serine has been researched along with 1-anilino-8-naphthalenesulfonate in 75 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (17.33) | 18.7374 |
| 1990's | 21 (28.00) | 18.2507 |
| 2000's | 27 (36.00) | 29.6817 |
| 2010's | 11 (14.67) | 24.3611 |
| 2020's | 3 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hirayama, O; Maenaka, K; Matsuda, H; Takatsuka, H; Takeda, H | 1 |
| Adhikari, HR; Tappel, AL | 1 |
| Aleman-Gomez, JA; Colwell, NS; Kumar, VB; Sasser, T | 1 |
| Lowe, ME | 1 |
| Hadváry, P; Lüthi-Peng, Q; Märki, HP | 1 |
| Derewenda, U; Derewenda, ZS | 1 |
| Hadváry, P; Meister, W; Sidler, W; Vetter, W; Wolfer, H | 1 |
| Feller, G; Gerday, C; Thiry, M | 1 |
| D'Arcy, A; Hunziker, W; Winkler, FK | 1 |
| Ameis, D; Davis, RC; Doolittle, MH; Schotz, MC; Stahnke, G; Will, H; Wong, H | 1 |
| Sidebottom, CM; Slabas, AR; Windust, J | 1 |
| Abouakil, N; Lombardo, D; Rogalska, E | 1 |
| Honda, H; Iwasaki, S; Kawaguchi, Y; Taniguchi-Morimura, J | 1 |
| Chou, WY; Matthews, KS | 1 |
| Aaviksaar, A; Osa, A; Sikk, P | 1 |
| Awad, WM; Bradley, S; Fulton, JE; Noble, NL | 1 |
| Huttunen, JK; Steinberg, D | 1 |
| Brockerhoff, H | 1 |
| Bianchetta, J; Guidoni, A; Rovery, M | 1 |
| Charles, M; Desnuelle, P; Maylié, MF | 1 |
| Jamieson, JD; Meldolesi, J; Palade, GE | 1 |
| Benkouka, F; De Caro, J; Guidoni, A; Rovery, M | 1 |
| Kunz, H; Schultz, M | 1 |
| Hirano, H; Kajiwara, H; Komatsu, S; Takagi, Y; Tsunasawa, S | 1 |
| Brumlik, MJ; Buckley, JT | 1 |
| Kupers, LP; Reekmans, G; Teuchy, HJ; Timmermans, MY | 1 |
| Laskowski, RA; Thornton, JM; Wallace, AC | 1 |
| Aisaka, K; Hirano, A; Shinkai, A | 1 |
| Chahrokh-Zadeh, S; Lohse, P; Seidel, D | 1 |
| Bruneau, N; Fisher, EA; Lombardo, D; Nganga, A | 1 |
| Egmond, MR; van Bemmel, CJ | 1 |
| Dekker, N; Egmond, MR; Simons, JW; van Kampen, MD; Verheij, HM | 1 |
| Fischer, M; Pleiss, J; Schmid, RD | 1 |
| Kinnunen, PK; Langberg, H; Patkar, SA; Peters, GH; Svendsen, A; Toxvaerd, S; Vind, J | 1 |
| Hult, K; Martinelle, M; Norin, T; Rotticci, D | 1 |
| Ebel, C; Madern, D; Mevarech, M; Pfister, C; Richard, SB; Zaccai, G | 1 |
| Adamo, G; Camardella, L; Carratore, V; Febbraio, F; Manco, G; Rossi, M | 1 |
| Jing, G; Yin, J | 1 |
| Dijkstra, BW; Jaeger, KE; Lang, DA; Liebeton, K; Nardini, M | 1 |
| Chang, TY; Lee, GC; Sun, GH; Sun, KH; Tang, SJ | 1 |
| Jaeger, KE; Liebeton, K; Zacharias, A | 1 |
| Kolattukudy, PE | 1 |
| Fransson, L; Hult, K; Raza, S | 1 |
| Chang, TY; Lee, GC; Lin, CK; Lo, YC; Shaw, JF; Sun, GH; Sun, KH; Tang, SJ | 1 |
| Bywater, RP; Peters, GH | 1 |
| Kauffmann, I; Schmidt-Dannert, C | 1 |
| Hermetter, A; Oskolkova, OV | 1 |
| Alam, M; Lehner, R; Vance, DE | 1 |
| Kawasaki, K; Kondo, H; Ohgiya, S; Suzuki, M; Tsuda, S | 1 |
| Masuda, T; Ohta, H; Shimada, H; Suzuki, T; Takamiya, K; Tsuchiya, T; Yamada, T | 1 |
| Berti-Dupuis, L; Carrière, F; Miled, N; Riviere, M; Verger, R | 1 |
| Kinoshita, T; Maeda, Y; Tanaka, S; Tashima, Y | 1 |
| McAuley, KE; Patkar, SA; Svendsen, A; Wilson, KS | 1 |
