serine has been researched along with folic acid in 177 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 121 (68.36) | 18.7374 |
| 1990's | 8 (4.52) | 18.2507 |
| 2000's | 16 (9.04) | 29.6817 |
| 2010's | 24 (13.56) | 24.3611 |
| 2020's | 8 (4.52) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, PY; Combepine, G; Cossins, EA | 1 |
| Canfield, CJ; McCormick, GJ; Smith, CC | 1 |
| Chanarin, I; Tikerpae, J | 1 |
| Laborit, H | 1 |
| Benkovic, SJ; Schirch, LV; Tatum, CM | 1 |
| Giliberti, P; Pignero, A; Tancredi, F | 1 |
| Cybulski, RL; Fisher, RR | 1 |
| Hems, R; Krebs, HA | 1 |
| Anderson, R; Jackson, N | 1 |
| Hsia, YE; Robertson, JS; Scully, KJ | 1 |
| Appling, DR; Laude, DA; Pasternack, LB | 1 |
| Bottiglieri, T; Chanarin, I; Deacon, R; Lumb, M; Perry, J | 1 |
| Appling, DR; Barlowe, CK | 1 |
| Boss, GR | 2 |
| Chanarin, I; Deacon, R; Lumb, M; Muir, M; Perry, J | 1 |
| Bruinvels, J; Fekkes, D | 1 |
| Dudman, NP; Tyrrell, PA; Wilcken, DE | 2 |
| Davis, RE; Icke, GC; Metz, J; van der Westhuyzen, J | 1 |
| Duffy, TH; Huennekens, FM; Vitols, KS | 1 |
| Altz-Smith, M; Baggott, JE; Morgan, SL | 1 |
| Shane, B; Stokstad, EL | 2 |
| Brattström, LE; Hardebo, JE; Hultberg, BL | 1 |
| Kikuchi, G; Yoshida, T | 3 |
| Frisell, WR; Randolph, VM | 1 |
| Paul, I; Wohllebe, W | 1 |
| Battesti, JP; Thuillier, A | 1 |
| Cossins, EA; Lor, KL | 1 |
| Murray, CL; Rabinowitz, JC; Samuel, CE | 1 |
| Beumer-Jochmans, MP; Godard, C | 1 |
| Harrap, KR; Jackson, RC | 1 |
| Beaton, JM; Bradley, RJ; Bridgers, WF; McClain, LD; Pegram, GV; Smythies, JR | 1 |
| Kikuchi, G; Kochi, H; Sato, N; Sato, T | 1 |
| Kung, HF; Wagner, C | 1 |
| Harris, B; Osmond, CB | 1 |
| Herman, RH; Rosensweig, NS; Stifel, FB | 3 |
| Poirier, LA | 1 |
| Battat, E; Goldberg, I; Mateles, RI | 1 |
| Gräser, H | 1 |
| Kikuchi, G; Kochi, H | 1 |
| Heinemann, M; Sloane, NH | 1 |
| Turner, JM; Willetts, AJ | 1 |
| Baerlocher, K; Giliberti, P; Matasović, A; Niederwieser, A; Pluznik, S; Steinmann, B | 1 |
| Decter, JB; Mansouri, A; Silber, R | 1 |
| Bridgers, WF; McClain, LD | 1 |
| Foster, MA; Pattison, JR; Salem, AR | 1 |
| Bovina, C; Marchetti, M; Rovinetti, C; Tolomelli, B | 2 |
| Ellegaard, J; Esmann, V | 3 |
| Chen, MS; Schirch, LV | 1 |
| Lewis, GP; Rowe, PB | 1 |
| Bird, HR; Shen, TF; Sunde, ML | 1 |
| Akrabawi, S; Daghir, NJ; Rabbani, A | 1 |
| Ellegaard, J; Esmann, V; Sölling, H | 1 |
| Barbiroli, B; Bovina, C; Marchetti, M; Tolomelli, B | 1 |
| Jackson, GJ; Platzer, EG | 1 |
| Bertino, JR; Hillcoat, BL | 1 |
| Corcino, JJ; Herbert, V; Waxman, S | 1 |
| Corcino, J; Herbert, V; Waxman, S | 1 |
| Dawes, J; Foster, MA | 1 |
| Arakawa, T; Narisawa, K; Ohara, K; Tamura, T; Tanno, K | 1 |
| Doi, RH; Migita, LK | 1 |
| D'Ari, L; Rabinowitz, JC; Samuel, CE | 1 |
| Lansing, AI; Lieberman, I; Pekarthy, JM; Short, J | 1 |
| Hutchison, DJ; Rader, JI | 1 |
| Cheyne, GA; Hytten, FE | 1 |
| DeGrazia, JA; Fish, MB; Hollander, L; Pollycove, M; Wallerstein, RO | 1 |
| Broderick, DS; Candland, KL; Mangum, JH; North, JA | 1 |
| Brown, KA; Ratledge, C | 1 |
| Bertino, JR; McCullough, JL; O'Brien, P | 1 |
| Bovina, C; Landi, L; Marchetti, M; Pasquali, P | 1 |
| Akhtar, M; Jordan, PM | 1 |
| Noronha, JM; Viswanathan, G | 1 |
| Bryan, RN; Hayashi, M | 1 |
| Foster, MA; Salem, AR; Wilson, RH | 1 |
| Biellmann, JF; Schuber, FJ | 1 |
| Diller, A; Schirch, LV | 1 |
| Aunio, R; Hakala, MT | 1 |
| Bridgers, WF | 1 |
| Fujioka, M | 1 |
| Knöfel, R; Müller, M; Rapoport, S | 1 |
| Allam, AM; Brill, WJ; Wolfe, RS; Wood, JM | 1 |
| Cossins, EA; Sinha, SK | 1 |
| Ropp, M; Schirch, L | 1 |
| Biellmann, JF; Schuber, F | 1 |
| Kikuchi, G; Kochi, H; Motokawa, Y; Sato, T | 1 |
| Appaji Rao, N; Rao, DN | 1 |
| Belousova, AK; Gerasimova, GK; Greshilov, MM; Vorontsov, IN | 2 |
| Bertino, JR; Cashmore, AR; Dreyer, RN; Moroson, BA; Scanlon, KJ | 1 |
| Dev, IK; Harvey, RJ | 1 |
| Wood, RC | 1 |
| Appling, DR; García-Martínez, LF | 1 |
| Schalinske, KL; Steele, RD | 1 |
| Appling, DR; Kastanos, E; Pasternack, LB; Woldman, YY | 1 |
| Appling, DR; Kastanos, EK; Woldman, YY | 1 |
| Cody, V; Queener, SF; Rosowsky, A | 1 |
| Cook, RJ | 1 |
| Baumgartner, TG; Cuskelly, GJ; Gregory, JF; Shane, B; Stacpoole, PW; Toth, JP | 1 |
| Berger, R; de Koning, TJ; Dorland, L; Duran, M; Jakobs, C; Poll-The, BT; Wevers, RA | 1 |
| Fowler, B | 1 |
| Jones, GM; Narkewicz, MR; Thompson, HR | 1 |
| Boss, GR; Chen, Y; Danishpajooh, IO; Gudi, T; Kharitonov, VG; Sharma, VS | 1 |
| Fennessey, PV; Jones, G; Kolhouse, F; Narkewicz, MR; Thompson, H | 1 |
| de Meer, K; Finglas, P; Smulders, Y; Stam, F; Stehouwer, CD; van den Akker, JT | 1 |
| Fowler, B; Kozich, V; Pristoupilová, K; Suormala, T; Zavad'áková, P; Zavadakova, P; Zeman, J | 1 |
| BLAKLEY, RL | 5 |
| CROSS, MJ; LASCELLES, J; WOODS, DD | 2 |
| LASCELLES, J; WOODS, DD | 1 |
| AWAPARA, J; DOCTOR, VM | 1 |
| AWAPARA, J; DOCTOR, VM; PATTON, TL | 1 |
| ANDERSON, ML; HERMAN, EC; WRIGHT, BE | 1 |
| DEWEY, VC; KIDDER, GW | 1 |
| FATTERPAKER, P; SREENIVASAN, A | 1 |
| HUTCHISON, DJ; JOHNSON, AH | 1 |
| MARCHETTI, M; MORUZZI, G; VIVIANI, R | 1 |
| LANGER, BW | 1 |
| SCHINDLER, R | 1 |
| AXELROD, LR; GOLDZIEHER, JW; MATTHIJSSEN, C; RAO, PN | 1 |
| ARNSTEIN, HR | 1 |
| KISLIUK, RL; SAKAMI, W | 1 |
| NEUMAN, RE; TYTELL, AA | 1 |
| MYERS, WF; PARETSKY, D | 1 |
| Bailey, LB; Coats, BS; Davis, SR; Gregory, JF; Kick, LS; Quinlivan, EP; Shane, B; Stacpoole, PW; Williamson, J | 1 |
| ELWYN, D; SPRINSON, DB | 1 |
| Bailey, LB; Capdevila, A; Coats, BS; Davis, SR; Ghandour, H; Gregory, JF; Quinlivan, EP; Selhub, J; Shane, B; Shelnutt, KP; Shuster, JJ; Stacpoole, PW; Wagner, C | 1 |
| Clausen, KO; Eek, AK; Hansteen, IL; Haugan, V; Skjelbred, CF; Svendsen, M; Svendsen, MV | 1 |
| Eggeling, L; Etterich, H; Faurie, R; Fersterra, H; Gerharz, T; Peters-Wendisch, P; Sahm, H; Stolz, M | 1 |
| Gregory, JF; Lam, SL; Nijhout, HF; Reed, MC; Shane, B; Ulrich, CM | 1 |
| Anderson, KS; Atreya, CE; Doan, LT; Martucci, WE; Vargo, MA | 1 |
| De Brouwer, V; Gambonnet, B; Lambert, WE; Loizeau, K; Ravanel, S; Rébeillé, F; Renou, JP; Van Der Straeten, D; Yu, A | 1 |
| Deng, L; Elmore, CL; Gupta, S; Knock, E; Kruger, W; Krupenko, N; Leclerc, D; Mohan, RD; Rozen, R; Tini, M; Wu, Q | 1 |
| Dou, W; Xu, H; Xu, Z; Zhang, X | 1 |
| Dikicioglu, D; Dunn, WB; Kell, DB; Kirdar, B; Oliver, SG | 1 |
| Liu, Y; Liu, YQ; Mori, M; Morita, T; Sugiyama, K | 1 |
| Hirata, A; Hori, H; Ishitani, R; Iwashita, C; Nishimasu, H; Nureki, O; Ochi, A; Tomikawa, C; Yamagami, R; Yamashita, K | 1 |
| Bertino, JR; Tedeschi, PM; Vazquez, A | 1 |
| Adarakis, G; Ardanaz, E; Boutron-Ruault, MC; Brennan, P; Bueno-de-Mesquita, B; Chirlaque, MD; Chuang, SC; de Magistris, MS; Dossus, L; Ericson, U; Eussen, SJ; Fredriksen, Å; Gallo, V; Grote, VA; Hustad, S; IJssennagger, N; Johansson, M; Meyer, K; Midttun, Ø; Nilsen, RM; Norat, T; Overvad, K; Peeters, PH; Perquier, F; Plada, M; Redondo, ML; Riboli, E; Ros, MM; Schneede, J; Sieri, S; Sonestedt, E; Teucher, B; Trichopoulou, A; Tumino, R; Ueland, PM; Ulvik, A; van Guelpen, B; Vineis, P; Vollset, SE; Wark, PA; Zamora-Ros, R | 1 |
