozapine.
Topics: Adult; Aged; Antipsychotic Agents; Clozapine; Excitatory Amino Acids; Female; Glycine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Serine; Statistics, Nonparametric; Young Adult | 2012 |
Structural insights into the metabolism of 2-chlorodibenzofuran by an evolved biphenyl dioxygenase.
Topics: Benzofurans; Burkholderia; Catalysis; Crystallization; Dioxygenases; Glycine; Mutation; Protein Conformation; Serine | 2012 |
Metabolic engineering and flux analysis of Corynebacterium glutamicum for L-serine production.
Topics: Bacterial Proteins; Bioreactors; Corynebacterium glutamicum; Fermentation; Gene Expression Regulation, Bacterial; Glucose; Glycine; Glycine Hydroxymethyltransferase; Glycolysis; Metabolic Engineering; Pentose Phosphate Pathway; Phosphoglycerate Dehydrogenase; Phosphoglycerate Kinase; Pyruvic Acid; Serine | 2012 |
TCN 201 selectively blocks GluN2A-containing NMDARs in a GluN1 co-agonist dependent but non-competitive manner.
Topics: Algorithms; Animals; Cerebral Cortex; Electrophysiological Phenomena; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Neurons; Oocytes; Patch-Clamp Techniques; Plasmids; Rats; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; RNA, Complementary; Serine; Sulfonamides; Transfection; Xenopus laevis | 2012 |
Overexpression of serine hydroxymethyltransferase from halotolerant cyanobacterium in Escherichia coli results in increased accumulation of choline precursors and enhanced salinity tolerance.
Topics: Amino Acid Sequence; Betaine; Choline; Cloning, Molecular; Cyanobacteria; Enzyme Activation; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Bacterial; Glycine; Glycine Hydroxymethyltransferase; Molecular Sequence Data; Recombinant Proteins; RNA, Bacterial; Salinity; Salt Tolerance; Serine; Sodium Chloride | 2012 |
Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like protein.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Dynamins; Embryo, Mammalian; Glycine; Green Fluorescent Proteins; GTP Phosphohydrolases; Humans; Immunoprecipitation; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice; Microscopy, Confocal; Microtubule-Associated Proteins; Mitochondria; Mitochondrial Proteins; Mutation; Neurons; Protein Serine-Threonine Kinases; Reactive Oxygen Species; RNA, Small Interfering; Serine; Transfection | 2012 |
Dyskinesias in patients with Parkinson's disease: effect of the leucine-rich repeat kinase 2 (LRRK2) G2019S mutation.
Topics: Adult; Aged; Aged, 80 and over; DNA Mutational Analysis; Dyskinesia, Drug-Induced; Female; Gene Frequency; Genetic Predisposition to Disease; Glycine; Humans; Israel; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Levodopa; Longitudinal Studies; Male; Middle Aged; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Retrospective Studies; Serine; Statistics, Nonparametric; Young Adult | 2012 |
CD226 Gly307Ser association with neuromyelitis optica in Southern Han Chinese.
Topics: Adult; Age of Onset; Antigens, Differentiation, T-Lymphocyte; Asian People; Case-Control Studies; China; Confidence Intervals; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Male; Neuromyelitis Optica; Odds Ratio; Serine; Young Adult | 2012 |
Target site mutation and reduced translocation are present in a glyphosate-resistant Lolium multiflorum Lam. biotype from Spain.
Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Adaptation, Physiological; Amino Acid Sequence; Base Sequence; Biological Transport; Glycine; Glyphosate; Herbicides; Lolium; Molecular Sequence Data; Mutation; Plant Leaves; Proline; Serine; Shikimic Acid; Spain; Species Specificity; Stress, Physiological | 2012 |
Factors contributing to the resistivity of a higher casein diet against choline deficiency-induced hyperhomocysteinemia in rats.
Topics: Animals; Caseins; Choline; Choline Deficiency; Diet; Glycine; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rats; Rats, Wistar; Serine | 2012 |
Selective lighting up of segments around Gly, Ala and Ser/Thr in proteins.
Topics: Alanine; Glycine; Humans; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Serine; Threonine; Ubiquitin | 2012 |
Synaptic and extrasynaptic NMDA receptors are gated by different endogenous coagonists.
Topics: Animals; Cell Membrane; Cells, Cultured; Glycine; Hippocampus; Long-Term Potentiation; Long-Term Synaptic Depression; Neuroglia; Neuronal Plasticity; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine; Synapses | 2012 |
Predictive modeling of biomass component tradeoffs in Brassica napus developing oilseeds based on in silico manipulation of storage metabolism.
Topics: Biomass; Brassica napus; Carbon; Citric Acid Cycle; Computational Biology; Computer Simulation; Glycine; Metabolic Networks and Pathways; Models, Biological; Plant Oils; Plant Proteins; Seeds; Serine; Triglycerides | 2012 |
A dimerization defect caused by a glycine substitution at position 420 by serine in tissue-nonspecific alkaline phosphatase associated with perinatal hypophosphatasia.
Topics: Alkaline Phosphatase; Animals; Blotting, Western; Centrifugation, Density Gradient; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Dimerization; Glycine; Humans; Hypophosphatasia; Mutation; Serine | 2012 |
Serine is a natural ligand and allosteric activator of pyruvate kinase M2.
Topics: Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Enzyme Activators; Glucose; Glycine; Humans; Ligands; Pyruvate Kinase; Pyruvic Acid; Recombinant Proteins; Serine | 2012 |
[The absence of the common LRRK2 G2019S mutation in 120 young onset Hungarian Parkinon's disease patients].
Topics: Adult; Age of Onset; Aged; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Glycine; Humans; Hungary; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Parkinson Disease; Point Mutation; Protein Serine-Threonine Kinases; Serine | 2012 |
The tRNA recognition mechanism of folate/FAD-dependent tRNA methyltransferase (TrmFO).
Topics: Anticodon; Bacterial Proteins; Base Sequence; Electrophoretic Mobility Shift Assay; Enzyme Assays; Flavin-Adenine Dinucleotide; Folic Acid; Gene Expression Regulation, Bacterial; Glycine; Glycine Hydroxymethyltransferase; Kinetics; Models, Biological; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; RNA, Messenger; RNA, Transfer; RNA, Transfer, Phe; Serine; Substrate Specificity; Thermus thermophilus; tRNA Methyltransferases; Uridine | 2012 |
Overexpression of the mitochondrial folate and glycine-serine pathway: a new determinant of methotrexate selectivity in tumors.
Topics: Biological Transport; Folic Acid; Folic Acid Antagonists; Glycine; Humans; Methotrexate; Mitochondria; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Serine; Transcriptome | 2013 |
One-pot synthesis of α-amino acids from CO2 using a bismetal reagent with Si-B bond.
Topics: Amino Acids; Carbon Dioxide; Glycine; Imines; Indicators and Reagents; Leucine; Molecular Structure; Serine; Stereoisomerism | 2012 |
North-south gradients in plasma concentrations of B-vitamins and other components of one-carbon metabolism in Western Europe: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study.
Topics: Adult; Aged; Alcohol Drinking; Chronic Disease; Ethnicity; Europe; Female; Folic Acid; Glycine; Health Behavior; Humans; Life Style; Male; Middle Aged; Prospective Studies; Sarcosine; Serine; Sex Factors; Smoking; Vitamin B 12 | 2013 |
The purine-utilizing bacterium Clostridium acidurici 9a: a genome-guided metabolic reconsideration.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Base Sequence; Chromosomes, Bacterial; Clostridium; Drug Resistance, Microbial; Fermentation; Genome, Bacterial; Glycine; Glycine Hydroxymethyltransferase; Multienzyme Complexes; Plasmids; Purines; Sequence Analysis, DNA; Serine | 2012 |
Discrimination based on Gly and Arg/Ser at position 673 between dipeptidyl-peptidase (DPP) 7 and DPP11, widely distributed DPPs in pathogenic and environmental gram-negative bacteria.
Topics: Amino Acid Sequence; Arginine; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Environment; Gene Expression Regulation, Bacterial; Glycine; Gram-Negative Bacteria; Molecular Sequence Data; Phylogeny; Serine; Substrate Specificity | 2013 |
Cerebral pathological and compensatory mechanisms in the premotor phase of leucine-rich repeat kinase 2 parkinsonism.
Topics: Adult; Analysis of Variance; Biomechanical Phenomena; Brain; Cerebral Cortex; DNA Mutational Analysis; Family Health; Female; Functional Laterality; Glycine; Humans; Image Processing, Computer-Assisted; Imagination; Judaism; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Magnetic Resonance Imaging; Male; Middle Aged; Motor Activity; Mutation; Neural Pathways; Oxygen; Parkinsonian Disorders; Prospective Studies; Protein Serine-Threonine Kinases; Reaction Time; Rotation; Serine | 2012 |
Some Tetrahydropyranyl Derivatives of Glycine, Serine and Urea.
Topics: Glycine; Hydrogen-Ion Concentration; Hydrolysis; Pyrans; Serine; Urea; Water | 1961 |
Action of nicotine and analogs on acetylcholine receptors having mutations of transmitter-binding site residue αG153.
Topics: Anabasine; Dose-Response Relationship, Drug; Glycine; HEK293 Cells; Humans; Ion Channel Gating; Kidney; Lysine; Mutation; Nicotine; Patch-Clamp Techniques; Receptors, Cholinergic; Serine | 2013 |
Olfaction and imaging biomarkers in premotor LRRK2 G2019S-associated Parkinson disease.
Topics: Aged; Aged, 80 and over; Biomarkers; Chi-Square Distribution; Cohort Studies; Cross-Sectional Studies; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Nortropanes; Olfaction Disorders; Parkinson Disease; Protein Serine-Threonine Kinases; Serine; Severity of Illness Index; Smell; Substantia Nigra; Tomography, Emission-Computed, Single-Photon; Ultrasonography, Doppler, Transcranial | 2013 |
No correlation between plasma NMDA-related glutamatergic amino acid levels and cognitive function in medicated patients with schizophrenia.
Topics: Adolescent; Adult; Aged; Alanine; Antipsychotic Agents; Basal Ganglia Diseases; Biomarkers; Brief Psychiatric Rating Scale; Cholinergic Antagonists; Cognition Disorders; Drug Therapy, Combination; Female; Glycine; Humans; Male; Middle Aged; Neuropsychological Tests; Reference Values; Schizophrenia; Serine; Young Adult | 2012 |
Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes.
Topics: Adult; Betaine; Diabetes Mellitus, Type 2; Female; Glycine; Humans; Insulin Resistance; Male; Middle Aged; Serine | 2013 |
Neuronal D-serine and glycine release via the Asc-1 transporter regulates NMDA receptor-dependent synaptic activity.
Topics: Amino Acid Transport System y+; Animals; Animals, Newborn; Cells, Cultured; Glycine; HEK293 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Synaptic Transmission | 2013 |
A fluorescent peptide substrate facilitates investigation of ghrelin recognition and acylation by ghrelin O-acyltransferase.
Topics: Acylation; Acyltransferases; Amino Acid Sequence; Enzyme Assays; Enzyme Inhibitors; Fluorescent Dyes; Ghrelin; Glycine; Humans; Molecular Sequence Data; Peptidomimetics; Protein Binding; Serine; Structure-Activity Relationship; Substrate Specificity | 2013 |
Serine acts as a metabolic signal for the transcriptional control of photorespiration-related genes in Arabidopsis.
Topics: Arabidopsis; Arabidopsis Proteins; Cell Respiration; Circadian Rhythm; Gene Expression Regulation, Plant; Glycine; Light; Metabolomics; Peroxisomes; Photosynthesis; Plant Leaves; Plants, Genetically Modified; RNA, Messenger; RNA, Plant; Seedlings; Sequence Deletion; Serine | 2013 |
Astrocytes release D-serine by a large vesicle.
Topics: Adenosine Diphosphate; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Biophysics; Calcium; Cytoplasmic Vesicles; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Exocytosis; Female; Glycine; Hippocampus; In Vitro Techniques; Male; Microscopy, Electron, Transmission; Patch-Clamp Techniques; Purinergic P2Y Receptor Antagonists; Rats; Rats, Sprague-Dawley; Serine; Valine | 2013 |
[Importance of the location of NMDA glutamate receptors].
Topics: Animals; Glycine; Humans; Long-Term Potentiation; Receptors, N-Methyl-D-Aspartate; Serine; Synapses | 2013 |
Identity of endogenous NMDAR glycine site agonist in amygdala is determined by synaptic activity level.
Topics: Amygdala; Animals; Astrocytes; D-Amino-Acid Oxidase; Excitatory Postsynaptic Potentials; Female; Gliotoxin; Glycine; In Vitro Techniques; Long-Term Potentiation; Male; Mice; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synapses | 2013 |
D-amino acid aberrations in cerebrospinal fluid and plasma of smokers.
Topics: Adult; Alanine; Alcohol Drinking; Excitatory Amino Acid Agonists; Female; Glycine; Humans; Male; Proline; Self Report; Serine; Smoking; Stereoisomerism | 2013 |
Structural, kinetic, and pharmacodynamic mechanisms of D-amino acid oxidase inhibition by small molecules.
Topics: Animals; Behavior, Animal; Binding, Competitive; Catalytic Domain; D-Amino-Acid Oxidase; Enzyme Inhibitors; Glycine; Humans; Kinetics; Male; Molecular Docking Simulation; Neuroglia; Rats; Rats, Sprague-Dawley; Serine; Small Molecule Libraries | 2013 |
Electron densities by the maximum entropy method (MEM) for various types of prior densities: a case study on three amino acids and a tripeptide.
Topics: Alanine; Entropy; Glycine; Hydrogen Bonding; Models, Molecular; Oligopeptides; Serine; X-Ray Diffraction | 2013 |
Dietary glycine+serine responses of male broilers given low-protein diets with different concentrations of threonine.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Creatine; Diet; Diet, Protein-Restricted; Dietary Proteins; Dietary Supplements; Digestion; Dose-Response Relationship, Drug; Glycine; Male; Pectoralis Muscles; Serine; Threonine; Uric Acid | 2013 |
Divergent α-synuclein solubility and aggregation properties in G2019S LRRK2 Parkinson's disease brains with Lewy Body pathology compared to idiopathic cases.