| Abramić, M; Allmaier, G; Kojić-Prodić, B; Lescić, I; Rizzi, A; Zehl, M | 1 |
| Igarashi, K; Kawano, K; Matsubara, K; Matsuura, A; Mizuguchi, M; Mori, Y; Saitoh, T; Shinoda, H; Shinohara, Y; Takeuchi, M | 1 |
| Attias, C; Carrière, F; Chahinian, H; Fojan, P; Petersen, SB; Snabe, T | 1 |
| Chang, SW; Lee, GC; Shaw, JF | 1 |
| Greenberg, AS; Kraemer, FB; Miyoshi, H; Obin, MS; Perfield, JW; Shen, WJ; Souza, SC; Stancheva, ZS; Zhang, HH | 1 |
| Bugg, TD; Li, JJ | 1 |
| Barends, TR; Blumenstein, L; Casino, P; Dunn, MF; Harris, R; Kimmich, N; Kulik, V; Ngo, H; Niks, D; Schlichting, I; Weyand, M | 1 |
| Ham, HJ; Rho, HJ; Shin, SK; Yoon, HJ | 1 |
| Ben Rebah, F; Chaâbouni, R; Fendri, A; Gargouri, Y; Miled, N; Smichi, N | 1 |
| Bustos-Jaimes, I; Calcagno, ML; Farrés, A; Mora-Lugo, R | 1 |
| Arner, P; Hedén, P; Kulyté, A; Lorente-Cebrián, S; Näslund, E; Rydén, M | 1 |
| Canny, BJ; Lee-Young, R; Mason, RR; Meex, RC; Watt, MJ | 1 |
| Gopalakrishna, KN; Kumar, PR; Prakash, V | 1 |
| An, J; Cui, L; Feng, Y; Wu, G; Xie, Y; Yang, G; Zhang, Y | 1 |
| Birner-Gruenberger, R; Boeszoermenyi, A; Brasaemle, DL; Carman, GM; Chang, YF; Cornaciu, I; Dinh, A; Fritz, K; McMahon, D; Montero-Moran, G; Oberer, M; Russell, D; Sahu-Osen, A; Schittmayer, M | 1 |
| Andreeva, TV; Ayvazyan, NM; Ghazaryan, NA; Ghulikyan, L; Kishmiryan, A; Lomonte, B; Tsetlin, VI; Utkin, YN | 1 |
| Anstadt, EJ; Cervantes, J; Clark, RB; Dewhirst, FE; Dietz, C; Finegold, S; Gallagher, JJ; Liu, Y; Nemati, R; Nichols, FC; Smith, MB; Yao, X | 1 |
| Leow, TC; Rahman, RNZRA; Salleh, AB; Sani, HA; Shariff, FM | 1 |
| Chopra, N; Kaur, J; Kumar, A | 1 |
| Boyko, KM; Dolgikh, DA; Kirpichnikov, MP; Korzhenevsky, DA; Kryukova, MV; Nikolaeva, AY; Novototskaya-Vlasova, KA; Petrovskaya, LE; Popov, VO; Rivkina, EM | 1 |
| James, JK; John, G; Marwaha, S; Nanda, V; Samateh, M | 1 |
| Criscuolo, E; Fazio, D; Maccarrone, M | 1 |
2 review(s) available for serine and 1-anilino-8-naphthalenesulfonate
| Article | Year |
|---|---|
Chemical and enzymatic synthesis of glycopeptides.
Topics: Amino Acid Sequence; Carbohydrate Sequence; Endopeptidases; Glycopeptides; Glycosylation; Glycosyltransferases; Lipase; Molecular Sequence Data; Oligosaccharides; Serine; Threonine | 1995 |
Polyesters in higher plants.
Topics: Carboxylic Ester Hydrolases; Cell Wall; Cinnamates; Dicarboxylic Acids; Fatty Acids; Fungi; Hydroxylation; Lipase; Lipids; Membrane Lipids; Models, Biological; Models, Chemical; Plant Proteins; Polyesters; Serine; Transcription, Genetic | 2001 |
73 other study(ies) available for serine and 1-anilino-8-naphthalenesulfonate
| Article | Year |
|---|---|
Purification and properties of a lipid acyl-hydrolase from potato tubers.
Topics: Binding Sites; Galactose; Glycerides; Glycolipids; Hydrogen-Ion Concentration; Kinetics; Lipase; Molecular Weight; Phosphatidylcholines; Phospholipids; Plants; Serine; Sulfhydryl Compounds; Tryptophan; Tyrosine | 1975 |
Letter: Flourescent products from irradiated amino acids and proteins.
