serine has been researched along with asparagine in 502 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 151 (30.08) | 18.7374 |
| 1990's | 130 (25.90) | 18.2507 |
| 2000's | 149 (29.68) | 29.6817 |
| 2010's | 62 (12.35) | 24.3611 |
| 2020's | 10 (1.99) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Hara, TJ | 1 |
| Colosi, NW; Harper, AE; Tews, JK | 1 |
| Bachrach, HL; Matheka, HD | 1 |
| Benuck, M; Lajtha, A | 1 |
| Marshall, RD | 2 |
| Efremov, GD; Huisman, TH; Lam, HL; Stojmirovic, E; Wilson, JB | 1 |
| Mauk, MR; Putz, GR; Taketa, F | 1 |
| Barbeau, A; Beroniade, V; Breton, G; Geoffroy, G; Lemieux, B; Melançon, S; Shapcott, D | 1 |
| Barker, JL; Nicoll, RA; Padjen, A | 1 |
| Dolowy, WC; Holcenberg, JS; Tang, E | 1 |
| Black, JA; Harkins, RN; Stenzel, P | 1 |
| Rando, RR | 1 |
| Chellemi, F | 1 |
| Gundalakh, AI; Mel'k, MV; Shcheglova, SA; Volkova, ZA | 1 |
| Jaenicke, R; Risse, B; Rudolph, R; Schumacher, G; Stempfer, G | 1 |
| Beg, OU; Brewer, HB; Brunzell, JD; Emmerich, J; Peterson, J; Previato, L; Santamarina-Fojo, S | 1 |
| Carlson, H; Hillered, L; Ronne-Engström, E; Ungerstedt, U | 1 |
| Asahara, H; Hasegawa, T; Himeno, H; Shimizu, M; Tamura, K | 1 |
| Fukamachi, I; Hashimoto, H; Kobayashi, J; Morimoto, Y; Nishida, T; Saito, Y; Shibui, T; Shirai, K; Tashiro, J; Yoshida, S | 1 |
| Day, R; Farnsworth, CL; Feig, LA; Hildebrandt, JD | 1 |
| Chan, WY; Hill, PS; Hruby, VJ | 1 |
| Arocha-Piñango, CL; Carvajal, Z; de Bosch, NB; Hirata, H; Kaneko, M; Maekawa, H; Muramatsu, S; Ojeda, A; Takahashi, N; Yamazumi, K | 1 |
| Hollosi, M; Kollat, E; Mantsch, HH; Otvos, L; Thurin, J; Urge, L | 1 |
| Baumann, M; Kauppinen-Mäkelin, R; Kontula, K; Koskinen, P; Lukka, M; Manninen, V; Mänttäri, M; Metso, J; Taskinen, MR; Tenkanen, H | 1 |
| Cummings, RD; Kuwano, M; Merkle, RK; Ono, M; Seguchi, T | 1 |
| Cartron, JP; Colin, Y; Guizzo, ML; Le Van Kim, C; Telen, MJ | 1 |
| Brown, DM; Friedman, AR; Guido, DM; Hillman, RM; Ichhpurani, AK; Krabill, LF; Martin, RA; Zurcher-Neely, HA | 1 |
| Barbato, G; Bax, A; Ikura, M; Kay, LE; Krinks, M; Spera, S | 1 |
| Shulman, MJ; Sun, WY; Xiong, J | 1 |
| Isenman, DE; Painter, RH; Shulman, MJ; Wright, JF | 1 |
| Avanov, AIa; Lipkind, GM | 1 |
| Brayer, GD; Funk, WD; Lo, TP; MacGillivray, RT; Mauk, AG; Mauk, MR | 1 |
| Dusart, J; Frère, JM; Jacob, F; Joris, B; Lepage, S | 1 |
| Cox, GB; Gibson, F; Howitt, SM | 1 |
| Abumurad, N; Ghishan, FK; Nylander, W; Redha, R; Said, HM; Van Voorhis, K | 1 |
| Abumrad, NN; Ghishan, FK; Said, HM; Van Voorhis, K | 1 |
| Imai, Y; Nakamura, M | 1 |
| Carroll, RD; Haffey, ML; Matthews, JT; Stevens, JT | 1 |
| Daly, MP; Demediuk, P; Faden, AI | 1 |
| Craik, CS; Finer-Moore, J; Fletterick, RJ; Hamlin, R; Rutter, WJ; Sprang, S; Standing, T; Stroud, RM; Xuong, NH | 1 |
| Kopple, JD; Wolfson, M | 1 |
| Crechet, JB; De Vendittis, E; Fasano, O; Feger, G; Parmeggiani, A; Vitelli, A; Zahn, R | 1 |
| Cooper, GM; Feig, LA | 1 |
| Kantrowitz, ER; Middleton, SA | 1 |
| Koerner, T; Olson, C; Rodén, L; Schwartz, NB | 1 |
| Keefer, JF; Moraga, DA; Schuster, SM | 1 |
| Gruber, C; Levine, S | 1 |
| Imamura, S | 1 |
| Garg, HG; Jeanloz, RW | 1 |
| Mircevová, L; Mokrý, Z; Simonová, A | 1 |
| Jaton, JC | 1 |
| Pliskowá, M | 1 |
| Veerkamp, JH | 1 |
| Atherton, DM; Margolis, RK; Margolis, RU | 1 |
| Erler, W; Feist, H; Flossmann, KD; Höfer, M | 2 |
| Abrol, YP; Blumenthal, SG; Conn, EE; Hendrickson, HR | 1 |
| DeBernardo, SL; Jamieson, GA; Jett, M | 1 |
| Asano, Y; Fukui, A; Sinoara, H | 1 |
| Derevitskaya, VA; Kochetkov, NK; Likhosherstov, LM; Medvedev, SA | 1 |
| Hogan, BL; Murden, S | 1 |
| Crippa, PR; Tedeschi, RA; Vecli, A | 1 |
| Höcker, P; Stacher, A; Weiser, M | 1 |
| Iversen, LL; Snodgrass, SR | 1 |
| Peterkofsky, A; Powers, DM | 1 |
| Bossinger, J; Cooper, TG; Lawther, RP | 1 |
| Halpern, YS | 1 |
| Pittsyn, OB | 1 |
| Boyer, ML; Boyer, SH; Marr, K; Noyes, AN | 1 |
| Anderson, PJ; Gibson, D | 1 |
| Ali, A; Faesel, JH; Sarantakis, D; Stevenson, D; Weinstein, B | 1 |
| Alimov, IIu; Iur'eva, EA; Marchenko, ZM | 1 |
| Harper, AE; Maruyama, K; Sunde, ML | 1 |
| Büchner, M; Hofmann, F; Scheid, P | 1 |
| Bentyn, K; Choroszewska, A; Jaszczak, S | 1 |
| Betz, AL; Gilboe, DD | 1 |
| Adibi, SA; Amin, PM; Modesto, TA; Morse, EL | 1 |
| Gurd, FR; Keim, P; Marshall, RC; Morrow, JS; Vigna, RA | 1 |
| Manchester, KL; Turner, LV | 1 |
| Arkhipova, SF; Lipkind, GM; Popov, EM | 1 |
| Maruyama, T; Sinohara, H | 1 |
| Bergström, J; Fürst, P; Norée, LO; Vinnars, E | 1 |
| Blouquit, Y; Cohen-Solal, M; Garel, MC; Rosa, J | 1 |
| Doores, L; Schulman, JD; Silagi, S; Wrathall, JR | 1 |
| Anandaraj, MP; Cherayil, JD | 1 |
| Kalnitsky, G; Spadari, S; Subramanian, AR | 1 |
| Berger, H; Yanofsky, C | 1 |
| Spiro, RG | 1 |
| Kishida, Y; Sakakibara, S | 1 |
| Hardman, JK; Myers, JS | 1 |
| Jenkins, WT; Martinez-Carrion, M | 1 |
| Kinoshita, Y; Nemoto, G; Ujiie, A | 1 |
| Castric, PA; Strobel, GA | 1 |
| Tanaka, Y | 1 |
| Coan, MH; Roberts, RC; Travis, J | 1 |
| Arima, T; Spiro, MJ; Spiro, RG | 1 |
| Hafez, ES; Jaszczak, S; Kurrie, DA; Moghissi, KS | 1 |
| Alden, RA; Kraut, J; Wright, CS | 1 |
| Husain, I; Norris, RF; Poupard, JA | 1 |
| Fujita, S | 1 |
| Asmar, JA; Daghir, NJ; Sifri, M | 1 |
| Christensen, HN; Koser, BH | 1 |
| Kotelchuck, D; Scheraga, HA | 1 |
| Faulcon, FM; Lee, WH; Regan, JD; Takeda, S; Vodopick, N | 1 |
| Cieślak, M; Krzemiński, Z | 1 |
| Jones, OW; Nirenberg, MW | 1 |
| Nunn, PB; Vega, A | 1 |
| Schubert, RH | 1 |
| Chen, DM; Harper, AE; Rogers, QR | 1 |
| Nicholson, I | 1 |
| Lohrenz, FN; Tewksbury, DA | 1 |
| Galizzi, A | 1 |
| Dayhoff, MO; Hunt, LT | 1 |
| Melcher, G | 1 |
| Baranova, IP; Egorov, NS | 1 |
| Golovach, VM; Ratich, IB | 1 |
| Delaunay, J; Maleknia, N; Schapira, G | 1 |
| Forest, JC; Wightman, F | 1 |
| Kloss, G; Schwarz, E | 1 |
| Demeyer, DI; Henderickx, HK | 1 |
| Ishihara, H; Sasaki, T; Shimura, K | 1 |
| McConnell, WB; Nigam, SN | 1 |
| Bodnaryk, RP; Levenbook, L | 1 |
| Schneider, G | 1 |
| Dietel, K; Schmöger, R | 1 |
| Hertel, W; Rohrlich, M | 1 |
| Chaudhury, RR; Datta, H | 1 |
| Schwartz, AC | 1 |
| Hanson, H; Kettmann, U; Kretschmer, K | 1 |
| Brysk, MM; Corpe, WA; Hankes, LV | 1 |
| Lampen, JO; Neumann, NP | 1 |
| Christian, JH; Waltho, JA | 1 |
| Hentschel, G; Kull, U | 1 |
| Andreeva, LA | 1 |
| Grooten, HJ; van der Horst, CJ | 1 |
| Francis, FJ; Fuleki, T | 1 |
| Alburn, HE; Grant, NH | 1 |
| Jones, HE; Park, RW | 1 |
| Kuttner, RE; Lorincz, AB; Portoghese, A | 1 |
| Carlisle, SA; Morse, GE; Willett, NP | 1 |
| Agnihotri, VP; Vaartaja, O | 1 |
| Brockhausen, I; Gleeson, P; Narasimhan, S; Schachter, H; Vella, GJ | 1 |
| Haselbeck, A; Lehle, L; Schwaiger, H; Tanner, W | 1 |
| Stanley, P | 1 |
| Bahl, OP; Wagh, PV | 1 |
| Ireland, RJ; Joy, KW | 1 |
| Lennarz, WJ; Naider, F; Shenbagamurthi, P; Welply, JK | 1 |
| Bause, E | 1 |
| Aubert, JP; Helbecque, N; Loucheux-Lefebvre, MH | 1 |
| Arnone, A; Rosa, J; Thillet, J | 1 |
| Wold, F | 1 |
| Dion, AS; Farwell, DC | 1 |
| de Gasparo, M; Milner, RD | 1 |
| Aubert, JP; Ronin, C | 1 |
| Foley, BT; Moehring, JM; Moehring, TJ | 1 |
| Aendekerk, J; Bloemendal, H; De Jong, WW; Horwitz, J; Merck, KB; Slingsby, C; Smulders, RH; Takemoto, L | 1 |
| Bock, SC; Ersdal-Badju, E; Picard, V | 1 |
| Boudon, C; Garandeau, P; Lobaccaro, JM; Lumbroso, S; Montoya, P; Romer, TE; Sultan, C; Szarras-Czapnik, M | 1 |
| Bian, ZC; Oswald, RE; Wo, ZG | 1 |
| Bálint, M; Gráf, L; Kaslik, G; Patthy, A | 1 |
| Bütler, R; Heliö, T; Huttunen, JK; Ilmonen, M; Palotie, A; Pietinen, P; Tikkanen, MJ | 1 |
| de Kok, A; Hendle, J; Hol, WG; Mattevi, A; Spee, J; Teplyakov, A; Westphal, AH | 1 |
| Kivirikko, KI; Lamberg, A; Pihlajaniemi, T | 1 |
| Harrison, RW; Pilkis, SJ; Weber, IT; Xu, LZ | 1 |
| Cusick, ME | 1 |
| Burgeson, RE; Gerecke, DR; Mayer, U; Pöschl, E; Timpl, R; Wagman, DW | 1 |
| Kaplan, JB | 1 |
| Offer, G; Sessions, R | 1 |
| Takahashi, K; Takeuchi, Y | 1 |
| Cama, A; Dreyer, M; Kadowaki, H; Kadowaki, T; Quon, MJ; Rüdiger, HW; Sierra, ML; Taylor, SI | 1 |
| Cornish, VW; Kaplan, MI; Kollman, PA; Schultz, PG; Veenstra, DL | 1 |
| Garg, HG; Kunz, H; von dem Bruch, K | 1 |
| Kodama, H; Sugahara, K; Zhang, J | 1 |
| Arrandale, JM; Dannies, PS | 1 |
| Brewer, HB; Fojo, SS; Fujita, Y; Inadera, H; Kobayashi, J; Morisaki, N; Saito, Y; Talley, G; Yoshida, S | 1 |
| Brenner, B; Clemetson, JM; Clemetson, KJ; Kyrle, PA | 1 |
| Fedele, E; Foster, AC | 1 |
| Alliey, N; Berthon, G; Brumas, V | 1 |
| Borsellino, G; Colonna, M; Falco, M; Ferrara, GB; Strominger, JL | 1 |
| Chen, MX; Chen, YH; Cohen, PT | 1 |
| Procyshyn, RM; Reid, RE | 1 |
| Geyer, R; Pfeiffer, G; Schmidt, M; Strube, KH | 1 |
| Frère, JM; Jamin, M; Wilkin, JM | 1 |
| Aerts, JM; Barranger, JA; Sa Miranda, MC; Tager, JM; van den Berg, M; van Weely, S | 1 |
| Berendsen, HJ; Huang, F; Mark, AE; Shi, YY; van Gunsteren, WF; Wang, CX | 1 |
| Fukushima, K; Hayashi, Y; Ohya, Y; Seto, T; Shikata, Y; Yoshida, Y; Yoshimatsu, K | 1 |
| Chida, Y; Kikawa, E; Nakazawa, M; Shiono, T; Tamai, M; Wada, Y | 1 |
| Appelman, EE; Bijvoet, SM; Bruin, T; Gagné, E; Groenemeyer, BE; Kromhout, D; Miao, L; Reymer, PW; Seidel, JC; van de Oever, K | 1 |
| Bause, E; Breuer, W; Peters, S | 1 |
| Dötsch, V; Oswald, RE; Wagner, G | 1 |
| Bihoreau, C; Clauser, E; Conchon, S; Corvol, P; Curnow, KM; Monnot, C | 1 |
| Arveiler, D; Bard, JM; Cambou, JP; Evans, A; Fruchart, JC; Fumeron, F; Jemaa, R; Lecerf, L; Luc, G; Poirier, O | 1 |
| Arocha-Piñango, CL; Matsuda, M; Nagaswami, C; Weisel, JW; Woodhead, JL | 1 |
| Lamphear, JG; Mollick, JA; Reda, KB; Rich, RR | 1 |
| Docherty, K; Jermany, JL; Martens, GJ; Shennan, KI | 1 |
| Angelini, GD; Birkett, S; Suleiman, MS; Wallace, D | 1 |
| Gastmann, U; Häussinger, D; Keul, J; Lehmann, M; Mann, H; Steinacker, JM; Vetter, D | 1 |
| Al-Rabiee, R; Grant, GA; Zhang, Y | 1 |
| Blackshear, PJ; Swierczynski, SL | 1 |
| Ijzerman, AP; Krasel, C; Lohse, MJ; Wieland, K; Zuurmond, HM | 1 |
| Cavanna, J; Galton, DJ; Gross, W; Marz, W; Shine, B; Winkelman, BR; Zhang, Q | 1 |
| Kernodle, DS; Tummuru, MK; Voladri, RK | 1 |
| Assmann, G; Bakker, HD; Bijvoet, SM; Bruin, T; Funke, H; Hayden, MR; Kastelein, JJ; Ma, Y; Reymer, PW; Wiebusch, H | 1 |
| Worley, PF; Yee, WM | 1 |
| Ball, SG; Balmforth, AJ; Donnelly, D; Lee, AJ; Warburton, P | 1 |
| Miyazaki, K; Oshima, T; Yaoi, T | 1 |
| McFadden, BA; Rehman, A | 1 |
| Achiwa, K; Ikeda, K; Iwamoto, Y; Ryoyama, K; Shimizu, T; Suhara, Y; Yanagihara, Y | 1 |
| Arai, K; Kajimoto, Y; Yamasaki, Y | 1 |
| Barth, A; Brandt, W; Franke, R; Frost, K; Schadler, HD; Wahab, M | 1 |
| Clausen, JO; Fridberg, M; Hansen, T; Møller, AM; Pedersen, O; Rasmussen, SK; Urhammer, SA | 1 |
| Ishizaka, K; Mikayama, T; Nakano, T; Sugie, K; Takakura, K; Tomura, T | 1 |
| Kim, DW; Lin, SJ; Matsuzawa, H; Ryugo, Y; Wakagi, T | 1 |
| Sahm, H; Sprenger, GA; Wiegert, T | 1 |
| Chen, H; Kasturi, L; Shakin-Eshleman, SH | 1 |
| Dabrosin, C; Hallström, A; Hammar, M; Ungerstedt, U | 1 |
| Deguchi, T; Kawada, Y; Kawamura, T; Nakano, M; Nishino, Y; Ozeki, S; Yasuda, M | 1 |
| Mezquita, C; Mezquita, J; Pau, M | 1 |
| Ahrenkiel, V; Gronbaek, K; Guldberg, P; Kirkin, AF; thor Straten, P; Zeuthen, J | 1 |
| Abildgaard, S; Jensen, G; Nordestgaard, BG; Steffensen, R; Tybjaerg-Hansen, A; Wittrup, HH | 1 |
| Henschen, M; Holzapfel, HP; Paschke, R; Scherbaum, WA; von Petrykowski, W; Wonerow, P | 1 |
| Baldwin, AN; Le Bivic, A; Le Gall, AH; Monlauzeur, L; Rodriguez-Boulan, E; Yeaman, C | 1 |
| Nojiri, M; Saito, T | 1 |
| Hata, S; Izui, K; Ueno, Y | 1 |
| Doerig, C; Doury, JC; Fusai, T; Parzy, D; Pradines, B; Rico, A | 1 |
| Brinkmann, AO; Burger, H; De Jong, FH; De Lange, P; Grobbee, DE; Huizenga, NA; Koper, JW; Lamberts, SW; Pols, HA; Stolk, RP | 1 |
| Kempski, OS; Kossmann, T; Lowitzsch, K; Morganti-Kossmann, MC; Pleines, UE; Stover, JF | 1 |
| Aparecida Medeiros, M; Bilharinho Mendonca, B; Correia Billerbeck, AE; Costa Frade, EM; Domenice, S; Latronico, AC; Marino Carvalho, F; Prado Arnhold, IJ; Russell, AJ; Vass, K; Yumie Nishi, M | 1 |
| Ignatov, KB; Kramarov, VM; Miroshnikov, AI | 1 |
| Lin, A; Maes, M; Scharpé, S; Vandoolaeghe, E; Verkerk, R | 1 |
| Kasturi, L; Mellquist, JL; Shakin-Eshleman, SH; Spitalnik, SL | 1 |
| Behr, J; Hellwig, P; Ludwig, B; Mäntele, W; Michel, H; Odenwald, A; Ostermeier, C; Pfitzner, U; Richter, OM | 1 |
| Nakae, T; Ono, T; Yoneyama, H; Yoshihara, E | 1 |
| Bossa, F; De Biase, D; Delle Fratte, S; di Salvo, ML; Schirch, V | 1 |
| Acosta, MC; Giraldo, LE; Krogstad, DJ; Labrada, LA; Montenegro-James, S; Praba, A; Saravia, NG | 1 |
| Davies, DR; Miles, EW; Mozzarelli, A; Rhee, S | 1 |
| Gaucher, C; Mashiba, H; Mazurier, C; Uno, H; Yamazaki, T | 1 |
| Herzberg, O; Peterkofsky, A; Zhu, PP | 1 |
| Ebihara, A; Inui, Y; Nakagawa, T; Nakamura, Y; Orihashi, T; Suzuki, F | 1 |
| Atkinson, JP; Leung, MK; Liszewski, MK | 1 |
| Takeda-Shitaka, M; Umeyama, H | 1 |
| Gancedo, C; Herrero, P; Petit, T | 1 |
| Clausen, JO; Eiberg, H; Ekstrøm, CT; Hansen, T; Møller, AM; Nyholm, B; Pedersen, O; Schmitz, O; Urhammer, SA | 1 |
| Dauter, Z; Giletto, A; Hebert, EJ; Pace, CN; Sevcik, J; Urbanikova, L; Wilson, KS | 1 |
| Munagala, NR; Wang, CC | 1 |
| Lannigan, DA; Macara, IG; Tatsis, N | 1 |
| Inoue, Y; Minagawa, J; Narusaka, Y; Satoh, K | 1 |
| Jorgensen, PL; Nielsen, JM; Pedersen, PA; Rasmussen, JH | 1 |
| Boschi-Muller, S; Branlant, G | 1 |
| Qian, H; Vijayakumar, M; Zhou, HX | 1 |
| Connolly, BA; Evans, SJ; Maughan, WN; Shipstone, EJ | 1 |
| Bashirova, AA; Ignatov, KB; Kramarov, VM; Miroshnikov, AI | 1 |
| Bowie, JU; Chen, X; Lau, FW | 1 |
| Avedian, D; Birnbaumer, M; Walsh, JH; Wu, SV; Yang, M | 1 |
| Javela, K; Jouppila, J; Juvonen, E; Kekomäki, R; Koskela, S; Nyblom, O; Partanen, J | 1 |
| Gilman, AG; Mukhopadhyay, S; Posner, BA; Ross, EM; Tesmer, JJ | 1 |
| Connors, LH; Costello, CE; Falk, RH; Skare, J; Skinner, M; Théberge, R | 1 |
| Dahlbäck, B; Nicolaes, GA; Villoutreix, BO | 1 |
| Giletto, A; Pace, CN | 1 |
| Frey, PA; Geeganage, S | 1 |
| DiOrio, JP; Matsuda, M; Meh, DA; Mimuro, J; Mosesson, MW; Nagai, K; Nakamikawa, C; Sugo, T; Takahashi, H; Takahashi, N; Takano, H; Yamaguchi, S | 1 |
| Holden, HM; Huang, X; Raushel, FM; Thoden, JB | 1 |
| Bossa, F; Delle Fratte, S; di Salvo, ML; Maras, B; Schirch, V; Wright, HT | 1 |
| Mann, K | 1 |
| Corzo, N; del Castillo, MD; Olano, A; Sanz, ML | 1 |
| Bright, JR; Campbell, ID; Dobson, CM; Penkett, CJ; Pickford, AR; Potts, JR; Smith, LJ | 1 |
| Bron, P; de Vos, WM; Kaper, T; Lebbink, JH; van der Oost, J | 1 |
| Angelova, K; Narayan, P; Puett, D; Simon, JP | 1 |
| Craen, M; de Paepe, A; Leroy, JG; Mortier, G; Nuytinck, L; Renard, JP | 1 |
| Eswar, N; Ramakrishnan, C | 1 |
| Fresno, M; Martin, AG | 1 |
| Bagshaw, R; Callahan, JW; Clarke, JT; Hilson, W; Hinek, A; Oho, Y; Zhang, S | 1 |
| Crowder, MW; Taylor, RA; Yanchak, MP | 1 |
| Al-Hendy, A; Feyles, V; Moshynska, O; Saxena, A | 1 |
| Befort, K; Decaillot, FM; Filliol, D; Gaveriaux-Ruff, C; Hoehe, MR; Kieffer, BL | 1 |
| Groop, L; Klannemark, M; Orho-Melander, M; Suurinkeroinen, L; Taskinen, MR | 1 |
| Doyle, SA; Fung, SY; Koshland, DE | 1 |
| Kraynov, VS; Liu, J; Showalter, AK; Tsai, MD; Zhong, X | 1 |
| Dumas, JJ; Lambright, DG; Lietzke, SE; Zhu, Z | 1 |
| Chanas, B; Coulter, SJ; Ghanayem, B; Goldstein, JA; Johnson, EF; Tsao, CC; Wester, MR | 1 |
| Felix, DH; Lane, EB; McLean, WH; Melino, G; Munro, CS; Rugg, EL; Terrinoni, A | 1 |
| Cerny, RL; Elthon, TE; Lund, AA; Lund, AL; Rhoads, DM | 1 |
| Jørgensen, JR; Pedersen, PA | 1 |
| Gergis, MR; Grogan, WM; Kodsi, EM; Langston, TB; Wallace, TJ | 1 |
| Krogh, BO; Shuman, S | 1 |
| Buck, DC; Cumbay, MG; DuRand, CJ; Neve, KA; Teeter, MM; Thompson, KR; Watts, VJ; Yang, R | 1 |
| Aeschliman, SM; Ballou, DP; Massey, V; Ortiz-Maldonado, M | 1 |
| Fukui, Y; Jung, YG; Lee, ES; Sakata, T | 1 |
| Chong, JM; Rubin, JS; Speicher, DW; Uren, A | 1 |
| Lamb, RA; Pekosz, A; Pinto, LH; Shuck, K; Takeda, M | 1 |
| Bergman, A; Brocchieri, L; Gentles, AJ; Karlin, S; Mrazek, J | 1 |
| Fukuda, N; Hohta, SA; Izumi, T; Kimura, A; Kurosawa, T; Sasaoka, T | 1 |
| Goto, J; Iida, H; Ikeda, M; Inoue, S; Maruoka, T; Mori, Y; Nagasoe, Y | 1 |
| Liang, J; Luba, J; McGee, MP | 1 |
| Jacobsen, MD; Jorgensen, PL; Pedersen, PA | 1 |
| Carenbauer, AL; Crowder, MW; Garrity, JD; Periyannan, G; Yates, RB | 1 |
| Harrison, NL; Jenkins, A; Nishikawa, K; Paraskevakis, I | 1 |
| Carillo, P; Gibon, Y; Krapp, A; Matt, P; Morcuende, R; Müller, C; Scheible, WR; Stitt, M | 1 |
| Funahashi, J; Takano, K; Yamagata, Y; Yutani, K | 1 |
| Asano, A; Hokiyama, H; Jin, HK; Kida, H; Ko, JH; Mizutani, M; Ninomiya, A; Nishibori, M; Ohara, M; Takada, A; Tsuzuki, M; Watanabe, T | 1 |
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| Bock, H; Hilbig, A; Jardim, LB; Michelin-Tirelli, K; Rieder, CR; Saraiva-Pereira, ML; Socal, MP | 1 |
| Bu, Z; Chen, H; Deng, G; Jiang, Y; Li, C; Ping, J; Tian, G; Zhang, S | 1 |
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| Chan, B; Eng, M; Feeney, L; Gao, A; Guo, D; Joly, J; Laird, MW; Michels, DA; Shen, A; Snedecor, B; Yu, XC; Zhang, B | 1 |
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| Chao, TL; Lee, SL; Lin, YC; Shen, WH; Tsai, ST; Tsai, WC; Wu, LW | 1 |
| Antunes, NT; Champion, MM; Frase, H; Toth, M; Vakulenko, SB | 1 |
| Gray, VE; Kumar, S | 1 |
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| Chaudhry, FA; Hamdani, el H; Nissen-Meyer, LS; Popescu, MC | 1 |
| Addad, F; Hamda, KB; Hassine, M; Jelassi, A; Jguirim, I; Maatouk, F; Najah, M; Slimane, MN; Slimani, A; Varret, M | 1 |
| Hamakubo, T; Kakamu, Y; Kondoh, M; Takahashi, A; Uchida, H; Yagi, K | 1 |
| Chen, JH; Huang, ZR; Liu, HY; Zhu, SJ | 1 |
| Biagioni, F; Fabrizi, C; Fornai, F; Fumagalli, L; Lenzi, P; Pompili, E; Somma, F | 1 |
| Han, J; Lu, H; Mei, Q; Tang, B; Zhou, D | 1 |
| Chen, CR; Kodra, JT; Liu, X; Yu, R | 1 |
| Andersen, SU; Bonetta, D; Hossain, MS; Liao, J; Parniske, M; Ross, L; Sato, S; Singh, S; Stougaard, J; Szczyglowski, K; Tabata, S; Zhou, Y | 1 |
| Baldi, M; De Sanctis, V; Marsciani, A; Ravaioli, E; Reggiani, L; Sensi, A; Timoncini, G; Zucchini, A | 1 |
| Kotaki, A; Kurane, I; Nukui, Y; Saijo, M; Sawabe, K; Tajima, S; Takasaki, T; Watanabe, H; Yamaguchi, Y | 1 |
| Smaragdov, MG | 1 |
| Hunt, DF; Jahren, N; Kim, YC; Markowski, TW; Olszewski, NE; Shabanowitz, J; Stone, MD; Udeshi, ND; Witthuhn, BA | 1 |
| Auewarakul, P; Boonarkart, C; Chakritbudsabong, W; Jongkaewwattana, A; Puthavathana, P; Siboonnan, N; Suptawiwat, O; Wiriyarat, W | 1 |
| Butler, A; Zane, HK | 1 |
| Cao, Y; Du, J; Fu, L; Huang, X; Wang, L; Xu, J; Zhang, A; Zhang, Z; Zheng, Q | 1 |
| Brown, E; Chakrabartty, A; Khan, MQ; Pai, EF; Sweeting, B | 1 |
| Alwan, A; Bathe, M; Boyer, LA; Butty, VL; Fields, PA; Levine, SS; Mazumder, A; Subramanian, V; Surface, LE; Thai, KK; Torrey, L | 1 |
| Andrade-Navarro, MA; Brauns, K; Vlassi, M | 1 |
| Fransen van de Putte, DE; Mauser-Bunschoten, EP; Ploos van Amstel, HK; Schutgens, RE; Spoor, M | 1 |
| Gopi, HN; Jadhav, SV; Misra, R; Singh, SK | 1 |
| Akten, ED; Doruker, P; Ozcan, O; Uyar, A | 1 |
| Cronan, JE; Feng, Y; Henke, SK; Manandhar, M; Napier, BA; Weiss, DS | 1 |
| Alves, PM; Barreiro, LC; Carinhas, N; Carrondo, MJ; Duarte, TM; Teixeira, AP | 1 |
| Du, J; Hong, L; Huang, X; Li, L; Shi, H; Sun, X; Zhang, H; Zhang, Z; Zhou, W | 1 |
| Chau, JK; Chung, M; Frank, CB; Hart, DA; Heard, BJ; Mickiewicz, B; Shrive, NG; Vogel, HJ | 1 |
| Chung, HY; Li, CC | 1 |
| Barvík, I; Hynkova, A; Vlachova, V; Witschas, K; Zíma, V; Zímová, L | 1 |
| Bisconte, MG; Caldora, M; Cardiero, G; Flagiello, A; Gaudiano, C; La Porta, G; Lacerra, G; Lagona, L; Medulla, E; Merlino, A; Musollino, G; Prezioso, R; Pucci, P; Qualtieri, G | 1 |
| Fukada, R; Kugimiya, A | 1 |
| Fukutake, N; Hiraoka, N; Imaizumi, A; Ito, T; Katayama, K; Kikuchi, S; Ono, N; Saruki, N; Shimada, K; Shiraishi, K; Ueno, M; Yamakado, M; Yamamoto, H | 1 |
| Brannagan, TH; Brown, RS; Castano, A; Dixit, N; Farr, MJ; Lentzsch, S; Maurer, MS; Traub, R | 1 |
| DeGrado, WF; Thomaston, JL | 1 |
| Braas, D; Christofk, HR; Graeber, TG; Krall, AS; Xu, S | 1 |
| Ide, M; Irie, M; Kamikawa, T; Kashiwagi, H; Miura, T; Morikami, K; Muraoka, T; Nakamura, M; Nishihara, M | 1 |
| Bowness, P; Chen, L; Shi, H; Yuan, J | 1 |
| Bauwe, H; Fernie, AR; Florian, A; Michl, K; Modde, K; Timm, S | 1 |
| Carpenter, MC; Ely, F; Gahan, LR; Mitić, N; Ollis, DL; Pedroso, MM; Schenk, G; Wilcox, DE | 1 |
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| Bueno-Gil, G; Dávila, JC; Espadas, I; Fuentes, JM; García-Sanz, P; González-Polo, RA; Gutierrez, A; Kulisevsky, J; Mir, P; Moratalla, R; Orgaz, L; Rodríguez-Traver, E; Vicario, C | 1 |
| Ashcroft, J; Barker, JN; Barton, A; Bellou, E; Bowes, J; Brown, MA; Dand, N; Feletar, M; FitzGerald, O; Helliwell, PS; Ho, P; Jalali-Najafabadi, F; Kane, DJ; Korendowych, E; Marzo-Ortega, H; McHugh, N; McManus, R; Packham, J; Ryan, AW; Simpson, MA; Smith, CH; Warren, RB | 1 |
| Cheng, ML; Deng, YQ; Hu, B; Huang, XY; Ji, X; Li, C; Li, G; Li, XF; Liu, ZY; Qin, CF; Shi, PY; Shi, W; Wang, HJ; Wang, X; Wu, M; Xie, DY; Xu, YP; Xu, Z; Ye, Q; Yu, JY; Yuan, L; Zhang, F; Zhu, XL | 1 |
| Ito, S; Kashiwagi, K; Kato, G; Maeda, S | 1 |
| Katahira, M; Kondo, K; Mikami, B; Nagata, T; Saka, N; Wan Osman, WH | 1 |
| Garip, B; Kayir, H | 1 |
| Alatrash, N; Armstrong, DW; Berthod, A; Du, S; MacDonnell, FM; Sung, YS; Wang, Y; Wey, M | 1 |
| Ahmad-Hamdani, MS; Mazlan, N; Ruzmi, R | 1 |
| Cazier, JB; Eraslan, Z; Günther, UL; Khanim, FL; Papatzikas, G | 1 |
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| Ayoubi, JM; de Ziegler, D; Franasiak, J; Marin, D; Pirtea, P; Scott, RT; Sun, L; Tao, X | 1 |
| Li, R; Shi, W; Yan, Z; Yao, L | 1 |
| Chen, X; Ge, T; He, Z; Wang, J; Yuan, H; Zhang, L | 1 |
| Ates, O; Toker, EB; Yesilbag, K | 1 |
| Cai, Y; Deng, Z; Hao, H; Li, S; Shi, C; Song, J; Yang, Q; Zhuang, G | 1 |
19 review(s) available for serine and asparagine
| Article | Year |
|---|---|
Aminotransferase activity in brain.
