Compounds > serine

serine and geldanamycin

serine has been researched along with geldanamycin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Basu, A; Haldar, S1
Baker, JE; Pritchard, KA; Shi, Y; Su, J; Tweddell, JS; Zhang, C1
Lee, YS; Marcu, MG; Neckers, L1
Matts, RL; Yun, BG1
Birzin, ET; Chen, F; Chen, HY; Dininno, F; Fisher, JE; Freedman, LP; Hammond, ML; Kim, S; Lipfert, L; Reszka, AA; Rodan, GA; Rohrer, SP; Scafonas, A; Schmidt, A; Su, Q; Tan, Q; Warrier, S; Wei, N; Yudkovitz, J1
Barndt, RJ; Cheema, AK; Coticchia, CM; Deb, TB; Johnson, MD; Sengupta, S; Wang, Y; Zuo, AH1
Fujimuro, M; Kagawa, H; Mashino, T; Nakamura, S; Ohe, T; Ono, T; Ui, S; Watanabe, H; Watanabe, T; Yagi, S1

Other Studies

7 other study(ies) available for serine and geldanamycin

ArticleYear
Microtubule-damaging drugs triggered bcl2 phosphorylation-requirement of phosphorylation on both serine-70 and serine-87 residues of bcl2 protein.
    International journal of oncology, 1998, Volume: 13, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzoquinones; Binding Sites; Colchicine; Demecolcine; Enzyme Inhibitors; Gout Suppressants; Humans; Lactams, Macrocyclic; Microtubules; Mutagenesis, Site-Directed; Paclitaxel; Phosphorylation; Podophyllotoxin; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Quinones; Serine; Tumor Cells, Cultured

1998
Chronic hypoxia increases endothelial nitric oxide synthase generation of nitric oxide by increasing heat shock protein 90 association and serine phosphorylation.
    Circulation research, 2002, Aug-23, Volume: 91, Issue:4

    Topics: Animals; Animals, Newborn; Benzoquinones; Blotting, Western; Chronic Disease; Enzyme Activation; Enzyme Inhibitors; Fluorescent Dyes; HSP90 Heat-Shock Proteins; Hypoxia; In Vitro Techniques; Lactams, Macrocyclic; Myocardial Ischemia; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quinones; Rabbits; Recovery of Function; Serine; Superoxides; Ventricular Function, Left

2002
Quantum chemical calculations and mutational analysis suggest heat shock protein 90 catalyzes trans-cis isomerization of geldanamycin.
    Chemistry & biology, 2004, Volume: 11, Issue:7

    Topics: Adenosine Triphosphate; Benzoquinones; Catalysis; Crystallography, X-Ray; HSP90 Heat-Shock Proteins; Isomerism; Lactams, Macrocyclic; Quantum Theory; Quinones; Serine; Thermodynamics

2004
Hsp90 functions to balance the phosphorylation state of Akt during C2C12 myoblast differentiation.
    Cellular signalling, 2005, Volume: 17, Issue:12

    Topics: Animals; Benzoquinones; Cell Cycle Proteins; Cell Differentiation; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; HSP90 Heat-Shock Proteins; Lactams, Macrocyclic; Mice; Myoblasts; Novobiocin; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction

2005
Antagonist-induced, activation function-2-independent estrogen receptor alpha phosphorylation.
    Molecular endocrinology (Baltimore, Md.), 2006, Volume: 20, Issue:3

    Topics: Animals; Benzoquinones; Chlorocebus aethiops; COS Cells; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Cytoplasm; Endometrium; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Female; Fulvestrant; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Matrix Metalloproteinase 1; Organ Size; Phosphorylation; Promoter Regions, Genetic; Quinones; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Serine; Uterus

2006
Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex.
    American journal of physiology. Cell physiology, 2011, Volume: 300, Issue:5

    Topics: Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Inhibitors; ErbB Receptors; HEK293 Cells; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; Proteasome Endopeptidase Complex; Serine; Threonine

2011
Pyrrolidinium fullerene induces apoptosis by activation of procaspase-9 via suppression of Akt in primary effusion lymphoma.
    Biochemical and biophysical research communications, 2014, Aug-15, Volume: 451, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoquinones; Bridged-Ring Compounds; Caspase 9; Caspase Inhibitors; Cell Line, Tumor; Drug Screening Assays, Antitumor; Fullerenes; Herpesvirus 8, Human; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Lymphoma, Primary Effusion; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrrolidines; Serine; Virion

2014