Page last updated: 2024-08-16

semustine and lomustine

semustine has been researched along with lomustine in 75 studies

Research

Studies (75)

TimeframeStudies, this research(%)All Research%
pre-199067 (89.33)18.7374
1990's3 (4.00)18.2507
2000's4 (5.33)29.6817
2010's1 (1.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Clayton, SD; Frye, JL; Johnston, TP; Krauth, CA; McCaleb, GS; Montgomery, JA1
Johnston, TP; Laster, WR; Mayo, JG; McCaleb, GS; Montgomery, JA1
Hansch, C; Jow, PY; Leo, A; Montgomery, JA; Schmidt, C1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barranco, SC; Gee, EL; Haenelt, BR1
Walker, MD2
Eisenbrand, G; Fiebig, HH; Zeller, WJ1
Bono, VH1
Livingston, RB1
Bonadonna, G; Brambilla, C; Monfardini, S; Morello, G; Solero, CL; Vaghi, A; Valagussa, P1
Hrushesky, WJ; Murphy, GP1
Burningham, RA; Carey, R; Cornell, CJ; Glidewell, O; Holland, JF; Jacquillat, C; Maurice, P; Nissen, NI; Pas, AT; Silver, RT1
Auletta, AE; Martz, AG; Parmar, AS1
Blessing, JA; Boronow, RC; Creasman, WT; Omura, GA; Shingleton, HM1
Hasegawa, H; Posner, JB; Shapiro, WR1
Corbett, TH; Griswold, DP; Schabel, FM; Venditti, JM; Wolpert, MK1
Laster, WR; Rose, WC; Schabel, FM; Veras, GH1
Barranco, SC; Bolton, WE; Novak, JK1
Athlin, L; Berghem, L; Domellöf, L1
Bono, VH; Louie, AC; Muggia, FM; Turrisi, AT1
Schabel, FM1
Ahmann, DL1
Wolf, J1
Douglass, HO; Lavin, PT; Moertel, CG1
Bartolucci, A; Dorfman, RF; Durant, JR; Gams, RA; Velez-Garcia, E1
Levin, VA; Wilson, CB2
Oliverio, VT1
Day, A; Liberman, L; Ng, R; Tator, CH1
Posner, JB; Shapiro, WR; Ushio, Y1
Blessing, J; Boronow, R; DiSaia, P; Hreshchyshyn, M; Omura, G; Park, R1
Moertel, CG1
Wasserman, TH1
Hilton, J; Walker, MD1
Hahn, RG; Moertel, CG; Reitemeier, RJ; Schutt, AJ1
Balis, E; Brisman, R; Chang, C; Duffy, P; Housepian, EM1
Slavik, M1
Carter, SK1
Drewinko, B; Gottlieb, JA; Loo, TL1
Camus, P; Coudert, B; Foucher, P; Jeannin, L; Lombard, JN; Massin, F; Reybet-Degat, O1
Anderson, SP; Briscoe, WT; May, HE1
Bodell, WJ; Doane-Setzer, P; Evans, CG; Smith, MT; Tokuda, K1
Giles, RC; Harrison, SD; Mann, DM1
Holden, SA; Rose, CM; Teicher, BA1
Ozhiganov, EL; Platinskiĭ, LV; Sokolova, VD1
Adams, K; Peacock, JH; Stephens, TC1
Heim, ME; Queisser, W1
Wakui, A1
Glatte, P; Osieka, R; Pannenbäcker, R; Schmidt, CG1
Lee, FY; Workman, P1
Schmidt, JD1
Higgins, GA1
Oguro, M; Takenaga, K; Yanagawa, T1
Johnston, TP; McCaleb, GS; Montgomery, JA; Rose, WC1
Levin, W; Potter, DW; Reed, DJ; Ryan, DE; Thomas, PE1
Shapiro, WR1
Robak, T1
Gropp, C; Havemann, K1
Deen, DF; Weinkam, RJ1
Cheung, LK; Smith, RG1
Berger, M; Zeller, WJ1
Kantor, P; Murphy, GP; Williams, PD1
Chauhan, SM; Lown, JW1
Blackstock, SC; Cheung, LK; Loo, TL; Smith, RG1
Baldwin, DS; Feiner, HD; Gallo, GR; Lieberman, A; Schacht, RG1
Eisenbrand, G; Habs, M1
Finn, A; Kane, JP; Levin, VA; Weinkam, RJ1
Finkel, JM; Hill, DL; Kari, P; McConnell, WR1
Cenci, E; Perito, S; Sbaraglia, G; Vecchiarelli, A1
Coates, AS; Segelov, E1
Penketh, PG; Sartorelli, AC; Shyam, K1
Guo, Y; Hong, X; Li, J; Li, X; Lu, JJ; Ma, X; Wang, B1
Kobiakov, GL1
Agarwal, S; Chadha, D; Mehrotra, R1