Topics: Alcohol Oxidoreductases; Amino Acids; Amylases; Arginine; Bacteria; Cobalt Radioisotopes; Fluorescence; Fructose-Bisphosphate Aldolase; Gamma Rays; Glutamates; L-Lactate Dehydrogenase; Lipase; Methionine; Muramidase; Muscles; Ovalbumin; Phenylalanine; Proteins; Radiation Effects; Ribonucleases; Saccharomyces cerevisiae; Serine | 1975 |
Molecular cloning and characterization of rabbit pancreatic triglyceride lipase.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Lipase; Molecular Sequence Data; Open Reading Frames; Pancreas; Protein Sorting Signals; Rabbits; Sequence Homology, Amino Acid; Serine | 1992 |
The catalytic site residues and interfacial binding of human pancreatic lipase.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Codon; Humans; Kinetics; Lipase; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Pancreas; Polymerase Chain Reaction; Recombinant Proteins; Restriction Mapping; Serine; Transfection | 1992 |
Identification of the active-site serine in human pancreatic lipase by chemical modification with tetrahydrolipstatin.
Topics: Amino Acid Sequence; Binding Sites; Humans; Lactones; Lipase; Molecular Sequence Data; Orlistat; Pancreas; Serine; Spectrometry, Mass, Fast Atom Bombardment; X-Ray Diffraction | 1992 |
Relationships among serine hydrolases: evidence for a common structural motif in triacylglyceride lipases and esterases.
Topics: Amino Acid Sequence; Esterases; Glycine; Lipase; Molecular Sequence Data; Molecular Structure; Mucorales; Oligopeptides; Protein Conformation; Serine; Serine Endopeptidases; X-Ray Diffraction | 1991 |
The lipase inhibitor tetrahydrolipstatin binds covalently to the putative active site serine of pancreatic lipase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Esters; Lactones; Lipase; Molecular Sequence Data; Orlistat; Pancreas; Serine; Spectrometry, Mass, Fast Atom Bombardment; Swine | 1991 |
Nucleotide sequence of the lipase gene lip2 from the antarctic psychrotroph Moraxella TA144 and site-specific mutagenesis of the conserved serine and histidine residues.
Topics: Acclimatization; Amino Acid Sequence; Animals; Base Sequence; Biological Evolution; Cold Temperature; DNA, Bacterial; Genes, Bacterial; Histidine; Humans; Lipase; Molecular Sequence Data; Moraxella; Mutagenesis, Site-Directed; Protein Conformation; Restriction Mapping; Sequence Homology, Nucleic Acid; Serine | 1991 |
Structure of human pancreatic lipase.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Catalysis; DNA; Humans; Lipase; Molecular Sequence Data; Molecular Structure; Pancreas; Protein Conformation; Serine; X-Ray Diffraction | 1990 |
Hepatic lipase: site-directed mutagenesis of a serine residue important for catalytic activity.
Topics: Animals; Binding Sites; Esterases; Lipase; Liver; Male; Mutation; Oligonucleotide Probes; Oocytes; Rats; Restriction Mapping; RNA, Messenger; Serine; Xenopus laevis | 1990 |
Does sequence similarity of human choline esterase, Torpedo acetylcholine esterase and Geotrichum candidum lipase reveal the active site serine residue?
Topics: Acetylcholinesterase; Amino Acid Sequence; Animals; Binding Sites; Cholinesterases; Geotrichum; Humans; Lipase; Mitosporic Fungi; Molecular Sequence Data; Sequence Homology, Nucleic Acid; Serine; Torpedo | 1990 |
Human milk bile-salt stimulated lipase: further investigations on the amino-acids residues involved in the catalytic site.
Topics: Acylation; Adsorption; Bile Acids and Salts; Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Chemistry, Physical; Diethyl Pyrocarbonate; Histidine; Humans; Hydrogen Bonding; Isoflurophate; Isoxazoles; Kinetics; Lipase; Micelles; Milk, Human; Phosphorylation; Serine; Spectrophotometry; Structure-Activity Relationship | 1989 |
The codon CUG is read as serine in an asporogenic yeast Candida cylindracea.
Topics: Amino Acid Sequence; Base Sequence; Candida; Codon; DNA, Fungal; Genes; Genes, Fungal; Isoenzymes; Lipase; Molecular Sequence Data; RNA, Messenger; Saccharomyces cerevisiae; Serine | 1989 |
Serine to cysteine mutations in trp repressor protein alter tryptophan and operator binding.
Topics: Amino Acid Sequence; Anilino Naphthalenesulfonates; Bacterial Proteins; Binding Sites; Cysteine; Disulfides; DNA; Fluorescent Dyes; Molecular Sequence Data; Mutation; Naphthalenesulfonates; Operator Regions, Genetic; Repressor Proteins; Serine; Transcription Factors; Tryptophan | 1989 |
Irreversible inhibition of pancreatic lipase by bis-p-nitrophenyl methylphosphonate.
Topics: Animals; Binding Sites; Kinetics; Lipase; Organophosphorus Compounds; Pancreas; Serine; Swine; Tyrosine | 1985 |
The glycerol ester hydrolase (EC 3.1.1.3) from Corynebacterium acnes: a serine lipase.
