serine has been researched along with calpain in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.94) | 18.7374 |
| 1990's | 6 (17.65) | 18.2507 |
| 2000's | 18 (52.94) | 29.6817 |
| 2010's | 7 (20.59) | 24.3611 |
| 2020's | 2 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Christoph, G; Siman, R | 1 |
| Blumenthal, EJ; Malkinson, AM; Miller, AC; Stein, GH | 1 |
| Díez, JA; Elvira, M; Villalobo, A; Wang, KK | 1 |
| Arahata, K; Ishiura, S; Kawasaki, H; Miyasaka, M; Saido, TC; Sorimachi, H; Sugita, H; Suzuki, K; Toyama-Sorimachi, N | 1 |
| Aman, MJ; Henkart, PA; Leonard, WJ; Nakajima, H; Noguchi, M; Sarin, A; Shores, EW | 1 |
| Arthur, JS; Croall, DE; Dutt, P; Elce, JS | 1 |
| Nakanishi, N; Ohashi, M; Sugikawa, E; Tsunoda, S; Yazaki, N | 1 |
| Best-Belpomme, M; Boelaert, JR; Ferreira, V; Korner, M; Legrand-Poels, S; Piette, J; Schoonbroodt, S | 1 |
| de la Luz Ibarra, M; García, EJ; Jay, D; Lara, JE; Medina, MA | 1 |
| Arahata, K; Fukuda, R; Hata, S; Hayashi, Y; Ishiura, S; Karasuyama, H; Katsui, Y; Nakagawa, M; Nonaka, I; Ono, Y; Seyama, Y; Sorimachi, H; Suzuki, K; Tagawa, K; Taya, C; Toyama-Sorimachi, N; Yonekawa, H | 1 |
| Block, ER; Su, Y | 1 |
| Davies, PL; Elce, JS; Hosfield, CM; Jia, Z; Moldoveanu, T | 1 |
| Loeffler, JP; Sée, V | 1 |
| Bordone, L; Campbell, C | 1 |
| Agerholm-Larsen, B; Chen, W; Linsel-Nitschke, P; Martinez, LO; Silver, DL; Tall, AR; Wang, N | 1 |
| Elce, JS; Huynh, KK; Jia, Z; Smith, SD; Wells, A | 1 |
| Blair, HC; Bodnar, RJ; Glading, A; Potter, DA; Reynolds, IJ; Satish, L; Shiraha, H; Wells, A | 1 |
| Inanami, O; Kawahara, K; Kuwabara, M; Nakajima, T; Nomura, Y; Okuma, Y; Wakasa, T | 1 |
| García, E; Jay, D; Stracher, A | 1 |
| Chung, KC; Kim, HJ; Kim, J; Lee, CH; Lee, D; Paik, SR | 1 |
| Mosevitsky, MI; Zakharov, VV | 1 |
| Bernal, JA; Hernández, A | 1 |
| Baliova, M; Franekova, V; Jursky, F | 1 |
| Critchley, DR | 1 |
| Minchin, RF; Mitchell, DJ | 1 |
| Huang, Q; Lai, B; Li, M; Liu, S; Ma, S; Song, B; Wang, C; Xie, B | 1 |
| Feng, Y; Ge, H; Shu, X; Wang, J; Wang, X; Xia, Y; Yu, G; Zeng, K | 1 |
| Hata, S; Nishino, I; Noguchi, S; Ojima, K; Ono, Y; Sorimachi, H | 1 |
| Love, S; Miners, JS; Renfrew, R; Swirski, M | 1 |
| dos Remedios, C; Foster, DB; Li, Y; Murphy, AM; Stienen, GJ; van der Velden, J; Van Eyk, JE; Wijnker, PJ; Zhang, P | 1 |
| Heravi, A; Kass, DA; Keceli, G; Li, Y; Murphy, AM; Okumus, N; Paolocci, N; Ramirez-Correa, G; Takahashi, C; Zhang, P; Zhu, G | 1 |
| Chen, H; Fang, R; Hu, D; Jia, P; Peng, J; Rabidou, K; Shi, Y; Shi, YG; Wu, D; Wu, Z; Yu, D; Zhao, Z | 1 |
| Baliova, M; Jursky, F | 1 |
| Maitra, S; Vincent, B | 1 |
1 review(s) available for serine and calpain
| Article | Year |
|---|---|
Cdk5-p25 as a key element linking amyloid and tau pathologies in Alzheimer's disease: Mechanisms and possible therapeutic interventions.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis; Calpain; Cyclin-Dependent Kinase 5; Humans; Phosphorylation; Serine; tau Proteins; Threonine | 2022 |
33 other study(ies) available for serine and calpain
| Article | Year |
|---|---|
beta-Amyloid precursor is a PEST protein.
