semustine has been researched along with lomustine in 75 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 67 (89.33) | 18.7374 |
1990's | 3 (4.00) | 18.2507 |
2000's | 4 (5.33) | 29.6817 |
2010's | 1 (1.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Clayton, SD; Frye, JL; Johnston, TP; Krauth, CA; McCaleb, GS; Montgomery, JA | 1 |
Johnston, TP; Laster, WR; Mayo, JG; McCaleb, GS; Montgomery, JA | 1 |
Hansch, C; Jow, PY; Leo, A; Montgomery, JA; Schmidt, C | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Barranco, SC; Gee, EL; Haenelt, BR | 1 |
Walker, MD | 2 |
Eisenbrand, G; Fiebig, HH; Zeller, WJ | 1 |
Bono, VH | 1 |
Livingston, RB | 1 |
Bonadonna, G; Brambilla, C; Monfardini, S; Morello, G; Solero, CL; Vaghi, A; Valagussa, P | 1 |
Hrushesky, WJ; Murphy, GP | 1 |
Burningham, RA; Carey, R; Cornell, CJ; Glidewell, O; Holland, JF; Jacquillat, C; Maurice, P; Nissen, NI; Pas, AT; Silver, RT | 1 |
Auletta, AE; Martz, AG; Parmar, AS | 1 |
Blessing, JA; Boronow, RC; Creasman, WT; Omura, GA; Shingleton, HM | 1 |
Hasegawa, H; Posner, JB; Shapiro, WR | 1 |
Corbett, TH; Griswold, DP; Schabel, FM; Venditti, JM; Wolpert, MK | 1 |
Laster, WR; Rose, WC; Schabel, FM; Veras, GH | 1 |
Barranco, SC; Bolton, WE; Novak, JK | 1 |
Athlin, L; Berghem, L; Domellöf, L | 1 |
Bono, VH; Louie, AC; Muggia, FM; Turrisi, AT | 1 |
Schabel, FM | 1 |
Ahmann, DL | 1 |
Wolf, J | 1 |
Douglass, HO; Lavin, PT; Moertel, CG | 1 |
Bartolucci, A; Dorfman, RF; Durant, JR; Gams, RA; Velez-Garcia, E | 1 |
Levin, VA; Wilson, CB | 2 |
Oliverio, VT | 1 |
Day, A; Liberman, L; Ng, R; Tator, CH | 1 |
Posner, JB; Shapiro, WR; Ushio, Y | 1 |
Blessing, J; Boronow, R; DiSaia, P; Hreshchyshyn, M; Omura, G; Park, R | 1 |
Moertel, CG | 1 |
Wasserman, TH | 1 |
Hilton, J; Walker, MD | 1 |
Hahn, RG; Moertel, CG; Reitemeier, RJ; Schutt, AJ | 1 |
Balis, E; Brisman, R; Chang, C; Duffy, P; Housepian, EM | 1 |
Slavik, M | 1 |
Carter, SK | 1 |
Drewinko, B; Gottlieb, JA; Loo, TL | 1 |
Camus, P; Coudert, B; Foucher, P; Jeannin, L; Lombard, JN; Massin, F; Reybet-Degat, O | 1 |
Anderson, SP; Briscoe, WT; May, HE | 1 |
Bodell, WJ; Doane-Setzer, P; Evans, CG; Smith, MT; Tokuda, K | 1 |
Giles, RC; Harrison, SD; Mann, DM | 1 |
Holden, SA; Rose, CM; Teicher, BA | 1 |
Ozhiganov, EL; Platinskiĭ, LV; Sokolova, VD | 1 |
Adams, K; Peacock, JH; Stephens, TC | 1 |
Heim, ME; Queisser, W | 1 |
Wakui, A | 1 |
Glatte, P; Osieka, R; Pannenbäcker, R; Schmidt, CG | 1 |
Lee, FY; Workman, P | 1 |
Schmidt, JD | 1 |
Higgins, GA | 1 |
Oguro, M; Takenaga, K; Yanagawa, T | 1 |
Johnston, TP; McCaleb, GS; Montgomery, JA; Rose, WC | 1 |
Levin, W; Potter, DW; Reed, DJ; Ryan, DE; Thomas, PE | 1 |
Shapiro, WR | 1 |
Robak, T | 1 |
Gropp, C; Havemann, K | 1 |
Deen, DF; Weinkam, RJ | 1 |
Cheung, LK; Smith, RG | 1 |
Berger, M; Zeller, WJ | 1 |
Kantor, P; Murphy, GP; Williams, PD | 1 |
Chauhan, SM; Lown, JW | 1 |
Blackstock, SC; Cheung, LK; Loo, TL; Smith, RG | 1 |
Baldwin, DS; Feiner, HD; Gallo, GR; Lieberman, A; Schacht, RG | 1 |