Reviews

11 review(s) available for semustine and lomustine

ArticleYear
Review of mechanism of action studies of the nitrosoureas.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Alkylating Agents; Animals; Bone Marrow; Bone Marrow Cells; Carmustine; Cell Division; Cell Survival; DNA; DNA, Neoplasm; Ethyl Chloride; Lomustine; Mice; NAD+ Nucleosidase; Neoplasms, Experimental; Nitrosourea Compounds; Protein Biosynthesis; RNA; Semustine; Streptozocin

1976
Current status of the therapy of advanced renal carcinoma.
    Journal of surgical oncology, 1977, Volume: 9, Issue:3

    Topics: Adenocarcinoma; Androgens; Animals; Antineoplastic Agents; Drug Therapy, Combination; Female; Humans; Immunotherapy; Kidney Neoplasms; Lomustine; Male; Mice; Mice, Inbred BALB C; Neoplasm Regression, Spontaneous; Neoplasms, Experimental; Progestins; Remission, Spontaneous; Semustine; Vinblastine

1977
Nitrosoureas: a review of experimental antitumor activity.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Animals; Carmustine; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Leukemia L1210; Lomustine; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Semustine

1976
Chemotherapy: the agents in current use.
    Seminars in oncology, 1975, Volume: 2, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Dacarbazine; Drug Therapy, Combination; Glioma; Humans; Lomustine; Medulloblastoma; Methotrexate; Nitrogen Mustard Compounds; Procarbazine; Semustine; Teniposide; Vincristine

1975
[Nitrosourea-induced lung diseases].
    Revue des maladies respiratoires, 1992, Volume: 9, Issue:6

    Topics: Adult; Brain Neoplasms; Carmustine; Child; Drug Therapy, Combination; Female; Humans; Iatrogenic Disease; Lomustine; Lung; Lung Diseases; Nitrosourea Compounds; Pneumonia; Prognosis; Pulmonary Fibrosis; Risk Factors; Semustine

1992
[Chemotherapy of cancer of the large intestine].
    Sovetskaia meditsina, 1985, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colonic Neoplasms; Drug Evaluation; Fluorouracil; Humans; Lomustine; Melphalan; Methotrexate; Rectal Neoplasms; Semustine; Vincristine

1985
Chemotherapy in alimentary tract malignomas.
    Hepato-gastroenterology, 1981, Volume: 28, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carmustine; Colonic Neoplasms; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lomustine; Male; Methotrexate; Mitomycin; Mitomycins; Rectal Neoplasms; Semustine; Stomach Neoplasms; Streptozocin; Tegafur; Vincristine

1981
[Cancer chemotherapy with special reference to pharmacokinetics of nitrosoureas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:8

    Topics: Carmustine; Humans; Kinetics; Lomustine; Neoplasms; Nimustine; Nitrosourea Compounds; Semustine; Solubility; Streptozocin