Topics: Amino Acid Sequence; Amyloid; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Brain Chemistry; Calpain; Glutamates; Glutamic Acid; Molecular Sequence Data; Proline; Protease Inhibitors; Protein Precursors; Rats; Serine; Threonine | 1989 |
Serine/threonine protein kinases and calcium-dependent protease in senescent IMR-90 fibroblasts.
Topics: Calcium; Calpain; Cell Line; Cellular Senescence; Diploidy; Endopeptidases; Fibroblasts; Humans; Osmolar Concentration; Protein Kinase C; Protein Kinases; Serine; Threonine | 1993 |
Phosphorylation of connexin-32 by protein kinase C prevents its proteolysis by mu-calpain and m-calpain.
Topics: Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Calmodulin; Calpain; Cell Membrane; Connexins; Erythrocytes; Humans; Isoenzymes; Liver; Male; Membrane Proteins; Mice; Molecular Sequence Data; Muscles; Phosphorylation; Protein Kinase C; Protein Kinases; Rabbits; Rats; Rats, Sprague-Dawley; Serine | 1993 |
Muscle-specific calpain, p94, is degraded by autolysis immediately after translation, resulting in disappearance from muscle.
Topics: Amino Acid Sequence; Animals; Base Sequence; Calpain; Cell Line; Chlorocebus aethiops; Cysteine; Immunohistochemistry; Kidney; Macromolecular Substances; Molecular Sequence Data; Molecular Weight; Muscles; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Protein Biosynthesis; Rats; Recombinant Proteins; RNA, Messenger; Sequence Deletion; Serine; Transfection | 1993 |
Functional cleavage of the common cytokine receptor gamma chain (gammac) by calpain.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Calpain; CD4-Positive T-Lymphocytes; Cells, Cultured; DNA Primers; Glutamic Acid; Humans; Interleukin-2; Ionomycin; Lymphocyte Activation; Macromolecular Substances; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Proline; Protein Biosynthesis; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Cytokine; Recombinant Proteins; Sequence Alignment; Serine; Signal Transduction; Substrate Specificity; T-Lymphocytes; Threonine | 1997 |
m-Calpain subunits remain associated in the presence of calcium.
Topics: Alanine; Animals; Calcium; Calpain; Caseins; Catalytic Domain; Cattle; Cysteine; Dimerization; Glutamic Acid; Kinetics; Macromolecular Substances; Mutagenesis, Site-Directed; Protein Binding; Recombinant Proteins; Serine | 1998 |
Inhibition of mutant p53 phosphorylation at serine 15 or serine 315 partially restores the function of wild-type p53.
Topics: Apoptosis; Base Sequence; Binding Sites; Calpain; Cell Division; Cell Line; Cyclin-Dependent Kinases; DNA; DNA Primers; DNA-Activated Protein Kinase; DNA-Binding Proteins; Humans; Nuclear Proteins; Phosphorylation; Point Mutation; Protein Serine-Threonine Kinases; Serine; Transfection; Tumor Suppressor Protein p53 | 1999 |
Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress.
