serine has been researched along with arachidonic acid in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.44) | 18.7374 |
| 1990's | 12 (26.67) | 18.2507 |
| 2000's | 21 (46.67) | 29.6817 |
| 2010's | 6 (13.33) | 24.3611 |
| 2020's | 4 (8.89) | 2.80 |
| Authors | Studies |
|---|---|
| Dorman, RV; Hamm, TF | 1 |
| Bernstein, PR; Buckner, CK; Coursin, DB; Krell, RD; Laravuso, RB; Will, JA | 1 |
| Frasier-Scott, K; Hatzakis, H; Jones, CM; Seong, D; Wu, KK | 1 |
| Allen, KN | 1 |
| Alexander, RW; Rao, GN; Runge, MS | 1 |
| Abdullah, K; Cromlish, WA; Huang, Z; Kennedy, BP; Payette, P | 1 |
| Buchwald, AB; Kreuzer, H; Meyer, T; Unterberg, C | 1 |
| Gewert, K; Holst, E; Sundler, R; Svensson, U; Wijkander, J | 1 |
| Hebert, SC; Lerea, K; Macica, CM; Wang, W; Yang, Y | 1 |
| Babior, BM; Benna, JE; Faust, LP; Inanami, O; Johnson, JL; Park, JW | 1 |
| Kodama, H; Sagara, Y; Spirito, A; Sugahara, K; Zhang, J; Zhang, M | 1 |
| Emoto, K; Ikemoto, A; Kobayashi, T; Okuyama, H; Umeda, M; Watanabe, S | 1 |
| Caput, D; Escoubet, L; Ferrara, P; Pipy, B; Quartulli, F; Rey, A; Sozzani, P | 1 |
| Diehl, JA; Hannink, M; Hans, A; Shah, D; Sun, GY; Tong, W; Xu, J | 1 |
| Béguin, P; Carranza, ML; Favre, H; Féraille, E; Geering, K; Gonin, S; Martin, PY; Rousselot, M | 1 |
| Bonventre, JV; Gijón, MA; Leslie, CC; Siddiqi, AR; Spencer, DM | 1 |
| Dessen, A | 1 |
| de Corte, V; Gettemans, J; Merlevede, W; Vandekerckhove, J; Waelkens, E | 1 |
| Garavito, RM; Ginell, SL; Lakkides, KM; Malkowski, MG; Mulichak, AM; Rieke, CJ; Smith, WL; Thuresson, ED | 1 |
| Garavito, RM; Lakkides, KM; Malkowski, MG; Micielli, R; Rieke, CJ; Smith, WL; Thuresson, ED | 1 |
| Aebersold, R; Canaan, S; Gelb, MH; Harper, J; Hefner, Y; Malik, KU; Muthalif, MM; Parmentier, JH; Zhou, H | 1 |
| Rådmark, O; Steinhilber, D; Szellas, D; Werz, O | 1 |
| Kalgutkar, AS; Kiefer, JR; Kozak, KR; Kurumbail, RG; Marnett, LJ; Pawlitz, JL; Prusakiewicz, JJ; Rowlinson, SW; Stallings, WC | 1 |
| Boetticher, E; Lambertino, AT; Leff, AR; Liu, J; Meliton, AY; Munoz, NM; Myo, S; Myou, S; Xu, C; Zhu, X | 1 |
| Bae, DS; Bae, YS; Ha, KS; Lee, IH; Rhee, SG; Suh, PG; You, JO | 1 |
| Baudry, M; Chartier, E; Marineau, A; Martel, MA; Massicotte, G; Ménard, C; Valastro, B | 1 |
| Gamblin, TC; Rankin, CA; Sun, Q | 1 |
| Salati, LM; Szeszel-Fedorowicz, W; Talukdar, I | 1 |
| Kodama, H; Liu, G; Manabe, M; Song, SJ; Yagi-Chaves, SN; Yamashita, K | 1 |
| Hirabayashi, T; Murayama, T; Nakamura, H; Shimizu, M; Suganami, A; Tamura, Y | 1 |
| Brandes, L; Hatch, GM; Queen, G; Xu, FY | 1 |
| Hedrick, CC; Lee, J; Nadler, JL; Nagelin, MH; Srinivasan, S | 1 |
| Chen, SL; Cheng, HC; Ho, TC; Hsieh, JW; Lo, TH; Tsao, YP; Yang, YC | 1 |
| Chalimoniuk, M; Langfort, J; Stepień, A; Stolecka, A; Strosznajder, JB; Ziemińska, E | 1 |
| Kohan, AB; Salati, LM; Talukdar, I; Walsh, CM | 1 |
| Garcia, MC; Johnson, K; Olden, K; Roberts, JD; Williams, J | 1 |
| Combs, B; Gamblin, TC; Voss, K | 1 |
| Baran, CP; Kotha, SR; Malireddy, S; Marsh, CB; Nana-Sinkam, PS; Parinandi, NL; Patel, RB; Piper, MG; Romberger, D; Sliman, S; Wewers, MD; Zhao, L | 1 |
| Ahluwalia, A; Baker, MD; Bubb, KJ; Östman, J; Panayiotou, C; Priestley, JV; Wen, H | 1 |
| Bartlett, SG; Boeglin, WE; Brash, AR; Gilbert, NC; Neau, DB; Newcomer, ME; Rui, Z; Waight, MT | 1 |