1982
Cytotoxic agents effective in prostate cancer.
    Seminars in urology, 1983, Volume: 1, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Lomustine; Male; Methotrexate; Prostatic Neoplasms; Semustine

1983
Treatment of neuroectodermal brain tumors.
    Annals of neurology, 1982, Volume: 12, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Therapy, Combination; Glioma; Humans; Lomustine; Middle Aged; Mitotic Index; Oligodendroglioma; Prospective Studies; Random Allocation; Semustine

1982
[Clinical significance of mustoforan in management of malignant glioma].
    Voprosy onkologii, 2007, Volume: 53, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Disease-Free Survival; Female; Glioblastoma; Glioma; Humans; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm, Residual; Nitrosourea Compounds; Oligodendroglioma; Organophosphorus Compounds; Semustine; Survival Analysis; Treatment Outcome

2007

Trials

12 trial(s) available for semustine and lomustine

ArticleYear
Chemotherapy: adjuvant to surgery and radiation therapy.
    Seminars in oncology, 1975, Volume: 2, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Fluorouracil; Glioma; Humans; Lomustine; Maryland; Plicamycin; Prospective Studies; Semustine; Vincristine

1975
Nitrosourea combinations in lung cancer.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Adenocarcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Carmustine; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Humans; Lomustine; Lung Neoplasms; Methotrexate; Nitrosourea Compounds; Semustine

1976
Comparison of methyl-CCNU and CCNU in patients with advanced forms of Hodgkin's disease, lymphosarcoma nad reticulum cell sarcoma.
    Cancer, 1978, Volume: 41, Issue:5

    Topics: Clinical Trials as Topic; Female; Hodgkin Disease; Humans; Leukopenia; Lomustine; Lymphoma, Non-Hodgkin; Male; Nitrosourea Compounds; Remission, Spontaneous; Semustine; Thrombocytopenia; Time Factors

1978
Chemotherapy of gynecologic cancer with nitrosoureas: a randomized trial of CCNU and methyl-CCNU in cancers of the cervix, corpus, vagina, and vulva.
    Cancer treatment reports, 1978, Volume: 62, Issue:5

    Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Clinical Trials as Topic; Female; Genital Neoplasms, Female; Humans; Lomustine; Nitrosourea Compounds; Sarcoma; Semustine; Uterine Cervical Neoplasms; Uterine Neoplasms; Vaginal Neoplasms; Vulvar Neoplasms

1978
Nitrosoureas in the management of disseminated malignant melanoma.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Carmustine; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Humans; Lomustine; Melanoma; Nitrosourea Compounds; Semustine

1976
Nitrosoureas as single agents in the treatment of pulmonary cancer.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Carmustine; Clinical Trials as Topic; Cyclophosphamide; Female; Humans; Lomustine; Lung Neoplasms; Male; Nitrosourea Compounds; Semustine

1976
Nitrosoureas: useful agents for the treatment of advanced gastrointestinal cancer.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Humans; Lomustine; Nitrosourea Compounds; Rectal Neoplasms; Semustine; Stomach Neoplasms; Thioguanine

1976
Southeastern Cancer Study Group trials with nitrosoureas in Hodgkin's disease.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Administration, Oral; Carmustine; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Hodgkin Disease; Humans; Lomustine; Nitrosourea Compounds; Prednisone; Procarbazine; Semustine; Vinblastine

1976
Chemotherapy for mustard-resistant ovarian adenocarcinoma: a randomized trial for CCNU and methyl-CCNU.
    Cancer treatment reports, 1977, Volume: 61, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Drug Administration Schedule; Drug Evaluation; Female; Humans; Lomustine; Middle Aged; Nitrogen Mustard Compounds; Nitrosourea Compounds; Ovarian Neoplasms; Semustine

1977
Adjuvant nitrosourea therapy for glioblastoma.
    Archives of neurology, 1976, Volume: 33, Issue:11

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Child; Child, Preschool; Drug Evaluation; Female; Glioma; Humans; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Semustine

