serine has been researched along with glutamic acid in 599 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 39 (6.51) | 18.7374 |
| 1990's | 145 (24.21) | 18.2507 |
| 2000's | 260 (43.41) | 29.6817 |
| 2010's | 118 (19.70) | 24.3611 |
| 2020's | 37 (6.18) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Kinoshita, H; Shimizu, K | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Boudker, O; Gouaux, E; Ryan, RM; Shimamoto, K; Yernool, D | 1 |
| Bonini, BM; Thevelein, JM; Van Zeebroeck, G; Versele, M | 1 |
| Brzović, PS; Dunn, MF; Kayastha, AM; Miles, EW | 1 |
| Countaway, JL; Davis, RJ; Nair, N; Robinson, HL; Taglienti-Sian, C; Theroux, SJ | 1 |
| O'Keefe, DO | 1 |
| Abarca, J; Bradberry, CW; Bustos, G; Forray, MI; Gysling, K; Roth, RH | 1 |
| Hirano, H; Kawamura, M; Kuboki, Y; Mizuno, M; Yamada, H; Zhou, HY | 1 |
| Kus, L; McNulty, JA; Ottersen, OP | 1 |
| Jankásková, B; Lisý, V; Stastný, F | 1 |
| Berg, M; Bruhn, T; Cobo, M; Diemer, NH | 1 |
| Bowne, DB; Flores, E; Matthews, RJ; Thomas, ML | 1 |
| Ellingsen, JE; Rykke, M; Sönju, T | 1 |
| Dantzler, WH; Silbernagl, S | 1 |
| Beart, PM; Conway, EL; Manallack, DT; Mercer, LD; O'Shea, RD | 1 |
| Rykke, M; Sönju, T | 1 |
| Aletras, AJ; Hjerpe, A; Karamanos, NK | 1 |
| Collen, D; Lijnen, HR; Nelles, L; Van Hoef, B | 1 |
| Gunawan, S; Treiman, DM; Walton, NY | 1 |
| da Fonseca-Wollheim, F | 1 |
| Brosnan, JT; Brosnan, ME; Dhanakoti, SN; Herzberg, GR | 1 |
| Hamano, S; Morita, K; Oka, M; Teraoka, K | 1 |
| Sotiroudis, TG; Xenakis, A | 1 |
| Collier, RJ; Reich, KA; Weinstein, BR; Wilson, BA | 1 |
| Chang, YS; Papkoff, H | 1 |
| Daly, MP; Demediuk, P; Faden, AI | 1 |
| Gerlt, JA; Hibler, DW; Mildvan, AS; Serpersu, EH | 1 |
| de Vrij, W; Konings, WN; Speelmans, G | 1 |
| Bertranpetit, J; Marín, A; Medina, JR; Oliver, JL | 1 |
| Christoph, G; Siman, R | 1 |
| Ahl, PL; Khorana, HG; Mogi, T; Rothschild, KJ; Stern, LJ | 1 |
| Askanazi, J; Elwyn, DH; Gil, KM; Gump, FE; Kinney, JM; Starker, PM | 1 |
| Cohen, AS; Connors, LH; Gertz, MA; Kyle, RA; Skinner, M | 1 |
| Davis, EJ; Scaduto, RC | 1 |
| Druse, MJ; Rathbun, WE | 1 |
| Coyle, JT; Koller, KJ | 1 |
| Nakamura, Y; Nakaya, K; Shibayama, T | 1 |
| Allen, IC; Grieve, A; Griffiths, R | 1 |
| Mora, F; Peinado, JM | 1 |
| Rechsteiner, M; Rogers, S; Wells, R | 1 |
| Arrieta, A; Bonilla, E; Prasad, AL | 1 |
| Booth, CL; Howell, EE; Kraut, J; Villafranca, JE; Warren, MS | 1 |
| Cain, BD; Chun, KT; Simoni, RD; Vik, SB | 1 |
| Horecker, BL; Panneerselvam, C; Wellner, D | 1 |
| Meggio, F; Pinna, LA | 1 |
| Jankásková, B; Lisý, V; Murphy, S; Pearce, B; Stastný, F | 1 |
| Craik, CS; Gráf, L; Hegyi, G; Hepp, J; Likó, I; Medzihradszky, K; Rutter, WJ | 1 |
| Rechsteiner, M | 1 |
| Karunasagar, I | 1 |
| Lal, DN; Srivastava, AS | 1 |
| Beezer, AE; Chowdhry, BZ; Cosgrove, RF; Sharma, PB | 1 |
| Hájková, B; Lisý, V; Murphy, S; Stastný, F | 1 |
| Männistö, PT; Mattila, J; Tuominen, RK; Vesalainen, S | 1 |
| Miller, RD; Morse, SA; Tesh, MJ | 1 |
| Bussolati, O; Dall'Asta, V; Franchi-Gazzola, R; Gazzola, GC; Guidotti, GG; Longo, N | 1 |
| de Moraes, GH; Featherston, WR; Rogler, JC | 1 |
| Bhatnagar, R; Chauhan, BS; Desai, NC; Garg, SP | 1 |
| Mora, F; Myers, RD; Peinado, JM | 1 |
| Davis, JP; Stephens, GC | 1 |
| Jahoor, F; Jaksic, T; Miller, RG | 1 |
| Anderson, PJ; Brooks, CL; Maciejewski, PM; Peterson, FC | 1 |
| Botscheller, ML; DeKosky, ST; Marion, DW; Palmer, AM; Styren, SD; Swedlow, PE | 1 |
| Eckardt, S; Köhr, G; Lüddens, H; Monyer, H; Seeburg, PH | 1 |
| Desiderio, S; Malek, SN | 1 |
| Joung, I; Kim, T; Payne, G; Shin, J; Stolz, LA; Strominger, JL; Walsh, CT; Winkler, DG | 1 |
| Gonzalez, J; Leslie, SW; Randall, PK; Spuhler-Phillips, K | 1 |
| Almahbobi, G; de Kretser, DM; Kim, YH; McFarlane, JR; Stanton, PG; Temple-Smith, PD | 1 |
| Hashimoto, A; Nishikawa, T; Oka, T | 1 |
| Bannai, S; Fujiwara, K; Sagara, J; Sato, H | 1 |
| Gully, NJ; Rogers, AH | 1 |
| Berendes, R; Burger, A; Demange, P; Huber, R; Voges, D | 1 |
| Bowie, D; Mayer, ML; Partin, KM | 1 |
| Molliver, ME; Schell, MJ; Snyder, SH | 1 |
| Bendahan, G; Boatell, ML; Mahy, N | 1 |
| Baglia, FA; Gurr, JA; Jameson, BA; Seaman, FS; Walsh, PN | 1 |
| Dimpfel, W | 1 |
| Bannai, S; Miura, K; Sagara, J | 1 |
| Hartshorne, DJ; Ikebe, M; Mitra, S | 1 |
| Castagné, V; Finot, PA; Maire, JC | 1 |
| Kumagai, N; Maruta, H; Morii, N; Narumiya, S; Nur-E-Kamal, MS | 1 |
| Citron, BA; Davis, MD; Kaufman, S | 1 |
| Brann, DW; Mahesh, VB; Ping, L; Wiedmeier, VT | 1 |
| Cowley, S; Kemp, P; Marshall, CJ; Paterson, H | 1 |
| Ahrens, F; Mosenthin, R; Sauer, WC | 1 |
| Choi, DW; Helfrich, LR; Kouchoukos, NT; Lobner, DC; Rokkas, CK | 1 |
| Inao, S; Kuchiwaki, H; Sugita, K; Yamamoto, M; Yoshida, K | 1 |
| Kotler, Y; Padan, E; Pinner, E; Schuldiner, S | 1 |
| Blackstone, CD; Huganir, RL; Raymond, LA | 1 |
| Curran, TP; Riordan, JF; Shapiro, R | 1 |
| Fedele, E; Foster, AC | 1 |
| Konings, WN; Poolman, B; Speelmans, G | 1 |
| Chevaillier, P | 1 |
| Hirai, H; Okada, Y | 1 |
| Anglés-Cano, E; Fleury, V; Lijnen, HR | 1 |
| Fisher, HF; Maniscalco, SJ; Saha, SK; Vicedomine, P | 1 |
| Barnes, JA; Gomes, AV | 1 |
| Anders, J; Mense, M; Schlegel, R; Sparkowski, J | 1 |
| Bollen, M; Gaussin, V; Hue, L; Stalmans, W | 1 |
| Frank, JS; Hryshko, LV; Matsuoka, S; Nicoll, DA; Philipson, KD | 1 |
| Li, Y; Ng, JP; Wolf, ME; Xue, CJ | 1 |
| Capaldi, RA; Grüber, G | 1 |
| Liddington, RC; Loftus, JC; Smeeton, AH; Sutcliffe, MJ; Tozer, EC | 1 |
| Angelini, GD; Birkett, S; Suleiman, MS; Wallace, D | 1 |
| Rechsteiner, M; Rogers, SW | 1 |
| Kaur, S; Mackenzie, B; Peter, GJ; Taylor, PM | 1 |
| Akabori, S; Muramatsu, I; Tamaki, M | 1 |
| Argast, GM; Eldar-Finkelman, H; Fischer, EH; Foord, O; Krebs, EG | 1 |
| Chalmers, JP; Kapoor, R; Kapoor, V | 1 |
| Izzarelli, DG; Lewis-Higgins, L; Palmer, D; Parker, EM; Shapiro, RA | 1 |
| Angkanaporn, K; Bryden, WL; Ravindran, V | 1 |
| Alcaraz, AF; Daniels, AH; Fujikawa, DG; Kim, JS; Sohn, TB | 1 |
| Carolan, VA; Gardner, ML; Lucy, D; Pollard, AM | 1 |
| Fabbri, E; Lucchi, R; Notari, S; Poli, A; Virgili, M | 1 |
| Lentz, MR; Saville, BM; Spacek, SM; Stanley, CM; Zanardi, TA | 1 |
| Miyazaki, K; Oshima, T; Yaoi, T | 1 |
| Berger, RE; Donnellan, JP; Doyle, JM; Escarciga, R; Mason, PA; Romano, WF | 1 |
| Carr, B; Deng, X; Ito, T; May, WS | 1 |
| Dirig, DM; Hua, XY; Yaksh, TL | 1 |
| Hanscombe, O; O'Hare, P; O'Reilly, D | 1 |
| Moitra, J; Szilák, L; Vinson, C | 1 |
| Browner, MF; Buchbinder, JL; Fletterick, RJ; Luong, CB | 1 |
| Edwards, AS; Newton, AC | 1 |
| Funahashi, Y; Hasegawa, J; Kamada, S; Kusano, H; Tsujimoto, Y; Washida, M | 1 |
| Belloni, E; Gaudenz, K; Muenke, M; Roessler, E; Scherer, SW; Tsui, LC; Vargas, F | 1 |
| Abildgaard, S; Jensen, G; Nordestgaard, BG; Steffensen, R; Tybjaerg-Hansen, A; Wittrup, HH | 1 |
| Aman, MJ; Henkart, PA; Leonard, WJ; Nakajima, H; Noguchi, M; Sarin, A; Shores, EW | 1 |
| Bruneau, N; Fisher, EA; Lombardo, D; Nganga, A | 1 |
| Becker, J; Block, C; Herrmann, C; Jaitner, BK; Linnemann, T; Wittinghofer, A | 1 |
| Aghajanian, S; Engel, PC; Goyal, A; Hayden, BM; Wang, XG | 1 |
| Galindo, RL; Liu, ZP; Wasserman, SA | 1 |
| Jordan, P; Karess, R | 1 |
| Darstein, M; Feuerstein, TJ; Knörle, R; Löschmann, PA | 1 |
| Battaglia, FC; Chung, M; Meschia, G; Teng, C; Timmerman, M | 1 |
| Kempski, OS; Kossmann, T; Lowitzsch, K; Morganti-Kossmann, MC; Pleines, UE; Stover, JF | 1 |
| Daggett, LP; Deal, C; Hess, SD; Johnson, EC; Lu, CC; Veliçelebi, G | 1 |
| Hunter, T; Potter, LR | 4 |
| Eisenberg, E; Greene, L; Rajapandi, T; Wu, C | 1 |
| Behr, J; Hellwig, P; Ludwig, B; Mäntele, W; Michel, H; Odenwald, A; Ostermeier, C; Pfitzner, U; Richter, OM | 1 |
| Gorski, JP | 1 |
| Amara, SG; Johnston, GA; Mitrovic, AD; Vandenberg, RJ | 1 |
| Burnett, JP; Clark, B; Cockerham, SL; Evans, N; Kingston, AE; Lodge, D; Lowndes, J; Mayne, NG; Tomlinson, R | 1 |
| Prüss, BM | 1 |
| Ivanovic, A; Kuhse, J; Laube, B; Reiländer, H | 1 |
| Gemignani, A; Paudice, P; Raiteri, M | 1 |
| Blodig, W; Doyle, WA; Piontek, K; Smith, AT; Veitch, NC | 1 |
| Ambert-Balay, K; Fuchs, SM; Tien, M | 1 |
| Semba, J | 1 |
| Arthur, JS; Croall, DE; Dutt, P; Elce, JS | 1 |
| Bosque-Hamilton, P; Huang, PL; Lo, EH; Moskowitz, MA; Shimizu-Sasamata, M | 1 |
| Davidson, AR; Maxwell, KL | 1 |
| Munagala, NR; Wang, CC | 1 |
| Burd, AL; El-Kouhen, R; Erickson, LJ; Law, PY; Loh, HH | 1 |
| Anderson, SA; Brown, NM; Carpenter, TB; Eisenstein, RS; Kennedy, MC; Steffen, DW; Walden, WE | 1 |
| Ascher, P; Berger, AJ; Dieudonné, S | 1 |
| Munck, BG; Munck, LK | 1 |
| Kempski, OS; Kossmann, T; Morganti-Kossmann, MC; Pleines, UE; Stocker, R; Stover, JF | 1 |
| Kanner, BI; Zhang, Y | 1 |
| Bowers, K; Fingerhut, A; Höning, S; Marsh, M; Pitcher, C | 1 |
| Gschwendt, M; Marks, F; Radke, S; Rincke, G; Schnölzer, M; Stempka, L | 1 |
| Overman, SA; Thomas, GJ | 1 |
| Carey, PR; Dong, J; Dunaway-Mariano, D; Luo, L; Xiang, H | 1 |
| Mizuno, K; Tanaka, T; Toshima, J | 1 |
| Elsliger, MA; Hanson, GT; Kallio, K; Remington, SJ; Wachter, RM | 1 |
| Hurley, TD; Weiner, H | 1 |
| Amin, A; Archambault, J; Brault, K; Cordingley, MG; Pelletier, A; Sauvé, F; Titolo, S; Wardrop, E; White, PW | 1 |
| Banerjee, AK; Das, T; Englund, N; Hwang, LN; Pattnaik, AK | 1 |
| Beachy, RN; Hosokawa, D; Kawakami, S; Okada, Y; Padgett, HS; Watanabe, Y | 1 |
| Carling, D; Davies, SP; Hardie, DG; Smith, FC; Wilson, WA | 1 |
| Brasseur, R; Charlier, P; Fonzé, E; Nguyen-Distèche, M; Vermeire, M | 1 |
| Fukushima, T; Minje, L; Mishina, M; Ogurusu, T; Sakata, K; Shingai, R; Taira, H | 1 |
| Hsieh, TS; Liu, AA; Liu, LF; Mao, Y; Nitiss, JL; Wang, H; Yu, C | 1 |
| Johnson, ER; McKay, DB | 1 |
| Feng, YM; Li, HM; Wang, DC; Yao, ZP; Zeng, ZH; Zhang, Y | 1 |
| Lei, B; Moore, C; Tu, SC | 1 |
| Almeida, A; Bolaños, JP; Heales, SJ; Medina, JM; Vega-Agapito, V | 1 |
| De Santis, A; Di Cosmo, A; Di Cristo, C; Messenger, JB; Nardi, G | 1 |
| Estevez, AY; O'Regan, MH; Phillis, JW; Song, D | 1 |
| Konings, WN; Lolkema, JS; Slotboom, DJ; Sobczak, I | 1 |
| Wickelgren, I | 1 |
| He, QP; Li, PA; Miyashita, H; Shuaib, A; Siesjö, BK; Warner, DS | 1 |
| Erasmus, E; Pretorius, PJ; van der Westhuizen, FH | 1 |
| Barna, K; Gaál, D; Hudecz, F; Kajtár, J; Mezö, G; Reményi, J | 1 |
| Christian, FA; Jackson, RN; Tate, TM | 1 |
| Corzo, N; del Castillo, MD; Olano, A; Sanz, ML | 1 |
| Barrientes, S; Cooke, C; Goodrich, DW | 1 |
| Huang, X; Raushel, FM | 1 |
| Lallès, JP; Montagne, L; Toullec, R | 1 |
| Edwards, RH; Klumperman, J; Krantz, DE; Liu, Y; Oorschot, V; Tan, PK; Waites, C; Wilson, RI | 1 |
| Bulinski, JC; Haino-Fukushima, K; Hisanaga, S; Hotani, H; Iida, J; Itoh, TJ; Kishimoto, T; Kitazawa, H; Murofushi, H; Ookata, K; Uchida, A | 1 |
| Eswar, N; Ramakrishnan, C | 1 |
| Fisone, G; Goiny, M; Goldstein, M; Haycock, J; Herrera-Marschitz, M; Hökfelt, T; Lindgren, N; Lindskog, M; Xu, ZQ | 1 |
| Argüello, JM; Berlin, JR; Peluffo, RD | 1 |
| Kawaguchi, N; Nishikawa, T; Tsuchida, H; Umino, A; Yamamoto, N | 1 |
| Cai, Z; Conn, PJ; Hubalek, F; Macek, TA; Murphy, TJ; Pohl, J; Schaffhauser, H | 1 |
| Ferry, JG; Tripp, BC | 1 |
| Nicklas, WJ; Zeevalk, GD | 1 |
| Deguchi, T; Fukuda, H; Ishihara, S; Kawada, Y; Yasuda, M; Yokoi, S | 1 |
| Prakash, V; Rao, JV; Rao, NA; Savithri, HS | 1 |
| Fei, J; Guo, LH; Huang, F; Li, J; Schwarz, W | 1 |
| Doronina, NV; Tourova, TP; Trotsenko, YA | 1 |
| Brandt, R; Eidenmüller, J; Fath, T; Hellwig, A; Reed, J; Sontag, E | 1 |
| Chen, C; de Riel, JK; Huang, P; Javitch, JA; Li, J; Liu-Chen, LY; Xu, W | 1 |
| Doyle, SA; Fung, SY; Koshland, DE | 1 |
| Davies, PL; Elce, JS; Hosfield, CM; Jia, Z; Moldoveanu, T | 1 |
| Håkansson, K; Miller, CG; Wang, AH | 1 |
| Ayala-Sanmartin, J; Gouache, P; Henry, JP | 1 |
| Hashimoto, A; Kanda, J; Oka, T | 1 |
| Kraynov, VS; Liu, J; Showalter, AK; Tsai, MD; Zhong, X | 1 |
| Bhattacharya, SS; Deery, EC; Hunt, DM; Newbold, RJ; Srinivasan, N; Walker, CE; Warren, MJ; Wilkie, SE | 1 |
| Alape-Girón, A; Basak, AK; Carr, FJ; Carter, G; Flores-Díaz, M; Holley, J; Keyte, M; Miller, J; Moss, DS; Naylor, CE; Thelestam, M; Titball, RW; Walker, N | 1 |
| Flink, R; Hillered, L; Kihlström, L; Lindquist, C; Nie, JX; Olsson, Y; Ronne Engström, E; Silander, HC | 1 |
| Barañano, DE; Ferris, CD; Snyder, SH | 1 |
| Behlke, J; Golbik, R; Hübner, G; Kriegel, TM; Müller, E; Naumann, M; Otto, A; Reuter, R | 1 |
| Oikonomakos, NG; Skamnaki, VT | 1 |
| Bibb, JA; Czernik, AJ; Greengard, P; Hisanaga , S; Horiuchi, A; Lan, M; Nairn, AC; Nishi, A; O'Callaghan, JP; Saito, T; Snyder, GL; Ule, J | 1 |
| Beernink, PT; Doyle, SA; Koshland, DE | 1 |
| Antignani, A; Cubellis, MV; D'Alessio, G; Naddeo, M; Russo, A | 1 |
| Briggs, C; Haefele, A; Ligeti, E; Mincone, L; Phelps, A; Wohlrab, H | 1 |
| Han, H; Liu, G; Shangguan, D; Zhao, R; Zhao, Y | 1 |
| Miranda, R; Orrego, F; Saldate, C | 1 |
| Batra, R; Khayat, R; Lagacé, L; Massariol, MJ; Tong, L | 1 |
| Akaike, A; Honda, K; Kihara, T; Nakamizo, T; Sawada, H; Shibasaki, H; Shimohama, S | 1 |
| Farrens, DL; Janz, JM | 1 |
| Kimmich, GA; Manglapus, M; Randles, J; Roussie, J | 1 |
| Chuang, DT; Chuang, JL; Mandel, H; Sansaricq, C; Wynn, RM | 1 |
| Klonowski, W | 1 |
| Epand, RF; Epand, RM; Martin, I; Ruysschaert, JM | 1 |
| Gouaux, E; Mayer, ML; Olson, R | 1 |
| Abdulrazzaq, YM; Ibrahim, A | 1 |
| Jin, W; Weng, Q | 1 |
| Chen, Y; Ghosh, G; Huxford, T; Malek, S | 1 |
| Nishikawa, T; Tomita, U; Umino, A; Yamamoto, N | 1 |
| Fukui, Y; Jung, YG; Lee, ES; Sakata, T | 1 |
| Lane, WS; Pflum, MK; Schreiber, SL; Tong, JK | 1 |
| Capony, JP; Chebli, K; Gallouzi, IE; Mouaikel, J; Tazi, J; Tourrière, H; van der Geer, P | 1 |
| Mothet, JP | 1 |
| Lamkin, MS; Lindhe, P | 1 |
| Häring, H; Jacob, S; Machicao, F; Rettig, A; Stumvoll, M; Wahl, HG | 1 |
| Jackson, VN; Price, NT; Zammit, VA | 1 |
| Antholine, WE; Brown, NM; Eisenstein, RS; Kennedy, MC; Walden, WE | 1 |
| Jacobsen, MD; Jorgensen, PL; Pedersen, PA | 1 |
| Cheng, Q; Gouaux, E; Jayaraman, V; Thiran, S; Yernool, D | 1 |
| Awobuluyi, M; Chatterton, JE; Cui, J; Lipton, SA; Nakanishi, N; Premkumar, LS; Sevarino, KA; Shin, Y; Takahashi, H; Talantova, M; Tong, G; Tu, S; Zhang, D | 1 |
| Sheibani, N; Sorenson, CM | 1 |
| Cates, MS; Phillips, GN; Teodoro, ML | 1 |
| Bae, CD; Jeon, S; Kim, S; Kim, YS; Park, J; Park, JB; Suh, PG | 1 |
| Chen, H; Dong, LQ; He, H; Liu, F; Quon, MJ; Wick, KR; Wick, MJ | 1 |
| Crossthwaite, AJ; Ip, JK; Perkinton, MS; Williams, RJ; Wood, GL | 1 |
| Allocati, N; Casalone, E; Di Ilio, C; Favaloro, B; Masulli, M; Parker, MW; Santucci, S | 1 |
| Skafar, DF; Zhong, L | 1 |
| Ellory, JC; Gibson, JS; Kiessling, K; Roberts, N | 1 |
| Carriero, MV; Cito, L; Del Pozzo, G; Fontana, L; Franco, P; Gargiulo, L; Guardiola, J; Iaccarino, C; Stoppelli, MP; Vocca, I | 1 |
| Ho, L; Mirjany, M; Pasinetti, GM | 1 |
| Hamada, Y; Inoue, M; Matsumoto, T; Okazaki, M; Taira, M; Takahashi, J | 1 |
| Baethmann, A; Eriskat, J; Fürst, M; Plesnila, N; Stoffel, M | 1 |
| Alam, M; Lehner, R; Vance, DE | 1 |
| Gonzàlez-Meler, MA; Siedow, JN; Sweet, CR; Umbach, AL | 1 |
| Ajima, R; K-Tsuzuku, J; Nakamura, T; Suzuki, T; Yamamoto, T; Yoshida, Y | 1 |
| Davidson, AR; Maxwell, KL; Northey, JG | 1 |
| Digicaylioglu, M; Everall, IP; Everson, A; Hashimoto, M; Langford, D; Mallory, M; Masliah, E; Sagara, Y | 1 |
| Levit, MN; Stock, JB | 1 |
| Hisanaga, S; Ishiguro, K; Isobe, T; Saito, T; Sasaki, T; Taoka, M; Uchida, A | 1 |
| Ballard, TM; Bluethmann, H; Borroni, E; Higgins, GA; Kemp, JA; Kew, JN; Mutel, V; Ouagazzal, AM; Pauly-Evers, M | 1 |
| Drejer, AH; Schatz, DG; Tsai, CL | 1 |
| Eiden-Assmann, S; Felsche, J; Heiss, A; Hoetzer, KA; Viertelhaus, M | 1 |
| Barnard, DC; Li, J; Patton, JG | 1 |
| Brändén, M; Brzezinski, P; Gennis, RB; Tomson, F | 1 |
| Amler, E; Ettrich, R; Hofbauerová, K; Kopecký, V; Krumscheid, R; Kubala, M; Plásek, J; Schoner, W; Teisinger, J | 1 |
| Ghosh, S; Marienfeld, RB; May, MJ | 1 |
| Hiasa, H | 1 |
| Chen, EY; Clarke, DM | 1 |
| Husted, S; Mattsson, M; Möllers, C; Schjoerring, JK; Wallbraun, M | 1 |
| Kang, T; Park, HI; Sang, QX; Suh, Y; Tschesche, H; Zhao, YG | 1 |
| Hori, M; Kitagawa, K; Kuwabara, K; Mabuchi, T; Matsumoto, M; Omura-Matsuoka, E; Sasaki, T; Sugiura, S; Takasawa, K; Tanaka, S | 1 |
| Brennan, TJ; Sluka, KA; Zahn, PK | 1 |
| Kaberlein, JJ; Luo, RT; Polak, PE; Simone, F; Thirman, MJ | 1 |
| Armstrong, RN; Codreanu, SG; Dirr, HW; Hornby, JA | 1 |
| Berndt, KD; Chiaraluce, R; Consalvi, V; Ladenstein, R; Lebbink, JH | 1 |
| Agerholm-Larsen, B; Chen, W; Linsel-Nitschke, P; Martinez, LO; Silver, DL; Tall, AR; Wang, N | 1 |
| Polgár, L; Sárkány, Z | 1 |
| Bai, XZ; Sun, LG; Yang, J; Zhou, HT | 1 |
| Beugnet, A; Li, W; Parra, JL; Proud, CG; Wang, X | 1 |
| Funahashi, HO; Kikuchi, A; Nakagawa, Y; Nakao, A; Sawada, M; Suda, N; Suzuki, M; Takami, Y; Yoshida, S | 1 |
| Barboric, M; Blackwell, TK; Peterlin, BM; Zhang, F | 1 |
| Elce, JS; Huynh, KK; Jia, Z; Smith, SD; Wells, A | 1 |
| Bulgakova, VG; Orlova, TI; Polin, AN | 1 |
| Clark, S; Leever, JD; Partin, KM; Weeks, AM | 1 |
| Lariosa-Willingham, KD; Rao, TS; Yu, N | 1 |
| Daiho, T; Danko, S; Iizuka, H; Suzuki, H; Wang, G; Yamasaki, K | 1 |
| Bayer, P; Fischer, G; Rahfeld, JU; Reimer, T; Ruecknagel, PK; Schierhorn, A; Weiwad, M | 1 |
| Ajlouni, A; Beucler, I; Bruckert, E; Chadarevian, R; Foubert, L; Giral, P; Kottler, ML; Raisonnier, A; Turpin, G | 1 |
| Elia, L; Pusch, M; Traverso, S | 1 |
| Hartson, SD; Matts, RL; Prince, T; Shao, J | 1 |
| Choli-Papadopoulou, T; Gerassimou, C; Kalpaxis, DL; Leontiadou, F; Papadopoulos, G; Xaplanteri, MA | 1 |
| Gajhede, M; Ipsen, H; Larsen, JN; Mirza, O; Spangfort, MD; Van Neerven, RJ | 1 |
| Ayala-Sanmartin, J; Liu, J; Rothermund, CA; Vishwanatha, JK | 1 |
| BLAKLEY, RL | 1 |
| ORMSBEE, RA; PEACOCK, MG | 1 |
| Deng, Y; Nicholson, RA | 1 |
| Arteaga, GM; Burkart, EM; Prabhakar, R; Solaro, RJ; Sumandea, MP; Wieczorek, DF | 1 |
| Chae, CH; Kim, KK; Kwon, HB; Lee, CJ; Maiti, K; Oh, da Y; Oh, DY; Seong, JY; Wang, C; Yun, O | 1 |
| Dodson, ML; Lloyd, RS; Meador, MG; Rajagopalan, L | 1 |
| Amagai, M; Hanakawa, Y; Lin, C; Nishifuji, K; Schechter, NM; Stanley, JR | 1 |
| Chiu, LY; Rameau, GA; Ziff, EB | 1 |
| Delbaere, LT; Hayakawa, K; Leduc, Y; Prasad, L | 1 |
| Chen, SJ; Chen, WF; Huang, LT; Lai, MC; Lin, SZ; Tao, PL; Wang, CL; Yang, CH; Yang, SN | 1 |
| Agretti, P; Ceccarini, G; Chiellini, C; Chiovato, L; Lisi, S; Maffei, M; Mammoli, C; Marsili, A; Pelosini, C; Pinchera, A; Rosellini, V; Santini, F; Scartabelli, G; Tonacchera, M; Vitti, P | 1 |
| Gerber, D; Sal-Man, N; Shai, Y | 1 |
| Crawford, E; Hendzel, MJ; Lever, MA; Th'ng, JP | 1 |
| Colas, C; De Montellano, PR | 1 |
| Bade-Doeding, C; Blasczyk, R; Eiz-Vesper, B; Elsner, HA; Holtkamp, U; Seltsam, A | 1 |
| Bulychev, A; Golemi-Kotra, D; Kim, C; Meroueh, SO; Mobashery, S; Stemmler, AJ; Stemmler, TL; Vakulenko, SB | 1 |
| di Salvo, ML; Musayev, FN; Safo, MK; Schirch, V; Szebenyi, DM | 1 |
| Fujishiro, M; Goshima, Y; Ishii, T; Kitamura, H; Masuda, M; Matsuse, T; Teramoto, S | 1 |
| Bräuner-Osborne, H; Greenwood, JR; Hermit, MB | 1 |
| Dowling, M; Kao, GD; Liu, F; Yang, XJ | 1 |
| Amler, E; Ettrich, R; Kubala, M; Kutý, M; Lánský, Z; Plásek, J; Schoner, W; Teisinger, J | 1 |
| Henzl, MT; Larson, JD; Lee, YH; Tanner, JJ | 1 |
| Chen-Hwang, MC; Dolios, G; Huang, Y; Hwang, YW; Murakami, N; Padovan, JC; Wang, R | 1 |
| Kwak, EJ; Lim, SI | 1 |
| Brunak, S; Gupta, R; Kiemer, L; la Cour, T; Mølgaard, A; Skriver, K | 1 |
| Chang, BS; Ganim, Z; Kazmi, MA; Mathies, RA; Sakmar, TP; Yan, EC | 1 |
| Banerjee, A; Chang, C; Helsper, F; Khantwal, CM; Phelps, MA; Swaan, PW; Zhang, EY | 1 |
| Ishiguro, M | 1 |
| Ciani, B; Jourdan, M; Searle, MS | 1 |
| Morinaga, N; Nakayama, K; Noda, M; Shin, HW | 1 |
| Bethel, CR; Bonomo, RA; Knox, JR; Sun, T | 1 |
| Concas, A; Marino, G; Minei, R; Pierobon, P; Porcu, P; Sogliano, C; Tino, A; Tortiglione, C | 1 |
| Chan, HH; Chan, LN; Chang, DC; Han, Y; Lee, NT; Li, M; Li, W; Pi, R; Pu, Y; Sucher, NJ | 1 |
| Granados, J; Hernández-Pacheco, G; Murguía, LE; Pérez-Hernández, N; Reyes, PA; Soto, ME; Vargas-Alarcón, G | 1 |
| Daubner, SC; Fitzpatrick, PF; Royo, M | 1 |
| Aizawa, H; Barrow, RK; Ghosh, A; Huang, AS; Huganir, RL; Kashani, AH; Kim, PM; Kim, PS; Snyder, SH; Wickramasinghe, SR | 1 |
| Alberts, AS; Carr, HS; Frost, JA; Qin, H | 1 |
| Cheong, HI; Choi, Y; Ha, IS; Kang, HG; Kang, JH; Lee, JH; Lee, JW; Lee, SJ; Zheng, SH | 1 |
| Golabek, AA; Kida, E; Walus, M; Wisniewski, KE | 1 |
| Hayase, K; Lyou, S; Sano, A; Tujioka, K; Yokogoshi, H | 1 |
| Breazeale, SD; Naismith, JH; Raetz, CR; Williams, GJ | 1 |
| Abali, EE; Banerjee, D; Bertino, JR; Menon, LG; Mishra, PJ; Peters, R; Skacel, N | 1 |
| Voth, GA; Xu, J | 1 |
| Koshland, DE; Kwan, G; Lu, CJ; Radisky, ES | 1 |
| Huang, HW; Inoue, M; Kataoka, K; Kitagawa, R; Naruse, D; Sakurai, T | 1 |
| Finazzi, G; Hippler, M; Sommer, F | 1 |
| Huffman, HA; Lappe, JW; Patel, HN; Sniegowski, JA; Wachter, RM | 1 |
| Kang, K; Kinjo, TG; Schnetkamp, PP; Szerencsei, RT; Winkfein, RJ | 1 |
| Li, ZF; Wang, HH; Wang, JD; Xie, J; Yang, YP; Zhang, M; Zhong, Y | 1 |
| Cheifetz, MN; Fridkin, M; Millar, RP; Naor, Z; Pawson, AJ; Shacham, S | 1 |
| Jia, J; Shen, B; Tao, Y; Wang, Y; Zeng, R | 1 |
| Edwards, RA; Glover, JN; Lee, MS; Thede, GL | 1 |
| González, MI; Krizman-Genda, E; Robinson, MB; Zelenaia, O | 1 |
| Carbone, A; Madden, R | 1 |
| Aronoff, DM; Brock, TG; Flamand, N; Jones, SM; Luo, M; Peters-Golden, M | 1 |
| Fisher, JF; Meroueh, SO; Mobashery, S; Schlegel, HB | 1 |
| Bowser, MT; Ciriacks, CM | 1 |
| Horváth, R; Jaksch, M; Lochmüller, H; Müller-Höcker, J; Schoser, BG; Völpel, M | 1 |
| Dememes, D; Mothet, JP; Nicolas, MT | 1 |
| Bhanumathy, C; Joseph, SK; Khan, MT; Wagner, L; Yule, DI | 1 |
| Diaz, CM; Macnab, LT; Pow, DV; Sullivan, RK; Williams, SM | 1 |
| Ahlers, BA; Carl, LL; Cheung, JY; Moorman, JR; Mounsey, JP; Rothblum, LI; Song, J; Tucker, AL; Wang, J; Zhang, XQ | 1 |
| Hashimoto, K; Hayashi, Y; Ishibashi, H; Nakanishi, H | 1 |
| Brooks, CL; Schenck, EJ | 1 |
| Ishida, T; Kamigauchi, M; Nagata, H; Nishi, H | 1 |
| Dash, PK; Kobori, N; Moore, AN | 1 |
| Anggono, V; Cousin, MA; Graham, ME; Robinson, PJ; Smillie, KJ; Valova, VA | 1 |
| Ashby, CR; Kawahara, R; Maeda, K; Mitani, H; Shirayama, Y; Yamada, T | 1 |
| Chen, PE; Johnston, AR; Lipscombe, D; Wyllie, DJ | 1 |
| Billard, JM; Junjaud, G; Mothet, JP; Rouaud, E; Turpin, F | 1 |
| Oliet, SH; Panatier, A; Piet, R | 1 |
| Baldeck, JD; Marquis, RE; Nguyen, PT; Olsson, J; Sheng, J | 1 |
| Cassady, CJ; Li, Z; Yalcin, T | 1 |
| Altamirano, C; Becerra, S; Cairó, JJ; Gòdia, F; Illanes, A | 1 |
| Solís, JM; Suárez, LM | 1 |
| Guo, H; Nakayama, T; Wlodawer, A; Xu, Q | 1 |
| Amorós, A; Carrato, A; Hernández, S; Kogevinas, M; Lloreta, J; López-Knowles, E; Malats, N; Real, FX; Serra, C; Tardón, A | 1 |
| Baker, GB; Grant, SL; Hampson, DR; Shulman, Y; Tibbo, P | 1 |
| Graeff, R; Hao, Q; Kriksunov, IA; Lee, HC; Liu, Q; Munshi, C | 1 |
| Jüttner, F; Walsby, AE | 1 |
| Boltshauser, E; Koch, J; Mayr, J; Sperl, W; Strassburg, HM | 1 |
| Fox, JM; Najarro, P; Pease, JE; Proost, P; Smith, GL; Struyf, S | 1 |
| Shoji, Y; Terashima, T; Yamagata, K; Yokogoshi, H | 1 |
| Chan, SS; Copeland, WC; Longley, MJ | 1 |
| Agam, G; Amar, S; Bendikov, I; De Miranda, J; Nadri, C; Panizzutti, R; Wolosker, H | 1 |
| Pace, CN; Scholtz, JM; Trevino, SR | 1 |
| Brown, SD; Chelly, J; Cleak, J; Cowan, NJ; Davies, KE; Dear, N; Flint, J; Fray, M; Harvey, RJ; Huang, GJ; Keays, DA; Molnár, Z; Nolan, P; Oliver, PL; Piñon, MC; Poirier, K; Rawlins, JN; Siebold, C; Tian, G; Valdar, W | 1 |
| Fu, YH; Jones, CR; Ptácek, LJ; Shin, JY; Toh, KL; Xu, Y | 1 |
| Ariani, F; Cambi, F; Ciacci, G; Malandrini, A; Mari, F; Mencarelli, MA; Renieri, A; Rossi, S; Squillaro, T; Ulivelli, M | 1 |
| Chorny, I; Groban, ES; Jacobson, MP; Levine, E; Mandell, DJ; Rapp, CS; Wong, SE | 1 |
| Acosta, GB; Scolari, MJ | 1 |
| Hassel, B; Henjum, S | 1 |
| Chen, X; Ciufo, LF; Craig, TJ; Gillis, KD; Morgan, A; Takahashi, M; Yang, Y | 1 |
| Casado, FJ; Montaño, A; Rejano, L; Sánchez, AH | 1 |
| Kanner, BI; Teichman, S | 1 |
| Hashimoto, K; Iyo, M; Sawa, A | 1 |
| Bai, D; Gong, XQ; Zabek, RL | 1 |
| Itakura, M; Takahashi, M; Yamamori, S | 1 |
| Chatterjee, N; Daugherty, SE; Fallin, MD; Hayes, RB; Huang, WY; Isaacs, WB; Platz, EA; Shugart, YY; Welch, R | 1 |
| Fraser, ME; Rochet, JC; Tammam, SD | 1 |
| Aiso, S; Chiba, T; Matsuoka, M; Nishimoto, I; Okamoto, K; Sasabe, J; Yamada, M | 1 |
| Alvarez-Arias, DA; Campbell, KS | 1 |
| Lamas, M; Lee-Rivera, I; López-Colomé, AM; Ramírez, M | 1 |
| Fukunaga, K; Matsuzaki, K; Mimaki, Y; Miyazaki, K; Moriguchi, S; Nakata, N; Ohizumi, Y; Sakai, S; Sashida, Y; Yamakuni, T; Yawo, H; Yokosuka, A | 1 |
| Cane, DE; Christianson, DW; Jiang, J; Vedula, LS; Zakharian, T | 1 |
| Butinar, D; Christodoulou, K; Koutsou, P; Starr, A; Zidar, J | 1 |
| Fumagalli, E; Funicello, M; Gobbi, M; Mennini, T; Rauen, T | 1 |
| Demuth, HU; Gärtner, UT; Heiser, U; Hoffmann, T; Ito, K; Nakajima, Y; Oyama, H; Xu, Y; Yoshimoto, T; Zheng, H | 1 |
| Boulianne, GL; Commisso, C | 1 |
| Grabstein, K; Johnson, RS; Tirrell, DA; Wang, A; Winblade Nairn, N | 1 |