| Bertino, JR; Boros, LG; Chan, LL; DiPaola, RS; Dolfi, SC; Dvorzhinski, D; Gounder, M; Hirshfield, KM; Lin, H; Markert, EK; Oltvai, ZN; Qiu, J; Tedeschi, PM; Vazquez, A | 1 |
| Fan, J; Kamphorst, JJ; Rabinowitz, JD; Shlomi, T; Thompson, CB; Ye, J | 1 |
| Dou, W; Li, H; Xu, G; Xu, Z; Zhang, X | 1 |
| Brosnan, JT; Brosnan, ME; Lamarre, SG; MacFarlane, AJ; MacMillan, L; Morrow, GP; Young, SK | 1 |
| Amornwatcharapong, W; Chaiyen, P; Chitnumsub, P; Krasatong, P; Leartsakulpanich, U; Maenpuen, S; Palfey, BA; Sucharitakul, J; Yuthavong, Y | 1 |
| Chu, SL; Ho, YL; Huang, PT; Liou, HH; Tsai, HJ; Yu, WH | 1 |
| Berge, RK; Bjørndal, B; Lysne, V; Nordrehaug, JE; Nygård, O; Skorve, J; Vik, R | 1 |
| Gopal, P; Madhusudana Reddy, T; Mohan Reddy, M; Narayana, PV; Ramakrishna Naidu, G | 1 |
| Baggott, JE; Tamura, T | 1 |
| Brosnan, JT; Brosnan, ME; MacMillan, L; Stevens, JR | 1 |
| Ahola, S; Battersby, BJ; Buzkova, J; Carroll, CJ; Chilov, D; Euro, L; Forsström, S; Isohanni, P; Khan, NA; Kohnz, RA; Liljenbäck, H; Lönnqvist, T; Marjamäki, P; Nikkanen, J; Nomura, DK; Paetau, A; Paetau, I; Pirnes-Karhu, S; Roivainen, A; Sajantila, A; Suomalainen, A; Terzioglu, M; Tyynismaa, H; Velagapudi, V; Viinamäki, J; Wang, L | 1 |
| Chen, L; Ducker, GS; Esposito, M; Ghergurovich, JM; Kang, Y; Morscher, RJ; Rabinowitz, JD; Teng, X | 1 |
| Asai, A; Doki, Y; Ishii, H; Kawamoto, K; Konno, M; Mori, M; Nishida, N; Satoh, T | 1 |
| Brewer, TF; Burgos-Barragan, G; Chang, CJ; Cordell, RL; Dingler, FA; Meiser, J; Monks, PS; Mulderrig, L; Patel, KJ; Pietzke, M; Pontel, LB; Rosado, IV; Vazquez, A; Wit, N | 1 |
| Brosnan, JT; Brosnan, ME; Clow, KA; MacMillan, L; Randell, EW; Tingley, G; Young, SK | 1 |
| Bushel, P; Chandel, N; Grenet, D; Li, J; Lozoya, OA; Martinez-Reyes, I; Santos, JH; Wang, T; Woychik, RP | 1 |
| Cahir-McFarland, E; Ersing, I; Gewurz, BE; Gygi, SP; Ma, Y; Mootha, VK; Nobre, L; Nomburg, J; Paulo, JA; Reinstadler, B; Shen, H; Smith, NA; Sommermann, T; Trudeau, S; Wang, LW; Wang, Z; Weekes, MP | 1 |
| Benjamin, SB; Drangowska-Way, A; Hilzendeger, MA; Joshi, C; Ke, W; Lewis, N; Locasale, J; Mony, VK; O'Rourke, EJ; Patti, GJ; Saba, JA; Yao, CH; Zhang, S | 1 |
| Dotsenko, O; Shtofel, D | 1 |
| Morellato, AE; Pontel, LB; Umansky, C | 1 |
| Elledge, SJ; Fang, Y; Gentili, M; Gewurz, BE; Guo, R; Hung, DT; Kim, SH; Leary, CNO; Liang, JH; Mootha, VK; Shah, H; Zhang, S; Zhang, Y | 1 |
| Hosokawa, S; Itoh, T; Narawa, T; Narita, Y | 1 |
| Clasquin, MF; Rabinowitz, JD; TeSlaa, T; Tesz, GJ; Xing, G; Xu, X; Yang, L; Zeng, X; Zhang, Z | 1 |
| Huang, X; Liang, S; Liu, R; Liu, X; Liu, Y; Yang, X; Zhao, J | 1 |
| Borowicz, PP; Caton, JS; Crouse, MS; Dahlen, CR; McLean, KJ; Neville, BW; Neville, TL; Reynolds, LP; Syring, JG; Ward, AK | 1 |
14 review(s) available for serine and folic acid
| Article | Year |
|---|---|
Folate status of patients on low-dose methotrexate therapy.
Topics: Folic Acid; Humans; Lymphocytes; Methotrexate; Serine | 1989 |
Cobalamin-folate interrelations: a critical review.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Megaloblastic; Animals; Central Nervous System; Deoxyuridine; Disease Models, Animal; Drug Interactions; Enzyme Activation; Folic Acid; Folic Acid Deficiency; Histidine; Humans; Liver; Methionine; Methylmalonyl-CoA Mutase; Nitrous Oxide; Oxidation-Reduction; Pteroylpolyglutamic Acids; Purines; Serine; Tetrahydrofolates; Thymidylate Synthase; Vitamin B 12; Vitamin B 12 Deficiency | 1985 |
Folic acid metabolism and its disruption by pharmacologic agents.
Topics: Folic Acid; Folic Acid Antagonists; Forecasting; Methionine; Purines; Serine; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase | 1987 |
Vitamin B12-folate interrelationships.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acids; Animals; Bone Marrow; Folic Acid; Folic Acid Deficiency; Formates; Formiminoglutamic Acid; Histidine; Homeostasis; Humans; Liver; Megaloblasts; Methionine; Methylation; Nitrous Oxide; Peptide Synthases; Pteroylpolyglutamic Acids; Purines; Serine; Thymidine Monophosphate; Thymidylate Synthase; Thyroid Gland; Vitamin B 12; Vitamin B 12 Deficiency | 1985 |
Some interrelationships of pyridoxal phosphate, folic acid, and serine metabolism in brain.
Topics: Animals; Brain; Cell Fractionation; Centrifugation, Density Gradient; Folic Acid; Mice; Mitochondria; Organ Size; Pyridoxal Phosphate; Rats; Serine; Synaptosomes; Transferases | 1972 |
Regulation of dihydrofolate reductase and other folate-requiring enzymes.
Topics: Alcohol Oxidoreductases; Animals; Enzyme Induction; Erythrocytes; Escherichia coli; Folic Acid; Folic Acid Antagonists; Formates; Guinea Pigs; Homocysteine; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Leukemia; Leukocytes; Ligases; Methotrexate; Oxidoreductases; Rats; Salmonella typhimurium; Serine; Streptococcus; Tetrahydrofolate Dehydrogenase | 1968 |
Drugs, toxins and dietary amino acids affecting vitamin B12 or folic acid absorption or utilization.
Topics: Amino Acids; Anemia, Macrocytic; Contraceptives, Oral; Diet; DNA; Ethanol; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Glycine; Homocysteine; Humans; Malabsorption Syndromes; Methionine; Pharmacology; Serine; Toxins, Biological; Vitamin B 12 | 1970 |
Aggravation or initiation of megaloblastosis by amino acids in the diet.
Topics: Amino Acids; Anemia, Pernicious; Cell Nucleus; Diet; DNA; Erythrocytes; Folic Acid; Folic Acid Deficiency; Glycine; Hematologic Diseases; Homocystine; Humans; Methionine; Polycythemia; Pyridoxine; Serine; Tetrahydrofolate Dehydrogenase; Thymine; Vitamin B 12; Vitamin B 12 Deficiency | 1970 |
The interrelationships among folate, vitamin B12, and methionine metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acids; Animals; DNA; Drug Interactions; Folic Acid; Formates; Histidine; Humans; Megaloblasts; Methionine; Nitrous Oxide; Peptide Synthases; Pteroylpolyglutamic Acids; Purines; Serine; Tetrahydrofolates; Thymidine Monophosphate; Thyroid Gland; Vitamin B 12 | 1983 |
The folate cycle and disease in humans.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5,10-Methylenetetrahydrofolate Reductase (FADH2); Aminohydrolases; Biological Transport, Active; Folic Acid; Formate-Tetrahydrofolate Ligase; Histidine; Homeostasis; Homocysteine; Humans; Intestinal Mucosa; Kidney Diseases; Metabolism, Inborn Errors; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Multienzyme Complexes; Oxidoreductases; Polyglutamic Acid; Purine Nucleotides; Serine; Tetrahydrofolates | 2001 |
In vivo stable isotope measurements of methyl metabolism: applications in pathophysiology and interventions.
