serine has been researched along with cephalosporin c in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (8.82) | 18.7374 |
| 1990's | 8 (23.53) | 18.2507 |
| 2000's | 11 (32.35) | 29.6817 |
| 2010's | 6 (17.65) | 24.3611 |
| 2020's | 6 (17.65) | 2.80 |
| Authors | Studies |
|---|---|
| Rando, RR | 1 |
| Bush, K; Dougherty, TJ; Gougoutas, JZ; Malley, MF; Ohringer, S; Singer, SB; Sowek, JA | 1 |
| Fink, AL; Tan, AK; Virden, R | 1 |
| Anwar, H; Brown, MR; Kadurugamuwa, JL; Zak, O | 1 |
| Perkins, HR | 1 |
| Dubus, A; Frère, JM; Normark, S; Raquet, X; Wilkin, JM | 1 |
| Imtiaz, U; Lerner, SA; Manavathu, EK; Mobashery, S | 1 |
| Huletsky, A; Knox, JR; Levesque, RC | 1 |
| Courvalin, P; Frère, JM; Goussard, S; Lamotte-Brasseur, J; Raquet, X; Vanhove, M | 1 |
| Gazouli, M; Sidorenko, SV; Tzelepi, E; Tzouvelekis, LS | 1 |
| Clairoux, N; Huletsky, A; Knox, JR; Levesque, RC; Sanschagrin, F; Trépanier, S | 1 |
| Amicosante, G; Bianchi, B; Caravelli, B; del Tavio-Perez, MM; Franceschini, N; Gizzi, G; Mancinelli, A; Perilli, M; Segatore, B; Setacci, D | 1 |
| Anderson, JC; Magliery, TJ; Schultz, PG | 1 |
| Petersen, EI; Schwab, H; Sölkner, B; Stubenrauch, G; Valinger, G | 1 |
| Carenbauer, AL; Crowder, MW; Garrity, JD; Periyannan, G; Yates, RB | 1 |
| Methner, U; Rabsch, W; Reissbrodt, R; Tschäpe, H; Voigt, W; Williams, PH | 1 |
| Degrassi, G; Guarnaccia, C; Krastanova, I; Lamba, D; Zahariev, S | 1 |
| Ke, YY; Lin, TH | 1 |
| Feng, D; He, M; Li, R | 1 |
| Galleni, M; Mammeri, H; Nordmann, P | 1 |
| Buynak, JD; Ganta, SR; Pagadala, SR; Perumal, S; Pratt, RF; Samuelsen, O; Spencer, J | 1 |
| Bethel, CR; Bonomo, RA; Carey, PR; Kalp, M | 1 |
| Aepfelbacher, M; Heisig, P; Hentschke, M; Kotsakis, SD; Miriagou, V; Wolters, M | 1 |
| Deng, Z; Huang, X; Yin, J; Zhao, G | 1 |
| Anandan, A; Flematti, G; Golden, E; Molla, G; Paterson, R; Pollegioni, L; Rosini, E; Tie, WJ; Vrielink, A | 1 |
| Andersson, I; Blikstad, C; Demetriades, M; Dubus, A; Généreux, C; Hopkinson, RJ; Iqbal, A; Ivison, D; Kershaw, NJ; Lloyd, AJ; McDonough, MA; Roper, DI; Schofield, CJ; Valegård, K | 1 |
| Bjerga, GE; Edvardsen, KS; Leiros, HK; Samuelsen, Ø | 1 |
| Amicosante, G; Bottoni, C; Celenza, G; Colapietro, M; Galleni, M; Kerff, F; Marcoccia, F; Matagne, A; Mercuri, PS; Perilli, M; Sabatini, A | 1 |
| Abdelraouf, K; Almarzoky Abuhussain, S; Nicolau, DP | 1 |
| Abdelraouf, K; Gill, CM; Nicolau, DP | 1 |
| Adapa, SR; Atlas, ZD; Chen, Y; Eswara, PJ; Gatdula, JR; Gelis, I; Gongora, MV; Hammond, LR; Jiang, RHY; Keramisanou, D; Lewandowski, EM; Marty, MT; Morgan, RT; Sacco, MD; Sun, X; Townsend, JA; Wang, J; Wang, S; Zhang, X | 1 |
| Djorić, D; Kristich, CJ; Little, J; Minton, NE | 1 |
| Bachta, KER; Bertucci, HK; Brunzelle, JS; Gatesy, SWM; Hauser, AR; Lebrun-Corbin, M; Minasov, G; Ozer, EA; Pincus, NB; Rosas-Lemus, M; Satchell, KJF; Shuvalova, LA | 1 |
| Mensa, J; Soriano, A | 1 |
2 review(s) available for serine and cephalosporin c
| Article | Year |
|---|---|
Composition of bacterial cell walls in relation to antibiotic action.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacitracin; Bacteria; Carbamates; Cell Wall; Cephalosporins; Cycloserine; Escherichia coli; Glucosamine; Lipid Metabolism; Lysostaphin; Nucleotides; Penicillins; Peptides; Ristocetin; Serine; Staphylococcus; Vancomycin | 1969 |
Mechanism of action of cefiderocol.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Cattle; Cefepime; Cefiderocol; Ceftazidime; Cephalosporins; Gram-Negative Bacteria; Iron; Quinolones; Serine; Tetracyclines | 2022 |
32 other study(ies) available for serine and cephalosporin c
| Article | Year |
|---|---|
On the mechanism of action of antibiotics which act as irreversible enzyme inhibitors.