| Bernard, F; Caboche, J; Kappes, V; Lavaur, J; Pagès, C; Pascoli, V; Trifilieff, P; Vanhoutte, P | 1 |
| Ahmed, M; Bhuiyan, MA; Hossain, M; Ishiguro, M; Nagaoka, Y; Nagatomo, T; Nakamura, T; Watanabe, M | 1 |
| Chavira-Suárez, E; Lamas, M; Ramírez, M | 1 |
| Aperia, A; Axehult, G; Bondar, A; Brismar, H; Gunnarson, E; Krieger, P; Song, Y; Zelenin, S; Zelenina, M | 1 |
| Mothet, JP; Oliet, SH | 1 |
| Lonart, G; Simsek-Duran, F | 1 |
| Baldini, G; Bettati, S; Bosisio, C; Campanini, B; Chirico, G; Collini, M; D'Alfonso, L; Quercioli, V; Raboni, S | 1 |
| Abrahmsén, L; Ekblad, T; Feldwisch, J; Karlström, AE; Orlova, A; Tolmachev, V; Tran, T; Wennborg, A; Widström, C | 1 |
| Choi, MA; Choi, SJ; Hwang, JH; Kim, MS; Lee, JH; Park, BR | 1 |
| Eguchi, Y; Hirata, K; Ishida, C; Matsuda, K; Ozoe, F; Ozoe, Y; Sakai, K | 1 |
| Danger, G; Ross, D | 1 |
| Fukuma, G; Hase, K; Hirose, S; Kaneko, S; Kijima, H; Kishi, A; Kojima, T; Mitsudome, A; Miura, Y; Mori, F; Ohno, H; Okada, M; Saito, R; Sato, A; Takahara, T; Takano, Y; Tomiyama, M; Ueno, S; Wakabayashi, K; Yoshida, S; Zhu, G | 1 |
| Baude, A; Brachet, A; Bréchet, A; Dargent, B; Fache, MP; Ferracci, G; Irondelle, M; Leterrier, C; Pereira, S | 1 |
| Galocha, B; García-Medel, N; Gómez, P; López de Castro, JA; Mavian, C | 1 |
| Holyavka, MG; Kovaleva, TA; Kozhedub, SV; Rezvan, SG | 1 |
| Erskine, MS; Lin, AW; Man, HY; Oberlander, JG | 1 |
| Bowie, D; Brown, P; Corbeil, CR; Fay, AM; Moitessier, N | 1 |
| Gough, JE; Hirst, AR; Hodson, NW; Jayawarna, V; Richardson, SM; Saiani, A; Ulijn, RV | 1 |
| Oomens, J; Redlich, B; Steill, JD | 1 |
| Clavel, T; Lindley, ND; Ouhib-Jacobs, O; Schmitt, P | 1 |
| Oja, SS; Saransaari, P | 1 |
| Kass-Simon, G; Kay, JC | 1 |
| Drago, F; Frasca, A; Fumagalli, F; Pasini, M; Racagni, G; Riva, MA | 1 |
| Drew, KL; Green, TK; Kirschner, DL; Wilson, AL | 1 |
| Cheriyan, J; Devi Suma Priya, S; James, J; Mayadevi, M; Omkumar, RV; Pradeep, KK; Raveendran, R; Sanalkumar, R; Santhoshkumar, TR; Steephan, M | 1 |
| Panatier, A | 1 |
| Ahn, YH; Choi, HJ; Kang, HJ; Kim, H; Lee, H; Paik, YK; Shin, JS; Yoo, JS; Youn, JH | 1 |
| Aguilera, J; Barrera, I; Castelán, F; González-Mejia, E; Hernández-Kelly, LC; López-Bayghen, E; Melgarejo, Y; Ortega, A; Suárez-Pozos, E; Zepeda, RC | 1 |
| Daiho, T; Danko, S; Liu, X; Suzuki, H; Wang, G; Yamasaki, K | 1 |
| Riemen, AJ; Waters, ML | 1 |
| Bibow, S; Biernat, J; Blackledge, M; Fischer, D; Griesinger, C; Mandelkow, E; Mukrasch, MD; Zweckstetter, M | 1 |
| Barbar, E; Benison, G; Chiodo, M; Karplus, PA | 1 |
| Ahn, SM; Choe, ES | 1 |
| Ahabrach, H; Boix, J; ElMlili, N; Errami, M; Felipo, V; Rodrigo, R | 1 |
| Darra, E; Ebner, FH; Mariotto, S; Shoji, K; Suzuki, H | 1 |
| Halassa, MM; Haydon, PG | 1 |
| Ghasemi, M; Lewin, J; Mani, AR; Moore, KP; Rezania, F | 1 |
| Chen, ZQ; Jiang, ZL; Li, X; Peng, LL; Wang, GH | 1 |
| Boules, M; Gordillo, A; Li, Z; Liang, Y; Richelson, E | 1 |
| Kim, KH; Santos, NC | 1 |
| Attwell, D; Hamilton, NB | 1 |
| Chen, NH; Liu, ZJ; Xue, JF; Zhang, Y; Zhao, M | 1 |
| Andersen, JP; Clausen, JD | 1 |
| Benedetti, B; Boresch, M; Kettenmann, H; Müller, J; Nolte, C; Pivneva, T; Reyes-Haro, D; Scheller, A | 1 |
| Aiso, S; Sasabe, J | 1 |
| Caffino, L; Frasca, A; Fumagalli, F; Gass, P; Racagni, G; Riva, MA; Sprengel, R; Vogt, MA | 1 |
| Chiriac, M; Lupan, I; Palibroda, N; Popa, F; Popescu, O | 1 |
| Donnelly, D; Mann, RJ; Nasr, NE; Paci, E; Sinfield, JK | 1 |
| Arancibia-Carcamo, IL; Griffin, LD; Kittler, JT; MacAskill, AF; Muir, J; Smith, KR | 1 |
| Blanchard, JS; Hegde, SS; Vetting, MW | 1 |
| Culka, A; Edwards, HG; Jehlička, J | 1 |
| Blackwood, DH; Fujii, K; Fukushima, Y; Hashimoto, K; Kano, S; Kunugi, H; Malloy, MP; Muir, WJ; Ozeki, Y; Pickard, BS; Sawa, A; Shirayama, Y; Sun, DQ; Wakui, K; Zeledon, M | 1 |
| Dupouy, C; Kaminski, PA; Padilla, A; Pochet, S; Zhang, C | 1 |
| Bergerot, D; Caudal, D; Godsil, BP; Jay, TM; Mailliet, F | 1 |
| Choi, JH; Murray, JW; Wolkoff, AW | 1 |
| Labrie, V; Roder, JC; Wong, AH | 1 |
| Nishikawa, T | 2 |
| Hazra, S; Konrad, M; Lavie, A; Ort, S; Szewczak, A | 1 |
| Cluett, WR; Mahadevan, R; Yang, L | 1 |
| Hayase, K; Ohsumi, M; Tujioka, K; Yokogoshi, H | 1 |
| Barbier, D; Barnych, B; Lin, JS; Marinesco, S; Maucler, C; Meiller, A; Pollegioni, L; Vasylieva, N | 1 |
| Barretina, J; Barrett, FG; Birsoy, K; Brachtel, EF; Chan, AM; Chen, WW; Cowley, GS; Driggers, EM; Garraway, LA; Hsu, PP; Jang, HG; Jha, AK; Kalaany, NY; Kim, D; Marks, KM; Mino-Kenudson, M; Ottina, K; Pacold, ME; Possemato, R; Root, DE; Sabatini, DM; Sethumadhavan, S; Shaul, YD; Stransky, N; Tsun, ZY; Woo, HK; Yuan, B | 1 |
| Motomura, E; Nakagawa, M; Okada, M; Tanahashi, S; Yamamura, S | 1 |
| Bergersen, LH; Bouvier, D; Gundersen, V; Larsson, M; Morland, C; Ormel, L; Ottersen, OP; Rinholm, JE; Røe, AT; Santello, M; Stranna, A; Volterra, A; Wold, JF | 1 |
| Barger, SW; Fang, J; Jiang, H; Qu, J; Sun, L; Wu, B; Wu, S; Yin, G | 1 |
| Combs, B; Gamblin, TC; Voss, K | 1 |
| Kato, F; Shigetomi, E | 1 |
| Anderson, CM; Anderson, HD; Knox, JD; LeMaistre, JL; Lu, L; Sanders, SA; Stobart, MJ | 1 |
| Feng, Z; Gorelenkova, O; Yang, J; Zheng, M | 1 |
| De Bundel, D; Gómez-Galán, M; Lindskog, M; Smolders, I; Van Eeckhaut, A | 1 |
| Cameron, A; Gong, Z; Harrington, J; Lockridge, A; Newland, B; Romero, G; Yuan, LL | 1 |
| Balu, DT; Coyle, JT | 1 |
| Cameselle-Teijeiro, JM; Couto, JP; Faustino, A; Lopes, JM; Pardal, F; Pópulo, H; Rocha, AS; Soares, P; Sobrinho-Simões, M | 1 |
| Edman, S; Hardingham, GE; Livesey, MR; Macdonald, LJ; McKay, S; Samadi, M; Wyllie, DJ | 1 |
| Ben Achour, S; Pascual, O | 1 |
| Erdődi, F; Kőszeghy, Á; Lontay, B; Pál, B; Rusznák, Z; Serfőző, Z; Szücs, G | 1 |
| Guillem, AM; López, E; María López-Colomé, A; Martínez-Lozada, Z; Ortega, A | 1 |
| Dai, K; Hoshikawa, M; Niwa, O; Okada, M; Saito, H; Suzuki, N; Yamamura, S | 1 |
| Chi, S; Park, D; Park, E | 1 |
| Cheung, MC; Cheung, ZH; Ip, NY; Lai, KO; Liang, Z; Lok, KC; Palko, ME; Tessarollo, L; Wong, AS; Xie, H; Xu, P; Yung, WH | 1 |
| Kameda, T; Sutherland, TD; Walker, AA; Weisman, S | 1 |
| Balen, AH; Campbell, BK; Hemmings, KE; Hogg, JE; Leese, HJ; Maruthini, D; Picton, HM; Vyjayanthi, S | 1 |
| Gao, M; Jiang, E; Weng, HR; Yan, X | 1 |
| Ryan, RM; Scopelliti, AJ; Vandenberg, RJ | 1 |
| Courchet, J; Courchet, V; Mairet-Coello, G; Maximov, A; Pieraut, S; Polleux, F | 1 |
| Bechberger, JF; Kozoriz, MG; Lai, S; Naus, CC; Sáez, JC; Sin, WC; Vega, JL | 1 |
| Rozsa, E; Vigh, J | 1 |
| Baker, GB; Churchward, MA; Dhami, KS; Todd, KG | 1 |
| Ankonina, G; Brif, A; Drathen, C; Pokroy, B | 1 |
| Eidne, KA; Jaeger, WC; Pfleger, KD; Seeber, RM | 1 |
| Martineau, M | 1 |
| Ahn, HJ; Kim, JH; Kim, YW; Li, C | 1 |
| Li, X; Liu, YM; McCullm, C; Ou, XM; Xiao, D | 1 |
| Dudka, J; Oniszczuk, T; Poleszak, E; Serefko, A; Szopa, A; Wlaź, P; Wośko, S; Wróbel, A | 1 |
| Alzweiri, M; Bardaweel, SK; Ishaqat, AA | 1 |
| Cesaro, L; Donella-Deana, A; Marin, O; Pinna, LA; Venerando, A | 1 |
| Du, J; He, T; Jiang, H; Qu, J; Song, Z; Wu, S | 1 |
| Bukhory, DK; Dai, J; Fan, C; Huang, SY; Jia, P; Jin, N; Li, T; Li, WZ; Liu, K; Long, R; Su, GH; Wang, J; Wang, Z | 1 |
| Jones, RS; Lench, AM; Massey, PV; Pollegioni, L; Woodhall, GL | 1 |
| Angelucci, E; Antonini, G; Cervelli, M; Federico, R; Leboffe, L; Mariottini, P; Polticelli, F; Stano, P | 1 |
| Kong, Y; Li, Z; Liu, C; Liu, Y; Song, Y; Wang, H; Yang, J | 1 |
| Fujimoto, M; Fujita, Y; Hashimoto, K; Hashimoto, R; Ito, A; Numata, S; Ohi, K; Ohmori, T; Takeda, M; Umeda-Yano, S; Yamamori, H; Yasuda, Y | 1 |
| Chang, SW; Chen, SL; Hsu, PH; Liao, KY; Liu, WC; Tsao, YP | 1 |
| Hao, Y; Nair, SK; Ortega, MA; van der Donk, WA; Walker, MC; Zhang, Q | 1 |
| Ågren, H; Ekman, CJ; Fujita, Y; Hashimoto, K; Jakobsson, J; Landén, M; Pålsson, E; Sellgren, C; Södersten, K | 1 |
| Dor-Abarbanel, AE; Durrant, AR; Edelman, S; Hashimoto, K; Heresco-Levy, U; Javitt, DC; Levin, R | 1 |
| Hu, H; Li, X; Liu, YM; McCullum, C; Zhao, S | 1 |
| Balu, DT; Coyle, JT; Ishiwata, S; Nishikawa, T; Umino, A | 1 |
| Koizumi, S | 1 |
| Chakraborty, S; Lin, SH; Shiuan, D; Tai, DF | 1 |
| Akanuma, S; Hosoya, K; Kubo, Y; Zakoji, N | 1 |
| Bergersen, LH; Gundersen, V; Storm-Mathisen, J | 1 |
| Delay, ER; Delay, RJ; Pal Choudhuri, S | 1 |
| Albertini, G; Bentea, E; Demuyser, T; El Arfani, A; Massie, A; Smolders, I; Van Eeckhaut, A | 1 |
| Corn, CK; Hayano, M; Pagano, NC; Stockwell, BR; Yang, WS | 1 |
| Ebihara, T; Maruyama, K; Murayama, M; Takashima, A; Yagishita, S | 1 |
| Enohara, M; Fujita, Y; Hasegawa, T; Hashimoto, K; Hashimoto, T; Ishikawa, M; Iyo, M; Kanahara, N; Kimura, A; Nakazato, M; Niitsu, T; Sasaki, T; Shiina, A; Watanabe, H; Yoshida, T | 1 |
| Dai, T; Li, N; Liu, Q; Zhang, L; Zhang, Y | 1 |
| Geck, RC; Toker, A | 1 |
| Amar, M; Dallérac, G; Fossier, P; Le Roux, N; Levasseur, G; Meunier, CN; Mothet, JP; Pollegioni, L; Sacchi, S | 1 |
| de Freitas, IG; de Melo Reis, RA; Dos Santos Pereira, M; Kubrusly, RC; Lowe, J; Manhães, AC; Martins, RS; Pecinalli, NR; Santos, LE; Sathler, MF; Stutz, B; Taveira-da-Silva, R | 1 |
| Kitamura, T; Matsui, S; Sasaki, T | 1 |
| Baker, GB; Li, XM; Rauw, G; Wang, WQ; Zheng, HF | 1 |
| Derat, E; Driant, T; Nachon, F; Ollivier, C; Renard, PY | 1 |
| Brandon, NJ; Chadchankar, J; Deeb, TZ; Dunlop, J; Hyde, TM; Kang, JY; Mather, RJ; Mighdoll, MI; Moss, SJ; Pangalos, MN; Vien, TN | 1 |
| Balu, DT; Coyle, JT; Liebl, DJ; Loris, ZB; Perez, EJ; Sick, TJ; Tapanes, SA | 1 |
| Fujita, Y; Hashimoto, K; Iyo, M; Kanahara, N; Nakata, Y; Niitsu, T; Oda, Y; Oishi, K; Shirayama, Y; Takase, M | 1 |
| Lohwacharin, J; Takizawa, S; Yang, Y | 1 |
| Dallerac, G; Ezan, P; Giaume, C; Koulakoff, A; Leybaert, L; Meunier, C; Wang, N; Yi, C | 1 |
| Caetano, I; Correia, JS; Guerra-Gomes, S; Martins, M; Oliveira, JF; Pinto, L; Reis, JS; Sardinha, VM; Sousa, N; Tavares, G; Teixeira-Castro, A | 1 |
| Bill, A; Camargo, LM; Digan, ME; Guo, H; Niu, H; Pan, Y; Reiling, S; Shanker, YG; Soler-Llavina, G; Stams, T; Wang, HR; Weihofen, WA; Yeboah, F | 1 |
| Leow, TC; Rahman, RNZRA; Salleh, AB; Sani, HA; Shariff, FM | 1 |
| Bergman, J; Carlezon, WA; Coyle, JT; Desai, RI; Donahue, RJ; Doyle, MR; Landino, SM; Presti, KT; Puhl, MD; Takagi, S | 1 |
| Cai, Y; Chen, J; Chen, Y; Cui, L; Fu, J; Li, K; Li, Y; Liu, Z; Ma, G; Ma, Z; Mai, H; Qi, W; Sun, C; Sun, F; Tao, H; Xie, Q; Zhao, B; Zhao, J; Zhou, H; Zhou, X | 1 |
| Carvalho, PC; Correia, CRD; de Jesus, HCR; Drekener, RL; Ferrari, AJR; Fioramonte, M; Gozzo, FC; Lima, DB; Neves-Ferreira, AGDC; Oliveira, LG | 1 |
| Bortolotto, ZA; de Carvalho, CR; Formolo, DA; Hoeller, AA; Latini, A; Leal, RB; Lin, K; Linhares, MN; Lopes, MW; Prediger, RD; Sousa, DS; Walz, R; Wolf, P | 1 |
| Liu, X; Ma, Y; Wang, M; Xie, R; Yu, X; Yuan, Z | 1 |
| Bill, A; Guo, H; Yeboah, F | 1 |
| Guadagno, E; Li, C; Ramamurthy, J; Trakadis, Y; Wang, A; Wang, C; Zhang, E | 1 |
| Barnett, N; Faulkner, A; Hannapel, R; Parent, MB; Ross, A | 1 |
| Jung, JH; Kim, YS; Lee, SM; Seo, JA | 1 |
| Bernal, B; Blesbois, E; Castaño, C; Esteso, MC; Gil, MG; Gutiérrez-Adán, A; López-Sebastián, A; Pérez-Cerezales, S; Santiago-Moreno, J; Toledano-Díaz, A; Woelders, H | 1 |
| Araki, T; Fujioka, M; Hashimoto, K; Kasai, K; Kirihara, K; Koike, S; Koshiyama, D; Nagai, T; Suga, M; Tada, M; Usui, K | 1 |
| Bolognesi, P; Frassineti, M; Longo, F; Mercatelli, D; Morari, M; Pisanò, CA; Shimshek, DR | 1 |
| Katoh, H; Teramoto, K | 1 |
| Gonzalez-Pech, NI; Grassian, VH; Ustunol, IB | 1 |
| Garip, B; Kayir, H | 1 |
| Huang, L; Lian, J; Liu, W; Xu, Z; Zhu, X | 1 |
| Lane, HY; Lin, CH; Yang, HT | 1 |
| Gewirtz, JC; Matveeva, TM; Miller, RF; Pisansky, MT; Young, A | 1 |
| Apfel, UP; Duan, J; Eichmann, V; Happe, T; Heberle, J; Knör, G; Laun, K; Senger, M; Stripp, ST; Winkler, M; Wittkamp, F | 1 |
| Bhattacharjee, A; Biswal, S; Ghosh, AS; Issa, B; Jain, D; Kumar, G | 1 |
| Biswas, A; Chakraborty, A; Nandi, SK; Panda, AK | 1 |
| Bergthaler, A; Cai, Z; Demel, F; Fragner, L; Fritsch, SD; Haschemi, A; Hengstschläger, M; Katholnig, K; Linke, M; Mayr, HK; Miller, A; Nägele, T; Popa, A; Sun, X; Weckwerth, W; Weichhart, T; Wilson, JL | 1 |
| Fukuyama, K; Murata, M; Okada, M; Okubo, R; Shiroyama, T | 1 |
| Caputo, V; De Rosa, A; De Stefano, ME; Di Maio, A; Errico, F; Falco, G; Homma, H; Isidori, AM; Katane, M; Marotta, P; Mastrostefano, F; Nuzzo, T; Saitoh, Y; Usiello, A | 1 |
| Billard, JM; Freret, T; Ploux, E | 1 |
| Bhattiprolu, AK; Brzustowicz, LM; Clarke, SG; Crosta, CM; Dudzinski, NR; Firestein, BL; Fu, AY; Hernandez, K; Moore, JC; Paradiso, KG | 1 |
| But, SY; Khmelenina, VN; Mustakhimov, II; Reshetnikov, AS; Rozova, ON | 1 |
| Mony, L; Paoletti, P; Stroebel, D | 1 |
| Agostinho, P; Amaral, IM; Canas, PM; Cunha, RA; Gonçalves, FQ; Leitão, C; Lopes, C; Lopes, JP; Madeira, D; Pereira, MF | 1 |
| Acquarone, M; Barbosa, HS; Gonçalves, PFR; Menezes, JRL; Neves, GA; Panizzutti, R; Perozzo, AF; Poleto, A | 1 |
| Borkiewicz, L; Grela, P; Horbowicz-Drożdżal, P; Kamel, K; Kmiecik, S; Shaw, PC; Tchórzewski, M; Tumer, NE | 1 |
| Akkouh, IA; Andreassen, OA; Budinska, E; Djurovic, S; Grabiec, M; Hribkova, H; Kasparek, T; Sun, YM; Szabo, A | 1 |
| Bin, P; Wang, Y; Xu, S; Zhang, D; Zhu, G | 1 |
| Fai Au, D; Ostrovsky, D; Smith, MC; Vugmeyster, L | 1 |
| Cho, J; Chun, H; Chun, YE; Feng, J; Hong, J; Joo, J; Kang, H; Kim, S; Koh, W; Lee, CJ; Lee, J; Lee, SE; Li, Y; Oh, SJ; Park, M; Park, MG; Ryu, H; Sa, M; Shim, HS; Woo, J | 1 |
| Altenberg, GA; Carvajal, FJ; Cerpa, W; Fiori, MC; Gómez, GI; Jimenez, I; Jury, N; Linsambarth, S; Martin, C; Martínez, P; Mendez, L; Moraga-Amaro, R; Orellana, JA; Retamal, MA; Stehberg, J; Tamburini, G; van Zundert, B; Varela-Nallar, L; Verdugo, DA | 1 |
| Bak, K; Murshed, M; Parashar, A | 1 |
| Karakawa, S; Kawasaki, M; Mine, T; Nishitani, S; Sato, W; Shindo, D; Somekawa, S; Suzuki, K; Toyoda, S; Umeda, K | 1 |
| Curtis, GH; Hille, MB; Hirano, MS; Horton, EC; Huang, J; Kupai, A; Lackey, DL; Mathieson, CJ; Murayama, JF; Nakahara, H; Rodriguez, A; Shan, B; Voss, KM | 1 |
| Yeo, SY; Zou, W | 1 |
| Agarwal, D; Croset, V; Meschi, E; Otto, N; Park, A; Sims, D; Treiber, CD; Waddell, S | 1 |
| Aye Cho, TZ; Bry, L; Carmody, RN; Chadaideh, KS; Jung, J; Kalafut, KC; Koontanatechanon, A; Lewis, CA; Longchamp, A; MacArthur, MR; Mann, CG; Mitchell, JR; Mitchell, SJ; Ozaki, CK; Reynolds, JS; Tao, M; Treviño-Villarreal, JH; Trocha, KM; Yeliseyev, V | 1 |
| Chen, X; Ge, T; He, Z; Wang, J; Yuan, H; Zhang, L | 1 |
| de Laurentiis, U; Di Spiezio Sardo, A; Guida, M; Insabato, L; Lombardi, M; Mollo, A; Neola, D; Raffone, A; Richards, SM; Scala, G; Symes, SJK; Travaglino, A; Troisi, J | 1 |
| Chen, L; Gu, J; Huang, C; Kong, Q; Lin, D; Lu, R; Wu, W | 1 |
| Kim, MJ; Kim, YS; Mi Lee, S; Moon, B; Park, HH | 1 |
| Aguilar-Díaz, H; Cossio-Bayugar, R; Mera-Y-Sierra, R; Miranda-Miranda, E; Narváez-Padilla, V; Neira, G; Reynaud, E; Scarcella, S | 1 |
| Brantley, SJ; Chou, TH; Furukawa, H; Lau, AY; Yovanno, RA | 1 |
| Altynbekov, KS; Asadullin, AR; Gayduk, AJ; Khasanova, AK; Markina, EA; Nasyrova, RF; Petrova, MM; Shipulin, GA; Shnayder, NA | 1 |
| Beck, H; Bohmbach, K; Haubrich, AN; Henneberger, C; Hill, K; Masala, N; Opitz, T; Schönhense, EM; Zimmer, A | 1 |
| Ban, Q; Hou, YY; Huang, T; Ma, B; Shi, L; Zhang, ML; Zhang, Q; Zhou, YF | 1 |
| Carlson, M; Choo, TH; De Baun, HM; Dias, E; Gangwisch, J; Girgis, RR; Iosifescu, DV; Kantrowitz, JT; Kegeles, LS; Mayer, MR; Medalia, A; Saperstein, AM; Sehatpour, P; Shope, C; Sobeih, T; Wall, MM | 1 |
| Hepp, R; Tricoire, L | 1 |
| Aryan, F; Calo, E; Jaberi-Lashkari, N; Lee, B | 1 |
| Chorghay, Z; Ghosh, A; Li, VJ; Ruthazer, ES; Schohl, A | 1 |
33 review(s) available for serine and glutamic acid
| Article | Year |
|---|---|
Regulation of enzyme levels by proteolysis: the role of pest regions.
Topics: Amino Acid Sequence; Enzymes; Glutamates; Glutamic Acid; Molecular Sequence Data; Proline; Proteins; Serine; Threonine | 1988 |
Pest sequences in nuclear proteins.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Nuclear Proteins; Proline; Serine; Threonine | 1993 |
Mutagenesis studies of the cardiac Na(+)-Ca2+ exchanger.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Calcium; Carrier Proteins; Dogs; Glutamic Acid; Glycine; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardium; Serine; Sodium; Sodium-Calcium Exchanger; Structure-Activity Relationship; Threonine | 1996 |
PEST sequences and regulation by proteolysis.
Topics: Amino Acid Sequence; Glutamic Acid; Hydrolysis; Molecular Sequence Data; Proline; Proteins; Serine; Threonine | 1996 |
Is all bone the same? Distinctive distributions and properties of non-collagenous matrix proteins in lamellar vs. woven bone imply the existence of different underlying osteogenic mechanisms.
Topics: 1-Carboxyglutamic Acid; Aspartic Acid; Biomechanical Phenomena; Bone and Bones; Bone Diseases; Bone Matrix; Bone Resorption; Chromosome Mapping; Endoplasmic Reticulum; Extracellular Matrix Proteins; Glutamic Acid; Glycoproteins; Humans; Integrin-Binding Sialoprotein; Osteocalcin; Osteoclasts; Osteogenesis; Parathyroid Hormone; Phosphoproteins; Proteins; Sarcoplasmic Reticulum; Serine; Sialoglycoproteins; Time Factors; Tooth | 1998 |
[Glycine therapy of schizophrenia; its rationale and a review of clinical trials].
Topics: Acetamides; Alanine; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Cycloserine; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Humans; Prodrugs; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine | 1998 |
[Endogenous D-serine in mammalian brains].
Topics: Animals; Brain; Glutamic Acid; Glycine; Humans; Racemases and Epimerases; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Spinocerebellar Degenerations; Synaptic Transmission | 2000 |
Atypical neural messengers.
Topics: Animals; Carbon Monoxide; Glutamic Acid; Humans; Neuroglia; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Receptors, N-Methyl-D-Aspartate; Second Messenger Systems; Serine; Synaptic Vesicles; Zinc | 2001 |
Non-equilibrium proteins.
Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Cattle; Glutamic Acid; Humans; Macromolecular Substances; Models, Molecular; Models, Theoretical; Nitric Oxide; Prions; Proline; Protein Conformation; Protein Denaturation; Protein Engineering; Protein Folding; Proteins; Rats; Serine; Structure-Activity Relationship; Threonine | 2001 |
Physiological relevance of endogenous free D-serine in the mammalian brain: are scientists on a royal road for the treatment of glutamatergic-related brain disorders?
Topics: Animals; Astrocytes; Brain Chemistry; Glutamic Acid; Humans; N-Methylaspartate; Neurodegenerative Diseases; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission | 2001 |
Functional neuronal-glial anatomical remodelling in the hypothalamus.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Dehydration; Diffusion; Extracellular Space; Female; gamma-Aminobutyric Acid; Glutamic Acid; Lactation; Neurons; Parturition; Receptors, N-Methyl-D-Aspartate; Serine; Supraoptic Nucleus; Synaptic Transmission | 2006 |
D-serine: a new word in the glutamatergic neuro-glial language.
Topics: Alzheimer Disease; Animals; Astrocytes; Cell Death; Cell Movement; Glutamic Acid; Humans; Neuroglia; Neurons; Neurotransmitter Agents; Schizophrenia; Serine; Synapses; Synaptic Transmission | 2007 |
[Exocytotic release of signaling molecules from astrocytes].
Topics: Adenosine Triphosphate; Animals; Astrocytes; Brain; Calcium; Exocytosis; Glutamic Acid; Humans; Intracellular Signaling Peptides and Proteins; Neurotransmitter Agents; Serine; SNARE Proteins | 2007 |
Regulation of N-methyl-D-aspartate receptors by astrocytic D-serine.
Topics: Animals; Astrocytes; Binding Sites; Brain; Cell Communication; Glutamic Acid; Humans; Ligands; Neurons; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission | 2009 |
Glial cells: indispensable partners of hypothalamic magnocellular neurones.
Topics: Animals; Astrocytes; Glutamic Acid; Hypothalamo-Hypophyseal System; Hypothalamus; Lactation; Neurons; Oxytocin; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Synaptic Transmission | 2009 |
Integrated brain circuits: astrocytic networks modulate neuronal activity and behavior.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Behavior, Animal; Calcium Signaling; Glutamic Acid; Humans; Nerve Net; Nervous System Diseases; Neurons; Neurotransmitter Agents; Purines; Receptors, N-Methyl-D-Aspartate; Serine; Sleep; Synapses; Synaptic Transmission | 2010 |
Do astrocytes really exocytose neurotransmitters?
Topics: Adenosine Triphosphate; Animals; Astrocytes; Cell Death; Electric Conductivity; Exocytosis; Glutamic Acid; Humans; Neurons; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Vesicular Glutamate Transport Proteins | 2010 |
Aberrant control of motoneuronal excitability in amyotrophic lateral sclerosis: excitatory glutamate/D-serine vs. inhibitory glycine/gamma-aminobutanoic acid (GABA).
Topics: Amyotrophic Lateral Sclerosis; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Motor Neurons; Neurotransmitter Agents; Receptors, Glutamate; Serine | 2010 |
Contributions of the D-serine pathway to schizophrenia.
Topics: Animals; Glutamic Acid; Humans; Mice; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Signal Transduction | 2012 |
[Synaptic regulation by astrocytes].
Topics: Adenosine Triphosphate; Animals; Astrocytes; Calcium; Glutamic Acid; Glycogen; Humans; Lactates; Neurons; Neurotransmitter Agents; Pyruvic Acid; Rats; Receptors, Neurotransmitter; Serine; Synaptic Transmission | 2011 |
Analysis of free D-serine in mammals and its biological relevance.
Topics: Animals; Brain; Brain Chemistry; Glutamic Acid; Humans; Mental Disorders; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism | 2011 |
Astrocyte-neuron communication: functional consequences.
Topics: Adenosine Triphosphate; Animals; Astrocytes; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Memory; Neurons; Pain; Respiration; Serine; Sleep; Synaptic Transmission; Wakefulness | 2012 |
Gliotransmission: focus on exocytotic release of L-glutamate and D-serine from astrocytes.
Topics: Animals; Astrocytes; Exocytosis; Glutamic Acid; Humans; Neuroglia; Serine; Synaptic Transmission | 2013 |
D-Serine in neurobiology: CNS neurotransmission and neuromodulation.
Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Central Nervous System; Epilepsy; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Mental Disorders; Neurodegenerative Diseases; Neuronal Plasticity; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission | 2014 |
[Gliaotransmission and brain functions].
Topics: Adenosine Triphosphate; Animals; Astrocytes; Brain; Calcium; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Microglia; Molecular Imaging; Neurons; Neurotransmitter Agents; Receptors, Purinergic P2; Serine; Synapses; Synaptic Transmission | 2015 |
Neuroglial Transmission.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Brain; Cell Communication; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Lactic Acid; Microglia; Neuroglia; Oligodendroglia; Serine; Signal Transduction | 2015 |
Nonessential amino acid metabolism in breast cancer.
Topics: Animals; Arginine; Breast Neoplasms; Cysteine; Diet Therapy; Female; Food Deprivation; Glutamic Acid; Glutamine; Glycine; Humans; Metabolic Networks and Pathways; Proline; Serine | 2016 |
Control of Appetite and Food Preference by NMDA Receptor and Its Co-Agonist d-Serine.
Topics: Appetite; Dopamine; Food Preferences; Glutamic Acid; Humans; Obesity; Receptors, N-Methyl-D-Aspartate; Serine | 2016 |
Body fluid levels of neuroactive amino acids in autism spectrum disorders: a review of the literature.
Topics: Amino Acids; Autism Spectrum Disorder; Body Fluids; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; Humans; Serine; Taurine; Tryptophan | 2017 |
Metabolomics in patients with psychosis: A systematic review.
Topics: 3-Hydroxybutyric Acid; Aspartic Acid; Biomarkers; Bipolar Disorder; Creatine; Female; Glutamic Acid; Glutathione; Humans; Kynurenine; Lactic Acid; Linoleic Acid; Male; Metabolome; Metabolomics; Psychotic Disorders; Schizophrenia; Serine; Tryptophan | 2018 |
d-serine in physiological and pathological brain aging.
Topics: Aging; Alzheimer Disease; Animals; Astrocytes; Cognition; Gene Expression; Glucose; Glutamic Acid; Hippocampus; Humans; Memory; Neuronal Plasticity; Neurons; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Serine | 2021 |
Glycine agonism in ionotropic glutamate receptors.
Topics: Animals; Binding Sites; Glutamic Acid; Glycine; Humans; Ligands; Mice; Receptors, Ionotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission; Xenopus laevis | 2021 |
The Role of D-Serine and D-Aspartate in the Pathogenesis and Therapy of Treatment-Resistant Schizophrenia.
Topics: Aspartic Acid; D-Aspartic Acid; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenia, Treatment-Resistant; Serine | 2022 |
5 trial(s) available for serine and glutamic acid
| Article | Year |
|---|---|
Thiopental and midazolam do not seem to impede metabolism of glutamate in brain-injured patients.