| Backs, J; Fredman, G; Hellmann, J; Ozcan, L; Spite, M; Spolitu, S; Tabas, I | 1 |
| Ballerini, P; Bruno, A; Contursi, A; D'Agostino, I; Dovizio, M; Falcone, L; Fullone, R; Mucci, M; Patrignani, P; Sacco, A; Tacconelli, S; Zucchelli, M | 1 |
| Criscuolo, E; Fazio, D; Maccarrone, M | 1 |
| van der Stelt, M; van Zadelhoff, G | 1 |
| Wang, L; Wu, S; Yu, Z; Zhao, W | 1 |
2 review(s) available for serine and arachidonic acid
| Article | Year |
|---|---|
Aspirin--now we can see it.
Topics: Acetylation; Animals; Arachidonic Acid; Aspirin; Binding Sites; Computer Simulation; Cyclooxygenase Inhibitors; Flurbiprofen; Isoenzymes; Models, Molecular; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins H; Protein Binding; Serine; Sheep | 1995 |
Structure and mechanism of human cytosolic phospholipase A(2).
Topics: Arachidonic Acid; Binding Sites; Carboxylic Ester Hydrolases; Cytosol; Humans; Leukotrienes; Models, Molecular; Phospholipases A; Phospholipids; Prostaglandins; Protein Conformation; Serine; Substrate Specificity | 2000 |
43 other study(ies) available for serine and arachidonic acid
| Article | Year |
|---|---|
Arachidonic acid metabolism in gerbil cerebra: effects of ischemia and pentobarbital.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Brain Ischemia; Cerebral Cortex; Choline; Ethanolamines; Fatty Acids, Nonesterified; Gerbillinae; Inositol Phosphates; Male; Pentobarbital; Perfusion; Phospholipids; Serine; Triglycerides | 1990 |
Pharmacological evidence that human intralobar airways do not contain different receptors that mediate contractions to leukotriene C4 and leukotriene D4.
Topics: Arachidonic Acid; Arachidonic Acids; Borates; Chromones; Cysteine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Leukotriene E4; Lung; Muscle Contraction; Receptors, Cell Surface; Receptors, Leukotriene; Receptors, Prostaglandin; Regression Analysis; Serine; SRS-A | 1986 |
Influence of natural and recombinant interleukin 2 on endothelial cell arachidonate metabolism. Induction of de novo synthesis of prostaglandin H synthase.
Topics: 6-Ketoprostaglandin F1 alpha; Alanine; Arachidonic Acid; Arachidonic Acids; Blotting, Western; Chromatography, High Pressure Liquid; Cycloheximide; Cysteine; Dactinomycin; Endothelium, Vascular; Enzyme Induction; Epoprostenol; Humans; Interleukin-2; Molecular Weight; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Serine; Structure-Activity Relationship; Tissue Plasminogen Activator; von Willebrand Factor | 1988 |
Hydrogen peroxide activation of cytosolic phospholipase A2 in vascular smooth muscle cells.
Topics: Animals; Arachidonic Acid; Cytosol; Enzyme Activation; Hydrogen Peroxide; Male; Muscle, Smooth, Vascular; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Serine | 1995 |
Functional identification of the active-site nucleophile of the human 85-kDa cytosolic phospholipase A2.
Topics: Amino Acid Sequence; Animals; Arachidonic Acid; Base Sequence; Binding Sites; Cell Line; Chromatography, Affinity; Cytoplasm; Dinoprostone; Enzyme Inhibitors; gamma-Linolenic Acid; Humans; Immunoblotting; Molecular Sequence Data; Mutagenesis, Site-Directed; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Serine; Transfection | 1996 |
Accumulation of unphosphorylated calponin in the submembranous cytoskeletons of arachidonic acid-stimulated human platelets.
