sepimostate mesilate has been researched along with gabexate in 3 studies
| Studies (sepimostate mesilate) | Trials (sepimostate mesilate) | Recent Studies (post-2010) (sepimostate mesilate) | Studies (gabexate) | Trials (gabexate) | Recent Studies (post-2010) (gabexate) |
|---|---|---|---|---|---|
| 27 | 4 | 1 | 743 | 53 | 106 |
| Protein | Taxonomy | sepimostate mesilate (IC50) | gabexate (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 2 | Homo sapiens (human) | 0.9 | |
| Coagulation factor X | Homo sapiens (human) | 4.61 | |
| Plasminogen | Homo sapiens (human) | 0.431 | |
| Urokinase-type plasminogen activator | Homo sapiens (human) | 0.431 | |
| Serine protease hepsin | Homo sapiens (human) | 0.383 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 0.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujii, S; Ino, Y; Iwaki, M; Kuramoto, S; Nakamura, K; Oda, M; Shimamura, K | 1 |
| Akizawa, Y; Ino, Y; Johmura, A; Kurumi, M; Miyazaki, H; Nakamura, K; Oda, M; Ohtani, H; Oka, T; Uchiyama, H | 1 |
| Fukui, K; Irimura, K; Oda, M; Oka, T; Yuasa, C | 1 |
3 other study(ies) available for sepimostate mesilate and gabexate
| Article | Year |
|---|---|
Pharmacological studies on 6-amidino-2-naphthyl[4-(4,5-dihydro-1H-imidazol-2-yl)amino] benzoate dimethane sulfonate (FUT-187). I: Inhibitory activities on various kinds of enzymes in vitro and anticomplement activity in vivo.
Topics: Amylases; Animals; Chymotrypsin; Complement Inactivator Proteins; Complement Pathway, Classical; Esters; Fibrinolysin; Forssman Antigen; Gabexate; Guanidines; Guinea Pigs; Hyaluronoglucosaminidase; Imidazoles; Lipase; Male; Phospholipases A; Protease Inhibitors; Serine Endopeptidases; Trypsin Inhibitors | 1990 |
[Inhibitory effects of sepimostat mesilate (FUT-187) on the activities of trypsin-like serine proteases in vitro].
Topics: Animals; Blood Coagulation; Esters; Gabexate; Guanidines; Guinea Pigs; Hemolysis; Humans; Imidazoles; In Vitro Techniques; Male; Rabbits; Rats; Rats, Sprague-Dawley; Serine Proteinase Inhibitors; Trypsin Inhibitors | 1995 |
Oral administration of sepimostat mesilate prevents acute alcohol pancreatic injury in rats.
Topics: Acute Disease; Administration, Oral; Amylases; Animals; Ceruletide; Esters; Ethanol; Gabexate; Guanidines; Imidazoles; Lipase; Male; Pancreas; Pancreatitis; Protease Inhibitors; Rats; Rats, Wistar | 1999 |