Topics: Alanine; Anti-Bacterial Agents; Asparagine; Azaserine; Azo Compounds; Carbamates; Catalysis; Cell Wall; Cephalosporins; Cycloserine; Diazooxonorleucine; Enzyme Inhibitors; Glutamine; Models, Chemical; Models, Molecular; Penicillins; Purines; Pyridoxal Phosphate; Pyrimidines; Racemases and Epimerases; Serine | 1975 |
Substitution of lysine at position 104 or 240 of TEM-1pTZ18R beta-lactamase enhances the effect of serine-164 substitution on hydrolysis or affinity for cephalosporins and the monobactam aztreonam.
Topics: Aztreonam; beta-Lactamases; Binding Sites; Cephalosporins; Escherichia coli; Hydrolysis; Kinetics; Lysine; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Protein Conformation; Serine; Substrate Specificity | 1991 |
Cryoenzymology of staphylococcal beta-lactamase: trapping a serine-70-linked acyl-enzyme.
Topics: Acylation; beta-Lactamases; Cephalosporins; Chromatography, High Pressure Liquid; Enzyme Stability; Freezing; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Penicillins; Protein Conformation; Serine; Solvents; Staphylococcus; Temperature | 1990 |
Effect of subinhibitory concentrations of cephalosporins on surface properties and siderophore production in iron-depleted Klebsiella pneumoniae.
Topics: Bacterial Proteins; Cell Membrane; Cephalosporins; Culture Media; Electrophoresis, Polyacrylamide Gel; Enterobactin; Iron; Iron Chelating Agents; Klebsiella pneumoniae; Microbial Sensitivity Tests; Serine; Siderophores; Surface Properties; Time Factors | 1985 |
Catalytic mechanism of active-site serine beta-lactamases: role of the conserved hydroxy group of the Lys-Thr(Ser)-Gly triad.
Topics: Amino Acid Sequence; Base Sequence; beta-Lactamases; Binding Sites; Catalysis; Cephalosporins; Enzyme Stability; Escherichia coli; Hot Temperature; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Penicillins; Salmonella typhimurium; Serine; Structure-Activity Relationship; Substrate Specificity | 1994 |
Critical hydrogen bonding by serine 235 for cephalosporinase activity of TEM-1 beta-lactamase.
Topics: Base Sequence; beta-Lactamases; Cephalosporinase; Cephalosporins; Circular Dichroism; Escherichia coli; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis; Serine | 1993 |
Role of Ser-238 and Lys-240 in the hydrolysis of third-generation cephalosporins by SHV-type beta-lactamases probed by site-directed mutagenesis and three-dimensional modeling.
Topics: Amino Acid Sequence; Bacillus; Base Sequence; beta-Lactamases; Binding Sites; Cefotaxime; Ceftazidime; Cephalosporins; Citrobacter freundii; Hydrolysis; Lysine; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Protein Structure, Secondary; Recombinant Proteins; Serine; Streptomyces | 1993 |
Stability of TEM beta-lactamase mutants hydrolyzing third generation cephalosporins.
Topics: Arginine; beta-Lactamases; Cephalosporin Resistance; Cephalosporins; Enzyme Stability; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Models, Chemical; Models, Molecular; Mutation; Protein Conformation; Protein Denaturation; Protein Folding; Serine; Temperature; Thermodynamics; Trypsin | 1995 |
Sequence of the gene encoding a plasmid-mediated cefotaxime-hydrolyzing class A beta-lactamase (CTX-M-4): involvement of serine 237 in cephalosporin hydrolysis.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Cefotaxime; Cephalosporins; Genes, Bacterial; Hydrolysis; Molecular Sequence Data; Plasmids; Salmonella typhimurium; Serine | 1998 |
Structure-function studies of Ser-289 in the class C beta-lactamase from Enterobacter cloacae P99.