Topics: Adolescent; Adult; Aged; Alanine; Brain Injuries; Cerebral Ventricles; Glutamic Acid; Glutamine; Humans; Hypnotics and Sedatives; Lactates; Midazolam; Middle Aged; Serine; Thiopental | 1999 |
Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma.
Topics: Adenoma; Aged; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Case-Control Studies; Colonic Neoplasms; Female; Genetic Variation; Genotype; Glutamic Acid; Glycine; Haplotypes; Humans; Ibuprofen; Leucine; Lysine; Male; Methionine; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Racemases and Epimerases; Rectal Neoplasms; Serine; Valine | 2007 |
Behavioral and cognitive effects of the N-methyl-D-aspartate receptor co-agonist D-serine in healthy humans: initial findings.
Topics: Adult; Affect; Anxiety; Cognition; Cross-Over Studies; Female; Glutamic Acid; Glycine; Humans; Male; Neuropsychological Tests; Receptors, N-Methyl-D-Aspartate; Serine; Treatment Outcome; Verbal Learning; Young Adult | 2015 |
Effects of Five Amino Acids (Serine, Alanine, Glutamate, Aspartate, and Tyrosine) on Mental Health in Healthy Office Workers: A Randomized, Double-Blind, Placebo-Controlled Exploratory Trial.
Topics: Adult; Aged; Alanine; Amino Acids; Aspartic Acid; Double-Blind Method; Glutamic Acid; Humans; Mental Fatigue; Mental Health; Middle Aged; Occupational Health; Serine; Treatment Outcome; Tyrosine; Young Adult | 2022 |
Dose-Dependent Augmentation of Neuroplasticity-Based Auditory Learning in Schizophrenia: A Double-Blind, Placebo-Controlled, Randomized, Target Engagement Clinical Trial of the NMDA Glutamate Receptor Agonist d-serine.
Topics: Antipsychotic Agents; Double-Blind Method; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; N-Methylaspartate; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine | 2023 |
561 other study(ies) available for serine and glutamic acid
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Prediction of the GTPase activities by using the semiempirical molecular orbital theory.
Topics: Amino Acid Substitution; Chemistry, Physical; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Hydrolysis; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Proto-Oncogene Proteins p21(ras); Thermodynamics | 1998 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
Topics: Amino Acid Motifs; Amino Acid Transport Systems; Aspartic Acid; Binding Sites; Crystallography, X-Ray; Ligands; Models, Molecular; Mutation; Protein Conformation; Protein Subunits; Pyrococcus horikoshii; Sodium; Substrate Specificity; Thermodynamics | 2007 |
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Catalytic Domain; Dipeptides; Gene Expression Regulation, Fungal; Mutagenesis; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction | 2009 |
Substitution of glutamic acid 109 by aspartic acid alters the substrate specificity and catalytic activity of the beta-subunit in the tryptophan synthase bienzyme complex from Salmonella typhimurium.
Topics: Aspartic Acid; Base Sequence; Binding Sites; Catalysis; Glutamates; Glutamic Acid; Hydroxylamines; Molecular Sequence Data; Mutagenesis, Site-Directed; Salmonella typhimurium; Serine; Spectrophotometry; Substrate Specificity; Tryptophan; Tryptophan Synthase | 1992 |
Increased oncogenic potential of ErbB is associated with the loss of a COOH-terminal domain serine phosphorylation site.
Topics: 3T3 Cells; Alanine; Animals; Cell Transformation, Neoplastic; Chick Embryo; Glutamates; Glutamic Acid; Kinetics; Mice; Mutation; Oncogenes; Phosphorylation; Plasmids; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptor, ErbB-2; Serine | 1992 |
Characterization of a full-length, active-site mutant of diphtheria toxin.
Topics: Animals; Binding Sites; Cell Line; Chlorocebus aethiops; Diphtheria Toxin; Glutamates; Glutamic Acid; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Kinetics; Mutagenesis; Osmotic Pressure; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Receptors, Cell Surface; Receptors, Cholinergic; Recombinant Proteins; Serine; Trypsin | 1992 |
Regulation of excitatory amino acid release by N-methyl-D-aspartate receptors in rat striatum: in vivo microdialysis studies.
Topics: Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Dizocilpine Maleate; Extracellular Space; Fluorometry; Glutamates; Glutamic Acid; Kynurenic Acid; Male; N-Methylaspartate; Perfusion; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Serine | 1992 |
An osteonectin-like protein in the matrix of cultured osteogenic cell-line MC3T3-E1, which is associated with calcification.
Topics: Amino Acid Sequence; Animals; Calcification, Physiologic; Cell Line; Collagen; Extracellular Matrix; Glutamates; Glutamic Acid; Glycine; Mice; Molecular Sequence Data; Molecular Weight; Osteoblasts; Osteonectin; Serine | 1992 |
Immunocytochemical and circadian biochemical analysis of neuroactive amino acids in the pineal gland of the rat: effect of superior cervical ganglionectomy.
Topics: Alanine; Analysis of Variance; Animals; Arginine; Aspartic Acid; Chromatography, High Pressure Liquid; Circadian Rhythm; Endothelium; Ganglia, Sympathetic; Ganglionectomy; Glutamates; Glutamic Acid; Glutamine; Immunohistochemistry; Male; Melatonin; Neuroglia; Pineal Gland; Rats; Rats, Sprague-Dawley; Serine; Taurine | 1992 |
Effect of gamma-glutamyl transpeptidase inhibitors on the transport of glutamate into neuronal and glial primary cultures.
Topics: Aging; Animals; Biological Transport; Borates; Brain; Cells, Cultured; Chickens; Diazooxonorleucine; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Kainic Acid; Neuroglia; Neurons; Serine | 1992 |
Limbic seizure-induced changes in extracellular amino acid levels in the hippocampal formation: a microdialysis study of freely moving rats.
Topics: Amino Acids; Amygdala; Animals; Aspartic Acid; Brain Mapping; Chromatography, High Pressure Liquid; Dialysis; Extracellular Space; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kainic Acid; Limbic System; Male; Rats; Rats, Wistar; Seizures; Serine; Synaptic Transmission | 1992 |
Characterization of hematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences.
Topics: Amino Acid Sequence; Animals; Antigens, CD; Base Sequence; Blotting, Northern; Cell Line; Cloning, Molecular; DNA; Glutamates; Glutamic Acid; Hematopoietic Stem Cells; Histocompatibility Antigens; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Leukocyte Common Antigens; Male; Mice; Molecular Sequence Data; Molecular Weight; Oligodeoxyribonucleotides; Organ Specificity; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; RNA; Serine; SH2 Domain-Containing Protein Tyrosine Phosphatases; Substrate Specificity; Threonine | 1992 |
Chemical analysis and scanning electron microscopy of acquired pellicle formed in vivo on stannous fluoride treated enamel.
Topics: Amino Acids; Dental Deposits; Dental Enamel; Dental Pellicle; Glutamates; Glutamic Acid; Glycine; Humans; Microscopy, Electron, Scanning; Serine; Tin Fluorides | 1991 |
Specificity of amino acid transport in renal papilla: microinfusion of Henle's loops and vasa recta.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Glutamates; Glutamic Acid; Kidney Medulla; Kidney Tubules, Distal; Kinetics; Loop of Henle; Male; Models, Biological; Perfusion; Rats; Rats, Inbred Strains; Serine; Taurine | 1991 |
Evidence for heterogenous glycine domains but conserved multiple states of the excitatory amino acid recognition site of the NMDA receptor: regional binding studies with [3H]glycine and [3H]L-glutamate.
Topics: Animals; Autoradiography; Binding, Competitive; Cerebellar Cortex; Cerebral Cortex; Cycloserine; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Kynurenic Acid; Ligands; Male; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Serine | 1991 |
Amino acid composition of acquired enamel pellicle collected in vivo after 2 hours and after 24 hours.
Topics: Amino Acids; Dental Deposits; Dental Enamel; Dental Pellicle; Diet; Fasting; Glutamates; Glutamic Acid; Glycine; Humans; Proline; Serine; Time Factors | 1991 |
Presence of the HNK-1 epitope (3-sulfoglucuronic acid) on oligosaccharides from squid skin chondroitin proteoglycans and degradation of proteoglycans by proteolytic enzymes.
Topics: Animals; Antigens, Differentiation; CD57 Antigens; Chondroitin; Decapodiformes; Endopeptidases; Enzyme-Linked Immunosorbent Assay; Epitopes; Glucuronates; Glutamates; Glutamic Acid; Glycine; Microbial Collagenase; Oligosaccharides; Proteoglycans; Serine; Skin | 1991 |
Plasminogen activation with single-chain urokinase-type plasminogen activator (scu-PA). Studies with active site mutagenized plasminogen (Ser740----Ala) and plasmin-resistant scu-PA (Lys158----Glu).
Topics: Alanine; Enzyme Activation; Enzyme Precursors; Escherichia coli; Fibrinolysin; Glutamates; Glutamic Acid; Humans; Kinetics; Lysine; Mutation; Plasminogen; Plasminogen Activators; Recombinant Proteins; Serine; Urokinase-Type Plasminogen Activator | 1990 |
High-performance liquid chromatographic determination of selected amino acids in rat brain by precolumn derivatization with phenylisothiocyanate.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Isothiocyanates; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Thiocyanates | 1990 |
Deamidation of glutamine by increased plasma gamma-glutamyltransferase is a source of rapid ammonia formation in blood and plasma specimens.
Topics: Ammonia; Borates; Chromatography, Gel; Diazooxonorleucine; False Positive Reactions; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Glutaminase; Glutamine; Humans; Maleates; Serine; Specimen Handling | 1990 |
Renal arginine synthesis: studies in vitro and in vivo.
Topics: Alanine; Ammonium Chloride; Animals; Arginine; Aspartic Acid; Citrulline; Glomerular Filtration Rate; Glutamates; Glutamic Acid; Glutamine; Glycine; In Vitro Techniques; Kidney Cortex; Kidney Tubules; Kinetics; Male; Rats; Rats, Inbred Strains; Serine | 1990 |
Stimulatory actions of bioflavonoids on tyrosine uptake into cultured bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Biological Transport; Carbon Radioisotopes; Catecholamines; Cattle; Cells, Cultured; Chamomile; Flavones; Flavonoids; Glutamates; Glutamic Acid; Histidine; Lysine; Oils, Volatile; Plants, Medicinal; Quercetin; Serine; Tyrosine | 1990 |
Pest sequences present in the subunits of phosphorylase kinase.
Topics: Amino Acid Sequence; Animals; Glutamates; Glutamic Acid; Humans; Molecular Sequence Data; Muscles; Phosphorylase Kinase; Proline; Rabbits; Serine; Threonine | 1990 |
Active-site mutations of diphtheria toxin: effects of replacing glutamic acid-148 with aspartic acid, glutamine, or serine.
Topics: Adenosine Diphosphate Ribose; Affinity Labels; Aspartic Acid; Base Sequence; Binding Sites; Diphtheria Toxin; Glutamates; Glutamic Acid; Glutamine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Serine; Substrate Specificity | 1990 |
Isolation and properties of sea turtle (Chelonia mydas) pituitary prolactin.
Topics: Amino Acids; Animals; Aspartic Acid; Disulfides; Electrophoresis, Polyacrylamide Gel; Epitopes; Glutamates; Glutamic Acid; Humans; Leucine; Pituitary Gland; Prolactin; Radioimmunoassay; Serine; Species Specificity; Turtles | 1985 |
Effect of impact trauma on neurotransmitter and nonneurotransmitter amino acids in rat spinal cord.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kinetics; Laminectomy; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Serine; Spinal Cord; Spinal Cord Injuries; Taurine; Threonine | 1989 |
Kinetic and magnetic resonance studies of the glutamate-43 to serine mutant of staphylococcal nuclease.
Topics: Cations, Divalent; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Micrococcal Nuclease; Models, Theoretical; Mutation; Protein Binding; Serine | 1989 |
Characterization of amino acid transport in membrane vesicles from the thermophilic fermentative bacterium Clostridium fervidus.
Topics: Amino Acids; Biological Transport; Cell Membrane; Clostridium; Fermentation; Glutamates; Glutamic Acid; Kinetics; Membrane Fusion; Membrane Potentials; Serine; Sodium Channels; Temperature | 1989 |
Variation in G + C-content and codon choice: differences among synonymous codon groups in vertebrate genes.
Topics: Animals; Arginine; Base Composition; Cattle; Chickens; Codon; Glutamates; Glutamic Acid; Humans; Leucine; Mice; Phenylalanine; Rats; Regression Analysis; RNA, Messenger; Serine; Species Specificity | 1989 |
beta-Amyloid precursor is a PEST protein.
Topics: Amino Acid Sequence; Amyloid; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Brain Chemistry; Calpain; Glutamates; Glutamic Acid; Molecular Sequence Data; Proline; Protease Inhibitors; Protein Precursors; Rats; Serine; Threonine | 1989 |
Substitution of amino acids in helix F of bacteriorhodopsin: effects on the photochemical cycle.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Bacteriorhodopsins; Glutamates; Glutamic Acid; Glutamine; Glycine; Hydrogen Bonding; Kinetics; Leucine; Molecular Sequence Data; Mutation; Phenylalanine; Photochemistry; Proline; Protons; Serine; Tryptophan | 1989 |
Splanchnic substrate balance in malnourished patients during parenteral nutrition.
Topics: Adipose Tissue; Alanine; Amino Acids, Branched-Chain; Cystine; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycine; Humans; Lipids; Liver; Male; Mesentery; Nitrogen; Parenteral Nutrition; Parenteral Nutrition, Total; Protein Biosynthesis; Protein-Energy Malnutrition; Serine; Splanchnic Circulation; Threonine; Tyrosine | 1985 |
Isolation and characterization of a kappa amyloid fibril protein.
Topics: Amino Acid Sequence; Amyloid; Amyloidosis; Animals; Antibody Formation; Electrophoresis, Polyacrylamide Gel; Female; Glutamates; Glutamic Acid; Histidine; Humans; Immunodiffusion; Isoleucine; Methionine; Middle Aged; Rabbits; Serine | 1985 |
Serine synthesis by an isolated perfused rat kidney preparation.
Topics: Amino Acids; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Glycerol; Kidney; Male; Perfusion; Picolinic Acids; Rats; Rats, Inbred Strains; Serine | 1985 |
Maternal undernutrition during lactation: effect on amino acids in brain regions of offspring.
Topics: Amino Acids; Animals; Aspartic Acid; Body Weight; Brain Chemistry; Corpus Striatum; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Hippocampus; Hypothalamus; Lactation; Nutrition Disorders; Pregnancy; Rats; Rats, Inbred Strains; Serine; Taurine | 1985 |
The characterization of the specific binding of [3H]-N-acetylaspartylglutamate to rat brain membranes.
Topics: Animals; Binding, Competitive; Brain; Calcium; Dipeptides; Glutamates; Glutamic Acid; Guanine Nucleotides; Ibotenic Acid; Kinetics; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Serine; Sodium; Synaptosomes; Tissue Distribution | 1985 |
Isolation of serine, glutamic acid, and glycine-rich nonhistone proteins from bovine cerebral cortex.
Topics: Amino Acids; Animals; Cattle; Cerebral Cortex; Chromosomal Proteins, Non-Histone; Electrophoresis, Polyacrylamide Gel; Glutamates; Glutamic Acid; Glycine; Serine | 1985 |
Differential changes in the content of amino acid neurotransmitters in discrete regions of the rat brain prior to the onset and during the course of homocysteine-induced seizures.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Corpus Striatum; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Hippocampus; Homocysteine; Hypothalamus; Inferior Colliculi; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Substantia Nigra; Taurine; Tissue Distribution | 1986 |
Glutamic acid as a putative transmitter of the interhemispheric corticocortical connections in the rat.
Topics: Alanine; Animals; Aspartic Acid; Brain Chemistry; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Male; Rats; Rats, Inbred Strains; Serine; Threonine | 1986 |
Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis.
Topics: Amino Acid Sequence; Caseins; Glutamates; Glutamic Acid; Half-Life; HeLa Cells; Humans; Proline; Proteins; Serine; Threonine | 1986 |
Huntington's disease: studies on brain free amino acids.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Aspartic Acid; Brain; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Histidine; Humans; Huntington Disease; Lysine; Male; Middle Aged; Putamen; Serine; Taurine | 1988 |
Construction of an altered proton donation mechanism in Escherichia coli dihydrofolate reductase.
Topics: Escherichia coli; Genes; Genes, Bacterial; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Mathematics; Methotrexate; Mutation; Protein Binding; Protons; Serine; Tetrahydrofolate Dehydrogenase | 1987 |
Mutagenesis of the alpha subunit of the F1Fo-ATPase from Escherichia coli. Mutations at Glu-196, Pro-190, and Ser-199.
Topics: Amino Acid Sequence; Escherichia coli; Glutamates; Glutamic Acid; Kinetics; Macromolecular Substances; Molecular Sequence Data; Mutation; Plasmids; Proline; Protein Conformation; Proton-Translocating ATPases; Serine; Spectrometry, Fluorescence | 1988 |
The amino acid sequence of bovine thymus prothymosin alpha.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Cattle; Glutamates; Glutamic Acid; Humans; Molecular Sequence Data; Peptide Fragments; Protein Precursors; Rats; Serine; Species Specificity; Thymosin; Thymus Gland | 1988 |
Phosphorylation of phosvitin by casein kinase-2 provides the evidence that phosphoserines can replace carboxylic amino acids as specificity determinants.
Topics: Amino Acids; Aspartic Acid; Casein Kinases; Egg Proteins; Glutamates; Glutamic Acid; Phosphorylation; Phosphoserine; Phosphothreonine; Phosvitin; Protein Kinases; Serine; Substrate Specificity | 1988 |
Effect of inhibitors of gamma-glutamyl transpeptidase on the uptake of glutamate and aspartate into cultured astroglial cells from the glycogen body and cerebral hemispheres of the embryonic chick.
Topics: Animals; Aspartic Acid; Astrocytes; Biological Transport; Borates; Brain; Cells, Cultured; Chick Embryo; Diazooxonorleucine; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Kainic Acid; Serine; Spinal Cord | 1988 |
Structural and functional integrity of specificity and catalytic sites of trypsin.
Topics: Aspartic Acid; Binding Sites; Escherichia coli; Glutamates; Glutamic Acid; Kinetics; Models, Theoretical; Serine; Trypsin; Trypsinogen | 1988 |
Production of hemolysin by Vibrio parahaemolyticus in a chemically defined medium.
Topics: Culture Media; Glutamates; Glutamic Acid; Hemolysin Proteins; Hot Temperature; Serine; Vibrio parahaemolyticus | 1981 |
Effect of amino acids on microbial production of citric acid by Aspergillus niger.
Topics: Amino Acids; Aspartic Acid; Aspergillus niger; Citrates; Citric Acid; Cysteine; Glutamates; Glutamic Acid; Lysine; Serine | 1982 |
On the uptake of nystatin by saccharomyces cerevisiae. 5 The release of amino acids.
Topics: Alanine; Amino Acids; Calcium; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Nystatin; Saccharomyces cerevisiae; Serine; Sterols; Temperature | 1982 |
Glutamate uptake into cerebral cortex slices is reduced in the presence of a gamma-glutamyl transpeptidase inhibitor.
Topics: Aging; Animals; Biological Transport, Active; Borates; Cerebral Cortex; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Serine; Sodium | 1983 |
Effects of some putative amino acid neurotransmitters on the stimulated TSH secretion in male rats.
Topics: Amino Acids; Animals; Cold Temperature; Glutamates; Glutamic Acid; Glycine; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Thyrotropin; Time Factors | 1983 |
Intermediary metabolism in Legionella pneumophila: utilization of amino acids and other compounds as energy sources.
Topics: Acetates; Amino Acids; Carboxylic Acids; Glucose; Glutamates; Glutamic Acid; Lactates; Lactic Acid; Legionella; Oxygen Consumption; Pentosephosphates; Pyruvates; Pyruvic Acid; Serine; Threonine | 1983 |
Pathways of L-glutamic acid transport in cultured human fibroblasts.
Topics: Aminoisobutyric Acids; Aspartic Acid; Biological Transport; Cell Count; Cells, Cultured; Fibroblasts; Glutamates; Glutamic Acid; Humans; Kinetics; Serine; Sodium | 1983 |
Effects of a nonspecific nitrogen deficiency on growth rate and leg problems in chicks.
Topics: Amino Acids, Essential; Animals; Body Weight; Bone Diseases, Metabolic; Chickens; Glutamates; Glutamic Acid; Glycine; Male; Nitrogen; Nutritional Requirements; Poultry Diseases; Serine; Stereoisomerism | 1984 |
Study of the relationship between free amino acids and cataract in human lenses.
Topics: Adult; Aged; Alanine; Amino Acids; Cataract; Glutamates; Glutamic Acid; Glycine; Humans; Lens, Crystalline; Leucine; Middle Aged; Serine; Threonine | 1984 |
Symmetrical distribution of amino acid neurotransmitters in the right and left cerebral cortex of the rat.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Glycine; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Threonine; Tissue Distribution | 1984 |
Regulation of net amino acid exchange in sea urchin larvae.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Glycine; Larva; Sea Urchins; Serine; Time Factors | 1984 |
Decreased cysteine and proline synthesis in parenterally fed, premature infants.
Topics: Alanine; Amino Acids; Aspartic Acid; Birth Weight; Blood Glucose; Carbon Isotopes; Cysteine; Electrolytes; Energy Intake; Female; Food, Formulated; Gas Chromatography-Mass Spectrometry; Gestational Age; Glucose; Glutamic Acid; Glycine; Humans; Infant Food; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Lipids; Male; Parenteral Nutrition; Parenteral Nutrition Solutions; Proline; Serine; Solutions | 1995 |
Mutation of serine 90 to glutamic acid mimics phosphorylation of bovine prolactin.
Topics: Amino Acid Sequence; Animals; Biological Assay; Cattle; Circular Dichroism; Glutamic Acid; Lymphoma; Mutagenesis, Site-Directed; Phosphoproteins; Phosphorylation; Point Mutation; Prolactin; Protein Conformation; Rats; Recombinant Proteins; Serine; Spectrometry, Fluorescence | 1995 |
Traumatic brain injury-induced excitotoxicity assessed in a controlled cortical impact model.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Brain; Brain Injuries; Cerebral Cortex; Glutamates; Glutamic Acid; Glutamine; Male; Microdialysis; Microinjections; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Serine | 1993 |
NMDA receptor channels: subunit-specific potentiation by reducing agents.
Topics: Alanine; Animals; Base Sequence; Cell Line; Cloning, Molecular; Cysteine; Dithiothreitol; Drug Synergism; Ethylmaleimide; Glutamates; Glutamic Acid; Glutathione; Humans; Ion Channels; Kidney; Kinetics; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Serine; Transfection | 1994 |
A cyclin-dependent kinase homologue, p130PITSLRE is a phosphotyrosine-independent SH2 ligand.
Topics: Amino Acid Sequence; Animals; Base Sequence; Casein Kinases; Cell Line; Chromatography, Affinity; Cloning, Molecular; DNA, Complementary; Glutamic Acid; Humans; Ligands; Mice; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins pp60(c-src); RNA; Sequence Homology, Amino Acid; Serine; Tyrosine | 1994 |
Modification of Ser59 in the unique N-terminal region of tyrosine kinase p56lck regulates specificity of its Src homology 2 domain.
Topics: Amino Acid Sequence; Glutamic Acid; Glutathione Transferase; HeLa Cells; Humans; Kinetics; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Oncogene Proteins, Viral; Phosphopeptides; Phosphorylation; Point Mutation; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Substrate Specificity; T-Lymphocytes | 1995 |
Alteration of [3H]MK-801 binding associated with the N-methyl-D-Aspartate receptor complex by acute ethanol in rat cortex and hippocampus in vitro.
Topics: Animals; Cerebral Cortex; Culture Techniques; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ethanol; Glutamic Acid; Glycine; Hippocampus; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Serine; Synaptic Membranes; Synaptic Transmission | 1995 |
Isolation and partial characterization of rat sperm tail fibrous sheath proteins and comparison with rabbit and human spermatozoa using a polyclonal antiserum.
Topics: Animals; Aspartic Acid; Blotting, Western; Cystine; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Glutamic Acid; Glycine; Humans; Immune Sera; Leucine; Male; Microscopy, Electron; Proteins; Rabbits; Rats; Rats, Sprague-Dawley; Serine; Sperm Tail | 1995 |
Extracellular concentration of endogenous free D-serine in the rat brain as revealed by in vivo microdialysis.
Topics: Amino Acids; Animals; Brain; Cerebellum; Corpus Striatum; Extracellular Space; Glutamic Acid; Glycine; Kinetics; Male; Microdialysis; Organ Specificity; Prefrontal Cortex; Rats; Rats, Wistar; Serine; Sodium Channel Blockers; Stereoisomerism; Tetrodotoxin; Veratrine | 1995 |
Induction of cystine transport activity in mouse peritoneal macrophages by bacterial lipopolysaccharide.
Topics: Amino Acids; Animals; Biological Transport; Cells, Cultured; Cystine; Dose-Response Relationship, Drug; Female; Glutamic Acid; Glutathione; Homocysteine; Interferon-gamma; Interleukin-1; Kinetics; Lipopolysaccharides; Macrophages, Peritoneal; Maleates; Mice; Mice, Inbred C57BL; Recombinant Proteins; Salmonella typhi; Serine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 1995 |
Some observations on the nutritional requirements of Eikenella corrodens ATCC 23834T grown in continuous culture.
Topics: Amino Acids; Cell Division; Culture Media; Eikenella corrodens; Glutamic Acid; Hydrogen-Ion Concentration; Nitrates; Serine; Time Factors | 1995 |
Structure-function analysis of the ion channel selectivity filter in human annexin V.
Topics: Annexin A5; Binding Sites; Calcium; Computer Graphics; Crystallography, X-Ray; Electric Conductivity; Glutamates; Glutamic Acid; Humans; Ion Channels; Microscopy, Electron; Mutagenesis, Site-Directed; Potassium; Protein Structure, Secondary; Serine; Sodium; Structure-Activity Relationship | 1993 |
Structural determinants of allosteric regulation in alternatively spliced AMPA receptors.
Topics: Allosteric Regulation; Alternative Splicing; Amino Acid Sequence; Animals; Benzothiadiazines; Embryo, Mammalian; Embryo, Nonmammalian; Glutamic Acid; Glutamine; Humans; Kainic Acid; Kidney; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Point Mutation; Receptors, AMPA; Receptors, Kainic Acid; Serine; Transfection; Xenopus laevis | 1995 |
D-serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release.
Topics: Animals; Antibody Specificity; Astrocytes; Autoradiography; Brain; Cells, Cultured; D-Amino-Acid Oxidase; Glutamic Acid; Hippocampus; Immunohistochemistry; Kainic Acid; Models, Neurological; Organ Specificity; Rats; Serine; Stereoisomerism; Synapses; Telencephalon; Tritium | 1995 |
Time-related cortical amino acid changes after basal forebrain lesion: a microdialysis study.
Topics: Alzheimer Disease; Amino Acids; Animals; Brain Diseases; Cerebral Cortex; Chromatography, High Pressure Liquid; Fluorescence; Glutamic Acid; Glycine; Ibotenic Acid; Male; Microdialysis; Potassium; Rats; Rats, Sprague-Dawley; Serine; Taurine; Time Factors | 1995 |
Binding of high-molecular-mass kininogen to the Apple 1 domain of factor XI is mediated in part by Val64 and Ile77.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Computer Simulation; Factor XI; Glutamic Acid; Humans; Isoleucine; Kininogens; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding; Protein Conformation; Recombinant Proteins; Serine; Valine | 1994 |
Effects of memantine on synaptic transmission in the hippocampus in vitro.
Topics: Animals; Electric Stimulation; Glutamic Acid; Hippocampus; In Vitro Techniques; Interneurons; Long-Term Potentiation; Male; Memantine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Serine; Synapses; Synaptic Transmission; Theta Rhythm | 1995 |
Cystine uptake and glutathione level in fetal brain cells in primary culture and in suspension.
Topics: Animals; beta-Alanine; Biological Transport; Brain; Cells, Cultured; Cysteine; Cystine; Female; Fetus; Glutamates; Glutamic Acid; Glutathione; In Vitro Techniques; Kinetics; Neurons; Pregnancy; Rats; Rats, Wistar; Serine; Sodium; Time Factors | 1993 |
Cleavage at site A, Glu-642 to Ser-643, of the gizzard myosin heavy chain decreases affinity for actin.
Topics: Actins; Amino Acid Sequence; Animals; Electrophoresis, Polyacrylamide Gel; Gizzard, Avian; Glutamates; Glutamic Acid; Kinetics; Metalloendopeptidases; Molecular Sequence Data; Muscle, Smooth; Myosin Subfragments; Myosins; Papain; Peptide Fragments; Serine; Substrate Specificity; Turkeys | 1993 |
Effects of diet-induced hyperthreoninemia. II). Tissue and extracellular amino acid levels in the brain.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Cerebral Cortex; Diet; Glutamates; Glutamic Acid; Glycine; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord; Threonine | 1994 |
rho GAP of 28 kDa (GAP2), but not of 190 kDa (p190), requires Asp65 and Asp67 of rho GTPase for its activation.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Enzyme Activation; Glutamates; Glutamic Acid; GTP Phosphohydrolases; GTPase-Activating Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Molecular Sequence Data; Mutation; Proteins; ras GTPase-Activating Proteins; Rats; Rho Factor; Sequence Homology, Amino Acid; Serine | 1993 |
Electrostatic activation of rat phenylalanine hydroxylase.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Cyclic AMP-Dependent Protein Kinases; DNA; Electrochemistry; Enzyme Activation; Glutamates; Glutamic Acid; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine Hydroxylase; Phosphorylation; Plasmids; Polymerase Chain Reaction; Rats; Recombinant Proteins; Restriction Mapping; Serine | 1994 |
Release of glutamate and aspartate from the preoptic area during the progesterone-induced LH surge: in vivo microdialysis studies.
Topics: Animals; Aspartic Acid; Estradiol; Feedback; Female; Follicle Stimulating Hormone; Glutamates; Glutamic Acid; Luteinizing Hormone; Microdialysis; Ovariectomy; Preoptic Area; Progesterone; Rats; Rats, Sprague-Dawley; Serine | 1994 |
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells.
Topics: 3T3 Cells; Alanine; Animals; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Neoplastic; Culture Media, Serum-Free; DNA; Enzyme Activation; Glutamates; Glutamic Acid; Mice; Mitogen-Activated Protein Kinase Kinases; Mutation; Neurites; Neurons; PC12 Cells; Protein Kinase Inhibitors; Protein Kinases; Serine; Signal Transduction | 1994 |
Dietary pectin's effect on ileal and fecal amino acid digestibility and exocrine pancreatic secretions in growing pigs.
Topics: alpha-Amylases; Amino Acids; Animals; Aspartic Acid; Dietary Fiber; Digestion; Feces; Glutamates; Glutamic Acid; Glycine; Ileum; Male; Pancreas; Pancreatic Juice; Pectins; Phenylalanine; Proline; Serine; Swine; Threonine; Trypsin; Valine | 1994 |
Dextrorphan inhibits the release of excitatory amino acids during spinal cord ischemia.
Topics: Amino Acids; Animals; Aspartic Acid; Dextrorphan; Evoked Potentials; Evoked Potentials, Somatosensory; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ischemia; Microdialysis; Motor Cortex; Neurotransmitter Agents; Receptors, Amino Acid; Serine; Spinal Cord; Swine | 1994 |
An assessment of progression of brain edema with amino acid levels in cerebrospinal fluid and changes in electroencephalogram in an adult cat model of cold brain injury.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cats; Electroencephalography; Evoked Potentials; Freezing; Glutamic Acid; Methionine; Motor Cortex; Phenylalanine; Serine; Synaptic Transmission; Tyrosine; Valine | 1994 |
Physiological role of nhaB, a specific Na+/H+ antiporter in Escherichia coli.
Topics: Carrier Proteins; DNA Restriction Enzymes; Escherichia coli; Genes, Bacterial; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Lithium; Mutagenesis; Plasmids; Potassium; Proline; Serine; Sodium; Sodium-Hydrogen Exchangers | 1993 |
Phosphorylation and modulation of recombinant GluR6 glutamate receptors by cAMP-dependent protein kinase.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Line; Cyclic AMP; Embryo, Mammalian; Glutamates; Glutamic Acid; Humans; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinases; Rats; Receptors, Glutamate; Recombinant Proteins; Serine; Transfection | 1993 |
Alteration of the enzymatic specificity of human angiogenin by site-directed mutagenesis.
Topics: Angiogenesis Inducing Agents; Animals; Base Sequence; Chick Embryo; Glutamates; Glutamic Acid; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotides; Proteins; Ribonuclease, Pancreatic; Serine; Substrate Specificity; Threonine | 1993 |
An evaluation of the role of extracellular amino acids in the delayed neurodegeneration induced by quinolinic acid in the rat striatum.
Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Corpus Striatum; Dialysis; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Male; Microinjections; Nerve Degeneration; Niacin; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Serine; Threonine | 1993 |
Amino acid transport in the thermophilic anaerobe Clostridium fervidus is driven by an electrochemical sodium gradient.
Topics: Amino Acids; Arginine; Bacteria, Anaerobic; Biological Transport, Active; Cations; Clostridium; Diffusion; Dose-Response Relationship, Drug; Electron Transport Complex IV; Glutamates; Glutamic Acid; Hot Temperature; Kinetics; Liposomes; Membrane Potentials; Membranes; Serine; Sodium | 1993 |
Serine released from hippocampal slices during deprivation of oxygen and glucose enhances the effects of glutamate on neuronal function.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Dizocilpine Maleate; Glucose; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; Hypoxia; In Vitro Techniques; Kynurenic Acid; Neurons; Phosphocreatine; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission | 1993 |
Mechanism of the enhanced intrinsic activity of single-chain urokinase-type plasminogen activator during ongoing fibrinolysis.
Topics: Alanine; Binding Sites; Catalysis; Cell Line; Enzyme Activation; Fibrin; Fibrinolysis; Glutamates; Glutamic Acid; Humans; Kinetics; Lysine; Mutagenesis, Site-Directed; Plasminogen; Plasminogen Activator Inhibitor 1; Recombinant Proteins; Serine; Solutions; Urokinase-Type Plasminogen Activator | 1993 |
A difference in the sequence of steps in the reactions catalyzed by two closely homologous forms of glutamate dehydrogenase.
Topics: Animals; Aspartic Acid; Binding Sites; Cattle; Clostridium; Glutamate Dehydrogenase; Glutamic Acid; Kinetics; Liver; Lysine; Protein Binding; Serine; Time Factors | 1996 |
Pest sequences in EF-hand calcium-binding proteins.
Topics: Amino Acid Sequence; Calcium-Binding Proteins; Glutamic Acid; Helix-Loop-Helix Motifs; Molecular Sequence Data; Multigene Family; Proline; S100 Proteins; Serine; Threonine | 1995 |
E5 oncoprotein transmembrane mutants dissociate fibroblast transforming activity from 16-kilodalton protein binding and platelet-derived growth factor receptor binding and phosphorylation.
Topics: 3T3 Cells; Adenosine Triphosphatases; Amino Acid Sequence; Animals; Base Sequence; Cell Transformation, Viral; Glutamic Acid; Golgi Apparatus; Hematopoietic Stem Cells; Lysine; Mice; Molecular Sequence Data; Oncogene Proteins, Viral; Phosphorylation; Point Mutation; Protein Binding; Receptors, Platelet-Derived Growth Factor; Serine | 1996 |
Activation of hepatic acetyl-CoA carboxylase by glutamate and Mg2+ is mediated by protein phosphatase-2A.
Topics: Acetyl-CoA Carboxylase; Amino Acid Sequence; AMP-Activated Protein Kinases; Animals; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Enzyme Activation; Female; Glutamic Acid; Humans; Isoenzymes; Kinetics; Liver; Magnesium; Molecular Sequence Data; Multienzyme Complexes; Muscle, Skeletal; Peptide Fragments; Phosphoprotein Phosphatases; Protein Kinases; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Sequence Homology, Amino Acid; Serine; Substrate Specificity | 1996 |
Acute and repeated systemic amphetamine administration: effects on extracellular glutamate, aspartate, and serine levels in rat ventral tegmental area and nucleus accumbens.
Topics: Amino Acids; Amphetamine; Animals; Aspartic Acid; Calcium; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Extracellular Space; Glutamic Acid; Male; Microdialysis; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Serine; Time Factors; Ventral Tegmental Area | 1996 |
Differentiation of catalytic sites on Escherichia coli F1ATPase by laser photoactivated labeling with [3H]-2-Azido-ATP using the mutant beta Glu381Cys:epsilonSer108Cys to identify different beta subunits by their interactions with gamma and epsilon subuni
Topics: Adenosine Triphosphate; Affinity Labels; Azides; Cysteine; Edetic Acid; Escherichia coli; Glutamic Acid; Kinetics; Macromolecular Substances; Magnesium; Mutagenesis, Site-Directed; Photolysis; Point Mutation; Protein Binding; Proton-Translocating ATPases; Recombinant Proteins; Serine; Spectrometry, Fluorescence; Tritium | 1996 |
Ligand binding to integrin alphaIIbbeta3 is dependent on a MIDAS-like domain in the beta3 subunit.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Glutamic Acid; Humans; Mice; Molecular Sequence Data; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine | 1996 |
Changes in the intracellular free amino acid pool in human saphenous vein tissue culture.
Topics: Aged; Alanine; Amino Acids; Asparagine; Aspartic Acid; Culture Techniques; Cytosol; Glutamic Acid; Glutamine; Glycine; Humans; Middle Aged; Proline; Saphenous Vein; Serine; Taurine | 1996 |
Amino-acid-dependent modulation of amino acid transport in Xenopus laevis oocytes.