Topics: Acetates; Acne Vulgaris; Binding Sites; Carbon Radioisotopes; Corynebacterium; Drug Stability; Female; Glycerides; Hot Temperature; Humans; Kinetics; Lipase; Male; Nitrobenzenes; Phosphorus Radioisotopes; Propionibacterium acnes; Protein Denaturation; Sebaceous Glands; Serine; Structure-Activity Relationship; Triglycerides; Triolein | 1974 |
Activation and phosphorylation of purified adipose tissue hormone-sensitive lipase by cyclic AMP-dependent protein kinase.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adipose Tissue; Animals; Cyclic AMP; Cyclic GMP; Cytosine Nucleotides; Enzyme Activation; Epididymis; Epinephrine; Guanosine Triphosphate; Hydrogen-Ion Concentration; Inosine Nucleotides; Kinetics; Lipase; Lumbosacral Region; Magnesium; Male; Muscles; Phosphoric Acids; Phosphorus Isotopes; Phosphotransferases; Protein Binding; Proteins; Rabbits; Rats; Rats, Inbred Strains; Serine; Time Factors; Uracil Nucleotides | 1971 |
A model of pancreatic lipase and the orientation of enzymes at interfaces.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Binding, Competitive; Chemical Phenomena; Chemistry; Histidine; Leucine; Lipase; Models, Chemical; Pancreas; Protein Binding; Protein Conformation; Serine | 1973 |
Chemical structure of porcine pancreatic lipase. End group determination and cyanogen bromide peptides.
Topics: Amino Acids; Animals; Chromatography, Gel; Cyanogen Bromide; Cystine; Electrophoresis, Disc; Isoenzymes; Kinetics; Lipase; Methionine; Pancreas; Peptides; Serine; Sodium Dodecyl Sulfate; Swine | 1973 |
Action of organophosphates and sulfonyl halides on porcine pancreatic lipase.
Topics: Amino Acid Sequence; Amino Acids; Animals; Bile Acids and Salts; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Dansyl Compounds; Histidine; Iodoacetates; Isoflurophate; Lipase; Nitrophenols; Pancreas; Peptides; Phosphoric Acids; Phosphorus Isotopes; Serine; Structure-Activity Relationship; Sulfonic Acids; Sulfur Isotopes; Tyrosine | 1972 |
Composition of cellular membranes in the pancreas of the guinea pig. II. Lipids.
Topics: Amino Alcohols; Animals; Biological Transport; Carbon Isotopes; Cell Membrane; Cholesterol; Chromatography, Gas; Chromatography, Thin Layer; Enzyme Precursors; Fatty Acids; Golgi Apparatus; Guinea Pigs; Histocytochemistry; Inositol; Lipase; Lipids; Lysophosphatidylcholines; Male; Microscopy, Electron; Microsomes; Microsomes, Liver; Monosaccharides; Pancreas; Phosphatidylcholines; Phospholipases; Serine; Serum Albumin, Bovine; Sphingomyelins; Triglycerides | 1971 |
Characterization of the serine reacting with diethyl p-nitrophenyl phosphate in porcine pancreatic lipase.
Topics: Adsorption; Amino Acid Sequence; Animals; Binding Sites; Lipase; Micelles; Pancreas; Paraoxon; Serine; Surface Properties; Swine | 1981 |
Microsequence analysis of the N-terminally blocked proteins immobilized on polyvinylidene difluoride membrane by western blotting.
Topics: Acetylation; Amino Acid Sequence; Animals; Blotting, Western; Cytochrome c Group; Geotrichum; Lipase; Membranes, Artificial; Microchemistry; Molecular Sequence Data; Peptide Fragments; Polyvinyls; Proteins; Pyrrolidonecarboxylic Acid; Sequence Analysis; Serine; Superoxide Dismutase; Threonine; Trypsin; Tryptophan Synthase | 1993 |
Identification of the catalytic triad of the lipase/acyltransferase from Aeromonas hydrophila.
Topics: Acyltransferases; Aeromonas hydrophila; Amino Acid Sequence; Aspartic Acid; Base Sequence; Binding Sites; Catalysis; DNA, Bacterial; Histidine; Lipase; Molecular Sequence Data; Mutagenesis, Site-Directed; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship | 1996 |
Inhibition studies on calf pregastric esterase: the enzyme has no functional thiol group.
Topics: Amino Acid Sequence; Animals; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Disulfides; Dithionitrobenzoic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kinetics; Lipase; Molecular Sequence Data; Molecular Weight; Paraoxon; Peptide Fragments; Pharynx; Pyridines; Serine | 1996 |
Derivation of 3D coordinate templates for searching structural databases: application to Ser-His-Asp catalytic triads in the serine proteinases and lipases.
