serine has been researched along with cycloserine in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (46.43) | 18.7374 |
| 1990's | 8 (14.29) | 18.2507 |
| 2000's | 9 (16.07) | 29.6817 |
| 2010's | 10 (17.86) | 24.3611 |
| 2020's | 3 (5.36) | 2.80 |
| Authors | Studies |
|---|---|
| Brandsch, M; Gebauer, S; Laug, L; Schäfer, S; Thondorf, I; Voigt, V; Zebisch, K | 1 |
| Rando, RR | 1 |
| Grula, EA; Grula, MM | 1 |
| Beart, PM; Conway, EL; Manallack, DT; Mercer, LD; O'Shea, RD | 1 |
| Bismut, H; Plas, C | 1 |
| Cler, J; Emmett, MR; Iyengar, S; Mick, S; Rao, TS; Wood, PL | 1 |
| Kikuchi, G; Yoshida, T | 1 |
| Asghar, SS; Harold, FM; Levin, E | 1 |
| Clark, VL; Young, FE | 1 |
| Veerkamp, JH | 1 |
| Kandler, O; Miller, I; Plapp, R | 1 |
| Reizin, FN; Zeitlyonok, NA | 1 |
| Cosloy, SD | 1 |
| Evered, DF | 1 |
| Bulgakova, VG; Polin, AN; Silaev, AB; Teplan, I | 1 |
| Perkins, HR | 1 |
| Gould, GW | 1 |
| David, HL | 3 |
| Grula, EA; King, RD | 1 |
| Carpenter, CV; Neuhaus, FC | 1 |
| Braunstein, AE; Goryachenkova, EV; Tolosa, EA; Willhardt, IH; Yefremova, LL | 1 |
| Bukin, IuV; Raushenbakh, MO; Sergeev, AV | 1 |
| Abbott, EH; Martell, AE | 1 |
| Petit, JF; Söll, D; Strominger, JL | 1 |
| Sheehan, TG; Tully, ER | 1 |
| Baran, H; Hönack, D; Löscher, W; Rundfeldt, C; Wlaź, P | 1 |
| Bismut, H; Capeau, J; Caron, M; Coudray-Lucas, C | 1 |
| Matsui, K; Nishikawa, T; Saigoh, K; Takahashi, K; Wada, K | 1 |
| Semba, J | 1 |
| Abi-Saab, D; Bennett, A; Cassello, K; Charney, DS; D'Souza, DC; Gil, R; Karper, LP; Krystal, JH; Morrissey, K; Sturwold, R; White, J; Zuzarte, E | 1 |
| Kovács, P | 1 |
| Javitt, DC | 1 |
| Azzouz, N; Cesbron-Delauw, MF; Dubremetz, JF; Gerold, P; Rauscher, B; Schwarz, RT | 1 |
| LYNCH, JL; NEUHAUS, FC | 1 |
| DURHAM, NN; FERGUSON, D; JACOBS, CD | 1 |
| Hayashi, H; Ikushiro, H; Kagamiyama, H | 1 |
| Johnson, MS; Moretti, L; Pentikäinen, OT; Settimo, L | 1 |
| Anfora, AT; Welch, RA | 1 |
| Hammonds, MD; Kee, BS; Shim, SS | 1 |
| Fujita, Y; Hashimoto, K; Hashimoto, T; Iyo, M; Kanahara, N; Kohno, M; Matsuzawa, D; Ohgake, S; Shimizu, E; Shirayama, Y | 1 |
| Adams, E; Bockx, L; Dragovic, S; Hoogmartens, J; Pendela, M; Van Schepdael, A | 1 |
| Moskal, JR; Stanton, PK; Sullivan, JA; Zhang, XL | 1 |
| Chang, WT; Cheng, LY; Cherng, CG; Chuang, JY; Kao, GS; Lee, YS; Yang, FY; Yu, L | 1 |
| Amaral, OB; Bado, P; de Oliveira, RV; Madeira, C; Maretti, L; Moulin, TC; Panizzutti, R; Vargas-Lopes, C; Wasilewska-Sampaio, AP | 1 |
| Candéa, AL; Carvalho, SA; da Silva, EF; de Souza, MV; Feitosa, Lde O; Henriques, Md; Kaiser, CR; Lourenço, MC; Nogueira, TC; Pinheiro, AC | 1 |
| Hashimoto, K; Horio, M; Mori, H | 1 |
| Camp, M; Debrouse, L; Grant, SG; Gunduz-Cinar, O; Holmes, A; Hurd, B; Kiselycznyk, C; Mishina, M; Plitt, A; Todaro, A | 1 |
| Kumagai, T; Matoba, Y; Noda, M; Oda, K; Sugiyama, M | 1 |
| Kumagai, T; Matoba, Y; Noda, M; Oda, K; Sugiyama, M; Uda, N | 1 |
| Bonci, A; Hopf, FW; Lei, K; Messing, RO; Seif, T; Simms, JA; Wegner, S | 1 |