Topics: Aged; Aged, 80 and over; alpha-Synuclein; Brain; Female; Gene Expression Regulation; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Lewy Bodies; Male; Parkinson Disease; Postmortem Changes; Protein Serine-Threonine Kinases; Serine | 2013 |
Sarcosine and other metabolites along the choline oxidation pathway in relation to prostate cancer--a large nested case-control study within the JANUS cohort in Norway.
Topics: Betaine; Biomarkers, Tumor; Case-Control Studies; Choline; Chromatography, Liquid; Cohort Studies; Glycine; Humans; Male; Mass Spectrometry; Middle Aged; Norway; Oxidation-Reduction; Prostatic Neoplasms; Sarcosine; Serine | 2014 |
Glycine transporter 1 modulates GABA release from amacrine cells by controlling occupancy of coagonist binding site of NMDA receptors.
Topics: Amacrine Cells; Animals; Axons; Binding Sites; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fish Proteins; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Glycine Agents; Glycine Plasma Membrane Transport Proteins; Goldfish; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Serine; Strychnine | 2013 |
Rescue of NMDAR-dependent synaptic plasticity in Fmr1 knock-out mice.
Topics: Animals; Fragile X Mental Retardation Protein; Fragile X Syndrome; Glycine; Hippocampus; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Receptors, N-Methyl-D-Aspartate; Serine | 2015 |
Monitoring neurochemical release from astrocytes using in vitro microdialysis coupled with high-speed capillary electrophoresis.
Topics: Amino Acids; Animals; Astrocytes; Cell Survival; Cells, Cultured; Electrophoresis, Capillary; Glycine; Mice; Microdialysis; Neurotransmitter Agents; Serine; Taurine | 2013 |
H2A.Z acidic patch couples chromatin dynamics to regulation of gene expression programs during ESC differentiation.
Topics: Animals; Asparagine; Cell Differentiation; Cell Lineage; Chromatin; Embryonic Development; Embryonic Stem Cells; Gene Expression Regulation, Developmental; Glycine; Histones; Mice; Nucleosomes; Promoter Regions, Genetic; Serine | 2013 |
ATP binding to human serine racemase is cooperative and modulated by glycine.
Topics: Adenosine Triphosphate; Allosteric Site; Catalytic Domain; Enzyme Stability; Glycine; Humans; Kinetics; Ligands; Models, Biological; Models, Molecular; Protein Conformation; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Serine; Spectrometry, Fluorescence; Stereoisomerism | 2013 |
ALX 1393 inhibits spontaneous network activity by inducing glycinergic tonic currents in the spinal ventral horn.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Anterior Horn Cells; Biophysical Phenomena; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glycine; Glycine Agents; Glycine Plasma Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Nerve Net; Organ Culture Techniques; Patch-Clamp Techniques; Serine; Spinal Cord; Time Factors; Valine | 2013 |
LRRK2 G2385R variant carriers of female Parkinson's disease are more susceptible to motor fluctuation.
Topics: Aged; Female; Genotype; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mental Status Schedule; Middle Aged; Parkinson Disease; Protein Serine-Threonine Kinases; Serine; Severity of Illness Index; Sex Factors; Statistics, Nonparametric | 2013 |
O-xylosylation in a recombinant protein is directed at a common motif on glycine-serine linkers.
Topics: Amino Acid Sequence; Animals; Carbohydrate Sequence; CHO Cells; Cricetinae; Cricetulus; Glycine; Glycosylation; Humans; Molecular Sequence Data; Protein Engineering; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Fusion Proteins; Serine; Tenascin; Xylose | 2013 |
Rothmund-Thomson syndrome and glomerulonephritis in a homozygous C1q-deficient patient due to a Gly164Ser C1qC mutation.
Topics: Adult; Cataract; Cohort Studies; Complement C1q; Erythema; Exons; Glomerulonephritis; Glycine; Homozygote; Humans; Introns; Male; Mutation; Phenotype; Rothmund-Thomson Syndrome; Serine; Skin Diseases; Spain | 2014 |
Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells.
Topics: Adenosine Triphosphate; Amino Acid Oxidoreductases; Animals; Carrier Proteins; Cell Line, Tumor; Embryonic Stem Cells; Energy Metabolism; Fatty Acids; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Glycine; Humans; Male; Metabolic Flux Analysis; Metabolic Networks and Pathways; Methotrexate; Mice; Multienzyme Complexes; NADP; Neoplasms; Protein Biosynthesis; Purines; Serine; Transferases | 2013 |
Parkinson disease phenotype in Ashkenazi Jews with and without LRRK2 G2019S mutations.
Topics: Aged; Female; Genotype; Glycine; Humans; Jews; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Phenotype; Protein Serine-Threonine Kinases; Regression Analysis; Serine; Severity of Illness Index; Surveys and Questionnaires | 2013 |
In vitro Characterization of a small molecule inhibitor of the alanine serine cysteine transporter -1 (SLC7A10).
Topics: Amino Acid Transport System y+; Amino Acids; Animals; Cell Line; Cerebral Cortex; Excitatory Amino Acid Agonists; Glycine; Histidine; Humans; Indoles; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Small Molecule Libraries; Synaptosomes | 2014 |
The G2019S LRRK2 mutation: another morbid burden for Ashkenazi Jews may provide new insights on sporadic Parkinson's disease.
Topics: Female; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine | 2013 |
The histone H3 methyltransferase G9A epigenetically activates the serine-glycine synthesis pathway to sustain cancer cell survival and proliferation.
Topics: Animals; Autophagy; Azepines; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Epigenomics; Glycine; HeLa Cells; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Mice; Microtubule-Associated Proteins; Quinazolines; Ribosomes; Serine; Transcription, Genetic | 2013 |
Children with severe asthma have unique oxidative stress-associated metabolomic profiles.
Topics: Adolescent; Adrenal Cortex Hormones; Asthma; Child; Chromatography, High Pressure Liquid; Computational Biology; Drug Resistance; Ethanolamines; Female; Glycine; Humans; Lipid Peroxidation; Male; Metabolome; Oxidative Stress; Serine; Sphingosine N-Acyltransferase; Threonine | 2014 |
Expression levels of serine/glycine metabolism-related proteins in triple negative breast cancer tissues.
Topics: Adult; Aged; Female; Glycine; Glycine Hydroxymethyltransferase; Humans; Middle Aged; Phosphoglycerate Dehydrogenase; Proportional Hazards Models; Serine; Triple Negative Breast Neoplasms | 2014 |
NMDA receptor activation antagonizes the NMDA antagonist-induced antianxiety effect in the elevated plus-maze test in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Binding Sites; Brain; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Ligands; Male; Maze Learning; Mice; N-Methylaspartate; Quinolones; Receptors, N-Methyl-D-Aspartate; Serine | 2013 |
Molecular characterization of an alanine-, proline-, glycine-, threonine-, and serine-rich protein of the hard tick Haemaphysalis qinghaiensis and its effect as a vaccine against tick infestation in sheep.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; DNA, Complementary; Glycine; Immunity, Active; Ixodidae; Molecular Sequence Data; Phylogeny; Proline; Rabbits; Recombinant Proteins; Sequence Analysis, DNA; Serine; Sheep; Sheep Diseases; Threonine; Tick Infestations; Vaccination; Vaccines | 2014 |
A voxel-based morphometry and diffusion tensor imaging analysis of asymptomatic Parkinson's disease-related G2019S LRRK2 mutation carriers.
Topics: Adult; Brain; Cognition Disorders; Diffusion Tensor Imaging; Female; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Parkinson Disease; Protein Serine-Threonine Kinases; Serine; Severity of Illness Index | 2014 |
Stabilization studies on bacterially produced human paraoxonase 1 for improving its shelf life.
Topics: Animals; Aryldialkylphosphatase; Enzyme Stability; Escherichia coli; Freeze Drying; Glycine; Humans; Maltose; Serine; Serum Albumin, Bovine; Temperature; Trehalose | 2014 |
Metabolomics of asthma.
Topics: Asthma; Carnitine; Ethanolamines; Female; Glycine; Humans; Male; Methylamines; Oxidative Stress; Serine; Sphingosine N-Acyltransferase; Threonine | 2014 |
Reply: To PMID 24369803.
Topics: Asthma; Carnitine; Ethanolamines; Female; Glycine; Humans; Male; Methylamines; Oxidative Stress; Serine; Sphingosine N-Acyltransferase; Threonine | 2014 |
Reply: To PMID 24369802.
Topics: Asthma; Ethanolamines; Female; Glycine; Humans; Male; Oxidative Stress; Serine; Sphingosine N-Acyltransferase; Threonine | 2014 |
Gly25-Ser26 amyloid β-protein structural isomorphs produce distinct Aβ42 conformational dynamics and assembly characteristics.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Biophysical Phenomena; Click Chemistry; Glycine; Humans; Molecular Dynamics Simulation; Peptide Fragments; Protein Conformation; Protein Folding; Protein Isoforms; Protein Multimerization; Serine | 2014 |
Astroglial d-serine is the endogenous co-agonist at the presynaptic NMDA receptor in rat entorhinal cortex.
Topics: Animals; Astrocytes; Entorhinal Cortex; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine | 2014 |
Quantitative flux analysis reveals folate-dependent NADPH production.
Topics: Animals; Carbon; Cell Line; Cell Line, Tumor; Cytosol; Folic Acid; Glutathione; Glycine; HEK293 Cells; Humans; Isoenzymes; Leucovorin; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mitochondria; NADP; Oxidation-Reduction; Oxidative Stress; Pentose Phosphate Pathway; Serine; Tetrahydrofolates | 2014 |
Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells.
Topics: Carbon; Cell Growth Processes; Glycine; HCT116 Cells; Humans; MCF-7 Cells; Metabolic Networks and Pathways; Neoplasms; Serine | 2014 |
(G2019S) LRRK2 causes early-phase dysfunction of SNpc dopaminergic neurons and impairment of corticostriatal long-term depression in the PD transgenic mouse.
Topics: Animals; Apomorphine; Cerebral Cortex; Corpus Striatum; Dopamine Agonists; Dopaminergic Neurons; GABA Antagonists; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Long-Term Potentiation; Mice; Mice, Transgenic; Motor Activity; Mutation; Parkinson Disease; Picrotoxin; Protein Serine-Threonine Kinases; Radionuclide Imaging; Serine; Substantia Nigra; Tyrosine 3-Monooxygenase | 2014 |
Purification and characterization of carbon-phosphorus bond-cleavage enzyme from glyphosate degrading Pseudomonas putida T5.
Topics: Catalytic Domain; Chromatography, Gel; Enzyme Inhibitors; Enzyme Stability; Glycine; Glyphosate; Hydrogen-Ion Concentration; Kinetics; Lyases; Metals; Phenylmethylsulfonyl Fluoride; Pseudomonas putida; Serine; Substrate Specificity; Temperature | 2015 |
Glycine is a nutritionally essential amino acid for maximal growth of milk-fed young pigs.
Topics: Adenosine Triphosphatases; Amino Acid Transport Systems; Ammonia; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Body Composition; Body Weight; Dietary Supplements; Glutamine; Glutathione; Glycine; Glycine Plasma Membrane Transport Proteins; Jejunum; Milk; Protein Transport; Random Allocation; RNA, Messenger; Serine; Swine; Urea; Weight Gain | 2014 |
Tracing compartmentalized NADPH metabolism in the cytosol and mitochondria of mammalian cells.
Topics: Cell Line, Tumor; Cytosol; Glucose; Glycine; Humans; Isocitrate Dehydrogenase; Metabolic Flux Analysis; Mitochondria; NADP; Serine | 2014 |
Biochemical and cell biological properties of the human prohormone convertase 1/3 Ser357Gly mutation: a PC1/3 hypermorph.
Topics: Amino Acid Sequence; Enzyme Stability; Glycine; Humans; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutation, Missense; Proprotein Convertase 1; Protein Structure, Tertiary; Serine | 2014 |
D-serine prevents cognitive deficits induced by acute stress.
Topics: Acute Disease; Animals; Cognition Disorders; Corticosterone; Disease Models, Animal; Glycine; Hippocampus; Male; Memory; Mice, Inbred C57BL; Nootropic Agents; Prefrontal Cortex; Prepulse Inhibition; Reflex, Startle; Restraint, Physical; Serine; Stress, Psychological | 2014 |
Differential expression of enzymes associated with serine/glycine metabolism in different breast cancer subtypes.
Topics: Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Disease-Free Survival; Female; Glycine; Glycolysis; Humans; Middle Aged; Multivariate Analysis; Neoplasm Proteins; Phenotype; Serine | 2014 |
Expression of serine and glycine-related enzymes in phyllodes tumor.
Topics: Adult; Breast Neoplasms; Female; Glycine; Humans; Middle Aged; Phyllodes Tumor; Serine | 2014 |
LRRK2-G2019S mutation is not associated with an increased cancer risk: a kin-cohort study.
Topics: Case-Control Studies; Cohort Studies; Female; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mutation; Neoplasms; Protein Serine-Threonine Kinases; Risk Factors; Serine; Siblings | 2014 |
Genetic and pharmacological evidence that G2019S LRRK2 confers a hyperkinetic phenotype, resistant to motor decline associated with aging.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aging; Analysis of Variance; Animals; Brain; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycine; Humans; Hyperkinesis; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; NIH 3T3 Cells; Protein Serine-Threonine Kinases; Serine; Time Factors | 2014 |
Investigation of a substrate-specifying residue within Papaver somniferum and Catharanthus roseus aromatic amino acid decarboxylases.
Topics: Amino Acid Sequence; Aromatic-L-Amino-Acid Decarboxylases; Catalytic Domain; Catharanthus; Glycine; Molecular Docking Simulation; Molecular Sequence Data; Mutagenesis; Papaver; Recombinant Proteins; Sequence Alignment; Serine; Substrate Specificity; Tyrosine Decarboxylase | 2014 |
Changes in plasma D-serine, L-serine, and glycine levels in treatment-resistant schizophrenia before and after clozapine treatment.
Topics: Adult; Antipsychotic Agents; Case-Control Studies; Clozapine; Female; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Schizophrenia; Serine; Stereoisomerism; Treatment Failure | 2014 |
Effects of a glycine transporter-1 inhibitor and D-serine on MK-801-induced immobility in the forced swimming test in rats.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Clozapine; Disease Models, Animal; Dizocilpine Maleate; Glycine; Glycine Plasma Membrane Transport Proteins; Haloperidol; Imipramine; Locomotion; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sarcosine; Schizophrenia; Serine; Swimming | 2015 |
Bioinformatics analysis of the serine and glycine pathway in cancer cells.