Topics: Actins; Arachidonic Acid; Calcium-Binding Proteins; Calponins; Cytoskeletal Proteins; Humans; Microfilament Proteins; Microscopy, Fluorescence; Muscle Proteins; Phosphorylation; Phosphotyrosine; Platelet Activation; Protein Binding; Serine; Stimulation, Chemical; Threonine | 1996 |
Multiple C-terminal serine phosphorylation accompanies both protein kinase C-dependent and -independent activation of cytosolic 85 kDa phospholipase A2 in macrophages.
Topics: Amino Acid Sequence; Animals; Arachidonic Acid; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Female; Fusobacterium nucleatum; Gardnerella vaginalis; Macrophages, Peritoneal; Mice; Mice, Inbred Strains; Molecular Sequence Data; Phospholipases A; Phospholipases A2; Phosphopeptides; Phosphorylation; Protein Kinase C; Serine; Tetradecanoylphorbol Acetate | 1997 |
Role of the NH2 terminus of the cloned renal K+ channel, ROMK1, in arachidonic acid-mediated inhibition.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Arachidonic Acid; Cell Line; Cloning, Molecular; Female; Ion Channel Gating; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Rats; Recombinant Proteins; Sequence Alignment; Serine; Transfection; Xenopus laevis | 1998 |
Activation of p47(PHOX), a cytosolic subunit of the leukocyte NADPH oxidase. Phosphorylation of ser-359 or ser-370 precedes phosphorylation at other sites and is required for activity.
Topics: Arachidonic Acid; Biological Transport; Cytosol; Enzyme Activation; Hematopoietic Stem Cells; Leukocytes; Lymphocytes; Mutation; NADPH Oxidases; Phosphoproteins; Phosphorylation; Recombinant Proteins; Serine | 1998 |
D-cystathionine ketimine and L-cystathionine ketimine enhance superoxide generation by human neutrophils in a different manner.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arachidonic Acid; Benzoquinones; Cystathionine; Enzyme Inhibitors; Genistein; Humans; Lactams, Macrocyclic; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Serine; Staurosporine; Stereoisomerism; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 1999 |
Effects of docosahexaenoic and arachidonic acids on the synthesis and distribution of aminophospholipids during neuronal differentiation of PC12 cells.
Topics: Animals; Anti-Bacterial Agents; Arachidonic Acid; Cell Differentiation; Cell Membrane; Cell Size; Docosahexaenoic Acids; Ethanolamine; Flow Cytometry; Hemolysin Proteins; Nerve Growth Factors; Neurons; PC12 Cells; Peptides; Peptides, Cyclic; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Rats; Serine; Trinitrobenzenesulfonic Acid; Tritium | 1999 |
IL-13 induces serine phosphorylation of cPLA2 in mouse peritoneal macrophages leading to arachidonic acid and PGE2 production and blocks the zymosan-induced serine phosphorylation of cPLA2 and eicosanoid production.
Topics: Animals; Arachidonic Acid; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cytosol; Dinoprostone; Female; Flavonoids; Interleukin-13; Lipoxygenase; Macrophages, Peritoneal; Mice; Phospholipases A; Phosphorylation; Precipitin Tests; Prostaglandin-Endoperoxide Synthases; Serine; Signal Transduction; Zymosan | 1999 |
Involvement of lipid mediators on cytokine signaling and induction of secretory phospholipase A2 in immortalized astrocytes (DITNC).
Topics: Animals; Arachidonic Acid; Astrocytes; Carbon Radioisotopes; Cell Line, Transformed; Cell Membrane Permeability; Ceramides; Diglycerides; DNA-Binding Proteins; Glycerophospholipids; Interleukin-1; Lysophosphatidylcholines; Lysophospholipids; NF-kappa B; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipase D; Phospholipases A; Phospholipases A2; Phosphorus Radioisotopes; Protein Binding; Rats; Serine; Signal Transduction; Sphingomyelin Phosphodiesterase; Sphingomyelins; Tumor Necrosis Factor-alpha | 1999 |
Is phosphorylation of the alpha1 subunit at Ser-16 involved in the control of Na,K-ATPase activity by phorbol ester-activated protein kinase C?
