senktide has been researched along with sb 222200 in 16 studies
| Studies (senktide) | Trials (senktide) | Recent Studies (post-2010) (senktide) | Studies (sb 222200) | Trials (sb 222200) | Recent Studies (post-2010) (sb 222200) |
|---|---|---|---|---|---|
| 292 | 1 | 50 | 60 | 0 | 25 |
| Protein | Taxonomy | senktide (IC50) | sb 222200 (IC50) |
|---|---|---|---|
| Neuromedin-K receptor | Homo sapiens (human) | 0.0089 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 8 (50.00) | 29.6817 |
| 2010's | 7 (43.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ames, RS; Brawner, ME; Buckley, PT; Elshourbagy, NA; Feild, JA; Foley, JJ; Giardina, GA; Hay, DW; Luttmann, MA; Nuthulaganti, P; Sarau, HM; Schmidt, DB | 1 |
| Griswold, DE; Hay, DW; Martin, LD; Medhurst, AD; Parsons, AA | 1 |
| Barone, FC; Bush, B; Foley, JJ; Giardina, GA; Griswold, DE; Hay, DW; Legos, JJ; Lundberg, D; Luttmann, MA; Martin, LD; Medhurst, AD; Potts, W; Sandhu, P; Sarau, HM; Schmidt, DB; Webb, EF; Whitmore, RG | 1 |
| Coupar, IM; Kerr, KP; Thai, B | 1 |
| Aggio, A; Carnicelli, V; Ciccocioppo, R; Onori, L; Severi, C; Taddei, G; Tonini, M | 1 |
| Howe, HE; Sladek, CD; Somponpun, SJ | 1 |
| Andren, PE; Chergui, K; Svenningsson, P; Zhang, X | 1 |
| Medd, AM; Simmons, MA; Sobotka-Briner, CD | 1 |
| Bassi, GS; Brandão, ML; Broiz, AC; Gomes, MZ | 1 |
| Ali, B; Amin, NA; Ciofi, P; Plant, TM; Ramaswamy, S; Seminara, SB | 1 |
| Dhillo, WS; Jayasena, CN | 1 |
| Couture, R; De Brito Gariepy, H | 1 |
| Boehm, U; de Croft, S; Herbison, AE | 1 |
| Grachev, P; Hu, MH; Li, SY; Li, XF; Lightman, SL; Millar, RP; O'Byrne, KT | 1 |
| Goodman, RL; Hardy, SL; Hileman, SM; Lehman, MN; Nestor, CC; Porter, KL | 1 |
| Garcia, JP; Guerriero, KA; Keen, KL; Kenealy, BP; Seminara, SB; Terasawa, E | 1 |
16 other study(ies) available for senktide and sb 222200
| Article | Year |
|---|---|
Molecular and pharmacological characterization of the murine tachykinin NK(3) receptor.
Topics: Amino Acid Sequence; Animals; Calcium; Cloning, Molecular; Humans; Mice; Molecular Sequence Data; Neurokinin A; Quinolines; Receptors, Neurokinin-3 | 2001 |
In vitro and in vivo characterization of NK3 receptors in the rabbit eye by use of selective non-peptide NK3 receptor antagonists.
Topics: Animals; In Vitro Techniques; Iris; Male; Miosis; Muscle Contraction; Muscle, Smooth; Neurokinin B; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Quinolines; Rabbits; Receptors, Neurokinin-3; Substance P | 1997 |
Nonpeptide tachykinin receptor antagonists. II. Pharmacological and pharmacokinetic profile of SB-222200, a central nervous system penetrant, potent and selective NK-3 receptor antagonist.
Topics: Animals; Brain; Calcium; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Iris; Male; Mice; Mice, Inbred BALB C; Peptide Fragments; Quinolines; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-3; Substance P | 2000 |
Tachykinin-induced contraction of the guinea-pig isolated oesophageal mucosa is mediated by NK(2) receptors.
Topics: Animals; Benzamides; Captopril; Dose-Response Relationship, Drug; Esophagus; Guinea Pigs; In Vitro Techniques; Mucous Membrane; Muscle Contraction; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Protease Inhibitors; Quinolines; Quinuclidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Tachykinins; Thiorphan | 2000 |
Contribution of NK3 tachykinin receptors to propulsion in the rabbit isolated distal colon.
Topics: Animals; Colon; Complement C6; Dose-Response Relationship, Drug; Gastrointestinal Motility; In Vitro Techniques; Male; Peptide Fragments; Piperidines; Quinolines; Rabbits; Receptors, Neurokinin-3; Substance P | 2001 |
Role of neurokinin 3 receptors in supraoptic vasopressin and oxytocin neurons.
