Page last updated: 2024-08-16

semustine and carmustine

semustine has been researched along with carmustine in 81 studies

Research

Studies (81)

TimeframeStudies, this research(%)All Research%
pre-199074 (91.36)18.7374
1990's4 (4.94)18.2507
2000's3 (3.70)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Clayton, SD; Frye, JL; Johnston, TP; Krauth, CA; McCaleb, GS; Montgomery, JA1
Johnston, TP; Laster, WR; Mayo, JG; McCaleb, GS; Montgomery, JA1
Bradner, WJ; Cassady, JM; Crider, AM; Floss, HG; Lamey, R1
Hansch, C; Jow, PY; Leo, A; Montgomery, JA; Schmidt, C1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Geran, RI; Mabel, JA; Merker, PC; Sturgeon, ML; Wodinsky, I1
Macdonald, JS; Schein, PS; Woolley, PV1
Walker, MD4
Eisenbrand, G; Fiebig, HH; Zeller, WJ1
Bono, VH1
Livingston, RB1
Basler, GA; Chernik, NL; Posner, JB; Shapiro, WR1
Bonadonna, G; Brambilla, C; Monfardini, S; Morello, G; Solero, CL; Vaghi, A; Valagussa, P1
Auletta, AE; Martz, AG; Parmar, AS1
Corbett, TH; Griswold, DP; Schabel, FM; Venditti, JM; Wolpert, MK1
Bhide, S; Habs, M; Reinbold, H; Schmähl, D1
Ghaffar, A; Lichter, W; Sigel, MM; Wellham, LL1
Twentyman, PR1
Bono, VH; Louie, AC; Muggia, FM; Turrisi, AT1
Dykes, DJ; Laster, WR; Rose, WC; Schabel, FM; Trader, MW1
Giles, GR; Lawton, JO1
Kisner, D; MacDonald, JS; Schein, PS1
Schabel, FM1
Ahmann, DL1
Wolf, J1
Bartolucci, A; Dorfman, RF; Durant, JR; Gams, RA; Velez-Garcia, E1
Carter, SK2
Levin, VA; Wilson, CB2
Oliverio, VT1
Moertel, CG1
Wasserman, TH1
Hilton, J; Walker, MD1
Balis, E; Brisman, R; Chang, C; Duffy, P; Housepian, EM1
Slavik, M1
Agradi, E; Paoletti, P; Pezzotta, S1
Luce, JK1
Drewinko, B; Gottlieb, JA; Loo, TL1
Dykes, DJ; Griswold, DP; Schabel, FM1
Camus, P; Coudert, B; Foucher, P; Jeannin, L; Lombard, JN; Massin, F; Reybet-Degat, O1
Boaziz, C; Breau, JL; Israël, L; Morere, JF1
Arita, N; Bitoh, S; Hasegawa, H; Hayakawa, T; Ikeda, H; Kanai, N; Kanoh, M; Mogami, H; Oku, Y; Ushio, Y1
Anderson, SP; Briscoe, WT; May, HE1
Bodell, WJ; Doane-Setzer, P; Evans, CG; Smith, MT; Tokuda, K1
Feola, JM; Maruyama, Y1
Eisenbrand, G; Krauth-Siegel, RL; Schirmer, RH; Stahl, W1
Giles, RC; Harrison, SD; Mann, DM1
Holden, SA; Rose, CM; Teicher, BA1
Barranco, SC; Ho, BY; Jenkins, VK; Koester, SK; Reumont, KJ; Townsend, CM1
Ozhiganov, EL; Platinskiĭ, LV; Sokolova, VD1
Adams, K; Peacock, JH; Stephens, TC1
Heim, ME; Queisser, W1
Wakui, A1
Glatte, P; Osieka, R; Pannenbäcker, R; Schmidt, CG1
Lee, FY; Workman, P1
Avellanosa, AM; Barua, NR; Hong, CI; Patel, A; West, CR1
Chang, CH; Horton, J; Kramer, S; Nelson, JS; Perez-Tamayo, R; Salazer, O; Schoenfeld, D; Tsukada, Y; Weinstein, A1
Lohrmann, HP1
Oguro, M; Takenaga, K; Yanagawa, T1
Shapiro, WR1
Ahlgren, JD; Schein, PS; Smith, FP; Woolley, PV1
Robak, T1
Gropp, C; Havemann, K1
Lepp, KA; Lohrmann, HP; Schreml, W1
Alexander, E; Batzdorf, U; Brooks, WH; Byar, DP; Green, SB; Hunt, WE; MacCarty, CS; Mahaley, MS; Mealey, J; Owens, G; Ransohoff, J; Robertson, JT; Shapiro, WR; Smith, KR; Strike, TA; Walker, MD; Wilson, CB1
Deen, DF; Weinkam, RJ1
Cowen, DM; Double, JA; Janik, AC; Siegerstetter, J1
Brandt, AE1
Chauhan, SM; Lown, JW1
Blackstock, SC; Cheung, LK; Loo, TL; Smith, RG1
Baldwin, DS; Feiner, HD; Gallo, GR; Lieberman, A; Schacht, RG1
Eisenbrand, G; Habs, M1
Finn, A; Kane, JP; Levin, VA; Weinkam, RJ1
Finkel, JM; Hill, DL; Kari, P; McConnell, WR1
Cenci, E; Perito, S; Sbaraglia, G; Vecchiarelli, A1
Penketh, PG; Sartorelli, AC; Shyam, K1
Kobiakov, GL1