Topics: Animals; Arachidonic Acid; Biological Transport; Cell Membrane; Cell Membrane Permeability; COS Cells; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Mutagenesis; Ouabain; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Serine; Sodium-Potassium-Exchanging ATPase; Temperature; Transfection | 2000 |
Cytosolic phospholipase A2 is required for macrophage arachidonic acid release by agonists that Do and Do not mobilize calcium. Novel role of mitogen-activated protein kinase pathways in cytosolic phospholipase A2 regulation.
Topics: Animals; Anisomycin; Arachidonic Acid; Calcimycin; Calcium; Cytosol; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Ionophores; Macrophages; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; NADPH Oxidases; Okadaic Acid; Phospholipase D; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Synthesis Inhibitors; Serine; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 2000 |
A novel endogenous PP2C-like phosphatase dephosphorylates casein kinase II-phosphorylated Physarum fragmin.
Topics: Alkaline Phosphatase; Amino Acid Sequence; Animals; Arachidonic Acid; Carrier Proteins; Casein Kinase II; Chromatography, DEAE-Cellulose; Kinetics; Magnesium; Manganese; Microfilament Proteins; Molecular Sequence Data; Phosphoprotein Phosphatases; Physarum polycephalum; Protein Serine-Threonine Kinases; Serine; Substrate Specificity | 2000 |
Mutational and X-ray crystallographic analysis of the interaction of dihomo-gamma -linolenic acid with prostaglandin endoperoxide H synthases.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Binding Sites; Blotting, Western; COS Cells; Crystallography, X-Ray; DNA Mutational Analysis; Fatty Acids; Kinetics; Models, Molecular; Mutation; Oxygen; Peroxidase; Prostaglandin-Endoperoxide Synthases; Protein Binding; Protein Conformation; Serine; Substrate Specificity; Transfection; Valine | 2001 |
Structure of eicosapentaenoic and linoleic acids in the cyclooxygenase site of prostaglandin endoperoxide H synthase-1.
Topics: Arachidonic Acid; Binding Sites; Computer Simulation; Crystallography, X-Ray; Cyclooxygenase 1; Eicosapentaenoic Acid; Isoenzymes; Leucine; Linoleic Acid; Models, Molecular; Mutation; Oxidation-Reduction; Phenylalanine; Prostaglandin-Endoperoxide Synthases; Protein Conformation; Serine; Substrate Specificity; Valine | 2001 |
Functional interaction of calcium-/calmodulin-dependent protein kinase II and cytosolic phospholipase A(2).
Topics: Animals; Aorta; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cytosol; Gene Expression Regulation, Enzymologic; Humans; Male; Muscle, Smooth, Vascular; Norepinephrine; Phospholipases A; Phosphorylation; Protein Binding; Rabbits; Serine | 2001 |
Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2).
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcium; Enzyme Activation; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Neutrophils; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein Transport; Serine | 2002 |
A novel mechanism of cyclooxygenase-2 inhibition involving interactions with Ser-530 and Tyr-385.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arginine; Binding, Competitive; Cell Line; Crystallography, X-Ray; Cyclooxygenase 2; Diclofenac; Dose-Response Relationship, Drug; Enzyme Inhibitors; Insecta; Isoenzymes; Mice; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Piroxicam; Prostaglandin-Endoperoxide Synthases; Protein Binding; Serine; Sulfonamides; Time Factors; Tyrosine | 2003 |
Activation of group IV cytosolic phospholipase A2 in human eosinophils by phosphoinositide 3-kinase through a mitogen-activated protein kinase-independent pathway.
Topics: Arachidonic Acid; Cell Differentiation; Enzyme Activation; Eosinophils; Gene Products, tat; Group IV Phospholipases A2; Humans; Isoenzymes; Leukotriene C4; MAP Kinase Signaling System; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Kinase C; Recombinant Fusion Proteins; Serine; Transduction, Genetic; Tritium | 2003 |
AHNAK-mediated activation of phospholipase C-gamma1 through protein kinase C.
Topics: Animals; Arachidonic Acid; Blotting, Western; Bradykinin; Calcium; COS Cells; Enzyme Activation; Gene Library; Glutathione Transferase; Humans; Inositol Phosphates; Isoenzymes; Membrane Proteins; Mice; Microscopy, Fluorescence; Models, Biological; Neoplasm Proteins; NIH 3T3 Cells; Phospholipase C beta; Phospholipase C gamma; Phosphorylation; Plasmids; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Recombinant Fusion Proteins; RNA Interference; RNA, Small Interfering; Serine; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Type C Phospholipases; Tyrosine | 2004 |
AMPA receptor phosphorylation is selectively regulated by constitutive phospholipase A(2) and 5-lipoxygenase activities.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Binding Sites; Binding, Competitive; Calcium Signaling; Dose-Response Relationship, Drug; Endocytosis; Enzyme Inhibitors; Group VI Phospholipases A2; Hippocampus; Lipoxygenase Inhibitors; Male; Neurons; Phospholipases A; Phospholipases A2; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Serine; Synaptic Membranes; Synaptic Transmission | 2005 |
Pseudo-phosphorylation of tau at Ser202 and Thr205 affects tau filament formation.