Topics: Bacterial Proteins; beta-Lactamases; Catalysis; Cefaclor; Cefazolin; Cephalosporins; Crystallography, X-Ray; Electrophoresis, Polyacrylamide Gel; Enterobacter cloacae; Escherichia coli; Hydrolysis; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Mutagenesis, Site-Directed; Plasmids; Protein Conformation; Serine; Structure-Activity Relationship | 1999 |
Ceftibuten stability to active-site serine and metallo-beta-lactamases.
Topics: beta-Lactamases; Binding Sites; Catalysis; Ceftibuten; Cephalosporins; Drug Resistance, Microbial; Drug Stability; Hydrolysis; Serine | 2001 |
Expanding the genetic code: selection of efficient suppressors of four-base codons and identification of "shifty" four-base codons with a library approach in Escherichia coli.
Topics: Amino Acid Sequence; Ampicillin; Anticodon; Base Pairing; Base Sequence; beta-Lactamases; Cephalosporins; Codon; Escherichia coli; Frameshift Mutation; Gene Expression Regulation, Bacterial; Gene Library; Genes, Reporter; Genetic Code; Molecular Sequence Data; Mutagenesis; Protein Biosynthesis; RNA, Transfer; RNA, Transfer, Ser; Serine; Substrate Specificity; Suppression, Genetic | 2001 |
A novel esterase from Burkholderia gladioli which shows high deacetylation activity on cephalosporins is related to beta-lactamases and DD-peptidases.
Topics: Acetylation; Amino Acid Sequence; Base Sequence; beta-Lactamases; Burkholderia; Carboxypeptidases; Cephalosporins; Cloning, Molecular; DNA Primers; Escherichia coli; Hydrolysis; Molecular Sequence Data; Mutagenesis, Site-Directed; Open Reading Frames; Promoter Regions, Genetic; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases; Serine-Type D-Ala-D-Ala Carboxypeptidase | 2001 |
Probing substrate binding to metallo-beta-lactamase L1 from Stenotrophomonas maltophilia by using site-directed mutagenesis.
Topics: Asparagine; beta-Lactamases; Binding Sites; Carbapenems; Cephalosporins; Computational Biology; Isoleucine; Kinetics; Metals; Models, Molecular; Mutagenesis, Site-Directed; Penicillins; Phenylalanine; Protein Binding; Serine; Stenotrophomonas maltophilia; Tyrosine | 2002 |
Role of receptor proteins for enterobactin and 2,3-dihydroxybenzoylserine in virulence of Salmonella enterica.
Topics: Animals; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; Carrier Proteins; Cephalosporins; Chickens; Enterobactin; Female; Mice; Mice, Inbred BALB C; Poultry Diseases; Receptors, Cell Surface; Salmonella enteritidis; Salmonella Infections, Animal; Salmonella typhimurium; Serine; Serum; Virulence | 2003 |
Heterologous expression, purification, crystallization, X-ray analysis and phasing of the acetyl xylan esterase from Bacillus pumilus.
Topics: Acetylesterase; Alanine; Bacillus; Carbohydrate Conformation; Carbohydrate Sequence; Carbohydrates; Catalysis; Cell Wall; Cephalosporins; Chromatography, Gel; Crystallography, X-Ray; Escherichia coli; Esterases; Light; Lithium Chloride; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Recombinant Proteins; Scattering, Radiation; Serine; Time Factors; X-Ray Diffraction; Xylans; Xylose | 2005 |
A theoretical study on the activation of Ser70 in the acylation mechanism of cephalosporin antibiotics.
Topics: Acylation; beta-Lactamases; Cephalosporins; Computer Simulation; Enzyme Activation; Models, Chemical; Models, Molecular; Molecular Structure; Serine | 2005 |
Theoretical study of the reaction from 6-methylidene penem to seven-membered ring intermediates.
Topics: Acylation; beta-Lactamase Inhibitors; Cephalosporins; Enzyme Inhibitors; Hydrogen; Models, Theoretical; Molecular Structure; Serine; Solvents; Sulfides; Thermodynamics; Water | 2007 |
Role of the Ser-287-Asn replacement in the hydrolysis spectrum extension of AmpC beta-lactamases in Escherichia coli.