Reviews

14 review(s) available for semustine and carmustine

ArticleYear
Chemotherapy of colorectal carcinoma.
    Seminars in oncology, 1976, Volume: 3, Issue:4

    Topics: Administration, Oral; Antineoplastic Agents; Carmustine; Colonic Neoplasms; Drug Administration Schedule; Drug Therapy, Combination; Floxuridine; Fluorouracil; Humans; Mitomycins; Perfusion; Rectal Neoplasms; Semustine; Time Factors

1976
Review of mechanism of action studies of the nitrosoureas.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Alkylating Agents; Animals; Bone Marrow; Bone Marrow Cells; Carmustine; Cell Division; Cell Survival; DNA; DNA, Neoplasm; Ethyl Chloride; Lomustine; Mice; NAD+ Nucleosidase; Neoplasms, Experimental; Nitrosourea Compounds; Protein Biosynthesis; RNA; Semustine; Streptozocin

1976
Treatment of brain tumors.
    The Medical clinics of North America, 1977, Volume: 61, Issue:5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Cell Division; Cell Survival; Clinical Trials as Topic; Glioblastoma; Glioma; Humans; Kinetics; Radiotherapy, High-Energy; Semustine

1977
Nitrosoureas: a review of experimental antitumor activity.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Animals; Carmustine; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Leukemia L1210; Lomustine; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Semustine

1976
Current protocol approaches in large bowel cancer.
    Seminars in oncology, 1976, Volume: 3, Issue:4

    Topics: Antineoplastic Agents; Carmustine; Clinical Trials as Topic; Colonic Neoplasms; Dacarbazine; Drug Therapy, Combination; Fluorouracil; Humans; Male; Mitomycins; Placebos; Rectal Neoplasms; Semustine

1976
Chemotherapy: the agents in current use.
    Seminars in oncology, 1975, Volume: 2, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Dacarbazine; Drug Therapy, Combination; Glioma; Humans; Lomustine; Medulloblastoma; Methotrexate; Nitrogen Mustard Compounds; Procarbazine; Semustine; Teniposide; Vincristine

1975
[Nitrosourea-induced lung diseases].
    Revue des maladies respiratoires, 1992, Volume: 9, Issue:6

    Topics: Adult; Brain Neoplasms; Carmustine; Child; Drug Therapy, Combination; Female; Humans; Iatrogenic Disease; Lomustine; Lung; Lung Diseases; Nitrosourea Compounds; Pneumonia; Prognosis; Pulmonary Fibrosis; Risk Factors; Semustine

1992
[Brain metastases of malignant melanomas].
    Bulletin du cancer, 1991, Volume: 78, Issue:4

    Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Dacarbazine; Humans; Interleukin-2; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Semustine

1991
[Chemotherapy of cancer of the large intestine].
    Sovetskaia meditsina, 1985, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colonic Neoplasms; Drug Evaluation; Fluorouracil; Humans; Lomustine; Melphalan; Methotrexate; Rectal Neoplasms; Semustine; Vincristine