Topics: Alanine Transaminase; Animals; Asparagine; Aspartate Aminotransferases; Brain; Catalysis; Chemical Phenomena; Chemistry; Diet; gamma-Aminobutyric Acid; Glucose; Glutamine; Glycine; Hormones; Humans; Isoenzymes; Ketoglutaric Acids; Ornithine; Rats; Serine; Swine; Transaminases; Tyrosine Transaminase | 1975 |
Synthetic N- and O-glycosyl derivatives of L-asparagine, L-serine, and L-threonine.
Topics: Asparagine; Carbohydrate Conformation; Chemical Phenomena; Chemistry; Circular Dichroism; Glycosides; Hydrolysis; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Optical Rotatory Dispersion; Serine; Structure-Activity Relationship; Threonine | 1985 |
Glycoproteins.
Topics: Amino Acid Sequence; Asparagine; Carbohydrates; Cysteine; Glucosamine; Glycoproteins; Hydroxylysine; Models, Structural; Mucins; Polyribosomes; Protein Conformation; Serine; Threonine | 1972 |
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Invariant features of globin primary structure and coding of their secondary structure.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Globins; Glycine; Hemoglobins; Histidine; Myoglobin; Proline; Protein Conformation; Serine; Species Specificity; Threonine; Tyrosine | 1974 |
Glycoproteins.
Topics: Amino Acids; Animals; Asparagine; Carbohydrate Metabolism, Inborn Errors; Carbohydrates; Chemical Phenomena; Chemistry; Enzymes; Glycoproteins; Hydroxyproline; Kinetics; Lysine; Polysaccharides; Serine; Threonine; Transferases | 1970 |
[Synthesis of peptides by solid phase method. 1].
Topics: Arginine; Asparagine; Cysteine; Esters; Glutamine; Histidine; Lysine; Methionine; Methods; Peptides; Polystyrenes; Serine; Threonine | 1971 |
Glycosylation mutants of animal cells.
Topics: Animals; Asparagine; Carbohydrate Metabolism; Carbohydrate Sequence; Cell Line; Ceramides; Cerebrosides; Cricetinae; Glucosyltransferases; Glycolipids; Glycoproteins; Glycosphingolipids; Lectins; Mammals; Mice; Mutation; Proteins; Receptors, Mitogen; Serine; Threonine | 1984 |
Sugar residues on proteins.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Carbohydrates; Chemical Phenomena; Chemistry; Chorionic Gonadotropin; Glycopeptides; Glycoproteins; Glycoside Hydrolases; Glycosides; Humans; Hydrolysis; Male; Membrane Proteins; Methylation; Molecular Biology; Oxidation-Reduction; Receptors, Cell Surface; Receptors, LH; Serine | 1981 |
In vivo chemical modification of proteins (post-translational modification).
Topics: Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Glutamates; Glutamine; Histidine; Hydroxylysine; Lysine; Phenylalanine; Proline; Protein Biosynthesis; RNA, Transfer, Amino Acyl; Serine; Threonine; Tryptophan; Tyrosine | 1981 |
Developments in the synthesis of glycopeptides containing glycosyl L-asparagine, L-serine, and L-threonine.
Topics: Amino Acid Sequence; Asparagine; Carbohydrate Sequence; Enzymes; Glycopeptides; Glycosylation; Molecular Sequence Data; Protein Binding; Serine; Stereoisomerism; Threonine | 1994 |
Steps towards an integrated view of nitrogen metabolism.
Topics: Amino Acid Oxidoreductases; Amino Acids; Asparagine; Cysteine; Gene Expression Regulation, Plant; Glutamate Dehydrogenase; Glutamine; Glycine; Ketoglutaric Acids; Malates; Nicotiana; Nitrate Reductase; Nitrate Reductases; Nitrates; Nitrogen; Oxidation-Reduction; Quaternary Ammonium Compounds; Serine; Signal Transduction | 2002 |
[Function and metabolism of D-amino acids in eukaryotes].
Topics: Animals; Asparagine; Eukaryotic Cells; Humans; Melatonin; Prolactin; Racemases and Epimerases; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Serine; Testosterone | 2004 |
A systematic review and meta-analysis of the relationship between lipoprotein lipase Asn291Ser variant and diseases.
Topics: Amino Acid Substitution; Asparagine; Coronary Disease; Diabetes Mellitus, Type 2; Dyslipidemias; Humans; Lipoprotein Lipase; Models, Molecular; Protein Structure, Tertiary; Serine | 2006 |
Human prostacyclin receptor structure and function from naturally-occurring and synthetic mutations.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Cysteine; Models, Molecular; Molecular Sequence Data; Mutation; Nuclear Magnetic Resonance, Biomolecular; Palmitic Acid; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Proline; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Epoprostenol; Serine | 2007 |
[Nucleotide sequence variants of the glucocorticoid receptor gene and their significance in determining glucocorticoid sensitivity].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Asparagine; Base Sequence; Female; Glucocorticoids; Humans; Lasers, Excimer; Male; Mutation; Ocular Hypertension; Phenotype; Photorefractive Keratectomy; Polymorphism, Genetic; Protein Isoforms; Receptors, Glucocorticoid; Retrospective Studies; Serine | 2006 |
Flexible structures and ligand interactions of tandem repeats consisting of proline, glycine, asparagine, serine, and/or threonine rich oligopeptides in proteins.
Topics: Animals; Asparagine; Glycine; Humans; Ligands; Oligopeptides; Proline; Protein Conformation; Proteins; Serine; Tandem Repeat Sequences; Threonine | 2008 |
CYP1B1 Asn453Ser polymorphism and colorectal cancer risk: a meta-analysis.
Topics: Aryl Hydrocarbon Hydroxylases; Asparagine; Case-Control Studies; Colorectal Neoplasms; Confounding Factors, Epidemiologic; Cytochrome P-450 CYP1B1; Genetic Predisposition to Disease; Humans; Odds Ratio; Polymorphism, Single Nucleotide; Risk Assessment; Risk Factors; Serine; White People | 2012 |
Amino acid synthesis deficiencies.
Topics: Abnormalities, Multiple; Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Asparagine; Brain Diseases; Central Nervous System; Fetal Growth Retardation; Glutamine; High-Throughput Nucleotide Sequencing; Humans; Ichthyosis; Limb Deformities, Congenital; Metabolic Diseases; Mice; Microcephaly; Proline; Serine | 2017 |
3 trial(s) available for serine and asparagine
| Article | Year |
|---|---|
Rarity of the Asn291Ser mutation of lipoprotein lipase gene in Japanese NIDDM patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asparagine; Diabetes Mellitus, Type 2; Female; Gene Frequency; Humans; Japan; Lipoprotein Lipase; Male; Middle Aged; Point Mutation; Serine | 1997 |
Serum levels of excitatory amino acids, serine, glycine, histidine, threonine, taurine, alanine and arginine in treatment-resistant depression: modulation by treatment with antidepressants and prediction of clinical responsivity.
Topics: Adult; Aged; Alanine; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arginine; Asparagine; Aspartic Acid; Depressive Disorder, Major; Drug Resistance; Drug Therapy, Combination; Excitatory Amino Acids; Female; Fluoxetine; Glycine; Histidine; Humans; Male; Middle Aged; Personality Inventory; Pindolol; Prognosis; Selective Serotonin Reuptake Inhibitors; Serine; Taurine; Threonine; Trazodone; Treatment Outcome | 1998 |
A possible association between missense polymorphism of the breakpoint cluster region gene and lithium prophylaxis in bipolar disorder.
Topics: Adult; Analysis of Variance; Antimanic Agents; Asparagine; Bipolar Disorder; Brief Psychiatric Rating Scale; Female; Gene Frequency; Genotype; Humans; Lithium Compounds; Male; Middle Aged; Mutation, Missense; Pharmacogenetics; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins c-bcr; Serine | 2008 |
480 other study(ies) available for serine and asparagine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Effects of pH on the olfactory responses to amino acids in rainbow trout, Salmo gairdneri.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Electric Conductivity; Hydrogen-Ion Concentration; Methionine; Olfactory Bulb; Salmonidae; Serine; Smell; Trout | 1976 |
Effect of amino acid meals on hepatic alpha-aminoisobutyrate transport and cyclic AMP.
Topics: Adrenalectomy; Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Asparagine; Biological Transport; Caseins; Cyclic AMP; Diet; Electrolytes; Gelatin; Glutamine; Glycine; Inulin; Liver; Male; Protein Hydrolysates; Rats; Serine; Sodium Glutamate; Stimulation, Chemical | 1975 |
N-terminal amino acid sequences in the major capsid proteins of foot-and-mouth disease virus types A, O, and C.
Topics: Amino Acid Sequence; Amino Acids; Aphthovirus; Asparagine; Aspartic Acid; Dansyl Compounds; Glycine; Leucyl Aminopeptidase; Serine; Serotyping; Threonine; Viral Proteins | 1975 |
Some observations on why many proteins are glycosylated.
Topics: Asparagine; Glycoproteins; Glycosides; Hemoglobin A; Humans; Proteoglycans; Serine; Threonine | 1979 |
HB Beth Israel (beta 102 [G4] Asn replaced by Ser) observed in a Yugoslavian teenager.
Topics: Adolescent; Asparagine; Hemoglobins, Abnormal; Humans; Israel; Male; Serine; Yugoslavia | 1978 |
Turnover of amino-terminal acetylated and non-acetylated hemoglobins in vivo.
Topics: Acetates; Animals; Arginine; Asparagine; Blood Cell Count; Cats; Glycine; Hematocrit; Hemoglobins; Hemoglobins, Abnormal; Kinetics; Lysine; Phenotype; Reticulocytes; Serine; Time Factors | 1976 |
Amino acid metabolism in Friedreich's ataxia.
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Friedreich Ataxia; Glycine; Histidine; Humans; Isoleucine; Ornithine; Phenylalanine; Phosphatidylethanolamines; Sarcosine; Serine; Taurine; Tyrosine; Valine | 1976 |
Studies on convulsants in the isolated frog spinal cord. I. Antagonism of amino acid responses.
Topics: Alanine; Amino Acids; Aminocaproates; Aminoisobutyric Acids; Animals; Asparagine; Bicuculline; Convulsants; Cystathionine; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Imidazoles; In Vitro Techniques; Isomerism; Leucine; Membrane Potentials; Nerve Endings; Neurons, Afferent; Picrotoxin; Rana pipiens; Serine; Spinal Cord; Strychnine; Taurine; Threonine; Valine | 1975 |
Effect of Acinetobacter glutaminase-asparaginase treatment on free amino acids in mouse tissues.
Topics: Acetyltransferases; Acinetobacter; Amino Acids; Ammonia; Animals; Asparaginase; Asparagine; Aspartic Acid; Body Weight; Brain; Escherichia coli; Female; Glutamates; Glutaminase; Glutamine; Kidney; Mice; Organ Size; Serine; Spleen; Threonine | 1975 |
The terminal amino acids of protein sequences and protein maturation.
Topics: Alanine; Amino Acid Sequence; Asparagine; Cell Nucleus; Codon; Glutamine; Lysine; Methionine; Peptide Chain Termination, Translational; Peptide Hydrolases; Phenylalanine; Protein Biosynthesis; Serine | 1975 |
On the mechanism of action of antibiotics which act as irreversible enzyme inhibitors.
Topics: Alanine; Anti-Bacterial Agents; Asparagine; Azaserine; Azo Compounds; Carbamates; Catalysis; Cell Wall; Cephalosporins; Cycloserine; Diazooxonorleucine; Enzyme Inhibitors; Glutamine; Models, Chemical; Models, Molecular; Penicillins; Purines; Pyridoxal Phosphate; Pyrimidines; Racemases and Epimerases; Serine | 1975 |
Synthesis by conventional methods of human growth hormone peptide fragments. I.
Topics: Alanine; Asparagine; Aspartic Acid; Glutamine; Growth Hormone; Histidine; Humans; Leucine; Lysine; Optical Rotation; Peptides; Phenylalanine; Serine; Threonine; Tyrosine | 1975 |
[Some indices of nitrogen metabolism in patients with viral hepatitis].
Topics: Adolescent; Adult; Alanine; Ammonia; Asparagine; Chronic Disease; Cysteine; Cystinuria; Glutamates; Glycine; Hepatitis A; Humans; Isoleucine; Leucine; Methionine; Middle Aged; Nitrogen; Phenylalanine; Serine; Threonine; Urea; Valine | 1975 |
Characterization of the stabilizing effect of point mutations of pyruvate oxidase from Lactobacillus plantarum: protection of the native state by modulating coenzyme binding and subunit interaction.
Topics: Alanine; Amino Acid Sequence; Asparagine; Enzyme Stability; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Kinetics; Lactobacillus; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Proline; Protein Denaturation; Pyruvate Oxidase; Recombinant Proteins; Serine; Spectrophotometry, Ultraviolet; Thiamine Pyrophosphate; Urea; Valine | 1992 |
Human lipoprotein lipase. Analysis of the catalytic triad by site-directed mutagenesis of Ser-132, Asp-156, and His-241.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Blotting, Northern; Catalysis; Cells, Cultured; Chromatography, Affinity; DNA; Histidine; Humans; Kidney; Lipoprotein Lipase; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Hybridization; Plasmids; RNA; Serine | 1992 |
Seizure related elevations of extracellular amino acids in human focal epilepsy.
Topics: Amino Acids; Asparagine; Aspartic Acid; Cerebral Cortex; Dialysis; Electroencephalography; Epilepsies, Partial; Extracellular Space; Glutamates; Glycine; Humans; Seizures; Serine | 1992 |
The role of anticodon bases and the discriminator nucleotide in the recognition of some E. coli tRNAs by their aminoacyl-tRNA synthetases.
Topics: Amino Acyl-tRNA Synthetases; Anticodon; Asparagine; Bacteriophage T7; Base Sequence; Cysteine; DNA-Directed RNA Polymerases; Escherichia coli; Glycine; Histidine; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Transfer; Serine; Structure-Activity Relationship; Substrate Specificity | 1992 |
Effects of substitutions of glycine and asparagine for serine132 on activity and binding of human lipoprotein lipase to very low density lipoproteins.
Topics: Amino Acid Sequence; Animals; Asparagine; Base Sequence; Catalysis; Cells, Cultured; Chlorocebus aethiops; Cross Reactions; Enzyme Activation; Glycine; Humans; Lipoprotein Lipase; Lipoproteins, VLDL; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Serine; Triolein | 1992 |
A mutation in the putative Mg(2+)-binding site of Gs alpha prevents its activation by receptors.
Topics: Adenylyl Cyclases; Animals; Asparagine; Binding Sites; Blotting, Northern; Cyclic AMP; Enzyme Activation; Gene Expression Regulation, Enzymologic; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Magnesium; Mice; Mutation; Oncogene Protein p21(ras); Serine; Tumor Cells, Cultured | 1991 |
Oxytocin antagonists with changes in the Asn5 position shed light on hormone-oxytocin receptor interactions.
Topics: Amino Acid Sequence; Animals; Asparagine; Drug Combinations; Female; Glutamine; Molecular Sequence Data; Oxytocin; Pregnancy; Rabbits; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Oxytocin; Serine; Structure-Activity Relationship; Uterine Contraction | 1991 |
An A alpha Ser-434 to N-glycosylated Asn substitution in a dysfibrinogen, fibrinogen Caracas II, characterized by impaired fibrin gel formation.
Topics: Amino Acids; Asparagine; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Fibrin; Fibrinogen; Fibrinogens, Abnormal; Glycosylation; Humans; Mutation; Oligosaccharides; Oxidation-Reduction; Serine; Thrombin; Tissue Plasminogen Activator; Transglutaminases | 1991 |
Glycosylation of synthetic peptides breaks helices. Phosphorylation results in distorted structure.
Topics: Antigens, Viral; Asparagine; Circular Dichroism; Epitopes; Glycoproteins; Glycosylation; Molecular Conformation; Peptide Fragments; Phosphorylation; Serine; Viral Envelope Proteins | 1991 |
A novel polymorphism of apolipoprotein A-IV is the result of an asparagine to serine substitution at residue 127.
Topics: Alleles; Amino Acid Sequence; Apolipoproteins A; Asparagine; Base Sequence; Cholesterol; Codon; Genotype; Humans; Hyperlipidemias; Lipoproteins; Male; Molecular Sequence Data; Myocardial Infarction; Polymorphism, Genetic; Serine; Threonine; Triglycerides | 1992 |
The dysfunctional LDL receptor in a monensin-resistant mutant of Chinese hamster ovary cells lacks selected O-linked oligosaccharides.
Topics: Acetylgalactosamine; Acetylglucosamine; Animals; Asparagine; Carbohydrate Conformation; Cell Line; Cricetinae; Cricetulus; Drug Resistance; Female; Glycopeptides; Glycosylation; Humans; Monensin; Mutation; Oligosaccharides; Receptors, LDL; Serine; Threonine | 1991 |
Erythrocyte Webb-type glycophorin C variant lacks N-glycosylation due to an asparagine to serine substitution.
Topics: Amino Acids; Asparagine; Blood Group Antigens; Blotting, Western; DNA; Erythrocytes; Genetic Variation; Glycophorins; Glycosylation; Humans; Immune Sera; Mutation; Phenotype; Polymerase Chain Reaction; Serine | 1991 |
Degradation of growth hormone releasing factor analogs in neutral aqueous solution is related to deamidation of asparagine residues. Replacement of asparagine residues by serine stabilizes.
Topics: Amides; Animals; Asparagine; Cattle; Drug Stability; Growth Hormone; Growth Hormone-Releasing Hormone; In Vitro Techniques; Pituitary Gland; Serine; Solutions; Water | 1991 |
Secondary structure and side-chain 1H and 13C resonance assignments of calmodulin in solution by heteronuclear multidimensional NMR spectroscopy.
Topics: Alanine; Amino Acid Sequence; Amino Acids, Branched-Chain; Amino Acids, Diamino; Amino Acids, Dicarboxylic; Animals; Asparagine; Binding Sites; Calcium; Calmodulin; Drosophila melanogaster; Glutamine; Glycine; Hydrogen Bonding; Leucine; Magnetic Resonance Spectroscopy; Methionine; Molecular Sequence Data; Molecular Structure; Proline; Recombinant Proteins; Serine; Solutions; Threonine | 1991 |
Substitution of asparagine for serine-406 of the immunoglobulin mu heavy chain alters glycosylation at asparagine-402.
Topics: Amino Acid Sequence; Animals; Asparagine; Cell Line; Glycosylation; Immunoglobulin Heavy Chains; Immunoglobulin M; Immunoglobulin mu-Chains; Mice; Oligosaccharides; Peptide Mapping; Protein Processing, Post-Translational; Serine | 1991 |
C1 binding by mouse IgM. The effect of abnormal glycosylation at position 402 resulting from a serine to asparagine exchange at residue 406 of the mu-chain.
Topics: Amino Acid Sequence; Asparagine; Complement C1; Glycosylation; Humans; Immunoglobulin M; Immunoglobulin mu-Chains; Kinetics; Molecular Sequence Data; Mutation; Osmolar Concentration; Protein Binding; Serine | 1990 |
[Conformation analysis of the N-glycosylation site Asn-X-Thr/Ser in glycoproteins].
Topics: Amino Acid Sequence; Asparagine; Glycolipids; Glycoproteins; Glycosylation; Models, Molecular; Molecular Sequence Data; Protein Conformation; Serine; Threonine | 1990 |
Mutagenic, electrochemical, and crystallographic investigation of the cytochrome b5 oxidation-reduction equilibrium: involvement of asparagine-57, serine-64, and heme propionate-7.
Topics: Amino Acid Sequence; Animals; Asparagine; Base Sequence; Cattle; Cytochromes b5; DNA; Electrochemistry; Escherichia coli; Heme; Molecular Sequence Data; Mutation; Oxidation-Reduction; Protein Conformation; Serine; X-Ray Diffraction | 1990 |
Role of the conserved amino acids of the 'SDN' loop (Ser130, Asp131 and Asn132) in a class A beta-lactamase studied by site-directed mutagenesis.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Base Sequence; beta-Lactamases; Binding Sites; Chemical Phenomena; Chemistry, Physical; Enzyme Stability; Hot Temperature; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Penicillanic Acid; Serine; Streptomyces; Structure-Activity Relationship; Thermodynamics | 1990 |
The proton pore of the F0F1-ATPase of Escherichia coli: Ser-206 is not required for proton translocation.
Topics: Alanine; Amino Acid Sequence; Asparagine; Base Sequence; Dicyclohexylcarbodiimide; DNA Restriction Enzymes; DNA, Bacterial; Escherichia coli; Fluorescence; Glutamine; Ion Channels; Oxidative Phosphorylation; Proton-Translocating ATPases; Protons; Quinacrine; Serine | 1988 |
Transport characteristics of glutamine in human intestinal brush-border membrane vesicles.
Topics: Asparagine; Biological Transport; Electrochemistry; Glutamine; Humans; Intestinal Absorption; Kinetics; Male; Membrane Potentials; Microvilli; Middle Aged; Osmolar Concentration; Potassium; Serine; Sodium; Temperature; Valinomycin | 1989 |
Transport of glutamine in rat intestinal brush-border membrane vesicles.
Topics: Animals; Asparagine; Biological Transport; Electrochemistry; Glutamine; Intestinal Mucosa; Kinetics; Male; Membrane Potentials; Microvilli; Osmolar Concentration; Potassium; Potassium Chloride; Rats; Rats, Inbred Strains; Serine; Sodium; Thiocyanates; Valinomycin | 1989 |
Point mutations at threonine-301 modify substrate specificity of rabbit liver microsomal cytochromes P-450 (laurate (omega-1)-hydroxylase and testosterone 16 alpha-hydroxylase).
Topics: Amino Acid Sequence; Animals; Aryl Hydrocarbon Hydroxylases; Asparagine; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Decanoic Acids; DNA; Isoleucine; Lauric Acids; Microsomes, Liver; Mixed Function Oxygenases; Mutation; Progesterone; Rabbits; Saccharomyces cerevisiae; Serine; Spectrophotometry; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Structure-Activity Relationship; Substrate Specificity; Testosterone; Threonine; Transformation, Genetic; Valine | 1989 |
In vitro mutagenesis of the herpes simplex virus type 1 DNA polymerase gene results in altered drug sensitivity of the enzyme.
Topics: Amino Acid Sequence; Antiviral Agents; Aphidicolin; Asparagine; Base Sequence; Diterpenes; DNA-Directed DNA Polymerase; Foscarnet; Genes, Viral; Genetic Vectors; HeLa Cells; Humans; Kinetics; Molecular Sequence Data; Mutation; Nucleic Acid Synthesis Inhibitors; Oligonucleotide Probes; Phosphonoacetic Acid; Saccharomyces cerevisiae; Serine; Simplexvirus; Viral Structural Proteins | 1989 |
Effect of impact trauma on neurotransmitter and nonneurotransmitter amino acids in rat spinal cord.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kinetics; Laminectomy; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Serine; Spinal Cord; Spinal Cord Injuries; Taurine; Threonine | 1989 |
The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis.
