seratrodast and thromboxane b2

seratrodast has been researched along with thromboxane b2 in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (61.54)18.2507
2000's4 (30.77)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arimura, A; Iwama, T; Koda, A; Kumimoto, M; Nagai, H; Yoshitake, K1
Imura, Y; Nishikawa, K; Terashita, Z1
Hada, S; Hashizume, M; Kurokawa, D; Nishii, S; Yasunaga, K; Yoshioka, F1
Granneman, GR; Hussein, Z; Locke, CS; Orchard, MA; Ringham, GL; Samara, E1
Asai, S; Kohno, S; Matsuo, N; Matsuse, H; Obase, Y; Shimoda, T1
Asai, S; Ayabe, H; Fukushima, C; Kohno, S; Matsuo, N; Matsuse, H; Obase, Y; Shimoda, T; Takao, A1
Killian, A; Walsh, SW; Wang, Y1
Abe, S; Igarashi, T; Kaneko, S; Miyazaki, N; Ohmichi, M; Saitoh, T; Tanaka, H; Teramoto, S1
Arakida, Y; Morio, H; Ohga, K; Okada, Y; Suwa, K; Yamada, T; Yokota, M1
Kotajima, R; Muramatsu, H; Sato, T1
Fukumoto, K; Hirose, M; Horiguchi, T; Kondo, R; Shiga, M; Tachikawa, S1
Dohi, S; Iida, H; Iida, M; Uchida, M1
An, J; Dong, JJ; Guo, LL; Li, JQ; Li, XO; Liao, ZL; Wan, C; Wang, T; Wen, FQ; Xu, D1

Trials

4 trial(s) available for seratrodast and thromboxane b2

ArticleYear
Characterization of the pharmacokinetics and pharmacodynamics of a new oral thromboxane A2-receptor antagonist AA-2414 in normal subjects: population analysis.
    Clinical pharmacology and therapeutics, 1994, Volume: 55, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Oral; Adolescent; Adult; Benzoquinones; Body Weight; Double-Blind Method; Heptanoic Acids; Humans; Leukotriene B4; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Quinones; Receptors, Thromboxane; Thromboxane A2; Thromboxane B2

1994
Effects of cysteinyl-leukotriene receptor antagonist, thromboxane A2 receptor antagonist, and thromboxane A2 synthetase inhibitor on antigen-induced bronchoconstriction in patients with asthma.
    Chest, 1998, Volume: 114, Issue:4

    Topics: Administration, Oral; Adult; Anti-Asthmatic Agents; Antigens; Asthma; Benzoquinones; Blood Proteins; Bronchial Provocation Tests; Bronchoconstriction; Chromones; Cross-Over Studies; Eosinophil Granule Proteins; Female; Follow-Up Studies; Heptanoic Acids; Histamine; Humans; Leukotriene Antagonists; Male; Membrane Proteins; Methacrylates; Receptors, Leukotriene; Receptors, Thromboxane; Ribonucleases; Thromboxane B2; Thromboxane-A Synthase; Treatment Outcome

1998
Can urinary eicosanoids be a potential predictive marker of clinical response to thromboxane A2 receptor antagonist in asthmatic patients?
    Respiratory medicine, 1999, Volume: 93, Issue:12

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Anti-Asthmatic Agents; Asthma; Benzoquinones; Creatinine; Eicosanoids; Female; Forced Expiratory Volume; Heptanoic Acids; Humans; Leukotriene E4; Male; Middle Aged; Peak Expiratory Flow Rate; Receptors, Thromboxane; Thromboxane B2

1999
Study on the usefulness of seratrodast in the treatment of chronic pulmonary emphysema.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:10

    Topics: Aged; Aged, 80 and over; Anti-Asthmatic Agents; Benzoquinones; Carbon Dioxide; Chronic Disease; Dyspnea; Female; Forced Expiratory Volume; Heptanoic Acids; Humans; Immunoglobulin E; Male; Middle Aged; Oxygen; Peak Expiratory Flow Rate; Prostaglandin Antagonists; Pulmonary Emphysema; Respiratory Function Tests; Smoking; Thromboxane A2; Thromboxane B2