| Kumagai, T; Matoba, Y; Oda, K; Sugiyama, M; Uda, N | 1 |
| Billiras, RI; Dekeyne, A; Fone, KCF; Gobert, A; Millan, MJ; Rivet, JM; Sicard, DI; Watson, DJG | 1 |
| Matoba, Y; Oda, K; Sakaguchi, T | 1 |
| Balaram, A; Conrad, WH; Dejneka, S; McMahon, M; Najibi, Z; Pawlowicz, P; Robbins, L | 1 |
4 review(s) available for serine and cycloserine
| Article | Year |
|---|---|
Composition of bacterial cell walls in relation to antibiotic action.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacitracin; Bacteria; Carbamates; Cell Wall; Cephalosporins; Cycloserine; Escherichia coli; Glucosamine; Lipid Metabolism; Lysostaphin; Nucleotides; Penicillins; Peptides; Ristocetin; Serine; Staphylococcus; Vancomycin | 1969 |
[Glycine therapy of schizophrenia; its rationale and a review of clinical trials].
Topics: Acetamides; Alanine; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Cycloserine; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Humans; Prodrugs; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine | 1998 |
Treatment of negative and cognitive symptoms.
Topics: Antimetabolites; Antipsychotic Agents; Cognition Disorders; Cycloserine; Glycine; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Serine; Treatment Outcome | 1999 |
Potentiation of the NMDA receptor in the treatment of schizophrenia: focused on the glycine site.
Topics: Acetamides; Alanine; Antipsychotic Agents; Clozapine; Cognition; Cycloserine; Dopamine Agents; Drug Synergism; Drug Therapy, Combination; Glycine; Glycine Agents; Glycine Plasma Membrane Transport Proteins; Humans; Monoamine Oxidase Inhibitors; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Sarcosine; Schizophrenia; Schizophrenic Psychology; Serine | 2008 |
1 trial(s) available for serine and cycloserine
| Article | Year |
|---|---|
IV glycine and oral D-cycloserine effects on plasma and CSF amino acids in healthy humans.
Topics: Acoustic Stimulation; Administration, Oral; Adult; Amino Acids; Antimetabolites; Biological Availability; Cycloserine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glycine; Humans; Injections, Intravenous; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Serine | 2000 |
51 other study(ies) available for serine and cycloserine
| Article | Year |
|---|---|
Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).
Topics: Amino Acid Transport Systems; Caco-2 Cells; Endocytosis; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Substrate Specificity; Symporters | 2011 |
On the mechanism of action of antibiotics which act as irreversible enzyme inhibitors.
Topics: Alanine; Anti-Bacterial Agents; Asparagine; Azaserine; Azo Compounds; Carbamates; Catalysis; Cell Wall; Cephalosporins; Cycloserine; Diazooxonorleucine; Enzyme Inhibitors; Glutamine; Models, Chemical; Models, Molecular; Penicillins; Purines; Pyridoxal Phosphate; Pyrimidines; Racemases and Epimerases; Serine | 1975 |
Requirement for pantothenate for filament formation by Erwinia carotovora.
