serine and aspirin

serine has been researched along with aspirin in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.09)18.7374
1990's7 (31.82)18.2507
2000's8 (36.36)29.6817
2010's3 (13.64)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Roth, GJ; Siok, CJ1
DeWitt, DL; Shimokawa, T; Smith, WL1
Andrews, MJ; Armstrong, RL; DeWitt, DL; el-Harith, EA; Kraemer, SA; Smith, WL; Yao, EF1
DeWitt, DL; Kraemer, SA; Meade, EA; Shimokawa, T; Smith, WL1
Kennedy, A; Saluga, PG1
Garavito, RM; Loll, PJ; Picot, D1
Allentoff, A; Bowen, BR; Boyer, W; Kelly, M; Liang, H; Marshall, P; Miller, DB; Quintavalla, JC; Wasvary, J; Wennogle, LP1
Allen, KN1
Bayly, C; Mancini, JA; O'Neill, GP; Vickers, PJ1
Dedhar, S; Dupuis, B; Gallinger, S; Gray, V; Malik, S; Marotta, A; Owen, D; Salh, B; Sanghera, J; Tan, C1
Hori, H; Kawahara, J; Kobayashi, M1
Dong, Z; Gao, Z; Quon, MJ; Ye, J; Zuberi, A1
Barreiro, GC; Caliseo, CT; Carvalheira, JB; Fugiwara, FY; Prada, PO; Prattali, RR; Saad, MJ; Ueno, M; Velloso, LA1
Avila, J; Pérez, M; Tortosa, E1
Lazzarato, L; Tosco, P1
Ferro, A; Jackson, G; Ji, Y; Liu, Z; O'Kane, P; Queen, L; Xie, L1
Adamo, MF; Alagha, A; Chubb, AJ; Moman, E; Nolan, KB1
Kim, MJ; Rangasamy, S; Shim, Y; Song, JM1
Ameen, M; Fenner, BJ; Kinsella, S; König, HG; Prehn, JHM; Watters, O1
Finamore, F; Fontana, P; Malacarne, S; Reny, JL; Sanchez, JC1
Ballerini, P; Bruno, A; Contursi, A; D'Agostino, I; Dovizio, M; Falcone, L; Fullone, R; Mucci, M; Patrignani, P; Sacco, A; Tacconelli, S; Zucchelli, M1
Cai, XR; Chi, YN; Huang, RQ; Miao, XY; Wang, CF; Xiao, BK; Yang, JY1

Reviews

2 review(s) available for serine and aspirin

ArticleYear
Aspirin--now we can see it.
    Nature medicine, 1995, Volume: 1, Issue:9

    Topics: Acetylation; Animals; Arachidonic Acid; Aspirin; Binding Sites; Computer Simulation; Cyclooxygenase Inhibitors; Flurbiprofen; Isoenzymes; Models, Molecular; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins H; Protein Binding; Serine; Sheep

1995
[Development of new antidiabetic drugs through the advanced knowledge of molecular biology in insulin signal transduction].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 9

    Topics: Animals; Aspirin; Drug Design; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Tyrosine Phosphatases; Receptor, Insulin; Serine; Signal Transduction; Threonine; Tumor Necrosis Factor-alpha

2002

Trials

1 trial(s) available for serine and aspirin

ArticleYear
A high glucose level is associated with decreased aspirin-mediated acetylation of platelet cyclooxygenase (COX)-1 at serine 529: A pilot study.
    Journal of proteomics, 2019, 02-10, Volume: 192

    Topics: Acetylation; Adult; Aspirin; Blood Glucose; Blood Platelets; Cyclooxygenase 1; Diabetes Mellitus; Female; Humans; Male; Pilot Projects; Serine

2019

Other Studies

19 other study(ies) available for serine and aspirin

ArticleYear
Acetylation of the NH2-terminal serine of prostaglandin synthetase by aspirin.
    The Journal of biological chemistry, 1978, Jun-10, Volume: 253, Issue:11

