serine and eponemycin

serine has been researched along with eponemycin in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (55.56)18.2507
2000's0 (0.00)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Hanada, M; Kaneta, K; Konishi, M; Nishiyama, Y; Oki, T; Sugawara, K; Toda, S; Tomita, K; Yamamoto, H1
Ashino, H; Hasegawa, M; Morita, I; Murota, S; Oikawa, T; Shimamura, M1
Hatori, M; Kamei, H; Konishi, M; Nishiyama, Y; Oki, T; Sugawara, K; Tomita, K1
Auth, H; Crews, CM; Meng, L; Sin, N1
Crews, CM; Kwok, BH; Meng, L; Sin, N1
Dorrestein, PC; Kaysser, L; Moore, BS; Noel, JP; Schorn, M; Zettler, J1
Liu, J; Zhang, W; Zhu, X1
Grond, S; Kaysser, L; Kulik, A; Zettler, J; Zubeil, F1
Corless, BC; David, Y; Geißen, R; Prescott, NA; Scheinberg, DA; Tan, DS1

Other Studies

9 other study(ies) available for serine and eponemycin

ArticleYear
Epoxomicin, a new antitumor agent of microbial origin.
    The Journal of antibiotics, 1992, Volume: 45, Issue:11

    Topics: Actinomycetales; Amides; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Chemical Phenomena; Chemistry, Physical; Fermentation; Magnetic Resonance Spectroscopy; Melanoma, Experimental; Molecular Structure; Oligopeptides; Serine; Spectrophotometry

1992
Eponemycin, a novel antibiotic, is a highly powerful angiogenesis inhibitor.
    Biochemical and biophysical research communications, 1991, Dec-31, Volume: 181, Issue:3

    Topics: Allantois; Amides; Animals; Antibiotics, Antineoplastic; Carotid Arteries; Cell Division; Cell Movement; Cells, Cultured; Chick Embryo; Chorion; Dose-Response Relationship, Drug; Endothelium, Vascular; Neovascularization, Pathologic; Serine

1991
Eponemycin, a new antibiotic active against B16 melanoma. I. Production, isolation, structure and biological activity.
    The Journal of antibiotics, 1990, Volume: 43, Issue:1

    Topics: Amides; Animals; Antibiotics, Antineoplastic; DNA, Neoplasm; Fermentation; Humans; Leukemia L1210; Leukemia P388; Melanoma, Experimental; Mice; Molecular Structure; RNA, Neoplasm; Serine; Streptomyces; Tumor Cells, Cultured

1990
Eponemycin analogues: syntheses and use as probes of angiogenesis.
    Bioorganic & medicinal chemistry, 1998, Volume: 6, Issue:8

    Topics: Amides; Animals; Antibiotics, Antineoplastic; Biotin; Cattle; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Humans; Ligands; Neovascularization, Physiologic; Receptors, Drug; Serine

1998
Eponemycin exerts its antitumor effect through the inhibition of proteasome function.
    Cancer research, 1999, Jun-15, Volume: 59, Issue:12

    Topics: Amides; Animals; Antibiotics, Antineoplastic; Apoptosis; Cattle; Cell Cycle; Cells, Cultured; Cysteine Endopeptidases; Mice; Multienzyme Complexes; Proteasome Endopeptidase Complex; Serine

1999
Genetic basis for the biosynthesis of the pharmaceutically important class of epoxyketone proteasome inhibitors.
    ACS chemical biology, 2014, Jan-17, Volume: 9, Issue:1

    Topics: Amides; Base Sequence; Genes, Bacterial; Humans; Models, Molecular; Molecular Sequence Data; Multigene Family; Oligopeptides; Proteasome Inhibitors; Serine; Streptomyces

2014
Identifying the Minimal Enzymes Required for Biosynthesis of Epoxyketone Proteasome Inhibitors.
    Chembiochem : a European journal of chemical biology, 2015, Volume: 16, Issue:18

    Topics: Amides; Chromatography, High Pressure Liquid; Escherichia coli; Ketones; Magnetic Resonance Spectroscopy; Mass Spectrometry; Multigene Family; Peptide Synthases; Polyketide Synthases; Proteasome Inhibitors; Serine

2015
Epoxomicin and Eponemycin Biosynthesis Involves gem-Dimethylation and an Acyl-CoA Dehydrogenase-Like Enzyme.
    Chembiochem : a European journal of chemical biology, 2016, 05-03, Volume: 17, Issue:9

    Topics: Acyl-CoA Dehydrogenase; Amides; Chromatography, High Pressure Liquid; Isotope Labeling; Magnetic Resonance Spectroscopy; Methionine; Multigene Family; Oligopeptides; Proteasome Inhibitors; Serine; Streptomyces; Tandem Mass Spectrometry

2016
Chemoenzymatic Synthesis of Novel Cytotoxic Epoxyketones Using the Eponemycin Biosynthetic Enzyme EpnF.
    ACS chemical biology, 2023, 06-16, Volume: 18, Issue:6

    Topics: Amides; Antineoplastic Agents; Proteasome Inhibitors; Serine

2023