1985
Chemotherapy in alimentary tract malignomas.
    Hepato-gastroenterology, 1981, Volume: 28, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carmustine; Colonic Neoplasms; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lomustine; Male; Methotrexate; Mitomycin; Mitomycins; Rectal Neoplasms; Semustine; Stomach Neoplasms; Streptozocin; Tegafur; Vincristine

1981
[Cancer chemotherapy with special reference to pharmacokinetics of nitrosoureas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:8

    Topics: Carmustine; Humans; Kinetics; Lomustine; Neoplasms; Nimustine; Nitrosourea Compounds; Semustine; Solubility; Streptozocin

1982
The problem of permanent bone marrow damage after cytotoxic drug treatment.
    Oncology, 1984, Volume: 41, Issue:3

    Topics: Animals; Antineoplastic Agents; Bone Marrow Diseases; Busulfan; Carmustine; Cell Division; Cell Survival; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Hematopoiesis; Hematopoietic Stem Cells; Humans; Melphalan; Semustine; Time Factors

1984
Treatment of neuroectodermal brain tumors.
    Annals of neurology, 1982, Volume: 12, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Therapy, Combination; Glioma; Humans; Lomustine; Middle Aged; Mitotic Index; Oligodendroglioma; Prospective Studies; Random Allocation; Semustine

1982
[Clinical significance of mustoforan in management of malignant glioma].
    Voprosy onkologii, 2007, Volume: 53, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Disease-Free Survival; Female; Glioblastoma; Glioma; Humans; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm, Residual; Nitrosourea Compounds; Oligodendroglioma; Organophosphorus Compounds; Semustine; Survival Analysis; Treatment Outcome

2007

Trials

16 trial(s) available for semustine and carmustine

ArticleYear
Chemotherapy: adjuvant to surgery and radiation therapy.
    Seminars in oncology, 1975, Volume: 2, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Fluorouracil; Glioma; Humans; Lomustine; Maryland; Plicamycin; Prospective Studies; Semustine; Vincristine

1975
Brain Tumor Study Group: a survey of current activities.
    National Cancer Institute monograph, 1977, Volume: 46

    Topics: Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Evaluation; Glioma; Humans; National Institutes of Health (U.S.); Plicamycin; Research Design; Semustine; United States

1977
Nitrosourea combinations in lung cancer.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Adenocarcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Carmustine; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Humans; Lomustine; Lung Neoplasms; Methotrexate; Nitrosourea Compounds; Semustine

1976
Treatment of brain tumors.
    The Medical clinics of North America, 1977, Volume: 61, Issue:5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Cell Division; Cell Survival; Clinical Trials as Topic; Glioblastoma; Glioma; Humans; Kinetics; Radiotherapy, High-Energy; Semustine

1977
Chemotherapy of large intestinal carcinoma. Current results and future prospects.
    Cancer, 1975, Volume: 36, Issue:6 Suppl

    Topics: Administration, Oral; Antineoplastic Agents; Carmustine; Clinical Trials as Topic; Colonic Neoplasms; Dacarbazine; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Humans; Injections, Intravenous; Rectal Neoplasms; Semustine; Vincristine

1975
Nitrosoureas in the management of disseminated malignant melanoma.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Carmustine; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Humans; Lomustine; Melanoma; Nitrosourea Compounds; Semustine

1976
Nitrosoureas as single agents in the treatment of pulmonary cancer.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Carmustine; Clinical Trials as Topic; Cyclophosphamide; Female; Humans; Lomustine; Lung Neoplasms; Male; Nitrosourea Compounds; Semustine

1976
Southeastern Cancer Study Group trials with nitrosoureas in Hodgkin's disease.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Administration, Oral; Carmustine; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Hodgkin Disease; Humans; Lomustine; Nitrosourea Compounds; Prednisone; Procarbazine; Semustine; Vinblastine

1976
Current protocol approaches in large bowel cancer.
    Seminars in oncology, 1976, Volume: 3, Issue:4

    Topics: Antineoplastic Agents; Carmustine; Clinical Trials as Topic; Colonic Neoplasms; Dacarbazine; Drug Therapy, Combination; Fluorouracil; Humans; Male; Mitomycins; Placebos; Rectal Neoplasms; Semustine

1976
Adjuvant nitrosourea therapy for glioblastoma.
    Archives of neurology, 1976, Volume: 33, Issue:11

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carmustine; Child; Child, Preschool; Drug Evaluation; Female; Glioma; Humans; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Semustine