    Topics: Acetylation; Animals; Aspirin; Cattle; Cyclooxygenase Inhibitors; Male; Peptide Fragments; Seminal Vesicles; Serine; Sheep

1978
The aspirin and heme binding sites of PGG/H synthase.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: Amino Acid Sequence; Animals; Aspirin; Binding Sites; Cyclooxygenase Inhibitors; Heme; Histidine; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Prostaglandin-Endoperoxide Synthases; Sequence Homology, Nucleic Acid; Serine; Sheep; Species Specificity

1991
The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxide synthases.
    The Journal of biological chemistry, 1990, Mar-25, Volume: 265, Issue:9

    Topics: Amino Acid Sequence; Animals; Aspirin; Base Sequence; Binding Sites; Blotting, Western; DNA; Genetic Vectors; Heme; Mice; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Prostaglandin-Endoperoxide Synthases; Restriction Mapping; Sequence Homology, Nucleic Acid; Serine; Sheep

1990
Molecular basis for the inhibition of prostanoid biosynthesis by nonsteroidal anti-inflammatory agents.
    Stroke, 1990, Volume: 21, Issue:12 Suppl

    Topics: Acetylation; Alanine; Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; DNA; DNA Restriction Enzymes; Exons; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Hybridization; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Serine; Sheep

1990
Urinary cytology in experimental toxic renal injury.
    Annals of the rheumatic diseases, 1970, Volume: 29, Issue:5

    Topics: Acute Kidney Injury; Animals; Aspirin; Azirines; Chromates; Eosinophils; Histocytochemistry; Kidney Diseases; Kidney Tubules; Male; Mercury Poisoning; Quaternary Ammonium Compounds; Rats; Serine; Uranium; Urine

1970
The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase.
    Nature structural biology, 1995, Volume: 2, Issue:8

    Topics: Acetylation; Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Crystallography, X-Ray; Cyclooxygenase Inhibitors; Isoenzymes; Kinetics; Models, Molecular; Molecular Conformation; Prostaglandin-Endoperoxide Synthases; Protein Conformation; Protein Structure, Secondary; Serine; Sheep

1995
Comparison of recombinant cyclooxygenase-2 to native isoforms: aspirin labeling of the active site.
    FEBS letters, 1995, Sep-11, Volume: 371, Issue:3

    Topics: Amino Acid Sequence; Amino Acids; Animals; Aspirin; Binding Sites; Cattle; Gene Expression Regulation, Enzymologic; Glycosylation; Humans; Kinetics; Molecular Sequence Data; Peptide Mapping; Prostaglandin-Endoperoxide Synthases; Recombinant Fusion Proteins; Serine

1995
Mutation of serine-516 in human prostaglandin G/H synthase-2 to methionine or aspirin acetylation of this residue stimulates 15-R-HETE synthesis.
    FEBS letters, 1994, Mar-28, Volume: 342, Issue:1

    Topics: Acetylation; Animals; Aspirin; Cell Line; Humans; Hydroxyeicosatetraenoic Acids; Methionine; Microsomes; Mutagenesis, Site-Directed; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Serine

1994
Dysregulation of integrin-linked kinase (ILK) signaling in colonic polyposis.
    Oncogene, 2001, Sep-27, Volume: 20, Issue:43

    Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Polyps; Disease Progression; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation, Enzymologic; Humans; Mutation; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Signal Transduction; Sulindac; Time Factors; Tumor Cells, Cultured

2001
Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in tumor necrosis factor-treated cells through targeting multiple serine kinases.
    The Journal of biological chemistry, 2003, Jul-04, Volume: 278, Issue:27

    Topics: 3T3 Cells; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Signal Transduction; Tumor Necrosis Factor-alpha

2003
Aspirin inhibits serine phosphorylation of IRS-1 in muscle and adipose tissue of septic rats.
    Biochemical and biophysical research communications, 2004, Jul-30, Volume: 320, Issue:3

