serine and fluorouracil

serine has been researched along with fluorouracil in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (36.36)	18.7374
1990's	1 (9.09)	18.2507
2000's	1 (9.09)	29.6817
2010's	2 (18.18)	24.3611
2020's	3 (27.27)	2.80

Authors

Authors	Studies
Jones, GH; Weissbach, H	1
Wolberg, WH	1
Ishizuka, M; Kawatsu, M; Takeuchi, T; Yamashita, T	1
SOFFER, RL	1
MORSE, PA; POTTER, VR	1
Iggo, RD; Kaeser, MD; Pebernard, S	1
Balmer, MT; Gal, S; Goodwine, JS; Katz, RD; Liao, S	1
Asai, A; Doki, Y; Ishii, H; Kawamoto, K; Konno, M; Mori, M; Nishida, N; Satoh, T	1
Chong, SJF; Collins, M; Davids, M; Herbaux, C; Iskandar, K; Lai, JXH; Loh, T; Low, ICC; Pervaiz, S; Qu, J; Raman, D; Valentin, R	1
Buyukozkan, M; Chen, J; Chen, Q; Dannenberg, AJ; Dow, LE; Elemento, O; Foronda, M; Galluzzi, L; Gross, SS; Ha, T; Krumsiek, J; McNally, EM; Montrose, DC; Saha, S; Verma, A; Yantiss, RK; Zhou, XK	1
Arcangeli, A; Caselli, A; Chiarugi, P; Cirri, P; Colantuoni, V; Leo, A; Lottini, T; Maddocks, ODK; Muccillo, L; Nesi, I; Paoli, P; Pardella, E; Parri, M; Pranzini, E; Raugei, G; Sabatino, L; Santi, A; Taddei, ML; Uribe, AH; Zhang, T	1

Reviews

1 review(s) available for serine and fluorouracil

Article	Year
The one-carbon metabolism pathway highlights therapeutic targets for gastrointestinal cancer (Review). International journal of oncology, 2017, Volume: 50, Issue:4 Topics: Aminohydrolases; Antineoplastic Agents; Fluorouracil; Folic Acid; Folic Acid Antagonists; Gastrointestinal Neoplasms; Glycine Hydroxymethyltransferase; Humans; Metabolic Networks and Pathways; Metabolome; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); MicroRNAs; Mitochondria; Molecular Targeted Therapy; Multienzyme Complexes; Nucleosides; Nucleotides; Oxidoreductases Acting on CH-NH Group Donors; Purines; Reactive Oxygen Species; Serine	2017

Article

Year

The one-carbon metabolism pathway highlights therapeutic targets for gastrointestinal cancer (Review).

International journal of oncology, 2017, Volume: 50, Issue:4

Topics: Aminohydrolases; Antineoplastic Agents; Fluorouracil; Folic Acid; Folic Acid Antagonists; Gastrointestinal Neoplasms; Glycine Hydroxymethyltransferase; Humans; Metabolic Networks and Pathways; Metabolome; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); MicroRNAs; Mitochondria; Molecular Targeted Therapy; Multienzyme Complexes; Nucleosides; Nucleotides; Oxidoreductases Acting on CH-NH Group Donors; Purines; Reactive Oxygen Species; Serine