1976
Treatment of neuroectodermal brain tumors.
    Annals of neurology, 1982, Volume: 12, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Therapy, Combination; Glioma; Humans; Lomustine; Middle Aged; Mitotic Index; Oligodendroglioma; Prospective Studies; Random Allocation; Semustine

1982
[Use of nitrosourea compounds in cancer chemotherapy].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1982, Sep-27, Volume: 37, Issue:36

    Topics: Carmustine; Clinical Trials as Topic; Humans; Lomustine; Neoplasms; Nitrosourea Compounds; Semustine

1982

Other Studies

53 other study(ies) available for semustine and lomustine

ArticleYear
Synthesis of analogues of N-(2-chloroethyl)-N'-(trans-4-methylcyclohexyl)-N-nitrosourea for evaluation as anticancer agents.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:2

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Isomerism; Leukemia L1210; Mice; Mice, Inbred Strains; Nitrosourea Compounds; Semustine; Structure-Activity Relationship

1977
Inhibition of solid tumors by nitrosoureas. 1. Lewis lung carcinoma.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:2

    Topics: Animals; Carcinoma; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosourea Compounds; Structure-Activity Relationship; Time Factors

1977
Antitumor structure-activity relations. Nitrosoureas vs. L-1210 leukemia.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:10

    Topics: Animals; Antineoplastic Agents; Leukemia L1210; Mice; Models, Theoretical; Nitrosourea Compounds; Solubility; Structure-Activity Relationship

1980
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Differential sensitivities of five rat hepatoma cell lines to anticancer drugs.
    Cancer research, 1978, Volume: 38, Issue:3

    Topics: Animals; Antineoplastic Agents; Bleomycin; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Cytarabine; Doxorubicin; Drug Resistance; Hydroxyurea; Liver Neoplasms; Lomustine; Neoplasms, Experimental; Rats; Semustine

1978
Examination of four newly synthesized 2-chloroethylnitrosoureas in comparison with BCNU, CCNU, MeCCNU, chlorozotocin and hydroxyethyl-CNU in preterminal rat leukemia L 5222.
    Journal of cancer research and clinical oncology, 1979, Volume: 95, Issue:1

    Topics: Animals; Carmustine; Drug Evaluation, Preclinical; Female; Leukemia, Experimental; Lomustine; Male; Nitrosourea Compounds; Rats; Semustine; Streptozocin

1979
Adjuvant chemotherapy with nitrosourea compounds following surgery plus radiotherapy in glioblastoma multiforme.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1978, Volume: 68

    Topics: Brain Neoplasms; Carmustine; Glioblastoma; Humans; Lomustine; Nitrosourea Compounds; Semustine

1978
Mutagenicity of nitrosourea compounds for Salmonella typhimurium.
    Journal of the National Cancer Institute, 1978, Volume: 60, Issue:6

    Topics: Carmustine; Lomustine; Methods; Methylnitrosourea; Mutagens; Nitrosourea Compounds; Salmonella typhimurium; Semustine

1978
Chemotherapy of experimental metastatic brain tumors in female Wistar rats.
    Cancer research, 1979, Volume: 39, Issue:7 Pt 1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carcinoma 256, Walker; Carotid Arteries; Cells, Cultured; Cyclophosphamide; Disease Models, Animal; Female; Lomustine; Methotrexate; Neoplasm Metastasis; Neoplasms, Experimental; Nitrosourea Compounds; Procarbazine; Rats; Semustine

1979
Design and evaluation of combination chemotherapy trials in experimental animal tumor systems.
    Cancer treatment reports, 1979, Volume: 63, Issue:5

    Topics: Animals; Antineoplastic Agents; Carmustine; Cisplatin; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Therapy, Combination; Evaluation Studies as Topic; Fluorouracil; Lomustine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasms, Experimental; Research Design; Semustine

1979
Evaluation of whole-body hyperthermia as an adjunct to chemotherapy in murine tumors.
    Cancer treatment reports, 1979, Volume: 63, Issue:8