Topics: Aspartic Acid; Cell Division; Cycloserine; Erwinia; Pantothenic Acid; Penicillins; Radiation Effects; Salicylates; Serine; Stereoisomerism; Ultraviolet Rays; Vancomycin | 1976 |
Evidence for heterogenous glycine domains but conserved multiple states of the excitatory amino acid recognition site of the NMDA receptor: regional binding studies with [3H]glycine and [3H]L-glutamate.
Topics: Animals; Autoradiography; Binding, Competitive; Cerebellar Cortex; Cerebral Cortex; Cycloserine; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Kynurenic Acid; Ligands; Male; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Serine | 1991 |
Role of serine biosynthesis and its utilization in the alternative pathway from glucose to glycogen during the response to insulin in cultured foetal-rat hepatocytes.
Topics: Animals; Cells, Cultured; Cycloserine; Fetus; Glucose; Glycogen; Insulin; Liver; Pyruvates; Rats; Rats, Inbred Strains; Serine; Transaminases | 1991 |
In vivo modulation of the N-methyl-D-aspartate receptor complex by D-serine: potentiation of ongoing neuronal activity as evidenced by increased cerebellar cyclic GMP.
Topics: Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Cycloserine; Dibenzocycloheptenes; Dizocilpine Maleate; Male; Mice; N-Methylaspartate; Neurons; Piperazines; Pyrrolidinones; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine | 1989 |
Significance of the glycine cleavage system in glycine and serine catabolism in avian liver.
Topics: Ammonium Chloride; Animals; Arylformamidase; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Chickens; Columbidae; Cycloserine; Cysteine; Enzyme Activation; Folic Acid; Glycine; Hydroxylamines; Hypoxanthines; L-Serine Dehydratase; Liver; Male; Mitochondria, Liver; NAD; NADP; Oxidoreductases; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Semicarbazides; Serine; Species Specificity; Subcellular Fractions; Transferases; Uric Acid | 1971 |
Accumulation of neutral amino acids by Streptococcus faecalis. Energy coupling by a proton-motive force.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Biological Transport, Active; Carbon Radioisotopes; Carboxylic Acids; Cycloserine; Dicyclohexylcarbodiimide; Energy Metabolism; Enterococcus faecalis; Glycine; Glycolysis; Hydrogen-Ion Concentration; Kinetics; Membrane Potentials; Models, Biological; Mutation; Polycyclic Compounds; Potassium; Serine; Sodium; Threonine; Time Factors; Valinomycin | 1973 |
Active transport of D-alanine and related amino acids by whole cells of Bacillus subtilis.
Topics: Alanine; Amino Acids; Azides; Bacillus subtilis; Biological Transport, Active; Carbon Radioisotopes; Cycloserine; Depression, Chemical; Electron Transport; Glycine; Kinetics; Serine; Stereoisomerism | 1974 |
The structure of the cell wall peptidoglycan of Bifidobacterium bifidum var. pennsylvanicus.
Topics: Alanine; Amino Acids; Ammonia; Asparagine; Cell Wall; Chromatography, Gel; Chromatography, Paper; Cycloserine; Dinitrophenols; Electrophoresis; Fluorine; Glucosamine; Glutamine; Glycosaminoglycans; Hydrazines; Hydrolysis; Lactobacillus; Models, Structural; Muramidase; Nucleoside Diphosphate Sugars; Ornithine; Paper; Peptides; Polysaccharides, Bacterial; Serine; Species Specificity; Stereoisomerism; Uracil Nucleotides | 1971 |
[Isolation and identification of a serine-containing UDP-muramyltripeptide from Butyribacterium rettgeri].
Topics: Amino Acid Sequence; Amino Sugars; Chromatography, Paper; Cycloserine; Eubacterium; Glutamates; Ornithine; Peptides; Serine; Spectrophotometry; Ultraviolet Rays; Uracil Nucleotides | 1968 |
Physiology of interferonogenesis. II. Mechanism of action of alanine and serine on interferon production in chick embryo fibroblast cultures.