Topics: Amino Acid Isomerases; Aspartic Acid; Bacterial Proteins; Binding Sites; Carrier Proteins; Databases, Factual; Histidine; Immunoglobulin G; Lipase; Peptide Fragments; Peptidylprolyl Isomerase; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Proteins; Sequence Analysis; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases; Templates, Genetic | 1996 |
Substitutions of Ser for Asn-163 and Pro for Leu-264 are important for stabilization of lipase from Pseudomonas aeruginosa.
Topics: Aspartic Acid; Enzyme Stability; Hydrogen-Ion Concentration; Leucine; Lipase; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Protein Conformation; Pseudomonas aeruginosa; Restriction Mapping; Serine | 1996 |
Human lysosomal acid lipase/cholesteryl ester hydrolase and human gastric lipase: identification of the catalytically active serine, aspartic acid, and histidine residues.
Topics: Animals; Aspartic Acid; Binding Sites; DNA, Complementary; Histidine; Humans; Hydrolysis; Lipase; Mutagenesis, Site-Directed; Rats; Serine; Substrate Specificity | 1997 |
O-Glycosylation of C-terminal tandem-repeated sequences regulates the secretion of rat pancreatic bile salt-dependent lipase.
Topics: Amino Acid Sequence; Animals; Brefeldin A; CHO Cells; Cricetinae; Cyclopentanes; DNA Probes; Galactose; Glutamic Acid; Glycosylation; Kinetics; Lipase; Monensin; Pancreas; Peptide Fragments; Proline; Rats; Recombinant Proteins; Serine; Sterol Esterase; Threonine; Transfection | 1997 |
Impact of structural information on understanding lipolytic function.
Topics: Binding Sites; Carboxylic Ester Hydrolases; Kinetics; Lipase; Lipolysis; Models, Structural; Protein Conformation; Protein Structure, Secondary; Pseudomonas; Serine | 1997 |
The phospholipase activity of Staphylococcus hyicus lipase strongly depends on a single Ser to Val mutation.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Lipase; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphates; Phospholipases; Phospholipids; Point Mutation; Sequence Homology, Amino Acid; Serine; Staphylococcus; Substrate Specificity; Valine | 1998 |
Anatomy of lipase binding sites: the scissile fatty acid binding site.
Topics: Animals; Bacterial Proteins; Binding Sites; Esterases; Fatty Acids; Fungal Proteins; Humans; Lipase; Protein Conformation; Serine; Substrate Specificity | 1998 |
Active serine involved in the stabilization of the active site loop in the Humicola lanuginosa lipase.
Topics: Alanine; Binding Sites; Dimyristoylphosphatidylcholine; Enzyme Stability; Lipase; Liposomes; Mitosporic Fungi; Models, Molecular; Mutagenesis, Site-Directed; Phosphatidylglycerols; Protein Structure, Secondary; Serine; Spectrometry, Fluorescence; Thermodynamics | 1998 |
An active-site titration method for lipases.
Topics: Binding Sites; Enzyme Inhibitors; Enzymes, Immobilized; Heptanes; Lipase; Serine; Solutions; Titrimetry; Water | 2000 |
Insights into the molecular relationships between malate and lactate dehydrogenases: structural and biochemical properties of monomeric and dimeric intermediates of a mutant of tetrameric L-[LDH-like] malate dehydrogenase from the halophilic archaeon Halo
Topics: Anilino Naphthalenesulfonates; Arginine; Dimerization; Enzyme Activation; Enzyme Stability; Haloarcula marismortui; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Malate Dehydrogenase; Mutagenesis, Site-Directed; Neutrons; Point Mutation; Protein Structure, Secondary; Scattering, Radiation; Serine; Sodium Chloride; Spectrometry, Fluorescence; Ultracentrifugation | 2000 |
Homology modeling and identification of serine 160 as nucleophile of the active site in a thermostable carboxylesterase from the archaeon Archaeoglobus fulgidus.
Topics: Affinity Labels; Amino Acid Sequence; Archaeoglobus fulgidus; Binding Sites; Carboxylic Ester Hydrolases; Computer Graphics; Enzyme Stability; Hot Temperature; Isoflurophate; Lipase; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Sequence Alignment; Serine; Thermodynamics | 2000 |
Tryptophan 140 is important, but serine 141 Is essential for the formation of the integrated conformation of staphylococcal nuclease.
Topics: Anilino Naphthalenesulfonates; Circular Dichroism; Fluorescent Dyes; Guanidine; Micrococcal Nuclease; Peptide Fragments; Protein Folding; Recombinant Proteins; Serine; Spectrometry, Fluorescence; Tryptophan | 2000 |
Crystal structure of pseudomonas aeruginosa lipase in the open conformation. The prototype for family I.1 of bacterial lipases.