Topics: Animals; Computational Biology; Genomics; Glycine; Humans; Mice; Neoplasms; Serine; Survival Analysis | 2014 |
Characterization of the usage of the serine metabolic network in human cancer.
Topics: Carbon; Gene Expression Regulation, Neoplastic; Glutathione; Glycine; Humans; Metabolic Flux Analysis; Metabolic Networks and Pathways; Models, Biological; Neoplasms; Nucleotides; Purines; Pyrimidines; Serine | 2014 |
Improving lignocellulose degradation using xylanase-cellulase fusion protein with a glycine-serine linker.
Topics: Cellulase; Chelating Agents; Endo-1,4-beta Xylanases; Enzyme Activation; Glycine; Hydrolysis; Ions; Kinetics; Lignin; Metals; Models, Molecular; Protein Conformation; Recombinant Fusion Proteins; Serine | 2015 |
In vivo kinetics of formate metabolism in folate-deficient and folate-replete rats.
Topics: Animals; Choline; Dimethylglycine Dehydrogenase; Folic Acid; Folic Acid Deficiency; Formaldehyde; Formates; Glycine; Histidine; Liver; Male; Methionine; Mitochondria; Mitochondria, Liver; Oxygen; Rats; Rats, Sprague-Dawley; Sarcosine Dehydrogenase; Serine; Tetrahydrofolates | 2015 |
Markers of glutamate signaling in cerebrospinal fluid and serum from patients with bipolar disorder and healthy controls.
Topics: Adult; Bipolar Disorder; Female; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Serine | 2015 |
Pharmacological PPARα activation markedly alters plasma turnover of the amino acids glycine, serine and arginine in the rat.
Topics: Animals; Arginase; Arginine; Body Weight; Calorimetry, Indirect; Glycine; Liver; Male; Nitrogen; PPAR alpha; Pyrimidines; Rats; Serine | 2014 |
Muscle mitohormesis promotes cellular survival via serine/glycine pathway flux.
Topics: Animals; Cell Survival; Glycine; Hormesis; Humans; Ion Channels; Metabolic Networks and Pathways; Mice; Mice, Transgenic; Mitochondria, Muscle; Mitochondrial Proteins; Muscle Fibers, Fast-Twitch; Muscle Fibers, Skeletal; Muscle Proteins; Oxidative Stress; Serine; Signal Transduction; Transcriptome; Uncoupling Protein 1 | 2015 |
Distinct photorespiratory reactions are preferentially catalyzed by glutamate:glyoxylate and serine:glyoxylate aminotransferases in rice.
Topics: Biocatalysis; Glycine; Glyoxylates; Kinetics; Oryza; Plant Leaves; Recombinant Proteins; Serine; Transaminases | 2015 |
Identity of the NMDA receptor coagonist is synapse specific and developmentally regulated in the hippocampus.
Topics: Animals; Animals, Newborn; Astrocytes; CA1 Region, Hippocampal; Dentate Gyrus; Glycine; Hippocampus; Long-Term Potentiation; Male; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Synapses | 2015 |
RAGE gene polymorphism and environmental factor in the risk of oral cancer.
Topics: Adenine; Areca; Base Pairing; Base Sequence; Carcinogenesis; Case-Control Studies; Cytosine; Female; Gene Frequency; Gene-Environment Interaction; Genetic Predisposition to Disease; Genetic Variation; Glycation End Products, Advanced; Glycine; Guanine; Haplotypes; Humans; Male; Middle Aged; Mouth Neoplasms; Neoplasm Staging; Polymorphism, Single Nucleotide; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Factors; Sequence Deletion; Serine; Thymine; Tobacco Use | 2015 |
Essentials in the life process indicated by the self-referential genetic code.
Topics: Biological Evolution; Carbon; Cell Division; Dimerization; Genetic Code; Glycine; Glycine Hydroxymethyltransferase; Metabolic Networks and Pathways; Models, Genetic; Origin of Life; Protein Biosynthesis; Reproduction; RNA, Transfer, Amino Acid-Specific; Serine | 2014 |
D-serine uptake and release in PC-12 cells measured by chiral microchip electrophoresis-mass spectrometry.
Topics: Amino Acid Transport System ASC; Animals; Electrophoresis, Microchip; Glutamic Acid; Glycine; Mass Spectrometry; Neurons; PC12 Cells; Potassium Chloride; Rats; Serine; Stereoisomerism | 2015 |
Genome-wide association study of NMDA receptor coagonists in human cerebrospinal fluid and plasma.
Topics: Adolescent; Adult; Alanine; Chromatography, Liquid; Female; Genetic Variation; Genome-Wide Association Study; Glycine; Humans; Male; Membrane Transport Proteins; Middle Aged; Proline; Proline Oxidase; Quantitative Trait Loci; Receptors, N-Methyl-D-Aspartate; Serine; Tandem Mass Spectrometry; Young Adult | 2015 |
Kinetic mechanism and the rate-limiting step of Plasmodium vivax serine hydroxymethyltransferase.
Topics: Folic Acid; Glycine; Glycine Hydroxymethyltransferase; Hydrogen-Ion Concentration; Kinetics; Plasmodium vivax; Protein Binding; Protozoan Proteins; Serine; Thermodynamics | 2015 |
Genetic association of ARHGAP21 gene variant with mandibular prognathism.
Topics: Adolescent; Adult; Aged; Annexin A2; Bone Morphogenetic Protein 3; Child; Exome; Female; Filamins; Genes, Dominant; Genetic Association Studies; Genetic Linkage; Genetic Variation; Genotype; Glycine; GTPase-Activating Proteins; Homeodomain Proteins; Humans; Male; Malocclusion, Angle Class III; Meiosis; Middle Aged; Mutation, Missense; Pedigree; Penetrance; Prognathism; Sequence Analysis, DNA; Serine; Young Adult | 2015 |
Adenoviral-mediated expression of G2019S LRRK2 induces striatal pathology in a kinase-dependent manner in a rat model of Parkinson's disease.
Topics: Adenoviridae; alpha-Synuclein; Animals; Corpus Striatum; Disease Models, Animal; Female; Forelimb; Gene Expression Regulation; Glycine; HEK293 Cells; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Parkinson Disease; Phosphopyruvate Hydratase; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Serine; Time Factors; Transduction, Genetic; Tubulin | 2015 |
The alanine-serine-cysteine-1 (Asc-1) transporter controls glycine levels in the brain and is required for glycinergic inhibitory transmission.
Topics: Amino Acid Transport System y+; Animals; Biological Transport; Brain; Genotype; Glycine; Hypoglossal Nerve; Metabolome; Metabolomics; Mice; Mice, Knockout; Mutation; Neurons; Phenotype; Receptors, Glycine; Serine; Synaptic Transmission | 2015 |
Exogenous glycine and serine promote growth and antifungal activity of Penicillium citrinum W1 from the south-west Indian Ocean.
Topics: Antifungal Agents; Fungal Proteins; Geologic Sediments; Glycine; Indian Ocean; Metabolic Networks and Pathways; Metabolome; Penicillium; Serine; Threonine | 2015 |
Neuronal serine racemase regulates extracellular D-serine levels in the adult mouse hippocampus.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Extracellular Space; Glutamic Acid; Glycine; Hippocampus; Mice, Knockout; Microdialysis; N-Methylaspartate; Neurons; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Serine; Taurine | 2015 |
Site-selective modification of peptides: From "customizable units" to novel α-aryl and α-alkyl glycine derivatives, and components of branched peptides.
Topics: Glycine; Peptides; Serine; Small Molecule Libraries; Substrate Specificity; Threonine | 2015 |
The crystal structure of D-threonine aldolase from Alcaligenes xylosoxidans provides insight into a metal ion assisted PLP-dependent mechanism.
Topics: Acetaldehyde; Alanine Racemase; Alcaligenes; Aldehyde-Lyases; Bacterial Proteins; Binding Sites; Catalysis; Catalytic Domain; Cloning, Molecular; Crystallization; Crystallography, X-Ray; Escherichia coli; Glycine; Manganese; Models, Molecular; Molecular Docking Simulation; Molecular Sequence Data; Multigene Family; Protein Conformation; Protein Structure, Tertiary; Protons; Pyridoxal Phosphate; Recombinant Proteins; Serine; Structure-Activity Relationship; Threonine | 2015 |
A quantitative study of the interactive effects of glycine and serine with threonine and choline on growth performance in broilers.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Choline; Diet; Dietary Supplements; Digestion; Glycine; Intestinal Mucosa; Male; Random Allocation; Serine; Threonine | 2015 |
Chemiluminescence Detection of Serine, Proline, Glycine, Asparagine, Leucine, and Histidine by Using Corresponding Aminoacyl-tRNA Synthetases as Recognition Elements.
Topics: Amino Acyl-tRNA Synthetases; Asparagine; Biological Assay; Buffers; Glycine; Histidine; Humans; Leucine; Luminescence; Luminescent Measurements; Luminol; Proline; Sensitivity and Specificity; Serine; Solutions; Water | 2015 |
A Protein Extract from Chicken Reduces Plasma Homocysteine in Rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Caseins; Chickens; Choline; Cystathionine gamma-Lyase; Cysteine; Dietary Proteins; Folic Acid; Glycine; Homocysteine; Liver; Male; Meat; Methionine; Rats; Rats, Wistar; Riboflavin; RNA, Messenger; Sarcosine; Serine; Vitamin B 12; Vitamin B 6 | 2015 |
Physiologically relevant factors influence tau phosphorylation by leucine-rich repeat kinase 2.
Topics: Animals; Antibody Specificity; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Manganese; Mutation; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Serine; tau Proteins; Threonine | 2015 |
Relationship between synovial fluid ARGS-aggrecan fragments, cytokines, MMPs, and TIMPs following acute ACL injury: A cross-sectional study.
Topics: Adolescent; Adult; Aggrecans; Alanine; Anterior Cruciate Ligament Injuries; Arginine; Body Mass Index; Cartilage, Articular; Cross-Sectional Studies; Cytokines; Epitopes; Female; Fibroblast Growth Factor 2; Gene Expression Regulation; Glycine; Humans; Inflammation; Knee Injuries; Male; Matrix Metalloproteinases; Prospective Studies; Serine; Synovial Fluid; Tissue Inhibitor of Metalloproteinase-3; Young Adult | 2015 |
Arginylation regulates purine nucleotide biosynthesis by enhancing the activity of phosphoribosyl pyrophosphate synthase.
Topics: Aminoacyltransferases; Animals; Arginine; Blotting, Western; Cell Line; Glycine; HEK293 Cells; Humans; Lysine; Mice; Mice, Knockout; Molecular Structure; Protein Processing, Post-Translational; Purine Nucleotides; Reverse Transcriptase Polymerase Chain Reaction; Ribose-Phosphate Pyrophosphokinase; RNA, Messenger; Serine; Ubiquitination | 2015 |
Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users.
Topics: 3-Hydroxyanthranilic Acid; Adult; Biomarkers; Carbon; Contraceptives, Oral; Cystathionine; Dietary Supplements; Female; Glycine; Homocysteine; Humans; Kynurenine; Leucine; Methionine; Methylamines; Multivariate Analysis; Pyridoxal Phosphate; Pyridoxine; Serine; Tryptophan; Vitamin B 6 Deficiency; Young Adult | 2015 |
Metabolomics strategy reveals therapeutical assessment of limonin on nonbacterial prostatitis.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Capsaicin; Disease Models, Animal; Glycerophospholipids; Glycine; Limonins; Male; Metabolomics; Prostatitis; Rats; Rats, Wistar; Serine; Threonine | 2015 |
CD and NMR investigation of collagen peptides mimicking a pathological Gly-Ser mutation and a natural interruption in a similar highly charged sequence context.
Topics: Amino Acid Sequence; Amino Acid Substitution; Circular Dichroism; Collagen; Glycine; Humans; Hydrogen Bonding; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptides; Point Mutation; Protein Folding; Protein Stability; Protein Structure, Secondary; Serine; Temperature | 2016 |
Nitrate and amino acid availability affects glycine betaine and mycosporine-2-glycine in response to changes of salinity in a halotolerant cyanobacterium Aphanothece halophytica.
Topics: Amino Acids; Bacterial Proteins; Betaine; Cyanobacteria; Cyclohexanols; Glycine; Nitrates; Salinity; Salt Tolerance; Serine; Stress, Physiological | 2015 |
Increased serum levels of serine enantiomers in patients with depression.
Topics: Adult; Biomarkers; Case-Control Studies; Depression; Female; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Serine; Stereoisomerism; Young Adult | 2016 |
Unlike pregnant adult women, pregnant adolescent girls cannot maintain glycine flux during late pregnancy because of decreased synthesis from serine.
Topics: Adolescent; Adult; Female; Glycine; Humans; Maternal Nutritional Physiological Phenomena; Models, Biological; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Third; Serine | 2016 |
D-Serine and Glycine Differentially Control Neurotransmission during Visual Cortex Critical Period.
Topics: Animals; Glutamic Acid; Glycine; Long-Term Potentiation; Male; Neuronal Plasticity; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Synaptic Transmission; Visual Cortex | 2016 |
Inhibition of homocysteine-induced endoplasmic reticulum stress and endothelial cell damage by l-serine and glycine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Apoptosis; Cell Line; Cell Survival; Cystathionine beta-Synthase; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Endothelial Cells; Glycine; Glycine Hydroxymethyltransferase; Heat-Shock Proteins; Homocysteine; Humans; RNA Interference; RNA, Small Interfering; Serine; Transcription Factor CHOP; X-Box Binding Protein 1 | 2016 |
Removal of the Side Chain at the Active-Site Serine by a Glycine Substitution Increases the Stability of a Wide Range of Serine β-Lactamases by Relieving Steric Strain.
Topics: beta-Lactamases; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Enzyme Stability; Escherichia coli; Glycine; Hydrolysis; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Serine | 2016 |
Modulation of glycine sites enhances social memory in rats using PQQ combined with d-serine.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Drug Contamination; Drug Synergism; Glycine; Haloperidol; Male; Memory; Memory Disorders; Neuroprotective Agents; PQQ Cofactor; Rats; Rats, Sprague-Dawley; Serine; Social Behavior; Time Factors | 2016 |
Effects of straight alkyl chain, extra hydroxylated alkyl chain and branched chain amino acids on gastric emptying evaluated using a non-invasive breath test in conscious rats.