Topics: Animals; Calpain; Casein Kinase II; Cysteine Endopeptidases; DNA; DNA-Binding Proteins; Enzyme Activation; Humans; Hydrogen Peroxide; I-kappa B Kinase; I-kappa B Proteins; Mice; Multienzyme Complexes; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidative Stress; Peptide Fragments; Phosphorylation; Point Mutation; Proteasome Endopeptidase Complex; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Tyrosine Phosphatase, Non-Receptor Type 12; Protein Tyrosine Phosphatases; Serine; Tumor Cells, Cultured; Tyrosine | 2000 |
Determination of a cAMP-dependent protein kinase phosphorylation site in the C-terminal region of human endothelial actin-binding protein.
Topics: Amino Acid Motifs; Amino Acid Substitution; Blood Platelets; Calpain; Contractile Proteins; Cyclic AMP-Dependent Protein Kinases; Endothelium; Filamins; Humans; Immune Sera; Microfilament Proteins; Molecular Weight; Mutation; Peptide Fragments; Phosphorylation; Phosphoserine; Recombinant Proteins; Sequence Analysis, Protein; Serine; Threonine | 2000 |
Myopathy phenotype of transgenic mice expressing active site-mutated inactive p94 skeletal muscle-specific calpain, the gene product responsible for limb girdle muscular dystrophy type 2A.
Topics: Animals; Binding Sites; Body Weight; Calpain; Connectin; Cysteine; Female; Immunohistochemistry; Mice; Mice, Transgenic; Muscle Proteins; Muscle, Skeletal; Muscular Diseases; Muscular Dystrophies; Mutation; Phenotype; Plasmids; Polymerase Chain Reaction; Protein Kinases; Serine | 2000 |
Role of calpain in hypoxic inhibition of nitric oxide synthase activity in pulmonary endothelial cells.
Topics: Animals; Calpain; Caveolin 1; Caveolins; Cells, Cultured; Cysteine Proteinase Inhibitors; Dipeptides; Endothelium, Vascular; HSP90 Heat-Shock Proteins; Hypoxia; Membrane Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Pulmonary Artery; Serine; Swine; Tyrosine | 2000 |
Calpain mutants with increased Ca2+ sensitivity and implications for the role of the C(2)-like domain.
Topics: Animals; Calcium; Calpain; Crystallography, X-Ray; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Point Mutation; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Salts; Serine | 2001 |
Oxidative stress induces neuronal death by recruiting a protease and phosphatase-gated mechanism.
Topics: Animals; Apoptosis; Calcineurin; Calcium-Calmodulin-Dependent Protein Kinases; Calpain; Caspases; Cyclic AMP Response Element-Binding Protein; Hydrogen Peroxide; Mice; Necrosis; Neurons; Oxidative Stress; Phosphoprotein Phosphatases; Phosphorylation; Protein Biosynthesis; Serine | 2001 |
DNA ligase III is degraded by calpain during cell death induced by DNA-damaging agents.
Topics: Amino Acid Motifs; Amino Acid Substitution; Apoptosis; Aspartic Acid; Calpain; DNA Damage; DNA Ligase ATP; DNA Ligases; Humans; Mutagenesis, Site-Directed; Poly-ADP-Ribose Binding Proteins; Proline; Recombinant Proteins; Serine; Threonine; Transfection; Tumor Cells, Cultured; Two-Hybrid System Techniques; Xenopus Proteins | 2002 |
A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.
Topics: Amino Acid Sequence; Animals; Apolipoprotein A-I; Arteriosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Biological Transport; Calpain; Cell Line; Cell Membrane; Cells, Cultured; Chickens; Cholesterol; Cross-Linking Reagents; Dipeptides; DNA; Dose-Response Relationship, Drug; Endopeptidases; Glutamic Acid; Hepatocytes; Humans; Ligands; Lipid Metabolism; Macrophages; Mice; Molecular Sequence Data; Phospholipids; Plasmids; Proline; Serine; Threonine; Time Factors; Transfection; Up-Regulation | 2003 |
Glutamate substitutions at a PKA consensus site are consistent with inactivation of calpain by phosphorylation.