Topics: Alanine; Animals; Antimetabolites; Chick Embryo; Chloromercuribenzoates; Culture Techniques; Cycloserine; Dinitrophenols; Fibroblasts; Interferons; Iodoacetates; Orthomyxoviridae; Serine; Sodium; Stereoisomerism | 1971 |
D-serine transport system in Escherichia coli K-12.
Topics: Alanine; Biological Transport, Active; Carbon Isotopes; Chromosome Mapping; Cycloserine; Drug Resistance, Microbial; Escherichia coli; Genes; Genetic Linkage; Glycine; L-Serine Dehydratase; Membrane Transport Proteins; Mutation; Recombination, Genetic; Serine; Stereoisomerism | 1973 |
Permeability of human buccal mucosa to an amino acid analogue, the antibiotic D-cycloserine.
Topics: Alanine; Cheek; Cycloserine; Humans; Hydrogen-Ion Concentration; Methionine; Mouth Mucosa; Proline; Serine | 1972 |
[Study of antibacterial properties of alpha-alkylserines and 4-alkyl substituted derivatives of cycloserine].
Topics: Alanine; Alkylation; Anti-Bacterial Agents; Bacteria; Cycloserine; Escherichia coli; Leucine; Mycobacterium; Serine; Staphylococcus | 1968 |
Stimulation of L-alanine-induced germination of Bacillus cereus spores by D-cycloserine and O-carbamyl-D-serine.
Topics: Alanine; Bacillus cereus; Cycloserine; Hot Temperature; Serine; Spores | 1966 |
Effect of O-carbamyl-D-serine on the growth of mycobacterium tuberculosis.
Topics: Alanine; Amino Acids; Amino Sugars; Binding Sites; Carbamates; Culture Media; Cycloserine; Drug Synergism; Ligases; Mycobacterium tuberculosis; Receptors, Drug; Serine | 1970 |
Resistance to D-cycloserine in the tubercle bacilli: mutation rate and transport of alanine in parental cells and drug-resistant mutants.
Topics: Alanine; Carbamates; Carbon Isotopes; Cycloserine; Drug Resistance, Microbial; Genetics, Microbial; Glycine; Membrane Transport Proteins; Mutation; Mycobacterium tuberculosis; Serine | 1971 |
Condition of cell-wall mucopeptide in dividing and non-dividing cells of Micrococcus lysodeikticus dis-IIp + .
Topics: Alanine; Amino Acids; Amino Sugars; Carbon Isotopes; Cell Division; Cell Wall; Chromatography, Thin Layer; Cycloserine; Histocytochemistry; Hydroxylamines; Lactones; Micrococcus; Microscopy, Electron; Mitomycins; Penicillins; Peptide Biosynthesis; Peptides; Serine; Spermine; Stereoisomerism; Vancomycin | 1972 |
Enzymatic synthesis of D-alanyl-D-alanine. Two binding modes for product on D-alanine: D-alanine ligase (ADP).
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Cycloserine; Dipeptides; Drug Stability; Hot Temperature; Ligases; Magnesium; Manganese; Phosphorus Isotopes; Protein Binding; Serine; Valine | 1972 |
Specificity and some other properties of liver serine sulphhydrase: evidence for its identity with cystathionine -synthase.
Topics: Acetates; Alanine; Amino Acids; Animals; Catalysis; Chickens; Chlorine; Chromatography, Gel; Chromatography, Paper; Cycloserine; Cysteamine; Cysteine; Electrophoresis, Paper; Glycolates; Homocysteine; Hydro-Lyases; Hydroxylamines; Isoelectric Focusing; Kinetics; L-Serine Dehydratase; Liver; Mercaptoethanol; Nitriles; Penicillamine; Propionates; Pyridoxal Phosphate; Rats; Serine; Species Specificity; Sulfhydryl Compounds; Sulfides; Sulfuric Acids; Thioglycolates | 1971 |
[Study of serine hydroxymethyltransferase in experimental leukemias].