Topics: Deuterium Oxide; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infusions, Intravenous; Kidney Failure, Chronic; Methionine; Methylation; Serine; Tomography, Emission-Computed; Tritium | 2002 |
Folate-Dependent Purine Nucleotide Biosynthesis in Humans.
Topics: Carbon; Circadian Rhythm; Folic Acid; Formates; Glycine; Humans; Leucovorin; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Phosphoribosylglycinamide Formyltransferase; Purine Nucleotides; Serine; Uric Acid | 2015 |
Division of labour: how does folate metabolism partition between one-carbon metabolism and amino acid oxidation?
Topics: Aldehyde Dehydrogenase; Amino Acids; Animals; Cytosol; Energy Metabolism; Folic Acid; Humans; Isoenzymes; Mitochondria; Models, Biological; Nutritional Requirements; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; S-Adenosylmethionine; Serine | 2015 |
The one-carbon metabolism pathway highlights therapeutic targets for gastrointestinal cancer (Review).
Topics: Aminohydrolases; Antineoplastic Agents; Fluorouracil; Folic Acid; Folic Acid Antagonists; Gastrointestinal Neoplasms; Glycine Hydroxymethyltransferase; Humans; Metabolic Networks and Pathways; Metabolome; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); MicroRNAs; Mitochondria; Molecular Targeted Therapy; Multienzyme Complexes; Nucleosides; Nucleotides; Oxidoreductases Acting on CH-NH Group Donors; Purines; Reactive Oxygen Species; Serine | 2017 |
2 trial(s) available for serine and folic acid
| Article | Year |
|---|---|
Effects of high-dose folic acid on protein metabolism in breast muscle and performance of broilers.
Topics: Animal Feed; Animals; Carbon; Chickens; Diet; Dietary Supplements; Folic Acid; Mammals; Myogenin; Pectoralis Muscles; Plant Breeding; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases; Serine; TOR Serine-Threonine Kinases | 2022 |
Concentrations of vitamin B12 and folate in maternal serum and fetal fluids, metabolite interrelationships, and hepatic transcript abundance of key folate and methionine cycle genes: the impacts of maternal nutrition during the first 50 d of gestation.
Topics: Animals; Carbon; Cattle; Diet; Female; Folic Acid; Glycine; Liver; Methionine; Pregnancy; Racemethionine; Serine; Vitamin B 12 | 2023 |
161 other study(ies) available for serine and folic acid
| Article | Year |
|---|---|
One-carbon metabolism in Neurospora crassa wild-type and in mutants partially deficient in serine hydroxymethyltransferase.
Topics: Alcohol Oxidoreductases; Amino Acids; Carbon; Folic Acid; Formate-Tetrahydrofolate Ligase; Formates; Glycine; Glycine Hydroxymethyltransferase; Methylenetetrahydrofolate Dehydrogenase (NADP); Mutation; Neurospora; Neurospora crassa; Serine; Species Specificity; Time Factors; Transferases | 1976 |
Plasmodium knowlesi: in vitro biosynthesis of methionine and thymidylic acid.
Topics: Animals; Betaine; Cells, Cultured; Choline; Erythrocytes; Folic Acid; Formaldehyde; Formyltetrahydrofolates; Haplorhini; Histidine; Homocysteine; Macaca mulatta; Methionine; Plasmodium; Sarcosine; Serine; Thymidine Monophosphate; Thymine Nucleotides | 1977 |
Folate-dependent serine synthesis in lymphocytes from controls and patients with megaloblastic anaemia: the effect of therapy.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Anemia, Pernicious; Folic Acid; Folic Acid Deficiency; Formates; Humans; In Vitro Techniques; Lymphocytes; Serine; Vitamin B 12; Vitamin B 12 Deficiency | 1978 |
[Role of folic acid in the physiology of the central nervous system].
Topics: Animals; Central Nervous System; Folic Acid; Glutamates; Glycine; Methylation; Purines; Rabbits; Serine | 1978 |
Serine transhydroxymethylase: evidence for a sequential random mechanism.
Topics: Animals; Folic Acid; Glycine; Glycine Hydroxymethyltransferase; Kinetics; Liver; Rabbits; Serine; Spectrophotometry; Threonine; Transferases | 1977 |
[Folic acid metabolism in Lesch-Nythan syndrome].
Topics: Folic Acid; Glycine; Histidine; Humans; Lesch-Nyhan Syndrome; Methionine; Serine | 1977 |
Intramitochondrial localization and proposed metabolic significance of serine transhydroxymethylase.
Topics: Animals; Azo Compounds; Benzenesulfonates; Digitonin; Folic Acid; Glycine; Glycine Hydroxymethyltransferase; Membranes; Mitochondria, Liver; Mitochondrial Swelling; Models, Biological; Rats; Serine; Tetrahydrofolates; Transferases | 1976 |
The regulation of the degradation of methionine and of the one-carbon units derived from histidine, serine and glycine.
Topics: Animals; Carbon Dioxide; Enzyme Activation; Folic Acid; Formates; Formiminoglutamic Acid; Gluconeogenesis; Glucose; Glycine; Histidine; Homocysteine; In Vitro Techniques; Liver; Methionine; Oxidoreductases Acting on CH-NH Group Donors; Perfusion; Rats; Serine; Tetrahydrofolates | 1976 |
A study on the effect of folate deficiency on the incorporation of 14-C labelled glycine, serine and leucine into the oviduct protein of the oestrogen-treated, immature female domestic fowl.
Topics: Animals; Chickens; Estradiol; Female; Folic Acid; Folic Acid Deficiency; Glycine; Leucine; Organ Size; Oviducts; Protein Biosynthesis; Serine; Time Factors | 1975 |
Defective leukocyte metabolism in human cobalamin deficiency: impaired propionate oxidation and serine biosynthesis reversible by cyanocobalamin therapy.
Topics: Adult; Aged; Anemia, Pernicious; Female; Folic Acid; Folic Acid Deficiency; Humans; Leukocyte Count; Leukocytes; Male; Middle Aged; Neutrophils; Propionates; Serine; Succinates; Vitamin B 12; Vitamin B 12 Deficiency | 1976 |
13C NMR detection of folate-mediated serine and glycine synthesis in vivo in Saccharomyces cerevisiae.
Topics: Aminohydrolases; Cytosol; Folic Acid; Formate-Tetrahydrofolate Ligase; Formates; Glycine; Isoenzymes; Magnetic Resonance Spectroscopy; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondria; Multienzyme Complexes; Saccharomyces cerevisiae; Serine | 1992 |
Methylthioadenosine serves as a single carbon source to the folate co-enzyme pool in rat bone marrow cells.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Bone Marrow; Carbon; Deoxyadenosines; Folic Acid; Formates; Glycine; Guanine; Male; Methionine; Methionine Adenosyltransferase; Oxidation-Reduction; Rats; Rats, Inbred Strains; Serine; Thionucleosides | 1990 |
In vitro evidence for the involvement of mitochondrial folate metabolism in the supply of cytoplasmic one-carbon units.
Topics: Animals; Cytosol; Folic Acid; Formates; Hypoxanthine; Hypoxanthines; Kinetics; Liver; Mitochondria, Liver; Rats; Rats, Inbred Strains; Sarcosine; Serine; Submitochondrial Particles | 1988 |
Cobalamin inactivation decreases purine and methionine synthesis in cultured lymphoblasts.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Folic Acid; Humans; Lymphocytes; Methionine; Methylmalonyl-CoA Mutase; Nitrous Oxide; Purines; Serine; Vitamin B 12 | 1985 |
Serine and folate metabolism in fibroblasts from episodic psychotic patients with psychedelic symptoms.
Topics: Aminohydrolases; Cystathionine beta-Synthase; Fibroblasts; Folic Acid; Formate-Tetrahydrofolate Ligase; Glycine Hydroxymethyltransferase; Humans; Kinetics; Methenyltetrahydrofolate Cyclohydrolase; Methylenetetrahydrofolate Dehydrogenase (NADP); Psychoses, Substance-Induced; Serine | 1986 |
Cobalamin inactivation decreases purine and methionine synthesis in cultured human lymphoblasts.
Topics: Folic Acid; Homocysteine; Humans; Lymphocytes; Methionine; Nitrous Oxide; Oxidation-Reduction; Purines; Serine; Vitamin B 12 | 1986 |
Homocysteinemia: depressed plasma serine levels.
Topics: Adult; Betaine; Carbon-Oxygen Lyases; Child, Preschool; Folic Acid; Glycine; Homocysteine; Humans; Isoleucine; Kidney Transplantation; Lyases; Male; Serine | 1987 |
Tissue folates in fruit bats (Rousettus aegyptiacus) with nitrous oxide-induced vitamin B12 deficiency and neurological impairment.
Topics: Animals; Brain; Chiroptera; Folic Acid; Liver; Methionine; Nervous System Diseases; Nitrous Oxide; Serine; Vitamin B 12 Deficiency | 1987 |
Folate status of rheumatoid arthritis patients receiving long-term, low-dose methotrexate therapy.
Topics: Adult; Arthritis, Rheumatoid; Diet; Erythrocytes; Female; Folic Acid; Humans; In Vitro Techniques; Leucovorin; Lymphocytes; Male; Methotrexate; Middle Aged; Serine; Vitamins | 1987 |
Folic acid responsive postmenopausal homocysteinemia.
Topics: Adult; Aging; Cystine; Dipeptides; Fasting; Female; Folic Acid; Glycine; Homocysteine; Humans; Male; Menopause; Methionine; Middle Aged; Serine | 1985 |
Homocystinuria due to cystathionine beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients.
Topics: Adolescent; Adult; Betaine; Child; Cystathionine beta-Synthase; Cysteine; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Homocystinuria; Humans; Hydro-Lyases; Male; Methionine; Middle Aged; Pyridoxine; Serine | 1985 |
Significance of the glycine cleavage system in glycine and serine catabolism in avian liver.