1976
Chemotherapy of brain metastases from lung carcinoma: a controlled randomized study.
    Neurosurgery, 1991, Volume: 28, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Carmustine; Combined Modality Therapy; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nimustine; Radiotherapy Dosage; Remission Induction; Semustine; Survival Rate; Tegafur

1991
Comparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas. A joint Radiation Therapy Oncology Group and Eastern Cooperative Oncology Group study.
    Cancer, 1983, Sep-15, Volume: 52, Issue:6

    Topics: Adult; Age Factors; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Dacarbazine; Drug Therapy, Combination; Female; Glioma; Humans; Male; Middle Aged; Prednisone; Probability; Prognosis; Radiotherapy Dosage; Random Allocation; Semustine

1983
Treatment of neuroectodermal brain tumors.
    Annals of neurology, 1982, Volume: 12, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Therapy, Combination; Glioma; Humans; Lomustine; Middle Aged; Mitotic Index; Oligodendroglioma; Prospective Studies; Random Allocation; Semustine

1982
Current management of advanced and locally unresectable gastric carcinoma.
    Cancer, 1982, Dec-01, Volume: 50, Issue:11 Suppl

    Topics: Antineoplastic Agents; Carmustine; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Follow-Up Studies; Humans; Semustine; Stomach Neoplasms

1982
[Use of nitrosourea compounds in cancer chemotherapy].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1982, Sep-27, Volume: 37, Issue:36

    Topics: Carmustine; Clinical Trials as Topic; Humans; Lomustine; Neoplasms; Nitrosourea Compounds; Semustine

1982
Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery.
    The New England journal of medicine, 1980, Dec-04, Volume: 303, Issue:23

    Topics: Aged; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Drug Administration Schedule; Glioma; Humans; Middle Aged; Nitrosourea Compounds; Prognosis; Radiotherapy Dosage; Random Allocation; Semustine

1980

Other Studies

54 other study(ies) available for semustine and carmustine

ArticleYear
Synthesis of analogues of N-(2-chloroethyl)-N'-(trans-4-methylcyclohexyl)-N-nitrosourea for evaluation as anticancer agents.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:2

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Isomerism; Leukemia L1210; Mice; Mice, Inbred Strains; Nitrosourea Compounds; Semustine; Structure-Activity Relationship

1977
Inhibition of solid tumors by nitrosoureas. 1. Lewis lung carcinoma.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:2

    Topics: Animals; Carcinoma; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosourea Compounds; Structure-Activity Relationship; Time Factors

1977
Synthesis of nitrosourea derivatives of pyridine and piperidine as potential anticancer agents.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:8

    Topics: Animals; Antineoplastic Agents; Leukemia, Experimental; Leukopenia; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Piperidines; Pyridines; Structure-Activity Relationship

1980
Antitumor structure-activity relations. Nitrosoureas vs. L-1210 leukemia.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:10

    Topics: Animals; Antineoplastic Agents; Leukemia L1210; Mice; Models, Theoretical; Nitrosourea Compounds; Solubility; Structure-Activity Relationship

1980
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Combination chemotherapy against B16 melanoma: bleomycin/vinblastine, bleomycin/cis-diamminedichloroplatinum, 5-fluorouracil/BCNU and 5-fluorouracil/methyl-CCNU.
    Cancer, 1978, Volume: 42, Issue:4

    Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cisplatin; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Male; Melanoma; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Semustine; Vinblastine

1978
Examination of four newly synthesized 2-chloroethylnitrosoureas in comparison with BCNU, CCNU, MeCCNU, chlorozotocin and hydroxyethyl-CNU in preterminal rat leukemia L 5222.
    Journal of cancer research and clinical oncology, 1979, Volume: 95, Issue:1

    Topics: Animals; Carmustine; Drug Evaluation, Preclinical; Female; Leukemia, Experimental; Lomustine; Male; Nitrosourea Compounds; Rats; Semustine; Streptozocin

1979
Human brain tumor transplantation into nude mice.
    Journal of the National Cancer Institute, 1979, Volume: 62, Issue:3

    Topics: Animals; Brain Neoplasms; Carmustine; Glioblastoma; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Procarbazine; Semustine; Soft Tissue Neoplasms; Transplantation, Heterologous