Eisenbrand, G; Habs, M | 1 |
Finn, A; Kane, JP; Levin, VA; Weinkam, RJ | 1 |
Finkel, JM; Hill, DL; Kari, P; McConnell, WR | 1 |
Cenci, E; Perito, S; Sbaraglia, G; Vecchiarelli, A | 1 |
Coates, AS; Segelov, E | 1 |
Penketh, PG; Sartorelli, AC; Shyam, K | 1 |
Guo, Y; Hong, X; Li, J; Li, X; Lu, JJ; Ma, X; Wang, B | 1 |
Kobiakov, GL | 1 |
Agarwal, S; Chadha, D; Mehrotra, R | 1 |
11 review(s) available for semustine and lomustine
Article | Year |
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Review of mechanism of action studies of the nitrosoureas.
Topics: Alkylating Agents; Animals; Bone Marrow; Bone Marrow Cells; Carmustine; Cell Division; Cell Survival; DNA; DNA, Neoplasm; Ethyl Chloride; Lomustine; Mice; NAD+ Nucleosidase; Neoplasms, Experimental; Nitrosourea Compounds; Protein Biosynthesis; RNA; Semustine; Streptozocin | 1976 |
Current status of the therapy of advanced renal carcinoma.
Topics: Adenocarcinoma; Androgens; Animals; Antineoplastic Agents; Drug Therapy, Combination; Female; Humans; Immunotherapy; Kidney Neoplasms; Lomustine; Male; Mice; Mice, Inbred BALB C; Neoplasm Regression, Spontaneous; Neoplasms, Experimental; Progestins; Remission, Spontaneous; Semustine; Vinblastine | 1977 |
Nitrosoureas: a review of experimental antitumor activity.
Topics: Animals; Carmustine; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Leukemia L1210; Lomustine; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Semustine | 1976 |
Chemotherapy: the agents in current use.
Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Dacarbazine; Drug Therapy, Combination; Glioma; Humans; Lomustine; Medulloblastoma; Methotrexate; Nitrogen Mustard Compounds; Procarbazine; Semustine; Teniposide; Vincristine | 1975 |
[Nitrosourea-induced lung diseases].
Topics: Adult; Brain Neoplasms; Carmustine; Child; Drug Therapy, Combination; Female; Humans; Iatrogenic Disease; Lomustine; Lung; Lung Diseases; Nitrosourea Compounds; Pneumonia; Prognosis; Pulmonary Fibrosis; Risk Factors; Semustine | 1992 |
[Chemotherapy of cancer of the large intestine].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colonic Neoplasms; Drug Evaluation; Fluorouracil; Humans; Lomustine; Melphalan; Methotrexate; Rectal Neoplasms; Semustine; Vincristine | 1985 |
Chemotherapy in alimentary tract malignomas.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carmustine; Colonic Neoplasms; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lomustine; Male; Methotrexate; Mitomycin; Mitomycins; Rectal Neoplasms; Semustine; Stomach Neoplasms; Streptozocin; Tegafur; Vincristine | 1981 |
[Cancer chemotherapy with special reference to pharmacokinetics of nitrosoureas].
Topics: Carmustine; Humans; Kinetics; Lomustine; Neoplasms; Nimustine; Nitrosourea Compounds; Semustine; Solubility; Streptozocin | 1982 |
Cytotoxic agents effective in prostate cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Lomustine; Male; Methotrexate; Prostatic Neoplasms; Semustine | 1983 |
Treatment of neuroectodermal brain tumors.
Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Therapy, Combination; Glioma; Humans; Lomustine; Middle Aged; Mitotic Index; Oligodendroglioma; Prospective Studies; Random Allocation; Semustine | 1982 |
[Clinical significance of mustoforan in management of malignant glioma].
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Disease-Free Survival; Female; Glioblastoma; Glioma; Humans; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm, Residual; Nitrosourea Compounds; Oligodendroglioma; Organophosphorus Compounds; Semustine; Survival Analysis; Treatment Outcome | 2007 |
12 trial(s) available for semustine and lomustine
Article | Year |
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Chemotherapy: adjuvant to surgery and radiation therapy.
Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Fluorouracil; Glioma; Humans; Lomustine; Maryland; Plicamycin; Prospective Studies; Semustine; Vincristine | 1975 |
Nitrosourea combinations in lung cancer.
Topics: Adenocarcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Carmustine; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Humans; Lomustine; Lung Neoplasms; Methotrexate; Nitrosourea Compounds; Semustine | 1976 |
Comparison of methyl-CCNU and CCNU in patients with advanced forms of Hodgkin's disease, lymphosarcoma nad reticulum cell sarcoma.
Topics: Clinical Trials as Topic; Female; Hodgkin Disease; Humans; Leukopenia; Lomustine; Lymphoma, Non-Hodgkin; Male; Nitrosourea Compounds; Remission, Spontaneous; Semustine; Thrombocytopenia; Time Factors | 1978 |
Chemotherapy of gynecologic cancer with nitrosoureas: a randomized trial of CCNU and methyl-CCNU in cancers of the cervix, corpus, vagina, and vulva.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Genital Neoplasms, Female; Humans; Lomustine; Nitrosourea Compounds; Sarcoma; Semustine; Uterine Cervical Neoplasms; Uterine Neoplasms; Vaginal Neoplasms; Vulvar Neoplasms | 1978 |
Nitrosoureas in the management of disseminated malignant melanoma.
Topics: Carmustine; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Humans; Lomustine; Melanoma; Nitrosourea Compounds; Semustine | 1976 |
Nitrosoureas as single agents in the treatment of pulmonary cancer.
Topics: Carmustine; Clinical Trials as Topic; Cyclophosphamide; Female; Humans; Lomustine; Lung Neoplasms; Male; Nitrosourea Compounds; Semustine | 1976 |
Nitrosoureas: useful agents for the treatment of advanced gastrointestinal cancer.
Topics: Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Humans; Lomustine; Nitrosourea Compounds; Rectal Neoplasms; Semustine; Stomach Neoplasms; Thioguanine | 1976 |
Southeastern Cancer Study Group trials with nitrosoureas in Hodgkin's disease.
Topics: Administration, Oral; Carmustine; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Hodgkin Disease; Humans; Lomustine; Nitrosourea Compounds; Prednisone; Procarbazine; Semustine; Vinblastine | 1976 |
Chemotherapy for mustard-resistant ovarian adenocarcinoma: a randomized trial for CCNU and methyl-CCNU.
Topics: Adenocarcinoma; Adult; Aged; Drug Administration Schedule; Drug Evaluation; Female; Humans; Lomustine; Middle Aged; Nitrogen Mustard Compounds; Nitrosourea Compounds; Ovarian Neoplasms; Semustine | 1977 |
Adjuvant nitrosourea therapy for glioblastoma.
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Child; Child, Preschool; Drug Evaluation; Female; Glioma; Humans; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Semustine | 1976 |
Treatment of neuroectodermal brain tumors.
Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Therapy, Combination; Glioma; Humans; Lomustine; Middle Aged; Mitotic Index; Oligodendroglioma; Prospective Studies; Random Allocation; Semustine | 1982 |
[Use of nitrosourea compounds in cancer chemotherapy].
