selfotel has been researched along with dizocilpine maleate in 83 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (2.41) | 18.7374 |
| 1990's | 70 (84.34) | 18.2507 |
| 2000's | 10 (12.05) | 29.6817 |
| 2010's | 1 (1.20) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nellgård, B; Wieloch, T | 1 |
| Nicklas, WJ; Zeevalk, GD | 1 |
| Morimoto, K; Sato, M | 1 |
| Dichter, MA; Molinoff, PB; Williams, K | 1 |
| Bonaventure, N; Jardon, B | 1 |
| Matsuda, Y; Nonaka, H; Nozawa, M; Toki, S; Tsukuda, E; Yoshida, M | 1 |
| Colombo, G; Grant, KA | 2 |
| Ohno, M; Ueki, S; Watanabe, S; Yamamoto, T | 1 |
| Bättig, K; Berz, S; Welzl, H | 1 |
| Calder, LD; Karler, R | 1 |
| Heikkila, RE; Riordan, DE; Sonsalla, PK | 1 |
| Choi, DW; Zivin, JA | 1 |
| Millan, MJ | 1 |
| Crain, BJ; Nadler, JV; Neill, KH; Warner, MA | 1 |
| Liljequist, S | 1 |
| Mansbach, RS | 1 |
| Inoue, K; Katayama, K; Morimoto, K; Sato, K | 1 |
| Aizenman, E; Reynolds, IJ; Rush, EA | 1 |
| Crain, BJ; Nadler, JV; Warner, MA | 1 |
| Parada-Turska, J; Turski, WA | 1 |
| Kim, HS; Lehmann, J; Martin, LL; Rao, TS; Wood, PL | 1 |
| Meldrum, BS; Swan, JH | 1 |
| Dziki, M; Ikonomidou, C; Parada-Turska, J; Turski, WA; Urbanska, E | 1 |
| Hillman, CC; Ornstein, PL; Salhoff, CR; Schoepp, DD | 1 |
| France, CP; Ornstein, P; Woods, JH | 1 |
| Payne, RS; Rigor, BM; Schurr, A | 1 |
| Fedele, E; Raiteri, M; Versace, P | 1 |
| Farfel, GM; Seiden, LS | 1 |
| Hoffman, PL; Iorio, KR; Snell, LD; Tabakoff, B | 1 |
| Calligaro, DO; Monn, JA; O'Malley, PJ | 1 |
| Fagg, GE; Massieu, L; McVey, M; Thedinga, KH | 1 |
| Abraham, J; Aronstam, RS; Dennison, RL; Martin, DC; Plagenhoef, M | 1 |
| Ferkany, JW; Karbon, EW; Price, CH; Saab, OH; Sweetnam, PM; Wroblewski, JT | 1 |
| Pèzzola, A; Popoli, P; Sagratella, S | 1 |
| Allegrini, PR; Fagg, GE; Sauer, D | 1 |
| Aizenman, E; Blitzblau, RC; Hartnett, KA; Rosenberg, PA; Speliotes, EK | 1 |
| Butcher, SP; Kelly, JS; Ritchie, IM; Sharkey, J | 2 |
| Bullock, R; Fujisawa, H; Graham, DI; Kuroda, Y; Strebel, S | 1 |
| Scatton, B | 1 |
| Breese, GR; Criswell, HE; Johnson, KB; Mueller, RA | 1 |
| Jeziorski, M; White, FJ; Wolf, ME | 1 |
| Bullock, R; Kuroda, Y; Rafferty, C; Strebel, S | 1 |
| Berge, OG; Karlsson, U; Näsström, J | 1 |
| Chan, P; Di Monte, DA; Langston, JW | 1 |
| Berge, OG; Böö, E; Näsström, J; Ståhlberg, M | 1 |
| French, ED; Mura, A; Wang, T | 1 |
| Lookingland, KJ; Moore, KE; Wagner, EJ | 1 |
| Dourish, CT; McLenachan, AP; Stanhope, KJ | 1 |
| Finnegan, KT; Taraska, T | 1 |
| Li, HB; Matsumoto, K; Tohda, M; Watanabe, H; Yamamoto, M | 2 |
| Hao, JX; Xu, XJ | 1 |
| Lu, X; Sinha, AK; Weiss, HR | 1 |
| Aizenman, E; Boeckman, FA | 1 |
| Grass, S; Hoffmann, O; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
| Elliott, KJ; Gorman, AL; Inturrisi, CE | 1 |
| Chen, J; Graham, SH; Lan, JQ; Sharp, FR; Simon, RP | 1 |
| Kirsch, JR; Koehler, RC; Miyabe, M; Nishikawa, T; Traystman, RJ | 1 |
| Dalton, ML; Gadson, PF; Rosenquist, TH; Wrenn, RW | 1 |
| Li, HB; Matsumoto, K; Watanabe, H; Yamamoto, M | 1 |
| Ashby, CR; Katsumori, H; Minabe, Y; Osawa, M | 1 |
| Löscher, W; Szabo, L; Wlaź, P | 1 |
| Bélanger, MC; Burhan, AM; Sadikot, AF; Sasseville, R | 1 |
| Ganguly, A; Keefe, KA | 1 |
| Li, H; Matsumoto, K; Watanabe, H | 1 |
| Adams, AC; Keefe, KA | 2 |
| Arias, RL; Bowlby, MR; Tasse, JR | 1 |
| Butelman, ER; Campbell, CM; Woods, JH | 1 |
| Li, Y; Wolf, ME | 1 |
| Basarsky, TA; Feighan, D; MacVicar, BA | 1 |
| Balcar, VJ; FitzGibbon, T; Lawrance, ML; Pliss, L; Shave, E; Stastny, F | 1 |