2017

Other Studies

10 other study(ies) available for serine and fluorouracil

Article	Year
RNA metabolism in Streptomyces antibioticus; effect of 5-fluorouracil on the appearance of phenoxazinone synthetase. Archives of biochemistry and biophysics, 1970, Volume: 137, Issue:2 Topics: Amino Acids; Carbon Isotopes; Centrifugation, Density Gradient; Chloramphenicol; Chromatography; Dactinomycin; Fluorouracil; ortho-Aminobenzoates; Oxazines; Oxidoreductases; Proline; RNA, Bacterial; RNA, Transfer; Serine; Streptomyces; Time Factors; Tritium; Uridine	1970
Response of DNA thymine synthesis in human tumor and normal tissue to 5-fluorouracil. Cancer research, 1972, Volume: 32, Issue:1 Topics: Breast Neoplasms; Carbon Isotopes; Chromatography, Paper; Colon; Colonic Neoplasms; Depression, Chemical; DNA; DNA, Neoplasm; Female; Fluorouracil; Formates; Humans; In Vitro Techniques; Lung Neoplasms; Methyltransferases; Ovarian Neoplasms; Serine; Thymidine; Thymine; Thymine Nucleotides; Tritium; Uracil Nucleotides	1972
Effect of conagenin on thrombocytopenia induced by antitumor agents in mice. The Journal of antibiotics, 1994, Volume: 47, Issue:10 Topics: Animals; Antineoplastic Agents; Bone Marrow; Cells, Cultured; Fluorouracil; Interleukin-2; Interleukin-3; Interleukin-6; Leukocyte Count; Mice; Mice, Inbred C57BL; Mitomycin; Platelet Count; Serine; Spleen; Thrombocytopenia	1994
STUDIES ON THE BIOLOGICAL ACTIVITY OF RIBONUCLEIC ACID ISOLATED FROM ESCHERICHIA COLI AFTER EXPOSURE TO 5-FLUOROURACIL. Biochimica et biophysica acta, 1964, Jul-22, Volume: 87 Topics: Arginine; Escherichia coli; Fluorouracil; Leucine; Metabolism; Pharmacology; Proline; Proteins; Research; RNA; RNA, Bacterial; Serine; Spectrophotometry	1964
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. I. SUSPENSION CELL CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA. Cancer research, 1965, Volume: 25 Topics: Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Floxuridine; Fluorouracil; Glycine; Liver Neoplasms; Liver Neoplasms, Experimental; Metabolism; Methotrexate; Mutation; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Pyrimidines; Rats; Research; Serine; Thymidine; Thymidine Kinase; Thymine; Tissue Culture Techniques; Toxicology; Uracil	1965
Regulation of p53 stability and function in HCT116 colon cancer cells. The Journal of biological chemistry, 2004, Feb-27, Volume: 279, Issue:9 Topics: Animals; Antineoplastic Agents; Apoptosis; Colonic Neoplasms; DNA Damage; Doxorubicin; Drug Stability; Fibroblasts; Flow Cytometry; Fluorouracil; Gene Expression; Genetic Vectors; Humans; Immunoblotting; Lentivirus; Lung; Mice; Mutagenesis; Nuclear Proteins; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Reverse Transcriptase Polymerase Chain Reaction; Serine; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2004
Doxorubicin and 5-fluorouracil induced accumulation and transcriptional activity of p53 are independent of the phosphorylation at serine 15 in MCF-7 breast cancer cells. Cancer biology & therapy, 2014, Volume: 15, Issue:8 Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Checkpoint Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Doxorubicin; Female; Fluorouracil; Humans; MCF-7 Cells; Nuclear Proteins; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Serine; Transcription, Genetic; Tumor Suppressor Protein p53	2014
Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism. Nucleic acids research, 2020, 12-16, Volume: 48, Issue:22 Topics: Apoptosis; Cell Proliferation; Cisplatin; DNA Damage; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fluorouracil; Humans; Jurkat Cells; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Mitochondria; Oxidation-Reduction; Oxidative Stress; Phosphorylation; Primary Cell Culture; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Serine	2020
Exogenous and Endogenous Sources of Serine Contribute to Colon Cancer Metabolism, Growth, and Resistance to 5-Fluorouracil. Cancer research, 2021, 05-01, Volume: 81, Issue:9 Topics: Aged; Animals; Antimetabolites, Antineoplastic; Colonic Neoplasms; Diet; DNA Damage; Drug Resistance, Neoplasm; Female; Fluorouracil; Gene Expression; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Male; Mice; Mice, Nude; Mice, Transgenic; Middle Aged; Pregnancy; Serine; Transaminases; Treatment Outcome; Tumor Burden; Xenograft Model Antitumor Assays	2021
SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis. Cell reports, 2022, 08-16, Volume: 40, Issue:7 Topics: Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Neoplasm; Fluorouracil; Humans; Mitochondria; Neoplasms; Nucleotides; Serine	2022