Topics: Ammonium Chloride; Animals; Arylformamidase; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Chickens; Columbidae; Cycloserine; Cysteine; Enzyme Activation; Folic Acid; Glycine; Hydroxylamines; Hypoxanthines; L-Serine Dehydratase; Liver; Male; Mitochondria, Liver; NAD; NADP; Oxidoreductases; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Semicarbazides; Serine; Species Specificity; Subcellular Fractions; Transferases; Uric Acid | 1971 |
Effect of adenine nucleotides on the oxidation of methyl groups in liver mitochondria.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Carbon Dioxide; Dinitrophenols; Folic Acid; Formaldehyde; Formates; Glycine; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methylation; Mitochondria, Liver; Mitochondrial Swelling; NAD; NADP; Oxygen Consumption; Rats; Rotenone; Sarcosine; Semicarbazides; Serine | 1973 |
[Report on a vitamin B 6 deficiency anemia].
Topics: Adult; Anemia, Sideroblastic; Folic Acid; Glycine; Humans; Male; Pyridoxine; Serine; Vitamin B 6 Deficiency | 1966 |
[Folic acid deficiencies. Etiology and biological diagnosis].
Topics: Alcoholic Intoxication; Anticonvulsants; Antimetabolites; Celiac Disease; Chromatography; Enterococcus faecalis; Female; FIGLU Test; Folic Acid; Folic Acid Deficiency; Humans; Jejunum; Lactobacillus; Liver Cirrhosis; Malabsorption Syndromes; Methionine; Methods; Nucleic Acids; Nutrition Disorders; Polarography; Pregnancy; Scleroderma, Systemic; Serine; Whipple Disease | 1968 |
Regulation of C metabolism by L-methionine in Saccharomyces cerevisiae.
Topics: Alcohol Oxidoreductases; Biological Assay; Carbon Isotopes; Cells, Cultured; Chromatography, DEAE-Cellulose; Culture Media; Folic Acid; Formates; Lacticaseibacillus casei; Ligases; Methionine; Methylation; Pediococcus; S-Adenosylmethionine; Saccharomyces cerevisiae; Serine; Tetrahydrofolates; Transferases | 1972 |
NH2-terminal amino acid distribution and amino acid composition of Streptococcus faecalis R soluble and ribosomal proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aspartic Acid; Autoanalysis; Bacterial Proteins; Cell-Free System; Culture Media; Dinitrophenols; Enterococcus faecalis; Folic Acid; Glutamates; Glycine; Methionine; Ribosomes; Serine; Solubility; Threonine | 1973 |
[Behavior of Shigella flexneri F6S and certain of its mutants in synthetic medium].
Topics: Amino Acids; Culture Media; Cysteine; Cystine; Folic Acid; Genetics, Microbial; Growth Substances; Methionine; Mutation; Niacinamide; Serine; Shigella; Temperature; Thiamine; Vitamin B 12 | 1971 |
Studies with a mathematical model of folate metabolism.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Floxuridine; Folic Acid; Formates; Glycine; Hydrolases; Kinetics; Leukemia L1210; Mathematics; Methotrexate; Models, Biological; Oxidoreductases; Pentosephosphates; Purines; Serine; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Thymidylate Synthase; Time Factors; Transferases | 1973 |
A study of the behavioral disruption of mice induced by l-methionine and related compounds.
Topics: Amphetamine; Animals; Behavior, Animal; Betaine; Chlorpromazine; Cystathionine; Folic Acid; Histidine; Homocysteine; Homoserine; Male; Mescaline; Methionine; Mice; N,N-Dimethyltryptamine; Niacinamide; Serine; Social Behavior | 1974 |
Glycine metabolism by rat liver mitochondria. 3. The glycine cleavage and the exchange of carboxyl carbon of glycine with bicarbonate.
Topics: Ammonia; Animals; Arsenic; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Folic Acid; Glycine; In Vitro Techniques; Kinetics; Mitochondria, Liver; NAD; Pyridoxal Phosphate; Rats; Serine; Sulfhydryl Compounds; Transferases | 1969 |
The enzymatic synthesis of N-methylalanine.
Topics: Adenosine Triphosphate; Alanine; Amines; Autoradiography; Carbon Isotopes; Chromatography, Gel; Chromatography, Thin Layer; Crystallization; Electrophoresis; Folic Acid; Glutamates; Magnesium; NAD; Paper; Pseudomonas; Pyruvates; Serine | 1970 |
Photorespiration during C 4 photosynthesis.
Topics: Alanine; Alcohol Oxidoreductases; Aldehyde-Lyases; Aspartic Acid; Carbohydrates; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Chromatography, Ion Exchange; Electrophoresis; Folic Acid; Fructose; Glycerophosphates; Glycine; Glycolates; Glyoxylates; Hexosephosphates; Ligases; Malates; Oxidoreductases; Pentosephosphates; Phosphoric Monoester Hydrolases; Phosphotransferases; Photosynthesis; Plants; Pyruvates; Ribose; Serine; Sulfites; Transferases | 1971 |
Dietary regulation of glycolytic enzymes. XI. Effect of inhibitors of protein synthesis on the adaptation of certain jejunal glycolytic and folate-metabolizing enzymes to diet and sex steroids.
Topics: Aldehyde-Lyases; Animals; Caseins; Dactinomycin; Dietary Carbohydrates; Dietary Proteins; Enzyme Induction; Estradiol; Ethionine; Fasting; Female; Folic Acid; Fructose; Fructosephosphates; Glycolysis; Jejunum; Male; Metabolism; NAD; Oxidoreductases; Pyruvate Kinase; Rats; RNA; Serine; Testosterone; Time Factors; Transferases | 1971 |
Folate deficiency in rats bearing the Walker tumor 256 and the Novikoff hepatoma.
Topics: Adenine; Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Choline; Diet; FIGLU Test; Folic Acid; Folic Acid Deficiency; Formates; Glycine; Guanine; Liver Neoplasms; Male; Methionine; Neoplasms, Experimental; Rats; Serine; Thymidine; Vitamin B 12 | 1973 |
Growth of Pseudomonas C on C1 compounds: continuoous culture.
Topics: Aminobenzoates; Carbon Dioxide; Carbon Radioisotopes; Folic Acid; Formaldehyde; Formates; Glycine; Methanol; NAD; Polysorbates; Pseudomonas; Serine | 1974 |
[The cofactors of serine synthesis in primary root homogenates of Zea mays].
Topics: Adenosine Triphosphate; Biotin; Buffers; Chromatography; Electrophoresis; Folic Acid; NADP; Poaceae; Pyridoxal Phosphate; Serine; Vitamin B 12 | 1966 |
Reactions of glycine synthesis and glycine cleavage catalyzed by extracts of Arthrobacter globiformis grown on glycine.
Topics: Ammonium Chloride; Arthrobacter; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Cell-Free System; Folic Acid; Formaldehyde; Glutathione; Glycine; Ion Exchange Resins; Kinetics; Mitochondria, Liver; NAD; NADP; Pyridoxal Phosphate; Serine; Sulfhydryl Compounds | 1969 |
Hydroxymethylation of the benzene ring. V. NADPH requirement for aryl hydroxymethylation by a C-1 donor bound to a macromolecule.
Topics: Animals; Ascorbic Acid; Benzene; Cell-Free System; Folic Acid; Guinea Pigs; Leucovorin; Microsomes, Liver; NADP; Phenols; Resins, Plant; Serine; Tritium; Vibration | 1970 |
Major pathways of glycine and serine catabolism in rat liver.
Topics: Adenosine Triphosphate; Animals; Carbon Dioxide; Carbon Isotopes; Chromatography, Ion Exchange; Folic Acid; Glycine; L-Serine Dehydratase; Liver; Male; Mitochondria, Liver; NADP; Oxidoreductases; Pyruvates; Rats; Serine; Spectrophotometry; Transferases | 1970 |
L-Threonine acetaldehyde-lyase in a strain of Bacillus subtilis.
Topics: Acetates; Aldehyde-Lyases; Bacillus subtilis; Carboxy-Lyases; Chromatography, Gel; Folic Acid; Glycine; Hydrazines; Hydrogen-Ion Concentration; Isoniazid; Kinetics; L-Serine Dehydratase; NAD; NADP; Phosphoric Acids; Pyridoxal Phosphate; Serine; Stereoisomerism; Threonine; Transferases | 1971 |
Folic acid non-dependent formiminoglutamic aciduria in two siblings.
Topics: Administration, Oral; Adult; Amides; Child, Preschool; Chromatography, Ion Exchange; Creatinine; Electrophoresis, Paper; Female; FIGLU Test; Folic Acid; Follow-Up Studies; Formates; Glutamates; Glycine; Hemoglobins; Histidine; Humans; Imidazoles; Imines; Intelligence Tests; Male; Mass Spectrometry; Pedigree; Serine; Transferases | 1974 |
Studies on the regulation of one-carbon metabolism. II. Repression-derepression of serine hydroxymethyltransferase by methionine in Escherichia coli 113-3.
Topics: Ammonium Sulfate; Chemical Precipitation; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Enzyme Repression; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Hydroxyapatites; Kinetics; Methionine; Methyltransferases; Molecular Weight; Oxidoreductases; S-Adenosylmethionine; Serine; Tetrahydrofolate Dehydrogenase; Thymine Nucleotides; Transferases; Uracil Nucleotides; Vitamin B 12 | 1972 |
Folic acid and the methylation of homocysteine by Bacillus subtilis.
Topics: Alcohol Oxidoreductases; Bacillus subtilis; Chromatography, Gel; Chromatography, Thin Layer; Cobamides; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Serine; Ultrasonics; Vitamin B 12 | 1972 |
[Mechanism of action of steroid hormones: 17 -estradiol, nucleic acids and folic coenzymes].
Topics: Animals; Castration; Coenzymes; Estradiol; Female; Folic Acid; Liver; Methyltransferases; Rats; Serine; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Uterus | 1972 |
Folate activity of human lymphocytes determined by measurement of serine synthesis.
Topics: Carbon Dioxide; Carbon Isotopes; Chromatography, Thin Layer; Citric Acid Cycle; Folic Acid; Folic Acid Deficiency; Formates; Glucose; Glycine; Humans; In Vitro Techniques; Lymphocytes; Methionine; Methods; Protein Binding; Pyridoxal Phosphate; RNA; Serine; Tetrahydrofolates | 1973 |
Serine transhydroxymethylase. A kinetic study of the synthesis of serine in the absence of tetrahydrofolate.