| Gemignani, A; Paudice, P; Pittaluga, A; Raiteri, M | 1 |
| Balcar, VJ; FitzGibbon, T; Pliss, L; St'astný, F | 1 |
| Cho, Y; Mori, A; Shimizu, H; Ueda, T; Yozu, R | 1 |
| Fowler, CJ; Jacobsson, SO; Nilsson, O | 1 |
| Bado, M; Grilli, M; Marchi, M; Parodi, M; Raiteri, M; Risso, F | 1 |
| Schurr, A | 1 |
| Ichitani, Y; Iwasaki, T; Kawabe, K | 1 |
| Grilli, M; Marchi, M; Merlo-Pich, E; Pittaluga, A | 1 |
| Gunkel, BT; Hughes, MN; Prior, NA; Rogers, KK; Yates, JR | 1 |
2 review(s) available for selfotel and dizocilpine maleate
| Article | Year |
|---|---|
Excitatory amino acid receptor antagonists: a novel treatment for ischemic cerebrovascular diseases.
Topics: Animals; Brain Ischemia; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Humans; Pipecolic Acids; Piperidines; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1994 |
Neuroprotection against ischemic/hypoxic brain damage: blockers of ionotropic glutamate receptor and voltage sensitive calcium channels.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Diltiazem; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Hypoxia-Ischemia, Brain; Neuroprotective Agents; Pipecolic Acids; Rats; Receptors, Glutamate | 2004 |
1 trial(s) available for selfotel and dizocilpine maleate
| Article | Year |
|---|---|
Stroke therapy.
Topics: Animals; Arterial Occlusive Diseases; Calcium; Cell Survival; Cerebral Arterial Diseases; Cerebrovascular Disorders; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Humans; Intracranial Embolism and Thrombosis; Neurons; Pipecolic Acids; Receptors, N-Methyl-D-Aspartate; Tissue Plasminogen Activator; Tomography, Emission-Computed | 1991 |
80 other study(ies) available for selfotel and dizocilpine maleate
| Article | Year |
|---|---|
NMDA-receptor blockers but not NBQX, an AMPA-receptor antagonist, inhibit spreading depression in the rat brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Cell Membrane Permeability; Cortical Spreading Depression; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists; Ion Channels; Male; Pipecolic Acids; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1992 |
Developmental differences in antagonism of NMDA toxicity by the polyamine site antagonist ifenprodil.
Topics: Amino Acids; Animals; Biogenic Polyamines; Chick Embryo; Dizocilpine Maleate; Kynurenic Acid; N-Methylaspartate; Pipecolic Acids; Piperidines; Receptors, Glutamate; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Retina | 1992 |
NMDA receptor complex and kindling mechanisms.
Topics: Amygdala; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Hippocampus; Kindling, Neurologic; Kynurenic Acid; Male; Neural Pathways; Pipecolic Acids; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1992 |
Up-regulation of N-methyl-D-aspartate receptors on cultured cortical neurons after exposure to antagonists.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Neurons; Pipecolic Acids; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Up-Regulation | 1992 |
N-methyl-D-aspartate antagonists suppress the development of frog symmetric monocular optokynetic nystagmus observed after unilateral visual deprivation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Injections, Intraperitoneal; Magnetics; Microinjections; N-Methylaspartate; Nystagmus, Physiologic; Pipecolic Acids; Rana esculenta; Receptors, N-Methyl-D-Aspartate; Vision, Monocular | 1992 |
The ES-242s, novel N-methyl-D-aspartate antagonists of microbial origin, interact with both the neurotransmitter recognition site and the ion channel domain.