1979
Adjuvant chemotherapy with nitrosourea compounds following surgery plus radiotherapy in glioblastoma multiforme.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1978, Volume: 68

    Topics: Brain Neoplasms; Carmustine; Glioblastoma; Humans; Lomustine; Nitrosourea Compounds; Semustine

1978
Mutagenicity of nitrosourea compounds for Salmonella typhimurium.
    Journal of the National Cancer Institute, 1978, Volume: 60, Issue:6

    Topics: Carmustine; Lomustine; Methods; Methylnitrosourea; Mutagens; Nitrosourea Compounds; Salmonella typhimurium; Semustine

1978
Design and evaluation of combination chemotherapy trials in experimental animal tumor systems.
    Cancer treatment reports, 1979, Volume: 63, Issue:5

    Topics: Animals; Antineoplastic Agents; Carmustine; Cisplatin; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Therapy, Combination; Evaluation Studies as Topic; Fluorouracil; Lomustine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasms, Experimental; Research Design; Semustine

1979
Antitumor activity of 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) and 1-(2-chloroethyl)-3-(4-methyl-cyclohexyl)-1-nitrosourea (MeCCNU) on Yoshida sarcoma ascites cells implanted into the colon wall of rats.
    Journal of cancer research and clinical oncology, 1979, May-14, Volume: 94, Issue:1

    Topics: Animals; Body Weight; Carmustine; Colonic Neoplasms; Cyclophosphamide; Male; Nitrosourea Compounds; Rats; Sarcoma, Yoshida; Semustine

1979
Effect of anticancer chemotherapeutic agents on immune reactions of mice. I. Comparison of two nitrosoureas: 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea.
    Journal of the National Cancer Institute, 1978, Volume: 60, Issue:6

    Topics: Animals; Antibody Formation; Antibody-Dependent Cell Cytotoxicity; Carmustine; Female; Immunity; Immunity, Cellular; Immunoglobulin G; Immunoglobulin M; Immunologic Memory; Immunosuppression Therapy; Lymphocyte Activation; Male; Mice; Nitrosourea Compounds; Semustine

1978
Sensitivity to 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea of the EMT6 tumor in vivo as determined by both tumor volume response and in vitro plating assay.
    Cancer research, 1978, Volume: 38, Issue:8

    Topics: Animals; Carmustine; Cell Count; Cell Cycle; Cell Survival; Clone Cells; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Nitrosourea Compounds; Semustine; Skin Neoplasms; Time Factors

1978
The contemporary role of chemotherapy in the treatment of malignant brain tumor.
    Clinical neurosurgery, 1978, Volume: 25

    Topics: Adrenal Cortex Hormones; Animals; Brain Neoplasms; Carmustine; Dose-Response Relationship, Drug; Drug Evaluation; Glioma; Humans; Inactivation, Metabolic; Lomustine; Neoplasms, Experimental; Prognosis; Radiotherapy Dosage; Semustine

1978
Visual abnormalities following nitrosourea treatment.
    Medical and pediatric oncology, 1978, Volume: 5, Issue:1

    Topics: Carmustine; Humans; Lomustine; Nitrosourea Compounds; Retina; Semustine; Vision Disorders; Visual Acuity

1978
Therapeutic potentiation of nitrosoureas using chlorpromazine and caffeine in the treatment of murine tumors.
    Cancer treatment reports, 1978, Volume: 62, Issue:12

    Topics: Animals; Caffeine; Carmustine; Chlorpromazine; Drug Synergism; Drug Therapy, Combination; Female; Leukemia L1210; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosourea Compounds; Semustine

1978
Chemotherapy for known residual disease after resection of gastric and colorectal cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1978, Volume: 68

    Topics: Carcinoembryonic Antigen; Carmustine; Colonic Neoplasms; Fluorouracil; Gastrointestinal Neoplasms; Humans; Neoplasm Recurrence, Local; Nitrosourea Compounds; Semustine; Stomach Neoplasms

1978
Pharmacology of the nitrosoureas: an overview.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Animals; Carmustine; Dogs; Half-Life; Haplorhini; Humans; Lomustine; Mice; Microsomes, Liver; Nitrosourea Compounds; Semustine

1976
Gastrointestinal cancer. Treatment with fluorouracil-nitrosourea combinations.
    JAMA, 1976, May-10, Volume: 235, Issue:19