Topics: Amino Acid Sequence; Binding Sites; Calcium; Catalysis; Crystallography, X-Ray; Disulfides; Lipase; Models, Molecular; Molecular Sequence Data; Multigene Family; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Pseudomonas aeruginosa; Sequence Homology, Amino Acid; Serine | 2000 |
Recombinant expression of the Candida rugosa lip4 lipase in Escherichia coli.
Topics: Candida; Codon; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fungal Proteins; Lipase; Mutagenesis, Site-Directed; Recombinant Fusion Proteins; Serine; Solubility; Substrate Specificity; Thioredoxins; Triglycerides | 2000 |
Disulfide bond in Pseudomonas aeruginosa lipase stabilizes the structure but is not required for interaction with its foldase.
Topics: Biological Transport; Cysteine; Disulfides; Enzyme Stability; Interleukin-6; Leukemia Inhibitory Factor; Lipase; Molecular Chaperones; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Folding; Proteins; Pseudomonas aeruginosa; Serine | 2001 |
Enantioselectivity in Candida antarctica lipase B: a molecular dynamics study.
Topics: Butanols; Candida; Caprylates; Fungal Proteins; Hexanols; Hydrolases; Hydrolysis; Lipase; Models, Chemical; Pentanols; Protein Binding; Serine; Software; Thermodynamics | 2001 |
Recombinant expression and characterization of the Candida rugosa lip4 lipase in Pichia pastoris: comparison of glycosylation, activity, and stability.
Topics: Candida; Carboxylic Ester Hydrolases; Codon; Enzyme Stability; Fungal Proteins; Glycosylation; Hot Temperature; Lipase; Pichia; Protein Processing, Post-Translational; Recombinant Proteins; Serine; Substrate Specificity | 2001 |
Influence of a lipid interface on protein dynamics in a fungal lipase.
Topics: Binding Sites; Computer Simulation; Crystallography, X-Ray; Hydrogen Bonding; Lipase; Lipids; Models, Molecular; Oxygen; Protein Binding; Protein Conformation; Protein Structure, Secondary; Proteins; Protons; Rhizomucor; Serine; Time Factors; Tryptophan | 2001 |
Conversion of Bacillus thermocatenulatus lipase into an efficient phospholipase with increased activity towards long-chain fatty acyl substrates by directed evolution and rational design.
Topics: Amino Acid Sequence; Bacillus; Binding Sites; Escherichia coli; Gene Library; Histidine; Leucine; Lipase; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Phospholipases; Plasmids; Protein Binding; Protein Conformation; Recombination, Genetic; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serine | 2001 |
Fluorescent inhibitors reveal solvent-dependent micropolarity in the lipid binding sites of lipases.
Topics: 2-Naphthylamine; Binding Sites; Burkholderia cepacia; Enzyme Inhibitors; Fluorescent Dyes; Lipase; Lipids; Molecular Structure; Naphthalenes; Nitrophenols; Organophosphonates; Protein Conformation; Rhizopus; Serine; Solvents; Spectrometry, Fluorescence | 2002 |
Structure-function analysis of human triacylglycerol hydrolase by site-directed mutagenesis: identification of the catalytic triad and a glycosylation site.
Topics: Animals; Catalytic Domain; Cells, Cultured; Escherichia coli; Glutamic Acid; Glycosylation; Histidine; Humans; Insecta; Lipase; Models, Molecular; Mutagenesis, Site-Directed; Recombinant Proteins; Serine; Structure-Activity Relationship | 2002 |
Alternate conformations observed in catalytic serine of Bacillus subtilis lipase determined at 1.3 A resolution.
Topics: Amino Acids; Bacillus subtilis; Binding Sites; Catalytic Domain; DNA; Histidine; Hydrogen Bonding; Lipase; Models, Chemical; Models, Molecular; Mutation; Protein Binding; Protein Conformation; Protein Folding; Serine; Substrate Specificity; X-Ray Diffraction | 2002 |
Chlorophyllase as a serine hydrolase: identification of a putative catalytic triad.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Carboxylic Ester Hydrolases; Catalysis; Chenopodium album; Enzyme Inhibitors; Histidine; Hydrolysis; Isoflurophate; Lipase; Molecular Sequence Data; Morpholines; Mutagenesis, Site-Directed; Mutation; p-Chloromercuribenzoic Acid; Phenylmethylsulfonyl Fluoride; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases | 2003 |
In vitro lipolysis by human pancreatic lipase is specifically abolished by its inactive forms.
Topics: Anthracenes; Bile Acids and Salts; Colipases; Enzyme Inhibitors; Enzyme Reactivators; Fluorescent Dyes; Glycine; Humans; In Vitro Techniques; Lipase; Lipolysis; Mutation; Organophosphorus Compounds; Pancreas; Pancreatic Juice; Recombinant Proteins; Serine | 2003 |
Inositol deacylation of glycosylphosphatidylinositol-anchored proteins is mediated by mammalian PGAP1 and yeast Bst1p.