Topics: Acetic Acid; Administration, Oral; Alanine; Amino Acids; Amino Acids, Branched-Chain; Animals; Breath Tests; Consciousness; Gastric Emptying; Glycine; Isoleucine; Leucine; Male; Rats, Sprague-Dawley; Serine; Threonine; Valine | 2016 |
Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway.
Topics: Aminoimidazole Carboxamide; Carbon; Cell Compartmentation; Cell Proliferation; Colonic Neoplasms; CRISPR-Cas Systems; Cytosol; Folic Acid; Formates; Gene Knockout Techniques; Gene Library; Glycine; Glycine Hydroxymethyltransferase; HCT116 Cells; HEK293 Cells; Humans; Leucovorin; Metabolic Networks and Pathways; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondria; Mutation; NADP; Ribonucleotides; Serine; Xenograft Model Antitumor Assays | 2016 |
Identification of Serum Metabolites Associated With Incident Hypertension in the European Prospective Investigation into Cancer and Nutrition-Potsdam Study.
Topics: Adult; Biomarkers; Early Diagnosis; Female; Germany; Glycine; Humans; Hypertension; Male; Metabolic Networks and Pathways; Metabolomics; Middle Aged; Nutrition Surveys; Phosphatidylcholines; Predictive Value of Tests; Prognosis; Prospective Studies; Risk Assessment; Risk Factors; Serine | 2016 |
Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53.
Topics: Activating Transcription Factor 4; Animals; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Cell Proliferation; Chromatin; Chromatin Assembly and Disassembly; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Glycine; HCT116 Cells; Homeostasis; Humans; Lung Neoplasms; Membrane Proteins; Mice, Nude; Mutation; Oxidation-Reduction; Oxidative Stress; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-mdm2; RNA Interference; Serine; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Time Factors; Transcription, Genetic; Transfection; Tumor Burden; Tumor Suppressor Protein p53 | 2016 |
Expression of serine/glycine metabolism-related proteins is different according to the thyroid cancer subtype.
Topics: Carcinoma; Carcinoma, Papillary; Disease-Free Survival; Glutamine; Glycine; Humans; Mutation; Neoplasm Proteins; Prognosis; Serine; Thyroid Cancer, Papillary; Thyroid Neoplasms | 2016 |
A novel mechanism of mTORC1-mediated serine/glycine metabolism in osteosarcoma development.
Topics: Apoptosis; Carbon; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Glycine; Humans; Mechanistic Target of Rapamycin Complex 1; Models, Biological; Osteosarcoma; Oxidation-Reduction; Serine; Signal Transduction | 2017 |
'Rod and ring' formation from IMP dehydrogenase is regulated through the one-carbon metabolic pathway.
Topics: Aminopterin; Carbon; Culture Media; Gene Knockdown Techniques; Glycine; Glycine Hydroxymethyltransferase; Guanosine; HeLa Cells; Humans; Hypoxanthine; IMP Dehydrogenase; Metabolic Networks and Pathways; Methotrexate; RNA, Small Interfering; Serine; Tetrahydrofolate Dehydrogenase | 2016 |
Repression of phosphoglycerate dehydrogenase sensitizes triple-negative breast cancer to doxorubicin.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Doxorubicin; Female; Glutathione; Glycine; Humans; Mass Spectrometry; Mice; Neoplasms, Experimental; Oxidative Stress; Phosphoglycerate Dehydrogenase; Reactive Oxygen Species; RNA, Small Interfering; Serine; Triple Negative Breast Neoplasms | 2016 |
Influence of amino acids on gastric adaptive relaxation (accommodation) in rats as evaluated with a barostat.
Topics: Adaptation, Physiological; Administration, Oral; Amino Acids; Animals; Dyspepsia; Glycine; Injections, Intravenous; Male; Manometry; Muscle Relaxation; Muscle, Smooth; Rats, Sprague-Dawley; Serine; Stimulation, Chemical; Stomach | 2016 |
Endogenous co-agonists of the NMDA receptor modulate contextual fear in trace conditioning.
Topics: Animals; Conditioning, Classical; Cues; Fear; Glycine; Glycine Plasma Membrane Transport Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Serine | 2016 |
Detection of a phosphorylated glycine-serine linker in an IgG-based fusion protein.
Topics: Animals; Antibodies, Bispecific; Cell Line; CHO Cells; Cricetinae; Cricetulus; Glycine; Humans; Immunoglobulin G; Phosphorylation; Protein Engineering; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Serine | 2017 |
LKB1 loss links serine metabolism to DNA methylation and tumorigenesis.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Cell Culture Techniques; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromatin; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Epithelial Cells; Gene Silencing; Genes, Tumor Suppressor; Glycine; Glycolysis; Humans; Mice; Pancreatic Ducts; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins p21(ras); Retroelements; S-Adenosylmethionine; Serine; TOR Serine-Threonine Kinases; Transaminases | 2016 |
Association of the DRD2 CA
Topics: Aged; Aged, 80 and over; Analysis of Variance; Benzothiazoles; Case-Control Studies; Dinucleotide Repeats; Dopamine Agonists; Female; Genotype; Glycine; Humans; Male; Middle Aged; Parkinson Disease; Polymorphism, Single Nucleotide; Pramipexole; Receptors, Dopamine D2; Receptors, Dopamine D3; Serine | 2017 |
An archaeal ADP-dependent serine kinase involved in cysteine biosynthesis and serine metabolism.
Topics: Archaeal Proteins; Cysteine; Gene Expression Regulation, Archaeal; Gene Expression Regulation, Enzymologic; Glycine; Protein Serine-Threonine Kinases; Serine; Thermococcus; Threonine | 2016 |
Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells.
Topics: Acetyl Coenzyme A; Aspartic Acid; Biosynthetic Pathways; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Citric Acid; Female; Gene Knockdown Techniques; Glycine; Glycolysis; Humans; Lactic Acid; Malates; Mass Spectrometry; Metabolic Networks and Pathways; Neoplasm Invasiveness; Nucleotides; Pyruvate Carboxylase; Pyruvic Acid; Serine | 2017 |
Heart rate variability in leucine-rich repeat kinase 2-associated Parkinson's disease.
Topics: Aged; Electrocardiography; Female; Genetic Association Studies; Glycine; Heart Diseases; Heart Rate; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Serine; Severity of Illness Index | 2017 |
Serine Is an Essential Metabolite for Effector T Cell Expansion.
Topics: Animals; Carbon; Cell Cycle Checkpoints; Cell Proliferation; Diet; Energy Metabolism; Extracellular Space; Glycine; Listeria monocytogenes; Metabolic Networks and Pathways; Metabolome; Mice, Inbred C57BL; Purine Nucleotides; Serine; T-Lymphocytes | 2017 |
Charcot-Marie-Tooth disease type 1C: Clinical and electrophysiological findings for the c.334G>a (p.Gly112Ser) Litaf/Simple mutation.
Topics: Adolescent; Adult; Aged; Charcot-Marie-Tooth Disease; Child; Child, Preschool; Electrophysiological Phenomena; Female; Glycine; Humans; Male; Middle Aged; Mutation; Nuclear Proteins; Retrospective Studies; Serine; Transcription Factors; Young Adult | 2017 |
Metagenomics approach to the study of the gut microbiome structure and function in zebrafish Danio rerio fed with gluten formulated diet.
Topics: Animals; Bacteria; Bile Acids and Salts; Biodiversity; Computational Biology; Diet; DNA, Bacterial; Ecosystem; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Tract; Genes, Bacterial; Glutens; Glycine; Metagenomics; Microbial Consortia; Models, Animal; Phylogeny; RNA, Ribosomal, 16S; Serine; Threonine; Vitamin B 12; Zebrafish | 2017 |
Differential regulation of NMDA receptors by d-serine and glycine in mammalian spinal locomotor networks.
Topics: 2-Amino-5-phosphonovalerate; Animals; Efferent Pathways; Glycine; Interneurons; Kynurenic Acid; Mice; Mice, Inbred C57BL; Motor Activity; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Spinal Nerve Roots; Synapses | 2017 |
Dysregulated Glycine Signaling Contributes to Increased Impulsivity during Protracted Alcohol Abstinence.
Topics: Alcohol Abstinence; Alcohol Drinking; Animals; Central Nervous System Depressants; Choice Behavior; Disease Models, Animal; Ethanol; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glycine; Impulsive Behavior; Male; Neurotransmitter Agents; Photic Stimulation; Quinolones; Rats; Rats, Wistar; Reaction Time; Sarcosine; Serine; Signal Transduction | 2017 |
Personal model-assisted identification of NAD
Topics: Animals; Disease Models, Animal; Female; Gene Expression Regulation, Enzymologic; Genome; Glutathione; Glycine; Humans; Lipoproteins; Liver; Male; Metabolomics; Mice; Middle Aged; NAD; Non-alcoholic Fatty Liver Disease; Patient-Specific Modeling; Serine | 2017 |
2-methoxyestradiol impacts on amino acids-mediated metabolic reprogramming in osteosarcoma cells by its interaction with NMDA receptor.
Topics: 2-Methoxyestradiol; Antineoplastic Agents; Binding Sites; Bone Neoplasms; Breast Neoplasms; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Energy Metabolism; Estradiol; Female; Glycine; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial; Molecular Docking Simulation; Molecular Dynamics Simulation; Nerve Tissue Proteins; Nitric Oxide Synthase Type I; Osteosarcoma; Protein Binding; Protein Domains; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Structure-Activity Relationship; Time Factors; Tubulin Modulators | 2017 |
When cancer needs what's non-essential.
Topics: Animals; Cell Proliferation; Diet, Protein-Restricted; Energy Metabolism; Glycine; Humans; Mice; Neoplasms; Serine | 2017 |
Modulating the therapeutic response of tumours to dietary serine and glycine starvation.
Topics: Animals; Antioxidants; Biguanides; Cell Line, Tumor; Diet; Disease Models, Animal; Female; Food Deprivation; Glycine; Humans; Intestinal Neoplasms; Lymphoma; Male; Mice; Mitochondria; Nutritional Status; Oxidative Phosphorylation; Pancreatic Neoplasms; Proto-Oncogene Proteins p21(ras); Serine; Survival Rate | 2017 |
A Synthetic Alternative to Canonical One-Carbon Metabolism.
Topics: Acetoacetates; Carbon; Escherichia coli; Escherichia coli Proteins; Genetic Enhancement; Glycine; Metabolic Engineering; Metabolic Networks and Pathways; Pyruvic Acid; Serine; Synthetic Biology | 2017 |
Enhancement of 5-aminolevulinic acid production by metabolic engineering of the glycine biosynthesis pathway in Corynebacterium glutamicum.
Topics: Aminolevulinic Acid; Biosynthetic Pathways; Carbon; Corynebacterium glutamicum; Gene Expression; Genetic Vectors; Glucose; Glycine; Metabolic Engineering; Plasmids; Rhodobacter sphaeroides; Serine | 2017 |
Can Simple Interaction Models Explain Sequence-Dependent Effects in Peptide Homodimerization?
Topics: Glycine; Hydrophobic and Hydrophilic Interactions; Leucine; Models, Molecular; Peptides; Protein Multimerization; Serine | 2017 |
Exploiting tumour addiction with a serine and glycine-free diet.
Topics: Diet; Glycine; Humans; Neoplasms; Serine | 2017 |
Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses.
Topics: Animals; Glycine; Hippocampus; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Synapses | 2017 |
Identification of YfiH (PgeF) as a factor contributing to the maintenance of bacterial peptidoglycan composition.
Topics: Alanine; Amino Acids; Bacterial Proteins; Cell Wall; Conserved Sequence; Escherichia coli; Escherichia coli Proteins; Glycine; Peptidoglycan; Serine | 2017 |
Penetrance estimate of LRRK2 p.G2019S mutation in individuals of non-Ashkenazi Jewish ancestry.
Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Family Health; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Glycine; Humans; Jews; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Penetrance; Serine | 2017 |
Dietary methionine source and level affect hepatic sulfur amino acid metabolism of broiler breeder hens.
Topics: Adenosine Deaminase; Alanine; Amino Acids, Sulfur; Animals; Butyrates; Chickens; Diet; Dietary Supplements; Female; Gene Expression; Glycine; Liver; Methionine; Methionine Adenosyltransferase; Serine; Tyrosine; Valine | 2017 |
Vitamin B6 is essential for serine de novo biosynthesis.
Topics: Brain; Cells, Cultured; Glycine; Humans; Pyridoxal Phosphate; Pyridoxine; Serine; Vitamin B 6; Vitamin B 6 Deficiency | 2017 |
Quantification of Photorespiratory Intermediates by Mass Spectrometry-Based Approaches.
Topics: Arabidopsis; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Glyceric Acids; Glycine; Glycolates; Glyoxylates; Mass Spectrometry; Oxidation-Reduction; Oxygen Consumption; Photosynthesis; Plant Leaves; Pyruvates; Reference Standards; Ribulose-Bisphosphate Carboxylase; Serine | 2017 |
Topics: Arabidopsis; Carbon Dioxide; Carbon Isotopes; Chloroplasts; Cytosol; Gas Chromatography-Mass Spectrometry; Glyceric Acids; Glycine; Glycolates; Isotope Labeling; Kinetics; Mitochondria; Oxygen; Oxygen Consumption; Peroxisomes; Photosynthesis; Plant Leaves; Ribulose-Bisphosphate Carboxylase; Serine | 2017 |
A NMDA-receptor calcium influx assay sensitive to stimulation by glutamate and glycine/D-serine.
Topics: Calcium; Gene Expression; Glutamic Acid; Glycine; HEK293 Cells; Humans; Protein Binding; Protein Multimerization; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Serine | 2017 |
Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis.
Topics: Airway Remodeling; Animals; Bleomycin; Collagen; Disease Models, Animal; Enzyme Inhibitors; Fibroblasts; Glycine; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Mice; Mice, Inbred C57BL; NIH 3T3 Cells; Phosphoglycerate Dehydrogenase; Serine; Signal Transduction; Transforming Growth Factor beta | 2018 |
L-Glycine Alleviates Furfural-Induced Growth Inhibition during Isobutanol Production in Escherichia coli.