    Topics: Carmustine; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Lomustine; Male; Methods; Nitrosourea Compounds; Pancreatic Neoplasms; Rectal Neoplasms; Remission, Spontaneous; Semustine; Stomach Neoplasms

1976
The nitrosoureas: an outline of clinical schedules and toxic effects.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Administration, Oral; Bone Marrow; Capsules; Carmustine; Humans; Injections, Intravenous; Lomustine; Nausea; Nitrosourea Compounds; Semustine

1976
Nitrosourea chemotherapy for primary malignant gliomas.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Brain Neoplasms; Carmustine; Drug Therapy, Combination; Fluorouracil; Glioma; Humans; Lomustine; Neoplasm Recurrence, Local; Nitrosourea Compounds; Procarbazine; Semustine; Vincristine

1976
Nitrosourea pharmacodynamics in relation to the central nervous system.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Glioma; Humans; Lomustine; Mice; Molecular Weight; Neoplasms, Experimental; Nitrosourea Compounds; Semustine; Solubility

1976
Clinical studies with nitrosoureas in various solid tumors.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Squamous Cell; Carmustine; Female; Genital Neoplasms, Female; Head and Neck Neoplasms; Humans; Kidney Neoplasms; Lomustine; Male; Neoplasms; Nitrosourea Compounds; Sarcoma; Semustine; Testicular Neoplasms

1976
The effect of BCNU, CCNU and MeCCNU in the prevention of the development of tumors of the nervous system.
    Pharmacological research communications, 1975, Volume: 07, Issue:1

    Topics: Animals; Brain Neoplasms; Carmustine; Ethylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Semustine

1975
Chemotherapy of melanoma.
    Seminars in oncology, 1975, Volume: 2, Issue:2

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carmustine; Cyclophosphamide; Dacarbazine; Dactinomycin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Semustine; Skin Neoplasms; Vinca Alkaloids

1975
Editorial: Large-bowel cancer-The current status of treatment.
    Journal of the National Cancer Institute, 1976, Volume: 56, Issue:1

    Topics: Adjuvants, Immunologic; BCG Vaccine; Carmustine; Colonic Neoplasms; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Immunotherapy; Lomustine; Mitomycins; Neoplasm Metastasis; Neoplasm Recurrence, Local; Rectal Neoplasms; Semustine; United States

1976
A comparison of the lethal effects of three nitrosourea derivatives on cultured human lymphoma cells.
    Cancer research, 1976, Volume: 36, Issue:2 Pt 1

    Topics: Amphotericin B; Carmustine; Cell Line; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Lomustine; Lymphoma; Neoplasms, Experimental; Nitrosourea Compounds; Semustine; Time Factors; Vitamin A

1976
Growth support of small B16 melanoma implants with nitrosourea-sterilized fractions of the same tumor.
    Cancer research, 1976, Volume: 36, Issue:6

    Topics: Animals; Carmustine; Cell Line; Cells, Cultured; Melanoma; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Radiation Effects; Semustine; Time Factors

1976
Base sequence specificity of three 2-chloroethylnitrosoureas.
    Biochemical pharmacology, 1990, Sep-15, Volume: 40, Issue:6

    Topics: Alkylation; Base Sequence; Carmustine; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; DNA; Guanine; Lomustine; Nitrosourea Compounds; Semustine; Structure-Activity Relationship

1990
Glutathione and related enzymes in rat brain tumor cell resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea and nitrogen mustard.
    Cancer research, 1987, May-15, Volume: 47, Issue:10

    Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Carmustine; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Clone Cells; Dinitrochlorobenzene; Drug Resistance; gamma-Glutamyltransferase; Glioma; Glutathione; Glutathione Transferase; Lomustine; Mechlorethamine; Methionine Sulfoximine; Rats; Semustine

1987
Cure rates and tumor resistance in cured mice after nitrosourea treatment of EMT6 ascites tumors.
    Oncology, 1986, Volume: 43, Issue:6

    Topics: Animals; Antineoplastic Agents; Carmustine; Drug Resistance; Female; Lethal Dose 50; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Nitrosourea Compounds; Semustine; Streptozocin

1986
A method to determine the carbamoylating potential of 1-(2-chloroethyl)-1-nitrosoureas.
    IARC scientific publications, 1987, Issue:84