Topics: Amino Acid Transport Systems; Amino Acids; Animals; Arginine; Biological Transport; Carrier Proteins; Female; Glutamic Acid; Glutamine; Glycine; Oocytes; Phenylalanine; Serine; Sodium; Xenopus laevis | 1996 |
Properties of synthetic analogs of gramicidin S containing L-serine or L-glutamic acid residue in place of L-ornithine residue.
Topics: Glutamic Acid; Gramicidin; Ornithine; Serine | 1996 |
Expression and characterization of glycogen synthase kinase-3 mutants and their effect on glycogen synthase activity in intact cells.
Topics: Alanine; Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cloning, Molecular; DNA Primers; Escherichia coli; Glutamic Acid; Glycogen Synthase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Kidney; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Rabbits; Recombinant Proteins; Serine; Transfection | 1996 |
Altered responsiveness of medullary depressor neurones to L-glutamate and D-serine in SHR rats.
Topics: Animals; Blood Pressure; Glutamic Acid; Hypertension; Kynurenic Acid; Medulla Oblongata; Microinjections; Neurons; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Glycine; Serine; Stereoisomerism | 1996 |
Two amino acid differences in the sixth transmembrane domain are partially responsible for the pharmacological differences between the 5-HT1D beta and 5-HT1E 5-hydroxytryptamine receptors.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Binding, Competitive; Chlorocebus aethiops; Cloning, Molecular; COS Cells; DNA Primers; Ergolines; Glutamic Acid; Humans; Isoleucine; Kinetics; Ligands; Lysine; Models, Structural; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Protein Structure, Secondary; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Serotonin; Transfection | 1996 |
Additivity of apparent and true ileal amino acid digestibilities in soybean meal, sunflower meal, and meat and bone meal for broilers.
Topics: Amino Acids; Analysis of Variance; Animals; Aspartic Acid; Biological Products; Chickens; Digestion; Female; Glutamic Acid; Glycine max; Helianthus; Homoarginine; Ileum; Isoleucine; Meat; Minerals; Predictive Value of Tests; Serine; Tyrosine | 1996 |
In vivo elevation of extracellular potassium in the rat amygdala increases extracellular glutamate and aspartate and damages neurons.
Topics: Amygdala; Animals; Aspartic Acid; Brain Edema; Extracellular Space; Glutamic Acid; Glutamine; Glycine; Kinetics; Male; Microdialysis; Neurons; Potassium; Potassium Chloride; Rats; Rats, Wistar; Serine; Taurine | 1996 |
Some considerations regarding the use of amino acid racemization in human dentine as an indicator of age at death.
Topics: Age Determination by Teeth; Amino Acids; Aspartic Acid; Calibration; Chromatography, High Pressure Liquid; Collagen; Dentin; Forensic Anthropology; Glutamic Acid; History, 19th Century; History, Ancient; History, Modern 1601-; Humans; Linear Models; Racemases and Epimerases; Serine | 1997 |
Neurochemical changes in cerebellum of goldfish exposed to various temperatures.
Topics: Acclimatization; Adenine Nucleotides; Adenosine; Alanine; Animals; Aspartic Acid; Cerebellum; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Goldfish; Kinetics; Potassium; Serine; Taurine; Temperature | 1997 |
Modulation of bovine papillomavirus DNA replication by phosphorylation of the viral E1 protein.
Topics: Adenosine Triphosphatases; Alanine; Animals; Binding Sites; Bovine papillomavirus 1; Cattle; Cell Line; CHO Cells; Cricetinae; DNA Helicases; DNA Replication; DNA-Binding Proteins; DNA, Viral; Genome, Viral; Glutamic Acid; Mice; Mutagenesis; Phosphorylation; Recombinant Fusion Proteins; Replication Origin; Serine; Spodoptera; Tumor Cells, Cultured; Viral Proteins; Virus Replication | 1997 |
Substrate recognition of isocitrate dehydrogenase and 3-isopropylmalate dehydrogenase from Thermus thermophilus HB8.
Topics: 3-Isopropylmalate Dehydrogenase; Alcohol Oxidoreductases; Amino Acid Sequence; Asparagine; Aspartic Acid; Binding Sites; Glutamic Acid; Isocitrate Dehydrogenase; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Serine; Substrate Specificity; Thermus thermophilus | 1997 |
Amino acid concentrations in hypothalamic and caudate nuclei during microwave-induced thermal stress: analysis by microdialysis.
Topics: Amino Acids; Animals; Aspartic Acid; Body Temperature; Caudate Nucleus; Chromatography, High Pressure Liquid; Electromagnetic Fields; Functional Laterality; Glutamic Acid; Glutamine; Glycine; Hot Temperature; Hypothalamus; Male; Microdialysis; Microwaves; Rats; Rats, Sprague-Dawley; Serine; Skin Temperature; Stress, Physiological; Time Factors | 1997 |
Bcl-2 phosphorylation required for anti-apoptosis function.
Topics: Alanine; Animals; Apoptosis; Bryostatins; Cell Line; Dimerization; Enzyme Activation; Etoposide; Glutamic Acid; Interleukin-3; Kinetics; Lactones; Macrolides; Mice; Mutagenesis, Site-Directed; Phosphates; Phosphorylation; Point Mutation; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Serine; Transfection | 1997 |
Temperature dependency of basal and evoked release of amino acids and calcitonin gene-related peptide from rat dorsal spinal cord.
Topics: Animals; Aspartic Acid; Body Temperature; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Chromatography, High Pressure Liquid; Cross Reactions; Fever; Glutamic Acid; Glycine; Hypothermia; Male; Organ Culture Techniques; Potassium; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord; Synaptic Transmission | 1997 |
A single serine residue at position 375 of VP16 is critical for complex assembly with Oct-1 and HCF and is a target of phosphorylation by casein kinase II.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Casein Kinase II; Consensus Sequence; COS Cells; DNA-Binding Proteins; Glutamic Acid; HeLa Cells; Herpes Simplex Virus Protein Vmw65; Host Cell Factor C1; Humans; Macromolecular Substances; Molecular Sequence Data; Octamer Transcription Factor-1; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Threonine; Transcription Factors; Transcriptional Activation | 1997 |
Design of a leucine zipper coiled coil stabilized 1.4 kcal mol-1 by phosphorylation of a serine in the e position.
Topics: Amino Acid Sequence; Arginine; Avian Proteins; Basic-Leucine Zipper Transcription Factors; Carrier Proteins; Centrifugation, Isopycnic; Circular Dichroism; Cyclic AMP-Dependent Protein Kinases; DNA Probes; DNA-Binding Proteins; G-Box Binding Factors; Genes, Reporter; Glutamic Acid; Glycine; Hot Temperature; Leucine Zippers; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoproteins; Phosphorylation; Protein Binding; Protein Denaturation; Protein Engineering; Protein Structure, Secondary; Recombinant Proteins; Serine; Threonine; Transcription Factors; Transcriptional Activation; Transfection | 1997 |
Partial activation of muscle phosphorylase by replacement of serine 14 with acidic residues at the site of regulatory phosphorylation.
Topics: Animals; Aspartic Acid; Binding Sites; Enzyme Activation; Glutamic Acid; Kinetics; Muscles; Mutagenesis, Site-Directed; Phosphorylases; Phosphorylation; Phosphoserine; Protein Conformation; Protein Folding; Rabbits; Serine | 1997 |
Phosphorylation at conserved carboxyl-terminal hydrophobic motif regulates the catalytic and regulatory domains of protein kinase C.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Calcium; Cell Line; Conserved Sequence; DNA Primers; Enzyme Stability; Glutamic Acid; Glycerol; Kinetics; Liposomes; Models, Structural; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Polymerase Chain Reaction; Protein Conformation; Protein Kinase C; Protein Kinase C beta; Recombinant Proteins; Serine; Spodoptera; Thermodynamics; Transfection | 1997 |
Involvement of caspase-4(-like) protease in Fas-mediated apoptotic pathway.
Topics: Antibodies; Apoptosis; Arginine; Caspase 1; Cysteine Endopeptidases; Enzyme Precursors; fas Receptor; Glutamic Acid; HeLa Cells; Humans; Mutagenesis, Site-Directed; Point Mutation; Recombinant Proteins; Sequence Tagged Sites; Serine; Signal Transduction | 1997 |
Mutations in the C-terminal domain of Sonic Hedgehog cause holoprosencephaly.
Topics: Alanine; Amino Acid Sequence; Animals; Cell Line, Transformed; DNA Mutational Analysis; Exons; Female; Genes, Dominant; Glutamic Acid; Glycine; Hedgehog Proteins; Holoprosencephaly; Humans; Male; Molecular Sequence Data; Pedigree; Point Mutation; Proteins; Sequence Deletion; Sequence Homology, Amino Acid; Serine; Threonine; Trans-Activators; Valine | 1997 |
Heterozygous lipoprotein lipase deficiency: frequency in the general population, effect on plasma lipid levels, and risk of ischemic heart disease.
Topics: Adult; Aged; Aged, 80 and over; Apolipoprotein A-I; Asparagine; Cholesterol, HDL; Coronary Artery Disease; Female; Gene Frequency; Glutamic Acid; Glycine; Heterozygote; Humans; Isoleucine; Lipids; Lipoprotein Lipase; Male; Middle Aged; Phenotype; Point Mutation; Risk Factors; Serine; Triglycerides | 1997 |
Functional cleavage of the common cytokine receptor gamma chain (gammac) by calpain.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Calpain; CD4-Positive T-Lymphocytes; Cells, Cultured; DNA Primers; Glutamic Acid; Humans; Interleukin-2; Ionomycin; Lymphocyte Activation; Macromolecular Substances; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Proline; Protein Biosynthesis; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Cytokine; Recombinant Proteins; Sequence Alignment; Serine; Signal Transduction; Substrate Specificity; T-Lymphocytes; Threonine | 1997 |
O-Glycosylation of C-terminal tandem-repeated sequences regulates the secretion of rat pancreatic bile salt-dependent lipase.
Topics: Amino Acid Sequence; Animals; Brefeldin A; CHO Cells; Cricetinae; Cyclopentanes; DNA Probes; Galactose; Glutamic Acid; Glycosylation; Kinetics; Lipase; Monensin; Pancreas; Peptide Fragments; Proline; Rats; Recombinant Proteins; Serine; Sterol Esterase; Threonine; Transfection | 1997 |
Discrimination of amino acids mediating Ras binding from noninteracting residues affecting raf activation by double mutant analysis.
Topics: Amino Acid Substitution; Animals; Binding Sites; Cell Line; DNA Mutational Analysis; Glutamic Acid; Mutagenesis, Site-Directed; Protein Binding; Proto-Oncogene Proteins c-raf; Rabbits; ras Proteins; Saccharomyces cerevisiae; Serine; Transcriptional Activation | 1997 |
Intersubunit communication in hybrid hexamers of K89L/A163G/S380A and C320S mutants of glutamate dehydrogenase from Clostridium symbiosum.
Topics: Alanine; Allosteric Regulation; Clostridium; Dithionitrobenzoic Acid; Glutamate Dehydrogenase; Glutamic Acid; Lysine; NAD; Protein Conformation; Protein Denaturation; Protein Folding; Recombinant Proteins; Serine | 1997 |
A role for CKII phosphorylation of the cactus PEST domain in dorsoventral patterning of the Drosophila embryo.
Topics: Amino Acid Sequence; Animals; Binding Sites; Body Patterning; Casein Kinase II; DNA-Binding Proteins; Drosophila; Drosophila Proteins; Embryo, Nonmammalian; Glutamic Acid; Molecular Sequence Data; Mutation; Nuclear Proteins; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Signal Transduction; Transcription Factors | 1997 |
Myosin light chain-activating phosphorylation sites are required for oogenesis in Drosophila.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line, Transformed; Drosophila; Female; Gene Deletion; Glutamic Acid; Insect Proteins; Molecular Sequence Data; Myosin Light Chains; Oogenesis; Ovum; Phosphorylation; Serine; Threonine | 1997 |
Strychnine-sensitive glycine receptors inducing [3H]-acetylcholine release in rat caudatoputamen: a new site of action of ethanol?
Topics: Acetylcholine; Animals; Central Nervous System Depressants; Chloride Channels; Ethanol; Glutamic Acid; Glycine; Male; Putamen; Rats; Rats, Wistar; Receptors, Glycine; Serine | 1997 |
Production and utilization of amino acids by ovine placenta in vivo.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Biological Transport; Female; Fetus; Gestational Age; Glutamic Acid; Glutamine; Glycine; Maternal-Fetal Exchange; Oxygen Consumption; Placenta; Pregnancy; Regional Blood Flow; Serine; Sheep; Uterus | 1998 |
Neurotransmitters in cerebrospinal fluid reflect pathological activity.
Topics: Adult; Aged; Asparagine; Aspartic Acid; Blood-Brain Barrier; Central Nervous System Diseases; Female; Glutamic Acid; Glutamine; Glycine; Humans; L-Lactate Dehydrogenase; Male; Middle Aged; Neurotransmitter Agents; Serine; Taurine | 1997 |
Functional characterization of human N-methyl-D-aspartate subtype 1A/2D receptors.
Topics: Animals; Calcium; Cells, Cultured; DNA, Complementary; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Glycine; Humans; Kidney; Kynurenic Acid; Membrane Potentials; Molecular Sequence Data; N-Methylaspartate; Oocytes; Patch-Clamp Techniques; Pipecolic Acids; Piperidines; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Xenopus laevis | 1998 |
Phosphorylation of the kinase homology domain is essential for activation of the A-type natriuretic peptide receptor.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Atrial Natriuretic Factor; Binding Sites; Cell Line; Enzyme Activation; Glutamic Acid; Guanylate Cyclase; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Octoxynol; Peptide Mapping; Phosphopeptides; Phosphorylation; Receptors, Atrial Natriuretic Factor; Sequence Homology, Amino Acid; Serine; Threonine; Transfection | 1998 |
Characterization of D10S and K71E mutants of human cytosolic hsp70.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aspartic Acid; Clathrin; Cytochrome c Group; Cytosol; Glutamic Acid; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Lysine; Mutagenesis, Insertional; Nucleotides; Peptides; Recombinant Proteins; Serine | 1998 |
Involvement of glutamic acid 278 in the redox reaction of the cytochrome c oxidase from Paracoccus denitrificans investigated by FTIR spectroscopy.
Topics: Asparagine; Aspartic Acid; Deuterium Oxide; Electron Transport Complex IV; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Oxidation-Reduction; Paracoccus denitrificans; Serine; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared | 1998 |
Identification of functional domains of the human glutamate transporters EAAT1 and EAAT2.
Topics: Amino Acid Sequence; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 2; Gene Expression; Glutamates; Glutamic Acid; Humans; Kainic Acid; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Receptors, Neurotransmitter; Recombinant Fusion Proteins; Recombinant Proteins; Sequence Alignment; Serine; Xenopus laevis | 1998 |
Sulphur-containing amino acids are agonists for group 1 metabotropic receptors expressed in clonal RGT cell lines.
Topics: Amino Acids, Sulfur; Animals; Cell Line; Cricetinae; Cysteic Acid; Cysteine; Glutamic Acid; Homocysteine; Humans; Mesocricetus; Neurotransmitter Agents; Phosphatidylinositols; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Serine | 1998 |
Acetyl phosphate and the phosphorylation of OmpR are involved in the regulation of the cell division rate in Escherichia coli.
Topics: Acetates; Aspartic Acid; Bacterial Proteins; Carbon; Cell Division; Culture Media; Escherichia coli; Flagella; Glutamic Acid; Models, Biological; Mutation; Organophosphates; Phosphate Acetyltransferase; Phosphorylation; Serine; Signal Transduction; Threonine; Trans-Activators | 1998 |
Expression and initial characterization of a soluble glycine binding domain of the N-methyl-D-aspartate receptor NR1 subunit.
Topics: Animals; Baculoviridae; Binding Sites; Binding, Competitive; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Indoles; Kynurenic Acid; Protein Binding; Protein Conformation; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Serine; Spodoptera | 1998 |
Evidence for functional native NMDA receptors activated by glycine or D-serine alone in the absence of glutamatergic coagonist.
Topics: Animals; Cerebral Cortex; Cholecystokinin; Dose-Response Relationship, Drug; Drug Synergism; Glutamic Acid; Glycine; Male; N-Methylaspartate; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Somatostatin; Stereoisomerism; Synaptosomes | 1998 |
Two substrate interaction sites in lignin peroxidase revealed by site-directed mutagenesis.
Topics: Basidiomycota; Enzyme Stability; Glutamic Acid; Glycine; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Oxidation-Reduction; Peroxidases; Phenylalanine; Protein Folding; Recombinant Proteins; Serine; Spectrophotometry; Substrate Specificity; Tryptophan | 1998 |
Identification of the veratryl alcohol binding site in lignin peroxidase by site-directed mutagenesis.
Topics: Alanine; Amino Acid Substitution; Bacterial Proteins; Benzyl Alcohols; Binding Sites; Escherichia coli; Glutamic Acid; Hemeproteins; Kinetics; Mutagenesis, Site-Directed; Peroxidases; Recombinant Proteins; Serine | 1998 |
m-Calpain subunits remain associated in the presence of calcium.
Topics: Alanine; Animals; Calcium; Calpain; Caseins; Catalytic Domain; Cattle; Cysteine; Dimerization; Glutamic Acid; Kinetics; Macromolecular Substances; Mutagenesis, Site-Directed; Protein Binding; Recombinant Proteins; Serine | 1998 |
Attenuated neurotransmitter release and spreading depression-like depolarizations after focal ischemia in mutant mice with disrupted type I nitric oxide synthase gene.
Topics: Alanine; Animals; Brain; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Cortical Spreading Depression; Ethanolamines; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Laser-Doppler Flowmetry; Male; Membrane Potentials; Mice; Mice, Knockout; Microdialysis; Nerve Tissue Proteins; Neurotoxins; Neurotransmitter Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Serine; Taurine | 1998 |
Mutagenesis of a buried polar interaction in an SH3 domain: sequence conservation provides the best prediction of stability effects.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Chickens; Circular Dichroism; Conserved Sequence; Enzyme Stability; Glutamic Acid; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Salts; Serine; src Homology Domains; Thermodynamics | 1998 |
Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.
Topics: Adenine Phosphoribosyltransferase; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Enzyme Activation; Glutamic Acid; Guanine; Guanosine Monophosphate; Humans; Hypoxanthine Phosphoribosyltransferase; Isoleucine; Lysine; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Purines; Ribonucleotides; Serine; Structure-Activity Relationship; Substrate Specificity; Tritrichomonas foetus; Tyrosine; Xanthine | 1998 |
Identification of serine 356 and serine 363 as the amino acids involved in etorphine-induced down-regulation of the mu-opioid receptor.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Cell Line; Colforsin; Cyclic AMP; Diprenorphine; Down-Regulation; Etorphine; Glutamic Acid; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Receptors, Opioid, mu; Recombinant Fusion Proteins; Sequence Deletion; Serine; Transfection | 1998 |
Novel role of phosphorylation in Fe-S cluster stability revealed by phosphomimetic mutations at Ser-138 of iron regulatory protein 1.
Topics: Aconitate Hydratase; Aerobiosis; Alanine; Amino Acid Substitution; Anaerobiosis; Aspartic Acid; Binding Sites; Cytosol; Escherichia coli; Glutamic Acid; Iron Regulatory Protein 1; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Isoenzymes; Kinetics; Mutagenesis, Site-Directed; Phosphorylation; Protein Processing, Post-Translational; Recombinant Proteins; RNA-Binding Proteins; Serine | 1998 |
Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses.
Topics: Animals; Animals, Newborn; Brain Stem; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Hypoglossal Nerve; In Vitro Techniques; Motor Neurons; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Synapses | 1998 |
Effects of pH changes on systems ASC and B in rabbit ileum.
Topics: Amino Acid Transport Systems; Animals; Aspartic Acid; Biological Transport; Carrier Proteins; Chlorides; Female; Glutamic Acid; Hydrogen; Hydrogen-Ion Concentration; Ileum; Jejunum; Kinetics; Microvilli; Rabbits; Serine; Sodium | 1999 |
Two serine residues of the glutamate transporter GLT-1 are crucial for coupling the fluxes of sodium and the neurotransmitter.
Topics: Amino Acid Substitution; Amino Acid Transport System X-AG; Aspartic Acid; ATP-Binding Cassette Transporters; Binding Sites; Biological Transport; Glutamic Acid; Glycine; HeLa Cells; Humans; Kainic Acid; Kinetics; Mutagenesis, Site-Directed; Neurotransmitter Agents; Recombinant Proteins; Serine; Sodium | 1999 |
Cluster of differentiation antigen 4 (CD4) endocytosis and adaptor complex binding require activation of the CD4 endocytosis signal by serine phosphorylation.
Topics: Adaptor Protein Complex alpha Subunits; Adaptor Proteins, Vesicular Transport; Amino Acid Sequence; CD4 Antigens; Cytoplasm; Dipeptides; Down-Regulation; Endocytosis; Glutamic Acid; HeLa Cells; Humans; Membrane Proteins; Molecular Sequence Data; Peptide Fragments; Phorbol Esters; Phosphorylation; Serine; Signal Transduction; Surface Plasmon Resonance | 1999 |
Requirements of protein kinase cdelta for catalytic function. Role of glutamic acid 500 and autophosphorylation on serine 643.
Topics: Animals; Catalysis; Enzyme Stability; Glutamic Acid; Isoenzymes; Kinetics; Mutagenesis, Site-Directed; Mutation; Phosphopeptides; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Rats; Recombinant Proteins; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 1999 |
Raman markers of nonaromatic side chains in an alpha-helix assembly: Ala, Asp, Glu, Gly, Ile, Leu, Lys, Ser, and Val residues of phage fd subunits.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Deuterium; DNA, Single-Stranded; Glutamic Acid; Glycine; Inovirus; Isoleucine; Lysine; Molecular Sequence Data; Protein Structure, Secondary; Serine; Spectrum Analysis, Raman; Valine; Viral Proteins; Virus Assembly | 1999 |
Modulating electron density in the bound product, 4-hydroxybenzoyl-CoA, by mutations in 4-chlorobenzoyl-CoA dehalogenase near the 4-hydroxy group.
Topics: Acyl Coenzyme A; Alanine; Aspartic Acid; Binding Sites; Electrons; Glutamic Acid; Hydrolases; Models, Chemical; Mutagenesis, Site-Directed; Protein Binding; Pseudomonas; Serine; Spectrum Analysis, Raman | 1999 |
Dual specificity protein kinase activity of testis-specific protein kinase 1 and its regulation by autophosphorylation of serine-215 within the activation loop.
Topics: Alanine; Animals; Base Sequence; Catalytic Domain; COS Cells; DNA Primers; Enzyme Activation; Glutamic Acid; HeLa Cells; Humans; Mutagenesis, Site-Directed; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Serine; Substrate Specificity | 1999 |
Structural and spectral response of green fluorescent protein variants to changes in pH.
Topics: Amino Acid Substitution; Animals; Crystallography, X-Ray; Glutamic Acid; Green Fluorescent Proteins; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Luminescent Proteins; Mutagenesis, Site-Directed; Pigments, Biological; Protons; Scyphozoa; Serine; Spectrometry, Fluorescence; Structure-Activity Relationship; Threonine | 1999 |
Evaluation of the roles of the conserved residues of aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Amino Acid Sequence; Arginine; Binding Sites; Conserved Sequence; Glutamic Acid; Humans; Kinetics; Mutagenesis; NAD; Recombinant Fusion Proteins; Serine; Threonine | 1999 |
A constitutively "phosphorylated" guanylyl cyclase-linked atrial natriuretic peptide receptor mutant is resistant to desensitization.
Topics: Adenine; Amino Acid Sequence; Amino Acid Substitution; Atrial Natriuretic Factor; Enzyme Inhibitors; Glutamic Acid; Guanylate Cyclase; Humans; Microcystins; Molecular Sequence Data; Mutation; Peptides, Cyclic; Phosphorylation; Receptors, Atrial Natriuretic Factor; Recombinant Proteins; Serine; Threonine | 1999 |
Role of the ATP-binding domain of the human papillomavirus type 11 E1 helicase in E2-dependent binding to the origin.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Animals; Binding Sites; Cattle; DNA Helicases; DNA Replication; DNA-Binding Proteins; Glutamic Acid; Glutamine; Humans; Lysine; Magnesium; Papillomaviridae; Proline; Replication Origin; Saccharomyces cerevisiae; Serine; Temperature; Viral Proteins; Virus Replication | 1999 |
Optimal replication activity of vesicular stomatitis virus RNA polymerase requires phosphorylation of a residue(s) at carboxy-terminal domain II of its accessory subunit, phosphoprotein P.
Topics: Amino Acid Substitution; Animals; Binding Sites; Cell Line; Cricetinae; DNA-Directed RNA Polymerases; Glutamic Acid; Mutagenesis; Phosphates; Phosphoproteins; Phosphorylation; Serine; Transcription, Genetic; Vesicular stomatitis Indiana virus; Viral Structural Proteins; Virus Replication | 1999 |
Phosphorylation and/or presence of serine 37 in the movement protein of tomato mosaic tobamovirus is essential for intracellular localization and stability in vivo.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Binding Sites; Fluorescence; Glutamic Acid; Green Fluorescent Proteins; Intracellular Fluid; Luminescent Proteins; Molecular Sequence Data; Mutagenesis; Nicotiana; Phosphoamino Acids; Phosphorylation; Plant Viral Movement Proteins; Plants, Toxic; Protoplasts; Recombinant Fusion Proteins; Serine; Solanum lycopersicum; Threonine; Tobamovirus; Viral Proteins | 1999 |
The SNF1 kinase complex from Saccharomyces cerevisiae phosphorylates the transcriptional repressor protein Mig1p in vitro at four sites within or near regulatory domain 1.
Topics: Aspartic Acid; DNA-Binding Proteins; Enzyme Repression; Gene Expression Regulation, Fungal; Glucose; Glutamic Acid; Glutathione Transferase; Kluyveromyces; Mutagenesis, Site-Directed; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity | 1999 |
The crystal structure of a penicilloyl-serine transferase of intermediate penicillin sensitivity. The DD-transpeptidase of streptomyces K15.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Carrier Proteins; Catalytic Domain; Computer Graphics; Crystallization; Crystallography, X-Ray; Glutamic Acid; Hexosyltransferases; Models, Molecular; Molecular Sequence Data; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Penicillins; Peptidyl Transferases; Protein Structure, Secondary; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Streptomyces | 1999 |
Modulation by L- and D-isoforms of amino acids of the L-glutamate response of N-methyl-D-aspartate receptors.
Topics: Alanine; Amino Acids; Animals; Computer Simulation; Female; Glutamic Acid; Ligands; Membrane Potentials; Oocytes; Protein Isoforms; Receptors, N-Methyl-D-Aspartate; Serine; Software; Stereoisomerism; Xenopus laevis | 1999 |
Mutations of human topoisomerase II alpha affecting multidrug resistance and sensitivity.
Topics: Adenosine Triphosphate; Antigens, Neoplasm; Antineoplastic Agents; Arginine; Catalysis; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Activation; Glutamic Acid; Glutamine; Glycine; Humans; Isoenzymes; Mutagenesis, Site-Directed; Proline; Serine; Teniposide; Tumor Cells, Cultured | 1999 |
Mapping the role of active site residues for transducing an ATP-induced conformational change in the bovine 70-kDa heat shock cognate protein.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Aspartic Acid; Binding Sites; Cattle; Crystallography, X-Ray; Glutamic Acid; HSP70 Heat-Shock Proteins; Kinetics; Peptide Fragments; Peptide Mapping; Point Mutation; Protein Conformation; Recombinant Proteins; Scattering, Radiation; Serine; Solutions; Spectrometry, Fluorescence; X-Rays | 1999 |
Structure of an insulin dimer in an orthorhombic crystal: the structure analysis of a human insulin mutant (B9 Ser-->Glu).
Topics: Amino Acid Substitution; Animals; Crystallization; Crystallography, X-Ray; Dimerization; Glutamic Acid; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Insulin; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Serine; Swine | 1999 |
Relationship between the conserved alpha subunit arginine 107 and effects of phosphate on the activity and stability of Vibrio harveyi luciferase.
Topics: Alanine; Amino Acid Sequence; Arginine; Conserved Sequence; Glutamic Acid; Kinetics; Luciferases; Macromolecular Substances; Mutagenesis, Site-Directed; Phosphates; Recombinant Proteins; Serine; Vibrio | 1999 |
Peroxynitrite anion stimulates arginine release from cultured rat astrocytes.
Topics: Animals; Animals, Newborn; Arginine; Astrocytes; Cells, Cultured; Citrulline; Glutamic Acid; Hydrogen Peroxide; Kinetics; Lysine; Nitrates; Nitric Oxide Donors; Oxidants; Rats; Rats, Wistar; Serine | 1999 |
Localization of L-glutamate and glutamate-like receptors at the squid giant synapse.
Topics: Alanine; Animals; Antibody Specificity; Aspartic Acid; Blotting, Western; Chromatography, High Pressure Liquid; Decapodiformes; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Glutamic Acid; Glycine; Receptors, Glutamate; Serine; Synapses; Taurine | 1999 |
Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases.
Topics: Acetophenones; Alanine; Amino Acids; Animals; Arachidonic Acids; Aspartic Acid; Brain Edema; Cerebral Cortex; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dimethyl Sulfoxide; Enzyme Inhibitors; Estrenes; Ethanolamines; Fatty Acids, Unsaturated; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hypotonic Solutions; Male; Osmotic Pressure; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Protein Kinase C; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Serine; Solvents; Taurine; Water-Electrolyte Balance | 1999 |
Identification and characterization of the phosphorylation sites of the guanylyl cyclase-linked natriuretic peptide receptors A and B.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Cell Line; Glutamic Acid; Guanylate Cyclase; Humans; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphoproteins; Phosphorylation; Receptors, Atrial Natriuretic Factor; Recombinant Proteins; Serine; Threonine | 1999 |
A conserved serine-rich stretch in the glutamate transporter family forms a substrate-sensitive reentrant loop.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Transport System X-AG; ATP-Binding Cassette Transporters; Conserved Sequence; Cysteine; Ethylmaleimide; Glutamic Acid; Molecular Sequence Data; Serine | 1999 |
Key brain receptor gets an unusual regulator.
Topics: Animals; Astrocytes; Brain; Cloning, Molecular; Glutamic Acid; Neurons; Racemases and Epimerases; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism; Synapses | 1999 |
Hyperglycemia enhances extracellular glutamate accumulation in rats subjected to forebrain ischemia.
Topics: Alanine; Animals; Brain Ischemia; Glutamic Acid; Glutamine; Glycine; Hyperglycemia; Male; Prosencephalon; Rats; Rats, Wistar; Serine; Taurine | 2000 |
The utilization of alanine, glutamic acid, and serine as amino acid substrates for glycine N-acyltransferase.
Topics: Acyltransferases; Alanine; Animals; Cattle; Glutamic Acid; Glycine; Humans; Kinetics; Serine | 2000 |
Synthesis and conformational studies of poly(L-lysine) based branched polypeptides with Ser and Glu/Leu in the side chains.
Topics: Animals; Circular Dichroism; Glutamic Acid; Leucine; Mice; Oligopeptides; Polylysine; Protein Conformation; Protein Structure, Secondary; Serine; Solutions; Spleen | 2000 |
Effects of glyphosate and dalapon on total free amino acid profiles of Pseudosuccinea columella snails.
Topics: Alanine; Amino Acids; Animals; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Glyphosate; Herbicides; Propionates; Serine; Snails; Threonine | 2000 |
Presence of 2-furoylmethyl derivatives in hydrolysates of processed tomato products.
Topics: Alanine; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Freeze Drying; Furans; gamma-Aminobutyric Acid; Glutamic Acid; Hydrolysis; Lysine; Maillard Reaction; Serine; Solanum lycopersicum; Threonine | 2000 |
Glutamic acid mutagenesis of retinoblastoma protein phosphorylation sites has diverse effects on function.
Topics: Bone Neoplasms; Cell Cycle; Cell Line; Cyclin-Dependent Kinases; Genes, Retinoblastoma; Glutamic Acid; Humans; Kidney; Mutagenesis, Site-Directed; Osteosarcoma; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Retinoblastoma Protein; Serine; Structure-Activity Relationship; Threonine; Transfection; Tumor Cells, Cultured | 2000 |
An engineered blockage within the ammonia tunnel of carbamoyl phosphate synthetase prevents the use of glutamine as a substrate but not ammonia.
Topics: Alanine; Ammonia; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carbamyl Phosphate; Escherichia coli; Glutamic Acid; Glutamine; Glycine; Kinetics; Lysine; Methionine; Mutagenesis, Site-Directed; Phenylalanine; Serine; Substrate Specificity; Time Factors | 2000 |
Calf intestinal mucin: isolation, partial characterization, and measurement in ileal digesta with an enzyme-linked immunosorbent assay.
Topics: Abomasum; Animals; Antibody Specificity; Aspartic Acid; Carbohydrates; Cattle; Centrifugation, Density Gradient; Cesium; Chlorides; Diet; Digestion; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Ileum; Immune Sera; Intestines; Milk; Mucins; Serine; Threonine | 2000 |
A phosphorylation site regulates sorting of the vesicular acetylcholine transporter to dense core vesicles.
Topics: Amino Acid Substitution; Animals; Carrier Proteins; Cell Fractionation; Cell Membrane; Centrifugation, Density Gradient; Cloning, Molecular; COS Cells; Cytoplasmic Granules; Glutamic Acid; Leucine; Membrane Glycoproteins; Membrane Transport Proteins; Mutagenesis, Site-Directed; Neuropeptides; PC12 Cells; Phosphorylation; Point Mutation; Protein Kinase C; Rats; Recombinant Proteins; Serine; Serotonin; Synaptic Vesicles; Vesicular Acetylcholine Transport Proteins; Vesicular Biogenic Amine Transport Proteins; Vesicular Transport Proteins | 2000 |
Ser787 in the proline-rich region of human MAP4 is a critical phosphorylation site that reduces its activity to promote tubulin polymerization.
Topics: Amino Acid Sequence; Animals; Binding Sites; Glutamic Acid; Humans; Microtubule-Associated Proteins; Microtubules; Molecular Sequence Data; Mutagenesis; Phosphorylation; Polymers; Proline; Serine; Swine; Tubulin | 2000 |
Deterministic features of side-chain main-chain hydrogen bonds in globular protein structures.
Topics: Amino Acids; Asparagine; Aspartic Acid; Crystallization; Glutamic Acid; Glutamine; Histidine; Hydrogen Bonding; Protein Conformation; Protein Structure, Secondary; Proteins; Serine; Threonine | 2000 |
Regulation of tyrosine hydroxylase activity and phosphorylation at Ser(19) and Ser(40) via activation of glutamate NMDA receptors in rat striatum.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antibody Specificity; Catalytic Domain; Caudate Nucleus; Colforsin; Dihydroxyphenylalanine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Okadaic Acid; Oxidopamine; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Sympatholytics; Tyrosine 3-Monooxygenase | 2000 |
The role of Na,K-ATPase alpha subunit serine 775 and glutamate 779 in determining the extracellular K+ and membrane potential-dependent properties of the Na,K-pump.
Topics: Glutamic Acid; HeLa Cells; Humans; Membrane Potentials; Point Mutation; Potassium; Serine; Sodium-Potassium-Exchanging ATPase | 2000 |
cAMP-dependent protein kinase inhibits mGluR2 coupling to G-proteins by direct receptor phosphorylation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Amino Acid Sequence; Animals; Anticonvulsants; CHO Cells; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclopropanes; Dentate Gyrus; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoquinolines; Molecular Sequence Data; Mutagenesis; Neurons; Perforant Pathway; Phosphorylation; Protein Binding; Rats; Receptors, Metabotropic Glutamate; Serine; Sulfonamides; Transfection | 2000 |
Activation of protein kinase C stimulates the dephosphorylation of natriuretic peptide receptor-B at a single serine residue: a possible mechanism of heterologous desensitization.
Topics: Alanine; Binding Sites; Blotting, Western; Cell Line; Cell Membrane; Cyclic GMP; Detergents; Enzyme Activation; Glutamic Acid; Guanylate Cyclase; Humans; Ligands; Mutagenesis, Site-Directed; Peptide Mapping; Peptides; Phosphorylation; Plasmids; Protein Binding; Protein Kinase C; Receptors, Atrial Natriuretic Factor; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Lactate prevents the alterations in tissue amino acids, decline in ATP, and cell damage due to aglycemia in retina.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Aspartic Acid; Chickens; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; In Vitro Techniques; L-Lactate Dehydrogenase; Lactates; Retina; Serine | 2000 |
In vitro selection of fluoroquinolone-resistant Neisseria gonorrhoeae harboring alterations in DNA gyrase and topoisomerase IV.
Topics: Anti-Infective Agents; Aspartic Acid; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Genes, Bacterial; Glutamic Acid; Humans; Microbial Sensitivity Tests; Mutation; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Selection, Genetic; Serine | 2000 |
The role of Glu74 and Tyr82 in the reaction catalyzed by sheep liver cytosolic serine hydroxymethyltransferase.
Topics: Alanine; Amino Acid Substitution; Animals; Apoenzymes; Binding Sites; Calorimetry, Differential Scanning; Catalysis; Cytosol; Formaldehyde; Glutamic Acid; Glycine Hydroxymethyltransferase; Humans; Kinetics; Liver; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Rabbits; Recombinant Fusion Proteins; Serine; Sheep; Structure-Activity Relationship; Tetrahydrofolates; Tyrosine | 2000 |
Functional significance of N- and C-terminus of the amino acid transporters EAAC1 and ASCT1: characterization of chimeric transporters.