Topics: Animals; Asparagine; Aspartic Acid; Binding Sites; Cattle; Computer Simulation; Crystallography; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Protein Conformation; Rats; Serine; Structure-Activity Relationship; Trypsin | 1987 |
The effects of vitamin B-6 deficiency in chronically azotemic and sham-operated rats.
Topics: Alanine; Animals; Asparagine; Aspartate Aminotransferases; Chronic Disease; Creatinine; Erythrocytes; Glycine; Rats; Serine; Urea; Uremia; Vitamin B 6 Deficiency | 1987 |
Yeast mutants temperature-sensitive for growth after random mutagenesis of the chromosomal RAS2 gene and deletion of the RAS1 gene.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Base Sequence; Carbon; Chromosome Deletion; Cloning, Molecular; Culture Media; DNA, Fungal; Fungal Proteins; Galactose; Genes, ras; Glucose; Glycine; Immunoblotting; Molecular Sequence Data; Mutation; Phenotype; ras Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Temperature; Transformation, Genetic | 1988 |
Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.
Topics: Animals; Asparagine; Cell Division; Cells, Cultured; Cloning, Molecular; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Membrane Proteins; Mice; Mice, Inbred Strains; Mutation; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Serine; Transfection | 1988 |
Function of arginine-234 and aspartic acid-271 in domain closure, cooperativity, and catalysis in Escherichia coli aspartate transcarbamylase.
Topics: Arginine; Asparagine; Aspartate Carbamoyltransferase; Aspartic Acid; Escherichia coli; Kinetics; Models, Molecular; Mutation; Plasmids; Protein Conformation; Serine | 1988 |
Mechanisms of chain initiation in the biosynthesis of connective tissue polysaccharides.
Topics: Acetylgalactosamine; Acetylglucosamine; Animals; Asparagine; Connective Tissue; Endoplasmic Reticulum; Golgi Apparatus; Hyaluronic Acid; Keratan Sulfate; Oligopeptides; Pentosyltransferases; Polysaccharides; Proteoglycans; Serine; Substrate Specificity; Threonine; UDP Xylose-Protein Xylosyltransferase; Xylose | 1985 |
Comparison of glycine metabolism in mouse lymphoma cells either sensitive or resistant to L-asparaginase.
Topics: Animals; Asparaginase; Asparagine; Chromatography, High Pressure Liquid; Drug Resistance; Glycine; Glyoxylates; Leukemia L5178; Leukemia, Experimental; Mice; Serine | 1985 |
Respiratory syncytial virus polypeptides. IV. The oligosaccharides of the glycoproteins.
Topics: Asparagine; Glycoproteins; Glycoside Hydrolases; HeLa Cells; Humans; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Monensin; Oligosaccharides; Respiratory Syncytial Viruses; Serine; Threonine; Tunicamycin; Viral Proteins | 1985 |
[Development of two assay systems of desialylated hCG specific for O-serine or N-asparagine linked carbohydrate chain and their clinical application].
Topics: Asialoglycoproteins; Asparagine; Choriocarcinoma; Chorionic Gonadotropin; Chromatography, Gel; Female; Galectins; Hemagglutinins; Humans; Lectins; Molecular Weight; Peanut Agglutinin; Peptide Fragments; Pregnancy; Radioimmunoassay; Serine; Uterine Neoplasms | 1985 |
The activation of Mg++-dependent ATPase by aspartic and glutamic acids.
Topics: Adenosine Triphosphatases; Alanine; Asparagine; Aspartic Acid; Cell Membrane; Cell Membrane Permeability; Depression, Chemical; Enzyme Activation; Erythrocytes; Glutamates; Glutamine; Glycine; Humans; In Vitro Techniques; Leucine; Magnesium; Potassium; Saponins; Serine; Sodium | 1970 |
Comparison of the amino acid sequences of the variable regions of light chains derived from two homogeneous rabbit anti-pneumococcal antibodies.
Topics: Aconitic Acid; Alanine; Amino Acid Sequence; Amino Acids; Animals; Antibodies, Bacterial; Asparagine; Aspartic Acid; Autoanalysis; Chromatography, Gel; Electrophoresis, Paper; Glutamates; Glycine; Hydrolysis; Immunoglobulin Fragments; Rabbits; Serine; Streptococcus pneumoniae; Threonine; Tyrosine; Valine | 1974 |
Chromatographic analysis of the bleeding sap of inoculated and non-inoculated soya plants.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; Chromatography, Paper; Glutamine; Glycine max; Injections; Leucine; Nitrogen; Rhizobium; Serine; Valine | 1967 |
The structure of the cell wall peptidoglycan of Bifidobacterium bifidum var. pennsylvanicus.
Topics: Alanine; Amino Acids; Ammonia; Asparagine; Cell Wall; Chromatography, Gel; Chromatography, Paper; Cycloserine; Dinitrophenols; Electrophoresis; Fluorine; Glucosamine; Glutamine; Glycosaminoglycans; Hydrazines; Hydrolysis; Lactobacillus; Models, Structural; Muramidase; Nucleoside Diphosphate Sugars; Ornithine; Paper; Peptides; Polysaccharides, Bacterial; Serine; Species Specificity; Stereoisomerism; Uracil Nucleotides | 1971 |
Carbohydrate-peptide linkages in glycoproteins and mucopolysaccharides from brain.
Topics: Acetates; Animals; Asparagine; Borohydrides; Brain; Cattle; Chondroitin; Chromatography, Gel; Galactosamine; Glucosamine; Glycoproteins; Glycosaminoglycans; Heparitin Sulfate; Molecular Conformation; Protein Binding; Rabbits; Rats; Serine; Sulfuric Acids; Threonine | 1972 |
[Studies of chemically defined culture media for Pasteurella multocida and P. haemolytica].
Topics: Arginine; Asparagine; Bacteriological Techniques; Culture Media; Cystine; Glucose; Glutamates; Hydrogen-Ion Concentration; Magnesium Sulfate; Niacinamide; Orotic Acid; Pantothenic Acid; Pasteurella; Peptones; Phosphates; Saccharomyces; Serine; Sodium Chloride | 1974 |
Cyanide metabolism in higher plants. 3. The biosynthesis of beta-cyanolanine.
Topics: Alanine; Amino Acids; Asparagine; Carbon Isotopes; Colorimetry; Cyanides; Cysteine; Hydro-Lyases; Hydrogen Cyanide; Plants; Serine; Stimulation, Chemical | 1968 |
The carbohydrate sequence of the glycopeptide chains of human transferrin.
Topics: Asparagine; Carbohydrates; Chromatography, DEAE-Cellulose; Chromatography, Gas; Chromatography, Gel; Disaccharides; Formaldehyde; Formates; Galactose; Galactosidases; Glycine; Glycopeptides; Glycoside Hydrolases; Humans; Hydrolysis; Mannose; Methylation; Neuraminic Acids; Periodic Acid; Serine; Threonine; Transferrin | 1971 |
Glycopeptides from silk fibroin of Bombyx mori.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Bombyx; Boron Compounds; Chromatography, Gel; Chromatography, Ion Exchange; Fibroins; Glucosamine; Glycine; Glycopeptides; Hydrolysis; Mannose; Molecular Weight; Oxidation-Reduction; Peptide Hydrolases; Peptides; Periodic Acid; Serine; Thiocyanates; Threonine; Trypsin | 1971 |
The isolation and the structure of new glycopeptide from blood group substances.
Topics: Acetamides; Alanine; Asparagine; Blood Group Antigens; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis, Paper; Galactosamine; Glucosamine; Glycopeptides; Humans; Optical Rotation; Oxidation-Reduction; Periodic Acid; Proline; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet | 1974 |
Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. I. Effect of amino acid supply.
Topics: Amino Acids; Animals; Arginine; Asparagine; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Culture Media; Cycloheximide; Drug Synergism; Glutamine; Glycine; Immune Sera; Leucine; Liver Neoplasms; Neoplasm Proteins; Ornithine; Proline; Pyridoxal; Rats; Serine; Stimulation, Chemical; Time Factors | 1974 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
[Studies of the chemically defined media for Pasteurella multocida and P. haemolytica].
Topics: Arginine; Asparagine; Cell Division; Culture Media; Cystine; Glucose; Glutamine; Hydrogen-Ion Concentration; Magnesium Sulfate; Nicotinic Acids; Orotic Acid; Pantothenic Acid; Pasteurella; Phosphates; Plant Growth Regulators; Serine; Sodium Chloride; Stereoisomerism | 1974 |
[Amino acid concentration in plasma and blood cells during coli-L-asparaginase therapy].
Topics: Alanine; Amino Acids; Asparaginase; Asparagine; Autoanalysis; Erythrocytes; Glutamates; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Plasma; Serine; Time Factors | 1972 |
A sensitive double isotope derivative assay to measure release of amino acids from brain in vitro.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Asparagine; Carbon Isotopes; Cerebral Cortex; Dansyl Compounds; Electric Stimulation; Glutamates; Glycine; In Vitro Techniques; Isotope Labeling; Methods; Rats; Serine; Tritium; Valine | 1973 |
The presence of N-(purin-6-ylcarbamoyl)threonine in transfer ribonucleic acid species whose codons begin with adenine.
Topics: Adenine; Amino Acyl-tRNA Synthetases; Arginine; Asparagine; Benzoates; Carbamates; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Electrophoresis, Paper; Escherichia coli; Genetic Code; Glycolates; Isoleucine; Leucine; Lysine; Methionine; Purine Nucleotides; RNA, Bacterial; RNA, Transfer; Serine; Succinimides; Threonine; Tritium | 1972 |
Nitrogen repression of the allantoin degradative enzymes in Saccharomyces cerevisiae.
Topics: Alanine; Allantoin; Amidohydrolases; Amino Acids; Ammonia; Arginase; Arginine; Asparagine; Carboxylic Acids; Enzyme Repression; Glucose; Lactates; Nitrogen; Saccharomyces cerevisiae; Serine; Time Factors; Urea | 1974 |
Hemoglobin 3 chains in apes. Primary structures and the presumptive nature of back mutation in a normally silent gene.
Topics: Alleles; Amino Acid Sequence; Amino Acids; Animals; Asparagine; Aspartic Acid; Chromosome Mapping; Computers; Cross Reactions; Genes; Genetic Code; Hemoglobins; Hominidae; Immunodiffusion; Male; Mutation; Pan troglodytes; Peptides; Rabbits; Serine; Species Specificity; Suppression, Genetic; Tritium; Trypsin | 1973 |
Carboxyl group modification and amide assignments in automated sequencing of proteins.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Chemical Phenomena; Chemistry; Esters; Glutamates; Glutamine; Glycine; Hydrolysis; Imines; Methanol; Methods; Methylamines; Ribonucleases; Serine; Thiazoles | 1972 |
Amino acids and peptides. 34. Synthesis of a structure related to scotophobin.
Topics: Alanine; Amino Acid Sequence; Asparagine; Aspartic Acid; Glutamine; Glycine; Lysine; Memory; Peptides; Serine; Tyrosine | 1972 |
[Amino acid metabolism pathology in the convulsive syndrome in young children].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Child, Preschool; Cystine; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Infant; Infant, Newborn; Leucine; Lysine; Male; Methionine; Proline; Seizures; Serine; Tryptophan; Tyrosine; Valine | 1972 |
Effect of D-alanine and D-aspartic acid on the chick.
Topics: Alanine; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Asparagine; Aspartic Acid; Body Weight; Chickens; Diet; Dietary Proteins; Dose-Response Relationship, Drug; Drug Synergism; Glutamates; Glycine max; Growth; Plant Proteins; Serine; Stereoisomerism; Structure-Activity Relationship; Vitamins | 1972 |
[Demonstration of tumor-induced amino acid changes in the extracellular fluid using two-way separation by high voltage electrophoresis followed by chromatography].
Topics: Amino Acids; Aminobutyrates; Animals; Asparagine; Aspartic Acid; Chromatography; Cystine; Electrophoresis; Extracellular Space; Glutamates; Glutamine; Rats; Sarcoma, Yoshida; Serine; Threonine | 1972 |
Concentration of alpha-amino nitrogen and free amino acid in the uterine and blastocoelic fluid of rabbit.
Topics: Alanine; Amines; Amino Acids; Amniotic Fluid; Animals; Asparagine; Autoanalysis; Blastocyst; Castration; Chromatography, Paper; Embryo Implantation; Estrus; Female; Fertilization; Glutamates; Glutamine; Glycine; Nitrogen; Pregnancy; Pregnancy, Animal; Rabbits; Serine; Time Factors | 1972 |
Effect of pentobarbital on amino acid and urea flux in the isolated dog brain.
Topics: Amino Acids; Anesthesia, General; Animals; Asparagine; Aspartic Acid; Brain; Cerebrovascular Circulation; Dipeptides; Dogs; Glutamates; Glutamine; Glycine; Halothane; Isoleucine; Leucine; Methoxyflurane; Nitrogen; Pentobarbital; Proline; Serine; Taurine; Urea; Valine | 1973 |
Amino acid levels in plasma, liver, and skeletal muscle during protein deprivation.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Body Weight; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Liver; Male; Methionine; Muscles; Organ Size; Phenylalanine; Protein Deficiency; Rats; Serine; Threonine; Time Factors; Tyrosine; Valine | 1973 |
Carbon 13 nuclear magnetic resonance of pentapeptides of glycine containing central residues of serine, threonine, aspartic and glutamic acids, asparagine, and glutamine.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry; Computers; Fourier Analysis; Glutamates; Glutamine; Glycine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mathematics; Oligopeptides; Protons; Serine; Threonine; Time Factors | 1973 |
Influence of denervation on the free amino acids of the rat diaphragm.
Topics: Alanine; Amino Acids; Animals; Asparagine; Denervation; Diaphragm; Glutamine; Glycine; Liver Regeneration; Male; Rats; Serine; Taurine; Time Factors | 1973 |
Theoretical conformational analysis of methylamides of N-acetyl-L-serine and N-acetyl-L-asparagine.
Topics: Amides; Asparagine; Carboxypeptidases; Chemical Phenomena; Chemistry; Chymotrypsin; Lactalbumin; Models, Structural; Molecular Conformation; Muramidase; Myoglobin; Optical Rotation; Peptides; Ribonucleases; Serine; Spectrophotometry, Infrared | 1973 |
Evolution of glycoproteins as judged by the frequency of occurrence of the tripeptides Asn-X-Ser and Asn-X-Thr in proteins.
Topics: Amino Acid Sequence; Animals; Asparagine; Biological Evolution; Glycoproteins; Oligopeptides; Peptide Fragments; Serine; Threonine | 1973 |
Intracellular free amino acid concentration in human muscle tissue.
Topics: Adult; Alanine; Amino Acids; Arginine; Asparagine; Biopsy, Needle; Body Water; Chlorides; Citrulline; Extracellular Space; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Muscles; Ornithine; Phenylalanine; Proline; Serine; Taurine; Tyrosine; Valine | 1974 |
A method for isolation of abnormal haemoglobins with high oxygen affinity due to a frozen quaternary r-structure: application to Hb Creteil alpha 2 A beta 2 (F5) 89 ASN.
Topics: Amino Acids; Asparagine; Binding Sites; Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cystamine; Electrophoresis; Female; France; Hemoglobins, Abnormal; Humans; Iodoacetates; Methods; Oxygen; Oxyhemoglobins; Pedigree; Peptide Fragments; Protein Binding; Protein Conformation; Serine; Trypsin; Urea | 1974 |
Altered amino acid concentrations accompanying suppression of malignancy of mouse melanoma cells by 5-bromodeoxyuridine.
Topics: Alanine; Amino Acids; Animals; Asparagine; Bromodeoxyuridine; Cells, Cultured; Glutamates; Glutamine; Glycine; Lysine; Melanoma; Methionine; Mice; Neoplasm Proteins; Ornithine; Phenylalanine; Pigmentation; Proline; Serine; Threonine; Valine | 1974 |
A simple method for large-scale preparation of chick embryo tRNA.
Topics: Alanine; Animals; Asparagine; Carbon Radioisotopes; Chick Embryo; Chromatography, DEAE-Cellulose; Chromatography, Gel; Evaluation Studies as Topic; Glycine; Hydrogen-Ion Concentration; Methods; RNA, Transfer; Serine; Threonine; Time Factors; Valine | 1974 |
Highly restricted specificity of the serine proteinase aspergillopeptidase B.
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Aspergillus; Cattle; Chromatography, Ion Exchange; Evaluation Studies as Topic; Glutamates; Hydrogen-Ion Concentration; Insulin; Kinetics; Leucine; Methods; Oxidation-Reduction; Peptide Fragments; Peptide Hydrolases; Serine; Spectrophotometry, Ultraviolet; Time Factors; Tyrosine; Zinc | 1974 |
Suppressor selectrion for amino acid replacements expected on the basis of the genetic code.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bacterial Proteins; Escherichia coli; Genes; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Histidine; Hydro-Lyases; Isoleucine; Leucine; Lysine; Methionine; Mutation; Nucleotides; Phenylalanine; RNA, Messenger; Serine; Suppression, Genetic; Threonine; Tyrosine; Valine | 1967 |
Formaldehyde-induced cross-linkages in the subunit of the Escherichia coli tryptophan synthetase.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Paper; Chymotrypsin; Electrophoresis; Electrophoresis, Disc; Escherichia coli; Formaldehyde; Glutamine; Glycerophosphates; Hydro-Lyases; Indoles; Kinetics; Lysine; Molecular Weight; Paper; Pepsin A; Peptides; Serine; Trypsin; Tryptophan | 1971 |
D-Alanine-D-glutamate transaminase. I. Purification and characterization.
Topics: Alanine; Aminobutyrates; Apatites; Asparagine; Aspartic Acid; Bacillus subtilis; Chemical Phenomena; Chemistry; Chromatography; Dextrans; Electrophoresis; Glutamates; In Vitro Techniques; Methionine; Ornithine; Pyridoxine; Serine; Transaminases; Ultracentrifugation | 1965 |
"Dysgonic" strains of mycobacterium tuberculosis on Ogawa's egg medium isolated as pathogens from patients suffering from lung tuberculosis. II. Growth-inhibitory effects of D-asparagine, D-aspartic acid, Dl-serine, or L-serine against "dysgonic".
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Culture Media; Depression, Chemical; Glutamine; Histidine; Humans; Leucine; Mycobacterium tuberculosis; Proline; Serine; Tuberculosis, Pulmonary; Valine | 1967 |
Cyanide metabolism by Bacillus megaterium.
Topics: Amino Acids; Asparagine; Aspartic Acid; Bacillus megaterium; Carbon Dioxide; Carbon Isotopes; Cell-Free System; Chromatography, Paper; Culture Media; Cyanides; Electrophoresis; Models, Biological; Paper; Radioisotopes; Serine; Soil Microbiology | 1969 |
The N-terminal structure of adult hemoglobin from Japanese monkey (Macaca fuscata fuscata) and the N-terminal amino acids of all the tryptic peptides from its alpha and beta polypeptide chains.
Topics: Amino Acids; Animals; Asparagine; Chromatography, Paper; Countercurrent Distribution; Globins; Haplorhini; Heme; Hemoglobins; Humans; Peptides; Serine; Spectrophotometry; Time Factors; Trypsin | 1969 |
Human pancreatic enzymes. Isolation and properties of a major form of chymotrypsin.
Topics: Acetone; Amino Acids; Animals; Asparagine; Butanones; Calcium Chloride; Cattle; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Cysteine; Electrophoresis, Disc; Humans; Hydrogen-Ion Concentration; Immunodiffusion; Isoflurophate; Isoleucine; Molecular Weight; Pancreas; Quaternary Ammonium Compounds; Rabbits; Serine; Species Specificity; Spectrophotometry; Sulfates; Trypsin; Ultracentrifugation; Ultraviolet Rays | 1971 |
Studies on the carbohydrate units of thyroglobulin. Evaluation of their microheterogeneity in the human and calf proteins.
Topics: Animals; Asparagine; Carbohydrates; Cattle; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Fucose; Galactose; Glucosamine; Glycopeptides; Hexosamines; Humans; Hydrogen-Ion Concentration; Mannose; Neuraminic Acids; Oligosaccharides; Pronase; Serine; Species Specificity; Sulfites; Threonine; Thyroglobulin | 1972 |
Concentration gradients of amino acids between the uterine and blastocoelic fluid in the rabbit.
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Body Fluids; Female; Glutamates; Glycine; Male; Methionine; Methods; Ovum; Pregnancy; Rabbits; Serine; Taurine; Uterus | 1972 |
Crystal structure of a subtilisin BPN' complex with N-benzoyl-L-arginine.
Topics: Amides; Arginine; Asparagine; Bacillus; Benzoates; Binding Sites; Carboxylic Acids; Crystallography; Esters; Guanidines; Ketones; Models, Structural; Peptide Biosynthesis; Peptide Chain Elongation, Translational; Peptide Hydrolases; Protease Inhibitors; Protein Conformation; Serine; Tyrosine; X-Ray Diffraction | 1972 |
Influence of nutrition on the morphology of a strain of Bifidobacterium bifidum.
Topics: Acetates; Alanine; Amino Acids; Asparagine; Aspartic Acid; Culture Media; Cysteine; Glutamates; Lactobacillus; Mutation; Nutritional Physiological Phenomena; Quaternary Ammonium Compounds; Serine; Surface-Active Agents; Tryptophan | 1972 |
Oxygen equilibrium characteristics of abnormal hemoglobins. Hirose (alpha-2-beta-2-37Ser), L Ferrara (alpha-2-47-Gly-beta-2), Broussais (alpha-2-90-Asn-beta-2), and Dhofar (alpha-2-beta-2-58Arg).
Topics: Arginine; Asparagine; Aspartic Acid; Electrophoresis, Starch Gel; Genetic Variation; Glycine; Hemoglobins, Abnormal; Heterozygote; Humans; Hydrogen-Ion Concentration; Lysine; Macromolecular Substances; Mathematics; Oxygen; Partial Pressure; Polarography; Proline; Serine; Tryptophan | 1972 |
Serum aminotransferase activities and plasma free amino acid concentration as criteria for pyridoxine nutritional status of chicks.
Topics: Alanine Transaminase; Amino Acids; Aminobutyrates; Ammonia; Animal Nutritional Physiological Phenomena; Animals; Asparagine; Aspartate Aminotransferases; Body Weight; Chickens; Cysteine; Diet; Feeding Behavior; Glutamine; Glycine; Male; Ornithine; Pyridoxal Phosphate; Pyridoxine; Serine; Taurine; Vitamin B 6 Deficiency | 1972 |
Effect of substrate structure on coupling ratio for Na + -dependent transport of amino acids.
Topics: Alanine; Amino Acids; Animals; Asparagine; Biological Transport; Carbon Isotopes; Columbidae; Cysteine; Erythrocytes; Hydroxyproline; Kinetics; Models, Biological; Models, Structural; Potassium; Potassium Isotopes; Proline; Serine; Sodium; Sodium Chloride; Sodium Isotopes; Structure-Activity Relationship; Threonine; Tritium | 1971 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Serine requirement in leukemic and normal blood cells.
Topics: Alanine; Asparagine; Aspartic Acid; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Culture Media; DNA, Neoplasm; Fibroblasts; Glucose; Glutamates; Glycine; Humans; In Vitro Techniques; Leukemia, Myeloid; Neoplasm Proteins; Proline; RNA, Neoplasm; Serine; Thymidine; Tritium; Uridine | 1969 |
[Deamination of amino acids by resting cells of Streptococcus mitis].
Topics: Amino Acids; Arginine; Asparagine; Serine; Streptococcus | 1969 |
Degeneracy in the amino acid code.
Topics: Amino Acids; Asparagine; Bacterial Proteins; Escherichia coli; Genetic Code; Glutamine; Histidine; Leucine; Lysine; Polynucleotides; Proline; Serine; Threonine | 1966 |
A lithium buffer system for single-column amino acid analysis.
Topics: Amino Acids; Asparagine; Autoanalysis; Buffers; Chromatography, Ion Exchange; Citrates; Glutamine; Hot Temperature; Indicators and Reagents; Lithium; Serine; Threonine | 1969 |
[On the capability of the members of the genus Aeromonas to use amino acids as sole source of carbon].
Topics: Aeromonas; Alanine; Amino Acids; Arginine; Asparagine; Culture Media; Glutamates; Histidine; Leucine; Methionine; Phenylalanine; Serine; Species Specificity | 1969 |
The importance of dispensable amino acids for maximal growth in the rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Body Weight; Citrates; Diet; Glutamates; Glycine; Growth; Male; Nutritional Requirements; Proline; Rats; Serine | 1970 |
Prediction and explanation of chemical mutation sites.
Topics: Arginine; Asparagine; Genetic Code; Genetics, Microbial; Glycine; Leucine; Models, Chemical; Mutagens; Mutation; Nucleotides; Phenylalanine; Proline; RNA, Viral; Serine; Tobacco Mosaic Virus | 1970 |
Circadian ythm of human urinary amino acid excretion in fed and fasted states.
Topics: 17-Hydroxycorticosteroids; Adult; Alanine; Amino Acids; Asparagine; Circadian Rhythm; Cystinuria; Fasting; Feeding Behavior; Glutamates; Glutamine; Glycine; Humans; Male; Middle Aged; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1970 |
The amino acid sequence of the beta-chains of rabbit hemoglobin.
Topics: Amino Acid Sequence; Animals; Asparagine; Chromatography, Ion Exchange; Chymotrypsin; Hemoglobins; Histidine; Leucyl Aminopeptidase; Peptides; Rabbits; Serine; Trypsin | 1970 |
The occurrence in proteins of the tripeptides Asn-X-Ser and Asn-X-Thr and of bound carbohydrate.
Topics: Amino Acid Sequence; Asparagine; Carbohydrates; Computers; Glycoproteins; Peptides; Proteins; Serine; Statistics as Topic; Threonine | 1970 |
A new hypothesis on the evolution of the genetic code.
Topics: Amino Acids; Arginine; Asparagine; Biological Evolution; Cysteine; Genetic Code; Glutamine; Leucine; Lysine; Methionine; Models, Chemical; Models, Structural; Nucleotides; Proline; Serine; Threonine; Tyrosine | 1970 |
[Effect of amino acids on the growth of Streptococcus lactis and biosynthesis of nisin].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Depression, Chemical; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Stimulation, Chemical; Streptococcus; Threonine; Tryptophan; Valine | 1970 |
[Amino acid composition of calf skin proteins and radiation effects].
Topics: Amino Acids; Animals; Arginine; Asparagine; Cattle; Chromatography, Paper; Cystine; Glutamine; Glycine; Histidine; Proteins; Radiation Effects; Serine; Skin | 1970 |
Rabbit hemoglobin. The heterogeneity of the beta-chain.
Topics: Acetates; Alleles; Amino Acids; Animals; Asparagine; Chromatography, Ion Exchange; Formates; Glutamine; Hemoglobins; Heterozygote; Histidine; Homozygote; Peptides; Pyridines; Rabbits; Serine | 1971 |
Metabolism of amino acids in plants. I. Changes in the soluble amino acid fractions of bushbean seedlings (Phaseolus vulgaris L.) and the development of transaminase activity.
Topics: Alanine; Alanine Transaminase; Amino Acids; Asparagine; Aspartate Aminotransferases; Cadmium; Chromatography, Paper; Colorimetry; Darkness; Indenes; Ketones; Light; Nitrogen; Plant Development; Plant Physiological Phenomena; Plant Proteins; Plants; Radiation Effects; Seeds; Serine; Solubility; Threonine; Time Factors; Transaminases; Trichloroacetic Acid; Valine | 1971 |
[Free amino acids and other ninhydrin-positive substances in the normal horny layer and in psoriasis scales].
Topics: Alanine; Amino Acids; Ammonia; Asparagine; Chromatography; Citrulline; Cysteine; Glycine; Histidine; Humans; Imidazoles; Phenylalanine; Proline; Psoriasis; Serine; Skin; Taurine; Threonine; Urea | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Biosynthesis of bacitracin. II. Incorporation of 14C-labeled amino acids into bacitracin by a cell-free preparation from Bacillus licheniformis.
Topics: Adenosine Triphosphate; Amino Acids; Asparagine; Bacillus; Bacitracin; Bacteriolysis; Carbon Isotopes; Cell-Free System; Chloramphenicol; Chromatography, Paper; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Magnesium; Ornithine; Peptide Biosynthesis; Phenylalanine; Puromycin; Ribonucleases; Serine; Time Factors | 1968 |
Incorporation of serine-U-14C into beta-cyanoalanine and gamma-glutamyl-beta-cyanoalanine in Vicia sativa.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; Glutamates; Nitriles; Peptide Biosynthesis; Plant Development; Plants; Seeds; Serine | 1968 |
Naturally occurring low-molecular-weight peptides from the blowfly Phormia regina.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Dipeptides; Diptera; Glutamine; Glycine; Isoleucine; Lysine; Peptides; Serine; Valine | 1968 |
[On the influence of the starting position on migration of substances in paper electrophoresis].