    Topics: Alkylating Agents; Carbamates; Carmustine; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Dithionitrobenzoic Acid; Ethylnitrosourea; Glutathione; Humans; Nitrosourea Compounds; Semustine; Streptozocin

1987
Effect of nitrosoureas on calmodulin activity in vitro and in mouse intestine in vivo.
    Cancer chemotherapy and pharmacology, 1985, Volume: 14, Issue:2

    Topics: Animals; Calcium; Calmodulin; Carmustine; Cattle; Cyanates; Cyclic AMP; Intestinal Mucosa; Intestines; Lomustine; Male; Mice; Nitrosourea Compounds; Phosphoric Diester Hydrolases; Semustine; Streptozocin

1985
Effect of Fluosol-DA/O2 on tumor-cell and bone-marrow cytotoxicity of nitrosoureas in mice bearing FSA-II fibrosarcoma.
    International journal of cancer, 1986, Aug-15, Volume: 38, Issue:2

    Topics: Animals; Bone Marrow; Carbon Dioxide; Carmustine; Cell Survival; Drug Combinations; Fibrosarcoma; Fluorocarbons; Hydroxyethyl Starch Derivatives; Lomustine; Male; Mice; Mice, Inbred C3H; Nitrosourea Compounds; Oxygen; Semustine

1986
Changes in drug sensitivity of a human astrocytoma clone previously treated with 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea in vitro.
    Investigational new drugs, 1988, Volume: 6, Issue:4

    Topics: Astrocytoma; Carmustine; Cell Survival; Clone Cells; Doxorubicin; Drug Resistance; Galactitol; Humans; Semustine

1988
Emergence of nitrosourea resistant sublines of Lewis lung tumour following MeCCNU treatment in vivo.
    British journal of cancer, 1986, Volume: 53, Issue:2

    Topics: Animals; Carmustine; Cell Line; Cell Survival; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Resistance; Lomustine; Lung Neoplasms; Melphalan; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Nitrosourea Compounds; Semustine; Time Factors

1986
Therapeutic evaluation of five nitrosoureas in a human melanoma xenograft system.
    Cancer chemotherapy and pharmacology, 1983, Volume: 11, Issue:3

    Topics: Animals; Bone Marrow; Brain Neoplasms; Carmustine; Dose-Response Relationship, Drug; Female; Humans; Lomustine; Male; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Nitrosourea Compounds; Semustine; Streptozocin; Transplantation Immunology; Transplantation, Heterologous

1983
Nitroimidazoles as modifiers of nitrosourea pharmacokinetics.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9

    Topics: Animals; Antineoplastic Agents; Carmustine; Lomustine; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Nitrosourea Compounds; Radiation-Sensitizing Agents; Semustine; Streptozocin; Time Factors

1984
Intraarterial 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and systemic chemotherapy for malignant gliomas: a follow-up study.
    Neurosurgery, 1983, Volume: 13, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Carotid Artery, Internal; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Procarbazine; Prognosis; Semustine; Vincristine

1983
[Antitumor activity of a new nitrosourea, MCNU, on a cellular morphological basis evaluated by a new in vitro antitumor sensitivity assay].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:12 Pt 1

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Humans; In Vitro Techniques; Leukemia L1210; Lomustine; Nimustine; Nitrosourea Compounds; Semustine; Tumor Stem Cell Assay

1984
[Chemotherapy of stomach cancer].
    Zeitschrift fur Gastroenterologie, 1982, Volume: 20, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Agents; Carmustine; Cisplatin; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Gastrectomy; Humans; Lomustine; Mitomycin; Mitomycins; Neoplasm Recurrence, Local; Prognosis; Semustine; Stomach Neoplasms

1982
5-Fluorouracil, 1,3-bis(2-chloroethyl)-1-nitrosourea, and 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea: effect on the human granulopoietic system.
    Journal of the National Cancer Institute, 1982, Volume: 68, Issue:4

    Topics: Adult; Aged; Bone Marrow; Carmustine; Cell Count; Cell Division; Fluorouracil; Granulocytes; Hematopoiesis; Hematopoietic Stem Cells; Humans; Middle Aged; Nitrosourea Compounds; Semustine; Time Factors

1982
Quantitative dose-response relations for the cytotoxic activity of chloroethylnitrosoureas in cell culture.
    Cancer research, 1982, Volume: 42, Issue:3