Topics: Amino Acid Sequence; Amino Acid Transport System X-AG; Amino Acid Transport Systems; Amino Acids; Animals; Base Sequence; Biological Transport, Active; Carrier Proteins; DNA Primers; Excitatory Amino Acid Transporter 3; Female; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; In Vitro Techniques; Mice; Molecular Sequence Data; Oocytes; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Symporters; Xenopus laevis | 2000 |
Methylarcula marina gen. nov., sp. nov. and Methylarcula terricola sp. nov.: novel aerobic, moderately halophilic, facultatively methylotrophic bacteria from coastal saline environments.
Topics: Alphaproteobacteria; Amino Acids, Diamino; Bacterial Typing Techniques; Base Composition; Base Sequence; Culture Media; DNA, Bacterial; DNA, Ribosomal; Genes, rRNA; Glutamic Acid; Microscopy, Electron; Molecular Sequence Data; Nucleic Acid Hybridization; Phenotype; Phylogeny; RNA, Ribosomal, 16S; Seawater; Sequence Analysis, DNA; Serine; Sodium Chloride | 2000 |
Structural and functional implications of tau hyperphosphorylation: information from phosphorylation-mimicking mutated tau proteins.
Topics: Actin Cytoskeleton; Adult; Amino Acid Sequence; Amino Acid Substitution; Glutamic Acid; Humans; Microtubules; Molecular Mimicry; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoprotein Phosphatases; Phosphorylation; Polymerase Chain Reaction; Protein Conformation; Protein Phosphatase 2; Serine; Structure-Activity Relationship; tau Proteins; Threonine | 2000 |
The conserved cysteine 7.38 residue is differentially accessible in the binding-site crevices of the mu, delta, and kappa opioid receptors.
Topics: Amino Acid Sequence; Animals; Benzomorphans; Binding Sites; Cell Line; Conserved Sequence; Cysteine; Diprenorphine; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Glutamic Acid; Humans; Indicators and Reagents; Mesylates; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Narcotic Antagonists; Protein Structure, Secondary; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serine; Time Factors; Tritium | 2000 |
Redesigning the substrate specificity of an enzyme: isocitrate dehydrogenase.
Topics: 3-Isopropylmalate Dehydrogenase; Alcohol Oxidoreductases; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Enzyme Activation; Escherichia coli; Glutamic Acid; Helix-Loop-Helix Motifs; Isocitrate Dehydrogenase; Isocitrates; Malates; Molecular Sequence Data; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Protein Engineering; Protein Structure, Secondary; Recombinant Fusion Proteins; Serine; Substrate Specificity; Thermus thermophilus; Thiobacillus; Valine | 2000 |
Calpain mutants with increased Ca2+ sensitivity and implications for the role of the C(2)-like domain.
Topics: Animals; Calcium; Calpain; Crystallography, X-Ray; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Point Mutation; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Salts; Serine | 2001 |
The structure of aspartyl dipeptidase reveals a unique fold with a Ser-His-Glu catalytic triad.
Topics: Catalytic Domain; Crystallography, X-Ray; Dipeptidases; Glutamic Acid; Histidine; Models, Molecular; Protein Structure, Secondary; Salmonella typhimurium; Serine | 2000 |
N-Terminal domain of annexin 2 regulates Ca(2+)-dependent membrane aggregation by the core domain: a site directed mutagenesis study.
Topics: Allosteric Regulation; Amino Acid Sequence; Annexin A2; Chromaffin Granules; Cloning, Molecular; Glutamic Acid; Humans; Liposomes; Membranes; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Recombinant Proteins; Saccharomyces cerevisiae; Serine | 2000 |
Effects of N-methyl-D-aspartate, kainate or veratridine on extracellular concentrations of free D-serine and L-glutamate in rat striatum: an in vivo microdialysis study.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Kainic Acid; Male; Microdialysis; N-Methylaspartate; Perfusion; Rats; Rats, Wistar; Serine; Time Factors; Veratridine | 2000 |
DNA polymerase beta: contributions of template-positioning and dNTP triphosphate-binding residues to catalysis and fidelity.
Topics: Animals; Arginine; Asparagine; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Deoxyribonucleotides; DNA Polymerase beta; DNA-Binding Proteins; Glutamic Acid; Kinetics; Lysine; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Rats; Recombinant Proteins; Serine; Structure-Activity Relationship; Templates, Genetic | 2000 |
The destabilization of human GCAP1 by a proline to leucine mutation might cause cone-rod dystrophy.
Topics: Amino Acid Sequence; Animals; Calcium; Calcium-Binding Proteins; Cell Line; Circular Dichroism; Cloning, Molecular; Cyclic GMP; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Escherichia coli; Family Health; Glutamic Acid; Guanylate Cyclase-Activating Proteins; Hot Temperature; Humans; Leucine; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Myristic Acids; Phenotype; Proline; Retinitis Pigmentosa; Sequence Homology, Amino Acid; Serine; Temperature | 2001 |
Identification of residues in the carboxy-terminal domain of Clostridium perfringens alpha-toxin (phospholipase C) which are required for its biological activities.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Toxins; Calcium-Binding Proteins; Clostridium perfringens; DNA, Bacterial; Egg Yolk; Glutamic Acid; Glycine; Hemolysis; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Phospholipids; Phosphorylcholine; Protein Conformation; Serine; Substrate Specificity; Type C Phospholipases | 2000 |
Extracellular amino acid levels measured with intracerebral microdialysis in the model of posttraumatic epilepsy induced by intracortical iron injection.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Cerebral Cortex; Craniocerebral Trauma; Electroencephalography; Epilepsy; Extracellular Space; Ferrous Compounds; Glutamic Acid; Injections; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Serine | 2001 |
Regulation of phosphotransferase activity of hexokinase 2 from Saccharomyces cerevisiae by modification at serine-14.
Topics: Amino Acid Substitution; Dimerization; Enzyme Activation; Enzyme Stability; Glutamic Acid; Hexokinase; Isoenzymes; Mutagenesis, Site-Directed; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Saccharomyces cerevisiae; Serine; Substrate Specificity | 2001 |
Kinetic characterization of the double mutant R148A/E182S of glycogen phosphorylase kinase catalytic subunit: the role of the activation loop.
Topics: Alanine; Animals; Arginine; Catalysis; Enzyme Activation; Glutamic Acid; Kinetics; Models, Molecular; Mutation; Phosphorylase Kinase; Phosphorylation; Protein Conformation; Rabbits; Serine; Substrate Specificity | 2000 |
Phosphorylation of protein phosphatase inhibitor-1 by Cdk5.
Topics: Animals; Binding Sites; Brain; Calcineurin; Carrier Proteins; CDC2 Protein Kinase; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Kinetics; Mice; Mice, Inbred C57BL; Mutagenesis, Site-Directed; N-Methylaspartate; Phosphoprotein Phosphatases; Phosphorylation; Proline; Protein Phosphatase 1; Rabbits; Rats; Recombinant Proteins; RNA-Binding Proteins; Serine; Time Factors | 2001 |
Structural basis for a change in substrate specificity: crystal structure of S113E isocitrate dehydrogenase in a complex with isopropylmalate, Mg2+, and NADP.
Topics: Amino Acid Substitution; Binding Sites; Catalysis; Crystallography, X-Ray; Escherichia coli; Freezing; Glutamic Acid; Isocitrate Dehydrogenase; Macromolecular Substances; Magnesium; Malates; NADP; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Structure-Activity Relationship; Substrate Specificity; Tyrosine | 2001 |
Antitumor action of seminal ribonuclease, its dimeric structure, and its resistance to the cytosolic ribonuclease inhibitor.
Topics: 3T3 Cells; Amino Acid Substitution; Animals; Antineoplastic Agents; Arginine; Cattle; Cytosol; Dimerization; Disulfides; Drug Resistance; Endoribonucleases; Enzyme Inhibitors; Glutamic Acid; Growth Inhibitors; Lysine; Mice; Mutagenesis, Site-Directed; Proteins; Recombinant Proteins; Semen; Serine; Tryptophan; Tumor Cells, Cultured | 2001 |
Mitochondrial phosphate transport protein. Reversions of inhibitory conservative mutations identify four helices and a nonhelix protein segment with transmembrane interactions and Asp39, Glu137, and Ser158 as nonessential for transport.
Topics: Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Biological Transport, Active; Carrier Proteins; Catalysis; Conserved Sequence; Genetic Vectors; Glutamic Acid; Liposomes; Membrane Proteins; Mitochondria; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Phosphate-Binding Proteins; Phosphates; Plasmids; Protein Conformation; Protein Structure, Secondary; Saccharomyces cerevisiae; Serine; Solubility; Transformation, Genetic | 2001 |
Derivatization and fluorescence detection of amino acids and peptides with 9-fluorenylmethyl chloroformate on the surface of a solid adsorbent.
Topics: Amino Acids; Chromatography; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Fluorenes; gamma-Aminobutyric Acid; Glutamic Acid; Indicators and Reagents; Lysine; Peptides; Phenylalanine; Reproducibility of Results; Serine; Spectrometry, Fluorescence; Substance P; Valine | 2001 |
Electrically induced release of labelled taurine, alpha- and beta-alanine, glycine, glutamate and other amino acids from rat neocortical slices in vitro.
Topics: Alanine; Animals; Aspartic Acid; Carnosine; Electric Stimulation; Glutamic Acid; Glycine; Histidine; Neocortex; Neurons; Organ Culture Techniques; Rats; Serine; Taurine; Tritium | 1976 |
Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease.
Topics: Alanine; Binding Sites; Catalytic Domain; Conserved Sequence; Crystallization; Crystallography, X-Ray; Cytomegalovirus; Dimerization; Glutamic Acid; Glutamine; Histidine; Humans; Kinetics; Mutagenesis, Site-Directed; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Serine; Serine Endopeptidases; Solvents | 2001 |
Nongenomic antiapoptotic signal transduction by estrogen in cultured cortical neurons.
Topics: Alzheimer Disease; Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Estradiol; Estrogen Replacement Therapy; Fetus; Glutamic Acid; Menopause; Nerve Degeneration; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction; Staurosporine | 2001 |
Engineering a functional blue-wavelength-shifted rhodopsin mutant.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Cattle; COS Cells; Glutamic Acid; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Photochemistry; Retinaldehyde; Rhodopsin; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thermodynamics; Threonine; Transducin | 2001 |
Characterization of Na+-coupled glutamate/aspartate transport by a rat brain astrocyte line expressing GLAST and EAAC1.
Topics: Alanine; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Blotting, Western; Carrier Proteins; Cell Line; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 3; Ganglionic Stimulants; Genistein; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Ionophores; Kainic Acid; Protein Isoforms; Protein-Tyrosine Kinases; Quaternary Ammonium Compounds; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Sodium; Symporters; Telencephalon; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Biochemical basis of type IB (E1beta ) mutations in maple syrup urine disease. A prevalent allele in patients from the Druze kindred in Israel.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Alleles; Arginine; Blotting, Western; Cell Line; Child; Child, Preschool; Chromatography, Gel; Dimerization; Dose-Response Relationship, Drug; Escherichia coli; Family Health; Female; Glutamic Acid; Guanidine; Heterozygote; Homozygote; Humans; Israel; Ketone Oxidoreductases; Kinetics; Male; Maple Syrup Urine Disease; Models, Molecular; Multienzyme Complexes; Mutation; Plasmids; Protein Binding; Sequence Analysis, DNA; Serine; Temperature; Time Factors | 2001 |
Membrane interactions of mutated forms of the influenza fusion peptide.
Topics: Alanine; Amino Acid Sequence; Deuterium; Glutamic Acid; Glycine; Hemagglutinin Glycoproteins, Influenza Virus; Kinetics; Lipid Bilayers; Membrane Fusion; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Phosphorus Isotopes; Protein Conformation; Protein Structure, Secondary; Serine; Spectroscopy, Fourier Transform Infrared; Valine; Viral Fusion Proteins | 2001 |
Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state.
Topics: Amino Acid Sequence; Apoproteins; Bacterial Proteins; Binding Sites; Conserved Sequence; Crystallography, X-Ray; Dimerization; Glutamic Acid; Hydrogen Bonding; Ion Channel Gating; Ligands; Models, Biological; Models, Molecular; Molecular Sequence Data; Periplasm; Potassium Channels; Protein Structure, Tertiary; Receptors, AMPA; Receptors, Glutamate; Serine; Solvents; Surface Properties; Thermodynamics; Water | 2001 |
Determination of amino acids by ion-exchange chromatography on filter paper spotted blood samples stored at different temperatures and for different periods: comparison with capillary and venous blood.
Topics: Adolescent; Adult; Age Factors; Amino Acids; Blood Specimen Collection; Capillaries; Chromatography, Ion Exchange; Cold Temperature; Cystine; Glutamic Acid; Histidine; Humans; Methionine; Ornithine; Paper; Reproducibility of Results; Serine; Temperature; Veins | 2001 |
Determination of free intracellular amino acids in single mouse peritoneal macrophages after naphthalene-2,3-dicarboxaldehyde derivatization by capillary zone electrophoresis with electrochemical detection.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cell Extracts; Electrochemistry; Electrophoresis, Capillary; Glutamic Acid; Glycine; Intracellular Fluid; Macrophages, Peritoneal; Mice; Naphthalenes; Serine; Taurine | 2001 |
IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells.
Topics: Animals; Binding, Competitive; Cell Line; Cell Nucleus; Cloning, Molecular; Cytoplasm; Dimerization; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Glutamic Acid; HeLa Cells; Humans; I-kappa B Proteins; Kinetics; Mice; Microscopy, Fluorescence; Models, Biological; NF-kappa B; NF-KappaB Inhibitor alpha; Nuclear Localization Signals; Plasmids; Proline; Protein Binding; Serine; Signal Transduction; Spectrometry, Fluorescence; Threonine; Time Factors; Transfection | 2001 |
Uptake of D-serine by synaptosomal P2 fraction isolated from rat brain.
Topics: Alanine; Animals; Binding, Competitive; Brain; Carrier Proteins; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Isomerism; Male; Neurons; Neurotransmitter Agents; Pharmacokinetics; Rats; Rats, Wistar; Serine; Synaptosomes; Temperature; Tritium | 2001 |
Amino acid metabolism of bovine blastocysts derived from parthenogenetically activated or in vitro fertilized oocytes.
Topics: Alanine; Amino Acids; Animals; Asparagine; Blastocyst; Cattle; Cryopreservation; Culture Techniques; Female; Fertilization in Vitro; Glutamic Acid; Glutamine; Glycine; Oocytes; Parthenogenesis; Serine | 1998 |
Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Casein Kinase II; Cell Division; Gene Deletion; Glutamic Acid; Histone Deacetylase 1; Histone Deacetylase 2; Histone Deacetylases; Humans; Jurkat Cells; Luciferases; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Repressor Proteins; Sequence Homology, Amino Acid; Serine; Transcription, Genetic; Transfection | 2001 |
RasGAP-associated endoribonuclease G3Bp: selective RNA degradation and phosphorylation-dependent localization.
Topics: 3' Untranslated Regions; Amino Acid Substitution; Animals; Base Sequence; Binding Sites; Carrier Proteins; Cell Nucleus; Cells, Cultured; Cytoplasm; DNA Helicases; Endoribonucleases; Fibroblasts; Glutamic Acid; Isoenzymes; Mice; Mice, Knockout; Molecular Sequence Data; Mutagenesis, Site-Directed; p120 GTPase Activating Protein; Phosphorylation; Poly-ADP-Ribose Binding Proteins; Proto-Oncogene Proteins c-myc; RNA Helicases; RNA Recognition Motif Proteins; RNA, Messenger; Serine; Substrate Specificity | 2001 |
Purification of kinase activity from primate parotid glands.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Chromatography, Affinity; Enzyme Inhibitors; Enzymes, Immobilized; Glutamic Acid; Glycoproteins; Golgi Apparatus; Guanosine Triphosphate; Heparin; Histatins; Hydrogen-Ion Concentration; Macaca fascicularis; Parotid Gland; Phosphopeptides; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Salivary Proteins and Peptides; Serine; Substrate Specificity | 2001 |
Two novel prevalent polymorphisms in the hormone-sensitive lipase gene have no effect on insulin sensitivity of lipolysis and glucose disposal.
Topics: Adult; Alleles; Aspartic Acid; Blood Glucose; Exons; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Glutamic Acid; Glycerol; Humans; Insulin; Insulin Resistance; Isoleucine; Kinetics; Lipolysis; Male; Mutation; Obesity; Polymorphism, Genetic; Regulatory Sequences, Nucleic Acid; Sequence Analysis, DNA; Serine; Sterol Esterase; Triglycerides | 2001 |
Specificity of the interactions between Glu-3, Ser-24, and Gln-30 within the N-terminal segment of rat liver mitochondrial overt carnitine palmitoyltransferase (L-CPT I) in determining the malonyl-CoA sensitivity of the enzyme.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; DNA Primers; Glutamic Acid; Glutamine; Malonyl Coenzyme A; Mitochondria, Liver; Palmitoyl Coenzyme A; Peptide Fragments; Pichia; Plasmids; Point Mutation; Protein Structure, Secondary; Rats; Recombinant Proteins; Serine | 2001 |
Detection of a [3Fe-4S] cluster intermediate of cytosolic aconitase in yeast expressing iron regulatory protein 1. Insights into the mechanism of Fe-S cluster cycling.
Topics: Aconitate Hydratase; Aspartic Acid; Cell Division; Cytoplasm; Cytosol; Electron Spin Resonance Spectroscopy; Glutamic Acid; Hydrogen Peroxide; Iron; Iron Regulatory Protein 1; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Mutation; Oxygen; Phosphorylation; Reactive Oxygen Species; RNA-Binding Proteins; Saccharomyces cerevisiae; Serine; Time Factors | 2002 |
Importance of Na,K-ATPase residue alpha 1-Arg544 in the segment Arg544-Asp567 for high-affinity binding of ATP, ADP, or MgATP.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Conserved Sequence; Cysteine; Glutamic Acid; Magnesium; Mutagenesis, Site-Directed; Peptide Fragments; Phosphorylation; Saccharomyces cerevisiae; Serine; Sodium-Potassium-Exchanging ATPase; Swine; Thermodynamics | 2002 |
A vibrational spectroscopic investigation of interactions of agonists with GluR0, a prokaryotic glutamate receptor.
Topics: Bacterial Proteins; Carboxylic Acids; Cyanobacteria; Deuterium Oxide; Glutamic Acid; Glutamine; Hydrogen Bonding; Ligands; Potassium Channels; Protein Binding; Protein Structure, Secondary; Receptors, Glutamate; Serine; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Static Electricity; Vibration | 2002 |
Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits.
Topics: Animals; Calcium; Cations, Divalent; Central Nervous System; Cloning, Molecular; Electrophysiology; Glutamic Acid; Glycine; Immunohistochemistry; In Situ Hybridization; Ion Transport; Magnesium; Molecular Sequence Data; N-Methylaspartate; Neurons; Oocytes; Protein Subunits; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sequence Homology; Serine; Substrate Specificity; Xenopus laevis | 2002 |
Altered regulation of SHP-2 and PTP 1B tyrosine phosphatases in cystic kidneys from bcl-2 -/- mice.
Topics: Animals; Cell Differentiation; Cytoskeletal Proteins; Epithelial Cells; Female; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Enzymologic; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Kidney Diseases, Cystic; Leukemia, B-Cell; Lymphoma, B-Cell; Male; Mice; Mice, Mutant Strains; Paxillin; Phosphoproteins; Phosphorylation; Pregnancy; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-bcl-2; Serine; SH2 Domain-Containing Protein Tyrosine Phosphatases; src Homology Domains; Threonine | 2002 |
Molecular mechanisms of calcium and magnesium binding to parvalbumin.
Topics: Amino Acid Sequence; Animals; Binding Sites; Calcium; Computer Simulation; Esocidae; Glutamic Acid; Ions; Magnesium; Models, Molecular; Molecular Sequence Data; Mutation; Nitrogen; Parvalbumins; Protein Binding; Protein Structure, Tertiary; Serine | 2002 |
RhoA and Rho kinase-dependent phosphorylation of moesin at Thr-558 in hippocampal neuronal cells by glutamate.
Topics: Animals; Brain; cdc42 GTP-Binding Protein; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Electroshock; Glutamic Acid; Hippocampus; Immunoblotting; Intracellular Signaling Peptides and Proteins; Male; Microfilament Proteins; Neurons; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Recombinant Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Subcellular Fractions; Threonine; Time Factors; Transfection | 2002 |
Substitution of the autophosphorylation site Thr516 with a negatively charged residue confers constitutive activity to mouse 3-phosphoinositide-dependent protein kinase-1 in cells.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Binding Sites; Blotting, Western; Cell Line; CHO Cells; Cricetinae; DNA, Complementary; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Insulin; Mice; Mutagenesis, Site-Directed; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Serine; Threonine; Transfection | 2002 |
Phosphatidylinositol 3-kinase is a central mediator of NMDA receptor signalling to MAP kinase (Erk1/2), Akt/PKB and CREB in striatal neurones.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cells, Cultured; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Glutamic Acid; GTP-Binding Proteins; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neurons; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-raf; ras Proteins; Receptors, N-Methyl-D-Aspartate; Serine; Virulence Factors, Bordetella | 2002 |
Glutamic acid-65 is an essential residue for catalysis in Proteus mirabilis glutathione S-transferase B1-1.
Topics: Aspartic Acid; Catalysis; Circular Dichroism; Dinitrochlorobenzene; Glutamic Acid; Glutathione; Glutathione Transferase; Kinetics; Mutagenesis, Site-Directed; Oligonucleotides; Protein Denaturation; Protein Structure, Tertiary; Proteus mirabilis; Serine; Spectrometry, Fluorescence; Temperature; Time Factors | 2002 |
Mutations of tyrosine 537 in the human estrogen receptor-alpha selectively alter the receptor's affinity for estradiol and the kinetics of the interaction.
Topics: Animals; Cell Line; Crystallography, X-Ray; DNA, Complementary; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor alpha; Glutamic Acid; Humans; Hydrogen Bonding; Insecta; Kinetics; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Peptides; Phenylalanine; Protein Binding; Protein Conformation; Receptors, Estrogen; Serine; Time Factors; Transfection; Tyrosine | 2002 |
A comparison in normal individuals and sickle cell patients of reduced glutathione precursors and their transport between plasma and red cells.
Topics: Adult; Amino Acid Transport System ASC; Amino Acid Transport System L; Anemia, Sickle Cell; Biological Transport; Carbon Monoxide; Cysteine; Enzyme Inhibitors; Erythrocytes; Female; Glutamic Acid; Glutamine; Glutathione; Glycine; Humans; Male; Middle Aged; Oxygen; Protein Kinase Inhibitors; Protein Kinases; Serine; Staurosporine | 2000 |
Inhibition of receptor-dependent urokinase signaling by specific Ser to Glu substitutions.
Topics: Amino Acid Substitution; Animals; CD4-Positive T-Lymphocytes; Cell Movement; Cytoskeletal Proteins; Enzyme Activation; Female; Glutamic Acid; Humans; Mice; Oncogene Proteins, Viral; Paxillin; Phosphoproteins; Protein Binding; Proto-Oncogene Proteins; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Receptors, Vitronectin; Serine; Signal Transduction; src-Family Kinases; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 2002 |
Role of cyclooxygenase-2 in neuronal cell cycle activity and glutamate-mediated excitotoxicity.
Topics: Animals; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cerebral Cortex; Cyclin-Dependent Kinase Inhibitor p18; Cyclin-Dependent Kinases; Cyclooxygenase 2; Enzyme Inhibitors; Excitatory Amino Acid Agents; Female; Flavonoids; Glutamic Acid; Isoenzymes; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Phosphorylation; Piperidines; Prostaglandin-Endoperoxide Synthases; Retinoblastoma Protein; RNA, Messenger; Serine; Sulfonamides; Tumor Suppressor Proteins | 2002 |
Crystallinity and solubility characteristics of hydroxyapatite adsorbed amino acid.
Topics: Adsorption; Amino Acids; Aspartic Acid; Crystallization; Durapatite; Glutamic Acid; Glycine; Materials Testing; Microscopy, Electron, Scanning; Models, Chemical; Serine; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2002 |
Release of excitatory amino acids in the penumbra of a focal cortical necrosis.
Topics: Alanine; Animals; Aspartic Acid; Cerebral Cortex; Excitatory Amino Acids; Glutamic Acid; Glycine; Male; Microdialysis; Necrosis; Rats; Serine | 2002 |
Structure-function analysis of human triacylglycerol hydrolase by site-directed mutagenesis: identification of the catalytic triad and a glycosylation site.
Topics: Animals; Catalytic Domain; Cells, Cultured; Escherichia coli; Glutamic Acid; Glycosylation; Histidine; Humans; Insecta; Lipase; Models, Molecular; Mutagenesis, Site-Directed; Recombinant Proteins; Serine; Structure-Activity Relationship | 2002 |
Activation of the plant mitochondrial alternative oxidase: insights from site-directed mutagenesis.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Arabidopsis; Catalysis; Cysteine; Dimerization; Enzyme Activation; Escherichia coli; Glutamic Acid; Glyoxylates; Mitochondria; Mitochondrial Proteins; Mutagenesis, Site-Directed; Oxidoreductases; Oxygen; Plant Proteins; Protein Conformation; Pyruvic Acid; Sequence Analysis, DNA; Serine; Structure-Activity Relationship; Succinic Acid; Water | 2002 |
Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation.
Topics: 3T3 Cells; Alanine; Animals; Carrier Proteins; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Cyclin D1; Enzyme Inhibitors; Flavonoids; G1 Phase; Glutamic Acid; Glutamine; Glutathione Transferase; Intracellular Signaling Peptides and Proteins; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Peptide Mapping; Phosphorylation; Phosphoserine; Plasmids; Protein Structure, Tertiary; ras Proteins; Resting Phase, Cell Cycle; S Phase; Serine; Time Factors; Transfection | 2002 |
Protein folding kinetics beyond the phi value: using multiple amino acid substitutions to investigate the structure of the SH3 domain folding transition state.
Topics: Amino Acids; Aspartic Acid; Dose-Response Relationship, Drug; Glutamic Acid; Guanidine; Hydrogen Bonding; Kinetics; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Folding; Serine; src Homology Domains; Thermodynamics | 2002 |
Fibroblast growth factor 1 regulates signaling via the glycogen synthase kinase-3beta pathway. Implications for neuroprotection.
Topics: Adenoviridae; Animals; beta Catenin; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Death; Cell Line; Cell Survival; Cells, Cultured; Cytoskeletal Proteins; DNA Fragmentation; Fibroblast Growth Factor 1; Genetic Vectors; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Heparin Lyase; Humans; Immunohistochemistry; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Recombinant Proteins; Serine; Signal Transduction; Time Factors; Trans-Activators | 2002 |
Receptor methylation controls the magnitude of stimulus-response coupling in bacterial chemotaxis.
Topics: Bacterial Proteins; Cell Membrane; Chemotaxis; Dose-Response Relationship, Drug; Glutamic Acid; Kinetics; Ligands; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Methylation; Methyltransferases; Protein Binding; Salmonella typhimurium; Serine | 2002 |
In vivo and in vitro phosphorylation at Ser-493 in the glutamate (E)-segment of neurofilament-H subunit by glycogen synthase kinase 3beta.
Topics: Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Brain; Cell Line; Cloning, Molecular; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Neurofilament Proteins; Phosphorylation; Precipitin Tests; Proline; Protein Binding; Protein Structure, Tertiary; Rats; Serine; Spinal Cord; Time Factors | 2002 |
Severe impairment of NMDA receptor function in mice carrying targeted point mutations in the glycine binding site results in drug-resistant nonhabituating hyperactivity.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Binding Sites; Binding, Competitive; Biogenic Amines; Corpus Striatum; Dose-Response Relationship, Drug; Drug Resistance; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; Gene Targeting; Glutamic Acid; Glycine; Heterozygote; Hippocampus; Hyperkinesis; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Neurologic Mutants; Neurons; Patch-Clamp Techniques; Phenotype; Point Mutation; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism; Stereotyped Behavior | 2002 |
Evidence of a critical architectural function for the RAG proteins in end processing, protection, and joining in V(D)J recombination.
Topics: Alanine; Amino Acid Substitution; Animals; Cell Line; Cysteine; DNA; DNA Nucleotidyltransferases; DNA-Binding Proteins; Gene Rearrangement, B-Lymphocyte; Genes, RAG-1; Glutamic Acid; Homeodomain Proteins; Humans; Macromolecular Substances; Mice; Mutagenesis, Site-Directed; Nuclear Proteins; Nucleic Acid Conformation; Phenotype; Protein Interaction Mapping; Recombinant Fusion Proteins; Recombination, Genetic; Regulatory Sequences, Nucleic Acid; Serine; Substrate Specificity; VDJ Recombinases | 2002 |
The influence of amino acids on the biomineralization of hydroxyapatite in gelatin.
Topics: Amino Acids; Aspartic Acid; Calcium Phosphates; Durapatite; Gelatin; Gels; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Microscopy, Electron, Scanning; Serine; Thermodynamics; Tromethamine; X-Ray Diffraction | 2002 |
A unique glutamic acid-lysine (EK) domain acts as a splicing inhibitor.
Topics: Amino Acid Sequence; Arginine; Carrier Proteins; Cell Nucleus; Codon; Exons; Glutamic Acid; HeLa Cells; Humans; Lysine; Molecular Sequence Data; Nuclear Proteins; Peptides; Plasmids; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; RNA Splicing; RNA-Binding Proteins; Sequence Homology, Amino Acid; Serine; Serine-Arginine Splicing Factors; Spliceosomes; Time Factors; Transcription, Genetic; Transfection | 2002 |
The entry point of the K-proton-transfer pathway in cytochrome c oxidase.
Topics: Carbon Monoxide; Conserved Sequence; Electron Transport; Electron Transport Complex IV; Glutamic Acid; Lysine; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Photolysis; Protein Subunits; Protons; Rhodobacter sphaeroides; Serine | 2002 |
Phe(475) and Glu(446) but not Ser(445) participate in ATP-binding to the alpha-subunit of Na(+)/K(+)-ATPase.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Fluorescent Dyes; Glutamic Acid; Mice; Models, Molecular; Phenylalanine; Protein Conformation; Protein Subunits; Recombinant Fusion Proteins; Serine; Sodium-Potassium-Exchanging ATPase | 2002 |
Characterization of the Ikappa B-kinase NEMO binding domain.
Topics: Animals; Carrier Proteins; Glutamic Acid; HeLa Cells; Humans; I-kappa B Kinase; Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Serine | 2002 |
The Glu-84 of the ParC subunit plays critical roles in both topoisomerase IV-quinolone and topoisomerase IV-DNA interactions.
Topics: 4-Quinolones; Anti-Infective Agents; Calcium; Catalysis; Catalytic Domain; DNA Damage; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Enzyme Stability; Glutamic Acid; Leucine; Lysine; Macromolecular Substances; Magnesium; Mutagenesis, Site-Directed; Protein Subunits; Serine; Substrate Specificity | 2002 |
The PEST sequence does not contribute to the stability of the cystic fibrosis transmembrane conductance regulator.
Topics: Amino Acid Sequence; Amino Acids; Animals; COS Cells; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cystic Fibrosis Transmembrane Conductance Regulator; Glutamic Acid; Humans; Leupeptins; Molecular Sequence Data; Multienzyme Complexes; Mutation; Plasmids; Proline; Proteasome Endopeptidase Complex; Protein Folding; Serine; Threonine; Transfection | 2002 |
Photorespiratory NH(4)(+) production in leaves of wild-type and glutamine synthetase 2 antisense oilseed rape.
Topics: Ammonia; Antisense Elements (Genetics); Brassica napus; Carbon Dioxide; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Glycine; Immunohistochemistry; Light; Microscopy, Electron; Models, Biological; Oxygen; Oxygen Consumption; Photosynthesis; Plant Leaves; Plant Transpiration; Plants, Genetically Modified; Quaternary Ammonium Compounds; Ribulose-Bisphosphate Carboxylase; Serine; Temperature | 2002 |
Autolytic processing at Glu586-Ser587 within the cysteine-rich domain of human adamalysin 19/disintegrin-metalloproteinase 19 is necessary for its proteolytic activity.
Topics: ADAM Proteins; Animals; Base Sequence; Cell Line; Cysteine; Disintegrins; DNA Primers; Glutamic Acid; Humans; Hydrolysis; Kinetics; Membrane Proteins; Metalloendopeptidases; Metalloproteases; Muscle Proteins; Mutagenesis; Protein Processing, Post-Translational; Serine; Substrate Specificity; Tetradecanoylphorbol Acetate | 2002 |
Differential Akt phosphorylation at Ser473 and Thr308 in cultured neurons after exposure to glutamate in rats.
Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromones; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Glutamic Acid; Glycogen Synthase Kinase 3; In Vitro Techniques; Morpholines; Neurons; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Serine; Threonine; Time Factors | 2002 |
Excitatory amino acid release in the spinal cord caused by plantar incision in the rat.
Topics: Animals; Asparagine; Aspartic Acid; Dermatologic Surgical Procedures; Glutamic Acid; Glutamine; Glycine; Male; Microdialysis; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord | 2002 |
ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Blotting, Northern; Bone Marrow; Cell Nucleus; Cell Transformation, Neoplastic; Conserved Sequence; DNA-Binding Proteins; Glutamic Acid; HeLa Cells; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Humans; Immunosorbent Techniques; Leukemia, Myeloid, Acute; Mice; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Peptide Fragments; Proto-Oncogenes; Recombinant Fusion Proteins; Retroviridae; Sequence Homology; Serine; Transcription Factors; Transcriptional Elongation Factors; Transfection | 2003 |
Molecular recognition at the dimer interface of a class mu glutathione transferase: role of a hydrophobic interaction motif in dimer stability and protein function.
Topics: Amino Acid Motifs; Arginine; Chromatography, Gel; Dimerization; Enzyme Stability; Glutamic Acid; Glutathione Transferase; Hydrophobic and Hydrophilic Interactions; Mutagenesis, Site-Directed; Nanotechnology; Phenylalanine; Protein Denaturation; Protein Folding; Serine; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Urea | 2002 |
Structural and thermodynamic studies on a salt-bridge triad in the NADP-binding domain of glutamate dehydrogenase from Thermotoga maritima: cooperativity and electrostatic contribution to stability.
Topics: Alanine; Arginine; Binding Sites; Crystallography, X-Ray; Cysteine; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Guanidine; Lysine; Mutagenesis, Site-Directed; NADP; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Salts; Serine; Static Electricity; Structure-Activity Relationship; Thermodynamics; Thermotoga maritima; Urea | 2002 |
A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.
Topics: Amino Acid Sequence; Animals; Apolipoprotein A-I; Arteriosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Biological Transport; Calpain; Cell Line; Cell Membrane; Cells, Cultured; Chickens; Cholesterol; Cross-Linking Reagents; Dipeptides; DNA; Dose-Response Relationship, Drug; Endopeptidases; Glutamic Acid; Hepatocytes; Humans; Ligands; Lipid Metabolism; Macrophages; Mice; Molecular Sequence Data; Phospholipids; Plasmids; Proline; Serine; Threonine; Time Factors; Transfection; Up-Regulation | 2003 |
The unusual catalytic triad of poliovirus protease 3C.
Topics: 3C Viral Proteases; Catalysis; Catalytic Domain; Cysteine; Cysteine Endopeptidases; Deuterium; Glutamic Acid; Glutamine; Glycine; Hydrogen-Ion Concentration; Kinetics; Methionine; Models, Chemical; Mutagenesis, Site-Directed; Poliovirus; Serine; Solvents; Substrate Specificity; Temperature; Thermodynamics; Viral Proteins | 2003 |
[Simultaneous determination of 18 amino acids by reversed-phase high performance liquid chromatography with precolumn phenylisothiocyanate derivatization].
Topics: Amino Acids; Animals; Aspartic Acid; Cattle; Chromatography, High Pressure Liquid; Glutamic Acid; Isothiocyanates; Norleucine; Serine; Thiocyanates | 2002 |
The C terminus of initiation factor 4E-binding protein 1 contains multiple regulatory features that influence its function and phosphorylation.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Carrier Proteins; Cell Cycle Proteins; Cell Division; Cell Line; Cell Survival; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Genetic Vectors; Glutamic Acid; Glutamine; Humans; Immunoblotting; Insulin; Models, Genetic; Molecular Sequence Data; Mutation; Peptides; Phosphoproteins; Phosphorylation; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Time Factors; Transfection | 2003 |
Function of the loop residue Thr792 in human DNA topoisomerase II alpha.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Catalysis; Cell Division; Cysteine; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Complementary; Dose-Response Relationship, Drug; Fungal Proteins; Genetic Complementation Test; Glutamic Acid; Glycine; Humans; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Plasmids; Poly-ADP-Ribose Binding Proteins; Saccharomyces cerevisiae; Serine; Threonine; Valine | 2003 |
A model of repression: CTD analogs and PIE-1 inhibit transcriptional elongation by P-TEFb.
Topics: Alanine; Animals; Binding Sites; Binding, Competitive; Blotting, Western; Caenorhabditis elegans; Caenorhabditis elegans Proteins; COS Cells; Cyclin-Dependent Kinase 9; Cyclin-Dependent Kinases; Glutamic Acid; HeLa Cells; Histidine; Humans; Models, Genetic; Mutation; Nuclear Proteins; Peptides; Phosphorylation; Plasmids; Positive Transcriptional Elongation Factor B; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Ribonucleases; RNA Polymerase II; Serine; Transcription, Genetic; Transcriptional Activation; Transfection | 2003 |
Glutamate substitutions at a PKA consensus site are consistent with inactivation of calpain by phosphorylation.
Topics: Amino Acid Substitution; Animals; Calcium; Calpain; Consensus Sequence; Cyclic AMP-Dependent Protein Kinases; Enzyme Stability; Glutamic Acid; Mutation; Phosphorylation; Rats; Serine; Threonine | 2003 |
[Cell wall components of gramicidin S resistant Staphylococcus aureus].