    Topics: Animals; Antineoplastic Agents; Body Temperature; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Hyperthermia, Induced; Lomustine; Male; Methods; Mice; Neoplasms, Experimental; Semustine; Vincristine

1979
A simple method for producing different growth fractions in vitro for use in anti-cancer drug studies.
    Cell and tissue kinetics, 1979, Volume: 12, Issue:1

    Topics: Animals; Cell Division; Cell Line; Cell Survival; Cricetinae; Cricetulus; Drug Evaluation, Preclinical; Lomustine; Nitrosourea Compounds; Semustine

1979
The effect of combination chemotherapy on the reticuloendothelial system in man.
    Cancer letters, 1978, Volume: 5, Issue:1

    Topics: Aged; Antineoplastic Agents; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lomustine; Macrophages; Male; Middle Aged; Mononuclear Phagocyte System; Neoplasms; Phagocytosis; Semustine; Vincristine

1978
The contemporary role of chemotherapy in the treatment of malignant brain tumor.
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Adrenal Cortex Hormones; Animals; Brain Neoplasms; Carmustine; Dose-Response Relationship, Drug; Drug Evaluation; Glioma; Humans; Inactivation, Metabolic; Lomustine; Neoplasms, Experimental; Prognosis; Radiotherapy Dosage; Semustine

1978
Visual abnormalities following nitrosourea treatment.
    Medical and pediatric oncology, 1978, Volume: 5, Issue:1

    Topics: Carmustine; Humans; Lomustine; Nitrosourea Compounds; Retina; Semustine; Vision Disorders; Visual Acuity

1978
Pharmacology of the nitrosoureas: an overview.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Animals; Carmustine; Dogs; Half-Life; Haplorhini; Humans; Lomustine; Mice; Microsomes, Liver; Nitrosourea Compounds; Semustine

1976
Chemotherapy of an experimental glioma with nitrosoureas.
    Cancer research, 1977, Volume: 37, Issue:2

    Topics: Animals; Brain Neoplasms; Drug Administration Schedule; Ependymoma; Female; Glioma; Injections; Injections, Intraperitoneal; Lomustine; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Semustine; Transplantation, Isogeneic

1977
Chemotherapy of experimental meningeal carcinomatosis.
    Cancer research, 1977, Volume: 37, Issue:4

    Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cyclophosphamide; Cytarabine; Female; Injections, Intraventricular; Lomustine; Meninges; Methotrexate; Rats; Semustine

1977
Gastrointestinal cancer. Treatment with fluorouracil-nitrosourea combinations.
    JAMA, 1976, May-10, Volume: 235, Issue:19

    Topics: Carmustine; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Lomustine; Male; Methods; Nitrosourea Compounds; Pancreatic Neoplasms; Rectal Neoplasms; Remission, Spontaneous; Semustine; Stomach Neoplasms

1976
The nitrosoureas: an outline of clinical schedules and toxic effects.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Administration, Oral; Bone Marrow; Capsules; Carmustine; Humans; Injections, Intravenous; Lomustine; Nausea; Nitrosourea Compounds; Semustine

1976
Nitrosourea chemotherapy for primary malignant gliomas.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Brain Neoplasms; Carmustine; Drug Therapy, Combination; Fluorouracil; Glioma; Humans; Lomustine; Neoplasm Recurrence, Local; Nitrosourea Compounds; Procarbazine; Semustine; Vincristine

1976
Nitrosourea pharmacodynamics in relation to the central nervous system.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Glioma; Humans; Lomustine; Mice; Molecular Weight; Neoplasms, Experimental; Nitrosourea Compounds; Semustine; Solubility

1976
Therapy for gastrointestinal cancer with the nitrosoureas alone and in drug combination.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Humans; Lomustine; Nitrosourea Compounds; Semustine; Vincristine