Topics: Acylation; Amino Acid Sequence; Animals; CHO Cells; Cloning, Molecular; Consensus Sequence; Cricetinae; Fungal Proteins; Glycosylphosphatidylinositols; Humans; Inositol; Lipase; Mammals; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoric Monoester Hydrolases; Saccharomyces cerevisiae; Serine | 2004 |
Structure of a feruloyl esterase from Aspergillus niger.
Topics: Amino Acid Sequence; Aspartic Acid; Aspergillus niger; Bacterial Proteins; Binding Sites; Carboxylic Ester Hydrolases; Catalytic Domain; Coumaric Acids; Crystallography, X-Ray; Fungal Proteins; Histidine; Lipase; Models, Molecular; Molecular Sequence Data; Protein Conformation; Sequence Homology, Amino Acid; Serine; Structural Homology, Protein | 2004 |
Characterization of covalently inhibited extracellular lipase from Streptomyces rimosus by matrix-assisted laser desorption/ionization time-of-flight and matrix-assisted laser desorption/ionization quadrupole ion trap reflectron time-of-flight mass spectr
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Lipase; Molecular Sequence Data; Peptide Fragments; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Streptomyces | 2004 |
Dimeric transthyretin variant assembles into spherical neurotoxins.
Topics: Acrylamide; Amino Acid Substitution; Anilino Naphthalenesulfonates; Cell Death; Cell Line, Tumor; Chromatography, Gel; Dimerization; Genetic Variation; Humans; Isoleucine; Microscopy, Atomic Force; Nephelometry and Turbidimetry; Neuroblastoma; Neurotoxins; Prealbumin; Protein Binding; Protein Conformation; Protein Processing, Post-Translational; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Spectrometry, Fluorescence; Thermodynamics; Tryptophan | 2005 |
How gastric lipase, an interfacial enzyme with a Ser-His-Asp catalytic triad, acts optimally at acidic pH.
Topics: Animals; Aspartic Acid; Dogs; Histidine; Hydrogen-Ion Concentration; Kinetics; Lipase; Plants, Genetically Modified; Recombinant Proteins; Serine; Stomach; Zea mays | 2006 |
Efficient production of active recombinant Candida rugosa LIP3 lipase in Pichia pastoris and biochemical characterization of the purified enzyme.
Topics: Amino Acid Sequence; Base Sequence; Candida; Codon; DNA, Fungal; Enzyme Stability; Gene Expression; Isoenzymes; Lipase; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Pichia; Polymerase Chain Reaction; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Serine | 2006 |
Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes.
Topics: Adenoviridae; Adipocytes; Animals; Carboxylic Ester Hydrolases; Carrier Proteins; Cell Line; Cyclic AMP-Dependent Protein Kinases; Fibroblasts; Lipase; Lipolysis; Mice; Mice, Mutant Strains; Mutagenesis, Site-Directed; Perilipin-1; Phosphoproteins; Phosphorylation; Protein Structure, Tertiary; Serine | 2007 |
Investigation of a general base mechanism for ester hydrolysis in C-C hydrolase enzymes of the alpha/beta-hydrolase superfamily: a novel mechanism for the serine catalytic triad.
Topics: Benzoates; Binding Sites; Burkholderia; Catalysis; Escherichia coli; Escherichia coli Proteins; Esterases; Esters; Hydrogen-Ion Concentration; Hydrolases; Hydrolysis; Kinetics; Lipase; Nitrophenols; Serine; Substrate Specificity | 2007 |
Synthesis and characterization of allosteric probes of substrate channeling in the tryptophan synthase bienzyme complex.
Topics: Allosteric Regulation; Anilino Naphthalenesulfonates; Binding Sites; Glyceraldehyde 3-Phosphate; Glycerophosphates; Kinetics; Models, Chemical; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Salmonella typhimurium; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan Synthase | 2007 |
The TGL2 gene of Saccharomyces cerevisiae encodes an active acylglycerol lipase located in the mitochondria.
Topics: Alanine; Cerulenin; Fatty Acids; Fungal Proteins; Hydrolysis; Lipase; Lipids; Mitochondria; Mitosis; Mutation; Oleic Acid; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Saccharomyces cerevisiae; Serine; Substrate Specificity | 2010 |
Purification and biochemical characterization of an acid-stable lipase from the pyloric caeca of sardine (Sardinella aurita).
Topics: Acids; Ammonium Sulfate; Animals; Cecum; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Enzyme Activation; Enzyme Stability; Fishes; Hydrogen-Ion Concentration; Immunoblotting; Lactones; Lipase; Lipolysis; Orlistat; Pylorus; Serine; Temperature | 2010 |
Kinetic studies of Gly28:Ser mutant form of Bacillus pumilus lipase: changes in k(cat) and thermal dependence.