    Topics: Adipose Tissue; Animals; Aspirin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Muscle, Skeletal; Phosphoproteins; Phosphorylation; Rats; Rats, Wistar; Sepsis; Serine

2004
Acetylsalicylic acid decreases tau phosphorylation at serine 422.
    Neuroscience letters, 2006, Mar-20, Volume: 396, Issue:1

    Topics: Alzheimer Disease; Amino Acid Sequence; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain; Cell Line, Tumor; Down-Regulation; Humans; Neurons; Phosphorylation; Serine; tau Proteins

2006
Mechanistic insights into cyclooxygenase irreversible inactivation by aspirin.
    ChemMedChem, 2009, Volume: 4, Issue:6

    Topics: Acetylation; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Catalysis; Catalytic Domain; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Models, Chemical; Prostaglandin-Endoperoxide Synthases; Serine; Structure-Activity Relationship

2009
Aspirin acetylates nitric oxide synthase type 3 in platelets thereby increasing its activity.
    Cardiovascular research, 2009, Jul-01, Volume: 83, Issue:1

    Topics: Acetylation; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; HeLa Cells; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Serine; Transfection; Young Adult

2009
Design, synthesis and evaluation of aspirin analogues having an additional carboxylate substituent for antithrombotic activity.
    Bioorganic & medicinal chemistry letters, 2009, Aug-01, Volume: 19, Issue:15

    Topics: Arginine; Aspirin; Carboxylic Acids; Catalytic Domain; Chemistry, Pharmaceutical; Drug Design; Esters; Humans; Platelet Activation; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Serine; Thrombosis; Tyrosine

2009
Cell lysis-free quantum dot multicolor cellular imaging-based mechanism study for TNF-α-induced insulin resistance.
    Journal of nanobiotechnology, 2015, Jan-27, Volume: 13

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Aspirin; Cinnamates; Forkhead Box Protein O1; Forkhead Transcription Factors; Glucose; Glycogen; Hep G2 Cells; Humans; Indomethacin; Inflammation; Insulin Receptor Substrate Proteins; Insulin Resistance; Molecular Imaging; Molecular Targeted Therapy; Protein Kinases; Quantum Dots; Reproducibility of Results; Serine; Tumor Necrosis Factor-alpha

2015
A constitutively-active IKK-complex at the axon initial segment.
    Brain research, 2018, Jan-01, Volume: 1678

    Topics: Animals; Ankyrins; Aspirin; Axon Initial Segment; Calbindins; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Flow Cytometry; Green Fluorescent Proteins; I-kappa B Kinase; I-kappa B Proteins; Ligation; Mice; Mice, Inbred C57BL; Neurons; Phosphorylation; Rats; RNA, Small Interfering; Serine; Signal Transduction; Time Factors; Transfection

2018
Characterization of cyclooxygenase-2 acetylation and prostanoid inhibition by aspirin in cellular systems.
    Biochemical pharmacology, 2020, Volume: 178

    Topics: Acetylation; Amino Acid Sequence; Arachidonic Acid; Aspirin; Cell Line, Tumor; Chromatography, Liquid; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Epithelial Cells; Gene Expression; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-1beta; Lipopolysaccharides; Mass Spectrometry; Monocytes; Primary Cell Culture; Protein Processing, Post-Translational; Recombinant Proteins; Serine

2020
Analgesic Activity of Jin Ling Zi Powder and Its Single Herbs: A Serum Metabonomics Study.
    Chinese journal of integrative medicine, 2022, Volume: 28, Issue:11

    Topics: Analgesics; Animals; Aspirin; Biomarkers; Body Weight; Drugs, Chinese Herbal; Glycine; Glyoxylates; Inositol Phosphates; Isoleucine; Leucine; Metabolomics; Mice; Powders; RNA, Transfer; Serine; Threonine; Valine

2022