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Asparagine; Cysteine; Electrophoresis; Glucose; Glutamates; Glutamine; Glycine; Histidine; Leucine; Lysine; Methionine; Serine; Serum Albumin; Taurine; Tryptophan | 1968 |
[The free amino acids in a water-soluble superficial film of the skin in exanthematous diseases in childhood].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chickenpox; Child; Chromatography, Paper; Female; Glutamine; Glycine; Histidine; Humans; Leucine; Male; Measles; Rubella; Scarlet Fever; Serine; Sweat; Valine | 1968 |
[Incorporation of 14C-proline into ripening wheat].
Topics: Asparagine; Carbon Isotopes; Chromatography, Thin Layer; Glycine; Peptides; Plant Proteins; Proline; Serine; Threonine; Triticum | 1968 |
The antidiuretic hormone blocking effect of some oxytocin analogues.
Topics: Amino Acid Sequence; Animals; Asparagine; Diuresis; Isoleucine; Kidney; Male; Oxytocin; Rats; Serine; Vasopressins; Water | 1968 |
[Growth of Propionibacterium shermanii with single amino acids as nitrogen source].
Topics: Amino Acids; Asparagine; Culture Media; Oxygen; Propionibacterium; Quaternary Ammonium Compounds; Serine; Urea | 1968 |
[Crystalline leucine aminopeptidase from bovine lens. Amino acid composition and N-terminal amino acids, II].
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Cattle; Crystallography; Formates; Glutamates; Glutamine; Glycine; Lens, Crystalline; Leucine; Leucyl Aminopeptidase; Lysine; Serine; Threonine | 1968 |
Beta-cyanoalanine formation by Chromobacterium violaceum.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; Carbon Isotopes; Chromobacterium; Cyanides; Formaldehyde; Glycine; Methionine; Serine; Succinates | 1969 |
The glycoprotein structure of yeast invertase.
Topics: Amino Acids; Asparagine; Carbohydrates; Cell Wall; Chemical Phenomena; Chemistry; Chromatography, Gel; Dextrans; Glucosamine; Glycoproteins; Glycoside Hydrolases; Hydrazines; Hydrogen-Ion Concentration; Oligosaccharides; Peptide Hydrolases; Peptides; Polysaccharides; Saccharomyces; Serine; Streptomyces; Sucrase; Threonine | 1969 |
Water relations of Salmonella oranienburg; stimulation of respiration by amino acids.
Topics: Alanine; Asparagine; Aspartic Acid; Carbon Isotopes; Culture Media; Cysteine; Glucose; Glutamine; Glycine; Methionine; Oxygen Consumption; Proline; Salmonella; Serine; Threonine; Water | 1966 |
[The influence of temperature on the content of some carbohydrates and amino acids in Spirogyra].
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Carbohydrate Metabolism; Chromatography, Paper; Eukaryota; Fructose; Glucose; Glutamates; Glutamine; Leucine; Nitrogen; Serine; Starch; Temperature; Valine | 1966 |
[Chromatographic investigation of free amino acids of the heart, kidneys and brain in experimental myocarditis].
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Brain; Chromatography, Paper; Cystine; Glutamine; Glycine; Histidine; Kidney; Lysine; Methionine; Myocarditis; Myocardium; Phenylalanine; Rabbits; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
The occurrence of hypotaurine and other sulfur-containing amino acids in seminal plasma and spermatozoa of boar, bull and dog.
Topics: Alanine; Amino Acids; Animals; Asparagine; Cattle; Dogs; Electrophoresis; Glutamates; Glycine; In Vitro Techniques; Leucine; Male; Semen; Serine; Spermatozoa; Swine; Taurine; Valine | 1966 |
A new developing solvent for paper chromatography of various phenolic compounds, sugars and amino acids.
Topics: Amino Acids; Anthocyanins; Arginine; Asparagine; Carbohydrates; Chromatography, Paper; Gallic Acid; Glutamates; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Phenols; Phenylalanine; Phloroglucinol; Proline; Resorcinols; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Reactions in frozen systems. VI. Ice as a possible model for biological structured-water systems.
Topics: Acetylcholine; Asparagine; Catalysis; Chemical Phenomena; Chemistry; Copper; Cytosine; Dioxins; Glutamates; Glutamine; Glycine; Hydroxylamines; Ice; Imidazoles; Kinetics; Models, Theoretical; Nitrates; Phenylalanine; Piperazines; Potassium Chloride; Pyrazoles; Serine; Tyrosine | 1967 |
The influence of medium composition on the growth and swarming of Proteus.
Topics: Alanine; Asparagine; Aspartic Acid; Culture Media; Glutamates; Glutamine; Proline; Proteus; Serine | 1967 |
Urinary amino acids of rats receiving high sugar diets.
Topics: Alanine; Alcohols; Amino Acids; Animals; Arabinose; Ascorbic Acid; Asparagine; Aspartic Acid; Dietary Carbohydrates; Female; Galactose; Glucose; Glutamates; Glycine; Inositol; Intestines; Neomycin; Rats; Ribose; Serine; Taurine; Threonine; Xylitol; Xylose | 1967 |
Requirements for growth of Streptococcus agalactiae in a chemically defined medium.
Topics: Alanine; Ascorbic Acid; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Proline; Serine; Streptococcus; Thioglycolates | 1967 |
The influence of nitrogenous compounds on growth of Pythium species.
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Cysteine; Fungi; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Nitrates; Nitrites; Nitrogen; Peptones; Quaternary Ammonium Compounds; Serine; Succinates; Threonine; Yeast, Dried | 1967 |
Oligosaccharide branching of glycoproteins: biosynthetic mechanisms and possible biological functions.
Topics: Animals; Asparagine; Carbohydrate Sequence; Glycoproteins; Hexosyltransferases; Mucins; Oligosaccharides; Protein Processing, Post-Translational; Serine; Swine; Threonine | 1982 |
Synthesis and possible role of carbohydrate moieties of yeast glycoproteins.
Topics: Asparagine; Biological Transport; Dolichol Phosphates; Endoplasmic Reticulum; Fungal Proteins; Glycoproteins; Liposomes; Mannose; Oligosaccharides; Polyisoprenyl Phosphates; Serine; Threonine | 1982 |
Purification and properties of an asparagine aminotransferase from Pisum sativum leaves.
Topics: Asparagine; Fabaceae; Glyoxylates; Hydrogen-Ion Concentration; Plants, Medicinal; Pyridoxal Phosphate; Serine; Substrate Specificity; Transaminases | 1983 |
Substrate recognition by oligosaccharyltransferase. Studies on glycosylation of modified Asn-X-Thr/Ser tripeptides.
Topics: Animals; Asparagine; Chickens; Female; Glycopeptides; Hexosyltransferases; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Membrane Proteins; Microsomes; Oligopeptides; Oviducts; Serine; Substrate Specificity; Threonine; Transferases | 1983 |
Model studies on N-glycosylation of proteins.
Topics: Amino Acid Sequence; Animals; Asparagine; Carbohydrate Metabolism; Hydrogen; Models, Chemical; Proteins; Serine; Threonine | 1984 |
Circular dichroism studies of synthetic Asn-X-Ser/Thr-containing peptides: Structure-glycosylation relationship.
Topics: Amino Acid Sequence; Animals; Asparagine; Cell Membrane; Chickens; Circular Dichroism; Female; Glycopeptides; In Vitro Techniques; Oviducts; Peptides; Serine; Structure-Activity Relationship; Threonine | 1981 |
The structure of hemoglobin Creteil (beta 89 Ser replaced by Asn) is similar to that of abnormal human hemoglobins having sequence changes at Tyr 145 beta.
Topics: Amino Acid Sequence; Asparagine; Hemoglobins, Abnormal; Heterozygote; Humans; Models, Molecular; Protein Conformation; Serine; Spectrophotometry; Tyrosine; X-Ray Diffraction | 1981 |
Methods for the identification of N-asparaginyl and O-seryl/threonyl glycosidic linkages to aminosugars in glycoproteins.
Topics: Asparagine; Borohydrides; Carbohydrate Sequence; Dansyl Compounds; Electrophoresis; Glycoproteins; Hydrolysis; Methods; Mucins; Ovalbumin; Serine; Threonine | 1981 |
Effect of non-essential amino acids on fetal rat pancreatic growth and insulin secretion in vitro.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Glycine; Insulin; Insulin Secretion; Organ Culture Techniques; Pancreas; Proline; Rats; Rats, Inbred Strains; Serine | 1981 |
Effect of dimethylsulfoxide on two synthetic Asn-X-Thr containing substrates of the oligosaccharyltransferase.
Topics: Animals; Asparagine; Carbohydrate Conformation; Circular Dichroism; Dimethyl Sulfoxide; Hexosyltransferases; Kinetics; Membrane Proteins; Microsomes; Serine; Substrate Specificity; Swine; Thyroid Gland; Transferases | 1982 |
Mutations in the elongation factor 2 gene which confer resistance to diphtheria toxin and Pseudomonas exotoxin A. Genetic and biochemical analyses.
Topics: ADP Ribose Transferases; Amino Acid Sequence; Animals; Asparagine; Bacterial Toxins; Base Sequence; CHO Cells; Cricetinae; Diphtheria Toxin; Drug Resistance; Exotoxins; Glycine; Histidine; Humans; Isoleucine; Molecular Sequence Data; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphoproteins; Plasmids; Point Mutation; Polymorphism, Restriction Fragment Length; Protein Synthesis Inhibitors; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Recombinant Proteins; Restriction Mapping; Sequence Homology, Amino Acid; Serine; Transfection; Virulence Factors | 1995 |
The mutation Asp69-->Ser affects the chaperone-like activity of alpha A-crystallin.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Chromatography, Gel; Crystallins; DNA Mutational Analysis; Escherichia coli; Fluorescence; Hot Temperature; Molecular Chaperones; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Folding; Serine; Structure-Activity Relationship; Surface Properties | 1995 |
Partial glycosylation of antithrombin III asparagine-135 is caused by the serine in the third position of its N-glycosylation consensus sequence and is responsible for production of the beta-antithrombin III isoform with enhanced heparin affinity.
Topics: Amino Acid Sequence; Animals; Antithrombin III; Asparagine; Baculoviridae; Base Sequence; Binding Sites; Cloning, Molecular; Consensus Sequence; DNA Primers; Gene Expression; Glycosylation; Heparin; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Recombinant Proteins; Restriction Mapping; Serine; Spodoptera; Transfection | 1995 |
Molecular study of the 5 alpha-reductase type 2 gene in three European families with 5 alpha-reductase deficiency.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adolescent; Amino Acid Sequence; Arginine; Asparagine; Base Sequence; Disorders of Sex Development; Exons; Female; France; Glutamine; Histidine; Humans; Introns; Male; Molecular Sequence Data; Open Reading Frames; Point Mutation; Poland; Serine | 1995 |
Asn-265 of frog kainate binding protein is a functional glycosylation site: implications for the transmembrane topology of glutamate receptors.
Topics: Amino Acid Sequence; Animals; Asparagine; Base Sequence; Cell Line; Cell Membrane; Glycosylation; Hexosaminidases; Humans; Kainic Acid; Microsomes; Molecular Sequence Data; Mutation; Ranidae; Receptors, Kainic Acid; Recombinant Proteins; Serine | 1995 |
Trypsin complexed with alpha 1-proteinase inhibitor has an increased structural flexibility.
Topics: alpha 1-Antitrypsin; Amino Acid Sequence; Animals; Asparagine; Cattle; Chromatography; Electrophoresis, Polyacrylamide Gel; Humans; Molecular Sequence Data; Mutation; Protein Conformation; Rats; Serine; Trypsin | 1995 |
Two new immunogenetic polymorphisms of the apoB gene and their effect on serum lipid levels and responses to changes in dietary fat intake.
Topics: Alleles; Apolipoproteins B; Asparagine; Base Sequence; Dietary Fats; Female; Finland; Gene Frequency; Genetic Variation; Genotype; Humans; Lipids; Male; Molecular Sequence Data; Pedigree; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Serine | 1995 |
Crystallographic and enzymatic investigations on the role of Ser558, His610, and Asn614 in the catalytic mechanism of Azotobacter vinelandii dihydrolipoamide acetyltransferase (E2p).
Topics: Acetyltransferases; Amino Acid Sequence; Asparagine; Azotobacter vinelandii; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Dihydrolipoyllysine-Residue Acetyltransferase; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyruvate Dehydrogenase Complex; Serine; Structure-Activity Relationship | 1995 |
Site-directed mutagenesis of the alpha subunit of human prolyl 4-hydroxylase. Identification of three histidine residues critical for catalytic activity.
Topics: Animals; Asparagine; Catalysis; Cell Line; Glutamine; Histidine; Humans; Mutagenesis, Site-Directed; Nucleopolyhedroviruses; Procollagen-Proline Dioxygenase; Serine; Spodoptera | 1995 |
Human beta-cell glucokinase. Dual role of Ser-151 in catalysis and hexose affinity.
Topics: Acetylglucosamine; Adenosine Triphosphatases; Asparagine; Base Sequence; Catalysis; Circular Dichroism; Fluorescence; Glucokinase; Glucose-6-Phosphate; Glucosephosphates; Hexokinase; Humans; Islets of Langerhans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphorylation; Serine; Substrate Specificity | 1995 |
Sequence of a segment of yeast chromosome II shows two novel genes, one almost entirely hydrophobic and the other extremely asparagine-serine rich.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Chromosome Mapping; Chromosomes, Fungal; Deoxyribonuclease EcoRI; DNA, Fungal; Fungal Proteins; Genes, Fungal; Membrane Proteins; Molecular Sequence Data; Open Reading Frames; Restriction Mapping; Saccharomyces cerevisiae; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serine; TATA Box | 1994 |
Low nidogen affinity of laminin-5 can be attributed to two serine residues in EGF-like motif gamma 2III4.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Basement Membrane; Binding Sites; Cell Adhesion Molecules; Cell Line; DNA Primers; Epidermal Growth Factor; Humans; Kalinin; Kinetics; Membrane Glycoproteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Transfection; Valine | 1995 |
Biological activity of human N-ras and K-ras genes containing the Asn17 dominant negative mutation.
Topics: 3T3 Cells; Alleles; Amino Acid Sequence; Animals; Asparagine; Cell Line, Transformed; Codon; Colony-Forming Units Assay; Genes, Dominant; Genes, ras; Genetic Complementation Test; Humans; Mice; Molecular Sequence Data; Oncogene Proteins v-raf; Plasmids; Point Mutation; Promoter Regions, Genetic; Proto-Oncogene Proteins p21(ras); Recombinant Fusion Proteins; Retroviridae Proteins, Oncogenic; Serine; Signal Transduction; Transfection | 1994 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
Circadian variations of amino acid content of suprachiasmatic nucleus in rats.
Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Circadian Rhythm; Glycine; Light; Male; Rats; Rats, Wistar; Serine; Suprachiasmatic Nucleus | 1994 |
Two mutant alleles of the insulin receptor gene in a family with a genetic form of insulin resistance: a 10 base pair deletion in exon 1 and a mutation substituting serine for asparagine-462.
Topics: Alleles; Amino Acid Sequence; Asparagine; Base Sequence; Exons; Female; Genotype; Humans; Hydrogen-Ion Concentration; Insulin Resistance; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Receptor, Insulin; RNA, Messenger; Sequence Deletion; Serine | 1995 |
Stabilizing and destabilizing effects of placing beta-branched amino acids in protein alpha-helices.
Topics: Acetonitriles; Amino Acids, Branched-Chain; Asparagine; Bacteriophage T4; Base Sequence; Circular Dichroism; Computer Simulation; Drug Stability; Electrophoresis, Polyacrylamide Gel; Leucine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Muramidase; Mutation; Oligonucleotides; Protein Structure, Secondary; Serine; Valine | 1994 |
Liquid chromatographic-mass spectrometric analysis of N-acetylamino acids in human urine.
Topics: Acetylation; Amino Acids; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glutamates; Glutamine; Humans; Lysine; Mass Spectrometry; Regression Analysis; Serine | 1994 |
Inhibition of rat prolactin (PRL) storage by coexpression of human PRL.
Topics: Animals; Asparagine; Biological Transport; Cell Compartmentation; Cytoplasmic Granules; Epidermal Growth Factor; Estradiol; Gene Expression; Humans; Insulin; Models, Molecular; Pituitary Neoplasms; Prolactin; Protein Conformation; Rats; Recombinant Fusion Proteins; Serine; Species Specificity; Transfection; Tumor Cells, Cultured | 1994 |
A naturally occurring mutation at the second base of codon asparagine 43 in the proposed N-linked glycosylation site of human lipoprotein lipase: in vivo evidence that asparagine 43 is essential for catalysis and secretion.
Topics: Adult; Amino Acid Sequence; Asparagine; Base Sequence; Codon; DNA Mutational Analysis; DNA, Complementary; Glycosylation; Heparin; Humans; Lipoprotein Lipase; Male; Molecular Sequence Data; Mutation; Serine | 1994 |
Variant Bernard-Soulier syndrome associated with a homozygous mutation in the leucine-rich domain of glycoprotein IX.
Topics: Adult; Amino Acid Sequence; Asparagine; Base Sequence; Bernard-Soulier Syndrome; Blood Platelets; Blotting, Western; DNA; DNA Primers; Female; Genetic Variation; Humans; Leucine; Male; Molecular Sequence Data; Pedigree; Platelet Aggregation; Platelet Membrane Glycoproteins; Point Mutation; Polymerase Chain Reaction; Reference Values; Serine | 1994 |
An evaluation of the role of extracellular amino acids in the delayed neurodegeneration induced by quinolinic acid in the rat striatum.
Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Corpus Striatum; Dialysis; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Male; Microinjections; Nerve Degeneration; Niacin; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Serine; Threonine | 1993 |
A new investigation of copper(II)-serine, copper(II)-histidine-serine, copper(II)-asparagine, and copper(II)-histidine-asparagine equilibria under physiological conditions, and implications for simulation models relative to blood plasma.
Topics: Asparagine; Computer Simulation; Copper; Histidine; Kinetics; Models, Biological; Models, Chemical; Serine | 1993 |
HLA-C is the inhibitory ligand that determines dominant resistance to lysis by NK1- and NK2-specific natural killer cells.
Topics: Alleles; Amino Acid Sequence; Asparagine; B-Lymphocytes; Cell Line; Cell Line, Transformed; Cytotoxicity, Immunologic; Gene Deletion; Genes, MHC Class I; Herpesvirus 4, Human; HLA-C Antigens; Homozygote; Humans; Isoantigens; Killer Cells, Natural; Lymphocyte Culture Test, Mixed; Major Histocompatibility Complex; Point Mutation; Serine; Transfection | 1993 |
PPQ, a novel protein phosphatase containing a Ser + Asn-rich amino-terminal domain, is involved in the regulation of protein synthesis.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Chromosome Mapping; Chromosomes, Fungal; DNA, Fungal; Fungal Proteins; Molecular Sequence Data; Phosphoprotein Phosphatases; Protein Synthesis Inhibitors; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Serine | 1993 |
A structure/activity study of calcium affinity and selectivity using a synthetic peptide model of the helix-loop-helix calcium-binding motif.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Calcium; Calmodulin; Helix-Loop-Helix Motifs; Kinetics; Magnesium; Models, Structural; Molecular Sequence Data; Peptides; Protein Conformation; Protein Structure, Secondary; Serine; Structure-Activity Relationship | 1994 |
Glycosylation of two recombinant human uterine tissue plasminogen activator variants carrying an additional N-glycosylation site in the epidermal-growth-factor-like domain.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Female; Genetic Variation; Glycine; Glycopeptides; Glycosylation; Humans; Mass Spectrometry; Methylation; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oligosaccharides; Peptide Mapping; Protein Processing, Post-Translational; Recombinant Proteins; Serine; Tissue Plasminogen Activator; Tyrosine; Uterus | 1994 |
A new kinetic mechanism for the concomitant hydrolysis and transfer reactions catalyzed by bacterial DD-peptidases.
Topics: Acylation; Asparagine; Catalysis; Hydrolysis; Kinetics; Muramoylpentapeptide Carboxypeptidase; Mutagenesis, Site-Directed; Mutation; Serine; Streptomyces | 1993 |
Role of pH in determining the cell-type-specific residual activity of glucocerebrosidase in type 1 Gaucher disease.
Topics: Amino Acid Sequence; Asparagine; Cells, Cultured; Fibroblasts; Gaucher Disease; Genotype; Glucosylceramidase; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Kinetics; Mutation; Reference Values; Serine; Skin | 1993 |
Can the stability of protein mutants be predicted by free energy calculations?
Topics: Asparagine; Computer Simulation; Enzyme Stability; Models, Chemical; Mutation; Proteins; Serine; Subtilisins; Thermodynamics | 1993 |
Pro-major basic protein has three types of sugar chains at the pro-portion.
Topics: Amino Acid Sequence; Animals; Asparagine; Blood Proteins; Cricetinae; Eosinophil Granule Proteins; Glycopeptides; Glycoproteins; Glycosylation; Molecular Sequence Data; Monosaccharides; Peptide Mapping; Protein Precursors; Protein Processing, Post-Translational; Protein Sorting Signals; Ribonucleases; Sequence Analysis; Serine; Serine Endopeptidases; Threonine | 1993 |
Autosomal dominant cone-rod dystrophy associated with mutations in codon 244 (Asn244His) and codon 184 (Tyr184Ser) of the peripherin/RDS gene.
Topics: Adult; Aged; Amino Acid Sequence; Asparagine; Base Sequence; Codon; DNA; Electroretinography; Eye Proteins; Female; Fluorescein Angiography; Histidine; Humans; Intermediate Filament Proteins; Male; Membrane Glycoproteins; Middle Aged; Molecular Sequence Data; Nerve Tissue Proteins; Pedigree; Peripherins; Photoreceptor Cells; Point Mutation; Polymorphism, Single-Stranded Conformational; Retinal Degeneration; Serine; Tyrosine; Visual Fields | 1996 |
A frequently occurring mutation in the lipoprotein lipase gene (Asn291Ser) contributes to the expression of familial combined hyperlipidemia.
Topics: Asparagine; Base Sequence; DNA Primers; Electrophoresis, Polyacrylamide Gel; Humans; Hyperlipidemia, Familial Combined; Lipids; Lipoprotein Lipase; Lipoproteins; Male; Molecular Sequence Data; Point Mutation; Serine | 1995 |
Investigation of the active site of oligosaccharyltransferase from pig liver using synthetic tripeptides as tools.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Catalysis; Chemical Phenomena; Chemistry, Physical; Glycosylation; Hexosyltransferases; Hydrogen Bonding; Hydrogen-Ion Concentration; Liver; Membrane Proteins; Molecular Conformation; Molecular Sequence Data; Peptides; Serine; Structure-Activity Relationship; Substrate Specificity; Swine; Threonine; Transferases | 1995 |
Amino-acid-type-selective triple-resonance experiments.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Calcium-Binding Proteins; Carbon; Carrier Proteins; Cysteine; Glycine; Image Enhancement; Isoleucine; Magnetic Resonance Spectroscopy; Methionine; Microfilament Proteins; Nitrogen; Serine; Valine | 1996 |
Polar residues in the transmembrane domains of the type 1 angiotensin II receptor are required for binding and coupling. Reconstitution of the binding site by co-expression of two deficient mutants.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Asparagine; Base Sequence; Binding Sites; Biphenyl Compounds; Cell Line; Chlorocebus aethiops; CHO Cells; Cricetinae; DNA Primers; Imidazoles; Inositol Phosphates; Kinetics; Losartan; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oligopeptides; Point Mutation; Polymerase Chain Reaction; Rats; Receptors, Angiotensin; Recombinant Proteins; Sequence Deletion; Serine; Tetrazoles; Transfection | 1996 |
Lipoprotein lipase gene polymorphisms: associations with myocardial infarction and lipoprotein levels, the ECTIM study. Etude Cas Témoin sur l'Infarctus du Myocarde.
Topics: Adult; Asparagine; Base Sequence; Case-Control Studies; Deoxyribonuclease HindIII; Deoxyribonucleases, Type II Site-Specific; France; Humans; Linkage Disequilibrium; Lipoprotein Lipase; Lipoproteins; Middle Aged; Molecular Sequence Data; Myocardial Infarction; Northern Ireland; Polymorphism, Genetic; Risk Factors; Serine | 1995 |
The ultrastructure of fibrinogen Caracas II molecules, fibers, and clots.
Topics: Asparagine; Blood Coagulation; Fibrin; Fibrinogen; Fibrinogens, Abnormal; Glycosylation; Humans; Microscopy, Electron; Microscopy, Electron, Scanning; Point Mutation; Reference Values; Serine | 1996 |
Residues near the amino and carboxyl termini of staphylococcal enterotoxin E independently mediate TCR V beta-specific interactions.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Asparagine; Enterotoxins; Epitopes; Histocompatibility Antigens Class II; Humans; Mice; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Protein Binding; Receptors, Antigen, T-Cell, alpha-beta; Serine; Staphylococcus aureus; Superantigens | 1996 |
Effects of 7B2 on the maturation of pro-hormone convertase 2 (PC2) in vitro.
Topics: Animals; Asparagine; Aspartic Acid; Female; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Neuroendocrine Secretory Protein 7B2; Oocytes; Pituitary Hormones; Point Mutation; Polymerase Chain Reaction; Proprotein Convertase 2; Protein Processing, Post-Translational; Recombinant Proteins; Serine; Subtilisins; Xenopus laevis | 1996 |
Changes in the intracellular free amino acid pool in human saphenous vein tissue culture.
Topics: Aged; Alanine; Amino Acids; Asparagine; Aspartic Acid; Culture Techniques; Cytosol; Glutamic Acid; Glutamine; Glycine; Humans; Middle Aged; Proline; Saphenous Vein; Serine; Taurine | 1996 |
Unaccustomed high-mileage vs intensity training-related changes in performance and serum amino acid levels.
Topics: Adult; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cystine; Erythrocyte Count; Exercise Test; Fatigue; Glycine; Hematocrit; Hemoglobins; Humans; Lactates; Leukocyte Count; Lysine; Methionine; Phenylalanine; Physical Endurance; Prospective Studies; Running; Serine; Taurine; Tryptophan; Tyrosine | 1996 |
The mechanism of velocity modulated allosteric regulation in D-3-phosphoglycerate dehydrogenase. Site-directed mutagenesis of effector binding site residues.
Topics: Allosteric Regulation; Asparagine; Binding Sites; Carbohydrate Dehydrogenases; Escherichia coli; Histidine; Kinetics; Mutagenesis, Site-Directed; Mutation; Phosphoglycerate Dehydrogenase; Serine; Stereoisomerism | 1996 |
Myristoylation-dependent and electrostatic interactions exert independent effects on the membrane association of the myristoylated alanine-rich protein kinase C substrate protein in intact cells.
Topics: Acylation; Animals; Asparagine; Aspartic Acid; Binding Sites; Chick Embryo; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Microscopy, Immunoelectron; Mutagenesis; Myristic Acid; Myristic Acids; Myristoylated Alanine-Rich C Kinase Substrate; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Proteins; Recombinant Proteins; Serine; Species Specificity; Static Electricity; Subcellular Fractions | 1996 |
Involvement of Asn-293 in stereospecific agonist recognition and in activation of the beta 2-adrenergic receptor.
Topics: Adenylyl Cyclases; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Alprenolol; Animals; Asparagine; Binding Sites; CHO Cells; Computer Simulation; Cricetinae; Humans; Isoproterenol; Metoprolol; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Propranolol; Receptors, Adrenergic, beta-2; Serine; Signal Transduction; Stereoisomerism | 1996 |
Common genetic variants of lipoprotein lipase that relate to lipid transport in patients with premature coronary artery disease.
Topics: Asparagine; Aspartic Acid; Coronary Artery Disease; Genetic Variation; Humans; Lipid Metabolism; Lipoprotein Lipase; Lipoproteins; Middle Aged; Point Mutation; Serine | 1995 |
Structure-function relationships among wild-type variants of Staphylococcus aureus beta-lactamase: importance of amino acids 128 and 216.
Topics: Alanine; Asparagine; beta-Lactamases; Crystallography, X-Ray; Gene Expression; Genetic Variation; Kinetics; Serine; Staphylococcus aureus; Structure-Activity Relationship; Threonine | 1996 |
Compound heterozygosity for a known and a novel defect in the lipoprotein lipase gene (Asp250-->Asn; Ser251-->Cys) resulting in lipoprotein lipase (LPL) deficiency.
Topics: Adolescent; Asparagine; Aspartic Acid; Cysteine; Denmark; DNA; Heterozygote; Humans; Hyperlipoproteinemia Type I; Hypertriglyceridemia; Lipoprotein Lipase; Male; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Serine | 1996 |
Rheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Asparagine; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; Growth Substances; GTP-Binding Proteins; MAP Kinase Kinase 1; MAP Kinase Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Nerve Growth Factors; Neurites; Neuropeptides; Oncogene Protein p21(ras); PC12 Cells; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Ras Homolog Enriched in Brain Protein; Rats; Recombinant Proteins; Serine; Signal Transduction | 1997 |
The conformational change responsible for AT1 receptor activation is dependent upon two juxtaposed asparagine residues on transmembrane helices III and VII.