Topics: Acetaldehyde; Catalysis; Chemical Phenomena; Chemistry; Coenzymes; Feedback; Folic Acid; Formaldehyde; Glycine; Hydrogen; Kinetics; Models, Chemical; Protons; Schiff Bases; Serine; Structure-Activity Relationship; Tetrahydrofolates; Threonine; Transferases; Tritium | 1973 |
Mammalian folate metabolism. Regulation of folate interconversion enzymes.
Topics: Aminohydrolases; Ammonium Sulfate; Animals; Cattle; Chemical Precipitation; Chromatography, DEAE-Cellulose; Folic Acid; Folic Acid Antagonists; Formates; Hydrogen-Ion Concentration; Kinetics; Ligases; Liver; Oxidoreductases; Serine; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Transferases | 1973 |
Folated deficiency in pernicious anemia measured by determination of decreased serine synthesis in lymphocytes.
Topics: Adolescent; Adult; Aged; Anemia, Pernicious; Blood Proteins; Carbon Isotopes; Female; Folic Acid; Folic Acid Deficiency; Formates; Humans; Lymphocytes; Male; Methionine; Methods; Middle Aged; RNA; Serine; Vitamin B 12; Vitamin B 12 Deficiency | 1973 |
Effect of excess dietary L-, DL- and D-serine on the chicks.
Topics: Animals; Chickens; Diet; Female; Folic Acid; Glutamates; Growth Disorders; Male; Poultry Diseases; Pyridoxine; Serine; Vitamin B 12 | 1973 |
Effect of dietary folic acid deficiency on serine-glycine interconversion and the activity of liver serine hydroxymethyl transferase in the chick.
Topics: Animal Feed; Animals; Body Weight; Chickens; Diet; Folic Acid; Folic Acid Deficiency; Glycine; In Vitro Techniques; Liver; Male; Poultry Diseases; Serine; Tetrahydrofolates; Transferases | 1973 |
A clinical evaluation of a rapid method for determination of folate deficiency by 14C-formate incorporation into serine of lymphocytes.
Topics: Adolescent; Adult; Aged; Carbon Radioisotopes; Erythrocytes; Evaluation Studies as Topic; Female; FIGLU Test; Folic Acid; Formates; Humans; In Vitro Techniques; Lymphocytes; Male; Methods; Middle Aged; Serine | 1973 |
Diurnal variations of liver folate metabolism in rats maintained under controlled feeding schedules.
Topics: Animals; Circadian Rhythm; Eating; Folic Acid; Ligases; Liver; Male; Oxidoreductases; Rats; Serine; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Time Factors; Transferases | 1974 |
Nutritional biotin and purine requirements, and the folate metabolism of Neoaplectana glaseri.
Topics: Animals; Azaserine; Biotin; Culture Media; Depression, Chemical; Folic Acid; Nematoda; Peptide Synthases; Purines; Pyrimidines; Reproduction; Serine; Tetrahydrofolates; Transferases | 1974 |
Vitamin B 12 and methionine synthesis in Escherichia coli.
Topics: Acyltransferases; Aerobiosis; Alcohol Oxidoreductases; Anilides; Carbon Isotopes; Chromatography, Ion Exchange; Enzyme Repression; Escherichia coli; Flavin-Adenine Dinucleotide; Folic Acid; Genetics, Microbial; Homocysteine; Homoserine; Kinetics; Methionine; Methyltransferases; Mutation; Serine; Succinates; Transferases; Vitamin B 12 | 1971 |
Tetrahydrofolate-dependent enzyme activities of the rat liver in riboflavin deficiency.
Topics: Animals; Centrifugation; Chromatography, Thin Layer; Enterococcus faecalis; FIGLU Test; Folic Acid; Formates; Histidine; Hydrogen-Ion Concentration; Injections, Intramuscular; Injections, Intraperitoneal; Injections, Intravenous; Lactobacillus; Liver; Male; Methionine; Pediococcus; Potassium; Rats; Riboflavin; Riboflavin Deficiency; Serine; Tetrahydrofolate Dehydrogenase; Transferases | 1968 |
The amino-terminal residues of Bacillus subtilis proteins made in vitro.
Topics: Alanine; Bacillus subtilis; Bacterial Proteins; Carbon Isotopes; Cell-Free System; Chromatography, Gel; Folic Acid; Formates; Kinetics; Methionine; Molecular Weight; Peptide Biosynthesis; Peptide Hydrolases; RNA, Messenger; Serine; Threonine; Tritium; Valine | 1970 |
Evidence against the folate-mediated formylation of formyl-accepting methionyl transfer ribonucleic acid in Streptococcus faecalis R.
Topics: Adenine; Aminopterin; Bacterial Proteins; Culture Media; Enterococcus faecalis; Folic Acid; Folic Acid Antagonists; Formates; Guanine; Methionine; Pyrimidines; RNA, Transfer; Serine; Thymine | 1970 |
Function and control of liver alkaline phosphatase.
Topics: Alkaline Phosphatase; Animals; Bile; Cell Membrane; Cell Nucleus; Choline; DNA Replication; Drug Synergism; Fatty Acids; Female; Folic Acid; Glycine; Heparin; Hepatectomy; Hydrocortisone; Liver; Liver Regeneration; Microsomes, Liver; Mitochondria, Liver; Phosphatidylcholines; Rats; Serine; Solubility | 1972 |
Selection and characterization of mutant strains of Streptococcus faecium var. durans resistant to methasquin and amethopterin.
Topics: Culture Media; Depression, Chemical; Drug Antagonism; Drug Resistance, Microbial; Drug Synergism; Folic Acid; Folic Acid Antagonists; Genetics, Microbial; Methotrexate; Mutation; Purines; Quinazolines; Serine; Streptococcus; Tetrahydrofolates; Thymine Nucleotides | 1972 |
The aminoaciduria of pregnancy.
Topics: Alanine; Amino Acids; Female; Folic Acid; Glycine; Histidine; Humans; Kidney; Pregnancy; Renal Aminoacidurias; Serine; Statistics as Topic; Threonine | 1972 |
The oxidation of the beta carbon of serine in human folate and vitamin B 12 deficiency.
Topics: Anemia, Macrocytic; Carbon; Carbon Dioxide; Carbon Isotopes; Diet; Erythrocyte Count; Folic Acid; Folic Acid Deficiency; Hemoglobins; Histidine; Humans; Injections, Intravenous; Malonates; Oxidation-Reduction; Reticulocytes; Serine; Vitamin B 12; Vitamin B 12 Deficiency | 1972 |
The isolation of serine transhydroxymethylase from bovine brain.
Topics: Ammonium Sulfate; Animals; Brain; Carbon Isotopes; Cattle; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Enzyme Activation; Folic Acid; Hydrogen-Ion Concentration; Kinetics; Pyridoxal Phosphate; Serine; Transferases | 1972 |
Effects of testosterone on the metabolism of folate coenzymes in the rat.
Topics: Animals; Castration; Coenzymes; Depression, Chemical; Folic Acid; Formates; Ligases; Liver; Male; Oxidoreductases; Prostate; Rats; Seminal Vesicles; Serine; Stimulation, Chemical; Testosterone; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Transferases | 1972 |
Inhibition of mycobactin formation in Mycobacterium smegmatis by p-aminosalicylate. A new proposal for the mode of action of p-aminosalicylate.
Topics: Aminosalicylic Acids; Folic Acid; Growth Substances; Humans; Iron; Mycobacterium; Salicylates; Serine | 1972 |
Folate deficiency in malnutrition, malabsorption, and during phenytoin treatment diagnosed by determination of serine synthesis in lymphocytes.
Topics: Adult; Aged; Anemia; Carbon Isotopes; Epilepsy; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Humans; Lymphocytes; Malabsorption Syndromes; Male; Methionine; Middle Aged; Nutrition Disorders; Phenytoin; Proteins; RNA; Serine; Time Factors | 1972 |
Inhibition of growth of leukemia cells by enzymic folate depletion.
Topics: Animals; Carboxypeptidases; Carcinoma 256, Walker; Cell Line; Culture Media; Depression, Chemical; Folic Acid; Humans; Hypoxanthines; In Vitro Techniques; Leucovorin; Leukemia L1210; Leukemia, Experimental; Methotrexate; Pseudomonas; Serine; Thymidine | 1971 |
Effects of thyroxine on the synthesis of folate coenzymes in rat liver.
Topics: Animals; Coenzymes; Folic Acid; Formates; Ligases; Liver; Rats; Serine; Thyroidectomy; Thyroxine; Transferases | 1970 |
The mechanism of action of serine transhydroxymethylase.
Topics: Folic Acid; Formaldehyde; Glycine; Models, Chemical; Pyridoxal Phosphate; Serine; Transferases; Tritium | 1970 |
Folate metabolism in the x-irradiated rat.
Topics: Acid Phosphatase; Animals; Bone Marrow; Carbon Isotopes; Carboxypeptidases; Chromatography, DEAE-Cellulose; DNA; Female; Folic Acid; Glutamates; Hydrogen-Ion Concentration; Liver; Radiation Effects; Rats; RNA; Serine; Spleen | 1970 |
Initiation of phi-X-174 RF-primed protein with N-formylmethionine.
Topics: Alanine; Carbon Isotopes; Cell-Free System; Coliphages; Detergents; DNA, Viral; Electrophoresis; Folic Acid; Formates; Gels; Genetic Code; Kinetics; Methionine; Peptide Hydrolases; RNA, Viral; Serine; Sulfuric Acids; Tritium; Viral Proteins | 1970 |
Dietary regulation of glycolytic enzymes. X. The effect of oral, intramuscular and conjugated sex steroids on jejunal folate-metabolizing enzyme activities in normal and castrated male and female rats.
Topics: Administration, Oral; Animals; Castration; Estradiol; Female; Folic Acid; Glucuronates; Glutamates; Injections, Intramuscular; Jejunum; Ligases; Male; Metabolism; Ovary; Oxidoreductases; Progesterone; Rats; Serine; Stimulation, Chemical; Testosterone; Transferases | 1970 |
Methylation of homocysteine in Coprinus lagopus.