1976
Clinical studies with nitrosoureas in various solid tumors.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Squamous Cell; Carmustine; Female; Genital Neoplasms, Female; Head and Neck Neoplasms; Humans; Kidney Neoplasms; Lomustine; Male; Neoplasms; Nitrosourea Compounds; Sarcoma; Semustine; Testicular Neoplasms

1976
Editorial: Large-bowel cancer-The current status of treatment.
    Journal of the National Cancer Institute, 1976, Volume: 56, Issue:1

    Topics: Adjuvants, Immunologic; BCG Vaccine; Carmustine; Colonic Neoplasms; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Immunotherapy; Lomustine; Mitomycins; Neoplasm Metastasis; Neoplasm Recurrence, Local; Rectal Neoplasms; Semustine; United States

1976
A comparison of the lethal effects of three nitrosourea derivatives on cultured human lymphoma cells.
    Cancer research, 1976, Volume: 36, Issue:2 Pt 1

    Topics: Amphotericin B; Carmustine; Cell Line; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Lomustine; Lymphoma; Neoplasms, Experimental; Nitrosourea Compounds; Semustine; Time Factors; Vitamin A

1976
Base sequence specificity of three 2-chloroethylnitrosoureas.
    Biochemical pharmacology, 1990, Sep-15, Volume: 40, Issue:6

    Topics: Alkylation; Base Sequence; Carmustine; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; DNA; Guanine; Lomustine; Nitrosourea Compounds; Semustine; Structure-Activity Relationship

1990
Glutathione and related enzymes in rat brain tumor cell resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea and nitrogen mustard.
    Cancer research, 1987, May-15, Volume: 47, Issue:10

    Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Carmustine; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Clone Cells; Dinitrochlorobenzene; Drug Resistance; gamma-Glutamyltransferase; Glioma; Glutathione; Glutathione Transferase; Lomustine; Mechlorethamine; Methionine Sulfoximine; Rats; Semustine

1987
Effect of nitrosoureas on calmodulin activity in vitro and in mouse intestine in vivo.
    Cancer chemotherapy and pharmacology, 1985, Volume: 14, Issue:2

    Topics: Animals; Calcium; Calmodulin; Carmustine; Cattle; Cyanates; Cyclic AMP; Intestinal Mucosa; Intestines; Lomustine; Male; Mice; Nitrosourea Compounds; Phosphoric Diester Hydrolases; Semustine; Streptozocin

1985
Effect of Fluosol-DA/O2 on tumor-cell and bone-marrow cytotoxicity of nitrosoureas in mice bearing FSA-II fibrosarcoma.
    International journal of cancer, 1986, Aug-15, Volume: 38, Issue:2

    Topics: Animals; Bone Marrow; Carbon Dioxide; Carmustine; Cell Survival; Drug Combinations; Fibrosarcoma; Fluorocarbons; Hydroxyethyl Starch Derivatives; Lomustine; Male; Mice; Mice, Inbred C3H; Nitrosourea Compounds; Oxygen; Semustine

1986
Emergence of nitrosourea resistant sublines of Lewis lung tumour following MeCCNU treatment in vivo.
    British journal of cancer, 1986, Volume: 53, Issue:2

    Topics: Animals; Carmustine; Cell Line; Cell Survival; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Resistance; Lomustine; Lung Neoplasms; Melphalan; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Nitrosourea Compounds; Semustine; Time Factors

1986
Therapeutic evaluation of five nitrosoureas in a human melanoma xenograft system.
    Cancer chemotherapy and pharmacology, 1983, Volume: 11, Issue:3

    Topics: Animals; Bone Marrow; Brain Neoplasms; Carmustine; Dose-Response Relationship, Drug; Female; Humans; Lomustine; Male; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Nitrosourea Compounds; Semustine; Streptozocin; Transplantation Immunology; Transplantation, Heterologous