Topics: Anti-Bacterial Agents; Cell Wall; Drug Resistance, Bacterial; Glutamic Acid; Glycine; Gramicidin; Peptidoglycan; Serine; Staphylococcus aureus; Teichoic Acids | 2003 |
Identification of a site in GluR1 and GluR2 that is important for modulation of deactivation and desensitization.
Topics: Amino Acid Substitution; Animals; Benzothiadiazines; Binding Sites; Dioxoles; Glutamic Acid; Kinetics; Models, Molecular; Oocytes; Piperidines; Point Mutation; Receptors, AMPA; Serine; Threonine; Transfection; Xenopus laevis | 2003 |
Glutamate-dependent glutamine, aspartate and serine release from rat cortical glial cell cultures.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anti-Inflammatory Agents; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Dexamethasone; Dicarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Glutamic Acid; Glutamine; Neuroglia; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Sprague-Dawley; Serine; Time Factors | 2003 |
Deletions of any single residues in Glu40-Ser48 loop connecting a domain and the first transmembrane helix of sarcoplasmic reticulum Ca(2+)-ATPase result in almost complete inhibition of conformational transition and hydrolysis of phosphoenzyme intermedia
Topics: Adenosine Triphosphate; Animals; Asparagine; Calcium-Transporting ATPases; COS Cells; Enzyme Activation; Gene Deletion; Glutamic Acid; Hydrogen Bonding; Hydrolysis; Lysine; Microsomes; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Conformation; Protein Structure, Tertiary; Rabbits; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine | 2003 |
Phosphorylation of the N-terminal domain regulates subcellular localization and DNA binding properties of the peptidyl-prolyl cis/trans isomerase hPar14.
Topics: Blotting, Western; Cell Cycle; Cell Nucleus; Chromatin; Dichlororibofuranosylbenzimidazole; DNA; Dose-Response Relationship, Drug; Glutamic Acid; HeLa Cells; Heparin; Humans; Kinetics; Mass Spectrometry; Microscopy, Fluorescence; Mutation; NIMA-Interacting Peptidylprolyl Isomerase; Nucleic Acid Synthesis Inhibitors; Peptidylprolyl Isomerase; Phosphorylation; Plasmids; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Serine; Sodium Chloride; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Subcellular Fractions; Time Factors; Transfection | 2003 |
Lipoprotein lipase activity and common gene variants in severely hypertriglyceridemic patients with and without diabetes.
Topics: Adult; Apolipoproteins; Asparagine; Aspartic Acid; Diabetes Complications; Diabetes Mellitus; Female; Genetic Variation; Glutamic Acid; Glycine; Humans; Hyperlipoproteinemia Type IV; Lipoprotein Lipase; Male; Middle Aged; Phenotype; Serine; Severity of Illness Index | 2003 |
Gating competence of constitutively open CLC-0 mutants revealed by the interaction with a small organic Inhibitor.
Topics: 2,4-Dichlorophenoxyacetic Acid; Alanine; Animals; Binding, Competitive; Chloride Channels; Glutamic Acid; Homeostasis; Ion Channel Gating; Kinetics; Linear Models; Models, Biological; Mutation; Oocytes; Serine; Torpedo; Xenopus | 2003 |
Phosphorylation of serine 13 is required for the proper function of the Hsp90 co-chaperone, Cdc37.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Animals; Cell Cycle Proteins; Chaperonins; Drosophila Proteins; Glutamic Acid; HSP90 Heat-Shock Proteins; Humans; K562 Cells; Molecular Chaperones; Molybdenum; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Point Mutation; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Rabbits; Recombinant Proteins; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2003 |
On the structural and functional importance of the highly conserved Glu56 of Thermus thermophilus L4 ribosomal protein.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Catalytic Domain; Glutamic Acid; Glycine; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Structure, Secondary; Ribosomal Proteins; Ribosomes; Sequence Alignment; Serine; Thermus thermophilus | 2003 |
Dominating IgE-binding epitope of Bet v 1, the major allergen of birch pollen, characterized by X-ray crystallography and site-directed mutagenesis.
Topics: Allergens; Amino Acid Sequence; Animals; Antigens, Plant; Betula; Binding Sites, Antibody; Binding, Competitive; Crystallography, X-Ray; Glutamic Acid; Immunodominant Epitopes; Immunoglobulin E; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Plant Proteins; Pollen; Serine; Surface Properties | 2003 |
Nuclear annexin II negatively regulates growth of LNCaP cells and substitution of ser 11 and 25 to glu prevents nucleo-cytoplasmic shuttling of annexin II.
Topics: Active Transport, Cell Nucleus; Amino Acid Substitution; Annexin A2; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Nucleus; Cytoplasm; Exportin 1 Protein; Glutamic Acid; Humans; Karyopherins; Male; Mutation; Phosphorylation; Prostatic Neoplasms; Protein Sorting Signals; Receptors, Cytoplasmic and Nuclear; Serine | 2003 |
Tetrahydropteroyl glutamic acid in serine synthesis and degradation.
Topics: Biochemical Phenomena; Glutamic Acid; Serine | 1954 |
METABOLIC ACTIVITY IN COXIELLA BURNETII.
Topics: Acetates; Amino Acids; Carbohydrate Metabolism; Citric Acid Cycle; Coxiella; Coxiella burnetii; Fumarates; Glutamates; Glutamic Acid; Keto Acids; Ketoglutaric Acids; Malates; NAD; Oxaloacetates; Pyruvates; Research; Serine; Succinates | 1964 |
Stimulation by surangin B of endogenous amino acid release from synaptosomes.
Topics: Alanine; Amino Acids; Animals; Brain; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carboxin; Coumarins; Fungicides, Industrial; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Insecticides; Male; Mice; Mitochondria; Multienzyme Complexes; Presynaptic Terminals; Rotenone; Serine; Synaptosomes; Taurine; Uncoupling Agents | 2003 |
Altered signaling surrounding the C-lobe of cardiac troponin C in myofilaments containing an alpha-tropomyosin mutation linked to familial hypertrophic cardiomyopathy.
Topics: Animals; Blotting, Western; Calcium; Cardiomyopathy, Hypertrophic, Familial; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Mice; Mice, Transgenic; Muscle Fibers, Skeletal; Mutation; Myocardium; Phosphorylation; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Quinolines; Serine; Signal Transduction; Thiadiazines; Time Factors; Tropomyosin; Troponin C | 2003 |
Position of Pro and Ser near Glu7.32 in the extracellular loop 3 of mammalian and nonmammalian gonadotropin-releasing hormone (GnRH) receptors is a critical determinant for differential ligand selectivity for mammalian GnRH and chicken GnRH-II.
Topics: Animals; Chickens; DNA Primers; Glutamic Acid; Gonadotropin-Releasing Hormone; Kinetics; Ligands; Mammals; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Proline; Protein Conformation; Protein Structure, Secondary; Rats; Receptors, LHRH; Serine; Species Specificity; Substrate Specificity | 2004 |
Role of His-16 in turnover of T4 pyrimidine dimer glycosylase.
Topics: Alanine; Aspartic Acid; Cell Survival; Cysteine; Dimerization; DNA; DNA Glycosylases; DNA Repair; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Lysine; Models, Biological; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Phenotype; Plasmids; Serine; Time Factors; Ultraviolet Rays | 2004 |
Enzymatic and molecular characteristics of the efficiency and specificity of exfoliative toxin cleavage of desmoglein 1.
Topics: Alanine; alpha-Macroglobulins; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Cadherins; Desmoglein 1; DNA, Complementary; Dogs; Enzyme Inhibitors; Glutamic Acid; Glycine; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Point Mutation; Polymerase Chain Reaction; Precipitin Tests; Protein Binding; Protein Sorting Signals; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Serine Proteinase Inhibitors; Staphylococcus aureus; Time Factors; Toxins, Biological | 2004 |
Bidirectional regulation of neuronal nitric-oxide synthase phosphorylation at serine 847 by the N-methyl-D-aspartate receptor.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebral Cortex; Glutamic Acid; Hippocampus; Neuronal Plasticity; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Synapses | 2004 |
The structure of a universally employed enzyme: V8 protease from Staphylococcus aureus.
Topics: Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Disulfides; Glutamic Acid; Models, Molecular; Peptides; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Serine Endopeptidases; Staphylococcus aureus; Trypsin; X-Ray Diffraction | 2004 |
Prenatal administration of morphine decreases CREBSerine-133 phosphorylation and synaptic plasticity range mediated by glutamatergic transmission in the hippocampal CA1 area of cognitive-deficient rat offspring.
Topics: Animals; Cognition Disorders; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Maze Learning; Morphine; Morphine Dependence; Neuronal Plasticity; Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission | 2003 |
Genetic screening for melanocortin-4 receptor mutations in a cohort of Italian obese patients: description and functional characterization of a novel mutation.
Topics: Adolescent; Adult; Aged; Amino Acid Sequence; Animals; Child; Chlorocebus aethiops; Cohort Studies; COS Cells; Female; Genetic Testing; Glutamic Acid; Heterozygote; Humans; Italy; Lysine; Male; Middle Aged; Mutation; Mutation, Missense; Obesity; Pedigree; Phenylalanine; Receptor, Melanocortin, Type 4; Serine | 2004 |
The composition rather than position of polar residues (QxxS) drives aspartate receptor transmembrane domain dimerization in vivo.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Chemoreceptor Cells; Dimerization; DNA-Binding Proteins; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Glutamic Acid; Glutamine; Membrane Proteins; Molecular Sequence Data; Periplasmic Binding Proteins; Protein Structure, Tertiary; Receptors, Amino Acid; Receptors, Cell Surface; Recombinant Fusion Proteins; Serine; Transcription Factors | 2004 |
The C-terminal domain is the primary determinant of histone H1 binding to chromatin in vivo.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line, Tumor; Chromatin; Gene Deletion; Glutamic Acid; Green Fluorescent Proteins; Histones; Humans; Kinetics; Luminescent Proteins; Lysine; Mice; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Point Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Spectrometry, Fluorescence; Threonine; Time Factors; Transfection | 2004 |
Horseradish peroxidase mutants that autocatalytically modify their prosthetic heme group: insights into mammalian peroxidase heme-protein covalent bonds.
Topics: Animals; Carboxylic Acids; Catalysis; Cell Line; Chromatography, High Pressure Liquid; Cloning, Molecular; DNA; Electrophoresis, Polyacrylamide Gel; Genetic Variation; Glutamic Acid; Glycine; Heme; Horseradish Peroxidase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Insecta; Kinetics; Leucine; Mass Spectrometry; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Peroxidase; Phenylalanine; Porphyrins; Protein Structure, Secondary; Serine; Spectrophotometry; Time Factors; Ultraviolet Rays | 2004 |
A single amino-acid polymorphism in pocket A of HLA-A*6602 alters the auxiliary anchors compared with HLA-A*6601 ligands.
Topics: Arginine; Aspartic Acid; Chromatography, Affinity; Glutamic Acid; HLA-A Antigens; Humans; Ligands; Peptide Fragments; Polymorphism, Genetic; Protein Binding; Recombinant Proteins; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2004 |
The importance of a critical protonation state and the fate of the catalytic steps in class A beta-lactamases and penicillin-binding proteins.
Topics: Amino Acid Motifs; Bacterial Proteins; beta-Lactamases; Binding Sites; Carrier Proteins; Catalysis; Cloning, Molecular; Cysteine; Escherichia coli; Genetic Vectors; Glutamic Acid; Hexosyltransferases; Hydrogen-Ion Concentration; Ions; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Muramoylpentapeptide Carboxypeptidase; Mutation; Penicillin-Binding Proteins; Peptidyl Transferases; Protein Binding; Protons; Serine; Thermodynamics | 2004 |
Serine hydroxymethyltransferase: role of glu75 and evidence that serine is cleaved by a retroaldol mechanism.
Topics: Aldehydes; Animals; Crystallography, X-Ray; Formyltetrahydrofolates; Glutamic Acid; Glycine; Glycine Hydroxymethyltransferase; Models, Molecular; Protein Conformation; Rabbits; Serine; Structure-Activity Relationship; Tetrahydrofolates | 2004 |
Effects of p27Kip1 on cell cycle status and viability in A549 lung adenocarcinoma cells.
Topics: Adenocarcinoma; Amino Acid Substitution; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Survival; Cyclin-Dependent Kinase Inhibitor p27; Cytoplasm; Enzyme Inhibitors; Glutamic Acid; Humans; Lung Neoplasms; Phosphorylation; Serine; Threonine; Tissue Distribution; Tumor Suppressor Proteins | 2004 |
Mutation-induced quisqualic acid and ibotenic acid affinity at the metabotropic glutamate receptor subtype 4: ligand selectivity results from a synergy of several amino acid residues.
Topics: Cell Differentiation; Cell Line; Cloning, Molecular; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Ibotenic Acid; Immunohistochemistry; Kinetics; Ligands; Lysine; Models, Chemical; Models, Genetic; Models, Molecular; Mutation; Point Mutation; Protein Binding; Protein Conformation; Quisqualic Acid; Receptors, Metabotropic Glutamate; Serine; Transfection | 2004 |
Caspase-mediated specific cleavage of human histone deacetylase 4.
Topics: Amino Acid Motifs; Animals; Apoptosis; Aspartic Acid; Binding Sites; Biological Transport; Caspase 3; Caspases; Cell Death; Cell Differentiation; Cell Line, Tumor; Cell Survival; CHO Cells; Cricetinae; Cycloheximide; Cysteine Endopeptidases; Dactinomycin; Doxycycline; Genetic Vectors; Glutamic Acid; HeLa Cells; Histone Deacetylases; Humans; Models, Biological; Multienzyme Complexes; Mutagenesis, Site-Directed; Proline; Proteasome Endopeptidase Complex; Protein Binding; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Threonine; Time Factors; Ultraviolet Rays | 2004 |
The hydrogen bonds between Arg423 and Glu472 and other key residues, Asp443, Ser477, and Pro489, are responsible for the formation and a different positioning of TNP-ATP and ATP within the nucleotide-binding site of Na(+)/K(+)-ATPase.
Topics: Adenosine; Adenosine Triphosphate; Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Binding Sites; Crystallography, X-Ray; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Genetic Vectors; Glutamic Acid; Glutathione Transferase; Hydrogen; Hydrogen Bonding; Hydrolysis; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Molecular Sequence Data; Mutation; Nucleotides; Point Mutation; Proline; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Sodium-Potassium-Exchanging ATPase; Software; Spectrophotometry; Temperature | 2004 |
Crystal structure of a high-affinity variant of rat alpha-parvalbumin.
Topics: Amino Acid Substitution; Animals; Aspartic Acid; Binding Sites; Calcium; Calcium-Binding Proteins; Cations, Divalent; Crystallization; Crystallography, X-Ray; EF Hand Motifs; Glutamic Acid; Magnesium; Parvalbumins; Potassium; Protein Binding; Protein Isoforms; Protein Structure, Secondary; Rats; Serine; Solutions | 2004 |
Mnb/Dyrk1A phosphorylation regulates the interaction of dynamin 1 with SH3 domain-containing proteins.
Topics: Adaptor Proteins, Signal Transducing; Alternative Splicing; Animals; Binding Sites, Antibody; Brain; Dynamin I; Dyrk Kinases; Endocytosis; Glutamic Acid; GRB2 Adaptor Protein; Mass Spectrometry; Mutagenesis, Site-Directed; Nerve Tissue Proteins; PC12 Cells; Peptide Fragments; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proteins; Rats; Serine; src Homology Domains; src-Family Kinases | 2004 |
The effect of sugar, amino acid, metal ion, and NaCl on model Maillard reaction under pH control.
Topics: Alanine; Amino Acids; Arabinose; Arginine; Aspartic Acid; Biochemistry; Carbohydrates; Colorimetry; Copper; Cysteine; Fructose; Glucose; Glutamic Acid; Glycine max; Hot Temperature; Hydrogen-Ion Concentration; Ions; Iron; Isoleucine; Leucine; Lysine; Maltose; Metals; Models, Chemical; Phenylalanine; Proline; Serine; Sodium Chloride; Temperature; Time Factors; Valine; Xylose | 2004 |
Analysis and prediction of leucine-rich nuclear export signals.
Topics: Active Transport, Cell Nucleus; Algorithms; Artificial Intelligence; Aspartic Acid; Computational Biology; Computing Methodologies; Consensus Sequence; Databases, Protein; Glutamic Acid; Hydrophobic and Hydrophilic Interactions; Internet; Isoelectric Point; Leucine; Markov Chains; Models, Molecular; Neural Networks, Computer; Nuclear Proteins; Protein Sorting Signals; Protein Structure, Secondary; Protein Structure, Tertiary; Reproducibility of Results; ROC Curve; Sequence Alignment; Serine; Structural Homology, Protein | 2004 |
Resonance Raman analysis of the mechanism of energy storage and chromophore distortion in the primary visual photoproduct.
Topics: Animals; Cattle; Freezing; Glutamic Acid; Light; Models, Molecular; Mutagenesis, Site-Directed; Photochemistry; Protein Conformation; Protein Structure, Secondary; Protons; Rhodopsin; Schiff Bases; Serine; Species Specificity; Spectrum Analysis, Raman; Static Electricity; Thermodynamics | 2004 |
Topology scanning and putative three-dimensional structure of the extracellular binding domains of the apical sodium-dependent bile acid transporter (SLC10A2).
Topics: Amino Acid Sequence; Binding Sites; Carbohydrate Conformation; Computer Simulation; Consensus Sequence; Extracellular Space; Glutamic Acid; Glycosylation; Humans; Ligands; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Organic Anion Transporters, Sodium-Dependent; Peptide Fragments; Polymorphism, Genetic; Proline; Protein Binding; Protein Folding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Symporters | 2004 |
Conformation analysis of glu181 and ser186 in the metarhodopsin I state.
Topics: Crystallography, X-Ray; Glutamic Acid; Hydrogen Bonding; Models, Molecular; Photochemistry; Protein Conformation; Rhodopsin; Schiff Bases; Serine | 2004 |
Stabilization of beta-hairpin peptides by salt bridges: role of preorganization in the energetic contribution of weak interactions.
Topics: Amino Acid Sequence; Glutamic Acid; Kinetics; Lysine; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Conformation; Protein Folding; Protein Structure, Secondary; Serine; Static Electricity; Thermodynamics | 2003 |
BIG2, a guanine nucleotide exchange factor for ADP-ribosylation factors: its localization to recycling endosomes and implication in the endosome integrity.
Topics: ADP-Ribosylation Factors; Cell Membrane; Endosomes; Epidermal Growth Factor; Gene Expression; Glutamic Acid; Guanine Nucleotide Exchange Factors; HeLa Cells; Humans; Mutation; Protein Binding; rab GTP-Binding Proteins; rab4 GTP-Binding Proteins; Serine; Shiga Toxin 1 | 2004 |
Inhibitor-resistant class A beta-lactamases: consequences of the Ser130-to-Gly mutation seen in Apo and tazobactam structures of the SHV-1 variant.
Topics: Alanine; Amino Acid Substitution; Apoenzymes; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Catalysis; Crystallography, X-Ray; Enzyme Inhibitors; Escherichia coli Proteins; Genetic Variation; Glutamic Acid; Glycine; Hydrolysis; Models, Molecular; Mutagenesis, Site-Directed; Penicillanic Acid; Serine; Tazobactam | 2004 |
Putative NMDA receptors in Hydra: a biochemical and functional study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Binding Sites; Cell Membrane; Concanavalin A; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Glutamic Acid; Glutathione; Glycine; Hydra; Kynurenic Acid; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Serine; Strychnine | 2004 |
Minocycline prevents glutamate-induced apoptosis of cerebellar granule neurons by differential regulation of p38 and Akt pathways.
Topics: Activating Transcription Factor 2; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Calcium; Cell Count; Cell Survival; Cells, Cultured; Cerebellum; Chromatin; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glutamic Acid; Humans; Membrane Potentials; Microscopy, Confocal; Minocycline; N-Methylaspartate; Neurons; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factors | 2004 |
Comparative study of the residues 63 and 67 on the HLA-B molecule in patients with Takayasu's Arteritis.
Topics: Alleles; Amino Acid Substitution; Female; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Glutamic Acid; HLA-B Antigens; Humans; Male; Mexico; Serine; Takayasu Arteritis | 2005 |
Mutation of regulatory serines of rat tyrosine hydroxylase to glutamate: effects on enzyme stability and activity.
Topics: Amino Acid Sequence; Animals; Cyclic AMP-Dependent Protein Kinases; Dopamine; Genetic Variation; Glutamic Acid; Kinetics; Molecular Sequence Data; Mutagenesis; Oligonucleotides; Phosphorylation; Plasmids; Protein Conformation; Protein Structure, Tertiary; Rats; Serine; Spectrophotometry; Temperature; Time Factors; Tyrosine 3-Monooxygenase | 2005 |
Serine racemase: activation by glutamate neurotransmission via glutamate receptor interacting protein and mediation of neuronal migration.
Topics: Animals; Brain; Calcium; Carrier Proteins; Cell Movement; Cells, Cultured; Enzyme Activation; Glutamic Acid; Humans; Mice; Nerve Tissue Proteins; Neuroglia; Neurons; Racemases and Epimerases; Rats; Receptors, AMPA; Serine; Synaptic Transmission; Two-Hybrid System Techniques | 2005 |
PAK1 negatively regulates the activity of the Rho exchange factor NET1.
Topics: Actins; Animals; Binding Sites; Blotting, Western; Cell Cycle; Cell Line; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation; Glutamic Acid; Glutathione Transferase; Guanine Nucleotide Exchange Factors; Humans; Immunoprecipitation; Mice; NIH 3T3 Cells; Oncogene Proteins; p21-Activated Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; rhoA GTP-Binding Protein; Serine; Signal Transduction; Stress Fibers; Time Factors; Transfection | 2005 |
Phenotype and genotype of Dent's disease in three Korean boys.
Topics: Arginine; Asian People; Child; Child, Preschool; Chloride Channels; Codon, Nonsense; Diuretics; Furosemide; Genotype; Glutamic Acid; Heart Failure; Humans; Infant; Kidney Calculi; Kidney Diseases; Kidney Tubules; Male; Phenotype; Serine; Ultrasonography | 2005 |
Ser475, Glu272, Asp276, Asp327, and Asp360 are involved in catalytic activity of human tripeptidyl-peptidase I.
Topics: Amino Acid Sequence; Aminopeptidases; Animals; Aspartic Acid; Catalysis; CHO Cells; Cricetinae; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Glutamic Acid; Humans; Kinetics; Molecular Sequence Data; Mutation; Sequence Alignment; Serine; Serine Proteases; Tripeptidyl-Peptidase 1 | 2005 |
Changes in tissue protein synthesis are involved in regulating urea synthesis in rats given proteins of different quality.
Topics: Alanine; Amino Acids; Ammonia; Animals; Caseins; Dietary Proteins; Egg Proteins; Glutamic Acid; Glutens; Homeostasis; Kinetics; Liver; Male; Protein Biosynthesis; Rats; Serine; Urea | 2004 |
Structure and function of both domains of ArnA, a dual function decarboxylase and a formyltransferase, involved in 4-amino-4-deoxy-L-arabinose biosynthesis.
Topics: Amino Acid Sequence; Amino Sugars; Antimicrobial Cationic Peptides; Binding Sites; Carboxy-Lyases; Chromatography, Gel; Crystallography, X-Ray; Escherichia coli; Glutamic Acid; Kinetics; Leucovorin; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutation; Oxygen; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Selenomethionine; Sequence Homology, Amino Acid; Serine; Uridine Diphosphate; Uridine Diphosphate Glucuronic Acid | 2005 |
Identification of amino acids required for the functional up-regulation of human dihydrofolate reductase protein in response to antifolate Treatment.
Topics: Amino Acids; Animals; Binding Sites; Blotting, Western; Catalysis; Cell Survival; CHO Cells; Cloning, Molecular; Cricetinae; Cysteine; DNA Primers; Folic Acid Antagonists; Gene Expression Regulation, Enzymologic; Glutamic Acid; Glutathione Transferase; Green Fluorescent Proteins; Humans; Inhibitory Concentration 50; Kinetics; Leucine; Methotrexate; Microscopy, Fluorescence; Models, Biological; Mutagenesis, Site-Directed; Mutation; NADP; Protein Biosynthesis; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Spectrophotometry; Tetrahydrofolate Dehydrogenase; Time Factors; Transcription, Genetic; Transfection; Up-Regulation | 2005 |
Computer simulation of explicit proton translocation in cytochrome c oxidase: the D-pathway.
Topics: Animals; Biophysics; Cattle; Computer Simulation; Crystallography, X-Ray; Electron Transport Complex IV; Glutamic Acid; Mitochondria; Models, Molecular; Models, Statistical; Mutagenesis; Protons; Serine; Static Electricity; Thermodynamics; Time Factors; Water | 2005 |
Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2.
Topics: Arginine; Bacillus; Crystallization; Crystallography, X-Ray; Glutamic Acid; Hordeum; Hydrogen Bonding; Hydrolysis; Methionine; Mutagenesis, Site-Directed; Peptides; Plant Proteins; Protein Binding; Serine; Serine Proteinase Inhibitors; Solvents; Structure-Activity Relationship; Subtilisins; Threonine | 2005 |
Point mutations at the type I Cu ligands, Cys457 and Met467, and at the putative proton donor, Asp105, in Myrothecium verrucaria bilirubin oxidase and reactions with dioxygen.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Copper; Cysteine; Dithionite; Fungal Proteins; Glutamic Acid; Glutamine; Hypocreales; Ligands; Methionine; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Point Mutation; Protons; Serine | 2005 |
Release of oxidized plastocyanin from photosystem I limits electron transfer between photosystem I and cytochrome b6f complex in vivo.
Topics: Animals; Binding Sites; Chlamydomonas; Cytochrome b6f Complex; Dose-Response Relationship, Drug; Electrons; Glutamic Acid; Glutamine; Kinetics; Mutation; NADP; Oxygen; Phenotype; Photosynthesis; Photosystem I Protein Complex; Plastocyanin; Protein Binding; Serine; Spectrophotometry; Time Factors; Tryptophan | 2005 |
Base catalysis of chromophore formation in Arg96 and Glu222 variants of green fluorescent protein.
Topics: Amino Acid Sequence; Anions; Arginine; Carbon; Catalysis; Glutamic Acid; Glycine; Green Fluorescent Proteins; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrogen; Peptides; Protein Binding; Protons; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry; Temperature; Time Factors; Trypsin; Tyrosine; Ultraviolet Rays | 2005 |
Site-directed disulfide mapping of residues contributing to the Ca2+ and K+ binding pocket of the NCKX2 Na+/Ca2+-K+ exchanger.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Calcium; Cell Line; Cell Membrane; Cross-Linking Reagents; Cysteine; Disulfides; Glutamic Acid; Humans; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Molecular Sequence Data; Mutagenesis, Insertional; Peptide Mapping; Phenanthrolines; Potassium; Protein Sorting Signals; Protein Structure, Secondary; Repetitive Sequences, Amino Acid; Serine; Sodium-Calcium Exchanger | 2005 |
Expression and characterization of the carboxyl esterase Rv3487c from Mycobacterium tuberculosis.
Topics: Amino Acid Sequence; Carboxylesterase; Catalytic Domain; Chromatography, Affinity; Cloning, Molecular; Detergents; Enteropeptidase; Enzyme Stability; Escherichia coli; Gene Expression; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; Protein Structure, Tertiary; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Serine; Temperature; Thioredoxins | 2005 |
Identification of Ser153 in ICL2 of the gonadotropin-releasing hormone (GnRH) receptor as a phosphorylation-independent site for inhibition of Gq coupling.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; COS Cells; DNA Primers; Epitopes; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gq-G11; Hydrolysis; Immunoblotting; Inositol Phosphates; Kinetics; MAP Kinase Signaling System; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Phosphorylation; Plasmids; Polymerase Chain Reaction; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rats; Receptors, LHRH; Serine; Threonine; Time Factors; Transfection | 2005 |
Neuronal transmission stimulates the phosphorylation of Kv1.4 channel at Ser229 through protein kinase A1.
Topics: Animals; Binding Sites; Brain; Calcium Signaling; Cell Line; Cells, Cultured; Conserved Sequence; Cyclic AMP-Dependent Protein Kinases; Glutamic Acid; Humans; Kv1.4 Potassium Channel; Neural Pathways; Phosphorylation; Potassium; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Sodium Channel Blockers; Synapses; Synaptic Transmission; Up-Regulation | 2005 |
Structure of the BRCT repeat domain of MDC1 and its specificity for the free COOH-terminal end of the gamma-H2AX histone tail.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Breast Neoplasms; Calorimetry; Cell Cycle Proteins; Crystallography, X-Ray; DNA Damage; DNA-Binding Proteins; Escherichia coli; Glutamic Acid; Glutamine; Glutathione Transferase; Histones; Humans; Models, Molecular; Models, Statistical; Molecular Sequence Data; Nuclear Proteins; Peptides; Phosphates; Phosphopeptides; Phosphorylation; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Trans-Activators; Tyrosine | 2005 |
Evidence that Akt mediates platelet-derived growth factor-dependent increases in activity and surface expression of the neuronal glutamate transporter, EAAC1.
Topics: Animals; Biological Transport; Biotinylation; Blotting, Western; Cell Line, Tumor; Cloning, Molecular; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Transporter 3; Gene Expression; Genetic Engineering; Glioma; Glutamic Acid; Mice; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Serine; Sodium; Transfection | 2005 |
Insights on the evolution of metabolic networks of unicellular translationally biased organisms from transcriptomic data and sequence analysis.
Topics: Ammonia; Bacteria, Aerobic; Evolution, Molecular; Ferredoxins; Genome, Bacterial; Genome, Fungal; Genomics; Glutamic Acid; Glycolysis; Metabolism; Methane; Photosynthesis; Protein Biosynthesis; Saccharomyces cerevisiae; Sequence Analysis, DNA; Serine; Species Specificity; Transcription, Genetic | 2005 |
Phosphorylation by protein kinase a inhibits nuclear import of 5-lipoxygenase.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alanine; Animals; Arachidonate 5-Lipoxygenase; Binding Sites; Biological Transport; Cell Nucleus; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Dinoprostone; Gene Expression; Glutamic Acid; Green Fluorescent Proteins; Kinetics; Mice; Mutagenesis, Site-Directed; NIH 3T3 Cells; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Recombinant Fusion Proteins; Serine; Structure-Activity Relationship; Transfection | 2005 |
Ab initio QM/MM study of class A beta-lactamase acylation: dual participation of Glu166 and Lys73 in a concerted base promotion of Ser70.
Topics: Acylation; beta-Lactamases; Glutamic Acid; Lysine; Models, Molecular; Penicillanic Acid; Serine; Thermodynamics | 2005 |
Measuring the effect of glutamate receptor agonists on extracellular D-serine concentrations in the rat striatum using online microdialysis-capillary electrophoresis.
Topics: Animals; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Electrophoresis, Capillary; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Online Systems; Rats; Rats, Sprague-Dawley; Serine; Time Factors | 2006 |
Mutations in mtDNA-encoded cytochrome c oxidase subunit genes causing isolated myopathy or severe encephalomyopathy.
Topics: Adult; DNA Mutational Analysis; Electron Transport Complex IV; Glutamic Acid; Humans; Immunohistochemistry; Male; Mitochondrial Encephalomyopathies; Muscle, Skeletal; Muscular Diseases; Mutation; Proline; Reverse Transcriptase Polymerase Chain Reaction; Rhabdomyolysis; RNA, Messenger; Serine | 2005 |
Cellular distribution of D-serine, serine racemase and D-amino acid oxidase in the rat vestibular sensory epithelia.
Topics: Animals; D-Amino-Acid Oxidase; Epithelium; Excitatory Amino Acid Transporter 1; Glutamic Acid; Immunohistochemistry; Male; Microscopy, Confocal; Neurotransmitter Agents; Organelles; Racemases and Epimerases; Rats; Rats, Wistar; Serine; Synapses; Vestibule, Labyrinth | 2006 |
Akt kinase phosphorylation of inositol 1,4,5-trisphosphate receptors.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Apoptosis; Calcium; Calcium Channels; Calcium-Transporting ATPases; Caspase 3; Caspases; Cell Line; Chlorocebus aethiops; CHO Cells; Chromones; COS Cells; Cricetinae; Detergents; DNA, Complementary; Enzyme Activation; Glutamic Acid; Humans; Immunoprecipitation; Inositol 1,4,5-Trisphosphate Receptors; Microcirculation; Molecular Sequence Data; Morpholines; Octoxynol; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Cytoplasmic and Nuclear; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine; Staurosporine; Time Factors; Transfection | 2006 |
Immunocytochemical analysis of D-serine distribution in the mammalian brain reveals novel anatomical compartmentalizations in glia and neurons.
Topics: Aging; Animals; Biomarkers; Brain; Brain Chemistry; Fixatives; Formaldehyde; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamic Acid; Glycine; Immunohistochemistry; Microscopy, Electron; Neuroglia; Neurons; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Glutamate; Serine; Synaptic Vesicles; Tissue Fixation | 2006 |
Phospholemman inhibition of the cardiac Na+/Ca2+ exchanger. Role of phosphorylation.
Topics: Adenosine Triphosphatases; Alanine; Animals; Calsequestrin; Cell Line; Cloning, Molecular; Colforsin; Cyclic AMP-Dependent Protein Kinases; Glutamic Acid; Humans; Immunoblotting; Ions; Membrane Proteins; Mice; Mice, Knockout; Muscle Cells; Muscles; Mutation; Myocardium; Phosphoproteins; Phosphorylation; Serine; Sodium; Sodium-Calcium Exchanger; Tetradecanoylphorbol Acetate; Transfection | 2006 |
Potentiation of the NMDA receptor-mediated responses through the activation of the glycine site by microglia secreting soluble factors.
Topics: Animals; Animals, Newborn; Cell Communication; Cells, Cultured; Culture Media, Conditioned; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Microglia; N-Methylaspartate; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission | 2006 |
Effects of an S84E mutation of bovine growth hormone in transgenic mice.
Topics: Acetic Acid; Animals; Blotting, Southern; Body Weight; Female; Glutamic Acid; Growth Hormone; Insulin-Like Growth Factor I; Kidney; Male; Mice; Mice, Transgenic; Mutation; Phenotype; Serine | 2006 |
Structural scaffold of 18-crown-6 tetracarboxylic Acid for optical resolution of chiral amino acid: x-ray crystal analyses of complexes of D- and L-isomers of serine and glutamic acid.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Crown Ethers; Crystallography, X-Ray; Glutamic Acid; Isomerism; Molecular Structure; Serine | 2006 |
GDNF abates serum deprivation-induced tyrosine hydroxylase Ser19 phosphorylation and activity.
Topics: Analysis of Variance; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Tumor; Cells, Cultured; Culture Media, Serum-Free; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Gene Expression Regulation, Neoplastic; Glial Cell Line-Derived Neurotrophic Factor; Glutamic Acid; Humans; Mesencephalon; N-Methylaspartate; Neuroblastoma; Neurons; Phosphorylation; Rats; Serine; Time Factors; Tyrosine 3-Monooxygenase | 2006 |
Syndapin I is the phosphorylation-regulated dynamin I partner in synaptic vesicle endocytosis.
Topics: Acyltransferases; Alanine; Animals; Animals, Newborn; Binding Sites; Calcineurin; Carrier Proteins; Cells, Cultured; Cytoskeletal Proteins; Dynamin I; Endocytosis; Glutamic Acid; Macromolecular Substances; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Peptides; Phosphorylation; Presynaptic Terminals; Protein Binding; Rats; Rats, Sprague-Dawley; Serine; Synaptic Transmission; Synaptic Vesicles; Synaptosomes | 2006 |
Correlation between plasma levels of glutamate, alanine and serine with severity of depression.
Topics: Adult; Alanine; Amino Acids; Chromatography, High Pressure Liquid; Depressive Disorder; Female; Glutamic Acid; Humans; Male; Psychiatric Status Rating Scales; Serine; Spectrometry, Fluorescence | 2006 |
Single-channel analysis of a point mutation of a conserved serine residue in the S2 ligand-binding domain of the NR2A NMDA receptor subunit.
Topics: Animals; Cells, Cultured; Female; Gene Expression Regulation; Glutamic Acid; Ion Channel Gating; Membrane Potentials; Oocytes; Patch-Clamp Techniques; Point Mutation; Protein Binding; Protein Structure, Tertiary; Receptors, N-Methyl-D-Aspartate; Serine; Xenopus laevis | 2006 |
Age-related effects of the neuromodulator D-serine on neurotransmission and synaptic potentiation in the CA1 hippocampal area of the rat.
Topics: Aging; Animals; Dose-Response Relationship, Drug; Electrophysiology; Glutamic Acid; Glycine; Hippocampus; Long-Term Potentiation; Male; Nerve Net; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Synaptic Transmission | 2006 |
Antimicrobial actions of benzimidazoles against the oral anaerobes Fusobacterium nucleatum and Prevotella intermedia.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amino Acids; Aminopeptidases; Anaerobiosis; Anti-Infective Agents; Enzyme Inhibitors; Fermentation; Fructose; Fusobacterium nucleatum; Glucose; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Lansoprazole; Lysine; Mouth; Oxygen; Prevotella intermedia; Serine | 2006 |
C-terminal amino acid residue loss for deprotonated peptide ions containing glutamic acid, aspartic acid, or serine residues at the C-terminus.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Cyclotrons; Glutamic Acid; Mass Spectrometry; Oxygen Isotopes; Peptides; Protons; Serine | 2006 |
Considerations on the lactate consumption by CHO cells in the presence of galactose.
Topics: Alanine; Animals; Asparagine; Bioreactors; Carbohydrate Metabolism; Cell Culture Techniques; Cell Survival; CHO Cells; Cricetinae; Culture Media; Galactose; Gluconeogenesis; Glucose; Glutamic Acid; Lactic Acid; Models, Biological; Serine | 2006 |
Taurine potentiates presynaptic NMDA receptors in hippocampal Schaffer collateral axons.