Topics: Animals; Ascitic Fluid; Cycloserine; Friend murine leukemia virus; Hydrazines; Hydroxylamines; In Vitro Techniques; Isoniazid; Leukemia, Experimental; Leukemia, Myeloid; Liver; Mice; Mice, Inbred Strains; Semicarbazides; Serine; Spleen; Thiosemicarbazones; Transferases | 1971 |
Pyridoxine and pyridoxal analogs. 13. A nuclear magnetic resonance study of the condensation of polyfunctional amino acids with pyridoxal.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Cycloserine; Histidine; Homocysteine; Homocystine; Imidazoles; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Serine; Threonine | 1970 |
Susceptibility of mycobacterium intracellulare to O-carbamyl-D-serine.
Topics: Amino Acids; Carbamates; Culture Media; Cycloserine; Drug Synergism; Mycobacterium; Serine | 1970 |
Biosynthesis of the peptidoglycan of bacterial cell walls. VII. Incorporation of serine and glycine into interpeptide bridges in Staphylococcus epidermidis.
Topics: Alcohols; Bacitracin; Carbon Isotopes; Cell Wall; Chloramphenicol; Chlortetracycline; Chromatography, Ion Exchange; Cycloserine; Erythromycin; Glycoproteins; Lincomycin; Novobiocin; Penicillins; Peptide Biosynthesis; Polysaccharides, Bacterial; Puromycin; Ristocetin; Serine; Staphylococcus; Streptomycin; Surface-Active Agents; Tritium; Vancomycin | 1968 |
Purine biosynthesis de novo in rat skeletal muscle.
Topics: Adenine; Adenosine; Animals; Azaserine; Cycloserine; Female; Formates; Glycine; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Male; Muscles; Purines; Rats; Rats, Inbred Strains; Serine | 1983 |
Anticonvulsant effects of the glycine/NMDA receptor ligands D-cycloserine and D-serine but not R-(+)-HA-966 in amygdala-kindled rats.
Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Cycloserine; Dizocilpine Maleate; Electric Stimulation; Epilepsy, Complex Partial; Female; Glycine; Kindling, Neurologic; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine | 1994 |
Glucose contribution to nucleic acid base synthesis in proliferating hepatoma cells: a glycine-biosynthesis-mediated pathway.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cells, Cultured; Cycloserine; Enzyme Inhibitors; Glucose; Glycine; Glycogen; Glycolysis; Insulin; Lactic Acid; Nucleic Acids; Nucleotides; Proteins; Rats; Rats, Inbred Strains; Serine; Transaminases | 1995 |
The stereo-specific effect of D-serine ethylester and the D-cycloserine in ataxic mutant mice.
Topics: Animals; Cerebellum; Cycloserine; Cytarabine; Extracellular Space; Male; Mice; Mice, Inbred ICR; Mice, Neurologic Mutants; Microdialysis; Serine; Spinocerebellar Degenerations; Stereoisomerism | 1998 |
The effect of beta-chloro D-alanine and L-cycloserine on the serine, phosphorus and palmitic acid uptake and metabolism of Tetrahymena lipids.
Topics: Acyltransferases; Animals; beta-Alanine; Ceramides; Cycloserine; Palmitic Acid; Phospholipids; Serine; Serine C-Palmitoyltransferase; Tetrahymena pyriformis | 1999 |
Evidence for de novo sphingolipid biosynthesis in Toxoplasma gondii.