Topics: Alanine; Amino Acid Sequence; Angiotensin I; Animals; Asparagine; Cell Line; Humans; Inositol 1,4,5-Trisphosphate; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Rats; Receptors, Angiotensin; Sequence Homology, Amino Acid; Serine; Transfection | 1997 |
Substrate recognition of isocitrate dehydrogenase and 3-isopropylmalate dehydrogenase from Thermus thermophilus HB8.
Topics: 3-Isopropylmalate Dehydrogenase; Alcohol Oxidoreductases; Amino Acid Sequence; Asparagine; Aspartic Acid; Binding Sites; Glutamic Acid; Isocitrate Dehydrogenase; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Serine; Substrate Specificity; Thermus thermophilus | 1997 |
Serine319 and 321 are functional in isocitrate lyase from Escherichia coli.
Topics: Alanine; Asparagine; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression Regulation, Bacterial; Glycine; Histidine; Isocitrate Lyase; Isocitrates; Kinetics; Magnesium; Mutagenesis, Site-Directed; Oligonucleotides; Plasmids; Proline; Sequence Alignment; Serine; Threonine | 1997 |
Comparison of the biological activity of synthetic N-acylated asparagine or serine linked monosaccharide lipid A analogs.
Topics: Acylation; Animals; Antineoplastic Agents; Asparagine; Fibrosarcoma; Lipid A; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mitogens; Monosaccharides; Nitric Oxide; Sarcoma, Experimental; Serine; Tumor Necrosis Factor-alpha | 1996 |
Classification of serine proteases derived from steric comparisons of their active sites, part II: "Ser, His, Asp arrangements in proteolytic and nonproteolytic proteins".
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cattle; Histidine; Humans; Kallikreins; Mice; Molecular Sequence Data; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases; Tissue Kallikreins | 1994 |
A prevalent amino acid polymorphism at codon 98 in the hepatocyte nuclear factor-1alpha gene is associated with reduced serum C-peptide and insulin responses to an oral glucose challenge.
Topics: Administration, Oral; Adult; Aged; Alanine; Amino Acids; Asparagine; C-Peptide; Codon; DNA-Binding Proteins; Female; Glucose; Glucose Tolerance Test; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Insulin; Insulin Secretion; Isoleucine; Leucine; Male; Middle Aged; Nuclear Proteins; Polymorphism, Genetic; Serine; Transcription Factors; Valine | 1997 |
High-affinity binding of bioactive glycosylation-inhibiting factor to antigen-primed T cells and natural killer cells.
Topics: Alanine; Animals; Asparagine; Binding Sites; Cell Line; Cysteine; Escherichia coli; Humans; Hybridomas; Killer Cells, Natural; Kinetics; Lymphocyte Activation; Lymphokines; Macrophages; Mice; Mice, Inbred BALB C; Mutagenesis, Site-Directed; Point Mutation; Prostatic Secretory Proteins; Recombinant Proteins; Serine; Suppressor Factors, Immunologic; T-Lymphocytes, Regulatory; Tumor Necrosis Factor-alpha | 1997 |
Increase of the protease activity of aqualysin I, a thermostable serine protease, by replacing Asn219 near the catalytic residue Ser222.
Topics: Asparagine; Catalysis; Enzyme Stability; Hydrolysis; Kinetics; Serine; Serine Endopeptidases; Temperature; Thermus | 1997 |
The substitution of a single amino acid residue (Ser-116 --> Asp) alters NADP-containing glucose-fructose oxidoreductase of Zymomonas mobilis into a glucose dehydrogenase with dual coenzyme specificity.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Coenzymes; Glucose 1-Dehydrogenase; Glucose Dehydrogenases; Molecular Sequence Data; NADP; Oxidoreductases; Point Mutation; Sequence Alignment; Serine; Substrate Specificity; Zymomonas | 1997 |
Regulation of N-linked core glycosylation: use of a site-directed mutagenesis approach to identify Asn-Xaa-Ser/Thr sequons that are poor oligosaccharide acceptors.
Topics: Amino Acids; Antigens, Viral; Asparagine; Binding Sites; Glutamine; Glycoproteins; Glycosylation; Mutagenesis, Site-Directed; Oligosaccharides; Rabies virus; Serine; Structure-Activity Relationship; Threonine; Viral Envelope Proteins | 1997 |
Microdialysis of human breast tissue during the menstrual cycle.
Topics: Adipose Tissue; Adult; Amino Acids; Asparagine; Aspartic Acid; Breast; Chromatography, High Pressure Liquid; Female; Glycine; Humans; Lactic Acid; Menstrual Cycle; Microdialysis; Ornithine; Pyruvic Acid; Serine; Threonine; Tyrosine | 1997 |
Development of a rapid assay for detecting gyrA mutations in Escherichia coli and determination of incidence of gyrA mutations in clinical strains isolated from patients with complicated urinary tract infections.
Topics: Anti-Infective Agents; Asparagine; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Escherichia coli Infections; Genes, Bacterial; Humans; Incidence; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Serine; Urinary Tract Infections | 1997 |
Characterization and expression of two chicken cDNAs encoding ubiquitin fused to ribosomal proteins of 52 and 80 amino acids.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Base Sequence; Chick Embryo; Chickens; Cloning, Molecular; Gene Expression; Genome; Humans; Male; Molecular Sequence Data; Molecular Structure; Phylogeny; Polymerase Chain Reaction; Protein Biosynthesis; Pyrimidines; Rats; Ribonucleases; Ribosomal Proteins; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serine; Spermatogenesis; Ubiquitins | 1997 |
Complete scanning of the CDK4 gene by denaturing gradient gel electrophoresis: a novel missense mutation but low overall frequency of mutations in sporadic metastatic malignant melanoma.
Topics: Asparagine; Biopsy; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; DNA Mutational Analysis; Electrophoresis, Polyacrylamide Gel; Humans; Melanoma; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Proto-Oncogene Mas; Proto-Oncogene Proteins; Serine; Tumor Cells, Cultured | 1997 |
Heterozygous lipoprotein lipase deficiency: frequency in the general population, effect on plasma lipid levels, and risk of ischemic heart disease.
Topics: Adult; Aged; Aged, 80 and over; Apolipoprotein A-I; Asparagine; Cholesterol, HDL; Coronary Artery Disease; Female; Gene Frequency; Glutamic Acid; Glycine; Heterozygote; Humans; Isoleucine; Lipids; Lipoprotein Lipase; Male; Middle Aged; Phenotype; Point Mutation; Risk Factors; Serine; Triglycerides | 1997 |
Sporadic congenital hyperthyroidism due to a spontaneous germline mutation in the thyrotropin receptor gene.
Topics: Animals; Asparagine; Cloning, Molecular; COS Cells; DNA; Gene Expression; Germ-Line Mutation; Humans; Hyperthyroidism; Infant; Leukocytes; Male; Polymorphism, Restriction Fragment Length; Receptors, Thyrotropin; Sequence Analysis, DNA; Serine; Transfection | 1997 |
The O-glycosylated stalk domain is required for apical sorting of neurotrophin receptors in polarized MDCK cells.
Topics: Animals; Asparagine; Cell Line; Cell Polarity; Cytoplasm; Dogs; Glycosylation; Humans; Polysaccharides; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Recombinant Proteins; Serine; Solubility; Structure-Activity Relationship; Threonine; Transfection | 1997 |
Structure and function of poly(3-hydroxybutyrate) depolymerase from Alcaligenes faecalis T1.
Topics: Alcaligenes; Asparagine; Aspartic Acid; Carboxylic Ester Hydrolases; Chromosome Inversion; DNA Primers; DNA, Bacterial; Gene Expression; Glycine; Histidine; Plasmids; Point Mutation; Polymerase Chain Reaction; Recombinant Fusion Proteins; Sequence Deletion; Serine; Trypsin | 1997 |
Regulatory phosphorylation of plant phosphoenolpyruvate carboxylase: role of a conserved basic residue upstream of the phosphorylation site.
Topics: Asparagine; Aspartic Acid; Binding Sites; Conserved Sequence; Enzyme Activation; Enzyme Inhibitors; Glucose-6-Phosphate; Lysine; Malates; Mutagenesis, Site-Directed; Phosphoenolpyruvate Carboxylase; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Serine; Zea mays | 1997 |
Proguanil resistance in Plasmodium falciparum African isolates: assessment by mutation-specific polymerase chain reaction and in vitro susceptibility testing.
Topics: Africa; Amino Acid Substitution; Animals; Asparagine; Codon; DNA, Protozoan; Drug Resistance, Microbial; Humans; Malaria, Falciparum; Microbial Sensitivity Tests; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Proguanil; Sequence Analysis, DNA; Serine; Tetrahydrofolate Dehydrogenase; Triazines | 1997 |
A polymorphism in the glucocorticoid receptor gene may be associated with and increased sensitivity to glucocorticoids in vivo.
Topics: Aged; Animals; Asparagine; Cells, Cultured; Cohort Studies; COS Cells; Dexamethasone; Female; Genetic Carrier Screening; Humans; Hydrocortisone; Insulin; Lymphocyte Activation; Lymphocytes; Male; Mammary Tumor Virus, Mouse; Mice; Middle Aged; Point Mutation; Polymorphism, Genetic; Receptors, Glucocorticoid; Recombinant Proteins; Serine; Transcription, Genetic | 1998 |
Neurotransmitters in cerebrospinal fluid reflect pathological activity.
Topics: Adult; Aged; Asparagine; Aspartic Acid; Blood-Brain Barrier; Central Nervous System Diseases; Female; Glutamic Acid; Glutamine; Glycine; Humans; L-Lactate Dehydrogenase; Male; Middle Aged; Neurotransmitter Agents; Serine; Taurine | 1997 |
A novel missense mutation (S18N) in the 5' non-HMG box region of the SRY gene in a patient with partial gonadal dysgenesis and his normal male relatives.
Topics: Adolescent; Adult; Asparagine; Child, Preschool; DNA-Binding Proteins; Gonadal Dysgenesis; High Mobility Group Proteins; Humans; Karyotyping; Male; Nuclear Proteins; Point Mutation; Sequence Homology, Nucleic Acid; Serine; Sex Determination Processes; Sex-Determining Region Y Protein; Transcription Factors | 1998 |
Substitution of Asn for Ser543 in the large fragment of Taq DNA polymerase increases the efficiency of synthesis of long DNA molecules.
Topics: Asparagine; Bacteriophage lambda; DNA, Viral; Mutagenesis, Site-Directed; Serine; Taq Polymerase | 1998 |
The amino acid following an asn-X-Ser/Thr sequon is an important determinant of N-linked core glycosylation efficiency.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antigens, Viral; Asparagine; Cell-Free System; Glycoproteins; Glycosylation; Mutagenesis, Site-Directed; Plasmids; Rabies virus; Serine; Threonine; Viral Envelope Proteins | 1998 |
Involvement of glutamic acid 278 in the redox reaction of the cytochrome c oxidase from Paracoccus denitrificans investigated by FTIR spectroscopy.
Topics: Asparagine; Aspartic Acid; Deuterium Oxide; Electron Transport Complex IV; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Oxidation-Reduction; Paracoccus denitrificans; Serine; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared | 1998 |
Identification of the catalytic triad of the protein D2 protease in Pseudomonas aeruginosa.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Carbapenems; Catalysis; Endopeptidases; Glutamine; Histidine; Imipenem; Ion Channels; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Porins; Pseudomonas aeruginosa; Serine | 1998 |
Purification and characterization of recombinant rabbit cytosolic serine hydroxymethyltransferase.
Topics: Animals; Asparagine; Aspartic Acid; Cloning, Molecular; Cytosol; Escherichia coli; Glycine Hydroxymethyltransferase; Isoelectric Focusing; Isomerism; Kinetics; Pyridoxal Phosphate; Rabbits; Recombinant Proteins; Serine; Spectrophotometry; Tetrahydrofolates | 1998 |
Frequency of the Asn-108 and Thr-108 point mutations in the dihydrofolate reductase gene in Plasmodium falciparum from southwest Colombia.
Topics: Adolescent; Adult; Animals; Asparagine; Child; Child, Preschool; Colombia; DNA, Protozoan; Female; Gene Frequency; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Serine; Tetrahydrofolate Dehydrogenase; Threonine | 1998 |
Cryocrystallography and microspectrophotometry of a mutant (alpha D60N) tryptophan synthase alpha 2 beta 2 complex reveals allosteric roles of alpha Asp60.
Topics: Allosteric Regulation; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Aspartic Acid; Catalysis; Crystallization; Crystallography, X-Ray; Freezing; Imines; Indoles; Microspectrophotometry; Models, Molecular; Molecular Sequence Data; Mutagenesis; Protein Binding; Protein Structure, Secondary; Serine; Tryptophan Synthase | 1998 |
A new candidate mutation (N528S) within the von Willebrand factor propeptide identified in a Japanese patient with phenotype IIC of von Willebrand disease.
Topics: Adult; Amino Acid Substitution; Asparagine; DNA Mutational Analysis; Exons; Homozygote; Humans; Japan; Male; Pedigree; Phenotype; Point Mutation; Protein Precursors; Serine; von Willebrand Diseases; von Willebrand Factor | 1998 |
Topography of the interaction of HPr(Ser) kinase with HPr.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Bacterial Proteins; Base Sequence; Binding Sites; Escherichia coli; Histidine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Insertional; Mycoplasma; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Sequence Alignment; Sequence Homology, Amino Acid; Serine | 1998 |
Effects of glycosylation of the residue at position 14 in ovine angiotensinogen on the human renin reaction.
Topics: Amino Acid Sequence; Angiotensinogen; Animals; Asparagine; Base Sequence; Blotting, Western; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Electrophoresis, Polyacrylamide Gel; Glycosylation; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Renin; Sequence Analysis; Serine; Sheep | 1998 |
Membrane cofactor protein: importance of N- and O-glycosylation for complement regulatory function.
Topics: Animals; Antigens, CD; Asparagine; Cell Fractionation; CHO Cells; Clone Cells; Complement Activation; Complement C3b; Complement C4b; Cricetinae; Cytoprotection; Glutamine; Glycosylation; Humans; Hydrolysis; Kinetics; Membrane Cofactor Protein; Membrane Glycoproteins; Mutagenesis, Site-Directed; Proline; Protein Structure, Tertiary; Sequence Deletion; Serine; Threonine; Transfection | 1998 |
Effect of exceptional valine replacement for highly conserved alanine-55 on the catalytic site structure of chymotrypsin-like serine protease.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cattle; Chymotrypsin; Histidine; Models, Molecular; Molecular Sequence Data; Protein C; Protein Conformation; Sequence Alignment; Serine; Threonine; Valine | 1998 |
A mutation Ser213/Asn in the hexokinase 1 from Schizosaccharomyces pombe increases its affinity for glucose.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Conserved Sequence; Fermentation; Glucose; Hexokinase; Isoenzymes; Kinetics; Molecular Sequence Data; Mutation; Oxygen Consumption; Recombinant Proteins; Saccharomyces cerevisiae; Schizosaccharomyces; Sequence Homology, Amino Acid; Serine | 1998 |
The effect of two frequent amino acid variants of the hepatocyte nuclear factor-1alpha gene on estimates of the pancreatic beta-cell function in Caucasian glucose-tolerant first-degree relatives of type 2 diabetic patients.
Topics: Adult; Amino Acid Substitution; Asparagine; C-Peptide; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Female; Genetic Variation; Glucose Tolerance Test; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Insulin; Islets of Langerhans; Isoleucine; Leucine; Male; Middle Aged; Nuclear Proteins; Serine; Transcription Factors; White People | 1998 |
Contribution of a conserved asparagine to the conformational stability of ribonucleases Sa, Ba, and T1.
Topics: Asparagine; Bacterial Proteins; Conserved Sequence; Crystallography, X-Ray; Enzyme Stability; Hydrogen Bonding; Isoenzymes; Models, Molecular; Protein Conformation; Protein Denaturation; Ribonuclease T1; Ribonucleases; Serine; Urea | 1998 |
Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.
Topics: Adenine Phosphoribosyltransferase; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Enzyme Activation; Glutamic Acid; Guanine; Guanosine Monophosphate; Humans; Hypoxanthine Phosphoribosyltransferase; Isoleucine; Lysine; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Purines; Ribonucleotides; Serine; Structure-Activity Relationship; Substrate Specificity; Tritrichomonas foetus; Tyrosine; Xanthine | 1998 |
The function of the p190 Rho GTPase-activating protein is controlled by its N-terminal GTP binding domain.
Topics: 3T3 Cells; Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Conserved Sequence; COS Cells; DNA-Binding Proteins; Enzyme Activation; GTPase-Activating Proteins; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; JNK Mitogen-Activated Protein Kinases; Kinetics; Mice; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Nuclear Proteins; Phosphoproteins; Receptors, Muscarinic; Recombinant Proteins; Repressor Proteins; Serine; Transfection | 1998 |
Electron transfer between QA and QB in photosystem II is thermodynamically perturbed in phototolerant mutants of Synechocystis sp. PCC 6803.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Cyanobacteria; Electron Transport; Light; Molecular Sequence Data; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Phenylalanine; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Plastoquinone; Serine; Thermodynamics; Thermoluminescent Dosimetry | 1999 |
Contribution to Tl+, K+, and Na+ binding of Asn776, Ser775, Thr774, Thr772, and Tyr771 in cytoplasmic part of fifth transmembrane segment in alpha-subunit of renal Na,K-ATPase.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Binding Sites; Cytoplasm; Hydroxides; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Potassium; Protein Structure, Tertiary; Recombinant Proteins; Serine; Sodium; Sodium-Potassium-Exchanging ATPase; Swine; Thallium; Threonine; Tyrosine | 1998 |
The active site of phosphorylating glyceraldehyde-3-phosphate dehydrogenase is not designed to increase the nucleophilicity of a serine residue.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; Enzyme Activation; Esters; Geobacillus stearothermophilus; Glyceraldehyde 3-Phosphate; Glyceraldehyde-3-Phosphate Dehydrogenases; Hot Temperature; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; NAD; Phosphorylation; Protease Inhibitors; Serine; Tosyl Compounds | 1999 |
Hydrogen bonds between short polar side chains and peptide backbone: prevalence in proteins and effects on helix-forming propensities.
Topics: Asparagine; Aspartic Acid; Glutamine; Hydrogen Bonding; Kinetics; Protein Structure, Secondary; Serine; Threonine | 1999 |
Site-directed mutagenesis of phosphate-contacting amino acids of bovine pancreatic deoxyribonuclease I.
Topics: Amino Acids; Animals; Arginine; Asparagine; Cattle; Deoxyribonuclease I; DNA; Hydrolysis; Mutagenesis, Site-Directed; RNA, Transfer, Tyr; Serine; Substrate Specificity; Sugar Phosphates; Threonine; Thymidine; Tyrosine | 1999 |
Mutation S543N in the thumb subdomain of the Taq DNA polymerase large fragment suppresses pausing associated with the template structure.
Topics: Asparagine; Bacteriophage lambda; DNA, Viral; Point Mutation; Serine; Taq Polymerase; Templates, Genetic | 1999 |
Active sites of diacylglycerol kinase from Escherichia coli are shared between subunits.
Topics: Alanine; Asparagine; Aspartic Acid; Binding Sites; Circular Dichroism; Diacylglycerol Kinase; Enzyme Activation; Escherichia coli; Genetic Complementation Test; Glutamine; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Serine; Structure-Activity Relationship | 1999 |
Single amino acid substitution of serine82 to asparagine in first intracellular loop of human cholecystokinin (CCK)-B receptor confers full cyclic AMP responses to CCK and gastrin.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Binding Sites; Calcium; Cells, Cultured; Cholecystokinin; Cyclic AMP; Gastrins; Humans; Molecular Sequence Data; Mutagenesis; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sequence Homology, Amino Acid; Serine | 1999 |
Variant Bernard-Soulier syndrome due to homozygous Asn45Ser mutation in the platelet glycoprotein (GP) IX in seven patients of five unrelated Finnish families.
Topics: Amino Acid Substitution; Asparagine; Bernard-Soulier Syndrome; Female; Finland; Genetic Variation; Heterozygote; Homozygote; Humans; Male; Pedigree; Platelet Glycoprotein GPIb-IX Complex; Point Mutation; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Serine | 1999 |
Modulation of the affinity and selectivity of RGS protein interaction with G alpha subunits by a conserved asparagine/serine residue.
Topics: Animals; Asparagine; Binding, Competitive; Conserved Sequence; Cysteine; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Lysine; Mutagenesis, Site-Directed; Proline; Protein Binding; Proteins; Receptors, Cell Surface; RGS Proteins; Serine | 1999 |
A new transthyretin variant (Ser23Asn) associated with familial amyloidosis in a Portuguese patient.
Topics: Adult; Amino Acid Substitution; Amyloidosis; Asparagine; Chromatography, High Pressure Liquid; Humans; Immunoelectrophoresis; Isoelectric Focusing; Male; Polymorphism, Restriction Fragment Length; Portugal; Prealbumin; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 1999 |
Partial glycosylation of Asn2181 in human factor V as a cause of molecular and functional heterogeneity. Modulation of glycosylation efficiency by mutagenesis of the consensus sequence for N-linked glycosylation.
Topics: Asparagine; Carbohydrate Conformation; Chromatography, Ion Exchange; Consensus Sequence; Factor V; Factor Va; Glycoside Hydrolases; Glycosylation; Humans; Models, Molecular; Mutagenesis, Site-Directed; Peptide Fragments; Prothrombin Time; Recombinant Proteins; Serine; Threonine; Thrombin | 1999 |
Buried, charged, non-ion-paired aspartic acid 76 contributes favorably to the conformational stability of ribonuclease T1.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Enzyme Stability; Hydrogen-Ion Concentration; Ions; Models, Chemical; Point Mutation; Protein Conformation; Protein Denaturation; Ribonuclease T1; Serine; Static Electricity | 1999 |
Significance of metal ions in galactose-1-phosphate uridylyltransferase: an essential structural zinc and a nonessential structural iron.
Topics: Asparagine; Binding Sites; Chromatography, Affinity; Circular Dichroism; Cysteine; Dialysis; Edetic Acid; Enzyme Activation; Escherichia coli; Histidine; Iron; Kinetics; Ligands; Mutagenesis, Site-Directed; Phenanthrolines; Recombinant Proteins; Serine; Structure-Activity Relationship; Triazines; UDPglucose-Hexose-1-Phosphate Uridylyltransferase; Uridine Diphosphate Glucose; Zinc | 1999 |
Fibrinogen Niigata with impaired fibrin assembly: an inherited dysfibrinogen with a Bbeta Asn-160 to Ser substitution associated with extra glycosylation at Bbeta Asn-158.
Topics: Amino Acid Substitution; Asparagine; Female; Fibrin; Fibrinogen; Glycosylation; Humans; Middle Aged; Point Mutation; Serine | 1999 |
The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
Topics: Apoenzymes; Asparagine; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Crystallography, X-Ray; Cysteine; Escherichia coli; Glutamine; Histidine; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Peptide Fragments; Serine; Stereoisomerism | 1999 |
Deamidation of asparagine residues in a recombinant serine hydroxymethyltransferase.
Topics: Amides; Animals; Asparagine; Aspartic Acid; Catalysis; Enzyme Stability; Escherichia coli; Glycine Hydroxymethyltransferase; Humans; Isoelectric Point; Kinetics; Liver; Mutagenesis, Site-Directed; Mutation; Rabbits; Recombinant Proteins; Serine; Structure-Activity Relationship; Tetrahydrofolates | 1999 |
Isolation of a glycosylated form of the chicken eggshell protein ovocleidin and determination of the glycosylation site. Alternative glycosylation/phosphorylation at an N-glycosylation sequon.
Topics: Animals; Asparagine; Chickens; Chromatography, High Pressure Liquid; Egg Proteins; Electrophoresis, Polyacrylamide Gel; Glycosylation; Phosphorylation; Serine | 1999 |
Presence of 2-furoylmethyl derivatives in hydrolysates of processed tomato products.
Topics: Alanine; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Freeze Drying; Furans; gamma-Aminobutyric Acid; Glutamic Acid; Hydrolysis; Lysine; Maillard Reaction; Serine; Solanum lycopersicum; Threonine | 2000 |
Identification of residues involved in the interaction of Staphylococcus aureus fibronectin-binding protein with the (4)F1(5)F1 module pair of human fibronectin using heteronuclear NMR spectroscopy.
Topics: Adhesins, Bacterial; Amino Acids; Asparagine; Bacterial Proteins; Binding Sites; Carbon Isotopes; Carrier Proteins; Fibronectins; Humans; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Peptide Mapping; Repetitive Sequences, Amino Acid; Serine; Staphylococcus aureus | 2000 |
Improving low-temperature catalysis in the hyperthermostable Pyrococcus furiosus beta-glucosidase CelB by directed evolution.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Bacterial Proteins; beta-Glucosidase; Binding Sites; Catalysis; Directed Molecular Evolution; Enzyme Activation; Enzyme Stability; Gene Library; Genetic Variation; Glucosides; Glycosylation; Hot Temperature; Kinetics; Molecular Sequence Data; Mutagenesis; Point Mutation; Pyrococcus furiosus; Serine; Temperature | 2000 |
Functional role of transmembrane helix 7 in the activation of the heptahelical lutropin receptor.
Topics: Amino Acid Sequence; Animals; Asparagine; Chorionic Gonadotropin; COS Cells; Cyclic AMP; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Rats; Receptors, LH; Serine; Signal Transduction; Structure-Activity Relationship; Threonine; Transfection | 2000 |
Clinical and radiographic features of a family with hypochondroplasia owing to a novel Asn540Ser mutation in the fibroblast growth factor receptor 3 gene.
Topics: Achondroplasia; Amino Acid Substitution; Asparagine; Child; Female; Humans; Mutation; Protein-Tyrosine Kinases; Radiography; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Fibroblast Growth Factor; Serine | 2000 |
Deterministic features of side-chain main-chain hydrogen bonds in globular protein structures.
Topics: Amino Acids; Asparagine; Aspartic Acid; Crystallization; Glutamic Acid; Glutamine; Histidine; Hydrogen Bonding; Protein Conformation; Protein Structure, Secondary; Proteins; Serine; Threonine | 2000 |
Tumor necrosis factor-alpha activation of NF-kappa B requires the phosphorylation of Ser-471 in the transactivation domain of c-Rel.
Topics: Amino Acid Sequence; Amino Acid Substitution; Apoptosis; Asparagine; Cell Nucleus; Clone Cells; DNA-Binding Proteins; Genes, rel; Humans; I-kappa B Proteins; Jurkat Cells; Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Point Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-rel; Recombinant Proteins; Serine; T-Lymphocytes; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2000 |
Characterization of beta-galactosidase mutations Asp332-->Asn and Arg148-->Ser, and a polymorphism, Ser532-->Gly, in a case of GM1 gangliosidosis.
Topics: Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Base Sequence; beta-Galactosidase; CHO Cells; COS Cells; Cricetinae; DNA Primers; Fluorescent Antibody Technique; Gangliosidosis, GM1; Glycine; Humans; Mutation, Missense; Serine | 2000 |
Mutational analysis of metallo-beta-lactamase CcrA from Bacteroides fragilis.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Bacterial Proteins; Bacteroides fragilis; beta-Lactamases; Cysteine; Deuterium; DNA Mutational Analysis; DNA, Bacterial; Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; Kinetics; Metalloproteins; Mutagenesis, Site-Directed; Protons; Recombinant Proteins; Serine; Solvents; Zinc | 2000 |
Association between mutations of the follicle-stimulating-hormone receptor and repeated twinning.
Topics: Adenine; Adult; Alanine; Asparagine; Codon; Exons; Female; Genetic Linkage; Guanine; Humans; Phenotype; Point Mutation; Receptors, FSH; Serine; Threonine; Twins, Dizygotic | 2000 |
A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling.
Topics: Analgesics, Opioid; Animals; Asparagine; Aspartic Acid; Cells, Cultured; COS Cells; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Mutagenesis, Site-Directed; Narcotics; Polymorphism, Single Nucleotide; Proline; Receptors, Opioid, mu; Serine; Signal Transduction; Sulfur Radioisotopes | 2001 |
Interaction between the Asn291Ser variant of the LPL gene and insulin resistance on dyslipidaemia in high risk individuals for Type 2 diabetes mellitus.
Topics: Aged; Amino Acid Substitution; Apolipoproteins; Asparagine; Blood Pressure; Cholesterol; Cholesterol, HDL; Chromosomes, Human, Pair 8; Diabetes Mellitus, Type 2; Female; Finland; Gene Frequency; Genetic Variation; Genotype; Homeostasis; Humans; Hyperlipidemias; Hypertriglyceridemia; Insulin Resistance; Lipoprotein Lipase; Male; Middle Aged; Risk Factors; Serine; Triglycerides | 2000 |
Redesigning the substrate specificity of an enzyme: isocitrate dehydrogenase.