Topics: Carmustine; Clinical Trials as Topic; Humans; Lomustine; Neoplasms; Nitrosourea Compounds; Semustine | 1982 |
53 other study(ies) available for semustine and lomustine
Article | Year |
---|---|
Synthesis of analogues of N-(2-chloroethyl)-N'-(trans-4-methylcyclohexyl)-N-nitrosourea for evaluation as anticancer agents.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Isomerism; Leukemia L1210; Mice; Mice, Inbred Strains; Nitrosourea Compounds; Semustine; Structure-Activity Relationship | 1977 |
Inhibition of solid tumors by nitrosoureas. 1. Lewis lung carcinoma.
Topics: Animals; Carcinoma; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosourea Compounds; Structure-Activity Relationship; Time Factors | 1977 |
Antitumor structure-activity relations. Nitrosoureas vs. L-1210 leukemia.
Topics: Animals; Antineoplastic Agents; Leukemia L1210; Mice; Models, Theoretical; Nitrosourea Compounds; Solubility; Structure-Activity Relationship | 1980 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Differential sensitivities of five rat hepatoma cell lines to anticancer drugs.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Cytarabine; Doxorubicin; Drug Resistance; Hydroxyurea; Liver Neoplasms; Lomustine; Neoplasms, Experimental; Rats; Semustine | 1978 |
Examination of four newly synthesized 2-chloroethylnitrosoureas in comparison with BCNU, CCNU, MeCCNU, chlorozotocin and hydroxyethyl-CNU in preterminal rat leukemia L 5222.
Topics: Animals; Carmustine; Drug Evaluation, Preclinical; Female; Leukemia, Experimental; Lomustine; Male; Nitrosourea Compounds; Rats; Semustine; Streptozocin | 1979 |
Adjuvant chemotherapy with nitrosourea compounds following surgery plus radiotherapy in glioblastoma multiforme.
Topics: Brain Neoplasms; Carmustine; Glioblastoma; Humans; Lomustine; Nitrosourea Compounds; Semustine | 1978 |
Mutagenicity of nitrosourea compounds for Salmonella typhimurium.
Topics: Carmustine; Lomustine; Methods; Methylnitrosourea; Mutagens; Nitrosourea Compounds; Salmonella typhimurium; Semustine | 1978 |
Chemotherapy of experimental metastatic brain tumors in female Wistar rats.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carcinoma 256, Walker; Carotid Arteries; Cells, Cultured; Cyclophosphamide; Disease Models, Animal; Female; Lomustine; Methotrexate; Neoplasm Metastasis; Neoplasms, Experimental; Nitrosourea Compounds; Procarbazine; Rats; Semustine | 1979 |
Design and evaluation of combination chemotherapy trials in experimental animal tumor systems.
Topics: Animals; Antineoplastic Agents; Carmustine; Cisplatin; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Therapy, Combination; Evaluation Studies as Topic; Fluorouracil; Lomustine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasms, Experimental; Research Design; Semustine | 1979 |
Evaluation of whole-body hyperthermia as an adjunct to chemotherapy in murine tumors.
Topics: Animals; Antineoplastic Agents; Body Temperature; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Hyperthermia, Induced; Lomustine; Male; Methods; Mice; Neoplasms, Experimental; Semustine; Vincristine | 1979 |
A simple method for producing different growth fractions in vitro for use in anti-cancer drug studies.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Cricetinae; Cricetulus; Drug Evaluation, Preclinical; Lomustine; Nitrosourea Compounds; Semustine | 1979 |
The effect of combination chemotherapy on the reticuloendothelial system in man.
Topics: Aged; Antineoplastic Agents; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lomustine; Macrophages; Male; Middle Aged; Mononuclear Phagocyte System; Neoplasms; Phagocytosis; Semustine; Vincristine | 1978 |
The contemporary role of chemotherapy in the treatment of malignant brain tumor.
Topics: Adrenal Cortex Hormones; Animals; Brain Neoplasms; Carmustine; Dose-Response Relationship, Drug; Drug Evaluation; Glioma; Humans; Inactivation, Metabolic; Lomustine; Neoplasms, Experimental; Prognosis; Radiotherapy Dosage; Semustine | 1978 |
Visual abnormalities following nitrosourea treatment.
Topics: Carmustine; Humans; Lomustine; Nitrosourea Compounds; Retina; Semustine; Vision Disorders; Visual Acuity | 1978 |
Pharmacology of the nitrosoureas: an overview.
