serine has been researched along with enkephalin, ala(2)-mephe(4)-gly(5)- in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Howells, RD; Shahrestanifar, M; Wang, WW | 1 |
| George, SR; O'Dowd, BF; Pak, Y | 1 |
| Bertin, B; Capeyrou, R; Corbani, M; Emorine, LJ; Lepage, JF; Riond, J | 1 |
| Wang, HL | 1 |
| Befort, K; Decaillot, FM; Filliol, D; Gaveriaux-Ruff, C; Hoehe, MR; Kieffer, BL | 1 |
| Burd, AL; Chang, CY; El Kouhen, R; Erickson-Herbrandson, LJ; Law, PY; Loh, HH | 1 |
| Bidlack, JM; Bilsky, EJ; Davis, P; Keyari, CM; Knapp, BI; Lowery, JJ; Polt, R; Porreca, F; Yeomans, L | 1 |
| de la Torre-Madrid, E; Gaitán, G; Garzón, J; Rodríguez-Muñoz, M; Sánchez-Blázquez, P | 1 |
| Burlet-Schiltz, O; Dauvillier, S; Froment, C; Mollereau, C; Moulédous, L; Zajac, JM | 1 |
9 other study(ies) available for serine and enkephalin, ala(2)-mephe(4)-gly(5)-
| Article | Year |
|---|---|
Studies on inhibition of mu and delta opioid receptor binding by dithiothreitol and N-ethylmaleimide. His223 is critical for mu opioid receptor binding and inactivation by N-ethylmaleimide.
Topics: Amino Acid Sequence; Analgesics; Base Sequence; Binding Sites; Cell Line; Cell Membrane; Dithiothreitol; DNA Primers; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylmaleimide; Histidine; Humans; Kidney; Kinetics; Ligands; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Protein Structure, Secondary; Receptors, Opioid, delta; Receptors, Opioid, mu; Recombinant Fusion Proteins; Serine; Transfection | 1996 |
Agonist-induced desensitization of the mu opioid receptor is determined by threonine 394 preceded by acidic amino acids in the COOH-terminal tail.
Topics: Alanine; Amino Acid Sequence; Animals; Binding, Competitive; CHO Cells; Cricetinae; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Point Mutation; Rats; Receptors, Opioid, mu; Recombinant Proteins; Serine; Threonine; Transfection | 1997 |
Agonist-induced signaling and trafficking of the mu-opioid receptor: role of serine and threonine residues in the third cytoplasmic loop and C-terminal domain.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Activation; Etorphine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Morphine; Mutagenesis, Site-Directed; Receptors, Opioid, mu; Serine; Signal Transduction; Threonine | 1997 |
A cluster of Ser/Thr residues at the C-terminus of mu-opioid receptor is required for G protein-coupled receptor kinase 2-mediated desensitization.
Topics: Analgesics, Opioid; Animals; beta-Adrenergic Receptor Kinases; Cell Line; Cyclic AMP-Dependent Protein Kinases; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; G-Protein-Coupled Receptor Kinase 2; Humans; Naloxone; Narcotic Antagonists; Rats; Receptors, Opioid, mu; Serine; Threonine; Transfection | 2000 |
A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling.
Topics: Analgesics, Opioid; Animals; Asparagine; Aspartic Acid; Cells, Cultured; COS Cells; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Mutagenesis, Site-Directed; Narcotics; Polymorphism, Single Nucleotide; Proline; Receptors, Opioid, mu; Serine; Signal Transduction; Sulfur Radioisotopes | 2001 |
Phosphorylation of Ser363, Thr370, and Ser375 residues within the carboxyl tail differentially regulates mu-opioid receptor internalization.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Diprenorphine; Endocytosis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphates; Phosphorylation; Phosphoserine; Phosphothreonine; Rats; Receptors, Opioid, mu; Recombinant Proteins; Serine; Threonine; Transfection | 2001 |
Glycosylation improves the central effects of DAMGO.
Topics: Amides; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Glucose; Glycine; Glycosylation; Hydrophobic and Hydrophilic Interactions; Injections, Intraventricular; Lactose; Male; Mice; Mice, Inbred ICR; Receptors, Opioid, mu; Serine; Solubility; Water; Xylose | 2007 |
RGS14 prevents morphine from internalizing Mu-opioid receptors in periaqueductal gray neurons.
Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Endocytosis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Activation; G-Protein-Coupled Receptor Kinases; Gene Silencing; Hot Temperature; Injections, Intraventricular; Male; Mice; Molecular Sequence Data; Morphine; Neurons; Oligonucleotides, Antisense; Pain; Pain Measurement; Pain Threshold; Periaqueductal Gray; Phosphorylation; Receptors, Opioid, mu; RGS Proteins; Serine; Synaptosomes; Time Factors | 2007 |
GRK2 protein-mediated transphosphorylation contributes to loss of function of μ-opioid receptors induced by neuropeptide FF (NPFF2) receptors.
Topics: Amino Acid Sequence; Analgesics, Opioid; Arrestins; beta-Arrestins; Cell Line, Tumor; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; G-Protein-Coupled Receptor Kinase 2; Gene Knockdown Techniques; Heterotrimeric GTP-Binding Proteins; Humans; Molecular Sequence Data; Neuroblastoma; Phosphorylation; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Receptors, Opioid, mu; Second Messenger Systems; Serine; Signal Transduction | 2012 |