Topics: Biofuels; Biomass; Butanols; Culture Media; Escherichia coli; Fermentation; Furaldehyde; Glycine; Inhibitory Concentration 50; Lignin; Serine | 2017 |
Clinical and neuropathological features of progressive supranuclear palsy in Leucine rich repeat kinase (LRRK2) G2019S mutation carriers.
Topics: Aged; Astrocytes; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Locus Coeruleus; Male; Mutation; Serine; Supranuclear Palsy, Progressive; tau Proteins | 2018 |
Tuning the Flexibility of Glycine-Serine Linkers To Allow Rational Design of Multidomain Proteins.
Topics: Computer Simulation; Dipeptides; Fluorescence Resonance Energy Transfer; Glycine; Molecular Conformation; Peptides; Protein Domains; Protein Engineering; Proteins; Serine | 2017 |
Increased Phosphorylation of Ser-Gln Sites on SUPPRESSOR OF GAMMA RESPONSE1 Strengthens the DNA Damage Response in
Topics: Amino Acid Motifs; Apoptosis; Arabidopsis; Arabidopsis Proteins; Bleomycin; Cell Cycle; Cell Differentiation; DNA Damage; DNA Repair; DNA Replication; Gamma Rays; Gene Expression Regulation, Plant; Gene Ontology; Genes, Plant; Glycine; Mutant Proteins; Phosphorylation; Plant Roots; Serine; Transcription Factors | 2017 |
Decrease of superficial serine and lactate in the stratum corneum due to repetitive frictional trauma.
Topics: Adult; Arginine; Epidermis; Female; Friction; Glycine; Humans; Lactates; Male; Serine; Skin Physiological Phenomena; Spectrum Analysis, Raman; Water Loss, Insensible | 2018 |
DRD3 Ser9Gly Polymorphism and Its Influence on Risperidone Response in Autistic Children.
Topics: Adolescent; Alleles; Autistic Disorder; Child; Child, Preschool; Female; Genotype; Glycine; Humans; Iran; Male; Polymorphism, Genetic; Receptors, Dopamine D3; Risperidone; Serine; Software; Treatment Outcome | 2017 |
Long-term follow up of an adult with alternating hemiplegia of childhood and a p.Gly755Ser mutation in the ATP1A3 gene.
Topics: Adult; Female; Glycine; Hemiplegia; Humans; Longitudinal Studies; Mutation; Neuroimaging; Phenotype; Serine; Sodium-Potassium-Exchanging ATPase | 2018 |
Disturbed phospholipid metabolism in serine biosynthesis defects revealed by metabolomic profiling.
Topics: Carbohydrate Metabolism, Inborn Errors; Cell Differentiation; Child; Child, Preschool; Dietary Supplements; Female; Glycine; Humans; Infant; Male; Metabolomics; Microcephaly; Neurons; Phosphatidylcholines; Phosphoglycerate Dehydrogenase; Psychomotor Disorders; Seizures; Serine; Transaminases | 2018 |
Astrocytes in primary cultures express serine racemase, synthesize d-serine and acquire A1 reactive astrocyte features.
Topics: Animals; Astrocytes; Cells, Cultured; Complement C3a; Culture Media; Glycine; Glycine Dehydrogenase (Decarboxylating); Lipocalin-2; Mice; Mice, Knockout; Primary Cell Culture; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Serine | 2018 |
Reprogramming One-Carbon Metabolic Pathways To Decouple l-Serine Catabolism from Cell Growth in Corynebacterium glutamicum.
Topics: Computer Simulation; Corynebacterium glutamicum; Escherichia coli; Escherichia coli Proteins; Glycine; Glycine Hydroxymethyltransferase; Metabolic Engineering; Models, Biological; Serine | 2018 |
Cobalamin Deficiency Results in Increased Production of Formate Secondary to Decreased Mitochondrial Oxidation of One-Carbon Units in Rats.
Topics: Animals; Carbon; Carbon Dioxide; Cytosol; Folic Acid; Formates; Glycine; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Random Allocation; Rats, Sprague-Dawley; S-Adenosylmethionine; Sarcosine; Serine; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Type III collagen affects dermal and vascular collagen fibrillogenesis and tissue integrity in a mutant Col3a1 transgenic mouse model.
Topics: Amino Acid Substitution; Animals; Arteries; Collagen Type III; Disease Models, Animal; Ehlers-Danlos Syndrome; Female; Fibroblasts; Gene Expression; Glycine; Heterozygote; Humans; Male; Mice; Mice, Transgenic; Mutation; Serine; Sex Factors; Skin; Tissue Culture Techniques | 2018 |
Electrical-biological hybrid system for CO
Topics: Carbon Dioxide; Escherichia coli; Formates; Glycine; Metabolic Engineering; Microorganisms, Genetically-Modified; Oxidation-Reduction; Pyruvic Acid; Serine | 2018 |
Application of the Movement Disorder Society prodromal criteria in healthy G2019S-LRRK2 carriers.
Topics: Adult; Aged; Aged, 80 and over; Female; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Longitudinal Studies; Male; Middle Aged; Movement Disorders; Mutation; Prodromal Symptoms; Serine; Societies, Medical; Young Adult | 2018 |
Clustering of motor and nonmotor traits in leucine-rich repeat kinase 2 G2019S Parkinson's disease nonparkinsonian relatives: A multicenter family study.
Topics: Adult; Aged; Cohort Studies; Cross-Sectional Studies; Family; Family Health; Female; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Serine | 2018 |
Why is vitamin B6 effective in alleviating the symptoms of autism?
Topics: Autistic Disorder; Dopamine; gamma-Aminobutyric Acid; Glycine; Histamine; Humans; Models, Neurological; Neurotransmitter Agents; Norepinephrine; Serine; Serotonin; Synaptic Transmission; Vitamin B 6 | 2018 |
Identification and efficacy of glycine, serine and threonine metabolism in potentiating kanamycin-mediated killing of Edwardsiella piscicida.
Topics: Amino Acids; Anti-Bacterial Agents; Drug Resistance, Bacterial; Drug Synergism; Edwardsiella; Glucose; Glycine; Kanamycin; Serine; Threonine | 2018 |
In Vivo Assimilation of One-Carbon via a Synthetic Reductive Glycine Pathway in Escherichia coli.
Topics: Amino Acid Oxidoreductases; Carbon; Carbon Dioxide; Carrier Proteins; Escherichia coli; Formates; Glycine; Multienzyme Complexes; Serine; Tetrahydrofolates; Transferases | 2018 |
EWS-FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine-glycine biosynthesis.
Topics: Amino Acid Transport System ASC; Aminohydrolases; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Formate-Tetrahydrofolate Ligase; Gene Expression Regulation, Neoplastic; Glutamine; Glycine; HCT116 Cells; HEK293 Cells; Humans; Methylenetetrahydrofolate Dehydrogenase (NADP); Minor Histocompatibility Antigens; Multienzyme Complexes; Multifunctional Enzymes; Oncogene Proteins, Fusion; Phosphoglycerate Dehydrogenase; Proto-Oncogene Protein c-fli-1; RNA-Binding Protein EWS; Sarcoma, Ewing; Serine | 2018 |
Shift from stochastic to spatially-ordered expression of serine-glycine synthesis enzymes in 3D microtumors.
Topics: Cell Communication; Cell Line, Tumor; Cell Proliferation; Ecosystem; Glycine; Humans; Ki-67 Antigen; Models, Theoretical; Phosphoglycerate Dehydrogenase; Serine | 2018 |
Prediction of Rare Palmitoylation Events in Proteins.
Topics: Algorithms; Cysteine; Glycine; Humans; Lipoylation; Palmitic Acid; Position-Specific Scoring Matrices; Protein Processing, Post-Translational; Proteins; Proteome; Serine; Support Vector Machine | 2018 |
Glyphosate Resistance in Tridax procumbens via a Novel EPSPS Thr-102-Ser Substitution.
Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Amino Acid Motifs; Amino Acid Substitution; Asteraceae; Glycine; Glyphosate; Herbicide Resistance; Herbicides; Mutation, Missense; Phosphoenolpyruvate; Plant Proteins; Serine; Threonine | 2018 |
Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes.
Topics: Apoptosis; Cell Line, Tumor; Enzyme Inhibitors; Glycine; Glycine Hydroxymethyltransferase; Humans; Hydrogen Bonding; Lung Neoplasms; Pyrans; Pyrazoles; Serine; Spectrometry, Fluorescence; Substrate Specificity | 2018 |
Both reentrant loops of the sodium-coupled glutamate transporters contain molecular determinants of cation selectivity.
Topics: Binding Sites; Cations; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glycine; HeLa Cells; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Serine; Sodium | 2018 |
The G2019S mutation in LRRK2 imparts resiliency to kinase inhibition.
Topics: Adenosine Triphosphate; Animals; Brain; Female; Glycine; Humans; Indazoles; Kidney; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Lung; Lysosomes; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Serine | 2018 |
Early life esophageal acid exposure reduces expression of NMDAR1 in the adult rat dorsal hippocampus and medial prefrontal cortex: Potential relationship with hyperlocomotion.
Topics: Animals; Animals, Newborn; Behavior, Animal; Claudin-1; Esophageal Mucosa; Glycine; Hippocampus; Hydrochloric Acid; Locomotion; Male; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Tight Junctions | 2018 |
A High-throughput Calcium-flux Assay to Study NMDA-receptors with Sensitivity to Glycine/D-serine and Glutamate.
Topics: Calcium; Glutamic Acid; Glycine; HEK293 Cells; Humans; Receptors, N-Methyl-D-Aspartate; Serine | 2018 |
Inhibitors of the Neutral Amino Acid Transporters ASCT1 and ASCT2 Are Effective in In Vivo Models of Schizophrenia and Visual Dysfunction.
Topics: Amino Acid Transport System ASC; Animals; Brain; Glycine; Locomotion; Male; Mice; Mice, Inbred C57BL; Minor Histocompatibility Antigens; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Vision Disorders | 2018 |
ASCT1 (Slc1a4) transporter is a physiologic regulator of brain d-serine and neurodevelopment.
Topics: Amino Acid Transport System ASC; Animals; Astrocytes; Brain; Cell Communication; Disease Models, Animal; Glycine; HEK293 Cells; Humans; Long-Term Potentiation; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcephaly; Minor Histocompatibility Antigens; Neurons; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission | 2018 |
Asc-1 transporter activation: an alternative to rescue age-related alterations in functional plasticity at rat hippocampal CA3/CA1 synapses.
Topics: Aging; Amino Acid Transport System ASC; Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Electrophysiological Phenomena; Glycine; Long-Term Potentiation; Male; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission | 2018 |
Glyphosate induces the synthesis of ppGpp.
Topics: Amino Acids, Aromatic; Escherichia coli; Escherichia coli Proteins; Glycine; Glyphosate; Guanosine Tetraphosphate; Ligases; Mutation; Serine | 2019 |
Bioformation of Volatile and Nonvolatile Metabolites by
Topics: Acetates; Alanine; Carbon; Glutamic Acid; Glycine; Isoleucine; Mannitol; Mannose; Phenylacetates; Phenylalanine; Phenylethyl Alcohol; Proline; Saccharomycopsis; Serine; Sugar Alcohols; Threonine; Time Factors | 2018 |
Analysis of glucose-derived amino acids involved in one-carbon and cancer metabolism by stable-isotope tracing gas chromatography mass spectrometry.
Topics: Amino Acids; Carbon; Carbon Isotopes; Cell Line, Tumor; Gas Chromatography-Mass Spectrometry; Glucose; Glycine; Humans; Methionine; Neoplasms; Serine | 2019 |
Human Cytosolic and Mitochondrial Serine Hydroxymethyltransferase Isoforms in Comparison: Full Kinetic Characterization and Substrate Inhibition Properties.
Topics: Cytosol; Glycine; Glycine Hydroxymethyltransferase; Humans; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Mitochondria; Models, Biological; Serine; Substrate Specificity; Tetrahydrofolates | 2018 |
Seminal plasma amino acid profile in different breeds of chicken: Role of seminal plasma on sperm cryoresistance.
Topics: Alanine; Amino Acids; Animals; Chickens; Cryopreservation; DNA Fragmentation; Glutamic Acid; Glycine; In Situ Nick-End Labeling; Male; Semen; Serine; Spermatozoa; Valine | 2019 |
A systematically-revised ribosome profiling method for bacteria reveals pauses at single-codon resolution.
Topics: Codon; Escherichia coli; Glycine; Protein Biosynthesis; Ribosomes; RNA, Messenger; Serine; Transfer RNA Aminoacylation | 2019 |
Phosphoglycerate dehydrogenase promotes pancreatic cancer development by interacting with eIF4A1 and eIF4E.
Topics: Animals; Antigens, CD; Cadherins; Cell Line, Tumor; Cell Proliferation; Eukaryotic Initiation Factor-4A; Eukaryotic Initiation Factor-4E; Gene Knockdown Techniques; Glycine; Heterografts; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Phosphoglycerate Dehydrogenase; Serine; Zonula Occludens-1 Protein | 2019 |
Design strategy for serine hydroxymethyltransferase probes based on retro-aldol-type reaction.
Topics: Aldehydes; Biomarkers; Crystallography, X-Ray; Fluorescent Dyes; Fluorine-19 Magnetic Resonance Imaging; Glycine; Glycine Hydroxymethyltransferase; High-Throughput Screening Assays; Humans; Molecular Probes; Serine; Tetrahydrofolates | 2019 |
Gamma-band auditory steady-state response is associated with plasma levels of d-serine in schizophrenia: An exploratory study.
Topics: Adolescent; Adult; Case-Control Studies; Electroencephalography; Evoked Potentials, Auditory; Female; GABAergic Neurons; Gamma Rhythm; Glutamic Acid; Glutamine; Glycine; Humans; Male; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Young Adult | 2019 |
Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion.
Topics: Aging; Animals; Caenorhabditis elegans; Diet; Genes, Helminth; Glycine; Longevity; Metabolic Networks and Pathways; Methionine; Mutation; RNA Interference; Serine; Transcriptome | 2019 |
A bacterial treasure trove.
Topics: Alkynes; Bacterial Proteins; Biosynthetic Pathways; Escherichia coli; Gene Deletion; Genomics; Glycine; Serine; Streptomyces | 2019 |
Metabolic Reprogramming by MYCN Confers Dependence on the Serine-Glycine-One-Carbon Biosynthetic Pathway.
