sepharose and lorazepam-acetate

sepharose has been researched along with lorazepam-acetate* in 1 studies

Other Studies

1 other study(ies) available for sepharose and lorazepam-acetate

Article	Year
Stereoselective allosteric binding interaction on human serum albumin between ibuprofen and lorazepam acetate. Chirality, 1999, Volume: 11, Issue:2 The effect of ibuprofen enantiomers on the stereoselective binding of 3-acyloxy-1,4-benzodiazepines to human serum albumin (HSA) was studied using both native and Sepharose-immobilized protein. (S)-Lorazepam acetate exhibited considerably enhanced binding, especially in the presence of (+)-(S)-ibuprofen. The phenomenon is an indication of cooperative allosteric interaction between different binding sites during multiple cobinding of two ligands. Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzodiazepines; Chromatography, Affinity; Chromatography, High Pressure Liquid; Humans; Ibuprofen; Lorazepam; Sepharose; Serum Albumin; Substrate Specificity; Ultrafiltration	1999

Article

Year

Stereoselective allosteric binding interaction on human serum albumin between ibuprofen and lorazepam acetate.

Chirality, 1999, Volume: 11, Issue:2

The effect of ibuprofen enantiomers on the stereoselective binding of 3-acyloxy-1,4-benzodiazepines to human serum albumin (HSA) was studied using both native and Sepharose-immobilized protein. (S)-Lorazepam acetate exhibited considerably enhanced binding, especially in the presence of (+)-(S)-ibuprofen. The phenomenon is an indication of cooperative allosteric interaction between different binding sites during multiple cobinding of two ligands.

Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzodiazepines; Chromatography, Affinity; Chromatography, High Pressure Liquid; Humans; Ibuprofen; Lorazepam; Sepharose; Serum Albumin; Substrate Specificity; Ultrafiltration

1999