Topics: Animals; Axons; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Hippocampus; Kynurenic Acid; Male; N-Methylaspartate; Organ Culture Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission; Taurine | 2006 |
Catalytic role of proton transfers in the formation of a tetrahedral adduct in a serine carboxyl peptidase.
Topics: Aspartic Acid; Aspartic Acid Endopeptidases; Binding Sites; Carboxypeptidases; Catalysis; Computer Simulation; Energy Transfer; Enzyme Inhibitors; Glutamic Acid; Hydrogen-Ion Concentration; Protons; Serine; Thermodynamics | 2006 |
Prospective study of FGFR3 mutations as a prognostic factor in nonmuscle invasive urothelial bladder carcinomas.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Cysteine; Female; Glutamic Acid; Glycine; Humans; Leucine; Male; Middle Aged; Multivariate Analysis; Mutation; Phenylalanine; Polymerase Chain Reaction; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Receptor, Fibroblast Growth Factor, Type 3; Sequence Analysis, DNA; Serine; Tyrosine; Urinary Bladder Neoplasms | 2006 |
Determination of d-serine and related neuroactive amino acids in human plasma by high-performance liquid chromatography with fluorimetric detection.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Cysteine; Fluorometry; Glutamic Acid; Glutamine; Humans; Molecular Structure; o-Phthalaldehyde; Serine; Stereoisomerism | 2006 |
Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis.
Topics: ADP-ribosyl Cyclase 1; Amino Acid Substitution; Base Sequence; Binding Sites; Catalysis; Cold Temperature; Crystallography, X-Ray; Cyclic ADP-Ribose; Dimerization; Enzyme Stability; Glutamic Acid; Guanosine Diphosphate Sugars; Humans; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Kinetics; Models, Molecular; Molecular Sequence Data; NAD; NAD+ Nucleosidase; Sequence Homology, Nucleic Acid; Serine; Static Electricity; Substrate Specificity; Water | 2006 |
The uptake of amino acids by the cyanobacterium Planktothrix rubescens is stimulated by light at low irradiances.
Topics: Acetates; Alanine; Amino Acids; Carbon Isotopes; Cyanobacteria; Dose-Response Relationship, Radiation; Glutamic Acid; Glycine; Leucine; Light; Nitrogen; Serine | 2006 |
Acute flaccid paralysis as initial symptom in 4 patients with novel E1alpha mutations of the pyruvate dehydrogenase complex.
Topics: Adolescent; Arginine; Child; Child, Preschool; DNA Mutational Analysis; Family Health; Glutamic Acid; Humans; Leucine; Lysine; Magnetic Resonance Imaging; Male; Mutation; Neural Conduction; Protein Subunits; Pyruvate Dehydrogenase Complex; Quadriplegia; Serine | 2006 |
Structure/function relationships of CCR8 agonists and antagonists. Amino-terminal extension of CCL1 by a single amino acid generates a partial agonist.
Topics: Aspartic Acid; Binding Sites; Calcium; Chemokine CCL1; Chemokine CCL4; Chemokines, CC; Chemotaxis; Glutamic Acid; Ligands; Macrophage Inflammatory Proteins; Protein Binding; Protein Structure, Tertiary; Receptors, CCR8; Receptors, Chemokine; Serine; Structure-Activity Relationship; Viral Proteins | 2006 |
Glutamate reduces secretion of l-serine in astrocytes isolated from stroke-prone spontaneously hypertensive rats.
Topics: Analysis of Variance; Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; Culture Media, Conditioned; Dose-Response Relationship, Drug; Embryo, Mammalian; Gene Expression Regulation; Glutamic Acid; Heat-Shock Proteins; Hydrogen Peroxide; Interleukin-1; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Species Specificity; Time Factors | 2006 |
Modulation of the W748S mutation in DNA polymerase gamma by the E1143G polymorphismin mitochondrial disorders.
Topics: Amino Acid Sequence; Amino Acid Substitution; Catalytic Domain; DNA; DNA Polymerase gamma; DNA-Directed DNA Polymerase; Enzyme Stability; Glutamic Acid; Glycine; Humans; Mitochondrial Diseases; Models, Molecular; Molecular Sequence Data; Mutation; Nucleotides; Polymorphism, Genetic; Protein Conformation; Serine; Tryptophan | 2006 |
A CSF and postmortem brain study of D-serine metabolic parameters in schizophrenia.
Topics: Adolescent; Adult; Aged; Brain; D-Amino-Acid Oxidase; Female; Frontal Lobe; Glutamic Acid; Glutamine; Hippocampus; Humans; Male; Middle Aged; Parietal Lobe; Racemases and Epimerases; Reference Values; Schizophrenia; Serine | 2007 |
Amino acid contribution to protein solubility: Asp, Glu, and Ser contribute more favorably than the other hydrophilic amino acids in RNase Sa.
Topics: Amino Acids; Ammonium Sulfate; Aspartic Acid; Electric Conductivity; Exoribonucleases; Glutamic Acid; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Protein Structure, Tertiary; Proteins; Ribonucleases; Salts; Serine; Solubility; Structure-Activity Relationship | 2007 |
Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans.
Topics: Amino Acid Sequence; Animals; Anxiety; Behavior, Animal; Cell Movement; Cerebral Cortex; Chromosome Mapping; Dimerization; DNA Mutational Analysis; Female; Glutamic Acid; Guanosine Triphosphate; Hippocampus; Humans; Male; Memory Disorders; Mice; Mice, Mutant Strains; Molecular Sequence Data; Mutation; Neurons; Phenotype; Serine; Tubulin | 2007 |
Modeling of a human circadian mutation yields insights into clock regulation by PER2.
Topics: Amino Acid Sequence; Animals; Biological Clocks; Casein Kinase I; Cell Nucleus; Circadian Rhythm; Gene Expression Regulation; Glutamic Acid; Humans; Mice; Mice, Transgenic; Models, Biological; Molecular Sequence Data; Mutant Proteins; Mutation; Nuclear Proteins; Peptides; Period Circadian Proteins; Phenotype; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; RNA, Messenger; Serine; Transcription Factors; Transcription, Genetic | 2007 |
Frequency of the LRRK2 G2019S mutation in Italian patients affected by Parkinson's disease.
Topics: Adult; DNA Mutational Analysis; Female; Glutamic Acid; Humans; Italy; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Middle Aged; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine | 2007 |
Strengths of hydrogen bonds involving phosphorylated amino acid side chains.
Topics: Amides; Amino Acids; Aspartic Acid; Computer Simulation; Glutamic Acid; Hydrogen Bonding; Phosphorylation; Protein Processing, Post-Translational; Serine; Sodium Chloride | 2007 |
High-affinity glycine and glutamate transport in pig forebrain white and gray matter: a quantitative study.
Topics: Animals; Biological Transport; Excitatory Amino Acid Transporter 2; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Glutathione; Glycine; Glycine Hydroxymethyltransferase; Glycine Plasma Membrane Transport Proteins; Kainic Acid; Prosencephalon; Sarcosine; Serine; Swine | 2007 |
Phosphomimetic mutation of Ser-187 of SNAP-25 increases both syntaxin binding and highly Ca2+-sensitive exocytosis.
Topics: Animals; Binding Sites; Calcium; Calcium Signaling; Catecholamines; Cattle; Chromaffin Cells; Exocytosis; Glutamic Acid; Kinetics; Mutation; Patch-Clamp Techniques; Phosphorylation; Protein Kinase C; Qa-SNARE Proteins; Recombinant Proteins; Serine; Synaptosomal-Associated Protein 25; Synaptotagmin I | 2007 |
D-amino acid formation in sterilized alkali-treated olives.
Topics: Amino Acids; D-Aspartic Acid; Glutamic Acid; Hydrogen-Ion Concentration; Isomerism; Leucine; Olea; Serine; Sterilization | 2007 |
Aspartate-444 is essential for productive substrate interactions in a neuronal glutamate transporter.
Topics: Alanine; Animals; Aspartic Acid; Binding Sites; Cysteine; Dicarboxylic Acid Transporters; Excitatory Amino Acid Transporter 3; Glutamic Acid; HeLa Cells; Humans; Microinjections; Mutation; Neurons; Oocytes; Protein Conformation; Protein Structure, Tertiary; Rabbits; Serine; Succinic Acid; Transfection; Xenopus laevis | 2007 |
Increased levels of glutamate in brains from patients with mood disorders.
Topics: Adult; Aged; Amino Acids; Animals; Autopsy; Brain Chemistry; Depressive Disorder, Major; Female; Glutamic Acid; Humans; Male; Mice; Mice, Inbred ICR; Middle Aged; Mood Disorders; Serine | 2007 |
D-Serine inhibits AMPA receptor-mediated current in rat hippocampal neurons.
Topics: Action Potentials; Amino Acids; Aminobutyrates; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kainic Acid; Molecular Structure; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism; Valine | 2007 |
Identification of the cysteine residue exposed by the conformational change in pig heart succinyl-CoA:3-ketoacid coenzyme A transferase on binding coenzyme A.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Coenzyme A; Coenzyme A-Transferases; Crystallography, X-Ray; Cysteine; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Models, Chemical; Models, Molecular; Myocardium; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Swine | 2007 |
D-serine is a key determinant of glutamate toxicity in amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Enzyme Activation; Enzyme Induction; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Humans; Mice; Mice, Transgenic; Middle Aged; Motor Neurons; Mutation; N-Methylaspartate; Neuroglia; p38 Mitogen-Activated Protein Kinases; Racemases and Epimerases; Serine; Spinal Cord; Superoxide Dismutase; Up-Regulation | 2007 |
Protein kinase C regulates expression and function of inhibitory killer cell Ig-like receptors in NK cells.
Topics: Amino Acid Substitution; Casein Kinase II; Cell Line; Cell Line, Transformed; Cell Line, Tumor; Cytotoxicity, Immunologic; Down-Regulation; Glutamic Acid; Humans; Killer Cells, Natural; Phosphorylation; Protein Kinase C; Receptors, KIR; Receptors, KIR3DL1; Serine; Substrate Specificity; Threonine | 2007 |
D-serine regulates CREB phosphorylation induced by NMDA receptor activation in Müller glia from the retina.
Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Gene Expression Regulation; Glutamic Acid; Hippocampus; Neuroglia; Neurons; Phosphorylation; Proto-Oncogene Proteins c-fos; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Retina; Serine; Synaptic Transmission; Transcriptional Activation | 2007 |
Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus.
Topics: Action Potentials; Animals; Butadienes; Cells, Cultured; Citrus; Cyclic AMP-Dependent Protein Kinases; Flavones; Fruit; Glutamic Acid; Hippocampus; Isoquinolines; MAP Kinase Kinase Kinases; Mice; Neurons; Nitriles; Nootropic Agents; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Serine; Sulfonamides; Synaptic Transmission; Time Factors; Tissue Culture Techniques | 2008 |
Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif.
Topics: Amino Acid Motifs; Asparagine; Biochemistry; Carbon-Carbon Lyases; Catalytic Domain; Crystallography, X-Ray; Escherichia coli; Fusarium; Glutamic Acid; Kinetics; Magnesium; Models, Chemical; Mutagenesis, Site-Directed; Serine; Tyrosine | 2008 |
Auditory nerve is affected in one of two different point mutations of the neurofilament light gene.
Topics: Acoustic Stimulation; Adolescent; Adult; Aged; Charcot-Marie-Tooth Disease; Evoked Potentials, Auditory, Brain Stem; Family Health; Female; Functional Laterality; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Neurofilament Proteins; Point Mutation; Proline; Reaction Time; Serine; Vestibulocochlear Nerve | 2008 |
Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1.
Topics: Amino Acid Transport System X-AG; Animals; Cell Line; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamic Acid; Humans; Kainic Acid; Kinetics; Male; Neuroprotective Agents; Rats; Riluzole; Serine; Synaptosomes; Transfection | 2008 |
Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Boron; Catalytic Domain; Crystallography, X-Ray; Dimerization; Enzyme Inhibitors; Glutamic Acid; Hydrogen Bonding; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; Porphyromonas gingivalis; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Substrate Specificity; Water; X-Ray Diffraction | 2008 |
The neuralized homology repeat 1 domain of Drosophila neuralized mediates nuclear envelope association and delta-dependent inhibition of nuclear import.
Topics: Active Transport, Cell Nucleus; Amino Acid Substitution; Animals; Cells, Cultured; Drosophila; Drosophila Proteins; Exportin 1 Protein; Fluorescent Dyes; Glutamic Acid; Indoles; Intracellular Signaling Peptides and Proteins; Karyopherins; Larva; Membrane Proteins; Molecular Weight; Nuclear Envelope; Plasmids; Protein Isoforms; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; Receptors, Notch; Serine; Subcellular Fractions; Ubiquitin-Protein Ligases | 2008 |
Processing of N-terminal unnatural amino acids in recombinant human interferon-beta in Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Base Sequence; Binding Sites; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamic Acid; Glycine; Histidine; Humans; Interferon Type I; Molecular Sequence Data; Protein Engineering; Recombinant Proteins; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 2008 |
A TAT-DEF-Elk-1 peptide regulates the cytonuclear trafficking of Elk-1 and controls cytoskeleton dynamics.
Topics: Animals; Cell Differentiation; Cells, Cultured; Cocaine; Corpus Striatum; Cytoskeleton; Dopamine Uptake Inhibitors; Embryo, Mammalian; Enzyme Inhibitors; ets-Domain Protein Elk-1; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Neurons; Peptides; Phosphorylation; Protein Transport; Serine; Subcellular Fractions; Transfection | 2007 |
Amino acids of the human alpha1d-adrenergic receptor involved in antagonist binding.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amino Acid Sequence; Aspartic Acid; Binding Sites; Binding, Competitive; Cell Line; Computer Simulation; Glutamic Acid; Humans; Inositol Phosphates; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylephrine; Prazosin; Protein Structure, Tertiary; Radioligand Assay; Receptors, Adrenergic, alpha-1; Serine; Structure-Activity Relationship; Sulfonamides; Tamsulosin; Transfection; Tritium | 2008 |
D-Serine/N-methyl-D-aspartate receptor signaling decreases DNA-binding activity of the transcriptional repressor DREAM in Müller glia from the retina.
Topics: Active Transport, Cell Nucleus; Animals; Animals, Newborn; Cell Differentiation; Cells, Cultured; DNA-Binding Proteins; Down-Regulation; Glutamic Acid; Immunohistochemistry; Kv Channel-Interacting Proteins; Neuroglia; Neuronal Plasticity; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Regulatory Elements, Transcriptional; Repressor Proteins; Retina; Serine; Signal Transduction; Synaptic Transmission | 2008 |
Identification of a molecular target for glutamate regulation of astrocyte water permeability.
Topics: Animals; Animals, Newborn; Aquaporin 4; Astrocytes; Benzylamines; Calcium; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Methoxyhydroxyphenylglycol; N-Methylaspartate; Permeability; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Serine; Sulfonamides; Transfection; Water | 2008 |
The role of RIM1alpha in BDNF-enhanced glutamate release.
Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Gene Expression Regulation, Enzymologic; Glutamic Acid; GTP-Binding Proteins; Hippocampus; In Vitro Techniques; MAP Kinase Kinase Kinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Serine; Sucrose; Sweetening Agents; Synaptosomes; Time Factors; Tritium | 2008 |
Protonation and conformational dynamics of GFP mutants by two-photon excitation fluorescence correlation spectroscopy.
Topics: Computer Simulation; Glutamic Acid; Green Fluorescent Proteins; Histidine; Hydrogen-Ion Concentration; Luminescent Agents; Mutation; Photons; Protein Conformation; Protons; Serine; Spectrometry, Fluorescence; Threonine | 2008 |
Development and preclinical characterisation of 99mTc-labelled Affibody molecules with reduced renal uptake.
Topics: Animals; Cell Line, Tumor; Chelating Agents; Drug Evaluation, Preclinical; Glutamic Acid; Humans; Kidney; Mice; Organotechnetium Compounds; Peptides; Protein Stability; Recombinant Fusion Proteins; Serine; Staining and Labeling; Tissue Distribution; Transplantation, Heterologous | 2008 |
Signaling pathway of glutamate in the vestibular nuclei following acute hypotension in rats.
Topics: Animals; Arsanilic Acid; Gene Expression Regulation; Glutamic Acid; Hypotension; Male; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Time Factors; Vestibular Nuclei; Vestibule, Labyrinth | 2008 |
Role of a serine residue (S278) in the pore-facing region of the housefly L-glutamate-gated chloride channel in determining sensitivity to noncompetitive antagonists.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Chloride Channels; Dose-Response Relationship, Drug; Glutamic Acid; Hexachlorocyclohexane; Houseflies; Insecticides; Ion Channel Gating; Membrane Potentials; Molecular Structure; Picrotoxin; Pyrazoles; Serine; Sesterterpenes; Sodium Chloride | 2008 |
Development of a temperature gradient focusing method for in situ extraterrestrial biomarker analysis.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Aspartic Acid; Biomarkers; Countercurrent Distribution; Electrophoresis, Microchip; Extraterrestrial Environment; Glutamic Acid; Glycine; Life; Mars; Serine; Soil; Space Flight; Stereoisomerism; Temperature; Valine | 2008 |
Rats harboring S284L Chrna4 mutation show attenuation of synaptic and extrasynaptic GABAergic transmission and exhibit the nocturnal frontal lobe epilepsy phenotype.
Topics: Age Factors; Analysis of Variance; Animals; Behavior, Animal; Cerebral Cortex; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Frontal Lobe; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hot Temperature; In Vitro Techniques; Leucine; Microscopy, Immunoelectron; Motor Activity; Motor Skills; Mutation; Neurotransmitter Agents; Nicotine; Pain Measurement; Pentylenetetrazole; Phenotype; Rats; Rats, Transgenic; Receptors, Nicotinic; Serine; Synaptic Transmission | 2008 |
Protein kinase CK2 contributes to the organization of sodium channels in axonal membranes by regulating their interactions with ankyrin G.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Ankyrins; Axons; Casein Kinase II; Cell Membrane; Cells, Cultured; Cluster Analysis; Glutamic Acid; Hippocampus; Ion Channel Gating; Molecular Sequence Data; Phosphorylation; Point Mutation; Protein Binding; Protein Kinase Inhibitors; Ranvier's Nodes; Rats; Serine; Sodium Channels | 2008 |
Presentation of cytosolically stable peptides by HLA-B27 is not dependent on the canonic interactions of N-terminal basic residues in the A pocket.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antigen Presentation; Cell Line, Tumor; Cytosol; Gene Expression Regulation; Glutamic Acid; HLA-B Antigens; HLA-B27 Antigen; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Ligands; Peptide Fragments; Protein Binding; Serine; Signal Transduction; Thermodynamics; Threonine; Tryptophan | 2009 |
Evaluation of the number of ionogenic groups of inulinase by acid-base titration.
Topics: Asparagine; Aspergillus; Fungal Proteins; Glutamic Acid; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Lysine; Protein Denaturation; Serine; Tyrosine | 2008 |
AMPA receptors in the medial amygdala are critical for establishing a neuroendocrine memory in the female rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Sequence; Amygdala; Animals; Copulation; Estrous Cycle; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Gonadal Steroid Hormones; Male; Memory; Neurons; Neurosecretory Systems; Physical Stimulation; Pseudopregnancy; Rats; Rats, Long-Evans; Receptors, AMPA; Serine; Synaptic Transmission | 2009 |
Functional characterization and in silico docking of full and partial GluK2 kainate receptor agonists.
Topics: Aspartic Acid; Binding Sites; Cell Line; Concanavalin A; GluK2 Kainate Receptor; Glutamic Acid; Humans; Protein Conformation; Receptors, Kainic Acid; Serine; Stereoisomerism | 2009 |
Introducing chemical functionality in Fmoc-peptide gels for cell culture.
Topics: 3T3 Cells; Animals; Biocompatible Materials; Cattle; Cell Adhesion; Cell Proliferation; Cell Survival; Cells, Cultured; Chondrocytes; Cytoskeleton; Dermis; DNA; Elastic Modulus; Elasticity; Fibroblasts; Fluorenes; Gene Transfer Techniques; Glutamic Acid; Humans; Hydrogels; Hydrogen Bonding; Hydrogen-Ion Concentration; Lactate Dehydrogenases; Lysine; Mice; Nanostructures; Peptides; Plasmids; Protein Structure, Secondary; Serine; Static Electricity; Tissue Scaffolds; Viscosity | 2009 |
Gas-phase IR spectroscopy of deprotonated amino acids.
Topics: Amino Acids; Anions; Aspartic Acid; Cysteine; Gases; Glutamic Acid; Phenylalanine; Protons; Serine; Spectrophotometry; Spectrophotometry, Infrared; Tyrosine | 2009 |
Fructose and glucose mediates enterotoxin production and anaerobic metabolism of Bacillus cereus ATCC14579(T).
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Bacillus cereus; Carbohydrates; Culture Media; Enterotoxins; Fermentation; Fructose; Glucose; Glutamic Acid; Polymerase Chain Reaction; RNA, Bacterial; RNA, Ribosomal, 16S; Serine | 2009 |
Release of endogenous amino acids from the hippocampus and brain stem from developing and adult mice in ischemia.
Topics: Aging; Alanine; Animals; Aspartic Acid; Brain Ischemia; Brain Stem; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Male; Mice; Potassium; Serine; Taurine; Threonine | 2009 |
Glutamatergic transmission in hydra: NMDA/D-serine affects the electrical activity of the body and tentacles of Hydra vulgaris (Cnidaria, Hydrozoa).
Topics: Analysis of Variance; Animals; Electrophysiology; Extremities; Glutamic Acid; Hydra; Motor Activity; N-Methylaspartate; Serine; Synaptic Transmission | 2009 |
Prenatal stress alters glutamatergic system responsiveness in adult rat prefrontal cortex.
Topics: Analysis of Variance; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Female; Glutamic Acid; Hippocampus; Male; Phosphorylation; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Restraint, Physical; Serine; Sex Factors; Stress, Psychological; Swimming; Threonine | 2009 |
Simultaneous efflux of endogenous D-ser and L-glu from single acute hippocampus slices during oxygen glucose deprivation.
Topics: Acute Disease; Animals; Diffusion Chambers, Culture; Glucose; Glutamic Acid; Glutamine; Hippocampus; Hypoxia-Ischemia, Brain; Isomerism; Male; Neurons; Organ Culture Techniques; Oxygen; Perfusion; Rats; Rats, Sprague-Dawley; Serine | 2009 |
Phosphorylation status of the NR2B subunit of NMDA receptor regulates its interaction with calcium/calmodulin-dependent protein kinase II.
Topics: Amino Acid Sequence; Animals; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line; Central Nervous System; Glutamic Acid; Green Fluorescent Proteins; Humans; Insecta; Mutation; Neurons; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Binding; Protein Transport; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Serine; Synaptic Transmission | 2009 |
Non-histone nuclear factor HMGB1 is phosphorylated and secreted in colon cancers.
Topics: Adenocarcinoma; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Nucleus; Colonic Neoplasms; Cytoplasm; Disease Progression; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glutamic Acid; HMGB1 Protein; Humans; Intestinal Mucosa; Mutation; Neoplasm Invasiveness; Neoplasm Proteins; Phosphorylation; Protein Kinase C; Serine; Signal Transduction; Transfection | 2009 |
Glutamate-dependent phosphorylation of the mammalian target of rapamycin (mTOR) in Bergmann glial cells.
Topics: Animals; Cells, Cultured; Chickens; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Neuroglia; Phosphorylation; Protein Kinases; Serine; TOR Serine-Threonine Kinases | 2009 |
Roles of interaction between actuator and nucleotide binding domains of sarco(endo)plasmic reticulum Ca(2+)-ATPase as revealed by single and swap mutational analyses of serine 186 and glutamate 439.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Chlorocebus aethiops; COS Cells; DNA Mutational Analysis; Endoplasmic Reticulum; Glutamic Acid; Hydrogen Bonding; Models, Biological; Molecular Conformation; Protein Structure, Tertiary; Rabbits; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine | 2009 |
Controlling peptide folding with repulsive interactions between phosphorylated amino acids and tryptophan.
Topics: Circular Dichroism; Glutamic Acid; Hydrogen-Ion Concentration; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphorylation; Phosphoserine; Protein Folding; Protein Processing, Post-Translational; Serine; Threonine; Tryptophan; Tyrosine | 2009 |
Conformational changes specific for pseudophosphorylation at serine 262 selectively impair binding of tau to microtubules.
Topics: Alzheimer Disease; Binding Sites; Circular Dichroism; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Microtubules; Models, Molecular; Mutation; Phosphorylation; Protein Conformation; Serine; tau Proteins | 2009 |
Structural, thermodynamic, and kinetic effects of a phosphomimetic mutation in dynein light chain LC8.
Topics: Binding Sites; Crystallography, X-Ray; Dimerization; Dyneins; Glutamic Acid; Kinetics; Magnetic Resonance Spectroscopy; Molecular Mimicry; Mutation; Phosphorylation; Protein Conformation; Serine; Thermodynamics | 2009 |
Alterations in GluR2 AMPA receptor phosphorylation at serine 880 following group I metabotropic glutamate receptor stimulation in the rat dorsal striatum.
Topics: Amino Acid Sequence; Animals; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Neostriatum; Neuronal Plasticity; Neurons; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Serine; Signal Transduction; Synaptic Transmission; Up-Regulation | 2010 |
Chronic hyperammonemia induces tonic activation of NMDA receptors in cerebellum.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebellum; Cyclic GMP; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hyperammonemia; In Vitro Techniques; Male; Microdialysis; Nitrates; Nitric Oxide Synthase Type I; Nitrites; Phosphorylation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine; Statistics, Nonparametric; Subcellular Fractions; Threonine | 2010 |
Dual cross-talk between nitric oxide and D-serine in astrocytes and neurons in the brain.
Topics: Aging; Animals; Animals, Newborn; Astrocytes; Brain; Brain Neoplasms; Cells, Cultured; Cytokines; Glutamic Acid; Neuronal Plasticity; Neurons; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Wistar; Receptor Cross-Talk; Serine; Stress, Physiological | 2009 |
d-Serine modulates neurogenic relaxation in rat corpus cavernosum.
Topics: Animals; Brain; Gene Expression Regulation, Enzymologic; Glutamic Acid; Liver; Male; Muscle Relaxation; Penis; Racemases and Epimerases; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Serine | 2010 |
Neuroprotective effect of L-serine against temporary cerebral ischemia in rats.
Topics: Animals; Brain; Brain Ischemia; Cell Hypoxia; Cells, Cultured; Dose-Response Relationship, Drug; Glutamic Acid; Glycine Agents; Hippocampus; Infarction, Middle Cerebral Artery; Male; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Serine; Strychnine; Time Factors | 2010 |
Effect of amphetamine on extracellular concentrations of amino acids in striatum in neurotensin subtype 1 and 2 receptor null mice: a possible interaction between neurotensin receptors and amino acid systems for study of schizophrenia.
Topics: Amino Acids; Amphetamine; Animals; Central Nervous System Stimulants; Corpus Striatum; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Neurological; Receptors, Neurotensin; Schizophrenia; Serine | 2010 |
Activity of retinoic acid receptor-alpha is directly regulated at its protein kinase A sites in response to follicle-stimulating hormone signaling.
Topics: Animals; Binding Sites; Blotting, Western; Cell Nucleus; Cells, Cultured; Chlorocebus aethiops; COS Cells; Cyclic AMP-Dependent Protein Kinases; Follicle Stimulating Hormone; Glutamic Acid; Male; Mutation; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Receptors, FSH; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptor alpha; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Serine; Sertoli Cells; Signal Transduction | 2010 |
Ginsenoside Rg1 promotes glutamate release via a calcium/calmodulin-dependent protein kinase II-dependent signaling pathway.
Topics: Analysis of Variance; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Central Nervous System Agents; Dose-Response Relationship, Drug; Down-Regulation; Embryo, Mammalian; Ginsenosides; Glutamic Acid; Hippocampus; Mice; Mice, Inbred C57BL; Neurons; Phosphorylation; Protein Kinase Inhibitors; Serine; Signal Transduction; Sulfonamides; Synapsins | 2010 |
Glutamate 90 at the luminal ion gate of sarcoplasmic reticulum Ca2+-ATPase is critical for Ca(2+) binding on both sides of the membrane.
Topics: Animals; Binding Sites; Calcium; Databases, Protein; Glutamic Acid; Intracellular Membranes; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Protein Conformation; Rabbits; Recombinant Proteins; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine | 2010 |
Neuron-astrocyte interactions in the medial nucleus of the trapezoid body.
Topics: Amino Acid Transport System X-AG; Animals; Anthozoa; Astrocytes; Brain Stem; Calcium; Cell Communication; Chelating Agents; Electric Stimulation; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Glutamic Acid; Green Fluorescent Proteins; Membrane Potentials; Mice; Mice, Transgenic; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Serine; Synapses; Synaptic Transmission; Time Factors | 2010 |
AMPA GluR-A receptor subunit mediates hippocampal responsiveness in mice exposed to stress.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cytoskeletal Proteins; Glucocorticoids; Glutamic Acid; Hippocampus; Mice; Mice, Knockout; Nerve Tissue Proteins; Phosphorylation; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Serine; Stress, Physiological; Synapsins; Synaptic Transmission | 2011 |
Enzymatic synthesis of some (15)N-labelled L-amino acids.
Topics: Alanine Dehydrogenase; Amino Acids; Biocatalysis; Enzymes; Glucose 1-Dehydrogenase; Glutamate Dehydrogenase; Glutamic Acid; Isotope Labeling; Keto Acids; Leucine Dehydrogenase; Mass Spectrometry; Methionine; NAD; Nitrogen Isotopes; Serine | 2010 |
The major determinant of exendin-4/glucagon-like peptide 1 differential affinity at the rat glucagon-like peptide 1 receptor N-terminal domain is a hydrogen bond from SER-32 of exendin-4.
Topics: Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Cell Line; Exenatide; Glucagon-Like Peptide-1 Receptor; Glutamic Acid; Humans; Hydrogen Bonding; Hypoglycemic Agents; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Peptides; Protein Conformation; Protein Structure, Tertiary; Radioligand Assay; Rats; Receptors, Glucagon; Recombinant Proteins; Serine; Structure-Activity Relationship; Transfection; Venoms | 2010 |
NMDA receptors regulate GABAA receptor lateral mobility and clustering at inhibitory synapses through serine 327 on the γ2 subunit.
Topics: Amino Acid Substitution; Animals; Calcineurin; Calcium Signaling; Cells, Cultured; Glutamic Acid; Multiprotein Complexes; Mutagenesis, Site-Directed; Neuronal Plasticity; Neurons; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Serine; Signal Transduction; Synapses; Transfection | 2010 |
The structure and mechanism of the Mycobacterium tuberculosis cyclodityrosine synthetase.
Topics: Biocatalysis; Catalytic Domain; Crystallography, X-Ray; Cyclization; Dipeptides; Esterification; Glutamic Acid; Models, Molecular; Mycobacterium tuberculosis; Peptide Synthases; Peptides, Cyclic; Protein Conformation; RNA, Transfer, Tyr; Serine; Tyrosine; Tyrosine-tRNA Ligase | 2010 |
Acquisition of Raman spectra of amino acids using portable instruments: outdoor measurements and comparison.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; beta-Alanine; Glutamic Acid; Glutamine; Glycine; Methionine; Proline; Research Design; Robotics; Serine; Spectrum Analysis, Raman; Transportation; Tryptophan; Tyrosine; Workplace | 2010 |
A novel balanced chromosomal translocation found in subjects with schizophrenia and schizotypal personality disorder: altered l-serine level associated with disruption of PSAT1 gene expression.
Topics: Age of Onset; Animals; Astrocytes; Blotting, Western; Chromatography, High Pressure Liquid; Chromosomes, Human, Pair 9; Female; Gene Expression; Gene Knockdown Techniques; Glutamic Acid; Humans; Male; Middle Aged; Pedigree; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Schizophrenia; Serine; Transaminases; Translocation, Genetic; Young Adult | 2011 |
Probing the active site of the deoxynucleotide N-hydrolase Rcl encoded by the rat gene c6orf108.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Catalysis; Catalytic Domain; Glutamic Acid; Kinetics; Molecular Sequence Data; N-Glycosyl Hydrolases; Nuclear Proteins; Protein Binding; Proto-Oncogene Proteins; Rats; Sequence Homology, Amino Acid; Serine | 2010 |
Acute stress induces contrasting changes in AMPA receptor subunit phosphorylation within the prefrontal cortex, amygdala and hippocampus.
Topics: Amygdala; Animals; Brain Mapping; Cognition Disorders; Corticosterone; Frontal Lobe; Glutamic Acid; Hippocampus; Immunoassay; Long-Term Potentiation; Male; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Serine | 2010 |
PDZK1 binding and serine phosphorylation regulate subcellular trafficking of organic anion transport protein 1a1.
Topics: Adenosine Triphosphate; Alanine; Animals; Carrier Proteins; Cell Line, Tumor; Cell Membrane; Cytoplasmic Vesicles; Glutamic Acid; HEK293 Cells; Hepatocytes; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Mutagenesis, Site-Directed; Mutation; Organic Anion Transporters; Phosphorylation; Protein Binding; Protein Transport; Rats; Recombinant Fusion Proteins; Serine; Time Factors; Transfection | 2011 |
[Development of psychotropic agents for schizophrenia based on the glutamate hypothesis].
Topics: Animals; Disease Models, Animal; Drug Discovery; Glutamic Acid; Humans; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Serine | 2010 |
Post-translational phosphorylation of serine 74 of human deoxycytidine kinase favors the enzyme adopting the open conformation making it competent for nucleoside binding and release.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Biocatalysis; Deoxycytidine Kinase; Glutamic Acid; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Nucleosides; Phosphorylation; Protein Binding; Protein Conformation; Protein Processing, Post-Translational; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine | 2011 |
EMILiO: a fast algorithm for genome-scale strain design.
Topics: Algorithms; Escherichia coli; Genetic Engineering; Genome-Wide Association Study; Genome, Bacterial; Glutamic Acid; Serine; Succinic Acid | 2011 |
Effect of the quality of dietary amino acids composition on the urea synthesis in rats.
Topics: Alanine; Amino Acids; Animals; Caseins; Dietary Proteins; Egg Proteins; Glutamates; Glutamic Acid; Glutens; Liver; Male; Methionine; Ornithine; Protein Biosynthesis; Rats; Rats, Wistar; Serine; Urea | 2011 |
Covalent enzyme immobilization by poly(ethylene glycol) diglycidyl ether (PEGDE) for microelectrode biosensor preparation.
Topics: Amino Acid Oxidoreductases; Animals; Biosensing Techniques; Brain Chemistry; Cross-Linking Reagents; D-Amino-Acid Oxidase; Enzymes, Immobilized; Epoxy Resins; Fixatives; Glucose; Glucose Oxidase; Glutamic Acid; Glutaral; Male; Rats; Rats, Wistar; Serine | 2011 |
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genomics; Glutamic Acid; Humans; Ketoglutaric Acids; Melanoma; Mice; Neoplasm Transplantation; Phosphoglycerate Dehydrogenase; RNA Interference; Serine | 2011 |
Clozapine, but not haloperidol, enhances glial D-serine and L-glutamate release in rat frontal cortex and primary cultured astrocytes.
Topics: Animals; Antipsychotic Agents; Astrocytes; Cells, Cultured; Citrates; Clozapine; Glutamic Acid; Haloperidol; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Tetanus Toxin; Tetrodotoxin | 2012 |
Immunogold detection of L-glutamate and D-serine in small synaptic-like microvesicles in adult hippocampal astrocytes.
Topics: Animals; Astrocytes; Cells, Cultured; Glutamic Acid; Gold; Hippocampus; Immunohistochemistry; Rats; Rats, Wistar; Serine; Synaptic Vesicles | 2012 |
Overexpression of serine racemase in retina and overproduction of D-serine in eyes of streptozotocin-induced diabetic retinopathy.
Topics: Animals; Aqueous Humor; Blood Glucose; Body Weight; Cell Death; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glutamic Acid; JNK Mitogen-Activated Protein Kinases; Racemases and Epimerases; Random Allocation; Rats; Rats, Sprague-Dawley; Retina; Serine; Streptozocin | 2011 |
Pseudohyperphosphorylation has differential effects on polymerization and function of tau isoforms.
Topics: Amino Acid Substitution; Arachidonic Acid; Aspartic Acid; Biopolymers; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mutagenesis, Site-Directed; Phosphorylation; Protein Isoforms; Serine; tau Proteins; Tauopathies; Threonine | 2011 |
Coactivation of NMDA receptors by glutamate and D-serine induces dilation of isolated middle cerebral arteries.
Topics: Animals; Blotting, Western; Cells, Cultured; Denervation; Dose-Response Relationship, Drug; Drug Synergism; Endothelial Cells; Endothelium, Vascular; Fluorescent Antibody Technique; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Middle Cerebral Artery; Myography; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; Serine; Stereoisomerism; Vasodilation | 2012 |
A liquid phase based C. elegans behavioral analysis system identifies motor activity loss in a nematode Parkinson's disease model.
Topics: Animals; Animals, Genetically Modified; Antiparkinson Agents; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Electronic Data Processing; Glutamic Acid; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Levodopa; Motor Activity; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine; Software | 2012 |
Dysfunctional astrocytic regulation of glutamate transmission in a rat model of depression.
Topics: Animals; Astrocytes; Depression; Disease Models, Animal; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hippocampus; Humans; In Vitro Techniques; Male; Nerve Tissue Proteins; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Recognition, Psychology; Serine; Sodium Channel Blockers; Statistics, Nonparametric; Swimming; Synaptic Transmission; Tetrodotoxin | 2013 |
Timing-dependent reduction in ethanol sedation and drinking preference by NMDA receptor co-agonist d-serine.