Topics: Biosynthetic Pathways; Carbon; Cell Line, Tumor; Child; Glycine; Humans; N-Myc Proto-Oncogene Protein; Neuroblastoma; Serine | 2019 |
mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β
Topics: Activating Transcription Factor 4; Biosynthetic Pathways; Cell Differentiation; Cells, Cultured; Collagen; Extracellular Matrix; Fibroblasts; Gene Expression Regulation; Glycine; Humans; Mechanistic Target of Rapamycin Complex 1; Myofibroblasts; Serine; Signal Transduction; Transforming Growth Factor beta1 | 2019 |
Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells.
Topics: Animals; Cell Line; Gene Expression Profiling; Glycine; Mice; Mutation; Phosphoric Monoester Hydrolases; Polyribosomes; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Protein Biosynthesis; Ribosomal Protein L10; Ribosomal Proteins; Ribosomes; RNA, Messenger; Sequence Analysis, RNA; Serine | 2019 |
Subsaturation of the N-methyl-D-aspartate receptor glycine site allows the regulation of bursting activity in juvenile rat nigral dopamine neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dopaminergic Neurons; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; Kynurenic Acid; Pars Compacta; Phosphinic Acids; Propanolamines; Rats; Receptors, N-Methyl-D-Aspartate; Serine | 2019 |
Cuprizone-treated mice, a possible model of schizophrenia, highlighting the simultaneous abnormalities of GABA, serine and glycine in hippocampus.
Topics: Animals; Cuprizone; Disease Models, Animal; gamma-Aminobutyric Acid; Glycine; Hippocampus; Male; Metabolomics; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Schizophrenia; Serine | 2019 |
pH-dependent adsorption of α-amino acids, lysine, glutamic acid, serine and glycine, on TiO
Topics: Adsorption; Glutamic Acid; Glycine; Hydrogen-Ion Concentration; Lysine; Protein Corona; Serine; Titanium | 2019 |
Serine and 1-carbon metabolism are required for HIF-mediated protection against retinopathy of prematurity.
Topics: Animals; Carbon; Disease Models, Animal; Glycine; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Isoquinolines; Liver; Metabolic Networks and Pathways; Methotrexate; Mice; Mice, Knockout; Oxygen; Protein Stability; Retina; Retinopathy of Prematurity; Serine; Tissue Culture Techniques; Up-Regulation | 2019 |
Glycine, serine and threonine metabolism confounds efficacy of complement-mediated killing.
Topics: Adenosine Triphosphate; Bacterial Outer Membrane Proteins; Chaperonins; Citric Acid Cycle; Complement Membrane Attack Complex; Complement System Proteins; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Glycine; Humans; Purines; Serine; Serum; Threonine | 2019 |
Serine-Glycine-One-Carbon Metabolism: The Hidden Achilles Heel of
Topics: Carbon; Cell Line, Tumor; Glycine; Humans; N-Myc Proto-Oncogene Protein; Neuroblastoma; Nuclear Proteins; Oncogene Proteins; Serine | 2019 |
Hotspot SF3B1 mutations induce metabolic reprogramming and vulnerability to serine deprivation.
Topics: Animals; Cell Line, Tumor; Cellular Reprogramming; Energy Metabolism; Glycine; Humans; Mice; Mutation; Neoplasm Proteins; Neoplasms; Phosphoglycerate Dehydrogenase; Phosphoproteins; Proteome; RNA Splicing Factors; Serine; Transcriptome; Xenograft Model Antitumor Assays | 2019 |
Efficient production of glutathione with multi-pathway engineering in Corynebacterium glutamicum.
Topics: Corynebacterium glutamicum; Cysteine; Glutamic Acid; Glutathione; Glycine; Metabolic Engineering; Metabolic Networks and Pathways; Serine | 2019 |
Supplementing glycine, serine, and threonine in low protein diets for meat type chickens.
Topics: Animal Feed; Animals; Body Weight; Chickens; Diet, Protein-Restricted; Dietary Supplements; Glycine; Male; Random Allocation; Serine; Threonine | 2019 |
The NMDA receptor activation by d-serine and glycine is controlled by an astrocytic Phgdh-dependent serine shuttle.
Topics: Animals; Astrocytes; Glycine; Hippocampus; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Phosphoglycerate Dehydrogenase; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Serine; Synapses | 2019 |
ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer.
Topics: Animals; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Epidermal Growth Factor; Female; Gene Expression Regulation, Neoplastic; Glycine; Humans; Mice, Inbred BALB C; Mice, Nude; Nuclear Factor 90 Proteins; Nuclear Proteins; Prognosis; Protein Binding; Protein Stability; Repressor Proteins; RNA Stability; Serine; Substrate Specificity; Survival Analysis; Ubiquitin-Protein Ligases | 2020 |
Comparative Pro-cognitive and Neurochemical Profiles of Glycine Modulatory Site Agonists and Glycine Reuptake Inhibitors in the Rat: Potential Relevance to Cognitive Dysfunction and Its Management.
Topics: Amino Acids; Animals; Autism Spectrum Disorder; Cognition; Cognition Disorders; Cycloserine; Dose-Response Relationship, Drug; Freezing Reaction, Cataleptic; Glycine; Glycine Agents; Male; Memory, Short-Term; Motor Activity; Neurotransmitter Uptake Inhibitors; Nootropic Agents; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Sarcosine; Schizophrenia; Scopolamine; Serine; Social Behavior | 2020 |
Structural basis of second-generation HIV integrase inhibitor action and viral resistance.
Topics: Amides; Amino Acid Substitution; Catalytic Domain; Cryoelectron Microscopy; Drug Resistance, Viral; Glutamine; Glycine; Heterocyclic Compounds, 3-Ring; Heterocyclic Compounds, 4 or More Rings; Histidine; HIV Integrase; HIV Integrase Inhibitors; Humans; Magnesium; Mutation; Oxazines; Piperazines; Pyridones; Serine; Single Molecule Imaging | 2020 |
A Cuboid Spider Silk: Structure-Function Relationship and Polypeptide Signature.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Animals; Fibroins; Glycine; Materials Testing; Peptides; Protein Conformation, beta-Strand; Serine; Silk; Spiders; Structure-Activity Relationship | 2020 |
Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation.
Topics: Animals; Cell Polarity; Cell Proliferation; Gene Expression Regulation, Enzymologic; Genomics; Glutamic Acid; Glycine; Interleukin-4; Ketoglutaric Acids; Kinetics; Macrophages; Mechanistic Target of Rapamycin Complex 1; Mice, Inbred C57BL; Models, Biological; Phosphoglycerate Dehydrogenase; Principal Component Analysis; Serine; Tuberous Sclerosis Complex 2 Protein | 2020 |
Asc-1 Transporter (SLC7A10): Homology Models And Molecular Dynamics Insights Into The First Steps Of The Transport Mechanism.
Topics: Amino Acid Motifs; Amino Acid Transport System y+; Binding Sites; Biological Transport; Glycine; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Molecular Dynamics Simulation; Serine | 2020 |
Ichthyosis with confetti caused by new and recurrent mutations in KRT10 associated with varying degrees of keratin 10 mis-localization.
Topics: Adolescent; Amino Acid Sequence; Arginine; Biopsy; Cell Nucleus; Child, Preschool; DNA Mutational Analysis; Epidermis; Female; Frameshift Mutation; Glycine; HaCaT Cells; Humans; Ichthyosis; Keratin-10; Keratinocytes; Loss of Heterozygosity; Male; Serine | 2020 |
Feature of Heart Rate Variability and Metabolic Mechanism in Female College Students with Depression.
Topics: Adolescent; Autonomic Nervous System; Depression; Fatigue; Female; Glycine; Heart Rate; Humans; Metabolomics; Monitoring, Physiologic; Pyrimidines; Serine; Steroids; Stress, Physiological; Students; Threonine; Tyrosine; Ubiquinone; Urine; Young Adult | 2020 |
Nonclassical nuclear localization signals mediate nuclear import of CIRBP.
Topics: Active Transport, Cell Nucleus; Arginine; beta Karyopherins; Cell Nucleus; Cytoplasm; Glycine; HeLa Cells; Humans; Nuclear Localization Signals; Peptide Fragments; Protein Binding; Protein Conformation; RNA-Binding Proteins; Serine; Tyrosine | 2020 |
Maternal arginine supplementation enhances thermogenesis in the newborn lamb.
Topics: Adipose Tissue, Brown; Administration, Intravenous; Animals; Animals, Newborn; Arginine; Body Temperature; Cold Temperature; Dietary Supplements; Female; Glycine; Parturition; Pregnancy; Serine; Sheep; Thermogenesis | 2020 |
The effect of reduced dietary glycine and serine and supplemental threonine on growth performance, protein deposition in carcass and viscera, and skin collagen abundance of nursery pigs fed low crude protein diets.
Topics: Animal Feed; Animals; Body Composition; Collagen; Diet; Diet, Protein-Restricted; Dietary Proteins; Dietary Supplements; Glycine; Male; Serine; Skin; Skin Physiological Phenomena; Swine; Threonine; Viscera; Weight Gain | 2020 |
Untangling Determinants of Enhanced Health and Lifespan through a Multi-omics Approach in Mice.
Topics: Animals; Caloric Restriction; Fatty Acids, Unsaturated; Female; Glucose; Glucose Tolerance Test; Glycine; Longevity; Male; Metabolomics; Mice; Mice, Inbred C57BL; Serine; Threonine | 2020 |
Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition.
Topics: Animals; Antineoplastic Agents; Brain; Brain Neoplasms; Cell Line, Tumor; Datasets as Topic; Drug Resistance, Neoplasm; Female; Gene Knockdown Techniques; Glycine; Humans; Metabolomics; Mice; Phosphoglycerate Dehydrogenase; Proteomics; RNA-Seq; Serine; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2020 |
TGF-β Promotes Metabolic Reprogramming in Lung Fibroblasts via mTORC1-dependent ATF4 Activation.
Topics: Activating Transcription Factor 4; Collagen; Fibroblasts; Glycine; Glycolysis; Humans; Lung; Mechanistic Target of Rapamycin Complex 1; Mitochondria; Oxygen Consumption; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Stress, Physiological; TOR Serine-Threonine Kinases; Transforming Growth Factor beta | 2020 |
Photoprotection by mitochondrial alternative pathway is enhanced at heat but disabled at chilling.
Topics: Arabidopsis; Chlorophyll A; Cold Temperature; Glycine; Hot Temperature; Light; Methacrylates; Mitochondria; Mitochondrial Proteins; Mutation; NADP; Oxidoreductases; Photosynthesis; Plant Leaves; Plant Proteins; Serine; Thiazoles | 2020 |
Systemic lipid dysregulation is a risk factor for macular neurodegenerative disease.
Topics: Aged; Carbamoyl-Phosphate Synthase (Ammonia); Case-Control Studies; Diabetes Mellitus, Type 2; Female; Genetic Variation; Glycine; Humans; Male; Metabolic Networks and Pathways; Metabolome; Metabolomics; Middle Aged; Phosphatidylethanolamines; Phosphoglycerate Dehydrogenase; Phosphoric Monoester Hydrolases; Retinal Diseases; Risk Factors; Serine; Sphingomyelins | 2020 |
Characterization of XtjR8: A novel esterase with phthalate-hydrolyzing activity from a metagenomic library of lotus pond sludge.
Topics: Biodegradation, Environmental; Carboxylic Ester Hydrolases; Catalysis; Cloning, Molecular; Detergents; Dibutyl Phthalate; Esterases; Esters; Gene Library; Genomics; Glycine; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrolysis; Industry; Leucine; Lotus; Metagenome; Metagenomics; Molecular Conformation; Molecular Docking Simulation; Mutagenesis, Site-Directed; Organic Chemicals; Oxygen; Phthalic Acids; Ponds; Serine; Sewage; Solvents; Streptomyces; Temperature | 2020 |
Serine restriction alters sphingolipid diversity to constrain tumour growth.
Topics: Alanine; Animals; Cell Adhesion; Cell Division; Diet; Female; Glycine; HCT116 Cells; Humans; Membrane Lipids; Mice; Mitochondria; Neoplasms; Phosphoglycerate Dehydrogenase; Pyruvic Acid; Serine; Serine C-Palmitoyltransferase; Spheroids, Cellular; Sphingolipids; Stress, Physiological; Xenograft Model Antitumor Assays | 2020 |
A novel phosphoglycerol serine-glycine lipodipeptide of
Topics: Animals; Glycine; Humans; Ligands; Lipopeptides; Mice; Porphyromonas gingivalis; Serine; Toll-Like Receptor 2 | 2020 |
Transcriptional Activation of
Topics: Activating Transcription Factor 4; Animals; Biological Availability; Carcinoma, Hepatocellular; Cell Line, Tumor; gamma-Glutamylcyclotransferase; Gene Expression Regulation, Neoplastic; Glycine; Hydroxymethyl and Formyl Transferases; Liver Neoplasms; Mice; Phosphoglycerate Dehydrogenase; Serine; Transcriptional Activation; Up-Regulation | 2020 |
Extracellular serine and glycine are required for mouse and human skeletal muscle stem and progenitor cell function.
Topics: Adult; Aged; Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Female; Glycine; Humans; Male; Mice; Mice, Inbred C57BL; Muscle Development; Muscle, Skeletal; Myoblasts; Primary Cell Culture; Regeneration; Serine; Stem Cells | 2021 |
Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer.
Topics: Adenocarcinoma; Aged; Animals; Axons; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Codon; Female; Glycine; Humans; Male; Mice; Middle Aged; Mitochondria; Nerve Tissue; Neurons; Oxygen Consumption; Pancreatic Neoplasms; Protein Biosynthesis; Pyrazoles; Pyrimidines; Rats; RNA, Messenger; RNA, Transfer; Serine | 2020 |
Repurposing the Antidepressant Sertraline as SHMT Inhibitor to Suppress Serine/Glycine Synthesis-Addicted Breast Tumor Growth.
Topics: Animals; Antidepressive Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Repositioning; Female; Glycine; Glycine Hydroxymethyltransferase; Humans; Mice, Inbred NOD; Mice, SCID; Molecular Docking Simulation; Phosphoglycerate Dehydrogenase; Serine; Sertraline; Thimerosal | 2021 |
Tracing Metabolic Fate of Mitochondrial Glycine Cleavage System Derived Formate In Vitro and In Vivo.