Topics: Arachidonic Acid; Blotting, Western; Dose-Response Relationship, Drug; Microscopy, Electron, Transmission; Mutagenesis, Site-Directed; Neurofibrillary Tangles; Phosphorylation; Protein Processing, Post-Translational; Serine; Spectrometry, Fluorescence; tau Proteins; Threonine | 2005 |
Arachidonic acid inhibits the insulin induction of glucose-6-phosphate dehydrogenase via p38 MAP kinase.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Enzyme Activation; Enzyme Induction; Fatty Acids, Unsaturated; Gene Expression; Glucosephosphate Dehydrogenase; Hepatocytes; Insulin; Insulin Receptor Substrate Proteins; Male; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serine; Signal Transduction; Tumor Necrosis Factor-alpha | 2005 |
Effect of five triterpenoid compounds isolated from root bark of Aralia elata on stimulus-induced superoxide generation, tyrosyl or serine/threonine phosphorylation and translocation of p47(phox), p67(phox), and rac to cell membrane in human neutrophils.
Topics: Arachidonic Acid; Aralia; Cell Membrane; Cells, Cultured; Cytochromes c; Cytosol; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Plant Bark; rac GTP-Binding Proteins; Serine; Superoxides; Tetradecanoylphorbol Acetate; Threonine; Triterpenes; Tyrosine | 2006 |
Ser515 phosphorylation-independent regulation of cytosolic phospholipase A2alpha (cPLA2alpha) by calmodulin-dependent protein kinase: possible interaction with catalytic domain A of cPLA2alpha.
Topics: Amino Acid Substitution; Animals; Arachidonic Acid; Base Sequence; Benzylamines; Biological Transport, Active; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Catalytic Domain; Cell Line; Cytosol; DNA Primers; Enzyme Inhibitors; Group IV Phospholipases A2; Humans; Ionophores; Mice; Mutagenesis, Site-Directed; Phosphorylation; Recombinant Proteins; Serine; Signal Transduction; Sulfonamides | 2008 |
The phospholipidosis-lnducing potential of the chemopotentiating drug, N,N-Diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine (DPPE, tesmilifene) correlates with its stimulation of phosphatidylserine synthesis and exposure on the plasma membrane in MCF-7 breas
Topics: Antineoplastic Agents; Arachidonic Acid; Breast Neoplasms; Cell Line, Tumor; Cell Membrane; Drug Synergism; Female; Humans; Lipidoses; Phenyl Ethers; Phosphatidylserines; Phospholipids; Serine | 2007 |
12/15-Lipoxygenase activity increases the degradation of macrophage ATP-binding cassette transporter G1.
Topics: Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Arachidonic Acid; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Cell Line; Cholesterol, HDL; Down-Regulation; Linoleic Acid; Lipoproteins; Macrophages; Mice; Phosphorylation; Protein Processing, Post-Translational; RNA, Catalytic; RNA, Messenger; Serine; Swine; Time Factors; Transfection | 2008 |
Cytosolic phospholipase A2-{alpha} is an early apoptotic activator in PEDF-induced endothelial cell apoptosis.
Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; Arachidonic Acid; Burns, Chemical; Caspase 3; Cells, Cultured; Corneal Neovascularization; Disease Models, Animal; Endothelial Cells; Eye Burns; Eye Proteins; Group IV Phospholipases A2; Humans; Mice; Mice, Inbred BALB C; Nerve Growth Factors; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase Inhibitors; Phosphorylation; PPAR gamma; Protein Kinase Inhibitors; Recombinant Proteins; RNA Interference; Serine; Serpins; Signal Transduction; Time Factors; Tumor Suppressor Protein p53 | 2009 |
Involvement of multiple protein kinases in cPLA2 phosphorylation, arachidonic acid release, and cell death in in vivo and in vitro models of 1-methyl-4-phenylpyridinium-induced parkinsonism--the possible key role of PKG.