Topics: 3-Isopropylmalate Dehydrogenase; Alcohol Oxidoreductases; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Enzyme Activation; Escherichia coli; Glutamic Acid; Helix-Loop-Helix Motifs; Isocitrate Dehydrogenase; Isocitrates; Malates; Molecular Sequence Data; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Protein Engineering; Protein Structure, Secondary; Recombinant Fusion Proteins; Serine; Substrate Specificity; Thermus thermophilus; Thiobacillus; Valine | 2000 |
DNA polymerase beta: contributions of template-positioning and dNTP triphosphate-binding residues to catalysis and fidelity.
Topics: Animals; Arginine; Asparagine; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Deoxyribonucleotides; DNA Polymerase beta; DNA-Binding Proteins; Glutamic Acid; Kinetics; Lysine; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Rats; Recombinant Proteins; Serine; Structure-Activity Relationship; Templates, Genetic | 2000 |
A helical turn motif in Mss4 is a critical determinant of Rab binding and nucleotide release.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Conserved Sequence; Evolution, Molecular; Guanine Nucleotide Exchange Factors; Guanosine Diphosphate; Helix-Turn-Helix Motifs; Kinetics; Mice; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Structure, Tertiary; Proteins; rab GTP-Binding Proteins; Rats; Sequence Homology, Amino Acid; Serine | 2001 |
Identification of human CYP2C19 residues that confer S-mephenytoin 4'-hydroxylation activity to CYP2C9.
Topics: Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Asparagine; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Histidine; Humans; Hydroxylation; Isoleucine; Kinetics; Mephenytoin; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Peptide Fragments; Proline; Recombinant Fusion Proteins; Serine; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Substrate Specificity; Threonine | 2001 |
A novel mutation in the keratin 13 gene causing oral white sponge nevus.
Topics: Adenine; Adolescent; Asparagine; Chromosome Mapping; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 17; Codon; Epithelium; Exons; Genetic Linkage; Guanine; Hamartoma; Humans; Keratins; Leukoplakia, Oral; Male; Mouth Diseases; Mutation, Missense; Protein Structure, Tertiary; Scotland; Serine | 2001 |
In vivo modifications of the maize mitochondrial small heat stress protein, HSP22.
Topics: Alternative Splicing; Amino Acid Sequence; Asparagine; Aspartic Acid; Base Sequence; Chromatography; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; DNA, Complementary; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Heat-Shock Proteins; Introns; Mass Spectrometry; Mitochondria; Molecular Sequence Data; Phosphorylation; Serine; Zea mays | 2001 |
Role of phylogenetically conserved amino acids in folding of Na,K-ATPase.
Topics: Alanine; Amino Acid Substitution; Amino Acids; Animals; Asparagine; Cell Membrane; Conserved Sequence; Endoplasmic Reticulum; Enzyme Activation; Gene Expression Regulation, Fungal; Lysine; Mutagenesis, Site-Directed; Peptide Fragments; Phylogeny; Protein Folding; Recombinant Proteins; RNA, Messenger; Saccharomyces cerevisiae; Serine; Sodium-Potassium-Exchanging ATPase; Swine; Temperature; Threonine | 2001 |
Mutation of residues 423 (Met/Ile), 444 (Thr/Met), and 506 (Asn/Ser) confer cholesteryl esterase activity on rat lung carboxylesterase. Ser-506 is required for activation by cAMP-dependent protein kinase.
Topics: Acetylcholinesterase; Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Carboxylesterase; Carboxylic Ester Hydrolases; Cloning, Molecular; Cyclic AMP-Dependent Protein Kinases; Cytosol; DNA, Complementary; Enzyme Activation; Humans; Isoleucine; Liver; Lung; Methionine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Protein Structure, Secondary; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Sterol Esterase; Threonine | 2001 |
Vaccinia topoisomerase mutants illuminate conformational changes during closure of the protein clamp and assembly of a functional active site.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Binding Sites; Catalytic Domain; DNA; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Magnesium Chloride; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Conformation; Sequence Homology, Amino Acid; Serine; Sodium Chloride; Time Factors; Tyrosine; Vaccinia virus | 2001 |
Modeling and mutational analysis of a putative sodium-binding pocket on the dopamine D2 receptor.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Cells, Cultured; DNA Mutational Analysis; Humans; Models, Molecular; Molecular Sequence Data; Protein Conformation; Receptors, Dopamine D2; Serine; Sodium | 2001 |
Synergistic interactions of multiple mutations on catalysis during the hydroxylation reaction of p-hydroxybenzoate hydroxylase: studies of the Lys297Met, Asn300Asp, and Tyr385Phe mutants reconstituted with 8-Cl-flavin.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Alanine; Amino Acid Substitution; Anaerobiosis; Asparagine; Aspartic Acid; Catalysis; Flavin-Adenine Dinucleotide; Hydroxylation; Lysine; Methionine; Mutagenesis, Site-Directed; Oxidation-Reduction; Parabens; Phenylalanine; Riboflavin; Serine; Spectrophotometry; Substrate Specificity; Tyrosine | 2001 |
Amino acid metabolism of bovine blastocysts derived from parthenogenetically activated or in vitro fertilized oocytes.
Topics: Alanine; Amino Acids; Animals; Asparagine; Blastocyst; Cattle; Cryopreservation; Culture Techniques; Female; Fertilization in Vitro; Glutamic Acid; Glutamine; Glycine; Oocytes; Parthenogenesis; Serine | 1998 |
Disulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modules.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Chromatography, High Pressure Liquid; Cysteine; Cystine; Disulfides; Electrophoresis, Polyacrylamide Gel; Frizzled Receptors; Glycosylation; Heparin; Humans; Lysine; Mass Spectrometry; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Netrin Receptors; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Proteins; Receptors, Cell Surface; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Subtilisin; Time Factors; Xenopus | 2002 |
Influenza a virus M2 ion channel activity is essential for efficient replication in tissue culture.
Topics: Amantadine; Animals; Antiviral Agents; Asparagine; Cell Line; Cell Line, Transformed; Culture Techniques; Dogs; Genes, Viral; Humans; Influenza A virus; Ion Channels; Nucleocapsid Proteins; Nucleoproteins; Protein Biosynthesis; RNA-Binding Proteins; Serine; Viral Core Proteins; Viral Matrix Proteins; Virus Replication | 2002 |
Amino acid runs in eukaryotic proteomes and disease associations.
Topics: Animals; Arabidopsis; Asparagine; Caenorhabditis elegans; Drosophila melanogaster; Genome; Genome, Human; Glutamine; Humans; Leucine; Saccharomyces cerevisiae; Serine; Species Specificity; Transcription, Genetic | 2002 |
Polymorphisms in the platelet-endothelial cell adhesion molecule-1 (PECAM-1) gene, Asn563Ser and Gly670Arg, associated with myocardial infarction in the Japanese.
Topics: Amino Acid Substitution; Antigens, CD; Arginine; Asian People; Asparagine; Coronary Stenosis; Female; Gene Frequency; Genotype; Glycine; Humans; Japan; Linkage Disequilibrium; Male; Middle Aged; Mutation, Missense; Myocardial Infarction; Platelet Endothelial Cell Adhesion Molecule-1; Polymorphism, Genetic; Reference Values; Serine | 2001 |
Essential hydrophilic carboxyl-terminal regions including cysteine residues of the yeast stretch-activated calcium-permeable channel Mid1.
Topics: Alanine; Alleles; Asparagine; Binding Sites; Calcium; Calcium Channels; Codon; Codon, Nonsense; Cysteine; Fungal Proteins; Hydroxylamine; Immunoblotting; Membrane Glycoproteins; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Threonine; Time Factors; Tryptophan; Two-Hybrid System Techniques | 2002 |
Hydration effects of heparin on antithrombin probed by osmotic stress.
Topics: Alanine; Antithrombins; Asparagine; Binding Sites; Heparin; Isoleucine; Kinetics; Leucine; Models, Molecular; Osmotic Pressure; Protein Binding; Serine; Spectrometry, Fluorescence; Thermodynamics; Threonine; Time Factors; Tryptophan; Valine; Water; X-Rays | 2002 |
Importance of Na,K-ATPase residue alpha 1-Arg544 in the segment Arg544-Asp567 for high-affinity binding of ATP, ADP, or MgATP.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Conserved Sequence; Cysteine; Glutamic Acid; Magnesium; Mutagenesis, Site-Directed; Peptide Fragments; Phosphorylation; Saccharomyces cerevisiae; Serine; Sodium-Potassium-Exchanging ATPase; Swine; Thermodynamics | 2002 |
Probing substrate binding to metallo-beta-lactamase L1 from Stenotrophomonas maltophilia by using site-directed mutagenesis.
Topics: Asparagine; beta-Lactamases; Binding Sites; Carbapenems; Cephalosporins; Computational Biology; Isoleucine; Kinetics; Metals; Models, Molecular; Mutagenesis, Site-Directed; Penicillins; Phenylalanine; Protein Binding; Serine; Stenotrophomonas maltophilia; Tyrosine | 2002 |
Volatile anesthetic actions on the GABAA receptors: contrasting effects of alpha 1(S270) and beta 2(N265) point mutations.
Topics: Amino Acid Sequence; Anesthetics, Inhalation; Asparagine; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; Halothane; Humans; Isoflurane; Point Mutation; Receptors, GABA-A; Serine | 2002 |
Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability.
Topics: Arginine; Asparagine; Aspartic Acid; Crystallography, X-Ray; Humans; Models, Molecular; Muramidase; Mutation; Protein Binding; Protein Conformation; Serine; Thermodynamics; Tyrosine; Valine; Water | 2002 |
Polymorphisms and the differential antiviral activity of the chicken Mx gene.
Topics: 3T3 Cells; Amino Acid Substitution; Animals; Antiviral Agents; Asparagine; Cells, Cultured; Chick Embryo; Chickens; Gene Expression Regulation; Genetic Variation; Genetic Vectors; Green Fluorescent Proteins; GTP-Binding Proteins; Influenza A virus; Luminescent Proteins; Mice; Myxovirus Resistance Proteins; Phylogeny; Polymorphism, Genetic; Protein Biosynthesis; Proteins; Serine; Transfection; Vesicular stomatitis Indiana virus; Virus Cultivation | 2002 |
Prevalence of the HIV protease mutation N88S causing hypersensitivity to amprenavir.
Topics: Amino Acid Substitution; Anti-HIV Agents; Asparagine; Carbamates; Drug Hypersensitivity; Furans; Gene Frequency; HIV; HIV Protease; Humans; Mutation; Serine; Sulfonamides | 2002 |
Modulation of the electrostatic charge at the active site of foot-and-mouth-disease-virus leader proteinase, an unusual papain-like enzyme.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Binding Sites; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Escherichia coli; Eukaryotic Initiation Factor-4G; Foot-and-Mouth Disease Virus; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Molecular; Mutagenesis, Site-Directed; Papain; Peptide Initiation Factors; Serine; Static Electricity | 2002 |
S111N mutation in the helical domain of human Gs(alpha) reduces its GDP/GTP exchange rate.
Topics: Adenylyl Cyclases; Aluminum Compounds; Amino Acid Substitution; Asparagine; Fluorides; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Models, Molecular; Point Mutation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Cell Surface; Serine; Trypsin | 2002 |
Molecular modeling and site-specific mutagenesis of the histamine-binding site of the histamine H4 receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Binding Sites; Calcium; Cells, Cultured; Histamine; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Sequence Homology, Amino Acid; Serine; Tyrosine | 2002 |
Lack of association of two lipoprotein lipase polymorphisms with Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Apolipoproteins E; Asparagine; Brain; Brain Chemistry; DNA Mutational Analysis; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Genotype; Humans; Lipoprotein Lipase; Low Density Lipoprotein Receptor-Related Protein-1; Neurons; Plaque, Amyloid; Point Mutation; Polymorphism, Genetic; Serine | 2002 |
Improving nucleoside diphosphate kinase for antiviral nucleotide analogs activation.
Topics: Acyclovir; Animals; Antiviral Agents; Asparagine; Binding Sites; Cell Division; Dictyostelium; Escherichia coli; Histidine; Humans; Kinetics; Models, Chemical; Models, Molecular; Mutation; Nucleoside-Diphosphate Kinase; Phosphorylation; Polymerase Chain Reaction; Protein Binding; Serine; Temperature; Transfection | 2002 |
Mutations in the putative pore-forming segment favor short-lived wild-type Kir2.1 pore conformations.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Cysteine; Glycosylation; Ion Channel Gating; Isoleucine; Mice; Molecular Sequence Data; Patch-Clamp Techniques; Peptide Fragments; Phenylalanine; Point Mutation; Potassium Channels, Inwardly Rectifying; Protein Conformation; Protein Structure, Tertiary; Serine; Spodoptera; Threonine; Time Factors; Tyrosine | 2002 |
Amino acid content of cell cultures infected with Cowdria ruminantium propagated in a protein-free medium.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Bacteriological Techniques; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media, Serum-Free; Ehrlichia ruminantium; Glutamine; Glycine; Heartwater Disease; Proline; Ruminants; Serine; Tryptophan | 2002 |
Excitatory amino acid release in the spinal cord caused by plantar incision in the rat.
Topics: Animals; Asparagine; Aspartic Acid; Dermatologic Surgical Procedures; Glutamic Acid; Glutamine; Glycine; Male; Microdialysis; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord | 2002 |
Liddle's syndrome associated with a point mutation in the extracellular domain of the epithelial sodium channel gamma subunit.
Topics: Adult; Amino Acid Sequence; Animals; Asparagine; Base Sequence; Epithelial Sodium Channels; Female; Genes, Dominant; Humans; Hypertension; Hypokalemia; Male; Molecular Sequence Data; Oocytes; Pedigree; Point Mutation; Serine; Sodium Channels; Syndrome; Threonine; Xenopus | 2002 |
Distinct sites regulating grayanotoxin binding and unbinding to D4S6 of Na(v)1.4 sodium channel as revealed by improved estimation of toxin sensitivity.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cell Membrane; Cloning, Molecular; Diterpenes; DNA, Complementary; Electrophysiology; Kinetics; Models, Chemical; Molecular Sequence Data; Muscle Proteins; Mutagenesis, Site-Directed; Mutation; NAV1.5 Voltage-Gated Sodium Channel; Phenylalanine; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rats; Serine; Sodium Channels; Transfection; Tyrosine | 2003 |
Recognition of nucleic acid bases and base-pairs by hydrogen bonding to amino acid side-chains.
Topics: Amino Acids; Arginine; Asparagine; Base Composition; Base Pairing; Computer Simulation; Crystallography, X-Ray; Databases, Factual; DNA; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Models, Structural; Nucleic Acid Conformation; Nucleic Acids; Protein Binding; Protein Structure, Secondary; Protons; Purines; Pyrimidines; RNA; Serine | 2003 |
Central role of a serine phosphorylation site within duck hepatitis B virus core protein for capsid trafficking and genome release.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Binding Sites; Blotting, Western; Capsid; Cell Nucleus; Centrifugation, Density Gradient; Chickens; DNA, Circular; DNA, Viral; Hepatitis B Virus, Duck; Hydrogen Bonding; Microscopy, Confocal; Mutation; Phosphorylation; Precipitin Tests; Serine; Transfection | 2003 |
Thapsigargin selectively rescues the trafficking defective LQT2 channels G601S and F805C.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Cation Transport Proteins; Cell Line; Cell Membrane; Cell Nucleus; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Glycine; Humans; Long QT Syndrome; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Transport; Recombinant Proteins; Serine; Thapsigargin; Trans-Activators; Transcriptional Regulator ERG | 2003 |
Deletions of any single residues in Glu40-Ser48 loop connecting a domain and the first transmembrane helix of sarcoplasmic reticulum Ca(2+)-ATPase result in almost complete inhibition of conformational transition and hydrolysis of phosphoenzyme intermedia
Topics: Adenosine Triphosphate; Animals; Asparagine; Calcium-Transporting ATPases; COS Cells; Enzyme Activation; Gene Deletion; Glutamic Acid; Hydrogen Bonding; Hydrolysis; Lysine; Microsomes; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Conformation; Protein Structure, Tertiary; Rabbits; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine | 2003 |
Lipoprotein lipase activity and common gene variants in severely hypertriglyceridemic patients with and without diabetes.
Topics: Adult; Apolipoproteins; Asparagine; Aspartic Acid; Diabetes Complications; Diabetes Mellitus; Female; Genetic Variation; Glutamic Acid; Glycine; Humans; Hyperlipoproteinemia Type IV; Lipoprotein Lipase; Male; Middle Aged; Phenotype; Serine; Severity of Illness Index | 2003 |
Another phenotype of frontotemporal dementia and parkinsonism linked to chromosome-17 (FTDP-17) with a missense mutation of S305N closely resembling Pick's disease.
Topics: Asparagine; Chromosomes, Human, Pair 17; Dementia; Dentate Gyrus; Genetic Linkage; Humans; Immunohistochemistry; Inclusion Bodies; Male; Microscopy, Electron; Middle Aged; Mutation, Missense; Parkinsonian Disorders; Phenotype; Pick Disease of the Brain; Serine; tau Proteins | 2003 |
Functional importance of polar and charged amino acid residues in transmembrane helix 14 of multidrug resistance protein 1 (MRP1/ABCC1): identification of an aspartate residue critical for conversion from a high to low affinity substrate binding state.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Animals; Anions; Asparagine; Aspartic Acid; Binding Sites; Biological Transport; Cell Line; Cytoplasm; Drug Resistance; Estradiol; Humans; Hydrolysis; Kinetics; Leukotriene C4; Lysine; Mice; Models, Molecular; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Mutation; Nucleic Acid Synthesis Inhibitors; Protein Binding; Protein Structure, Tertiary; Rats; Serine; Time Factors; Transfection | 2003 |
Role of follicle-stimulating hormone receptor Ser680Asn polymorphism in the efficacy of follicle-stimulating hormone.
Topics: Adult; Alleles; Amino Acid Sequence; Asparagine; Drug Administration Schedule; Female; Follicle Stimulating Hormone; Gene Frequency; Genetic Markers; Homozygote; Humans; Ovulation Induction; Phenotype; Polymorphism, Genetic; Receptors, FSH; Recombinant Proteins; Retrospective Studies; Serine; Treatment Outcome | 2003 |
Effect of cultural conditions on growth and metabolite uptake by serine-glycine auxotrophs of Escherichia coli.
Topics: Amino Acids; Asparagine; Biological Transport; Escherichia coli; Glycine; Homoserine; Serine; Threonine | 1962 |
[Thin layer chromatographic separation of amino acids on cellulose layers].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Methionine; Serine; Tryptophan; Tyrosine; Valine | 1962 |
[MECHANISMS OF AMINO ACID SYNTHESIS IN LEAVES. STUDIES USING RADIOCARBON].
Topics: Alanine; Amino Acids; Aminobutyrates; Ammonium Compounds; Asparagine; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Chromatography; Darkness; Glutamates; Glutamine; Glycine; Light; Methionine; Nitrates; Plant Proteins; Proteins; Quaternary Ammonium Compounds; Research; Serine; Threonine | 1963 |
[ON THE QUANTITATIVE DETERMINATION OF AMINO ACIDS USING HIGH VOLTAGE ELECTROPHORESIS].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Blood Protein Electrophoresis; Glutamates; Histidine; Leucine; Lysine; Methionine; Ornithine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
THE ROLE OF DISPENSABLE AMINO ACIDS IN THE NUTRITION OF THE RAT.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bicarbonates; Caseins; Cystine; Dietary Proteins; Glutamates; Glycine; Growth; Histidine; Isoleucine; Lysine; Methionine; Phenylalanine; Proline; Proteins; Rats; Research; Serine; Tyrosine | 1964 |
[SEPARATION OF AMINO ACIDS BY CHROMATOGRAPHY ON THIN LAYERS OF DIETHYLAMINOETHYL CELLULOSE].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
QUANTITATIVE COLONIAL GROWTH OF MAMMALIAN CELLS IN FIBRIN CELLS.
Topics: Asparagine; Fibrin; Folic Acid; Immune Sera; Mast Cells; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Serine; Thrombin; Tissue Culture Techniques | 1964 |
QUANTITATIVE COMPARISON BETWEEN OXYTOCIN AND FOUR RELATED NEUROHYPOPSIAL PEPTIDES ON THE HUMAN UTERUS IN SITU.
Topics: Asparagine; Biological Assay; Female; Humans; Isoleucine; Oxytocics; Oxytocin; Peptides; Pharmacology; Pituitary Hormones, Posterior; Postpartum Period; Serine; Uterus | 1964 |
CATALYTIC REACTIONS INVOLVING AZOMETHINES. IV. RATES AND EQUILIBRIA OF IMINE FORMATION WITH PYRIDINE-4-ALDEHYDE AND VARIOUS AMINO ACIDS.
Topics: Alanine; Aldehydes; Amino Acids; Arginine; Asparagine; Aspartic Acid; Azo Compounds; Biochemical Phenomena; Biochemistry; Glutamates; Glycine; Imines; Leucine; Phenylalanine; Pyridines; Research; Serine; Spectrophotometry; Thiosemicarbazones; Valine | 1964 |
BIOSYNTHESIS IN VICIA SATIVA (COMMON VETCH) OF GAMMA-GLUTAMYL-BETA-CYANOALANINE FROM (BETA-14-C)SERINE AND ITS RELATION TO CYANIDE METABOLISM.
Topics: Alanine; Amino Acids; Asparagine; Carbon Isotopes; Chromatography; Cyanides; Dipeptides; Glutamates; Metabolism; Plants; Research; Serine; Vicia sativa | 1964 |
[APPLICATION OF THIN-LAYER CHROMATOGRAPHY TO SEQUENCE ANALYSIS OF PEPTIDES. 3. NONDESTRUCTIVE DETECTION OF AMINO ACIDS ON THE THIN-LAYER CHROMATOGRAM].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chromatography; Chromatography, Thin Layer; Histidine; Peptides; Proline; Research; Sequence Analysis; Serine; Tyrosine; Valine | 1964 |
NEMATODE BIOCHEMISTRY. V. INTERMEDIARY METABOLISM AND AMINO ACID INTERCONVERSIONS IN CAENORHABDITIS BRIGGSAE.
Topics: Acetates; Alanine; Amino Acids; Aminobutyrates; Animals; Asparagine; Aspartic Acid; Bicarbonates; Caenorhabditis; Carbon Dioxide; Chromatography; Formates; Glutamates; Glutamine; Glycine; Malates; Nematoda; Phenylalanine; Research; Serine; Taurine; Tyrosine | 1965 |
CHANGES IN THE NERVE CELL PROTEINS IN DOGS DURING RESUSCITATION FROM THE STATE OF CLINICAL DEATH.
Topics: Alanine; Aminobutyrates; Ammonia; Arginine; Asparagine; Brain Chemistry; Cerebral Cortex; Cystine; Death; Dogs; Glutamates; Glutamine; Glycine; Histidine; Histocytochemistry; Hypothermia; Hypothermia, Induced; Leucine; Lysine; Methionine; Nerve Tissue Proteins; Neurons; Pathology; Phenylalanine; Proteins; Research; Resuscitation; Serine | 1965 |
Follicle-stimulating hormone receptor polymorphisms in women with normogonadotropic anovulatory infertility.
Topics: Anovulation; Asparagine; Case-Control Studies; Cross-Sectional Studies; Female; Gene Frequency; Genotype; Humans; Infertility, Female; Polymorphism, Genetic; Receptors, FSH; Serine; Threonine | 2003 |
Amprenavir resistance imparted by the I50V mutation in HIV-1 protease can be suppressed by the N88S mutation.
Topics: Asparagine; Carbamates; Drug Resistance, Viral; Furans; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Isoleucine; Microbial Sensitivity Tests; Mutation; Serine; Sulfonamides; Valine | 2003 |
Deciphering the molecular basis of the broad substrate specificity of alpha-glucosidase from Bacillus sp. SAM1606.
Topics: alpha-Glucosidases; Amino Acid Sequence; Amino Acids; Asparagine; Bacillus; Binding Sites; Catalysis; Evolution, Molecular; Glycine; Isomaltose; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Oligo-1,6-Glucosidase; Phylogeny; Plasmids; Proline; Serine; Substrate Specificity; Threonine; Trehalose | 2003 |
Residue Asp-189 controls both substrate binding and the monovalent cation specificity of thrombin.
Topics: Alanine; Allosteric Site; Asparagine; Aspartic Acid; Binding Sites; Cations; Dose-Response Relationship, Drug; Glutamine; Humans; Hydrolysis; Ions; Kinetics; Lithium; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Conformation; Rubidium; Serine; Sodium; Substrate Specificity; Thrombin; Trypsin | 2004 |
A rare polymorphism affects a mitogen-activated protein kinase site in synapsin III: possible relationship to schizophrenia.
Topics: Animals; Animals, Newborn; Asparagine; Base Sequence; Brain; Cyclin-Dependent Kinases; DNA Mutational Analysis; Embryo, Mammalian; Enzyme Inhibitors; Exons; Family Health; Female; Genotype; Hippocampus; Humans; Immunoblotting; Leucine; Linkage Disequilibrium; Male; Mice; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Neuropeptides; Pedigree; Phosphoproteins; Phosphorylation; Polymerase Chain Reaction; Polymorphism, Genetic; Precipitin Tests; Psychiatric Status Rating Scales; Schizophrenia; Sequence Analysis, Protein; Serine; Synapsins | 2004 |
Single chain antibodies that recognize the N-glycosylation site.
Topics: Amino Acid Sequence; Animals; Antibodies; Asparagine; Binding Sites; Blotting, Western; Cattle; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Glycosylation; Hexosyltransferases; Humans; Immunoglobulin Variable Region; Kinetics; Membrane Proteins; Oligopeptides; Peptide Library; Serine; Serum Albumin, Bovine; Threonine | 2004 |
Molecular and functional differences induced in thrombospondin-1 by the single nucleotide polymorphism associated with the risk of premature, familial myocardial infarction.
Topics: Asparagine; Circular Dichroism; Genetic Variation; Humans; Myocardial Infarction; Platelet Aggregation; Polymorphism, Single Nucleotide; Risk Factors; Serine; Thrombospondin 1 | 2004 |
Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes.
Topics: Adult; Amino Acid Sequence; Animals; Antigen-Presenting Cells; Asparagine; B-Lymphocyte Subsets; Cathepsin G; Cathepsins; Cell Line; Cell Line, Transformed; Cell Separation; Cysteine Endopeptidases; Humans; Hydrolysis; Lymphocyte Activation; Lysine; Lysosomes; Mice; Molecular Sequence Data; Myelin Basic Protein; Phenylalanine; Protein Processing, Post-Translational; Serine; Serine Endopeptidases | 2004 |
Evidence for a proton transfer network and a required persulfide-bond-forming cysteine residue in Ni-containing carbon monoxide dehydrogenases.
Topics: Alanine; Aldehyde Oxidoreductases; Asparagine; Bacterial Proteins; Biological Transport; Catalysis; Clostridium; Cysteine; Electron Spin Resonance Spectroscopy; Histidine; Lysine; Multienzyme Complexes; Mutagenesis, Site-Directed; Nickel; Protons; Serine; Sulfides | 2004 |
A mutation (N177S) in the structurally conserved helix initiation peptide motif of keratin 5 causes a mild EBS phenotype.
Topics: Adult; Amino Acid Motifs; Asparagine; Base Sequence; DNA; DNA Mutational Analysis; Epidermolysis Bullosa Simplex; Female; Heterozygote; Humans; Keratin-5; Keratins; Mutation, Missense; Pedigree; Phenotype; Polymerase Chain Reaction; Serine | 2004 |
Role of Asn-16 and Ser-19 in anthopleurin B binding. Implications for the electrostatic nature of Na(V) site 3.
Topics: Amino Acid Substitution; Animals; Asparagine; Binding Sites; Cells, Cultured; Cnidarian Venoms; Electrophysiology; Humans; Intercellular Signaling Peptides and Proteins; Models, Molecular; Mutagenesis, Site-Directed; Peptides; Protein Binding; Sea Anemones; Serine; Sodium Channels; Static Electricity | 2004 |
Pick's disease pathology of a missense mutation of S305N of frontotemporal dementia and parkinsonism linked to chromosome 17: another phenotype of S305N.
Topics: Asparagine; Base Sequence; Brain; Dementia; DNA Mutational Analysis; Genetic Linkage; Heterozygote; Humans; Immunohistochemistry; Magnetic Resonance Imaging; Male; Microscopy, Electron; Middle Aged; Mutation, Missense; Parkinsonian Disorders; Phenotype; Pick Disease of the Brain; Polymorphism, Restriction Fragment Length; Serine; tau Proteins | 2004 |
Biophysical characterization of natural and mutant fluorescent proteins cloned from zooxanthellate corals.
Topics: Animals; Anisotropy; Anthozoa; Asparagine; Biophysical Phenomena; Biophysics; Cloning, Molecular; DNA Primers; Green Fluorescent Proteins; Guanidine; Kinetics; Luminescent Proteins; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Phylogeny; Point Mutation; Protein Folding; Protein Structure, Secondary; Serine; Spectrophotometry; Temperature; Time Factors | 2004 |
Crystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediates.