Topics: Amino Acid Oxidoreductases; Animals; Cell Line; Female; Formates; Glycine; Humans; Mice; Mice, Inbred C57BL; Mitochondria; Multienzyme Complexes; Serine; Transferases | 2020 |
Astrocyte deletion of α2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathway.
Topics: Animals; Astrocytes; Ataxia; Brain; Disease Models, Animal; Electroencephalography; Female; Functional Neuroimaging; Glycine; Male; Metabolome; Mice; Mice, Knockout; Migraine with Aura; Rotarod Performance Test; Serine; Sodium-Potassium-Exchanging ATPase; Transcriptome | 2020 |
Inhibiting phosphoglycerate dehydrogenase counteracts chemotherapeutic efficacy against MYCN-amplified neuroblastoma.
Topics: Animals; Cell Line, Tumor; Female; Gene Amplification; Glycine; Humans; Mice; N-Myc Proto-Oncogene Protein; Neuroblastoma; Phosphoglycerate Dehydrogenase; Serine | 2021 |
A cross-platform approach identifies genetic regulators of human metabolism and health.
Topics: Diabetes Mellitus, Type 2; Eye Diseases; Gene Frequency; Genetic Loci; Genetic Pleiotropy; Genome, Human; Glucagon-Like Peptide-2 Receptor; Glycine; Health; Humans; Linear Models; Mendelian Randomization Analysis; Metabolism; Metabolism, Inborn Errors; Metabolome; Mutation, Missense; Phenotype; Polymorphism, Single Nucleotide; Retinal Telangiectasis; Sample Size; Serine | 2021 |
Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy.
Topics: Activating Transcription Factor 4; Animals; Cell Line, Tumor; Cell Proliferation; Female; Glycine; Humans; Male; Mice; Mice, Inbred C57BL; Neoplasms; Phosphoglycerate Dehydrogenase; Serine | 2021 |
Glioma cells require one-carbon metabolism to survive glutamine starvation.
Topics: Aminohydrolases; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; Glutamine; Glycine; Humans; Magnetic Resonance Spectroscopy; Metabolomics; Methylenetetrahydrofolate Dehydrogenase (NADP); Multifunctional Enzymes; Serine; Tumor Microenvironment; Up-Regulation | 2021 |
Impact of immune checkpoint gene CD155 Ala67Thr and CD226 Gly307Ser polymorphisms on small cell lung cancer clinical outcome.
Topics: Aged; Alanine; Amino Acid Substitution; Antigens, Differentiation, T-Lymphocyte; Carcinoma, Small Cell; Female; Glycine; Humans; Lung Neoplasms; Male; Polymorphism, Genetic; Receptors, Virus; Serine; Threonine; Treatment Outcome | 2021 |
Phosphatase of regenerating liver-3 regulates cancer cell metabolism in multiple myeloma.
Topics: Adenosine Triphosphate; Cell Line, Tumor; Cell Proliferation; Glycine; Glycine Dehydrogenase (Decarboxylating); Glycolysis; Humans; Multiple Myeloma; Neoplasm Proteins; Protein Tyrosine Phosphatases; Serine | 2021 |
Cystathionine-gamma-lyase overexpression in T cells enhances antitumor effect independently of cysteine autonomy.
Topics: Adoptive Transfer; Animals; CD8-Positive T-Lymphocytes; Cell Engineering; Cell Line, Tumor; Cell Proliferation; Cystathionine gamma-Lyase; Cysteine; Extracellular Fluid; Female; Glycine; Methionine; Mice; Mice, Inbred C57BL; Models, Animal; Ovarian Neoplasms; Proline; Serine; Tumor Microenvironment | 2021 |
Metabolic alterations in meningioma reflect the clinical course.
Topics: Aged; Algorithms; Biomarkers, Tumor; Choline; Cluster Analysis; Disease Progression; Female; Glycine; Humans; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Neoplasm Grading; Nuclear Magnetic Resonance, Biomolecular; Progression-Free Survival; Serine; Treatment Outcome; Tryptophan | 2021 |
Analgesic Activity of Jin Ling Zi Powder and Its Single Herbs: A Serum Metabonomics Study.
Topics: Analgesics; Animals; Aspirin; Biomarkers; Body Weight; Drugs, Chinese Herbal; Glycine; Glyoxylates; Inositol Phosphates; Isoleucine; Leucine; Metabolomics; Mice; Powders; RNA, Transfer; Serine; Threonine; Valine | 2022 |
The role of energy, serine, glycine, and 1-carbon units in the cost of nitrogen excretion in mammals and birds.
Topics: Animal Feed; Animals; Carbon; Chickens; Diet; Glycine; Mammals; Nitrogen; Serine | 2021 |
Prospective analysis of circulating metabolites and endometrial cancer risk.
Topics: Aged; Biomarkers, Tumor; Body Mass Index; Carnitine; Case-Control Studies; Endometrial Neoplasms; Female; Glycine; Humans; Metabolomics; Middle Aged; Prospective Studies; Risk Factors; Serine; Sphingomyelins | 2021 |
Alternative splicing of GluN1 gates glycine site-dependent nonionotropic signaling by NMDAR receptors.
Topics: Adaptor Protein Complex 2; Alternative Splicing; Animals; CA1 Region, Hippocampal; Dynamins; Endocytosis; Glycine; Interneurons; Ion Channel Gating; Mice; Nerve Tissue Proteins; Pyramidal Cells; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Serine; Signal Transduction; Synapses | 2021 |
Purification and characterization of an amyloidogenic repeat domain from the functional amyloid Pmel17.
Topics: Amino Acid Sequence; Amyloid; Endopeptidases; Fluorescent Dyes; Glycine; gp100 Melanoma Antigen; Histidine; Humans; Hydrogen-Ion Concentration; Melanosomes; Protein Aggregates; Serine; Tandem Mass Spectrometry | 2021 |
Glycine and serine markedly eliminate methylglyoxal in the presence of formaldehyde via the formation of imidazole salts.
Topics: Formaldehyde; Glycine; Imidazoles; Pyruvaldehyde; Salts; Serine | 2022 |
Glycine-Serine-Threonine Metabolic Axis Delays Intervertebral Disc Degeneration through Antioxidant Effects: An Imaging and Metabonomics Study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antioxidants; Diffusion Tensor Imaging; Glycine; Humans; Intervertebral Disc Degeneration; Metabolomics; Middle Aged; Rats; Rats, Sprague-Dawley; Serine; Young Adult | 2021 |
Oncogenic Ras expression increases cellular formate production.
Topics: Aminohydrolases; Animals; Formate-Tetrahydrofolate Ligase; Formates; Gene Expression Regulation; Genes, ras; Glycine; Glycine Hydroxymethyltransferase; Methenyltetrahydrofolate Cyclohydrolase; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Multienzyme Complexes; Multifunctional Enzymes; NIH 3T3 Cells; ras Proteins; RNA, Messenger; Serine | 2021 |
The impact of physiological metabolite levels on serine uptake, synthesis and utilization in cancer cells.
Topics: Biosynthetic Pathways; Cell Line, Tumor; Cell Proliferation; Culture Media; Glycine; Humans; Hypoxanthine; Neoplasms; Purines; Serine; Up-Regulation | 2021 |
Relationship between indirect genetic effects for growth, environmental enrichment, coping style and sex with the serum metabolome profile of pigs.
Topics: Adaptation, Psychological; Animals; Female; Glycine; Housing, Animal; Magnetic Resonance Spectroscopy; Male; Metabolomics; Orchiectomy; Selective Breeding; Serine; Swine; Threonine | 2021 |
Metabolomics and microbiomes for discovering biomarkers of antituberculosis drugs-induced hepatotoxicity.
Topics: Adult; Antitubercular Agents; Biomarkers; Chemical and Drug Induced Liver Injury; Female; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Male; Metabolomics; Microbiota; Middle Aged; RNA, Ribosomal, 16S; Serine; Threonine | 2022 |
Plasma Metabolomic Changes in Children with Cerebral Palsy Exposed to Botulinum Neurotoxin.
Topics: Botulinum Toxins, Type A; Cerebral Palsy; Child; Cysteine; Glycine; Humans; Injections, Intramuscular; Methionine; Muscle Spasticity; Neuromuscular Agents; Serine; Threonine; Treatment Outcome | 2022 |
Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression.
Topics: Amino Acid Substitution; Amyloid beta-Protein Precursor; Carrier Proteins; Cell Differentiation; Cytokines; Embryo, Mammalian; GATA3 Transcription Factor; Gene Expression Regulation, Developmental; Glycine; HSP40 Heat-Shock Proteins; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mesencephalon; Models, Biological; Mutation; Neurogenesis; Organoids; Parkinson Disease; Sequence Analysis, RNA; Serine; Single-Cell Analysis; Transcriptome | 2022 |
The role of SHMT2 in modulating lipid metabolism in hepatocytes via glycine-mediated mTOR activation.
Topics: Animals; Glycine; Glycine Hydroxymethyltransferase; Hepatocytes; Hydroxymethyl and Formyl Transferases; Lipid Metabolism; Lipids; Mice; PPAR gamma; Serine; TOR Serine-Threonine Kinases | 2022 |
Comprehensively understanding metabolic pathways of protein during the anaerobic digestion of waste activated sludge.
Topics: Acetyl Coenzyme A; Alanine; Amino Acids; Anaerobiosis; Arginine; Glutamates; Glycine; Histidine; Leucine; Lysine; Metabolic Networks and Pathways; Methionine; Phenylalanine; Pyruvic Acid; Serine; Sewage; Threonine; Tyrosine | 2022 |
Gut microbiome-derived glycine lipids are diet-dependent modulators of hepatic injury and atherosclerosis.
Topics: Animals; Atherosclerosis; Bacteria; Bacteroidetes; Diet, High-Fat; Gastrointestinal Microbiome; Glycine; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Serine | 2022 |
Proteomic analysis reveals the heterogeneity of metabolic reprogramming in lacrimal gland tumors.
Topics: Chromatography, Liquid; Eye Neoplasms; Glycine; Humans; Lacrimal Apparatus; Lacrimal Apparatus Diseases; Proteomics; Serine; Tandem Mass Spectrometry; Threonine | 2022 |
Cerebrospinal fluid amino acids glycine, serine, and threonine in nonketotic hyperglycinemia.
Topics: Amino Acids; Cross-Sectional Studies; Glycine; Humans; Hyperglycinemia, Nonketotic; Infant, Newborn; Serine; Threonine | 2022 |
Metabolomics study of the effect of Danggui Buxue Tang on rats with chronic fatigue syndrome.
Topics: Angelica sinensis; Animals; Drugs, Chinese Herbal; Fatigue Syndrome, Chronic; Glycine; Metabolomics; Rats; Serine; Threonine; Tyrosine | 2022 |
Impact of heat stress on milk yield, antioxidative levels, and serum metabolites in primiparous and multiparous Holstein cows.
Topics: Animals; Antioxidants; Cattle; Cattle Diseases; Female; Glycine; Heat Stress Disorders; Heat-Shock Response; Lactation; Milk; Parity; Pregnancy; Serine | 2022 |
Genetic variants in ALDH1L1 and GLDC influence the serine-to-glycine ratio in Hispanic children.
Topics: Child; Genome-Wide Association Study; Glycine; Glycine Dehydrogenase (Decarboxylating); Hispanic or Latino; Humans; Insulin Resistance; Oxidoreductases Acting on CH-NH Group Donors; Serine | 2022 |
GC-MS based metabolite fingerprinting of serous ovarian carcinoma and benign ovarian tumor.
Topics: Benzoic Acid; Biomarkers; Creatinine; Female; Gas Chromatography-Mass Spectrometry; Glutathione; Glycine; Humans; Metabolomics; Ovarian Neoplasms; Pyrrolidonecarboxylic Acid; RNA, Transfer; Serine; Threonine | 2022 |
New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming.
Topics: Animals; Arachnodactyly; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinogenesis; Cholangiocarcinoma; Contracture; Epigenesis, Genetic; ErbB Receptors; Glucose; Glycine; Humans; Interleukin-6; Mice; Phosphoglycerate Dehydrogenase; Proteomics; Proto-Oncogene Proteins p21(ras); Rats; Serine | 2022 |
Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy.
Topics: Activating Transcription Factor 4; Adenosine Triphosphate; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cardiomyopathy, Dilated; Drug Evaluation, Preclinical; Glucose; Glycine; Humans; Imidazoles; Induced Pluripotent Stem Cells; Molecular Targeted Therapy; Mutation; Myocytes, Cardiac; Phosphoglycerate Dehydrogenase; Protein Kinase Inhibitors; Pyridines; Serine; Troponin T | 2022 |
SHMT2 promotes the tumorigenesis of renal cell carcinoma by regulating the m6A modification of PPAT.
Topics: Amidophosphoribosyltransferase; Carbon; Carcinogenesis; Carcinoma, Renal Cell; Cell Proliferation; Cell Transformation, Neoplastic; Glycine; Glycine Hydroxymethyltransferase; Humans; Kidney Neoplasms; RNA-Binding Proteins; Serine | 2022 |
Glycine-serine-rich effector PstGSRE4 in Puccinia striiformis f. sp. tritici inhibits the activity of copper zinc superoxide dismutase to modulate immunity in wheat.
Topics: Basidiomycota; Copper; Glycine; Hydrogen Peroxide; Plant Diseases; Puccinia; Serine; Superoxide Dismutase; Triticum; Zinc | 2022 |
Amino Acids Compete with Ammonia in Sulfuric Acid-Based Atmospheric Aerosol Prenucleation: The Case of Glycine and Serine.
Topics: Aerosols; Amino Acids; Ammonia; Glycine; Serine; Sulfuric Acids; Thermodynamics | 2022 |
A new perspective on endocrine disrupting effects of triphenyltin on marine medaka: From brain transcriptome, gut content metabolome and behavior.
Topics: Animals; Brain; Glycine; Humans; Metabolome; Organotin Compounds; Oryzias; PPAR gamma; Serine; Threonine; Transcriptome; Water Pollutants, Chemical | 2022 |
Yogurt Benefits Bone Mineralization in Ovariectomized Rats with Concomitant Modulation of the Gut Microbiome.