    Topics: Animals; Biotransformation; Brain Neoplasms; Carmustine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Lomustine; Mustard Compounds; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Semustine; Structure-Activity Relationship; Time Factors

1982
The assessment of response of murine transplantable colon tumors to combination chemotherapy.
    Journal of cancer research and clinical oncology, 1982, Volume: 103, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carmustine; Cell Line; Colonic Neoplasms; Dimethylhydrazines; Drug Therapy, Combination; Fluorouracil; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Semustine

1982
Correspondence re: J. H. Pincus, A. K. Jameson, and A. E. Brandt. Immunotherapy of L1210 leukemia using neuraminidase-modified plasma membranes combined with chemotherapy. Cancer Res., 41: 3082-3086, 1981.
    Cancer research, 1982, Volume: 42, Issue:10

    Topics: Animals; Carmustine; Cell Membrane; Immunotherapy; Leukemia L1210; Mice; Neuraminidase; Semustine

1982
Mechanism of action of (2-haloethyl)nitrosoureas on DNA. Isolation and reactions of postulated 2-(alkylimino)-3-nitrosooxazolidine intermediates in the decomposition of 1,3-bis(2-chloroethyl)-, 1-(2-chloroethyl)-3-cyclohexyl-, and 1-(2-chloroethyl)-3-(4'-
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Alkylation; Antineoplastic Agents; Carmustine; Chemical Phenomena; Chemistry; DNA; Lomustine; Nitrosourea Compounds; Semustine

1981
Analysis for nitrosourea antitumor agents by gas chromatography--mass spectrometry.
    Analytical chemistry, 1981, Volume: 53, Issue:8

    Topics: Animals; Antineoplastic Agents; Carmustine; Dogs; Gas Chromatography-Mass Spectrometry; Lomustine; Nitrosourea Compounds; Semustine

1981
Nephrotoxicity of nitrosoureas.
    Cancer, 1981, Sep-15, Volume: 48, Issue:6

    Topics: Adolescent; Adult; Aged; Biopsy; Blood Urea Nitrogen; Brain Neoplasms; Carmustine; Child; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Kidney; Kidney Diseases; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Retrospective Studies; Semustine

1981
Chronic toxicity and carcinogenicity of cytostatic N-nitroso-(2-chloroethyl) ureas after repeated intravenous application to rats.
    Developments in toxicology and environmental science, 1980, Volume: 8

    Topics: Animals; Antineoplastic Agents; Carcinogens; Carmustine; Lomustine; Lung Neoplasms; Male; Neoplasms, Experimental; Nervous System Neoplasms; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Semustine; Stomach Neoplasms

1980
Lipophilic drugs and lipoproteins: partitioning effects on chloroethylnitrosourea reaction rates in serum.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:2

    Topics: Carmustine; Humans; In Vitro Techniques; Kinetics; Lipids; Lipoproteins; Lomustine; Models, Biological; Nitrosourea Compounds; Semustine; Solubility

1980
Distribution of Bratton-Marshall-positive material in mice following intravenous injections of nitrosoureas.
    Cancer chemotherapy and pharmacology, 1980, Volume: 4, Issue:4

    Topics: Animals; Biotransformation; Carmustine; Colorimetry; Injections, Intravenous; Lomustine; Mice; Nitrosourea Compounds; Semustine; Tissue Distribution

1980
[Use of BCG as an immunoadjuvant in combination with antitumor agents in virus-induced leukemia].
    Bollettino della Societa italiana di biologia sperimentale, 1980, Oct-15, Volume: 56, Issue:19

    Topics: Animals; Antineoplastic Agents; BCG Vaccine; Carmustine; Drug Synergism; Drug Therapy, Combination; Hybridization, Genetic; Leukemia, Experimental; Lomustine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Moloney murine leukemia virus; Neoplasm Transplantation; Semustine; Time Factors

1980
Comparison of DNA lesions produced by tumor-inhibitory 1,2-bis(sulfonyl)hydrazines and chloroethylnitrosoureas.
    Biochemical pharmacology, 2000, Feb-01, Volume: 59, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Bacteriophage T7; Carmustine; Cross-Linking Reagents; DNA; DNA Damage; DNA, Viral; Isocyanates; Lomustine; Semustine

2000
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