Topics: Animals; Carmustine; Dogs; Half-Life; Haplorhini; Humans; Lomustine; Mice; Microsomes, Liver; Nitrosourea Compounds; Semustine | 1976 |
Chemotherapy of an experimental glioma with nitrosoureas.
Topics: Animals; Brain Neoplasms; Drug Administration Schedule; Ependymoma; Female; Glioma; Injections; Injections, Intraperitoneal; Lomustine; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Semustine; Transplantation, Isogeneic | 1977 |
Chemotherapy of experimental meningeal carcinomatosis.
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cyclophosphamide; Cytarabine; Female; Injections, Intraventricular; Lomustine; Meninges; Methotrexate; Rats; Semustine | 1977 |
Gastrointestinal cancer. Treatment with fluorouracil-nitrosourea combinations.
Topics: Carmustine; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Lomustine; Male; Methods; Nitrosourea Compounds; Pancreatic Neoplasms; Rectal Neoplasms; Remission, Spontaneous; Semustine; Stomach Neoplasms | 1976 |
The nitrosoureas: an outline of clinical schedules and toxic effects.
Topics: Administration, Oral; Bone Marrow; Capsules; Carmustine; Humans; Injections, Intravenous; Lomustine; Nausea; Nitrosourea Compounds; Semustine | 1976 |
Nitrosourea chemotherapy for primary malignant gliomas.
Topics: Brain Neoplasms; Carmustine; Drug Therapy, Combination; Fluorouracil; Glioma; Humans; Lomustine; Neoplasm Recurrence, Local; Nitrosourea Compounds; Procarbazine; Semustine; Vincristine | 1976 |
Nitrosourea pharmacodynamics in relation to the central nervous system.
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Glioma; Humans; Lomustine; Mice; Molecular Weight; Neoplasms, Experimental; Nitrosourea Compounds; Semustine; Solubility | 1976 |
Therapy for gastrointestinal cancer with the nitrosoureas alone and in drug combination.
Topics: Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Humans; Lomustine; Nitrosourea Compounds; Semustine; Vincristine | 1976 |
Clinical studies with nitrosoureas in various solid tumors.
Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Squamous Cell; Carmustine; Female; Genital Neoplasms, Female; Head and Neck Neoplasms; Humans; Kidney Neoplasms; Lomustine; Male; Neoplasms; Nitrosourea Compounds; Sarcoma; Semustine; Testicular Neoplasms | 1976 |
Editorial: Large-bowel cancer-The current status of treatment.
Topics: Adjuvants, Immunologic; BCG Vaccine; Carmustine; Colonic Neoplasms; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Immunotherapy; Lomustine; Mitomycins; Neoplasm Metastasis; Neoplasm Recurrence, Local; Rectal Neoplasms; Semustine; United States | 1976 |
A comparison of the lethal effects of three nitrosourea derivatives on cultured human lymphoma cells.
Topics: Amphotericin B; Carmustine; Cell Line; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Lomustine; Lymphoma; Neoplasms, Experimental; Nitrosourea Compounds; Semustine; Time Factors; Vitamin A | 1976 |
Base sequence specificity of three 2-chloroethylnitrosoureas.
Topics: Alkylation; Base Sequence; Carmustine; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; DNA; Guanine; Lomustine; Nitrosourea Compounds; Semustine; Structure-Activity Relationship | 1990 |
Glutathione and related enzymes in rat brain tumor cell resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea and nitrogen mustard.
Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Carmustine; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Clone Cells; Dinitrochlorobenzene; Drug Resistance; gamma-Glutamyltransferase; Glioma; Glutathione; Glutathione Transferase; Lomustine; Mechlorethamine; Methionine Sulfoximine; Rats; Semustine | 1987 |
Effect of nitrosoureas on calmodulin activity in vitro and in mouse intestine in vivo.
Topics: Animals; Calcium; Calmodulin; Carmustine; Cattle; Cyanates; Cyclic AMP; Intestinal Mucosa; Intestines; Lomustine; Male; Mice; Nitrosourea Compounds; Phosphoric Diester Hydrolases; Semustine; Streptozocin | 1985 |
Effect of Fluosol-DA/O2 on tumor-cell and bone-marrow cytotoxicity of nitrosoureas in mice bearing FSA-II fibrosarcoma.