2002

Other Studies

9 other study(ies) available for seratrodast and thromboxane b2

ArticleYear
The effect of three novel thromboxane A2 receptor antagonists (S-1452, AA-2414 and ONO-3708) on the increase in pulmonary pressure caused by Forssman anaphylaxis in guinea-pigs.
    Prostaglandins, leukotrienes, and essential fatty acids, 1992, Volume: 45, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Airway Resistance; Anaphylaxis; Animals; Antibodies, Heterophile; Benzoquinones; Bridged Bicyclo Compounds; Bronchoalveolar Lavage Fluid; Fatty Acids, Monounsaturated; Guinea Pigs; Heptanoic Acids; Histamine; Leukocyte Count; Male; Platelet Count; Quinones; Receptors, Prostaglandin; Receptors, Thromboxane; SRS-A; Thromboxane A2; Thromboxane B2

1992
The role of thromboxane (TX) A2 in rabbit arterial thrombosis induced by endothelial damage.
    Thrombosis research, 1990, Jul-01, Volume: 59, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Carotid Artery Thrombosis; Disease Models, Animal; Endothelium, Vascular; Fatty Acids, Monounsaturated; Heptanoic Acids; Male; Platelet Aggregation; Pyridines; Quinones; Rabbits; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase

1990
[Clinical study on the inhibitory effect of AA-2414 on platelet function in asthmatic patients].
    Arerugi = [Allergy], 1990, Volume: 39, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Asthma; Benzoquinones; Heptanoic Acids; Humans; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Quinones; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane B2

1990
In vitro responses to antigen stimulation: comparison between human lung parenchyma resected from asthmatic patients and non-asthmatic patients.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1999, Volume: 82, Issue:2

    Topics: Aged; Airway Resistance; Animals; Antigens; Ascaris; Asthma; Benzoquinones; Dinoprost; Dogs; Female; Heptanoic Acids; Histamine Release; Humans; Immune Sera; Immunization, Passive; Leukotrienes; Lung; Male; Middle Aged; Mites; Muscle Contraction; Muscle, Smooth; Radioallergosorbent Test; Smoking; Thromboxane B2; Thromboxane-A Synthase

1999
AA-2414, an antioxidant and thromboxane receptor blocker, completely inhibits peroxide-induced vasoconstriction in the human placenta.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Antioxidants; Benzoquinones; Blood Pressure; Dose-Response Relationship, Drug; Female; Fetus; Heptanoic Acids; Humans; In Vitro Techniques; Peroxides; Placenta; Pregnancy; Receptors, Thromboxane; Regional Blood Flow; Thromboxane B2; Vascular Resistance; Vasoconstriction

1999
Effect of combined leukotriene D(4) and thromboxane A(2) receptor antagonist on mediator-controlled resistance in guinea pigs.
    European journal of pharmacology, 2000, Sep-01, Volume: 403, Issue:1-2

    Topics: Administration, Oral; Airway Resistance; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Asthma; Benzoquinones; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Heptanoic Acids; Indomethacin; Leukotriene Antagonists; Leukotriene B4; Leukotriene C4; Leukotriene E4; Lipid Metabolism; Lung; Male; Membrane Proteins; Ovalbumin; Receptors, Leukotriene; Receptors, Thromboxane; Tetrazoles; Thiazoles; Thromboxane B2; Time Factors

2000
[Correlation between the clinical effects of Seratrodast and the level of 11-dehydrothromboxane B2 in urine/sputum in bronchial asthma patients].
    Arerugi = [Allergy], 2001, Volume: 50, Issue:6

    Topics: Adult; Aged; Anti-Asthmatic Agents; Asthma; Benzoquinones; Female; Heptanoic Acids; Humans; Male; Middle Aged; Prostaglandin Antagonists; Sputum; Thromboxane A2; Thromboxane B2

2001
Changes in cerebral microcirculation during and after abdominal aortic cross-clamping in rabbits: the role of thromboxane A2 receptor.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:3

    Topics: Animals; Aorta, Abdominal; Arterioles; Benzoquinones; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Constriction; Heart Rate; Hemodynamics; Heptanoic Acids; Hydrogen-Ion Concentration; Microcirculation; Prostaglandin Antagonists; Rabbits; Receptors, Thromboxane; Thromboxane B2

2003
Blocking of thromboxane A₂ receptor attenuates airway mucus hyperproduction induced by cigarette smoke.
    European journal of pharmacology, 2013, Mar-05, Volume: 703, Issue:1-3

    Topics: Animals; Anti-Asthmatic Agents; Benzoquinones; Bronchoalveolar Lavage Fluid; Heptanoic Acids; Lung; Male; Mitogen-Activated Protein Kinases; Mucin 5AC; Mucus; Nicotiana; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane A2, Prostaglandin H2; Smoke; Thromboxane B2

2013