Topics: Animals; Arachidonic Acid; Calcium; Catalytic Domain; Cell Death; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; In Vitro Techniques; Mice; Mice, Inbred C57BL; Models, Biological; Nerve Degeneration; Nitric Oxide Synthase Type I; Parkinsonian Disorders; PC12 Cells; Phospholipases A2, Cytosolic; Protein Kinase C; Rats; Serine; Signal Transduction; Substantia Nigra | 2009 |
A role for AMPK in the inhibition of glucose-6-phosphate dehydrogenase by polyunsaturated fatty acids.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Arachidonic Acid; Fatty Acids, Unsaturated; Glucosephosphate Dehydrogenase; Hepatocytes; Insulin; Insulin Receptor Substrate Proteins; Male; Phosphorylation; Protein Kinases; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction | 2009 |
Arachidonic acid stimulates formation of a novel complex containing nucleolin and RhoA.
Topics: Amino Acid Substitution; Arachidonic Acid; Cell Adhesion; Cell Line; Cell Nucleus; Cytoplasm; Gene Silencing; Humans; Immunoprecipitation; Mutant Proteins; Nucleolin; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Protein Transport; Proteomics; Recombinant Fusion Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA-Binding Proteins; RNA, Small Interfering; Serine | 2011 |
Pseudohyperphosphorylation has differential effects on polymerization and function of tau isoforms.
Topics: Amino Acid Substitution; Arachidonic Acid; Aspartic Acid; Biopolymers; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mutagenesis, Site-Directed; Phosphorylation; Protein Isoforms; Serine; tau Proteins; Tauopathies; Threonine | 2011 |
Phospholipase A(2) activation by poultry particulate matter is mediated through extracellular signal-regulated kinase in lung epithelial cells: regulation of interleukin-8 release.
Topics: Animals; Arachidonic Acid; Blood Proteins; Bone Marrow Cells; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Gene Knockout Techniques; Humans; Interleukin-8; Lung; Macrophages; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Particulate Matter; Phospholipases A2; Phosphorylation; Poultry; Protein Transport; Serine; Time Factors | 2013 |
20-Hydroxyeicosatetraenoic acid (20-HETE) is a novel activator of transient receptor potential vanilloid 1 (TRPV1) channel.
Topics: Animals; Arachidonic Acid; Capsaicin; Female; Ganglia, Spinal; Gene Expression Regulation; Humans; Hydrogen-Ion Concentration; Hydroxyeicosatetraenoic Acids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neurons; Patch-Clamp Techniques; Serine; TRPV Cation Channels | 2012 |
Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663.
Topics: Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Humans; Lipoxins; Models, Molecular; Phosphorylation; Point Mutation; Serine | 2012 |
Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Nucleus; Cells, Cultured; Cytoplasm; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Female; Immunoblotting; Intracellular Signaling Peptides and Proteins; Leukotriene B4; Macrophages; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microscopy, Confocal; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Receptors, Formyl Peptide; Serine | 2014 |
Characterization of cyclooxygenase-2 acetylation and prostanoid inhibition by aspirin in cellular systems.
Topics: Acetylation; Amino Acid Sequence; Arachidonic Acid; Aspirin; Cell Line, Tumor; Chromatography, Liquid; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Epithelial Cells; Gene Expression; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-1beta; Lipopolysaccharides; Mass Spectrometry; Monocytes; Primary Cell Culture; Protein Processing, Post-Translational; Recombinant Proteins; Serine | 2020 |
Radiometric Assay of ABHD2 Activity.
Topics: Arachidonic Acid; Arachidonic Acids; Endocannabinoids; Glycerides; Glycerol; Lipase; Progesterone; Serine | 2023 |
Oxygenation of Anandamide by Lipoxygenases.
Topics: Alkadienes; Arachidonic Acid; Arachidonic Acids; Cytochromes; Endocannabinoids; Lipoxygenases; Monoacylglycerol Lipases; Polyunsaturated Alkamides; Prostaglandin-Endoperoxide Synthases; Serine | 2023 |
Dissecting the potential mechanism of antihypertensive effects of RVPSL on spontaneously hypertensive rats via widely targeted kidney metabolomics.
Topics: 3-Hydroxybutyric Acid; Animals; Antihypertensive Agents; Arachidonic Acid; Biomarkers; Blood Pressure; Carbon; Citric Acid; Hypertension; Kidney; Metabolomics; Rats; Rats, Inbred SHR; Serine; Thyronines; Tyramine; Tyrosine | 2023 |