Topics: Animals; Bone Marrow; Carbon Dioxide; Carmustine; Cell Survival; Drug Combinations; Fibrosarcoma; Fluorocarbons; Hydroxyethyl Starch Derivatives; Lomustine; Male; Mice; Mice, Inbred C3H; Nitrosourea Compounds; Oxygen; Semustine | 1986 |
Emergence of nitrosourea resistant sublines of Lewis lung tumour following MeCCNU treatment in vivo.
Topics: Animals; Carmustine; Cell Line; Cell Survival; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Resistance; Lomustine; Lung Neoplasms; Melphalan; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Nitrosourea Compounds; Semustine; Time Factors | 1986 |
Therapeutic evaluation of five nitrosoureas in a human melanoma xenograft system.
Topics: Animals; Bone Marrow; Brain Neoplasms; Carmustine; Dose-Response Relationship, Drug; Female; Humans; Lomustine; Male; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Nitrosourea Compounds; Semustine; Streptozocin; Transplantation Immunology; Transplantation, Heterologous | 1983 |
Nitroimidazoles as modifiers of nitrosourea pharmacokinetics.
Topics: Animals; Antineoplastic Agents; Carmustine; Lomustine; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Nitrosourea Compounds; Radiation-Sensitizing Agents; Semustine; Streptozocin; Time Factors | 1984 |
Adjuvant therapy for carcinoma of the colon and rectum.
Topics: Antineoplastic Agents; Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; Lomustine; Male; Prognosis; Radiotherapy Dosage; Rectal Neoplasms; Semustine | 1984 |
[Antitumor activity of a new nitrosourea, MCNU, on a cellular morphological basis evaluated by a new in vitro antitumor sensitivity assay].
Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Humans; In Vitro Techniques; Leukemia L1210; Lomustine; Nimustine; Nitrosourea Compounds; Semustine; Tumor Stem Cell Assay | 1984 |
cis-4-[[[(2-Chloroethyl)nitrosoamino]carbonyl]methylamino] cyclohexanecarboxylic acid, a nitrosourea with latent activity against an experimental solid tumor.
Topics: Animals; Antineoplastic Agents; Drug Evaluation, Preclinical; Half-Life; Indicators and Reagents; Lomustine; Lung Neoplasms; Mice; Semustine; Structure-Activity Relationship | 1984 |
Stereoselective monooxygenation of carcinostatic 1-(2-chloroethyl)-3-(cyclohexyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea by purified cytochrome P-450 isozymes.
Topics: Animals; Cytochrome P-450 Enzyme System; Hydroxylation; In Vitro Techniques; Isoenzymes; Lomustine; Microsomes, Liver; Nitrosourea Compounds; Rats; Semustine; Stereoisomerism | 1984 |
[Chemotherapy of stomach cancer].
Topics: Adenocarcinoma; Antineoplastic Agents; Carmustine; Cisplatin; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Gastrectomy; Humans; Lomustine; Mitomycin; Mitomycins; Neoplasm Recurrence, Local; Prognosis; Semustine; Stomach Neoplasms | 1982 |
Quantitative dose-response relations for the cytotoxic activity of chloroethylnitrosoureas in cell culture.
Topics: Animals; Biotransformation; Brain Neoplasms; Carmustine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Lomustine; Mustard Compounds; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Semustine; Structure-Activity Relationship; Time Factors | 1982 |
Determination of two nitrosourea antitumor agents by chemical ionization gas chromatography--mass spectrometry.
Topics: Animals; Dogs; Gas Chromatography-Mass Spectrometry; Humans; Lomustine; Nitrosourea Compounds; Semustine; Time Factors | 1982 |
[Combination chemotherapy of transplanted rat leukemia L 5222 with 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and cyclophosphamide (CPA) as well as with methyl-CCNU and CPA (author's transl)].