Topics: Animals; Antimetabolites; Ceramides; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cycloserine; Galactose; Glycoside Hydrolases; Serine; Sphingolipids; Toxoplasma; Tritium | 2002 |
THE ENZYMATIC SYNTHESIS OF D-ALANYL-D-ALANINE. 3. ON THE INHIBITION OF D-ALANYL-D-ALANINE SYNTHETASE BY THE ANTIBIOTIC D-CYCLOSERINE.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Anti-Bacterial Agents; Carbon Isotopes; Chromatography; Cycloserine; Enterococcus faecalis; Enzyme Inhibitors; Ligases; Magnesium; Oxazoles; Pharmacology; Potassium; Research; Serine; Threonine | 1964 |
RELATIONSHIP OF A BETA-ALANINE-PYRUVIC AMINOTRANSFERASE TO REVERSAL OF D-SERINE INHIBITION OF GROWTH.
Topics: Alanine; Alanine Transaminase; Aspartic Acid; beta-Alanine; Cycloserine; Flavobacterium; Ketoglutaric Acids; Mitomycin; Mitomycins; Pantothenic Acid; Penicillins; Pharmacology; Pyridoxal Phosphate; Pyruvates; Research; Serine; Transaminases; Vancomycin | 1964 |
Reactions of serine palmitoyltransferase with serine and molecular mechanisms of the actions of serine derivatives as inhibitors.
Topics: Acyltransferases; beta-Alanine; Circular Dichroism; Cycloserine; Enzyme Inhibitors; Escherichia coli; Lactic Acid; Phosphoserine; Propanolamines; Propylene Glycols; Recombinant Proteins; Serine; Serine C-Palmitoyltransferase; Spectrometry, Fluorescence; Spectrophotometry; Sphingomonas; Stereoisomerism; Substrate Specificity | 2004 |
Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands.
Topics: Alanine; Amino Acid Sequence; Animals; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cycloserine; Databases as Topic; Escherichia coli; Excitatory Amino Acid Antagonists; Glycine; Humans; Hydrogen Bonding; Indoles; Kynurenic Acid; Ligands; Mice; Models, Chemical; Models, Molecular; Molecular Sequence Data; Potassium Channels; Proline; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sequence Homology, Amino Acid; Serine; Threonine; Tryptophan; Water | 2004 |
DsdX is the second D-serine transporter in uropathogenic Escherichia coli clinical isolate CFT073.
Topics: Alanine; Amino Acid Transport Systems; Biological Transport; Culture Media; Cycloserine; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Glycine; Kinetics; Membrane Transport Proteins; Models, Biological; Serine; Threonine | 2006 |
Glycine and D: -serine, but not D: -cycloserine, attenuate prepulse inhibition deficits induced by NMDA receptor antagonist MK-801.
Topics: Animals; Antimetabolites; Chromatography, High Pressure Liquid; Cycloserine; Data Interpretation, Statistical; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Injections, Intraperitoneal; Male; Mice; Microdialysis; Quinolones; Reflex, Startle; Serine | 2008 |
Development of a liquid chromatographic method for the determination of related substances and assay of d-cycloserine.
Topics: Acetonitriles; Antibiotics, Antitubercular; Biological Assay; Buffers; Caprylates; Capsules; Chromatography, Liquid; Cycloserine; Dimerization; Drug Stability; Hydrogen-Ion Concentration; Molecular Structure; Phosphates; Potassium Compounds; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity; Serine; Solvents; Spectrophotometry, Ultraviolet; Technology, Pharmaceutical; Temperature; Time Factors; Water | 2008 |
A NMDA receptor glycine site partial agonist, GLYX-13, simultaneously enhances LTP and reduces LTD at Schaffer collateral-CA1 synapses in hippocampus.
Topics: Animals; Antimetabolites; Calcium; Cycloserine; Data Interpretation, Statistical; Excitatory Postsynaptic Potentials; Extracellular Space; Hippocampus; Long-Term Potentiation; Male; Memory; Neuronal Plasticity; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Synapses | 2008 |
D-cycloserine, sarcosine and D-serine diminish the expression of cocaine-induced conditioned place preference.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Cycloserine; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Memory; Mice; Mice, Inbred C57BL; Sarcosine; Serine; Time Factors | 2013 |
Effects of low-dose D-serine on recognition and working memory in mice.