Topics: Asparagine; Bacterial Proteins; beta-Lactamases; Cephalosporins; Escherichia coli; Escherichia coli Proteins; Hydrolysis; Microbial Sensitivity Tests; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Serine | 2009 |
Approaches to the simultaneous inactivation of metallo- and serine-beta-lactamases.
Topics: Amides; Amino Acid Motifs; beta-Lactamases; Catalytic Domain; Cephalosporins; Enzyme Inhibitors; Hydroxamic Acids; Inhibitory Concentration 50; Kinetics; Metals; Models, Chemical; Molecular Structure; Oximes; Serine | 2009 |
Why the extended-spectrum beta-lactamases SHV-2 and SHV-5 are "hypersusceptible" to mechanism-based inhibitors.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Catalytic Domain; Cephalosporins; Crystallography, X-Ray; Kinetics; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Plasmids; Serine; Spectrum Analysis, Raman; Sulbactam | 2009 |
CMY-42, a novel plasmid-mediated CMY-2 variant AmpC beta-lactamase.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Molecular Sequence Data; Plasmids; Serine; Surgical Wound Infection; Valine | 2011 |
The N-terminal nucleophile serine of cephalosporin acylase executes the second autoproteolytic cleavage and acylpeptide hydrolysis.
Topics: Amino Acid Substitution; Bacterial Proteins; Cephalosporins; Enzyme Activation; Enzyme Precursors; Hydrolysis; Mutation, Missense; Penicillin Amidase; Protein Structure, Quaternary; Protein Structure, Tertiary; Pseudomonas; Serine | 2011 |
Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity.
Topics: Amidohydrolases; Catalysis; Catalytic Domain; Cephalosporins; Crystallography, X-Ray; Kinetics; Mutation; Penicillin Amidase; Protein Conformation; Pseudomonas; Recombinant Proteins; Serine; Substrate Specificity | 2013 |
Structural and mechanistic studies of the orf12 gene product from the clavulanic acid biosynthesis pathway.
Topics: Amino Acid Motifs; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carboxypeptidases; Catalytic Domain; Cephalosporins; Clavulanic Acid; Crystallography, X-Ray; Hydrolysis; Models, Molecular; Penicillins; Protein Conformation; Protein Structure, Tertiary; Serine; Streptomyces | 2013 |
Structural and biochemical characterization of VIM-26 shows that Leu224 has implications for the substrate specificity of VIM metallo-β-lactamases.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Binding Sites; Carbapenems; Catalysis; Cephalosporins; Crystallography, X-Ray; Drug Resistance, Bacterial; Ions; Klebsiella pneumoniae; Leucine; Penicillins; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Serine; Substrate Specificity | 2015 |
Kinetic Study of Laboratory Mutants of NDM-1 Metallo-β-Lactamase and the Importance of an Isoleucine at Position 35.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Biocatalysis; Catalytic Domain; Cephalosporins; Cloning, Molecular; Escherichia coli; Gene Expression; Isoleucine; Kinetics; Models, Molecular; Mutation; Protein Structure, Secondary; Recombinant Proteins; Serine; Threonine | 2016 |
In vivo pharmacodynamics of new-generation β-lactamase inhibitor taniborbactam (formerly VNRX-5133) in combination with cefepime against serine-β-lactamase-producing Gram-negative bacteria.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Borinic Acids; Carboxylic Acids; Cefepime; Cephalosporins; Humans; Mice; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Serine | 2020 |
In vivo activity of WCK 4282 (high-dose cefepime/tazobactam) against serine β-lactamase-producing Enterobacterales and Pseudomonas aeruginosa in the neutropenic murine thigh infection model.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Escherichia coli; Mice; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Serine; Tazobactam; Thigh | 2021 |
A unique class of Zn
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Cephalosporin Resistance; Cephalosporins; Clostridioides; Clostridioides difficile; Humans; Serine; Zinc | 2022 |
GpsB Promotes PASTA Kinase Signaling and Cephalosporin Resistance in
Topics: Anti-Bacterial Agents; Cephalosporin Resistance; Cephalosporins; Enterococcus faecalis; Phosphotransferases; Protein Serine-Threonine Kinases; Serine; Signal Transduction; Threonine | 2022 |
Functional and Structural Characterization of OXA-935, a Novel OXA-10-Family β-Lactamase from Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Aspartic Acid; Azabicyclo Compounds; beta-Lactamase Inhibitors; beta-Lactamases; Ceftazidime; Cephalosporinase; Cephalosporins; Glycine; Humans; Microbial Sensitivity Tests; Phenylalanine; Pseudomonas aeruginosa; Pseudomonas Infections; Serine; Tazobactam | 2022 |