Topics: Acyltransferases; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Codon; Crystallography, X-Ray; Cysteine; Escherichia coli; Evolution, Molecular; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Naphthols; Naphthoquinones; Oxalic Acid; Polyketide Synthases; Protein Conformation; Protein Structure, Tertiary; Serine; Streptomyces; Streptomyces coelicolor | 2004 |
Identification of a novel epitope in the thyroid-stimulating hormone receptor ectodomain acting as intramolecular signaling interface.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Cell Line; Cell Membrane; Cell Separation; Computational Biology; COS Cells; Cyclic AMP; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Epitopes; Flow Cytometry; Humans; Interleukin-8; Microscopy, Confocal; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Thyrotropin; Serine; Signal Transduction; Time Factors; Transfection | 2004 |
Crystal structure of the Bowman-Birk inhibitor from barley seeds in ternary complex with porcine trypsin.
Topics: Amino Acid Sequence; Animals; Arginine; Asparagine; Binding Sites; Crystallography, X-Ray; Hordeum; Hydrogen Bonding; Models, Molecular; Molecular Structure; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Seeds; Serine; Solvents; Swine; Trypsin; Trypsin Inhibitor, Bowman-Birk Soybean | 2004 |
A polymorphism in thrombospondin-1 associated with familial premature coronary artery disease alters Ca2+ binding.
Topics: Amino Acid Motifs; Amino Acid Sequence; Asparagine; Binding Sites; Calcium; Coronary Artery Disease; Humans; In Vitro Techniques; Kinetics; Molecular Sequence Data; Peptide Fragments; Polymorphism, Single Nucleotide; Recombinant Proteins; Serine; Thrombospondin 1 | 2004 |
Pantothenate kinase-associated neurodegeneration initially presenting as postural tremor alone in a Japanese family with homozygous N245S substitutions in the pantothenate kinase gene.
Topics: Acanthocytes; Adult; Anticonvulsants; Asian People; Asparagine; Basal Ganglia; Brain Mapping; Clonazepam; DNA Mutational Analysis; Family Health; Female; Homozygote; Humans; Magnetic Resonance Imaging; Mutation; Neurodegenerative Diseases; Phosphotransferases (Alcohol Group Acceptor); Propanolamines; Serine; Staining and Labeling; Tremor | 2004 |
Proteasomal degradation of human CYP1B1: effect of the Asn453Ser polymorphism on the post-translational regulation of CYP1B1 expression.
Topics: Alleles; Amino Acid Substitution; Animals; Aryl Hydrocarbon Hydroxylases; Asparagine; Chlorocebus aethiops; COS Cells; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Enzyme Stability; Gene Expression Regulation, Enzymologic; Polymorphism, Genetic; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Serine | 2005 |
Identification of the transmembrane metal binding site in Cu+-transporting PIB-type ATPases.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Archaeoglobus fulgidus; Asparagine; Binding Sites; Cation Transport Proteins; Cell Membrane; Conserved Sequence; Copper; Copper-Transporting ATPases; Metals; Methionine; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Phosphates; Phosphorylation; Serine; Structure-Activity Relationship; Tyrosine | 2004 |
Ser95, Asn97, and Thr78 are important for the catalytic function of porcine NADP-dependent isocitrate dehydrogenase.
Topics: Animals; Asparagine; Catalysis; Circular Dichroism; Hydrogen-Ion Concentration; Isocitrate Dehydrogenase; Kinetics; Models, Molecular; Molecular Weight; Mutation; Recombinant Proteins; Serine; Swine; Threonine | 2005 |
Prediction of severity of symptoms in iatrogenic ovarian hyperstimulation syndrome by follicle-stimulating hormone receptor Ser680Asn polymorphism.
Topics: Adult; Alleles; Asparagine; Female; Fertilization in Vitro; Gene Frequency; Genetic Predisposition to Disease; Humans; Iatrogenic Disease; Ovarian Hyperstimulation Syndrome; Polymorphism, Genetic; Receptors, FSH; Serine; Severity of Illness Index; White People | 2004 |
Analysis of human cytochrome P450 2C8 substrate specificity using a substrate pharmacophore and site-directed mutants.
Topics: Amiodarone; Animals; Arginine; Aryl Hydrocarbon Hydroxylases; Asparagine; Catalysis; Chromans; Computer Simulation; Cytochrome P-450 CYP2C8; Diclofenac; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Indoles; Isoleucine; Models, Molecular; Mutagenesis, Site-Directed; Paclitaxel; Phenylalanine; Rabbits; Serine; Substrate Specificity; Sulfonamides; Thiazolidinediones; Tretinoin; Troglitazone | 2004 |
Compound heterozygosity for a novel nine-nucleotide deletion and the Asn45Ser missense mutation in the glycoprotein IX gene in a patient with Bernard-Soulier syndrome.
Topics: Asparagine; Base Sequence; Bernard-Soulier Syndrome; Child; DNA; Female; Flow Cytometry; Gene Deletion; Heterozygote; Humans; Mutation, Missense; Platelet Glycoprotein GPIb-IX Complex; Serine | 2005 |
Serine-to-asparagine substitution in the GyrA gene leads to quinolone resistance in moxifloxacin-exposed Chlamydia pneumoniae.
Topics: Anti-Infective Agents; Asparagine; Aza Compounds; Chlamydophila pneumoniae; DNA Gyrase; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Moxifloxacin; Point Mutation; Quinolines; Quinolones; Serial Passage; Serine | 2005 |
A rapid and simple method for detection of Asn363Ser polymorphism of the human glucocorticoid receptor gene.
Topics: Adult; Aged; Aged, 80 and over; Asparagine; Base Sequence; DNA Mutational Analysis; Exons; Female; Genetic Testing; Humans; Male; Middle Aged; Molecular Sequence Data; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Receptors, Glucocorticoid; Serine; Time Factors | 2004 |
Phenotypes of the N88S Berardinelli-Seip congenital lipodystrophy 2 mutation.
Topics: Action Potentials; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Asparagine; Diabetes Mellitus, Lipoatrophic; DNA Mutational Analysis; Electric Stimulation; Electromyography; Family Health; Female; GTP-Binding Protein gamma Subunits; Haplotypes; Humans; Male; Middle Aged; Mutation, Missense; Neural Conduction; Pedigree; Phenotype; Reaction Time; Serine; Sex Factors | 2005 |
Biochemical characterization of recombinant acetyl xylan esterase from Aspergillus awamori expressed in Pichia pastoris: mutational analysis of catalytic residues.
Topics: Acetylesterase; Amino Acid Substitution; Asparagine; Aspergillus; Catalytic Domain; DNA Mutational Analysis; Enzyme Stability; Mutagenesis, Site-Directed; Pichia; Recombinant Proteins; Serine; Substrate Specificity | 2005 |
Hierarchical phosphorylation of the TNF-alpha receptor, TNF-R1, by p42Mapk/Erk at basic Pro-directed kinase sites.
Topics: Animals; Asparagine; Cell Membrane; Cells, Cultured; Chlorocebus aethiops; Consensus Sequence; COS Cells; Cytoplasm; Mice; Mice, Inbred C3H; Mitogen-Activated Protein Kinase 1; Mutagenesis, Site-Directed; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Receptors, Tumor Necrosis Factor, Type I; Sequence Deletion; Serine; Tumor Necrosis Factor-alpha | 2005 |
Point mutations at the type I Cu ligands, Cys457 and Met467, and at the putative proton donor, Asp105, in Myrothecium verrucaria bilirubin oxidase and reactions with dioxygen.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Copper; Cysteine; Dithionite; Fungal Proteins; Glutamic Acid; Glutamine; Hypocreales; Ligands; Methionine; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Point Mutation; Protons; Serine | 2005 |
A single amino acid change in the C-terminal domain of the matrix protein M1 of influenza B virus confers mouse adaptation and virulence.
Topics: Adaptation, Physiological; Amino Acid Substitution; Animals; Asparagine; Female; Influenza B virus; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Protein Structure, Tertiary; Serial Passage; Serine; Viral Matrix Proteins; Virulence; Virus Replication | 2005 |
c-MYC Asn11Ser is associated with increased risk for familial breast cancer.
Topics: Amino Acid Sequence; Asparagine; Breast Neoplasms; Female; Genetic Predisposition to Disease; Humans; Molecular Sequence Data; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins c-myc; Sequence Homology, Amino Acid; Serine | 2005 |
Lennard-Jones parameters for the combined QM/MM method using the B3LYP/6-31G*/AMBER potential.
Topics: Acetamides; Amino Acids; Asparagine; Aspartic Acid; Computer Simulation; Histidine; Hydrogen Bonding; Lysine; Models, Molecular; Molecular Structure; Proteins; Serine; Thermodynamics | 2005 |
A three-dimensional pharmacophore model for 5-hydroxytryptamine6 (5-HT6) receptor antagonists.
Topics: Animals; Asparagine; Aspartic Acid; Binding Sites; Cattle; Drug Design; Hydrogen Bonding; Models, Molecular; Protein Conformation; Receptors, Serotonin; Rhodopsin; Serine; Serotonin Antagonists | 2005 |
Identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the M(3) muscarinic acetylcholine receptor.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Blotting, Western; Carbachol; Cell Membrane; Chlorocebus aethiops; COS Cells; Cross-Linking Reagents; Cysteine; Disulfides; Dose-Response Relationship, Drug; Kinetics; Leucine; Ligands; Luciferases; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oxygen; Phosphatidylinositols; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rats; Receptors, Muscarinic; Serine; Transfection | 2005 |
Epitope analysis of immunoglobulins against gp20, a GPI-anchored protein of the human sperm surface homologous to leukocyte antigen CD52.
Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antigens; Antigens, CD; Antigens, Neoplasm; Asparagine; Blotting, Western; CD52 Antigen; Cell Membrane; Chromatography, Affinity; Chromatography, Ion Exchange; Chromosome Mapping; Electrophoresis, Polyacrylamide Gel; Epitopes; Glycoproteins; Glycosylphosphatidylinositols; Humans; Immunoblotting; Immunoglobulins; Lymphocytes; Male; Microscopy, Fluorescence; Oligosaccharides; Polysaccharides; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Serine; Sialoglycoproteins; Spermatozoa; Temperature | 2005 |
Molecular basis of cysteine biosynthesis in plants: structural and functional analysis of O-acetylserine sulfhydrylase from Arabidopsis thaliana.
Topics: Amino Acid Sequence; Arabidopsis; Asparagine; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Cysteine Synthase; Cytosol; Databases, Protein; Glutamine; Kinetics; Ligands; Methionine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plant Proteins; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Serine; Serine O-Acetyltransferase; Threonine | 2005 |
Functional plasticity in the substrate binding site of beta-secretase.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Asparagine; Aspartic Acid Endopeptidases; Binding Sites; Catalysis; Computer Simulation; Crystallography, X-Ray; Endopeptidases; Enzyme Inhibitors; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Sequence Data; Oligopeptides; Protein Conformation; Protein Structure, Secondary; Protons; Serine; Substrate Specificity; Temperature; Tyrosine; Water | 2005 |
The mechanism of membrane targeting of human sphingosine kinase 1.
Topics: Amino Acid Sequence; Asparagine; Cell Line; Cell Membrane; DNA Mutational Analysis; Green Fluorescent Proteins; Humans; Kinetics; Lipids; Lysophospholipids; Mass Spectrometry; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Molecular Sequence Data; Mutation; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Pressure; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Sphingosine; Surface Plasmon Resonance; Threonine; Time Factors; Transfection | 2005 |
Mechanistic pathways of formation of acrylamide from different amino acids.
Topics: Acrylamide; Acrylamides; Acrylates; Amino Acids; Ammonia; Asparagine; Aspartic Acid; beta-Alanine; Carbohydrates; Carnosine; Creatine; Cysteine; Fructose; Gas Chromatography-Mass Spectrometry; Hydrolysis; Mass Spectrometry; Models, Chemical; Pyruvic Acid; Serine; Time Factors | 2005 |
Glucocerebrosidase gene mutations and Parkinson disease in the Norwegian population.
Topics: Adult; Aged; Aged, 80 and over; Asparagine; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Glucosylceramidase; Heterozygote; Humans; Leucine; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Serine | 2006 |
Functional role of catalytic triad and oxyanion hole-forming residues on enzyme activity of Escherichia coli thioesterase I/protease I/phospholipase L1.
Topics: Alanine; Asparagine; Catalytic Domain; Crystallography; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Glycine; Kinetics; Lysophospholipase; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Oligonucleotides; Periplasmic Proteins; Protein Conformation; Serine | 2006 |
Polymorphisms of the glucocorticoid receptor gene and major depression.
Topics: Adult; Analysis of Variance; Antidepressive Agents; Asparagine; Case-Control Studies; Corticotropin-Releasing Hormone; Depressive Disorder, Major; Dexamethasone; DNA Mutational Analysis; Exons; Female; Genetic Predisposition to Disease; Humans; Hydrocortisone; Linkage Disequilibrium; Male; Middle Aged; Neuropsychological Tests; Polymorphism, Genetic; Receptors, Glucocorticoid; Serine; Severity of Illness Index; Time Factors | 2006 |
HLA-B*4904, a new allele identified in two unrelated individuals from the same Italian region.
Topics: Alleles; Amino Acid Substitution; Asparagine; Base Sequence; Exons; Genetic Variation; Histidine; HLA-B Antigens; Humans; Italy; Molecular Sequence Data; Polymorphism, Single-Stranded Conformational; Sequence Analysis, DNA; Serine | 2006 |
Considerations on the lactate consumption by CHO cells in the presence of galactose.
Topics: Alanine; Animals; Asparagine; Bioreactors; Carbohydrate Metabolism; Cell Culture Techniques; Cell Survival; CHO Cells; Cricetinae; Culture Media; Galactose; Gluconeogenesis; Glucose; Glutamic Acid; Lactic Acid; Models, Biological; Serine | 2006 |
Subangstrom crystallography reveals that short ionic hydrogen bonds, and not a His-Asp low-barrier hydrogen bond, stabilize the transition state in serine protease catalysis.
Topics: Asparagine; Catalysis; Crystallography; Histidine; Hydrogen; Hydrogen Bonding; Models, Molecular; Protein Conformation; Serine; Serine Endopeptidases | 2006 |
Hydrophilic iminosugar active-site-specific chaperones increase residual glucocerebrosidase activity in fibroblasts from Gaucher patients.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; Cells, Cultured; Enzyme Inhibitors; Fibroblasts; Gaucher Disease; Glucosylceramidase; Humans; Imino Sugars; Molecular Chaperones; Serine | 2006 |
The iminosugar isofagomine increases the activity of N370S mutant acid beta-glucosidase in Gaucher fibroblasts by several mechanisms.
Topics: Asparagine; Binding Sites; Catalysis; Cells, Cultured; Endoplasmic Reticulum; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Gaucher Disease; Glucosylceramidase; Humans; Hydrogen-Ion Concentration; Imino Pyranoses; Lysosomes; Mutation; Piperidines; Protein Folding; Serine; Sodium Dodecyl Sulfate | 2006 |
The role of phosphorylation on the structure and dynamics of phospholamban: a model from molecular simulations.
Topics: Asparagine; Calcium-Binding Proteins; Computer Simulation; Cytoplasm; Hydrogen Bonding; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Serine; Water | 2007 |
Optical mapping of ventricular arrhythmias in LQTS mice with SCN5A mutation N1325S.
Topics: Animals; Arrhythmias, Cardiac; Asparagine; Cardiac Complexes, Premature; Long QT Syndrome; Mexiletine; Mice; Mutation; NAV1.5 Voltage-Gated Sodium Channel; Nifedipine; Serine; Sodium Channels | 2007 |
Determinants of positive cooperativity between strychnine-like allosteric modulators and N-methylscopolamine at muscarinic receptors.
Topics: Allosteric Regulation; Amino Acid Substitution; Asparagine; Mutagenesis, Site-Directed; N-Methylscopolamine; Proline; Protein Conformation; Receptors, Muscarinic; Serine; Strychnine; Threonine; Valine | 2006 |
Knops blood group haplotypes among distinct Brazilian populations.
Topics: Amino Acid Substitution; Asian People; Asparagine; Black People; Blood Group Antigens; Brazil; Gene Frequency; Genotype; Haplotypes; Humans; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Receptors, Complement; Serine; White People | 2007 |
Retinoids restore normal cyclic nucleotide sensitivity of mutant ion channels associated with cone dystrophy.
Topics: Animals; Asparagine; Cattle; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Humans; Ion Channels; Mutation; Oocytes; Patch-Clamp Techniques; Retinitis Pigmentosa; Retinoids; Serine; Transduction, Genetic; Vitamin A; Xenopus | 2006 |
Diagnostic value of ultrastructural nerve examination in Charcot-Marie-Tooth disease: two CMT 1B cases with pseudo-recessive inheritance.
Topics: Adult; Asparagine; Charcot-Marie-Tooth Disease; Child; Consanguinity; Demyelinating Diseases; DNA Mutational Analysis; Female; Genes, Recessive; Humans; Microscopy, Electron, Transmission; Mutation; Myelin P0 Protein; Myelin Sheath; Peripheral Nerves; Phenylalanine; Serine; Tyrosine | 2007 |
Association of the Asn306Ser variant of the SP4 transcription factor and an intronic variant in the beta-subunit of transducin with digenic disease.
Topics: Adenine; Asparagine; Blindness; Cohort Studies; Exons; Genetic Variation; GTP-Binding Protein beta Subunits; Guanine; Hispanic or Latino; Humans; Introns; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Retinal Degeneration; Serine; Sp4 Transcription Factor | 2007 |
Molecular anatomy of the alkaliphilic xylanase from Bacillus halodurans C-125.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Bacillus; Clostridium; Crystallography, X-Ray; Endo-1,4-beta Xylanases; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Sequence Alignment; Serine | 2007 |
The discoidin domain receptor 1 as a novel susceptibility gene for schizophrenia.
Topics: Adult; Aged; Aged, 80 and over; Asparagine; Chi-Square Distribution; Discoidin Domain Receptor 1; DNA Mutational Analysis; Exons; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Polymorphism, Single Nucleotide; Receptor Protein-Tyrosine Kinases; Regression Analysis; Reverse Transcriptase Polymerase Chain Reaction; Schizophrenia; Serine; Valine | 2007 |
N34S mutation in the SPINK1 gene is not associated with alternative splicing.
Topics: Adolescent; Adult; Alternative Splicing; Amino Acid Sequence; Asparagine; Base Sequence; Carrier Proteins; Cloning, Molecular; DNA Mutational Analysis; Exons; Female; Heterozygote; Homozygote; Humans; Introns; Male; Middle Aged; Molecular Sequence Data; Mutation; Pancreatitis, Chronic; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, Protein; Serine; Trypsin Inhibitor, Kazal Pancreatic | 2007 |
The effect of hinge mutations on effector binding and domain rotation in Escherichia coli D-3-phosphoglycerate dehydrogenase.
Topics: Asparagine; Chromatography, Gel; Escherichia coli; Glycine; Hydrogen Bonding; Kinetics; Models, Molecular; Mutation; Phosphoglycerate Dehydrogenase; Protein Binding; Protein Structure, Tertiary; Serine; Valine | 2007 |
A novel LRRK2 mutation in an Austrian cohort of patients with Parkinson's disease.
Topics: Aged; Asparagine; Austria; Cohort Studies; DNA Mutational Analysis; Exons; Family Health; Female; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine | 2007 |
A new type of plasma prekallikrein deficiency associated with homozygosity for Gly104Arg and Asn124Ser in apple domain 2 of the heavy-chain region.
Topics: Amino Acid Substitution; Arginine; Asparagine; Base Sequence; Blotting, Western; DNA Primers; Female; Glycine; Homozygote; Humans; Male; Pedigree; Polymerase Chain Reaction; Prekallikrein; Serine | 2007 |
Study of p.N247S KERA mutation in a British family with cornea plana.
Topics: Adult; Asparagine; Case-Control Studies; Corneal Diseases; Female; Genome, Human; Haplotypes; Humans; Linkage Disequilibrium; Male; Mutation; Pedigree; Phylogeny; Polymorphism, Single Nucleotide; Proteoglycans; Serine; United Kingdom; White People | 2007 |
Role of conserved active site residues in catalysis by phospholipase B1 from Cryptococcus neoformans.
Topics: Acyltransferases; Amino Acid Sequence; Amino Acid Substitution; Arginine; Asparagine; Binding Sites; Catalysis; Consensus Sequence; Cryptococcus neoformans; Cytosol; Genes, Fungal; Humans; Lysophospholipase; Models, Biological; Models, Molecular; Multienzyme Complexes; Mutagenesis, Site-Directed; Phospholipases A2; Phospholipids; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Serine; Species Specificity; Substrate Specificity; Virulence | 2007 |
Polymorphic variations in exon 10 of the luteinizing hormone receptor: functional consequences and associations with breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Asparagine; Breast Neoplasms; Case-Control Studies; Cell Line; Exons; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Receptors, LH; Risk Factors; Serine; Survival Analysis | 2007 |
Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin.
Topics: Amino Acid Substitution; Asparagine; Bacterial Proteins; Binding Sites; Cadherins; Calorimetry; Genetic Engineering; Genetic Variation; Glycine; Humans; Kinetics; Listeria monocytogenes; Models, Molecular; Protein Binding; Protein Conformation; Recombinant Proteins; Serine; Thermodynamics; Tyrosine | 2007 |
Molecular cloning and characterization of hemoglobin alpha and beta chains from plateau pika (Ochotona curzoniae) living at high altitude.
Topics: Adaptation, Physiological; Altitude; Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Base Sequence; Cloning, Molecular; Codon, Initiator; Codon, Terminator; Conserved Sequence; DNA Primers; DNA, Complementary; Glycine; Hemoglobin A; Hemoglobins; Humans; Lagomorpha; Molecular Sequence Data; Phenylalanine; Phylogeny; Polymerase Chain Reaction; Serine; Valine | 2007 |
Site-directed mutagenesis of five conserved residues of subunit i of the cytochrome cbb3 oxidase in Rhodobacter capsulatus.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Bacterial Proteins; Catalysis; Cytochromes c; Electron Transport Complex IV; Electrophoresis, Polyacrylamide Gel; Heme; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Subunits; Rhodobacter capsulatus; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Threonine | 2007 |
Identification of mutations in UBIAD1 following exclusion of coding mutations in the chromosome 1p36 locus for Schnyder crystalline corneal dystrophy.
Topics: Amino Acid Substitution; Asparagine; Corneal Dystrophies, Hereditary; Dimethylallyltranstransferase; Female; Humans; Leucine; Male; Mutation; Mutation, Missense; Polymorphism, Single Nucleotide; Proteins; Serine; Valine | 2007 |
N965S is a common ABCA4 variant in Stargardt-related retinopathies in the Danish population.
Topics: Adolescent; Adult; Alleles; Asparagine; ATP-Binding Cassette Transporters; Blindness; Child; Cohort Studies; Denmark; Frameshift Mutation; Fundus Oculi; Gene Deletion; Gene Frequency; Genetic Variation; Humans; Male; Middle Aged; Mutation, Missense; Phenotype; Protein Isoforms; Retinal Diseases; Serine | 2007 |
Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif.
Topics: Amino Acid Motifs; Asparagine; Biochemistry; Carbon-Carbon Lyases; Catalytic Domain; Crystallography, X-Ray; Escherichia coli; Fusarium; Glutamic Acid; Kinetics; Magnesium; Models, Chemical; Mutagenesis, Site-Directed; Serine; Tyrosine | 2008 |
Glucocerebrosidase gene mutations are associated with Parkinson's disease in southern Italy.
Topics: Aged; Asparagine; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glucosylceramidase; Humans; Italy; Leucine; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Serine | 2008 |
A combined approach of mass spectrometry, molecular modeling, and site-directed mutagenesis highlights key structural features responsible for the thermostability of Sulfolobus solfataricus carboxypeptidase.
Topics: Alkylation; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Aspartic Acid; Carboxypeptidases; Cysteine; Disulfides; Enzyme Activation; Enzyme Stability; Hot Temperature; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Mass Spectrometry; Models, Chemical; Models, Molecular; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Oxidation-Reduction; Pepsin A; Protein Engineering; Protein Structure, Secondary; Protein Subunits; Serine; Sulfolobus solfataricus; Thermodynamics; Trypsin | 2008 |
[Molecular analysis of the p.Asn 370 Ser mutation in Gaucher disease].
Topics: Amino Acid Substitution; Asparagine; Diagnosis, Differential; DNA; DNA Primers; Exons; Gaucher Disease; Glucosylceramidase; Humans; Mutation; Polymerase Chain Reaction; Restriction Mapping; Serine | 2008 |
Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity.
Topics: Allosteric Regulation; alpha-Amylases; Asparagine; Azides; Catalysis; Chlorides; Crystallography, X-Ray; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Nitrates; Nitrites; Pichia; Protein Binding; Recombinant Proteins; Serine; Static Electricity; Substrate Specificity | 2008 |
Cyclic AMP-dependent protein kinase controls energy interconversion during the catalytic cycle of the yeast copper-ATPase.
Topics: Amino Acid Sequence; Asparagine; Catalysis; Catalytic Domain; Cation Transport Proteins; Copper; Copper Transport Proteins; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Molecular Sequence Data; Mutation; Phosphorylation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine | 2008 |
Glucocerebrosidase gene mutations: a risk factor for Lewy body disorders.
Topics: Aged; Asparagine; Case-Control Studies; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glucosylceramidase; Humans; Leucine; Lewy Body Disease; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Risk Factors; Serine | 2008 |
Parkinson's disease and the heterozygous state for glucocerebrosidase mutations among Brazilians.
Topics: Adult; Asparagine; Brazil; Female; Glucosylceramidase; Heterozygote; Humans; Leucine; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Serine | 2009 |
Single-amino-acid mutation in the HA alters the recognition of H9N2 influenza virus by a monoclonal antibody.
Topics: Amino Acid Substitution; Animals; Antibodies, Monoclonal; Antibodies, Viral; Antigenic Variation; Asparagine; Birds; Cell Line; Dogs; Fluorescent Antibody Technique; Glycosylation; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A Virus, H9N2 Subtype; Influenza in Birds; Mutation; Neutralization Tests; Serine | 2008 |
[Plasmodium falciparum chloroquine and pyrimethamine resistance monitoring network with molecular tools in the Niger River valley, Republic of Niger].
Topics: Animals; Antigens, Protozoan; Antimalarials; Asparagine; Biomarkers; Chloroquine; Communicable Disease Control; Drug Resistance; Humans; Lysine; Membrane Transport Proteins; Mutation; Niger; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Serine; Tetrahydrofolate Dehydrogenase; Threonine | 2008 |
Uncertain pathogenicity of MSH2 variants N127S and G322D challenges their classification.
Topics: Asparagine; Aspartic Acid; Biliary Tract Neoplasms; Blotting, Western; Colorectal Neoplasms, Hereditary Nonpolyposis; DNA Mismatch Repair; DNA-Binding Proteins; Endometrial Neoplasms; Female; Genetic Predisposition to Disease; Germ-Line Mutation; Glycine; Humans; Immunoprecipitation; MutS Homolog 2 Protein; Pancreatic Neoplasms; Serine; Uncertainty | 2008 |
Novel mutations in the TK2 gene associated with fatal mitochondrial DNA depletion myopathy.
Topics: Asparagine; DNA Mutational Analysis; DNA, Mitochondrial; Family Health; Female; Glutamine; Humans; Infant; Male; Mitochondrial Myopathies; Multienzyme Complexes; Muscle, Skeletal; Mutation; Serine; Thymidine Kinase | 2008 |
Role of the Ser-287-Asn replacement in the hydrolysis spectrum extension of AmpC beta-lactamases in Escherichia coli.
Topics: Asparagine; Bacterial Proteins; beta-Lactamases; Cephalosporins; Escherichia coli; Escherichia coli Proteins; Hydrolysis; Microbial Sensitivity Tests; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Serine | 2009 |
Evaluation of the number of ionogenic groups of inulinase by acid-base titration.
Topics: Asparagine; Aspergillus; Fungal Proteins; Glutamic Acid; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Lysine; Protein Denaturation; Serine; Tyrosine | 2008 |
N114S mutation causes loss of ATP-induced aggregation of human phosphoribosylpyrophosphate synthetase 1.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Asparagine; Catalysis; Crystallography, X-Ray; Gout; Humans; Hydrogen Bonding; Mutagenesis, Site-Directed; Point Mutation; Protein Structure, Secondary; Recombinant Proteins; Ribose-Phosphate Pyrophosphokinase; Serine | 2009 |
Inoculation of sugarcane with Pantoea sp. increases amino acid contents in shoot tissues; serine, alanine, glutamine and asparagine permit concomitantly ammonium excretion and nitrogenase activity of the bacterium.
Topics: Alanine; Amino Acids; Asparagine; Bacterial Proteins; Glutamine; Nitrogenase; Pantoea; Quaternary Ammonium Compounds; Saccharum; Serine | 2009 |
PARK11 gene (GIGYF2) variants Asn56Ser and Asn457Thr are not pathogenic for Parkinson's disease.