Topics: Basidiomycota; Folic Acid; Homocysteine; Methionine; Methylation; Serine; Transferases | 1970 |
Dietary regulation of glycolytic enzymes. VII. Effect of diet and oral folate upon folate-metabolizing enzymes in rat jejunum.
Topics: Administration, Oral; Animals; Caseins; Diet; Dietary Carbohydrates; Dietary Proteins; Fasting; Folic Acid; Fructose; Glucose; Glutamates; Intestinal Mucosa; Jejunum; Ligases; Male; Metabolism; Oxidoreductases; Rats; Serine; Transferases | 1970 |
[Stereochemistry of the incorporation of formate-3H into L-serine by rat liver].
Topics: Animals; Benzoates; Chemical Phenomena; Chemistry; Ethanol; Folic Acid; Formates; In Vitro Techniques; Ligases; Liver; Rats; Serine; Stereoisomerism; Transferases; Tritium | 1970 |
Serine transhydroxymethylase. Affinity of the active site for substrates, substrate analogues, and anions.
Topics: Alanine; Aldehydes; Aminoisobutyric Acids; Animals; Benzoates; Binding Sites; Chlorides; Cysteamine; Cysteine; Electrophoresis; Folic Acid; Glycine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Models, Biological; Organophosphonates; Phosphates; Potassium; Propionates; Pyridoxal Phosphate; Rabbits; Serine; Spectrophotometry; Stereoisomerism; Sulfates; Sulfhydryl Compounds; Sulfonic Acids; Thermodynamics; Threonine; Transferases; Ultracentrifugation | 1971 |
Tetrahydrofolate-dependent enzymes in sarcoma 180 cells sensitive and resistant to amethopterin.
Topics: Aminohydrolases; Animals; Culture Techniques; Folic Acid; Formates; Ligases; Methotrexate; Mice; Oxidoreductases; Sarcoma 180; Serine; Transferases; Ultracentrifugation | 1968 |
Serine transhydroxymethylase in developing mouse brain.
Topics: Age Factors; Animals; Animals, Newborn; Brain; Carbon Isotopes; Folic Acid; Formaldehyde; Glycine; Mice; Pyridoxal Phosphate; Serine; Tissue Extracts; Transferases | 1968 |
Physiological significance of glycine cleavage system in human liver as revealed by the study of a case of hyperglycinemia.
Topics: Adult; Carbon Dioxide; Carbon Isotopes; Female; Folic Acid; Glycine; Humans; Infant; L-Serine Dehydratase; Liver; Metabolism, Inborn Errors; Serine; Transferases | 1969 |
Purification and properties of serine hydroxymethylase from soluble and mitochondrial fractions of rabbit liver.
Topics: Animals; Antigen-Antibody Reactions; Antigens; Calcium Phosphates; Crystallography; Folic Acid; Guinea Pigs; Hot Temperature; Hydrogen-Ion Concentration; Immune Sera; Isoenzymes; Kinetics; Liver; Mitochondria, Liver; Molecular Weight; Rabbits; Serine; Spectrophotometry; Transferases; Ultracentrifugation | 1969 |
[14CO2 biosynthesis from [3-14C]serine in red blood cells].
Topics: Alanine; Aldehydes; Animals; Autoradiography; Azoles; Carbon Dioxide; Carbon Isotopes; Catalase; Chromatography; Coenzyme A; Erythrocytes; Folic Acid; Formates; Ketoglutaric Acids; Lactates; Porphyrins; Rabbits; Reticulocytes; Serine; Succinates | 1969 |
Formation of methane from serine by cell-free extracts of Methanobacillus omelianskii.
Topics: Bacteria; Carbon Dioxide; Folic Acid; In Vitro Techniques; Methane; Serine; Tetrahydrofolate Dehydrogenase; Transferases | 1965 |
The interconversion of glycine and serine by plant tissue extracts.
Topics: Carbon Isotopes; Chromatography, Paper; Folic Acid; Formaldehyde; Glycine; In Vitro Techniques; Plant Extracts; Plants; Serine | 1966 |
Serine transhydroxymethylase. Affinity of tetrahydrofolate compounds for the enzyme and enzyme-glycine complex.
Topics: Chemical Phenomena; Chemistry; Folic Acid; Glycine; Kinetics; Serine; Spectrophotometry; Transferases | 1967 |
The stereochemistry of the incorporation of formate-3H into L-serine in rat liver.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Ethanol; Folic Acid; Formates; Liver; Rats; Serine; Tritium | 1967 |
Glycine synthesis by extracts of acetone powder of rat-liver mitochondria.
Topics: Acetone; Animals; Carbon Isotopes; Dialysis; Folic Acid; Glycine; Liver; Mitochondria; Pyridoxal Phosphate; Rats; Serine; Transferases | 1967 |
Alterations in properties of mung bean (Vigna radiata) serine hydroxymethyltransferase consequent on conformation changes induced by folic acid & L-serine.
Topics: Fabaceae; Folic Acid; Glycine Hydroxymethyltransferase; Plants, Medicinal; Protein Conformation; Serine; Transferases | 1983 |
[Evaluation of biochemical criteria for sensitivity of tumor cells to methotrexate by means of mathematic simulation].
Topics: Animals; Carcinoma, Ehrlich Tumor; Folic Acid; Kinetics; Leukemia L1210; Mathematics; Methionine; Methotrexate; Models, Biological; Purines; Serine; Tetrahydrofolate Dehydrogenase; Thymidine Monophosphate | 1980 |
[Mathematical description and study of the folic acid cycle reactions].
Topics: Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Folic Acid; Humans; Kinetics; Leukemia L1210; Mathematics; Methionine; Methotrexate; Mice; Purines; Rats; Serine; Tetrahydrofolate Dehydrogenase; Thymidine Monophosphate | 1980 |
Inhibition of serine metabolism by tetrahydrohomofolate in L1210 mouse leukemia cells.
Topics: Animals; Cell Division; Cells, Cultured; Folic Acid; Glycine Hydroxymethyltransferase; Leukemia L1210; Methionine; Mice; Serine | 1981 |
Sources of one-carbon units in the folate pathway of Escherichia coli.
Topics: Amino Acids; Carbon Radioisotopes; Escherichia coli; Folic Acid; Formates; Glycine; Serine | 1982 |
Involvement of folic acid and methionine in the synthesis of certain membrane-associated nucleotide sugars by Enterococcus hirae.
Topics: Cell Fractionation; Cell Membrane; Cell-Free System; Enterococcus; Folic Acid; Methionine; Monosaccharides; S-Adenosylmethionine; Serine; Uridine Diphosphate Glucose; Uridine Diphosphate Sugars | 1994 |
Characterization of the folate-dependent mitochondrial oxidation of carbon 3 of serine.
Topics: Adenosine Diphosphate; Animals; Carbon Dioxide; Folic Acid; Formates; Formyltetrahydrofolates; Male; Mitochondria, Liver; NADP; Oligomycins; Oxidation-Reduction; Propionates; Rats; Rats, Sprague-Dawley; Serine | 1993 |
Carbon flow through the hepatic folate-dependent one-carbon pool is not altered in vitamin A-deficient rats.
Topics: Animals; Carbon; Carbon Radioisotopes; Diterpenes; Folic Acid; Liver; Male; Methionine; Random Allocation; Rats; Rats, Sprague-Dawley; Retinyl Esters; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Tritium; Vitamin A; Vitamin A Deficiency | 1996 |
Use of 13C nuclear magnetic resonance to evaluate metabolic flux through folate one-carbon pools in Saccharomyces cerevisiae.
Topics: Carbon Isotopes; Choline; Folic Acid; Formates; Glycine; Leucovorin; Magnetic Resonance Spectroscopy; Purines; Saccharomyces cerevisiae; Serine | 1997 |
Role of mitochondrial and cytoplasmic serine hydroxymethyltransferase isozymes in de novo purine synthesis in Saccharomyces cerevisiae.
Topics: Carbon Isotopes; Cell Compartmentation; Cytoplasm; Folic Acid; Formates; Glycine; Glycine Hydroxymethyltransferase; Isoenzymes; Mitochondria; Nuclear Magnetic Resonance, Biomolecular; Purines; Saccharomyces cerevisiae; Serine | 1997 |
Inhibition of dihydrofolate reductases from Toxoplasma gondii, Pneumocystis carinii, and rat liver by rotationally restricted analogues of pyrimethamine and metoprine.
Topics: Animals; Binding Sites; Computer Simulation; Folic Acid; Folic Acid Antagonists; Liver; Molecular Structure; Oxidoreductases; Pneumocystis; Pyrimethamine; Rats; Serine; Threonine; Toxoplasma | 1999 |
Defining the steps of the folate one-carbon shuffle and homocysteine metabolism.
Topics: Folic Acid; Glycine; Homocysteine; Humans; Methionine; Methylation; Serine | 2000 |
Primed, constant infusion with [2H3]serine allows in vivo kinetic measurement of serine turnover, homocysteine remethylation, and transsulfuration processes in human one-carbon metabolism.
Topics: Adult; Amino Acids; Cytosol; Folic Acid; Homocysteine; Humans; Infusions, Intravenous; Kinetics; Male; Methionine; Methylation; Mitochondria; Nutritional Status; Pilot Projects; Serine | 2000 |
Neurotransmitters in 3-phosphoglycerate dehydrogenase deficiency.
Topics: Carbohydrate Dehydrogenases; Child, Preschool; Folic Acid; Humans; Male; Neurotransmitter Agents; Phosphoglycerate Dehydrogenase; Serine | 2000 |
Ontogeny of hepatic enzymes involved in serine- and folate-dependent one-carbon metabolism in rabbits.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aging; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Brain; Carrier Proteins; Embryonic and Fetal Development; Female; Folic Acid; Glycine Hydroxymethyltransferase; Kidney; Leucovorin; Liver; Methylenetetrahydrofolate Reductase (NADPH2); Multienzyme Complexes; Oxidoreductases Acting on CH-NH Group Donors; Placenta; Pregnancy; Rabbits; Serine; Tetrahydrofolates; Transferases | 2001 |
Nitric oxide inhibits methionine synthase activity in vivo and disrupts carbon flow through the folate pathway.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Carbon; Cell Line; Coculture Techniques; Cricetinae; Endothelium, Vascular; Folic Acid; Humans; Methionine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Purine Nucleotides; Rats; Serine; Vitamin B 12 | 2001 |
Folate cofactors regulate serine metabolism in fetal ovine hepatocytes.