Topics: Animals; Binding, Competitive; Biological Transport; Calcium; Cells, Cultured; Cyclic GMP; Dizocilpine Maleate; Hippocampus; Ion Channels; Kinetics; Mice; N-Methylaspartate; Neurons; Neurotransmitter Agents; Phencyclidine; Pipecolic Acids; Pyrans; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes | 1992 |
NMDA receptor complex antagonists have ethanol-like discriminative stimulus effects.
Topics: Animals; Discrimination, Psychological; Dizocilpine Maleate; Ethanol; Phencyclidine; Pipecolic Acids; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Reinforcement, Psychology | 1992 |
Protection by N-methyl-D-aspartate receptor antagonists against impairment of working memory in rats following transient cerebral ischemia.
Topics: Animals; Dextrorphan; Dizocilpine Maleate; Ischemic Attack, Transient; Memory; N-Methylaspartate; Pipecolic Acids; Prosencephalon; Rats; Receptors, N-Methyl-D-Aspartate | 1992 |
Effects of CGS 19755 and dizocilpine (MK 801) on delayed time discrimination performance.
Topics: Animals; Conditioning, Operant; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Male; Mental Recall; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule; Time Perception | 1992 |
Excitatory amino acids and the actions of cocaine.
Topics: Animals; Caffeine; Cocaine; Dextromethorphan; Dizocilpine Maleate; Haloperidol; Male; Mice; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Pipecolic Acids; Quinoxalines; Rats; Rats, Inbred Strains; Seizures; Stereoisomerism; Stereotyped Behavior | 1992 |
Competitive and noncompetitive antagonists at N-methyl-D-aspartate receptors protect against methamphetamine-induced dopaminergic damage in mice.
Topics: Amino Acids; Animals; Corpus Striatum; Dizocilpine Maleate; Male; Methamphetamine; Mice; N-Methylaspartate; Pipecolic Acids; Piperidines; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Tyrosine 3-Monooxygenase | 1991 |
Antagonists at the NMDA recognition site and blockers of the associated ion channel induce spontaneous tail-flicks in the rat.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ion Channels; Ketamine; Male; N-Methylaspartate; Organophosphorus Compounds; Phencyclidine; Pipecolic Acids; Piperazines; Piperidines; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Regionally selective effects of NMDA receptor antagonists against ischemic brain damage in the gerbil.
Topics: Animals; Body Temperature; Brain; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Male; Neurons; Pipecolic Acids; Receptors, N-Methyl-D-Aspartate; Triazoles | 1991 |
Genetic differences in the effects of competitive and non-competitive NMDA receptor antagonists on locomotor activity in mice.
Topics: Amino Acids; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ketamine; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Motor Activity; Phencyclidine; Pipecolic Acids; Receptors, N-Methyl-D-Aspartate; Species Specificity | 1991 |
Effects of NMDA receptor ligands on sensorimotor gating in the rat.
Topics: Acoustic Stimulation; Amino Acids; Animals; Dizocilpine Maleate; Ligands; Male; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Reflex; Reflex, Startle | 1991 |
Effects of competitive and noncompetitive NMDA receptor antagonists on kindling and LTP.
Topics: Animals; Binding, Competitive; Dizocilpine Maleate; Electric Stimulation; Evoked Potentials; Kindling, Neurologic; Male; Neuronal Plasticity; Pipecolic Acids; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Reduction of NMDA receptors with dithiothreitol increases [3H]-MK-801 binding and NMDA-induced Ca2+ fluxes.
Topics: Animals; Calcium; Dithionitrobenzoic Acid; Dithiothreitol; Dizocilpine Maleate; Fluorescence; Fura-2; Glutamates; Glycine; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Pipecolic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine | 1990 |
Effects of NMDA receptor antagonists and body temperature in the gerbil carotid occlusion model of transient forebrain ischemia.
Topics: Animals; Anticonvulsants; Body Temperature; Brain; Brain Diseases; Carotid Arteries; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Gerbillinae; Hippocampus; Hypothermia; Ischemic Attack, Transient; Male; Pipecolic Acids; Pyramidal Tracts; Receptors, N-Methyl-D-Aspartate; Triazoles | 1990 |
Excitatory amino acid antagonists and memory: effect of drugs acting at N-methyl-D-aspartate receptors in learning and memory tasks.