Topics: Aged; Asparagine; Austria; Carrier Proteins; DNA Mutational Analysis; Egypt; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Germany; Humans; Male; Middle Aged; Parkinson Disease; Polymorphism, Single Nucleotide; Serine; Threonine; White People | 2009 |
Site-directed mutagenesis, kinetic and inhibition studies of aspartate ammonia lyase from Bacillus sp. YM55-1.
Topics: Amino Acid Substitution; Asparagine; Aspartate Ammonia-Lyase; Aspartic Acid; Bacillus; Bacterial Proteins; Binding Sites; Catalysis; Catalytic Domain; Circular Dichroism; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Malates; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Nitro Compounds; Propionates; Protein Structure, Tertiary; Serine; Substrate Specificity; Threonine | 2009 |
Hereditary thrombocytosis caused by MPLSer505Asn is associated with a high thrombotic risk, splenomegaly and progression to bone marrow fibrosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Asparagine; Child; Child, Preschool; Disease Progression; Female; Follow-Up Studies; Humans; Infant; Male; Middle Aged; Pedigree; Primary Myelofibrosis; Receptors, Thrombopoietin; Risk Factors; Serine; Splenomegaly; Thrombocytosis; Thrombopoietin; Thrombosis; Young Adult | 2010 |
Genetic loss of D-amino acid oxidase activity reverses schizophrenia-like phenotypes in mice.
Topics: Animals; Arginine; Asparagine; Aspartic Acid; Behavior, Animal; Binding Sites; Carrier Proteins; D-Amino-Acid Oxidase; Female; Glycine; Male; Mice; Mutation; Nerve Tissue Proteins; Nervous System; Phenotype; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Serine; Social Behavior; Stereoisomerism | 2010 |
Discovery and investigation of misincorporation of serine at asparagine positions in recombinant proteins expressed in Chinese hamster ovary cells.
Topics: Animals; Asparagine; CHO Cells; Cloning, Molecular; Cricetinae; Cricetulus; Escherichia coli; Glycosylation; Mass Spectrometry; Models, Biological; Peptide Mapping; Peptides; Recombinant Proteins; RNA, Transfer; Serine | 2009 |
Identification and analysis of residues contained on beta --> alpha loops of the dual-substrate (beta alpha)8 phosphoribosyl isomerase A specific for its phosphoribosyl anthranilate isomerase activity.
Topics: Aldose-Ketose Isomerases; Amino Acid Sequence; Arginine; Asparagine; Catalytic Domain; Crystallography, X-Ray; Evolution, Molecular; Kinetics; Protein Conformation; Protein Structure, Secondary; Sequence Analysis, Protein; Serine; Streptomyces coelicolor; Threonine | 2010 |
Structure of the dominant negative S17N mutant of Ras.
Topics: Amino Acid Substitution; Asparagine; Crystallography, X-Ray; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Magnesium; Models, Molecular; Protein Binding; ras Proteins; Serine; Signal Transduction; Structure-Activity Relationship | 2010 |
Surface modification of magnetic nanoparticles using asparagines-serine polypeptide designed to control interactions with cell surfaces.
Topics: Animals; Asparagine; Blood Cells; Cell Line; Cell Membrane; Cell Separation; Gene Expression; Humans; Magnetics; Magnetosomes; Magnetospirillum; Nanoparticles; Nerve Tissue Proteins; Peptides; Protein Binding; Recombinant Fusion Proteins; Serine; Surface Properties | 2010 |
Mutational analysis of GABRG2 in a Japanese cohort with childhood epilepsies.
Topics: Amino Acid Sequence; Asparagine; Child; Cohort Studies; DNA Mutational Analysis; Epilepsy, Tonic-Clonic; Female; Humans; Japan; Male; Molecular Sequence Data; Mutation, Missense; Receptors, GABA-A; Sequence Alignment; Serine | 2010 |
Control of misincorporation of serine for asparagine during antibody production using CHO cells.
Topics: Amino Acid Substitution; Animals; Antibodies, Monoclonal; Asparagine; CHO Cells; Cricetinae; Cricetulus; Protein Engineering; Serine | 2010 |
Mechanisms of unintended amino acid sequence changes in recombinant monoclonal antibodies expressed in Chinese Hamster Ovary (CHO) cells.
Topics: Amino Acid Substitution; Animals; Antibodies, Monoclonal; Asparagine; CHO Cells; Cricetinae; Cricetulus; Protein Engineering; Serine | 2010 |
Enantiospecific adsorption of amino acids on hydroxylated quartz (10 1 0).
Topics: Adsorption; Amino Acids; Asparagine; Aspartic Acid; Cysteine; Quartz; Serine; Stereoisomerism; Thermodynamics | 2010 |
Mass spectrometric analysis, automated identification and complete annotation of O-linked glycopeptides.
Topics: Acetylgalactosamine; Asparagine; Automation; Chromatography, Liquid; Galactose; Glycopeptides; Glycosylation; Mass Spectrometry; Serine; Threonine; Tryptophan | 2010 |
Bacillus subtilis SSE4 produces subtulene A, a new lipopeptide antibiotic possessing an unusual C15 unsaturated beta-amino acid.
Topics: Adipates; Amino Acids; Anti-Bacterial Agents; Antifungal Agents; Asparagine; Bacillus subtilis; Lipids; Lipopeptides; Magnetic Resonance Spectroscopy; Peptides, Cyclic; Serine; Tyrosine | 2010 |
Acquisition of Raman spectra of amino acids using portable instruments: outdoor measurements and comparison.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; beta-Alanine; Glutamic Acid; Glutamine; Glycine; Methionine; Proline; Research Design; Robotics; Serine; Spectrum Analysis, Raman; Transportation; Tryptophan; Tyrosine; Workplace | 2010 |
Emergence of amantadine-resistant avian influenza H5N1 virus in India.
Topics: Amantadine; Amino Acid Substitution; Animals; Asparagine; Chickens; Disease Outbreaks; Drug Resistance, Viral; Hemagglutinin Glycoproteins, Influenza Virus; India; Influenza A Virus, H5N1 Subtype; Influenza in Birds; Neuraminidase; Phylogeny; Poultry Diseases; RNA, Viral; Sequence Analysis, Protein; Serine; Viral Matrix Proteins | 2011 |
Lack of modulatory function of coding nucleotide polymorphism S100A2_185G>A in oral squamous cell carcinoma.
Topics: Adenine; Adult; Aged; Alleles; Amino Acid Substitution; Asparagine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cells, Cultured; Chemotactic Factors; EF Hand Motifs; Exons; Female; Genotype; Guanine; Helix-Loop-Helix Motifs; Heterozygote; Humans; KB Cells; Keratinocytes; Male; Middle Aged; Mouth Neoplasms; Open Reading Frames; Polymorphism, Genetic; Polymorphism, Single Nucleotide; S100 Proteins; Serine; Tumor Suppressor Proteins | 2011 |
Importance of position 170 in the inhibition of GES-type β-lactamases by clavulanic acid.
Topics: Anti-Bacterial Agents; Asparagine; beta-Lactamase Inhibitors; beta-Lactamases; Chromatography, Liquid; Clavulanic Acid; Enzyme Inhibitors; Glycine; Microbial Sensitivity Tests; Serine; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship | 2011 |
Rampant purifying selection conserves positions with posttranslational modifications in human proteins.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Evolution, Molecular; Humans; Models, Genetic; Phylogeny; Protein Processing, Post-Translational; Proteins; Selection, Genetic; Sequence Alignment; Serine; Threonine; Tyrosine | 2011 |
Effect of an asparagine-to-serine mutation at position 294 in neuraminidase on the pathogenicity of highly pathogenic H5N1 influenza A virus.
Topics: Amino Acid Substitution; Animals; Antiviral Agents; Asparagine; Disease Models, Animal; Drug Resistance, Viral; Female; Ferrets; Influenza A Virus, H5N1 Subtype; Male; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Neuraminidase; Orthomyxoviridae Infections; Oseltamivir; Point Mutation; Rodent Diseases; Serine; Survival Analysis; Treatment Outcome; Viral Proteins; Virulence; Virulence Factors; Virus Replication; Zanamivir | 2011 |
The G82S polymorphism promotes glycosylation of the receptor for advanced glycation end products (RAGE) at asparagine 81: comparison of wild-type rage with the G82S polymorphic variant.
Topics: Asparagine; Cell Line; Cell Membrane; Gene Expression Regulation; Glycine; Glycosylation; Humans; Inflammation; Ligands; Mutation; Polymorphism, Genetic; Protein Binding; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serine; Transfection | 2011 |
Protein kinase C-mediated phosphorylation of a single serine residue on the rat glial glutamine transporter SN1 governs its membrane trafficking.
Topics: Amino Acid Transport Systems, Neutral; Animals; Asparagine; Biotinylation; Chlorocebus aethiops; Computational Biology; Cricetinae; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamine; Histones; Immunoprecipitation; Indoles; Male; Maleimides; Membrane Potentials; Models, Molecular; Oocytes; Patch-Clamp Techniques; Phorbol Esters; Phosphorylation; Point Mutation; Protein Isoforms; Protein Kinase C; Protein Transport; Qa-SNARE Proteins; Rats; Rats, Wistar; Serine; Transfection; Xenopus laevis | 2011 |
[Association between variants of lipoprotein lipase and coronary heart disease in a Tunisian population].
Topics: Aged; Amino Acid Substitution; Asparagine; Aspartic Acid; Case-Control Studies; Coronary Disease; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genetics, Population; Genotype; Humans; Lipoprotein Lipase; Male; Middle Aged; Polymorphism, Single Nucleotide; Serine; Tunisia | 2012 |
Mutated C-terminal fragments of Clostridium perfringens enterotoxin have increased affinity to claudin-4 and reversibly modulate tight junctions in vitro.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Caco-2 Cells; Claudin-4; Enterotoxins; Humans; Intestinal Mucosa; Membrane Proteins; Molecular Sequence Data; Mutation; Serine; Tight Junctions | 2011 |
[Determination of amino acid contents in cottonseeds using near infrared reflectance spectroscopy].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Calibration; Cottonseed Oil; Cystine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Spectroscopy, Near-Infrared; Threonine; Tyrosine; Valine | 2011 |
Role of autophagy inhibitors and inducers in modulating the toxicity of trimethyltin in neuronal cell cultures.
Topics: Adenine; Adjuvants, Immunologic; Aldehydes; Analysis of Variance; Animals; Asparagine; Autophagy; Brain; Cell Count; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; L-Lactate Dehydrogenase; Lithium Chloride; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Mitochondria; Neurons; Phosphorylation; Serine; Sirolimus; Tetrazolium Salts; Thiazoles; Trimethyltin Compounds; Vacuoles | 2012 |
Rescue of a pathogenic mutant human glucagon receptor by pharmacological chaperones.
Topics: Alanine; Asparagine; Cell Membrane; Curcumin; Cyclic AMP; Drug Design; Glucagon; Green Fluorescent Proteins; HEK293 Cells; Humans; Molecular Chaperones; Mutation; Pancreatic Neoplasms; Protein Transport; Pyridines; Pyrroles; Receptors, Glucagon; Serine; Thapsigargin | 2012 |
Negative regulation of CCaMK is essential for symbiotic infection.
Topics: Alleles; Amino Acid Substitution; Asparagine; Binding Sites; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Chromosome Mapping; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Lotus; Mesorhizobium; Mutagenesis, Site-Directed; Mutation; Mycorrhizae; Phenotype; Phosphorylation; Plant Epidermis; Plant Roots; Serine; Symbiosis | 2012 |
ASN540SER mutation is associated with a mild form of hypochondroplasia: a 7 years follow-up in an Italian boy.
Topics: Adolescent; Amino Acid Substitution; Asparagine; Bone and Bones; Dwarfism; Follow-Up Studies; Humans; Italy; Limb Deformities, Congenital; Lordosis; Male; Mutation; Radiography; Receptor, Fibroblast Growth Factor, Type 3; Serine | 2012 |
Characterization of a serine-to-asparagine substitution at position 123 in the Japanese encephalitis virus E protein.
Topics: Amino Acid Substitution; Animals; Asparagine; Cell Line; Culicidae; Encephalitis Virus, Japanese; Female; Mice; Phylogeny; Serine; Viral Envelope Proteins | 2013 |
[Study of the association between alleles of the growth hormone receptor and prolactin receptor genes of bulls and the milk productivity of their daughters].
Topics: Amino Acid Substitution; Animals; Asparagine; Cattle; Female; Gene Frequency; Lactation; Male; Milk; Milk Proteins; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Receptors, Prolactin; Receptors, Somatotropin; Serine | 2012 |
Identification and origin of N-linked β-D-N-acetylglucosamine monosaccharide modifications on Arabidopsis proteins.
Topics: Acetylglucosamine; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Asparagine; Chromatography, Affinity; Cytosol; Endoplasmic Reticulum; Enzyme Activation; Glycoside Hydrolases; Glycosylation; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Conformation; Polysaccharides; Protein Folding; Recombinant Proteins; Serine; Threonine | 2013 |
A serine-to-asparagine mutation at position 314 of H5N1 avian influenza virus NP is a temperature-sensitive mutation that interferes with nuclear localization of NP.
Topics: Amino Acid Substitution; Animals; Asparagine; Cloning, Molecular; Female; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Madin Darby Canine Kidney Cells; Mice; Mice, Inbred BALB C; Nucleocapsid Proteins; Phenotype; RNA-Binding Proteins; Serine; Temperature; Viral Core Proteins | 2013 |
Isolation, structure elucidation, and iron-binding properties of lystabactins, siderophores isolated from a marine Pseudoalteromonas sp.
Topics: Asparagine; Chromatography, High Pressure Liquid; Gentisates; Gulf of Mexico; Iron; Marine Biology; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Ornithine; Peptides, Cyclic; Petroleum Pollution; Pseudoalteromonas; Serine; Siderophores | 2013 |
Association study between FSHR Ala307Thr and Ser680Asn variants and polycystic ovary syndrome (PCOS) in Northern Chinese Han women.
Topics: Adult; Alanine; Amino Acid Substitution; Asian People; Asparagine; Case-Control Studies; China; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Geography; Humans; Mutation, Missense; Polycystic Ovary Syndrome; Polymorphism, Single Nucleotide; Receptors, FSH; Serine; Threonine | 2013 |
N-terminal helix-cap in α-helix 2 modulates β-state misfolding in rabbit and hamster prion proteins.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Asparagine; Circular Dichroism; Cricetinae; Hydrogen-Ion Concentration; Models, Molecular; Molecular Sequence Data; Mutation; Prion Diseases; Prions; Protein Conformation; Protein Folding; Protein Structure, Secondary; Rabbits; Sequence Alignment; Serine; Urea | 2013 |
H2A.Z acidic patch couples chromatin dynamics to regulation of gene expression programs during ESC differentiation.
Topics: Animals; Asparagine; Cell Differentiation; Cell Lineage; Chromatin; Embryonic Development; Embryonic Stem Cells; Gene Expression Regulation, Developmental; Glycine; Histones; Mice; Nucleosomes; Promoter Regions, Genetic; Serine | 2013 |
Short tandem repeats in the inhibitory domain of the mineralocorticoid receptor: prediction of a β-solenoid structure.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Evolution, Molecular; Humans; Microsatellite Repeats; Models, Molecular; Phosphorylation; Protein Conformation; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Mineralocorticoid; Sequence Alignment; Sequence Homology, Amino Acid; Serine | 2013 |
Response to desmopressin in patients with mild hemophilia A caused by the F8 c.1910A>G, p.Asn637Ser mutation.
Topics: Asparagine; Deamino Arginine Vasopressin; Factor VIII; Hemophilia A; Humans; Mutation; Serine | 2013 |
Efficient access to enantiopure γ4-amino acids with proteinogenic side-chains and structural investigation of γ4-Asn and γ4-Ser in hybrid peptide helices.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Models, Molecular; Peptides; Protein Structure, Secondary; Serine; Solid-Phase Synthesis Techniques | 2013 |
Effect of intracellular loop 3 on intrinsic dynamics of human β2-adrenergic receptor.
Topics: Asparagine; Binding Sites; Epinephrine; Humans; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Adrenergic, beta-2; Serine | 2013 |
A Francisella virulence factor catalyses an essential reaction of biotin synthesis.
Topics: Amino Acid Sequence; Animals; Asparagine; Bacterial Proteins; Biocatalysis; Biotin; Carboxylesterase; Catalytic Domain; Female; Francisella; Genes, Essential; Gram-Negative Bacterial Infections; Histidine; Hydrolases; Mice; Mice, Inbred C57BL; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phylogeny; Protein Conformation; Protein Structure, Secondary; Serine; Virulence Factors | 2014 |
Metabolic responses of CHO cells to limitation of key amino acids.
Topics: Amino Acids; Animals; Asparagine; Cell Culture Techniques; CHO Cells; Citric Acid Cycle; Cricetinae; Cricetulus; Gas Chromatography-Mass Spectrometry; Glutamate-Ammonia Ligase; Magnetic Resonance Spectroscopy; Pyruvic Acid; Serine | 2014 |
The Ser680Asn polymorphism in the follicle-stimulating hormone receptor gene is associated with the ovarian response in controlled ovarian hyperstimulation.
Topics: Adult; Alleles; Asparagine; Body Mass Index; China; Cohort Studies; Female; Fertilization in Vitro; Follicle Stimulating Hormone; Genotype; Gonadotropins; Homozygote; Humans; Infertility, Female; Linkage Disequilibrium; Oocytes; Ovarian Hyperstimulation Syndrome; Ovary; Ovulation Induction; Polymorphism, Genetic; Receptors, FSH; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sperm Injections, Intracytoplasmic; Treatment Outcome; Young Adult | 2015 |
Metabolic profiling of synovial fluid in a unilateral ovine model of anterior cruciate ligament reconstruction of the knee suggests biomarkers for early osteoarthritis.
Topics: Animals; Anterior Cruciate Ligament Reconstruction; Asparagine; Biomarkers; Disease Models, Animal; Female; Glucose; Hydroxyproline; Isobutyrates; Knee Joint; Magnetic Resonance Spectroscopy; Metabolome; Osteoarthritis, Knee; Serine; Sheep; Synovial Fluid; Uridine | 2015 |
Microstructure and nanomechanical properties of enamel remineralized with asparagine-serine-serine peptide.
Topics: Adult; Asparagine; Dental Enamel; Durapatite; Humans; Models, Biological; Molar; Nanostructures; Oligopeptides; Saliva; Serine; Surface Properties; Tooth Remineralization | 2013 |
Structural modeling and patch-clamp analysis of pain-related mutation TRPA1-N855S reveal inter-subunit salt bridges stabilizing the channel open state.
Topics: Amino Acid Sequence; Animals; Asparagine; Calcium; Calcium Channels; Electric Stimulation; HEK293 Cells; Humans; Ion Channel Gating; Isothiocyanates; Membrane Potentials; Models, Molecular; Mutagenesis; Mutation; Nerve Tissue Proteins; Patch-Clamp Techniques; Protein Structure, Tertiary; Serine; Transfection; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2015 |
α-Thalassemia associated with hb instability: a tale of two features. the case of Hb Rogliano or α1 Cod 108(G15)Thr→Asn and Hb Policoro or α2 Cod 124(H7)Ser→Pro.
Topics: Adolescent; Adult; Aged; alpha-Thalassemia; Asparagine; Base Sequence; Child; DNA Mutational Analysis; Exons; Female; Genotype; Hemoglobins, Abnormal; Humans; Male; Middle Aged; Pedigree; Polymorphism, Single Nucleotide; Proline; Protein Stability; Protein Structure, Quaternary; Protein Structure, Tertiary; RNA, Messenger; Serine; Threonine; Young Adult | 2015 |
Chemiluminescence Detection of Serine, Proline, Glycine, Asparagine, Leucine, and Histidine by Using Corresponding Aminoacyl-tRNA Synthetases as Recognition Elements.
Topics: Amino Acyl-tRNA Synthetases; Asparagine; Biological Assay; Buffers; Glycine; Histidine; Humans; Leucine; Luminescence; Luminescent Measurements; Luminol; Proline; Sensitivity and Specificity; Serine; Solutions; Water | 2015 |
A Novel Multivariate Index for Pancreatic Cancer Detection Based On the Plasma Free Amino Acid Profile.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Amino Acids; Area Under Curve; Asparagine; Body Mass Index; Cross-Sectional Studies; Early Detection of Cancer; Fasting; Female; Histidine; Humans; Isoleucine; Japan; Male; Middle Aged; Pancreatic Neoplasms; Pancreatitis, Chronic; ROC Curve; Serine; Tryptophan; Young Adult | 2015 |
Rapidly Progressive Transthyretin-Mediated Amyloidosis in a Domino Liver Transplant Recipient of a Ser23Asn Donor.
Topics: Adult; Amyloid Neuropathies, Familial; Asparagine; Humans; Liver Transplantation; Male; Mutation; Prealbumin; Serine; Treatment Outcome | 2016 |
Crystal structure of the drug-resistant S31N influenza M2 proton channel.
Topics: Amantadine; Antiviral Agents; Asparagine; Crystallization; Crystallography, X-Ray; Drug Resistance, Viral; Gene Expression; Hydrogen Bonding; Influenza A virus; Models, Molecular; Mutation; Protein Binding; Protons; Serine; Viral Matrix Proteins | 2016 |
Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor.
Topics: Arginine; Asparagine; Aspartate-Ammonia Ligase; Biological Transport; Cell Line, Tumor; Cell Proliferation; Culture Media; Gene Expression Regulation, Neoplastic; Glutamine; HeLa Cells; Histidine; Humans; Mechanistic Target of Rapamycin Complex 1; Metabolic Networks and Pathways; Multiprotein Complexes; Nucleotides; Serine; Signal Transduction; TOR Serine-Threonine Kinases | 2016 |
Discovery of a potent and highly selective transforming growth factor β receptor-associated kinase 1 (TAK1) inhibitor by structure based drug design (SBDD).
Topics: Animals; Asparagine; Crystallography, X-Ray; Drug Design; Enzyme Assays; Humans; Hydrogen Bonding; MAP Kinase Kinase Kinases; Mice; Microsomes, Liver; Molecular Structure; Protein Kinase Inhibitors; Pyrimidinones; Serine; Solubility; Structure-Activity Relationship; Thiophenes; Tyrosine | 2016 |
Position 97 of HLA-B, a residue implicated in pathogenesis of ankylosing spondylitis, plays a key role in cell surface free heavy chain expression.
Topics: Aminopeptidases; Antigens, Surface; Asparagine; ATP-Binding Cassette Transporters; beta 2-Microglobulin; Flow Cytometry; HeLa Cells; HLA-B27 Antigen; HLA-B51 Antigen; HLA-B7 Antigen; Humans; Membrane Transport Proteins; Minor Histocompatibility Antigens; Mutation; Serine; Spondylitis, Ankylosing; Threonine; Transfection; Valine | 2017 |
High serine:glyoxylate aminotransferase activity lowers leaf daytime serine levels, inducing the phosphoserine pathway in Arabidopsis.
Topics: Arabidopsis; Asparagine; Cell Respiration; Metabolic Networks and Pathways; Phosphoserine; Photosynthesis; Plant Leaves; Plant Proteins; Serine; Transaminases; Transcription, Genetic | 2017 |
Mechanistic Insight from Calorimetric Measurements of the Assembly of the Binuclear Metal Active Site of Glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes.
Topics: Amino Acid Substitution; Asparagine; Bacterial Proteins; Binding Sites; Calorimetry; Catalytic Domain; Cobalt; Enterobacter aerogenes; Enzyme Activation; Hydrogen Bonding; Kinetics; Manganese; Mutation; Phosphoric Diester Hydrolases; Phosphorus; Recombinant Proteins; Serine; Thermodynamics; Titrimetry | 2017 |
N370S-GBA1 mutation causes lysosomal cholesterol accumulation in Parkinson's disease.
Topics: Asparagine; Autophagy; Beclin-1; Calnexin; Cholesterol; Endoplasmic Reticulum; Female; Fibroblasts; Glucosylceramidase; Golgi Apparatus; Humans; Lysosomal-Associated Membrane Protein 1; Lysosomes; Male; Models, Biological; Mutation; Oxidative Stress; Parkinson Disease; Serine; TOR Serine-Threonine Kinases; Transcription Factor CHOP | 2017 |
Cross-phenotype association mapping of the MHC identifies genetic variants that differentiate psoriatic arthritis from psoriasis.
Topics: Adolescent; Adult; Age of Onset; Alleles; Arthritis, Psoriatic; Asparagine; Case-Control Studies; Genotype; HLA-B27 Antigen; HLA-C Antigens; Humans; Major Histocompatibility Complex; Phenotype; Polymorphism, Single Nucleotide; Psoriasis; Serine; Young Adult | 2017 |
A single mutation in the prM protein of Zika virus contributes to fetal microcephaly.
Topics: Americas; Amino Acid Substitution; Animals; Asparagine; Cell Line, Tumor; Cricetinae; Disease Outbreaks; Humans; Incidence; Mice; Microcephaly; Mutation; Neural Stem Cells; Polynesia; Serine; Viral Envelope Proteins; Zika Virus; Zika Virus Infection | 2017 |
A Ser75-to-Asp phospho-mimicking mutation in Src accelerates ageing-related loss of retinal ganglion cells in mice.
Topics: Aging; Amino Acid Substitution; Animals; Apoptosis; Asparagine; Cell Count; Cell Survival; Mice; Mice, Knockout; Optic Nerve Diseases; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); Retinal Ganglion Cells; Serine | 2017 |
Structure of a serine-type glutathione S-transferase of Ceriporiopsis subvermispora and identification of the enzymatically important non-canonical residues by functional mutagenesis.
Topics: Amino Acids; Asparagine; Coriolaceae; Crystallography, X-Ray; Fungal Proteins; Glutathione; Glutathione Transferase; Ligands; Mutagenesis; Serine; Tyrosine | 2019 |
Alteration in NMDAR-related amino acids in first episode psychosis.
Topics: Asparagine; Chromatography, Liquid; Female; Glutamic Acid; Glutamine; Humans; Hydroxyproline; Male; Mass Spectrometry; Proline; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Young Adult | 2019 |
Roles of N-methyl-D-aspartate receptors and D-amino acids in cancer cell viability.
Topics: Alanine; Amino Acids; Asparagine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Humans; Memantine; Middle Aged; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate; Serine; Skin Neoplasms | 2020 |
Ser-653-Asn substitution in the acetohydroxyacid synthase gene confers resistance in weedy rice to imidazolinone herbicides in Malaysia.
Topics: Acetoin; Acetolactate Synthase; Amino Acid Substitution; Asparagine; Biological Assay; DNA Mutational Analysis; DNA, Plant; Enzyme Assays; Herbicide Resistance; Herbicides; Imidazoles; Lactates; Malaysia; Mutation; Niacin; Nicotinic Acids; Oryza; Plant Proteins; Plant Weeds; Seeds; Serine; Weed Control | 2020 |
Targeting Asparagine and Serine Metabolism in Germinal Centre-Derived B Cells Non-Hodgkin Lymphomas (B-NHL).
Topics: Asparagine; Humans; Lymphoma, Non-Hodgkin; Metabolomics; Serine | 2021 |
Commentary on Urinary l-erythro-β-hydroxyasparagine: a novel serine racemase inhibitor and substrate of the Zn2+-dependent d-serine dehydratase.
Topics: Asparagine; Hydro-Lyases; Racemases and Epimerases; Serine; Zinc | 2021 |
Plasma d-amino acids are associated with markers of immune activation and organ dysfunction in people with HIV.
Topics: Alanine; Amino Acids; Asparagine; Biomarkers; HIV Infections; Humans; Multiple Organ Failure; Proline; Serine | 2022 |
Gonadotropin receptor polymorphisms (FSHR N680S and LHCGR N312S) are not predictive of clinical outcome and live birth in assisted reproductive technology.
Topics: Aneuploidy; Asparagine; Chorionic Gonadotropin; Female; Follicle Stimulating Hormone; Humans; Live Birth; Luteinizing Hormone; Menotropins; Polymorphism, Single Nucleotide; Pregnancy; Receptors, FSH; Receptors, LH; Reproductive Techniques, Assisted; Retrospective Studies; Serine | 2022 |
Role of the gut-microbiota-metabolite axis in the rotenone model of early-stage Parkinson's Disease.
Topics: Alanine; Animals; Asparagine; Gastrointestinal Microbiome; Glutamine; Hydroxyproline; Methionine; Mice; Parkinson Disease; Rotenone; Serine; Threonine | 2022 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
Recent strains of influenza D virus create a new genetic cluster for European strains.
Topics: Alanine; Animals; Arginine; Asparagine; Aspartic Acid; Cattle; Cattle Diseases; Glycine; Nucleotides; Orthomyxoviridae; Orthomyxoviridae Infections; Phylogeny; Proline; Serine; Thogotovirus; Threonine; Valine | 2022 |
Discrimination of blood metabolomics profiles in neonates with idiopathic polyhydramnios.
Topics: Alanine; Asparagine; Aspartic Acid; Cesarean Section; Child; Chromatography, Liquid; Female; Glutamates; Homocysteine; Humans; Infant, Newborn; Phenylalanine; Polyhydramnios; Pregnancy; RNA, Transfer; Serine; Tandem Mass Spectrometry | 2023 |