Topics: Animals; Bromodeoxyuridine; Folic Acid; Glycine; Hepatocytes; Serine; Sheep | 2002 |
CblE type of homocystinuria due to methionine synthase reductase deficiency: clinical and molecular studies and prenatal diagnosis in two families.
Topics: Adult; Anemia, Megaloblastic; Base Sequence; Cells, Cultured; Child; Chromatography, Ion Exchange; DNA; Female; Ferredoxin-NADP Reductase; Fibroblasts; Folic Acid; Homocysteine; Homocystinuria; Humans; Methionine; Molecular Sequence Data; Mutation; Prenatal Diagnosis; Reverse Transcriptase Polymerase Chain Reaction; Serine; Vitamin B 12 | 2002 |
Folic acid as coenzyme for the interconversion of serine and glycine.
Topics: Coenzymes; Fabaceae; Folic Acid; Glycine; Humans; Serine | 1953 |
The folic acid and serine nutrition of Leuconostoc mesenteroides P60 (Streptococcus equinus P60).
Topics: Folic Acid; Leuconostoc; Nutritional Status; Serine; Streptococcus; Streptococcus bovis | 1954 |
The interconversion of serine and glycine: role of pteroylglutamic acid and other cofactors.
Topics: Fabaceae; Folic Acid; Glycine; Humans; Serine | 1954 |
The synthesis of serine and Leuconostoc citrovorum factor by cell suspensions of Streptococcus faecalis R.
Topics: Antimetabolites; Enterococcus faecalis; Folic Acid; Leuconostoc; Leucovorin; Serine; Streptococcus; Suspensions | 1954 |
The incorporation of serine-3-C14 into citrovorum factor.
Topics: Antimetabolites; Folic Acid; Leucovorin; Serine | 1956 |
The interconversion of serine and glycine; preparation and properties of catalytic derivatives of pteroylglutamic acid.
Topics: Catalysis; Coenzymes; Fabaceae; Folic Acid; Glycine; Humans; Liver; Serine | 1957 |
The interconversion of serine and glycine; some further properties of the enzyme system.
Topics: Coenzymes; Fabaceae; Folic Acid; Glycine; Humans; Liver; Serine | 1957 |
Incorporation of serine-3-C14 and formaldehyde-C14 into methionine in vitro. I. Role of folic acid.
Topics: Biochemical Phenomena; Folic Acid; Folic Acid Deficiency; Formaldehyde; Humans; In Vitro Techniques; Liver; Methionine; Serine | 1957 |
The role of polyglutamyl pteridine coenzymes in serine metabolism. III. The enzymatic formation of dihydrofolic acid and dihydroteropterin.
Topics: Clostridium; Coenzymes; Folic Acid; Folic Acid Antagonists; Humans; Pteridines; Serine | 1958 |
Interaction of formaldehyde and tetrahydrofolic acid and its relation to the enzymic synthesis of serine.
Topics: Biochemical Phenomena; Folic Acid; Formaldehyde; Serine; Tetrahydrofolates | 1958 |
The influence of folic acid, threonine and glycine on serine synthesis in Tetrahymena.
Topics: Amino Acids; Folic Acid; Glycine; Humans; Serine; Tetrahymena; Threonine | 1960 |
Influence of dietary glycine and serine on lipid metabolism in the rat in folic acid deficiency.
Topics: Animals; Diet; Folic Acid; Folic Acid Deficiency; Glycine; Lipid Metabolism; Lipids; Nutrition Assessment; Nutritional Status; Rats; Serine | 1960 |
FOLIC ACID METABOLISM IN ANTIFOLIC-RESISTANT MUTANTS OF STREPTOCOCCUS FAECALIS.
Topics: Adenine; Drug Resistance, Microbial; Enterococcus faecalis; Folic Acid; Guanine; Metabolism; Methotrexate; Mutation; Purines; Research; Serine; Thymine; Xanthines | 1964 |
OROTIC ACID AND METABOLISM OF ONE CARBON UNIT: CONVERSION OF FOLIC ACID TO CITROVORUM FACTOR AND METHIONINE SYNTHESIS IN CHICK LIVER.
Topics: Animals; Carbon; Chickens; Folic Acid; Homocysteine; Leuconostoc; Leucovorin; Liver; Metabolism; Methionine; Orotic Acid; Poultry; Proteins; Research; Serine; Vitamin B 12; Vitamin B 12 Deficiency | 1963 |
ORGAN AND INTRACELLULAR LOCATION OF THE METHIONINE METHYL GROUP SYNTHESIZING SYSTEM OF THE RAT.
Topics: Adenosine Triphosphate; Brain; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; Glucose; Homocysteine; Kidney; Leuconostoc; Liver; Magnesium; Methionine; Muscles; NAD; Pectoralis Muscles; Proteins; Pyridoxal Phosphate; Rats; Research; Serine; Spectrophotometry | 1964 |
QUANTITATIVE COLONIAL GROWTH OF MAMMALIAN CELLS IN FIBRIN CELLS.
Topics: Asparagine; Fibrin; Folic Acid; Immune Sera; Mast Cells; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Serine; Thrombin; Tissue Culture Techniques | 1964 |
THE FATE OF CARBON-19 IN THE COURSE OF OESTROGEN BIOSYNTHESIS FROM TESTOSTERONE-19-14C.
Topics: Carbon; Carbon Dioxide; Carbon Isotopes; Cyanides; Estradiol Congeners; Estrogens; Folic Acid; Formaldehyde; Formates; Lipogenesis; Magnesium; Metabolism; Methionine; Serine; Testosterone | 1965 |
Biosynthesis of glycine and serine in normal and folic acid-deficient rats.
Topics: Animals; Fabaceae; Folic Acid; Folic Acid Deficiency; Glycine; Rats; Serine | 1955 |
A study of the mechanism of serine biosynthesis.
Topics: Antimetabolites; Folic Acid; Formaldehyde; Glycine; Liver Extracts; Serine | 1955 |
Stimulatory effects of glycine, L-serine, folic acid and related compounds on growth of cell cultures.
Topics: Cell Culture Techniques; Fabaceae; Folic Acid; Glycine; Physiological Phenomena; Serine; Tissue Culture Techniques | 1960 |
Synthesis of serine by Coxiella burnetii.
Topics: Coxiella; Coxiella burnetii; Folic Acid; Serine | 1961 |
Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donor.
Topics: Adult; Carbon; Carbon Isotopes; Female; Folic Acid; Homocysteine; Humans; Leucine; Methionine; Methylation; Reference Values; Serine | 2004 |
Leuconostoc citrovorum factor and the synthesis of serine by micro-organisms.
Topics: Antimetabolites; Bacteria; Folic Acid; Leuconostoc; Leucovorin; Serine | 1951 |
The relation of folic acid to the metabolism of serine.
Topics: Folic Acid; Humans; Nitrogen; Nitrogen Radioisotopes; Serine | 1950 |
Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women.
Topics: Adult; Amino Acids; Female; Folic Acid; Folic Acid Deficiency; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Leucine; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Serine | 2005 |
Influence of DNA repair gene polymorphisms of hOGG1, XRCC1, XRCC3, ERCC2 and the folate metabolism gene MTHFR on chromosomal aberration frequencies.
Topics: Adult; Chromosome Aberrations; Cohort Studies; Cysteine; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; Folic Acid; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Serine; X-ray Repair Cross Complementing Protein 1; Xeroderma Pigmentosum Group D Protein | 2006 |
Reduced folate supply as a key to enhanced L-serine production by Corynebacterium glutamicum.
Topics: Bacterial Proteins; Biotechnology; Corynebacterium glutamicum; Culture Media; Folic Acid; Gene Expression Regulation, Bacterial; Genetic Engineering; Glycine Hydroxymethyltransferase; Mutation; Serine; Tetrahydrofolates | 2007 |
In silico experimentation with a model of hepatic mitochondrial folate metabolism.
Topics: Animals; Cytosol; Dose-Response Relationship, Drug; Folic Acid; Glycine; Glycine Hydroxymethyltransferase; Humans; Methionine; Mitochondria, Liver; Models, Biological; Osmolar Concentration; Proteins; Serine; Tetrahydrofolates | 2006 |
Nonconserved residues Ala287 and Ser290 of the Cryptosporidium hominis thymidylate synthase domain facilitate its rapid rate of catalysis.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Cryptosporidium; Crystallography, X-Ray; Folic Acid; Kinetics; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Protozoan Proteins; Quinazolines; Serine; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Thymidine Monophosphate; Thymidylate Synthase | 2007 |
A genome-wide and metabolic analysis determined the adaptive response of Arabidopsis cells to folate depletion induced by methotrexate.
Topics: Adaptation, Biological; Arabidopsis; Carbon; Cell Division; Energy Metabolism; Folic Acid; Gene Expression; Gene Expression Profiling; Genome, Plant; Homeostasis; Leucovorin; Methotrexate; Nucleotides; Plastids; Serine; Sulfates; Xenobiotics | 2008 |
Susceptibility to intestinal tumorigenesis in folate-deficient mice may be influenced by variation in one-carbon metabolism and DNA repair.
Topics: Aminohydrolases; Animals; Colorectal Neoplasms; Diet; DNA Methylation; DNA Polymerase beta; DNA Repair; Folic Acid; Folic Acid Deficiency; Formate-Tetrahydrofolate Ligase; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Multienzyme Complexes; RNA, Messenger; Serine; Tetrahydrofolates; Uracil-DNA Glycosidase | 2011 |
[Metabolic flux analysis of L-serine synthesis by Corynebacterium glutamicum SYPS-062].
Topics: Citric Acid Cycle; Corynebacterium glutamicum; Fermentation; Folic Acid; Serine; Vitamin B 12 | 2010 |
Short- and long-term dynamic responses of the metabolic network and gene expression in yeast to a transient change in the nutrient environment.