Topics: Animals; Cyclophosphamide; Drug Therapy, Combination; Leukemia, Experimental; Lomustine; Male; Neoplasm Transplantation; Nitrosourea Compounds; Rats; Semustine; Transplantation, Homologous | 1981 |
Evaluation of vincristine, CCNU and methyl-CCNU at high level doses in an experimental murine renal adenocarcinoma model.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Kidney Neoplasms; Lomustine; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Semustine; Transplantation, Homologous; Vincristine | 1981 |
Mechanism of action of (2-haloethyl)nitrosoureas on DNA. Isolation and reactions of postulated 2-(alkylimino)-3-nitrosooxazolidine intermediates in the decomposition of 1,3-bis(2-chloroethyl)-, 1-(2-chloroethyl)-3-cyclohexyl-, and 1-(2-chloroethyl)-3-(4'-
Topics: Alkylation; Antineoplastic Agents; Carmustine; Chemical Phenomena; Chemistry; DNA; Lomustine; Nitrosourea Compounds; Semustine | 1981 |
Analysis for nitrosourea antitumor agents by gas chromatography--mass spectrometry.
Topics: Animals; Antineoplastic Agents; Carmustine; Dogs; Gas Chromatography-Mass Spectrometry; Lomustine; Nitrosourea Compounds; Semustine | 1981 |
Nephrotoxicity of nitrosoureas.
Topics: Adolescent; Adult; Aged; Biopsy; Blood Urea Nitrogen; Brain Neoplasms; Carmustine; Child; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Kidney; Kidney Diseases; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Retrospective Studies; Semustine | 1981 |
Chronic toxicity and carcinogenicity of cytostatic N-nitroso-(2-chloroethyl) ureas after repeated intravenous application to rats.
Topics: Animals; Antineoplastic Agents; Carcinogens; Carmustine; Lomustine; Lung Neoplasms; Male; Neoplasms, Experimental; Nervous System Neoplasms; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Semustine; Stomach Neoplasms | 1980 |
Lipophilic drugs and lipoproteins: partitioning effects on chloroethylnitrosourea reaction rates in serum.
Topics: Carmustine; Humans; In Vitro Techniques; Kinetics; Lipids; Lipoproteins; Lomustine; Models, Biological; Nitrosourea Compounds; Semustine; Solubility | 1980 |
Distribution of Bratton-Marshall-positive material in mice following intravenous injections of nitrosoureas.
Topics: Animals; Biotransformation; Carmustine; Colorimetry; Injections, Intravenous; Lomustine; Mice; Nitrosourea Compounds; Semustine; Tissue Distribution | 1980 |
[Use of BCG as an immunoadjuvant in combination with antitumor agents in virus-induced leukemia].
Topics: Animals; Antineoplastic Agents; BCG Vaccine; Carmustine; Drug Synergism; Drug Therapy, Combination; Hybridization, Genetic; Leukemia, Experimental; Lomustine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Moloney murine leukemia virus; Neoplasm Transplantation; Semustine; Time Factors | 1980 |
Long term response to chemotherapy in patients with visceral metastatic melanoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Female; Humans; Interferon-alpha; Lomustine; Male; Melanoma; Middle Aged; Remission Induction; Semustine; Survival Rate | 1994 |
Comparison of DNA lesions produced by tumor-inhibitory 1,2-bis(sulfonyl)hydrazines and chloroethylnitrosoureas.
Topics: Antineoplastic Agents, Alkylating; Bacteriophage T7; Carmustine; Cross-Linking Reagents; DNA; DNA Damage; DNA, Viral; Isocyanates; Lomustine; Semustine | 2000 |
Combined chemoradiation for the management of nasal natural killer (NK)/T-cell lymphoma: elucidating the significance of systemic chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Lomustine; Lymphoma, Extranodal NK-T-Cell; Male; Middle Aged; Nose Neoplasms; Retrospective Studies; Semustine; Survival Rate | 2008 |
Molecular modeling and spectroscopic studies of semustine binding with DNA and its comparison with lomustine-DNA adduct formation.
Topics: Algorithms; Antineoplastic Agents, Alkylating; Circular Dichroism; DNA; DNA Adducts; Lomustine; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Semustine; Spectroscopy, Fourier Transform Infrared | 2015 |