1983
Nitroimidazoles as modifiers of nitrosourea pharmacokinetics.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9

    Topics: Animals; Antineoplastic Agents; Carmustine; Lomustine; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Nitrosourea Compounds; Radiation-Sensitizing Agents; Semustine; Streptozocin; Time Factors

1984
Adjuvant therapy for carcinoma of the colon and rectum.
    International advances in surgical oncology, 1984, Volume: 7

    Topics: Antineoplastic Agents; Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; Lomustine; Male; Prognosis; Radiotherapy Dosage; Rectal Neoplasms; Semustine

1984
[Antitumor activity of a new nitrosourea, MCNU, on a cellular morphological basis evaluated by a new in vitro antitumor sensitivity assay].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:12 Pt 1

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Humans; In Vitro Techniques; Leukemia L1210; Lomustine; Nimustine; Nitrosourea Compounds; Semustine; Tumor Stem Cell Assay

1984
cis-4-[[[(2-Chloroethyl)nitrosoamino]carbonyl]methylamino] cyclohexanecarboxylic acid, a nitrosourea with latent activity against an experimental solid tumor.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:1

    Topics: Animals; Antineoplastic Agents; Drug Evaluation, Preclinical; Half-Life; Indicators and Reagents; Lomustine; Lung Neoplasms; Mice; Semustine; Structure-Activity Relationship

1984
Stereoselective monooxygenation of carcinostatic 1-(2-chloroethyl)-3-(cyclohexyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea by purified cytochrome P-450 isozymes.
    Biochemical pharmacology, 1984, Feb-15, Volume: 33, Issue:4

    Topics: Animals; Cytochrome P-450 Enzyme System; Hydroxylation; In Vitro Techniques; Isoenzymes; Lomustine; Microsomes, Liver; Nitrosourea Compounds; Rats; Semustine; Stereoisomerism

1984
[Chemotherapy of stomach cancer].
    Zeitschrift fur Gastroenterologie, 1982, Volume: 20, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Agents; Carmustine; Cisplatin; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Gastrectomy; Humans; Lomustine; Mitomycin; Mitomycins; Neoplasm Recurrence, Local; Prognosis; Semustine; Stomach Neoplasms

1982
Quantitative dose-response relations for the cytotoxic activity of chloroethylnitrosoureas in cell culture.
    Cancer research, 1982, Volume: 42, Issue:3

    Topics: Animals; Biotransformation; Brain Neoplasms; Carmustine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Lomustine; Mustard Compounds; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Semustine; Structure-Activity Relationship; Time Factors

1982
Determination of two nitrosourea antitumor agents by chemical ionization gas chromatography--mass spectrometry.
    Journal of chromatography, 1982, May-14, Volume: 229, Issue:2

    Topics: Animals; Dogs; Gas Chromatography-Mass Spectrometry; Humans; Lomustine; Nitrosourea Compounds; Semustine; Time Factors

1982
[Combination chemotherapy of transplanted rat leukemia L 5222 with 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and cyclophosphamide (CPA) as well as with methyl-CCNU and CPA (author's transl)].
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:2

    Topics: Animals; Cyclophosphamide; Drug Therapy, Combination; Leukemia, Experimental; Lomustine; Male; Neoplasm Transplantation; Nitrosourea Compounds; Rats; Semustine; Transplantation, Homologous

1981
Evaluation of vincristine, CCNU and methyl-CCNU at high level doses in an experimental murine renal adenocarcinoma model.
    Research communications in chemical pathology and pharmacology, 1981, Volume: 31, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Kidney Neoplasms; Lomustine; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Semustine; Transplantation, Homologous; Vincristine

1981
Mechanism of action of (2-haloethyl)nitrosoureas on DNA. Isolation and reactions of postulated 2-(alkylimino)-3-nitrosooxazolidine intermediates in the decomposition of 1,3-bis(2-chloroethyl)-, 1-(2-chloroethyl)-3-cyclohexyl-, and 1-(2-chloroethyl)-3-(4'-
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Alkylation; Antineoplastic Agents; Carmustine; Chemical Phenomena; Chemistry; DNA; Lomustine; Nitrosourea Compounds; Semustine