Topics: Carbon; Catabolite Repression; Energy Metabolism; Folic Acid; Gene Expression Profiling; Gene Expression Regulation, Fungal; Glucose; Glycine; Inosine; Metabolic Networks and Pathways; Nitrogen; Nucleotides; Quaternary Ammonium Compounds; Saccharomyces cerevisiae; Serine; Systems Biology; Transcriptome | 2012 |
Effect of dietary supplementation with folate on choline deficiency-induced hyperhomocysteinemia in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine-Homocysteine S-Methyltransferase; Choline Deficiency; Cystathionine beta-Synthase; Dietary Supplements; Folic Acid; Hyperhomocysteinemia; Liver; Male; Random Allocation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; RNA, Messenger; Serine; Tetrahydrofolates | 2012 |
The tRNA recognition mechanism of folate/FAD-dependent tRNA methyltransferase (TrmFO).
Topics: Anticodon; Bacterial Proteins; Base Sequence; Electrophoretic Mobility Shift Assay; Enzyme Assays; Flavin-Adenine Dinucleotide; Folic Acid; Gene Expression Regulation, Bacterial; Glycine; Glycine Hydroxymethyltransferase; Kinetics; Models, Biological; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; RNA, Messenger; RNA, Transfer; RNA, Transfer, Phe; Serine; Substrate Specificity; Thermus thermophilus; tRNA Methyltransferases; Uridine | 2012 |
Overexpression of the mitochondrial folate and glycine-serine pathway: a new determinant of methotrexate selectivity in tumors.
Topics: Biological Transport; Folic Acid; Folic Acid Antagonists; Glycine; Humans; Methotrexate; Mitochondria; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Serine; Transcriptome | 2013 |
North-south gradients in plasma concentrations of B-vitamins and other components of one-carbon metabolism in Western Europe: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study.
Topics: Adult; Aged; Alcohol Drinking; Chronic Disease; Ethnicity; Europe; Female; Folic Acid; Glycine; Health Behavior; Humans; Life Style; Male; Middle Aged; Prospective Studies; Sarcosine; Serine; Sex Factors; Smoking; Vitamin B 12 | 2013 |
Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells.
Topics: Adenosine Triphosphate; Amino Acid Oxidoreductases; Animals; Carrier Proteins; Cell Line, Tumor; Embryonic Stem Cells; Energy Metabolism; Fatty Acids; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Glycine; Humans; Male; Metabolic Flux Analysis; Metabolic Networks and Pathways; Methotrexate; Mice; Multienzyme Complexes; NADP; Neoplasms; Protein Biosynthesis; Purines; Serine; Transferases | 2013 |
Quantitative flux analysis reveals folate-dependent NADPH production.
Topics: Animals; Carbon; Cell Line; Cell Line, Tumor; Cytosol; Folic Acid; Glutathione; Glycine; HEK293 Cells; Humans; Isoenzymes; Leucovorin; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mitochondria; NADP; Oxidation-Reduction; Oxidative Stress; Pentose Phosphate Pathway; Serine; Tetrahydrofolates | 2014 |
Effect of cofactor folate on the growth of Corynebacterium glutamicum SYPS-062 and L-serine accumulation.
Topics: Cell Proliferation; Coenzymes; Corynebacterium glutamicum; Enzyme Inhibitors; Fermentation; Folic Acid; Gene Deletion; Serine; Sulfamethoxazole; Transaminases | 2014 |
In vivo kinetics of formate metabolism in folate-deficient and folate-replete rats.
Topics: Animals; Choline; Dimethylglycine Dehydrogenase; Folic Acid; Folic Acid Deficiency; Formaldehyde; Formates; Glycine; Histidine; Liver; Male; Methionine; Mitochondria; Mitochondria, Liver; Oxygen; Rats; Rats, Sprague-Dawley; Sarcosine Dehydrogenase; Serine; Tetrahydrofolates | 2015 |
Kinetic mechanism and the rate-limiting step of Plasmodium vivax serine hydroxymethyltransferase.
Topics: Folic Acid; Glycine; Glycine Hydroxymethyltransferase; Hydrogen-Ion Concentration; Kinetics; Plasmodium vivax; Protein Binding; Protozoan Proteins; Serine; Thermodynamics | 2015 |
The Phosphorylation State of GSK3β Serine 9 Correlated to the Development of Valproic Acid-Associated Fetal Cardiac Teratogenicity, Fetal VPA Syndrome, Rescued by Folic Acid Administration.
Topics: Animals; Animals, Genetically Modified; Anticonvulsants; Bradycardia; Cell Proliferation; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Female; Folic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart Defects, Congenital; Heart Ventricles; Male; Myocytes, Cardiac; Phosphorylation; Serine; Valproic Acid; Vitamins; Zebrafish | 2016 |
A Protein Extract from Chicken Reduces Plasma Homocysteine in Rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Caseins; Chickens; Choline; Cystathionine gamma-Lyase; Cysteine; Dietary Proteins; Folic Acid; Glycine; Homocysteine; Liver; Male; Meat; Methionine; Rats; Rats, Wistar; Riboflavin; RNA, Messenger; Sarcosine; Serine; Vitamin B 12; Vitamin B 6 | 2015 |
Electrocatalytic boost up of epinephrine and its simultaneous resolution in the presence of serotonin and folic acid at poly(serine)/multi-walled carbon nanotubes composite modified electrode: A voltammetric study.
Topics: Biosensing Techniques; Catalysis; Dielectric Spectroscopy; Electrochemical Techniques; Electrodes; Epinephrine; Folic Acid; Glass; Hydrogen-Ion Concentration; Limit of Detection; Nanocomposites; Nanotubes, Carbon; Serine; Serotonin | 2015 |
Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism.
Topics: Adult; Animals; Carbon; DNA Helicases; DNA Replication; DNA, Mitochondrial; Female; Folic Acid; Glucose; Glutathione; Humans; Male; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Myopathies; Mitochondrial Proteins; Models, Molecular; Mutation; Nucleotides; Serine; Spinocerebellar Degenerations | 2016 |
Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway.
Topics: Aminoimidazole Carboxamide; Carbon; Cell Compartmentation; Cell Proliferation; Colonic Neoplasms; CRISPR-Cas Systems; Cytosol; Folic Acid; Formates; Gene Knockout Techniques; Gene Library; Glycine; Glycine Hydroxymethyltransferase; HCT116 Cells; HEK293 Cells; Humans; Leucovorin; Metabolic Networks and Pathways; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondria; Mutation; NADP; Ribonucleotides; Serine; Xenograft Model Antitumor Assays | 2016 |
Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism.
Topics: Alcohol Dehydrogenase; Animals; Carbon; Cell Line; Chickens; Coenzymes; Cross-Linking Reagents; DNA Damage; DNA Repair; Folic Acid; Formaldehyde; Humans; Inactivation, Metabolic; Metabolic Networks and Pathways; Mice; Mutagens; Nucleotides; Oxidation-Reduction; Serine; Tetrahydrofolates | 2017 |
Cobalamin Deficiency Results in Increased Production of Formate Secondary to Decreased Mitochondrial Oxidation of One-Carbon Units in Rats.
Topics: Animals; Carbon; Carbon Dioxide; Cytosol; Folic Acid; Formates; Glycine; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Random Allocation; Rats, Sprague-Dawley; S-Adenosylmethionine; Sarcosine; Serine; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation.
Topics: Cell Line, Tumor; Cell Nucleus; Citric Acid Cycle; DNA Methylation; DNA, Mitochondrial; Epigenesis, Genetic; Folic Acid; HEK293 Cells; Humans; Methionine; Mitochondria; NAD; Osteoblasts; Oxidation-Reduction; Serine; Tricarboxylic Acids | 2018 |
Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation.
Topics: Aminohydrolases; B-Lymphocytes; Cell Transformation, Viral; Epstein-Barr Virus Infections; Epstein-Barr Virus Nuclear Antigens; Female; Folic Acid; Glycolysis; HEK293 Cells; Herpesvirus 4, Human; Humans; Lymphocyte Activation; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondria; Multifunctional Enzymes; NADP; Oxidation-Reduction; Proteome; Proto-Oncogene Proteins c-myc; Serine | 2019 |
Dietary serine-microbiota interaction enhances chemotherapeutic toxicity without altering drug conversion.
Topics: Animals; Caenorhabditis elegans; Dietary Supplements; Escherichia coli; Floxuridine; Folic Acid; Food-Drug Interactions; Gastrointestinal Microbiome; Serine; Thymidine; Uracil Nucleotides | 2020 |
In Silico Prediction of Metabolic Fluxes in Cancer Cells with Altered S-adenosylmethionine Decarboxylase Activity.
Topics: Adenosine Triphosphate; Adenosylmethionine Decarboxylase; Antineoplastic Agents; Computer Simulation; Epigenesis, Genetic; Folic Acid; Glutathione; Humans; Methionine; Models, Biological; Neoplasms; Phenotype; Polyamines; Serine; Taurine; Uric Acid | 2021 |
The toxic side of one-carbon metabolism and epigenetics.
Topics: Animals; Carbon; Epigenesis, Genetic; Folic Acid; Humans; Lysine; Serine | 2021 |
SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication.
Topics: A549 Cells; Animals; Carbon; Chlorocebus aethiops; COVID-19; Cytopathogenic Effect, Viral; Folic Acid; Folic Acid Antagonists; Glucose; Humans; Methotrexate; RNA, Viral; SARS-CoV-2; Serine; Transcription, Genetic; Vero Cells; Viral Proteins; Virus Replication | 2021 |
Functional role of serine 318 of the proton-coupled folate transporter in methotrexate transport.
Topics: Folic Acid; HeLa Cells; Humans; Methotrexate; Proton-Coupled Folate Transporter; Serine | 2021 |
Serine catabolism generates liver NADPH and supports hepatic lipogenesis.
Topics: Acetyl Coenzyme A; Adipose Tissue; Aminohydrolases; Animals; Fatty Acids; Female; Folic Acid; Formate-Tetrahydrofolate Ligase; Glutamine; Glycine Hydroxymethyltransferase; Hepatocytes; Lipid Metabolism; Lipogenesis; Liver; Male; Metabolic Networks and Pathways; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Multienzyme Complexes; NADP; Oxidative Phosphorylation; Oxidoreductases Acting on CH-NH Group Donors; Serine | 2021 |