Topics: Animals; Calcification, Physiologic; Calcium; Calcium Carbonate; Calcium, Dietary; Fatty Acids, Volatile; Female; Gastrointestinal Microbiome; Glycine; Inulin; Rats; Serine; Threonine; Yogurt | 2022 |
Chemical shift assignments of a fusion protein comprising the C-terminal-deleted hepatitis B virus X protein BH3-like motif peptide and Bcl-x
Topics: Apoptosis Regulatory Proteins; bcl-X Protein; Carcinoma, Hepatocellular; Dipeptides; Glycine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Neoplasms; Nuclear Magnetic Resonance, Biomolecular; Serine; Trans-Activators; Viral Regulatory and Accessory Proteins | 2022 |
Tetramate Derivatives by Chemoselective Dieckmann Ring Closure of
Topics: Anti-Bacterial Agents; Benzaldehydes; Glycine; Microbial Sensitivity Tests; Serine | 2022 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
Network pharmacology combined with metabolomics reveals the mechanism of Fuzi decoction against chronic heart failure in rats.
Topics: Animals; beta-Alanine; Chronic Disease; Coenzyme A; Diterpenes; Drugs, Chinese Herbal; Glycine; Glyoxylates; Heart Failure; Lactates; Metabolomics; Network Pharmacology; Pyruvates; Rats; RNA, Transfer; Serine; Threonine | 2022 |
The combination of microbiome and metabolome to analyze the cross-cooperation mechanism of
Topics: Alanine; Animals; Echinacea; Fatty Acids, Volatile; Gastrointestinal Microbiome; Glycine; Glycosphingolipids; Humans; Leucine; Metabolome; Mice; Microbiota; Ornithine; Phenylalanine; Polysaccharides; Porphyrins; Serine; Threonine; Tryptophan; Tyrosine | 2022 |
Recent strains of influenza D virus create a new genetic cluster for European strains.
Topics: Alanine; Animals; Arginine; Asparagine; Aspartic Acid; Cattle; Cattle Diseases; Glycine; Nucleotides; Orthomyxoviridae; Orthomyxoviridae Infections; Phylogeny; Proline; Serine; Thogotovirus; Threonine; Valine | 2022 |
Sensitisation of cancer cells to radiotherapy by serine and glycine starvation.
Topics: Amino Acids; Animals; Antioxidants; Glycine; Mice; Pancreatic Neoplasms; Serine | 2022 |
Transcriptomic and proteomic analysis of Staphylococcus aureus response to cuminaldehyde stress.
Topics: Adenosine Triphosphate; Amino Acids, Branched-Chain; Animals; Anti-Bacterial Agents; Bacterial Proteins; Benzaldehydes; Betaine; Cattle; Cymenes; Cysteine; DNA, Single-Stranded; Fatty Acids; Gene Expression Regulation, Bacterial; Glycine; Iron; Methionine; Peptidoglycan; Proteomics; Serine; Staphylococcal Infections; Staphylococcus aureus; Threonine; Transcriptome | 2022 |
Characterization of a new Bacillus velezensis as a powerful biocontrol agent against tomato gray mold.
Topics: Agar; Antifungal Agents; Antioxidants; Bacillus; Catalase; Cellulose; Complex Mixtures; Glucose; Glycine; Peptide Hydrolases; Phosphoric Monoester Hydrolases; Plant Diseases; Salicylic Acid; Serine; Siderophores; Solanum lycopersicum; Sulfur; Superoxide Dismutase; Threonine | 2022 |
Functional and Structural Characterization of OXA-935, a Novel OXA-10-Family β-Lactamase from Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Aspartic Acid; Azabicyclo Compounds; beta-Lactamase Inhibitors; beta-Lactamases; Ceftazidime; Cephalosporinase; Cephalosporins; Glycine; Humans; Microbial Sensitivity Tests; Phenylalanine; Pseudomonas aeruginosa; Pseudomonas Infections; Serine; Tazobactam | 2022 |
Modulating Nanodroplet Formation En Route to Fibrillization of Amyloid Peptides with Designed Flanking Sequences.
Topics: Amyloid; Amyloid beta-Peptides; Amyloidosis; Glycine; Humans; Nanostructures; Serine | 2022 |
NMR-Based Metabolomic Analysis of Cardiac Tissues Clarifies Molecular Mechanisms of CVB3-Induced Viral Myocarditis and Dilated Cardiomyopathy.
Topics: Alanine; Animals; Aspartic Acid; Biomarkers; Cardiomyopathy, Dilated; Coxsackievirus Infections; Enterovirus B, Human; Glutamic Acid; Glutamine; Glycine; Mice; Mice, Inbred BALB C; Myocarditis; Niacin; Niacinamide; Serine; Taurine; Threonine | 2022 |
[Determination of free amino acids in Eriocheir sinensis by ultra-high performance liquid chromatography-high resolution mass spectrometry].
Topics: Acetonitriles; Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brachyura; Chromatography, High Pressure Liquid; Cystine; Formates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Mass Spectrometry; Methionine; Perchlorates; Phenylalanine; Polypropylenes; Proline; Serine; Solvents; Threonine; Tyrosine; Valine; Water | 2022 |
Proteomic, Transcriptomic, Mutational, and Functional Assays Reveal the Involvement of Both THF and PLP Sites at the GmSHMT08 in Resistance to Soybean Cyst Nematode.
Topics: Animals; Carbon; Cysts; Glycine; Glycine Hydroxymethyltransferase; Glycine max; Glyoxylates; Heme; Methionine; Nematoda; Plant Diseases; Proteomics; Purines; Pyridoxal Phosphate; Serine; Tetrahydrofolates; Transcriptome | 2022 |
Cardioprotective Mechanism of Leonurine against Myocardial Ischemia through a Liver-Cardiac Crosstalk Metabolomics Study.
Topics: Amino Acids; Animals; Coronary Artery Disease; Fatty Acids; Glycine; Liver; Metabolomics; Myocardial Ischemia; Purines; Rats; Rats, Sprague-Dawley; Serine; Threonine | 2022 |
Prolonged Febrile Seizures Impair Synaptic Plasticity and Alter Developmental Pattern of Glial Fibrillary Acidic Protein (GFAP)-Immunoreactive Astrocytes in the Hippocampus of Young Rats.
Topics: Animals; Astrocytes; Epilepsy; Glial Fibrillary Acidic Protein; Glycine; Hippocampus; Neuronal Plasticity; Rats; Receptors, N-Methyl-D-Aspartate; Seizures, Febrile; Serine; Status Epilepticus | 2022 |
Benincasa hispida extracts positively regulated high salt-induced hypertension in Dahl salt-sensitive rats: Impact on biochemical profile and metabolic patterns.
Topics: Alanine; Amino Acids; Animals; Antihypertensive Agents; Antioxidants; Aspartic Acid; Cucurbitaceae; Glycine; Hypertension; Phenylalanine; Plant Extracts; Rats; Rats, Inbred Dahl; Renal Insufficiency; Serine; Sodium Chloride; Sodium Chloride, Dietary; Threonine; Tyrosine | 2022 |
The ovine conceptus utilizes extracellular serine, glucose, and fructose to generate formate via the one carbon metabolism pathway.
Topics: Animals; Female; Formates; Fructose; Glucose; Glycine; Interferon Type I; Male; Pregnancy; Serine; Sheep; Sheep, Domestic | 2023 |
Changes in sugar, organic acid and free amino acid levels and the expression of genes involved in the primary metabolism of oleocellosis in citrus peels.
Topics: Amino Acids; Citrus; Citrus sinensis; Fruit; Gene Expression Regulation, Plant; Glycine; Serine; Sugars | 2023 |
Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms.
Topics: Animals; Cell Proliferation; Glycine; Glycine Hydroxymethyltransferase; Humans; Inflammation; Mice; Psoriasis; Serine; Skin Diseases | 2022 |
Integrated flux and pool size analysis in plant central metabolism reveals unique roles of glycine and serine during photorespiration.
Topics: Carbon; Carbon Dioxide; Glycine; Nitrogen; Photosynthesis; Plants; Serine | 2023 |
Metabolic pathway analysis of hyperuricaemia patients with hyperlipidaemia based on high-throughput mass spectrometry: a case‒control study.
Topics: Alanine; Aspartic Acid; Biomarkers; Case-Control Studies; Glycine; Humans; Hyperlipidemias; Hyperuricemia; Linoleic Acid; Mass Spectrometry; Metabolic Diseases; Metabolic Networks and Pathways; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine | 2022 |
Nutritional geometry framework of sleep.
Topics: Animals; Diet; Diet, Protein-Restricted; Dietary Carbohydrates; Dietary Proteins; Drosophila; Female; Glucose; Glycine; Glycogen; Male; Serine; Sleep; Threonine | 2023 |
Toward Accurate yet Effective Computations of Rotational Spectroscopy Parameters for Biomolecule Building Blocks.
Topics: Glycine; Serine; Spectrum Analysis | 2023 |
Insulin-regulated serine and lipid metabolism drive peripheral neuropathy.
Topics: Adiposity; Animals; Diabetes Mellitus, Experimental; Diet, High-Fat; Dyslipidemias; Glycine; Insulin; Lipid Metabolism; Mice; Peripheral Nervous System Diseases; Serine; Small Fiber Neuropathy; Sphingolipids | 2023 |
[Intervention study to inhibit the glucose metabolic remodeling in hepatocytes induced by high-selenium in vitro].
Topics: Glutathione Peroxidase GPX1; Glycine; Hepatocytes; Selenium; Serine | 2023 |
Metabolic Mechanism of
Topics: Bacillus; Glycine; Metabolomics; Serine; Threonine | 2023 |
Metabolomics profiling of seminal plasma in obesity-induced asthenozoospermia.
Topics: Aconitic Acid; Alanine; Asthenozoospermia; Citrulline; Glucose; Glutamic Acid; Glycine; Humans; Leucine; Lysine; Male; Metabolomics; Phenylalanine; Proline; Semen; Serine; Succinic Acid; Threonine; Tyrosine; Valine | 2023 |
Metabolic perturbations in pregnant rats exposed to low-dose perfluorooctanesulfonic acid: An integrated multi-omics analysis.
Topics: Animals; Female; Fluorocarbons; Glycine; Multiomics; Pregnancy; Rats; Rats, Sprague-Dawley; Serine; Steroids; Threonine | 2023 |
Loss of peroxisomal NAD kinase 3 (NADK3) affects photorespiration metabolism in Arabidopsis.
Topics: Arabidopsis; Carbon Dioxide; Glycine; NAD; NADP; Serine | 2023 |
Transcription factor NKX2-1 drives serine and glycine synthesis addiction in cancer.
Topics: Animals; Cell Line; Cell Line, Tumor; Glycine; Humans; Lung Neoplasms; Mice; Serine; Thyroid Nuclear Factor 1; Transcription Factors | 2023 |
Divergent amino acid and sphingolipid metabolism in patients with inherited neuro-retinal disease.
Topics: Alanine; Amino Acids; Animals; Glycine; Hereditary Sensory and Autonomic Neuropathies; Mice; Retinal Diseases; Serine; Sphingolipids; Sphingomyelins | 2023 |
Dietary protein reduction with stepwise addition of crystalline amino acids and the effect of considering a minimum glycine-serine content in broiler diets.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Dietary Proteins; Dietary Supplements; Glycine; Glycine max; Male; Serine | 2023 |
Adaptive responses in uteroplacental metabolism and fetoplacental nutrient shuttling and sensing during placental insufficiency.
Topics: Amino Acids; AMP-Activated Protein Kinases; Animals; Female; Fetal Growth Retardation; Fetus; Glucose; Glutamine; Glycine; Humans; Lactic Acid; Nutrients; Oxygen; Placenta; Placental Insufficiency; Pregnancy; Pyruvates; Serine; Sheep | 2023 |
Serine metabolism during differentiation of human iPSC-derived astrocytes.
Topics: Astrocytes; Cell Differentiation; Glycine; Humans; Induced Pluripotent Stem Cells; Proteomics; Receptors, N-Methyl-D-Aspartate; Serine | 2023 |
Efficient production of natural sunscreens shinorine, porphyra-334, and mycosporine-2-glycine in Saccharomyces cerevisiae.
Topics: Amino Acids; Cyanobacteria; Glycine; Saccharomyces cerevisiae; Serine; Sunscreening Agents; Threonine | 2023 |
Beyond photorespiration: the significance of glycine and serine in leaf metabolism.
Topics: Carbon Dioxide; Cell Respiration; Glycine; Photosynthesis; Plant Leaves; Serine | 2023 |
The Role of Serine-Glyoxylate Aminotransferase and Malyl-CoA Lyase in the Metabolism of Methylococcus capsulatus Bath.
Topics: Glycine; Leucine; Methylococcus capsulatus; Serine | 2023 |
Transcriptomics integrated with metabolomics reveals perfluorobutane sulfonate (PFBS) exposure effect during pregnancy and lactation on lipid metabolism in rat offspring.
Topics: Alanine; Animals; Aspartic Acid; Cytochrome P-450 Enzyme System; Female; Gene Expression Profiling; Glycine; Lactation; Lipid Metabolism; Metabolomics; Pantetheine; Phosphates; Pregnancy; Rats; Serine; Threonine; Transcriptome; Xenobiotics | 2023 |
Mutant p53 sustains serine-glycine synthesis and essential amino acids intake promoting breast cancer growth.
Topics: Amino Acids; Amino Acids, Essential; Breast Neoplasms; Female; Glycine; Humans; Large Neutral Amino Acid-Transporter 1; Serine; Tumor Suppressor Protein p53 | 2023 |
Detection and identification of amino acids and proteins using their intrinsic fluorescence in the visible light spectrum.
Topics: Alanine; Amino Acids; Arginine; Cystine; Fluorescence; Glycine; Leucine; Methionine; Proteins; Serine; Threonine; Tyrosine; Valine | 2023 |
Metabolic alterations unravel the maternofetal immune responses with disease severity in pregnant women infected with SARS-CoV-2.
Topics: COVID-19; Cytokines; Female; Glycine; Humans; Immunity; Infant, Newborn; Interferon-alpha; Interleukin-6; Interleukin-9; Lactates; NAD; Patient Acuity; Pregnancy; Pregnant Women; Pyruvates; Riboflavin; SARS-CoV-2; Serine; Threonine | 2023 |