1981
Analysis for nitrosourea antitumor agents by gas chromatography--mass spectrometry.
    Analytical chemistry, 1981, Volume: 53, Issue:8

    Topics: Animals; Antineoplastic Agents; Carmustine; Dogs; Gas Chromatography-Mass Spectrometry; Lomustine; Nitrosourea Compounds; Semustine

1981
Nephrotoxicity of nitrosoureas.
    Cancer, 1981, Sep-15, Volume: 48, Issue:6

    Topics: Adolescent; Adult; Aged; Biopsy; Blood Urea Nitrogen; Brain Neoplasms; Carmustine; Child; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Kidney; Kidney Diseases; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Retrospective Studies; Semustine

1981
Chronic toxicity and carcinogenicity of cytostatic N-nitroso-(2-chloroethyl) ureas after repeated intravenous application to rats.
    Developments in toxicology and environmental science, 1980, Volume: 8

    Topics: Animals; Antineoplastic Agents; Carcinogens; Carmustine; Lomustine; Lung Neoplasms; Male; Neoplasms, Experimental; Nervous System Neoplasms; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Semustine; Stomach Neoplasms

1980
Lipophilic drugs and lipoproteins: partitioning effects on chloroethylnitrosourea reaction rates in serum.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:2

    Topics: Carmustine; Humans; In Vitro Techniques; Kinetics; Lipids; Lipoproteins; Lomustine; Models, Biological; Nitrosourea Compounds; Semustine; Solubility

1980
Distribution of Bratton-Marshall-positive material in mice following intravenous injections of nitrosoureas.
    Cancer chemotherapy and pharmacology, 1980, Volume: 4, Issue:4

    Topics: Animals; Biotransformation; Carmustine; Colorimetry; Injections, Intravenous; Lomustine; Mice; Nitrosourea Compounds; Semustine; Tissue Distribution

1980
[Use of BCG as an immunoadjuvant in combination with antitumor agents in virus-induced leukemia].
    Bollettino della Societa italiana di biologia sperimentale, 1980, Oct-15, Volume: 56, Issue:19

    Topics: Animals; Antineoplastic Agents; BCG Vaccine; Carmustine; Drug Synergism; Drug Therapy, Combination; Hybridization, Genetic; Leukemia, Experimental; Lomustine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Moloney murine leukemia virus; Neoplasm Transplantation; Semustine; Time Factors

1980
Long term response to chemotherapy in patients with visceral metastatic melanoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Female; Humans; Interferon-alpha; Lomustine; Male; Melanoma; Middle Aged; Remission Induction; Semustine; Survival Rate

1994
Comparison of DNA lesions produced by tumor-inhibitory 1,2-bis(sulfonyl)hydrazines and chloroethylnitrosoureas.
    Biochemical pharmacology, 2000, Feb-01, Volume: 59, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Bacteriophage T7; Carmustine; Cross-Linking Reagents; DNA; DNA Damage; DNA, Viral; Isocyanates; Lomustine; Semustine

2000
Combined chemoradiation for the management of nasal natural killer (NK)/T-cell lymphoma: elucidating the significance of systemic chemotherapy.
    Oral oncology, 2008, Volume: 44, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Lomustine; Lymphoma, Extranodal NK-T-Cell; Male; Middle Aged; Nose Neoplasms; Retrospective Studies; Semustine; Survival Rate

2008
Molecular modeling and spectroscopic studies of semustine binding with DNA and its comparison with lomustine-DNA adduct formation.
    Journal of biomolecular structure & dynamics, 2015, Volume: 33, Issue:8

    Topics: Algorithms; Antineoplastic Agents, Alkylating; Circular Dichroism; DNA; DNA Adducts; Lomustine; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Semustine; Spectroscopy, Fourier Transform Infrared

2015