Topics: Algorithms; Amino Acid Sequence; Amino Acid Substitution; Bacillus; Bacterial Proteins; Biocatalysis; Cloning, Molecular; DNA, Bacterial; Enzyme Stability; Glycine; Kinetics; Lipase; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serine; Temperature | 2010 |
Relationship between site-specific HSL phosphorylation and adipocyte lipolysis in obese women.
Topics: Adipocytes; Adult; Cyclic AMP; Female; Humans; Lipase; Lipolysis; Middle Aged; Norepinephrine; Obesity; Phosphorylation; Protein Processing, Post-Translational; Serine; Sterol Esterase | 2011 |
Phosphorylation of adipose triglyceride lipase Ser(404) is not related to 5'-AMPK activation during moderate-intensity exercise in humans.
Topics: Adipose Tissue; Adult; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Blood Glucose; Cells, Cultured; Colforsin; Energy Metabolism; Exercise; Fatty Acids, Nonesterified; Humans; Lactic Acid; Lipase; Male; Muscle, Skeletal; Oxygen Consumption; Phosphorylation; Serine; Young Adult | 2012 |
Chemical modification of catalytic site of lipase from wheat germ: altered structure-activity profile.
Topics: Aspartic Acid; Calorimetry, Differential Scanning; Catalytic Domain; Circular Dichroism; Dose-Response Relationship, Drug; Histidine; Hot Temperature; Kinetics; Lipase; Protein Conformation; Protein Structure, Secondary; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Temperature; Triticum | 2002 |
Enhanced enzyme kinetic stability by increasing rigidity within the active site.
Topics: Calorimetry, Differential Scanning; Candida; Catalytic Domain; Crystallography, X-Ray; Enzyme Stability; Fungal Proteins; Gene Library; Hydrogen Bonding; Kinetics; Lipase; Molecular Dynamics Simulation; Mutagenesis; Protein Denaturation; Protein Engineering; Recombinant Proteins; Serine; Temperature; Thermodynamics | 2014 |
CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization.
Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Adipocytes; Amino Acid Sequence; Animals; Carrier Proteins; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Humans; Intracellular Space; Lipase; Male; Mice; Molecular Sequence Data; Perilipin-1; Phosphoproteins; Phosphorylation; Protein Binding; Protein Transport; Recombinant Proteins; Serine | 2015 |
Phospholipases a2 from Viperidae snakes: Differences in membranotropic activity between enzymatically active toxin and its inactive isoforms.
Topics: 2-Naphthylamine; Amino Acid Substitution; Anilino Naphthalenesulfonates; Animals; Aspartic Acid; Biological Transport; Brain Chemistry; Catalytic Domain; Fluorescent Dyes; Laurates; Lipid Bilayers; Lysine; Male; Membrane Fluidity; Phospholipases A2; Rats; Reptilian Proteins; Serine; Snake Venoms; Structure-Activity Relationship; Unilamellar Liposomes; Viperidae; Water | 2015 |
Deposition and hydrolysis of serine dipeptide lipids of Bacteroidetes bacteria in human arteries: relationship to atherosclerosis.
Topics: Atherosclerosis; Bacteroidetes; Brain; Carotid Arteries; Dipeptides; Humans; Hydrolysis; Lipase; Lipid Metabolism; Lipids; Serine | 2017 |
The Effects of One Amino Acid Substitutions at the C-Terminal Region of Thermostable L2 Lipase by Computational and Experimental Approach.
Topics: Amino Acid Substitution; Bacterial Proteins; Circular Dichroism; Enzyme Stability; Glutamic Acid; Isoleucine; Lipase; Molecular Dynamics Simulation; Protein Conformation; Recombinant Proteins; Serine; Temperature; Valine | 2018 |
Structural and functional insights into thermostable and organic solvent stable variant Pro247-Ser of Bacillus lipase.
Topics: Bacillus; Computational Biology; Enzyme Activation; Enzyme Stability; Enzymes, Immobilized; Gene Expression; Kinetics; Lipase; Molecular Dynamics Simulation; Protein Conformation; Protein Folding; Recombinant Proteins; Serine; Solvents; Structure-Activity Relationship; Substrate Specificity; Temperature | 2018 |
Crystal structure of PMGL2 esterase from the hormone-sensitive lipase family with GCSAG motif around the catalytic serine.
Topics: Amino Acid Motifs; Bacteria; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Lipase; Metagenome; Models, Molecular; Mutation; Permafrost; Protein Conformation; Protein Multimerization; Serine; Siberia; Substrate Specificity | 2020 |
Sucralose hydrogels: Peering into the reactivity of sucralose versus sucrose under lipase catalyzed trans-esterification.
Topics: Biocatalysis; Chlorine; Esterification; Food Additives; Hydrogels; Lipase; Oxygen; Serine; Sucrose; Water | 2022 |
Radiometric Assay of ABHD2 Activity.
Topics: Arachidonic Acid; Arachidonic Acids; Endocannabinoids; Glycerides; Glycerol; Lipase; Progesterone; Serine | 2023 |