Topics: Amino Acid Substitution; Animals; Calcium; Calpain; Consensus Sequence; Cyclic AMP-Dependent Protein Kinases; Enzyme Stability; Glutamic Acid; Mutation; Phosphorylation; Rats; Serine; Threonine | 2003 |
Epidermal growth factor activates m-calpain (calpain II), at least in part, by extracellular signal-regulated kinase-mediated phosphorylation.
Topics: Amino Acid Substitution; Animals; Base Sequence; Binding Sites; Calcium; Calpain; Cell Line; Cell Movement; DNA, Complementary; Enzyme Activation; Epidermal Growth Factor; Humans; In Vitro Techniques; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Phosphorylation; Recombinant Proteins; Serine | 2004 |
Dual inhibition of protein phosphatase-1/2A and calpain rescues nerve growth factor-differentiated PC12 cells from oxygen-glucose deprivation-induced cell death.
Topics: Animals; Blotting, Western; Calpain; Cell Differentiation; CREB-Binding Protein; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glucose; Hypoxia; L-Lactate Dehydrogenase; Nerve Growth Factor; Neural Inhibition; Neurons; Oncogene Protein v-akt; Oxygen; PC12 Cells; Phosphoprotein Phosphatases; Protein Phosphatase 1; Rats; Serine; Spectrin; tau Proteins; Threonine; Time Factors | 2006 |
Calcineurin dephosphorylates the C-terminal region of filamin in an important regulatory site: a possible mechanism for filamin mobilization and cell signaling.
Topics: Actins; Animals; Blood Platelets; Calcineurin; Calcineurin Inhibitors; Calpain; Cell Line; Cell Membrane; Contractile Proteins; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; Filamins; Humans; Mice; Microfilament Proteins; Mutagenesis; Phosphorylation; Protein Structure, Tertiary; Recombinant Proteins; Serine; Signal Transduction | 2006 |
Calpain-resistant fragment(s) of alpha-synuclein regulates the synuclein-cleaving activity of 20S proteasome.
Topics: alpha-Synuclein; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Calpain; Electrophoresis, Polyacrylamide Gel; Glutamates; Hydrolysis; Models, Biological; Molecular Sequence Data; Mutation; Proline; Proteasome Endopeptidase Complex; Serine; Substrate Specificity; Swine; Threonine | 2006 |
M-calpain-mediated cleavage of GAP-43 near Ser41 is negatively regulated by protein kinase C, calmodulin and calpain-inhibiting fragment GAP-43-3.
Topics: Amino Acid Sequence; Animals; Calmodulin; Calpain; Cattle; GAP-43 Protein; Models, Biological; Peptide Fragments; Protein Kinase C; Rats; Serine; Synaptosomes | 2007 |
p53 stabilization can be uncoupled from its role in transcriptional activation by loss of PTTG1/securin.
Topics: Amino Acid Sequence; Calpain; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Humans; Neoplasm Proteins; Protein Processing, Post-Translational; Securin; Serine; Transcriptional Activation; Tumor Suppressor Protein p53; Ubiquitin | 2007 |
Truncation of human dopamine transporter by protease calpain.
Topics: Amino Acid Sequence; Animals; Calpain; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Female; Humans; Peptide Fragments; Protein Kinase C; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Receptors for Activated C Kinase; Receptors, Cell Surface; Receptors, Dopamine D2; Recombinant Proteins; Serine; Synaptosomes; Threonine | 2008 |
Smurf1 zaps the talin head.
Topics: Animals; Calpain; Cell Movement; Cyclin-Dependent Kinase 5; Focal Adhesions; Mice; Models, Biological; Phosphorylation; Proteasome Endopeptidase Complex; Protein Interaction Domains and Motifs; Pseudopodia; Serine; Talin; Ubiquitin-Protein Ligases; Ubiquitination | 2009 |
Cytosolic Aryl sulfotransferase 4A1 interacts with the peptidyl prolyl cis-trans isomerase Pin1.
Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Calpain; Cysteine Proteinase Inhibitors; Cytosol; Escherichia coli; Escherichia coli Proteins; Glutathione Transferase; Half-Life; HeLa Cells; Humans; Leupeptins; Molecular Sequence Data; NIMA-Interacting Peptidylprolyl Isomerase; Okadaic Acid; Peptidylprolyl Isomerase; Phosphorylation; Proline; Protein Binding; Recombinant Proteins; Serine; Sulfotransferases; Threonine; Transfection; Two-Hybrid System Techniques | 2009 |
Site-specific phosphorylation protects glycogen synthase kinase-3β from calpain-mediated truncation of its N and C termini.
Topics: Animals; Apoptosis; Calpain; Cerebellum; Glutamine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Humans; Isoleucine; Mutagenesis; Nerve Degeneration; Neurons; Phosphorylation; Protein Structure, Tertiary; Rabbits; Rats; Serine; Threonine | 2012 |
Cleavage of GSK-3β by calpain counteracts the inhibitory effect of Ser9 phosphorylation on GSK-3β activity induced by H₂O₂.
Topics: Calcium; Calpain; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Glycoproteins; HEK293 Cells; Humans; Hydrogen Peroxide; Intracellular Fluid; Malondialdehyde; Mutation; Oncogene Protein v-akt; Oxidative Stress; Phosphorylation; Serine; Signal Transduction; Superoxide Dismutase; tau Proteins; Transfection; Up-Regulation | 2013 |
Muscle-specific calpain-3 is phosphorylated in its unique insertion region for enrichment in a myofibril fraction.
Topics: Adolescent; Animals; Calpain; Chlorocebus aethiops; COS Cells; Female; Humans; Male; Middle Aged; Muscle Proteins; Muscle, Skeletal; Muscular Dystrophies, Limb-Girdle; Mutagenesis, Insertional; Mutation; Myofibrils; Phosphorylation; Serine; Signal Transduction; Young Adult | 2014 |
Accumulation of α-synuclein in dementia with Lewy bodies is associated with decline in the α-synuclein-degrading enzymes kallikrein-6 and calpain-1.
Topics: alpha-Synuclein; Alzheimer Disease; Brain; Calpain; Case-Control Studies; Cell Line, Tumor; Child; Child, Preschool; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation; Humans; Kallikreins; Lewy Body Disease; Male; Neuroblastoma; Phosphorylation; RNA, Small Interfering; Serine | 2014 |
A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis.
Topics: Actins; Calcium; Calpain; Humans; Myocytes, Cardiac; Myofibrils; Phosphorylation; Protein Binding; Protein Interaction Domains and Motifs; Proteolysis; Sarcomeres; Serine; Troponin I | 2015 |
Heart Failure-Related Hyperphosphorylation in the Cardiac Troponin I C Terminus Has Divergent Effects on Cardiac Function In Vivo.
Topics: Adrenergic beta-Agonists; Animals; Calpain; Disease Models, Animal; Genetic Predisposition to Disease; Heart Failure; Hemodynamics; Isolated Heart Preparation; Male; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Myocardial Contraction; Myocardial Reperfusion Injury; Myofibrils; Myosin Heavy Chains; Phenotype; Phosphorylation; Promoter Regions, Genetic; Protein Domains; Protein Stability; Proteolysis; Recovery of Function; Serine; Time Factors; Troponin I; Ventricular Function, Left | 2017 |
TET2 stabilization by 14-3-3 binding to the phosphorylated Serine 99 is deregulated by mutations in cancer.
Topics: 14-3-3 Proteins; Calpain; Cell Line; Dioxygenases; DNA-Binding Proteins; HEK293 Cells; Humans; Mutation; Neoplasms; Phosphorylation; Protein Domains; Proto-Oncogene Proteins; Serine | 2019 |
Phosphorylation of Serine 157 Protects the Rat Glycine Transporter GlyT2 from Calpain Cleavage.
Topics: Amino Acid Motifs; Animals; Calpain; Cell Line, Tumor; Glycine Plasma Membrane Transport Proteins; Mice; Mutation, Missense; Phosphorylation; Protein Processing, Post-Translational; Proteolysis; Rats; Serine | 2020 |