Topics: Acetates; Animals; Catecholamines; Cell Compartmentation; Cell Nucleus; Cytoplasm; Endosomes; Hydralazine; Hypotension; Hypothalamo-Hypophyseal System; Hypothalamus, Anterior; Male; Microinjections; Microscopy, Confocal; Neurons; Oxytocin; Peptide Fragments; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P; Tachykinins; Transcription, Genetic; Tryptophan; Vasopressins | 2004 |
Neurokinin B/NK3 receptors exert feedback inhibition on L-DOPA actions in the 6-OHDA lesion rat model of Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Autoradiography; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cocaine; Disease Models, Animal; Dopamine; Feedback; Functional Laterality; Gene Expression Regulation; Levodopa; Oxidopamine; Parkinson Disease; Peptide Fragments; Quinolines; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-3; Serine; Substance P; Sympatholytics; Tyrosine 3-Monooxygenase | 2008 |
Localization and function of NK(3) subtype tachykinin receptors of layer V pyramidal neurons of the guinea-pig medial prefrontal cortex.
Topics: Animals; Autoradiography; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Guinea Pigs; In Vitro Techniques; Iodine Isotopes; Male; Membrane Potentials; Neurokinin B; Patch-Clamp Techniques; Peptide Fragments; Prefrontal Cortex; Protein Binding; Pyramidal Cells; Quinolines; Quinoxalines; Receptors, Neurokinin-3; Substance P; Valine | 2008 |
Evidence for mediation of nociception by injection of the NK-3 receptor agonist, senktide, into the dorsal periaqueductal gray of rats.
Topics: Animals; Anxiety; Exploratory Behavior; Fear; Male; Maze Learning; Microinjections; Motor Activity; Pain Measurement; Peptide Fragments; Periaqueductal Gray; Quinolines; Rats; Rats, Wistar; Receptors, Neurokinin-3; Substance P; Ultrasonics; Vocalization, Animal | 2009 |
Neurokinin B stimulates GnRH release in the male monkey (Macaca mulatta) and is colocalized with kisspeptin in the arcuate nucleus.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Drug Interactions; Gonadotropin-Releasing Hormone; Humans; Immunohistochemistry; Injections, Intravenous; Kisspeptins; Luteinizing Hormone; Macaca mulatta; Male; Microscopy, Confocal; Neurokinin B; Oligopeptides; Orchiectomy; Peptide Fragments; Quinolines; Receptors, G-Protein-Coupled; Receptors, LHRH; Receptors, Neurokinin-3; Substance P | 2010 |
Neurokinin B and kisspeptin: sexual partners or single agents?
Topics: Animals; Arcuate Nucleus of Hypothalamus; Drug Interactions; Gonadotropin-Releasing Hormone; Kisspeptins; Luteinizing Hormone; Macaca mulatta; Male; Neurokinin B; Oligopeptides; Orchiectomy; Peptide Fragments; Quinolines; Receptors, G-Protein-Coupled; Receptors, Neurokinin-3; Substance P | 2010 |
Blockade of tachykinin NK3 receptor reverses hypertension through a dopaminergic mechanism in the ventral tegmental area of spontaneously hypertensive rats.
Topics: Animals; Benzazepines; Blood Pressure; Dopamine; Haloperidol; Heart Rate; Hypertension; Ibotenic Acid; Indoles; Male; Oligopeptides; Peptide Fragments; Quinolines; Raclopride; Rats; Rats, Inbred SHR; Receptors, Neurokinin-3; Substance P; Ventral Tegmental Area | 2010 |
Neurokinin B activates arcuate kisspeptin neurons through multiple tachykinin receptors in the male mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Arcuate Nucleus of Hypothalamus; Dynorphins; Green Fluorescent Proteins; Kisspeptins; Male; Membrane Potentials; Mice; Mice, Transgenic; Neurokinin B; Neurons; Oligopeptides; Patch-Clamp Techniques; Peptide Fragments; Piperidines; Quinolines; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Opioid, kappa; Receptors, Tachykinin; Substance P | 2013 |
Neurokinin B signaling in the female rat: a novel link between stress and reproduction.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arcuate Nucleus of Hypothalamus; Corticosterone; Corticotropin-Releasing Hormone; Female; Gonadotropin-Releasing Hormone; Injections, Intraventricular; Lipopolysaccharides; Luteinizing Hormone; Neurokinin B; Neurons; Ovariectomy; Peptide Fragments; Pyrimidines; Pyrroles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Receptors, Neurokinin-3; Receptors, Vasopressin; Reproduction; Signal Transduction; Stress, Physiological; Substance P | 2014 |
Neurokinin-3 receptor activation in the retrochiasmatic area is essential for the full pre-ovulatory luteinising hormone surge in ewes.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Female; Hypothalamus; Luteinizing Hormone; Neurons; Ovulation; Peptide Fragments; Preoptic Area; Quinolines; Receptors, Neurokinin-3; Sheep; Substance P | 2014 |
Kisspeptin and Neurokinin B Signaling Network Underlies the Pubertal Increase in GnRH Release in Female Rhesus Monkeys.
Topics: Animals; Female; Gonadotropin-Releasing Hormone; Kisspeptins; Macaca mulatta; Median Eminence; Neurokinin B; Neurons; Peptide Fragments; Quinolines; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, Neurokinin-3; Sexual Maturation; Signal Transduction; Substance P | 2017 |