Topics: Alcohol Drinking; Alcoholic Intoxication; Analysis of Variance; Animals; Ethanol; Glutamic Acid; Glycine; Male; Mice; Motor Activity; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Serine; Time Factors | 2012 |
Neuronal D-serine regulates dendritic architecture in the somatosensory cortex.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Coloring Agents; Dendrites; Dendritic Spines; Genotype; Glutamic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuronal Plasticity; Neurons; Post-Synaptic Density; Pyramidal Cells; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Serine; Somatosensory Cortex | 2012 |
mTOR pathway overactivation in BRAF mutated papillary thyroid carcinoma.
Topics: Amino Acid Substitution; Carcinoma; Carcinoma, Papillary; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glutamic Acid; HEK293 Cells; Humans; Mutation, Missense; Proto-Oncogene Proteins B-raf; Serine; Signal Transduction; Thyroid Cancer, Papillary; Thyroid Neoplasms; TOR Serine-Threonine Kinases; Transfection; Up-Regulation; Valine | 2012 |
TCN 201 selectively blocks GluN2A-containing NMDARs in a GluN1 co-agonist dependent but non-competitive manner.
Topics: Algorithms; Animals; Cerebral Cortex; Electrophysiological Phenomena; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Neurons; Oocytes; Patch-Clamp Techniques; Plasmids; Rats; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; RNA, Complementary; Serine; Sulfonamides; Transfection; Xenopus laevis | 2012 |
Protein phosphatase-1M and Rho-kinase affect exocytosis from cortical synaptosomes and influence neurotransmission at a glutamatergic giant synapse of the rat auditory system.
Topics: Animals; Animals, Newborn; Calcium; Cardiac Myosins; Cerebral Cortex; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Exocytosis; Female; Glutamic Acid; Immunoprecipitation; In Vitro Techniques; Male; Mass Spectrometry; Microscopy, Electron, Transmission; Myosin Light Chains; Patch-Clamp Techniques; Phosphorylation; Protein Binding; Protein Phosphatase 1; Qa-SNARE Proteins; Rats; Rats, Wistar; rho-Associated Kinases; Serine; Synapses; Synapsins; Synaptic Transmission; Synaptosomes; Threonine | 2012 |
Glutamate transporter-dependent mTOR phosphorylation in Müller glia cells.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Calcimycin; Calcium; Cells, Cultured; Chick Embryo; D-Aspartic Acid; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Ependymoglial Cells; Excitatory Amino Acid Agents; Gene Expression Regulation; Glutamic Acid; Phosphorylation; Retina; Serine; Signal Transduction; TOR Serine-Threonine Kinases | 2012 |
ONO-2506 inhibits spike-wave discharges in a genetic animal model without affecting traditional convulsive tests via gliotransmission regulation.
Topics: Animals; Anticonvulsants; Astrocytes; Caprylates; Cells, Cultured; Convulsants; Disease Models, Animal; Electroshock; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Kynurenic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pentylenetetrazole; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Serine; Synaptic Transmission | 2013 |
Activity-dependent modulation of the interaction between CaMKIIα and Abi1 and its involvement in spine maturation.
Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphate; Animals; Calcium; Calcium Chloride; Calcium Ionophores; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Catalytic Domain; Cells, Cultured; Cerebral Cortex; Dendritic Spines; Embryo, Mammalian; Excitatory Amino Acid Agents; Glucose Transporter Type 1; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Humans; Immunoprecipitation; Iodine Isotopes; Ionomycin; N-Methylaspartate; Neurons; Phosphorylation; Protein Binding; Qa-SNARE Proteins; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Serine; SNARE Proteins; Synapses; Transfection; Vesicular Glutamate Transport Protein 1 | 2012 |
TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory.
Topics: Analysis of Variance; Animals; Brain; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cyclin-Dependent Kinase 5; Dendritic Spines; Disks Large Homolog 4 Protein; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Green Fluorescent Proteins; Guanine Nucleotide Exchange Factors; Guanylate Kinases; Humans; Immunoprecipitation; In Vitro Techniques; Long-Term Potentiation; Maze Learning; Membrane Proteins; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Neurons; Phosphorylation; Quinoxalines; rac1 GTP-Binding Protein; Rats; Receptor, trkB; Ribosomal Protein S6 Kinases; Serine; Silver Staining; Spatial Behavior; Synaptophysin; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Time Factors; Transfection | 2012 |
Natural templates for coiled-coil biomaterials from praying mantis egg cases.
Topics: Alanine; Amino Acid Sequence; Animals; Biocompatible Materials; Biomimetic Materials; Circular Dichroism; Escherichia coli; Female; Fibroins; Gene Library; Glutamic Acid; Hydrophobic and Hydrophilic Interactions; Lysine; Magnetic Resonance Spectroscopy; Mantodea; Molecular Sequence Data; Molecular Weight; Ovum; Protein Structure, Secondary; Recombinant Proteins; Scleroproteins; Sequence Alignment; Sequence Analysis, DNA; Serine | 2012 |
Amino acid turnover by human oocytes is influenced by gamete developmental competence, patient characteristics and gonadotrophin treatment.
Topics: Age Factors; Alanine; Amino Acids; Arginine; Chorionic Gonadotropin; Chromatography, High Pressure Liquid; Female; Follicle Stimulating Hormone; Glutamic Acid; Glutamine; Gonadotropins; Humans; Infertility, Female; Isoleucine; Kinetics; Lysine; Metaphase; Oocytes; Ovulation Induction; Polycystic Ovary Syndrome; Serine; Valine | 2013 |
Endogenous activation of presynaptic NMDA receptors enhances glutamate release from the primary afferents in the spinal dorsal horn in a rat model of neuropathic pain.
Topics: Animals; Behavior, Animal; Excitatory Postsynaptic Potentials; Glutamic Acid; Ligation; Male; N-Methylaspartate; Neuralgia; Posterior Horn Cells; Protein Kinase C; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Spinal Nerves; Synapses | 2013 |
Molecular determinants for functional differences between alanine-serine-cysteine transporter 1 and other glutamate transporter family members.
Topics: Amino Acid Substitution; Amino Acid Transport System ASC; Animals; Archaeal Proteins; Aspartic Acid; Binding Sites; Biological Transport; Cells, Cultured; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Kinetics; Membrane Potentials; Mutagenesis, Site-Directed; Serine; Substrate Specificity; Xenopus laevis | 2013 |
The CAMKK2-AMPK kinase pathway mediates the synaptotoxic effects of Aβ oligomers through Tau phosphorylation.
Topics: Action Potentials; AMP-Activated Protein Kinase Kinases; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Cells, Cultured; Dendritic Spines; Dose-Response Relationship, Drug; Electroporation; Embryo, Mammalian; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glutamic Acid; Green Fluorescent Proteins; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurons; Patch-Clamp Techniques; Peptide Fragments; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinases; Serine; tau Proteins; Transfection | 2013 |
Cerebral ischemic injury is enhanced in a model of oculodentodigital dysplasia.
Topics: Animals; Astrocytes; Brain Infarction; Brain Ischemia; Cell Death; Cells, Cultured; Connexin 43; Craniofacial Abnormalities; Disease Models, Animal; Enzyme Inhibitors; Eye Abnormalities; Foot Deformities, Congenital; Gap Junctions; Glutamic Acid; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurons; Serine; Syndactyly; Tooth Abnormalities | 2013 |
Glycine transporter 1 modulates GABA release from amacrine cells by controlling occupancy of coagonist binding site of NMDA receptors.
Topics: Amacrine Cells; Animals; Axons; Binding Sites; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fish Proteins; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Glycine Agents; Glycine Plasma Membrane Transport Proteins; Goldfish; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Serine; Strychnine | 2013 |
Fluoxetine and citalopram decrease microglial release of glutamate and D-serine to promote cortical neuronal viability following ischemic insult.
Topics: Animals; Brain Ischemia; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Citalopram; Coculture Techniques; Fluoxetine; Glutamic Acid; Interleukin-1beta; Isomerism; Microglia; Neurons; Nitric Oxide; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serine; Tumor Necrosis Factor-alpha | 2013 |
Bio-inspired band gap engineering of zinc oxide by intracrystalline incorporation of amino acids.
Topics: Amino Acids; Arginine; Biomimetic Materials; Crystallization; Cysteine; Feasibility Studies; Glutamic Acid; Microscopy, Electrochemical, Scanning; Nitrogen; Photoelectron Spectroscopy; Selenocysteine; Semiconductors; Serine; X-Ray Diffraction; Zinc Oxide | 2014 |
Molecular determinants of orexin receptor-arrestin-ubiquitin complex formation.
Topics: Amino Acid Sequence; Arrestin; DNA, Complementary; Glutamic Acid; HEK293 Cells; Humans; Inositol Phosphates; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Mutagenesis; Neuropeptides; Orexin Receptors; Orexins; Serine; Threonine; Ubiquitin | 2014 |
Transglycosylation of engineered cyclodextrin glucanotransferases as O-glycoligases.
Topics: Alanine; Escherichia coli; Gene Expression; Glucosides; Glucosyltransferases; Glutamic Acid; Glycosylation; Kinetics; Ligases; Mutagenesis, Site-Directed; Mutation; Protein Engineering; Serine | 2014 |
A microchip electrophoresis-mass spectrometric platform for fast separation and identification of enantiomers employing the partial filling technique.
Topics: Cell Line; Cells; Dihydroxyphenylalanine; Electrophoresis, Microchip; Glutamic Acid; Humans; Mass Spectrometry; Serine; Stereoisomerism | 2013 |
NMDA receptor activation antagonizes the NMDA antagonist-induced antianxiety effect in the elevated plus-maze test in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Binding Sites; Brain; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Ligands; Male; Maze Learning; Mice; N-Methylaspartate; Quinolones; Receptors, N-Methyl-D-Aspartate; Serine | 2013 |
A "SYDE" effect of hierarchical phosphorylation: possible relevance to the cystic fibrosis basic defect.
Topics: Amino Acid Sequence; Aspartic Acid; Casein Kinase II; Consensus Sequence; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dictyostelium; Glutamic Acid; Humans; Molecular Sequence Data; Phosphorylation; Protein Interaction Domains and Motifs; Serine; Tyrosine | 2014 |
Increased D-serine in the aqueous and vitreous humour in patients with proliferative diabetic retinopathy.
Topics: Aged; Aqueous Humor; Case-Control Studies; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Glutamic Acid; Humans; Male; Middle Aged; Retinal Neovascularization; Retrospective Studies; Serine; Vitreous Body | 2014 |
Novel antibody against a glutamic acid-rich human fibrinogen-like protein 2-derived peptide near Ser91 inhibits hfgl2 prothrombinase activity.
Topics: Amino Acid Sequence; Animals; Antibodies; Antibody Specificity; Cell Polarity; Cell Proliferation; Fibrinogen; Glutamic Acid; Human Umbilical Vein Endothelial Cells; Humans; Lymphocyte Activation; Male; Models, Molecular; Molecular Sequence Data; Partial Thromboplastin Time; Peptides; Prothrombin Time; Rabbits; Serine; T-Lymphocytes; Thromboplastin | 2014 |
Astroglial d-serine is the endogenous co-agonist at the presynaptic NMDA receptor in rat entorhinal cortex.
Topics: Animals; Astrocytes; Entorhinal Cortex; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine | 2014 |
The Glu²¹⁶/Ser²¹⁸ pocket is a major determinant of spermine oxidase substrate specificity.
Topics: Amino Acid Substitution; Animals; Catalytic Domain; Circular Dichroism; Glutamic Acid; Kinetics; Mice; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Plant Proteins; Polyamine Oxidase; Protein Conformation; Recombinant Proteins; Serine; Spermine; Substrate Specificity; Zea mays | 2014 |
Insulin treatment prevents the increase in D-serine in hippocampal CA1 area of diabetic rats.
Topics: Animals; Behavior, Animal; CA1 Region, Hippocampal; Diabetes Mellitus, Experimental; Glutamic Acid; Insulin, Long-Acting; Long-Term Potentiation; Male; Maze Learning; Racemases and Epimerases; Rats; Rats, Sprague-Dawley; Serine | 2015 |
Changes in plasma D-serine, L-serine, and glycine levels in treatment-resistant schizophrenia before and after clozapine treatment.
Topics: Adult; Antipsychotic Agents; Case-Control Studies; Clozapine; Female; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Schizophrenia; Serine; Stereoisomerism; Treatment Failure | 2014 |
Phosphorylation of HPV-16 E2 at serine 243 enables binding to Brd4 and mitotic chromosomes.
Topics: Anaphase; Animals; Aspartic Acid; Cell Cycle Proteins; Chlorocebus aethiops; COS Cells; DNA-Binding Proteins; Genome, Viral; Glutamic Acid; Glutamine; HEK293 Cells; Human papillomavirus 16; Humans; Metaphase; Mutation; Nuclear Proteins; Oncogene Proteins, Viral; Phenotype; Phosphorylation; Protein Binding; Serine; Transcription Factors | 2014 |
Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB.
Topics: Bacterial Proteins; Bacteriocins; Crystallography, X-Ray; Escherichia coli; Glutamic Acid; Hydro-Lyases; Lactococcus lactis; Membrane Proteins; Models, Molecular; Nisin; Phylogeny; Protein Structure, Tertiary; RNA, Transfer, Glu; Serine; Threonine | 2015 |
Markers of glutamate signaling in cerebrospinal fluid and serum from patients with bipolar disorder and healthy controls.
Topics: Adult; Bipolar Disorder; Female; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Serine | 2015 |
D-serine uptake and release in PC-12 cells measured by chiral microchip electrophoresis-mass spectrometry.
Topics: Amino Acid Transport System ASC; Animals; Electrophoresis, Microchip; Glutamic Acid; Glycine; Mass Spectrometry; Neurons; PC12 Cells; Potassium Chloride; Rats; Serine; Stereoisomerism | 2015 |
Neuronal serine racemase regulates extracellular D-serine levels in the adult mouse hippocampus.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Extracellular Space; Glutamic Acid; Glycine; Hippocampus; Mice, Knockout; Microdialysis; N-Methylaspartate; Neurons; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Serine; Taurine | 2015 |
Syntheses of some α-cyclic tripeptides as potential inhibitors for HMG-CoA Reductase.
Topics: Glutamic Acid; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Models, Molecular; Molecular Docking Simulation; Peptides, Cyclic; Serine | 2015 |
In Vitro Study of L-Glutamate and L-Glutamine Transport in Retinal Pericytes: Involvement of Excitatory Amino Acid Transporter 1 and Alanine-Serine-Cysteine Transporter 2.
Topics: Alanine; Amino Acid Transport System ASC; Animals; Aspartic Acid; Cysteine; Excitatory Amino Acid Transporter 1; Glutamic Acid; Glutamine; Ion Transport; Male; Minor Histocompatibility Antigens; Pericytes; Rats, Wistar; Retina; Serine | 2015 |
L-Amino Acids Elicit Diverse Response Patterns in Taste Sensory Cells: A Role for Multiple Receptors.
Topics: Animals; Arginine; Calcium; Glutamic Acid; Glutamine; Mice; Mice, Knockout; Serine; Taste; Taste Buds; Taste Perception; Toll-Like Receptor 3; Tongue | 2015 |
Alterations in the motor cortical and striatal glutamatergic system and D-serine levels in the bilateral 6-hydroxydopamine rat model for Parkinson's disease.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Glutamic Acid; Male; Motor Cortex; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Serine | 2015 |
Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation.
Topics: Amino Acyl-tRNA Synthetases; Animals; Antineoplastic Agents; Apoptosis; Biosynthetic Pathways; Cystine; Drug Resistance, Neoplasm; Gene Knockdown Techniques; Glutamic Acid; Humans; PC12 Cells; Piperazines; Rats; Reactive Oxygen Species; Serine; Signal Transduction | 2016 |
Glycogen Synthase Kinase 3β-mediated Phosphorylation in the Most C-terminal Region of Protein Interacting with C Kinase 1 (PICK1) Regulates the Binding of PICK1 to Glutamate Receptor Subunit GluA2.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cell Membrane; Chlorocebus aethiops; COS Cells; Cytoskeletal Proteins; Glutamic Acid; Glycogen Synthase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Immunoprecipitation; Molecular Sequence Data; Nuclear Proteins; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, AMPA; Sequence Homology, Amino Acid; Serine | 2015 |
Increased serum levels of serine enantiomers in patients with depression.
Topics: Adult; Biomarkers; Case-Control Studies; Depression; Female; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Serine; Stereoisomerism; Young Adult | 2016 |
A new target ligand Ser-Glu for PEPT1-overexpressing cancer imaging.
Topics: Animals; Apoptosis; Blotting, Western; Cell Proliferation; Dipeptides; Female; Flow Cytometry; Fluorescence; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Pancreatic Neoplasms; Peptide Transporter 1; Polymers; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Symporters; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
D-Serine and Glycine Differentially Control Neurotransmission during Visual Cortex Critical Period.
Topics: Animals; Glutamic Acid; Glycine; Long-Term Potentiation; Male; Neuronal Plasticity; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Synaptic Transmission; Visual Cortex | 2016 |
Single exposure to cocaine impairs aspartate uptake in the pre-frontal cortex via dopamine D1-receptor dependent mechanisms.
Topics: Adenylyl Cyclases; Animals; Aspartic Acid; Cocaine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Extracellular Space; Gene Expression; Glutamic Acid; Mice; Phosphorylation; Prefrontal Cortex; Receptors, Dopamine D1; Serine; Signal Transduction; Time Factors | 2016 |
On the Influence of the Protonation States of Active Site Residues on AChE Reactivation: A QM/MM Approach.
Topics: Acetylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Computer Simulation; Glutamic Acid; Histidine; Models, Chemical; Molecular Structure; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Protons; Quantum Theory; Serine | 2017 |
Deficits in the activity of presynaptic γ-aminobutyric acid type B receptors contribute to altered neuronal excitability in fragile X syndrome.
Topics: Aged; Aged, 80 and over; Animals; Behavior, Animal; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Phosphorylation; Receptors, GABA-B; RNA, Messenger; Serine; Signal Transduction; Synaptic Transmission | 2017 |
Enhanced astrocytic d-serine underlies synaptic damage after traumatic brain injury.
Topics: Animals; Astrocytes; Brain; Brain Injuries; Brain Injuries, Traumatic; Cells, Cultured; Gliosis; Glutamic Acid; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Neurons; Receptors, N-Methyl-D-Aspartate; Serine; Synapses | 2017 |
Alterations in glutamatergic signaling in the brain of dopamine supersensitivity psychosis and non-supersensitivity psychosis model rats.
Topics: Animals; Antipsychotic Agents; Brain; Dopamine; Glutamate Decarboxylase; Glutamic Acid; Glutamine; Haloperidol; Infusion Pumps, Implantable; Male; Psychotic Disorders; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine | 2017 |
Analysis of adsorption processes of dissolved organic matter (DOM) on ferrihydrite using surrogate organic compounds.
Topics: Adsorption; Ferric Compounds; Glutamic Acid; Humic Substances; Kinetics; Models, Theoretical; Molecular Weight; Resorcinols; Rivers; Serine; Tannins; Water Pollutants, Chemical; Water Purification | 2017 |
Contribution of Astroglial Cx43 Hemichannels to the Modulation of Glutamatergic Currents by D-Serine in the Mouse Prefrontal Cortex.
Topics: Animals; Astrocytes; Calcium Signaling; Cells, Cultured; Connexin 43; Female; Glutamic Acid; Male; Mice; Mice, Knockout; Mice, Transgenic; Neuronal Plasticity; Neurotransmitter Agents; Prefrontal Cortex; Serine; Synaptic Transmission | 2017 |
Astrocytic signaling supports hippocampal-prefrontal theta synchronization and cognitive function.
Topics: Animals; Astrocytes; Cognition; Cognition Disorders; Doxycycline; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Maze Learning; Mice; Mice, Transgenic; Models, Neurological; Neurons; Prefrontal Cortex; Recognition, Psychology; S100 Calcium Binding Protein beta Subunit; Serine; Signal Transduction; SNARE Proteins; Spatial Behavior; Theta Rhythm | 2017 |
A NMDA-receptor calcium influx assay sensitive to stimulation by glutamate and glycine/D-serine.
Topics: Calcium; Gene Expression; Glutamic Acid; Glycine; HEK293 Cells; Humans; Protein Binding; Protein Multimerization; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Serine | 2017 |
The Effects of One Amino Acid Substitutions at the C-Terminal Region of Thermostable L2 Lipase by Computational and Experimental Approach.
Topics: Amino Acid Substitution; Bacterial Proteins; Circular Dichroism; Enzyme Stability; Glutamic Acid; Isoleucine; Lipase; Molecular Dynamics Simulation; Protein Conformation; Recombinant Proteins; Serine; Temperature; Valine | 2018 |
N-Methyl-d-aspartate receptor co-agonist availability affects behavioral and neurochemical responses to cocaine: insights into comorbid schizophrenia and substance abuse.
Topics: Animals; Cocaine; Comorbidity; Dopamine; Dopamine Uptake Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Mice; Mice, Knockout; Microdialysis; Nucleus Accumbens; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Self Stimulation; Serine; Substance-Related Disorders | 2019 |
SRR intronic variation inhibits expression of its neighbouring SMG6 gene and protects against temporal lobe epilepsy.
Topics: Animals; Case-Control Studies; Cohort Studies; Computational Biology; Disease Models, Animal; Epilepsy, Temporal Lobe; Female; Gene Expression Regulation; Genes, Reporter; Genotype; Glutamic Acid; Hippocampus; Humans; Introns; Luciferases; Male; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Racemases and Epimerases; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Telomerase | 2018 |
XPlex: An Effective, Multiplex Cross-Linking Chemistry for Acidic Residues.
Topics: Algorithms; Aspartic Acid; Computational Biology; Cross-Linking Reagents; Esters; Glutamic Acid; Lysine; Mass Spectrometry; Proteins; Serine; Succinimides; Temperature | 2018 |
Amygdala levels of the GluA1 subunit of glutamate receptors and its phosphorylation state at serine 845 in the anterior hippocampus are biomarkers of ictal fear but not anxiety.
Topics: Adult; Amygdala; Anxiety; Anxiety Disorders; Biomarkers; Fear; Female; Glutamic Acid; Hippocampus; Humans; Long-Term Potentiation; Male; Neuronal Plasticity; Phosphorylation; Receptors, AMPA; Receptors, Glutamate; Seizures; Serine; Synaptic Transmission | 2020 |
Structure-function analyses reveal the mechanism of the ARH3-dependent hydrolysis of ADP-ribosylation.
Topics: Adenosine Diphosphate Ribose; ADP-Ribosylation; Amino Acid Sequence; Catalytic Domain; Crystallography, X-Ray; DNA Damage; DNA Repair; Glutamic Acid; Glycoside Hydrolases; HEK293 Cells; Humans; Hydrogen Bonding; Hydrolysis; Magnesium; Mutagenesis, Site-Directed; Protein Conformation; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship | 2018 |
A High-throughput Calcium-flux Assay to Study NMDA-receptors with Sensitivity to Glycine/D-serine and Glutamate.
Topics: Calcium; Glutamic Acid; Glycine; HEK293 Cells; Humans; Receptors, N-Methyl-D-Aspartate; Serine | 2018 |
Sucrose ingestion induces glutamate AMPA receptor phosphorylation in dorsal hippocampal neurons: Increased sucrose experience prevents this effect.
Topics: Animals; Feeding Behavior; Glutamic Acid; Hippocampus; Male; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Serine; Sucrose; Sweetening Agents; Time Factors | 2019 |
Bioformation of Volatile and Nonvolatile Metabolites by
Topics: Acetates; Alanine; Carbon; Glutamic Acid; Glycine; Isoleucine; Mannitol; Mannose; Phenylacetates; Phenylalanine; Phenylethyl Alcohol; Proline; Saccharomycopsis; Serine; Sugar Alcohols; Threonine; Time Factors | 2018 |
Seminal plasma amino acid profile in different breeds of chicken: Role of seminal plasma on sperm cryoresistance.
Topics: Alanine; Amino Acids; Animals; Chickens; Cryopreservation; DNA Fragmentation; Glutamic Acid; Glycine; In Situ Nick-End Labeling; Male; Semen; Serine; Spermatozoa; Valine | 2019 |
Gamma-band auditory steady-state response is associated with plasma levels of d-serine in schizophrenia: An exploratory study.
Topics: Adolescent; Adult; Case-Control Studies; Electroencephalography; Evoked Potentials, Auditory; Female; GABAergic Neurons; Gamma Rhythm; Glutamic Acid; Glutamine; Glycine; Humans; Male; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Young Adult | 2019 |
Leucine-rich repeat kinase 2 (LRRK2) inhibitors differentially modulate glutamate release and Serine935 LRRK2 phosphorylation in striatal and cerebrocortical synaptosomes.
Topics: Aminopyridines; Animals; Benzamides; Benzodiazepinones; Corpus Striatum; Dopamine; Exocytosis; Gene Knock-In Techniques; Glutamic Acid; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mice; Phosphorylation; Pyrimidines; Serine; Synaptosomes; Visual Cortex | 2019 |
The cystine/glutamate antiporter xCT is a key regulator of EphA2 S897 phosphorylation under glucose-limited conditions.
Topics: Amino Acid Transport System y+; Antiporters; Cell Line, Tumor; Cell Movement; Cell Survival; Cystine; Gene Expression Regulation, Neoplastic; Glioblastoma; Glucose; Glutamic Acid; Humans; MAP Kinase Signaling System; Phosphorylation; Reactive Oxygen Species; Receptor, EphA2; Serine | 2019 |
pH-dependent adsorption of α-amino acids, lysine, glutamic acid, serine and glycine, on TiO
Topics: Adsorption; Glutamic Acid; Glycine; Hydrogen-Ion Concentration; Lysine; Protein Corona; Serine; Titanium | 2019 |
Alteration in NMDAR-related amino acids in first episode psychosis.
Topics: Asparagine; Chromatography, Liquid; Female; Glutamic Acid; Glutamine; Humans; Hydroxyproline; Male; Mass Spectrometry; Proline; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Young Adult | 2019 |
Efficient production of glutathione with multi-pathway engineering in Corynebacterium glutamicum.
Topics: Corynebacterium glutamicum; Cysteine; Glutamic Acid; Glutathione; Glycine; Metabolic Engineering; Metabolic Networks and Pathways; Serine | 2019 |
D-glutamate, D-serine, and D-alanine differ in their roles in cognitive decline in patients with Alzheimer's disease or mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alanine; Alzheimer Disease; Behavioral Symptoms; Chromatography, Liquid; Cognition; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Diet; Female; Glutamic Acid; Hospitals, University; Humans; Male; Middle Aged; Neuropsychological Tests; Serine; Taiwan | 2019 |
Sociality deficits in serine racemase knockout mice.
Topics: Animals; Behavior, Animal; Choice Behavior; Glutamic Acid; Mice; Mice, Knockout; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Serine; Social Behavior; Vocalization, Animal | 2019 |
How [FeFe]-Hydrogenase Facilitates Bidirectional Proton Transfer.
Topics: Catalytic Domain; Chlamydomonas reinhardtii; Glutamic Acid; Hydrogen Bonding; Hydrogenase; Iron-Sulfur Proteins; Protons; Serine; Spectroscopy, Fourier Transform Infrared | 2019 |
Glutamic acid at position 152 and serine at position 191 are key residues required for the metallo-β-lactamase activity of NDM-7.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Glutamic Acid; Humans; Mutation; Serine | 2020 |
The impact of different mutations at arginine141 on the structure, subunit exchange dynamics and chaperone activity of Hsp16.3.
Topics: Alanine; Amino Acid Substitution; Arginine; Bacterial Proteins; Binding Sites; Chaperonins; Glutamic Acid; Hydrophobic and Hydrophilic Interactions; Lactalbumin; Lysine; Mycobacterium tuberculosis; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Structure, Tertiary; Protein Subunits; Serine; Static Electricity; Structure-Activity Relationship; Substrate Specificity; Thermodynamics | 2020 |
Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation.
Topics: Animals; Cell Polarity; Cell Proliferation; Gene Expression Regulation, Enzymologic; Genomics; Glutamic Acid; Glycine; Interleukin-4; Ketoglutaric Acids; Kinetics; Macrophages; Mechanistic Target of Rapamycin Complex 1; Mice, Inbred C57BL; Models, Biological; Phosphoglycerate Dehydrogenase; Principal Component Analysis; Serine; Tuberous Sclerosis Complex 2 Protein | 2020 |
Activation of Astroglial Connexin is Involved in Concentration-Dependent Double-Edged Sword Clinical Action of Clozapine.
Topics: Antipsychotic Agents; Astrocytes; Cell Membrane; Clozapine; Connexin 43; Glutamic Acid; Humans; Myocarditis; Schizophrenia; Serine; Valproic Acid | 2020 |
Prenatal expression of D-aspartate oxidase causes early cerebral D-aspartate depletion and influences brain morphology and cognitive functions at adulthood.
Topics: Animals; Brain; Cognition; D-Aspartate Oxidase; D-Aspartic Acid; Gene Knock-In Techniques; Glutamic Acid; Male; Mice; Morris Water Maze Test; Open Field Test; Prefrontal Cortex; Serine | 2020 |
Characterization hiPSC-derived neural progenitor cells and neurons to investigate the role of NOS1AP isoforms in human neuron dendritogenesis.
Topics: Adaptor Proteins, Signal Transducing; Cells, Cultured; Clozapine; Dendrites; Drug Evaluation, Preclinical; Fluphenazine; Gene Expression Regulation; Glutamic Acid; Haloperidol; Humans; Induced Pluripotent Stem Cells; Ion Channels; Nerve Tissue Proteins; Neural Stem Cells; Neurons; Oligopeptides; Patch-Clamp Techniques; Protein Isoforms; Schizophrenia; Serine | 2020 |
Alteration of cofactor specificity of the acrylyl-CoA reductase from Escherichia coli.
Topics: Amino Acid Substitution; Arginine; Aspartic Acid; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Mutagenesis, Site-Directed; NAD; NADP; Protein Engineering; Quinone Reductases; Serine; Substrate Specificity | 2021 |
l-α-aminoadipate causes astrocyte pathology with negative impact on mouse hippocampal synaptic plasticity and memory.
Topics: 2-Aminoadipic Acid; Adenosine Triphosphate; Animals; Astrocytes; Cells, Cultured; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; In Vitro Techniques; Injections, Intraventricular; Long-Term Potentiation; Male; Memory; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Serine; Synaptic Transmission | 2021 |
Social preference is maintained in mice with impaired startle reflex and glutamate/D-serine imbalance induced by chronic cerebral toxoplasmosis.
Topics: Animals; Behavior, Animal; Body Weight; Brain; Glutamic Acid; Hippocampus; Mental Disorders; Mice; Neurotransmitter Agents; Prefrontal Cortex; Reflex, Startle; Serine; Social Behavior; Toxoplasma; Toxoplasmosis, Cerebral | 2021 |
Phosphorylation of the conserved C-terminal domain of ribosomal P-proteins impairs the mode of interaction with plant toxins.
Topics: Glutamic Acid; Humans; Molecular Docking Simulation; Phosphoproteins; Phosphorylation; Protein Domains; Ribosomal Proteins; Ricin; Serine; Toxins, Biological; Trichosanthin | 2021 |
Derivation and Molecular Characterization of a Morphological Subpopulation of Human iPSC Astrocytes Reveal a Potential Role in Schizophrenia and Clozapine Response.
Topics: Adult; Antipsychotic Agents; Astrocytes; Clozapine; Female; Glutamic Acid; Humans; Induced Pluripotent Stem Cells; Male; Middle Aged; Schizophrenia; Serine | 2022 |
The Amino Acid-mTORC1 Pathway Mediates APEC TW-XM-Induced Inflammation in bEnd.3 Cells.
Topics: Amino Acid Transport Systems; Amino Acids; Animals; Bird Diseases; Blood-Brain Barrier; Cell Line; Disease Models, Animal; Endothelial Cells; Escherichia coli; Glutamic Acid; Inflammation; Mechanistic Target of Rapamycin Complex 1; Mice; Serine | 2021 |
Comparative Hydrophobic Core Dynamics Between Wild-Type Amyloid-β Fibrils, Glutamate-3 Truncation, and Serine-8 Phosphorylation.
Topics: Amyloid; Amyloid beta-Peptides; Glutamic Acid; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phosphorylation; Serine | 2022 |
Astrocytes Render Memory Flexible by Releasing D-Serine and Regulating NMDA Receptor Tone in the Hippocampus.
Topics: Animals; Astrocytes; Bestrophins; Glutamic Acid; Hippocampus; Humans; Mice; Receptors, N-Methyl-D-Aspartate; Serine | 2022 |
Astroglial gliotransmitters released via Cx43 hemichannels regulate NMDAR-dependent transmission and short-term fear memory in the basolateral amygdala.
Topics: Animals; Astrocytes; Basolateral Nuclear Complex; Connexin 43; Fear; Glutamic Acid; Male; Memory, Short-Term; Neurons; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine | 2022 |
Prevention of Arterial Elastocalcinosis: Differential Roles of the Conserved Glutamic Acid and Serine Residues of Matrix Gla Protein.
Topics: Alanine; Animals; Calcium-Binding Proteins; Extracellular Matrix Proteins; Glutamic Acid; Matrix Gla Protein; Mice; Serine; Vascular Calcification; X-Ray Microtomography | 2022 |
Phosphorylation of serine residues S252, S268/S269, and S879 in p120 catenin activates migration of presomitic mesoderm in gastrulating zebrafish embryos.
Topics: Animals; Cadherins; Catenins; Glutamic Acid; Mesoderm; Mice; Phosphorylation; Serine; Threonine; Zebrafish | 2022 |
Characterization of Animal Protein-Based Binders in Ancient Chinese Wall Paintings Using Atomic Force Microscopy and Fourier Transform Infrared Spectroscopy.
Topics: Animals; Aspartic Acid; Bone Cements; Cattle; China; Female; Glutamic Acid; Microscopy, Atomic Force; Paintings; Proteins; Serine; Sheep; Spectroscopy, Fourier Transform Infrared | 2022 |
Gliotransmission of D-serine promotes thirst-directed behaviors in Drosophila.
Topics: Animals; Astrocytes; Drosophila; Glutamic Acid; N-Methylaspartate; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission; Thirst; Water | 2022 |
Multiomics assessment of dietary protein titration reveals altered hepatic glucose utilization.
Topics: Animals; Aspartic Acid; Dietary Proteins; Gluconeogenesis; Glucose; Glutamic Acid; Glycerol; Liver; Mice; Serine | 2022 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
The Metabolomic Approach for the Screening of Endometrial Cancer: Validation from a Large Cohort of Women Scheduled for Gynecological Surgery.
Topics: Early Detection of Cancer; Endometrial Neoplasms; Female; Glutamic Acid; Glyceraldehyde 3-Phosphate; Gynecologic Surgical Procedures; Humans; Phenylalanine; Serine | 2022 |
NMR-Based Metabolomic Analysis of Cardiac Tissues Clarifies Molecular Mechanisms of CVB3-Induced Viral Myocarditis and Dilated Cardiomyopathy.
Topics: Alanine; Animals; Aspartic Acid; Biomarkers; Cardiomyopathy, Dilated; Coxsackievirus Infections; Enterovirus B, Human; Glutamic Acid; Glutamine; Glycine; Mice; Mice, Inbred BALB C; Myocarditis; Niacin; Niacinamide; Serine; Taurine; Threonine | 2022 |
Formation and reduction of furan in pumpkin puree by precursors, antioxidants, sterilization and reheating.
Topics: Alanine; alpha-Linolenic Acid; Antioxidants; Ascorbic Acid; beta Carotene; Butylated Hydroxytoluene; Chlorogenic Acid; Cucurbita; Fructose; Furans; Glucose; Glutamic Acid; Linoleic Acid; Quercetin; Serine; Sterilization; Water | 2023 |
A Single Nucleotide Polymorphism Translates into a Radical Amino Acid Substitution at the Ligand-Binding Site in
Topics: Amino Acid Substitution; Animals; Anthelmintics; Binding Sites; Carboxylesterase; Esters; Fasciola hepatica; Glutamic Acid; Ligands; Lysine; Polymorphism, Single Nucleotide; Serine; Xenobiotics | 2022 |
Excitatory and inhibitory D-serine binding to the NMDA receptor.
Topics: Glutamic Acid; Molecular Conformation; Molecular Dynamics Simulation; Receptors, N-Methyl-D-Aspartate; Serine | 2022 |
An astrocytic signaling loop for frequency-dependent control of dendritic integration and spatial learning.
Topics: Animals; Astrocytes; CA1 Region, Hippocampal; Dendrites; Glutamic Acid; Mice; Pyramidal Cells; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Spatial Learning | 2022 |
Metabolomics profiling of seminal plasma in obesity-induced asthenozoospermia.
Topics: Aconitic Acid; Alanine; Asthenozoospermia; Citrulline; Glucose; Glutamic Acid; Glycine; Humans; Leucine; Lysine; Male; Metabolomics; Phenylalanine; Proline; Semen; Serine; Succinic Acid; Threonine; Tyrosine; Valine | 2023 |
Structural insights into the ligand binding domain of GluD1 and GluD2 receptors.
Topics: Glutamic Acid; Ligands; Protein Domains; Receptors, Glutamate; Serine | 2023 |
An evolutionarily nascent architecture underlying the formation and emergence of biomolecular condensates.
Topics: Biomolecular Condensates; Cell Nucleolus; Glutamic Acid; Protein Domains; Serine | 2023 |
The effects of the NMDAR co-agonist D-serine on the structure and function of optic tectal neurons in the developing visual system.
Topics: Animals; Glutamic Acid; Neurons; Receptors, N-Methyl-D-Aspartate; Serine; Superior Colliculi; Tectum Mesencephali | 2023 |