Topics: Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Cycloserine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Male; Maze Learning; Memory, Short-Term; Mice; Mice, Inbred BALB C; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Serine; Time Factors | 2011 |
Synthesis and antitubercular activity of new L-serinyl hydrazone derivatives.
Topics: Antitubercular Agents; Cell Survival; Cycloserine; Dose-Response Relationship, Drug; Hydrazones; Macrophages; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium bovis; Mycobacterium tuberculosis; Serine; Stereoisomerism; Structure-Activity Relationship | 2011 |
Is D-cycloserine a prodrug for D-serine in the brain?
Topics: Animals; Brain; Cycloserine; Humans; Meta-Analysis as Topic; Serine | 2013 |
Probing the modulation of acute ethanol intoxication by pharmacological manipulation of the NMDAR glycine co-agonist site.
Topics: Alcoholic Intoxication; Animals; Ataxia; Cycloserine; Disease Models, Animal; Disks Large Homolog 4 Protein; Dizocilpine Maleate; Drug Therapy, Combination; Glycine Plasma Membrane Transport Proteins; Guanylate Kinases; Hypothermia; Kynurenic Acid; Magnesium; Male; Membrane Proteins; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Quinolones; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reflex, Righting; Sarcosine; Serine | 2013 |
Crystallographic study to determine the substrate specificity of an L-serine-acetylating enzyme found in the D-cycloserine biosynthetic pathway.
Topics: Acetyltransferases; Bacterial Proteins; Crystallography, X-Ray; Cycloserine; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Protein Conformation; Serine; Streptomyces; Substrate Specificity; Viral Proteins | 2013 |
Establishment of an in vitro D-cycloserine-synthesizing system by using O-ureido-L-serine synthase and D-cycloserine synthetase found in the biosynthetic pathway.
Topics: Antitubercular Agents; Biosynthetic Pathways; Chromatography, Thin Layer; Cycloserine; Ligases; Multigene Family; Serine; Streptomyces; Substrate Specificity | 2013 |
D-Serine and D-Cycloserine Reduce Compulsive Alcohol Intake in Rats.
Topics: Alcohol Drinking; Animals; Compulsive Behavior; Cycloserine; Ethanol; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Prefrontal Cortex; Rats; Rats, Wistar; Saccharin; Serine; Valine | 2015 |
The structural and mutational analyses of O-ureido-L-serine synthase necessary for D-cycloserine biosynthesis.
Topics: Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Biocatalysis; Catalytic Domain; Conserved Sequence; Cycloserine; Cysteine Synthase; Enzyme Stability; Hydrogen Bonding; Hydroxyurea; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutant Proteins; Protein Conformation; Recombinant Proteins; Sequence Alignment; Serine; Streptomyces; Substrate Specificity | 2015 |
Comparative Pro-cognitive and Neurochemical Profiles of Glycine Modulatory Site Agonists and Glycine Reuptake Inhibitors in the Rat: Potential Relevance to Cognitive Dysfunction and Its Management.
Topics: Amino Acids; Animals; Autism Spectrum Disorder; Cognition; Cognition Disorders; Cycloserine; Dose-Response Relationship, Drug; Freezing Reaction, Cataleptic; Glycine; Glycine Agents; Male; Memory, Short-Term; Motor Activity; Neurotransmitter Uptake Inhibitors; Nootropic Agents; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Sarcosine; Schizophrenia; Scopolamine; Serine; Social Behavior | 2020 |
Crystal structure of O-ureidoserine racemase found in the d-cycloserine biosynthetic pathway.
Topics: Biosynthetic Pathways; Crystallography, X-Ray; Cycloserine; Multigene Family; Racemases and Epimerases; Serine | 2022 |
Heterologous production of the D-cycloserine intermediate O-acetyl-L-serine in a human type II pulmonary cell model.
Topics: Acetyl Coenzyme A; Anti-Bacterial Agents; COVID-19; Cycloserine; Humans; Serine; Tuberculosis | 2023 |