seratrodast has been researched along with 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 6 (54.55) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ashida, Y; Fukumoto, S; Inada, Y; Shiraishi, M; Terashita, Z | 1 |
| Imura, Y; Inada, Y; Nishikawa, K; Shibouta, Y; Terashita, Z | 1 |
| Ashida, Y; Kato, K; Kuriki, H; Matsumoto, T; Shiraishi, M; Terao, S | 1 |
| Ashida, Y; Iwasa, S; Kurokawa, T; Matsumoto, T; Sasada, R | 1 |
| Granneman, GR; Hussein, Z; Locke, CS; Orchard, MA; Ringham, GL; Samara, E | 1 |
| Ashida, Y; Horiba, M; Itoh, Y; Kohno, S; Ohata, K; Shindoh, J; Takagi, K | 1 |
| Ashida, Y; Fukuda, S; Matsumoto, T; Nagaya, H; Nakayama, T; Yamasaki, M | 1 |
| Fujino, T; Kawabe, J; Kikuchi, K; Ohsaki, Y; Shiokoshi, T | 1 |
| Kohno, S; Mizutani, N; Nabe, T; Nakanishi, Y; Takenaka, H | 1 |
| Hiyama, Y; Ishimura, M; Kataoka, S; Maeda, T; Suda, M | 1 |
| Hiyama, Y; Ishimura, M; Kataoka, S; Kurokawa, S; Maeda, T; Morizumi, K; Suda, M | 1 |
1 trial(s) available for seratrodast and 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid
| Article | Year |
|---|---|
Characterization of the pharmacokinetics and pharmacodynamics of a new oral thromboxane A2-receptor antagonist AA-2414 in normal subjects: population analysis.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Oral; Adolescent; Adult; Benzoquinones; Body Weight; Double-Blind Method; Heptanoic Acids; Humans; Leukotriene B4; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Quinones; Receptors, Thromboxane; Thromboxane A2; Thromboxane B2 | 1994 |
10 other study(ies) available for seratrodast and 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid
| Article | Year |
|---|---|
Synthesis and thromboxane A2/prostaglandin H2 receptor antagonistic activity of phenol derivatives.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta; Benzoquinones; Blood Platelets; Bronchoconstriction; Cell Membrane; Fluorobenzenes; Guinea Pigs; Heptanoic Acids; Humans; Hydroquinones; Male; Molecular Structure; Muscle Contraction; Phenols; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Quinones; Rabbits; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1992 |
Antagonistic action of AA-2414 on thromboxane A2/prostaglandin endoperoxide receptor in platelets and blood vessels.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzoquinones; Blood Platelets; Dinoprost; Eicosanoids; Epoprostenol; Guinea Pigs; Heptanoic Acids; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Quinones; Rabbits; Receptors, Prostaglandin; Receptors, Thromboxane; Stereoisomerism; Swine | 1990 |
A novel anti-asthmatic quinone derivative, AA-2414 with a potent antagonistic activity against a variety of spasmogenic prostanoids.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Inhalation; Administration, Oral; Animals; Asthma; Benzoquinones; Dogs; Dose-Response Relationship, Drug; Guinea Pigs; Heptanoic Acids; Histamine Antagonists; Male; Platelet Activating Factor; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Quinones; Rabbits; Rats; Rats, Inbred Strains; SRS-A; Trachea | 1989 |
Antagonism of the human thromboxane A2 receptor by an anti-asthmatic agent AA-2414.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Asthma; Benzoquinones; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Guinea Pigs; Heptanoic Acids; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Plasmids; Prostaglandin Endoperoxides, Synthetic; Receptors, Thromboxane; Thromboxane A2; Trachea | 1994 |
[Inhibitory effects of AA-2414, a thromboxane (Tx) A2 receptor antagonist, on U-46619-, prostaglandin (PG) D2- and 9 alpha, 11 beta PGF2-induced contractions of guinea pig tracheas and isolated human bronchi].
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzoquinones; Bronchi; Dinoprost; Guinea Pigs; Heptanoic Acids; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Quinones; Receptors, Thromboxane; Thromboxane A2; Trachea | 1993 |
Involvement of thromboxane A2 and histamine in experimental allergic rhinitis of guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antigens; Benzoquinones; Capillary Permeability; Guinea Pigs; Heptanoic Acids; Histamine; Histamine H1 Antagonists; Male; Nasal Mucosa; Phthalazines; Prostaglandin Antagonists; Prostaglandin Endoperoxides, Synthetic; Rhinitis, Allergic, Seasonal; Thromboxane A2 | 1997 |
Downregulation of nitric oxide accumulation by cyclooxygenase-2 induction and thromboxane A2 production in interleukin-1beta-stimulated rat aortic smooth muscle cells.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta; Benzoquinones; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Down-Regulation; Enzyme Induction; Heptanoic Acids; Interleukin-1; Isoenzymes; Male; Membrane Proteins; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; RNA, Messenger; Thromboxane A2 | 2002 |
Synergism between cysteinyl leukotrienes and thromboxane A2 to induce allergic late phase nasal blockage in guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzoquinones; Chromones; Guinea Pigs; Heptanoic Acids; Hypersensitivity; Leukotriene D4; Leukotrienes; Male; Nasal Cavity; Thromboxane A2 | 2004 |
Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetates; Acetylcholine; Albuterol; Animals; Atropine; Benzoquinones; Carbachol; Chromones; Cyclopropanes; Dinoprost; Drug Evaluation, Preclinical; Guinea Pigs; Heptanoic Acids; Histamine; In Vitro Techniques; Indoles; Indomethacin; Ketanserin; Ketotifen; Leukotriene Antagonists; Leukotriene D4; Male; Muscle Contraction; Muscle, Smooth; Phenylcarbamates; Powders; Procaterol; Prostaglandin Antagonists; Prostaglandin D2; Quinolines; Receptors, Thromboxane A2, Prostaglandin H2; Serotonin; Substance P; Sulfides; Sulfonamides; Tosyl Compounds; Trachea; Tryptophan | 2006 |
Effects of KP-496, a novel dual antagonist at the cysteinyl leukotriene receptor 1 and the thromboxane A(2) receptor, on airway obstruction in guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetates; Administration, Inhalation; Administration, Oral; Airway Obstruction; Animals; Anti-Asthmatic Agents; Benzoates; Benzoquinones; Bronchoconstriction; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Guinea Pigs; Heptanoic Acids; Leukotriene Antagonists; Leukotriene D4; Lung; Male; Membrane Proteins; Ovalbumin; Prostaglandin Antagonists; Quinolines; Receptors, Leukotriene; Receptors, Thromboxane A2, Prostaglandin H2; Respiratory Hypersensitivity; Sulfides; Thiazoles; Time Factors | 2008 |