Topics: Animals; Avoidance Learning; Dizocilpine Maleate; Male; Memory; Mice; Motor Activity; N-Methylaspartate; Pipecolic Acids; Piperazines; Receptors, N-Methyl-D-Aspartate; Reference Values | 1990 |
Selective activation of dopaminergic pathways in the mesocortex by compounds that act at the phencyclidine (PCP) binding site: tentative evidence for PCP recognition sites not coupled to N-methyl-D-aspartate (NMDA) receptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Carbazoles; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Guanidines; Ligands; Male; Neural Pathways; Pipecolic Acids; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Stereoisomerism | 1990 |
Protection by NMDA antagonists against selective cell loss following transient ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Brain Ischemia; Dibenzocycloheptenes; Dizocilpine Maleate; Male; N-Methylaspartate; Neurons; Pipecolic Acids; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Excitatory amino acid antagonists protect mice against seizures induced by bicuculline.
Topics: Animals; Bicuculline; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mice; Muscimol; Pipecolic Acids; Piperazines; Piperidines; Receptors, Amino Acid; Receptors, Cell Surface; Seizures | 1990 |
CGS-19755 and MK-801 selectively prevent rat striatal cholinergic and gabaergic neuronal degeneration induced by N-methyl-D-aspartate and ibotenate in vivo.
Topics: Animals; Aspartic Acid; Choline O-Acetyltransferase; Cholinergic Fibers; Corpus Striatum; Dibenzocycloheptenes; Dizocilpine Maleate; gamma-Aminobutyric Acid; Ibotenic Acid; Male; N-Methylaspartate; Nerve Degeneration; Oxazoles; Pipecolic Acids; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
The competitive N-methyl-D-aspartate (NMDA) antagonist CGS 19755 attenuates the rate-decreasing effects of NMDA in rhesus monkeys without producing ketamine-like discriminative stimulus effects.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Discrimination, Psychological; Dizocilpine Maleate; Ketamine; Macaca mulatta; Male; N-Methylaspartate; Pipecolic Acids; Piperidines | 1989 |
Protection by MK-801 against hypoxia-, excitotoxin-, and depolarization-induced neuronal damage in vitro.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anti-Anxiety Agents; Benzodiazepines; Diltiazem; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Kynurenic Acid; Membrane Potentials; Neurons; Nifedipine; Pipecolic Acids; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1995 |
Evaluation of the mechanisms underlying the kainate-induced impairment of [3H]dopamine release in the rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Electric Stimulation; Kainic Acid; Ketamine; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons, Afferent; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley | 1993 |
Role of hypothermia in the mechanism of protection against serotonergic toxicity. I. Experiments using 3,4-methylenedioxymethamphetamine, dizocilpine, CGS 19755 and NBQX.
Topics: Animals; Body Temperature; Brain Chemistry; Dizocilpine Maleate; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin | 1995 |
Attenuation of glutamate-induced neurotoxicity in chronically ethanol-exposed cerebellar granule cells by NMDA receptor antagonists and ganglioside GM1.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; G(M1) Ganglioside; Glutamic Acid; Kynurenic Acid; Neurons; Pipecolic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Up-Regulation | 1995 |
beta-Amyloid (25-35) or substance P stimulates [3H]MK-801 binding to rat cortical membranes in the presence of glutamate and glycine.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Animals; Biguanides; Cell Membrane; Cerebral Cortex; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Kinetics; Molecular Sequence Data; N-Methylaspartate; Peptide Fragments; Pipecolic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Sequence Homology, Amino Acid; Substance P | 1993 |
A comparative analysis of the neuroprotective properties of competitive and uncompetitive N-methyl-D-aspartate receptor antagonists in vivo: implications for the process of excitotoxic degeneration and its therapy.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Biomarkers; Cell Death; Choline O-Acetyltransferase; Corpus Striatum; Dizocilpine Maleate; Drug Administration Schedule; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Injections; Injections, Intraperitoneal; Kainic Acid; Male; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neurotoxins; Pipecolic Acids; Piperazines; Quinolinic Acid; Rats; Receptors, N-Methyl-D-Aspartate | 1993 |
Volatile anesthetics and glutamate activation of N-methyl-D-aspartate receptors.
Topics: Anesthetics, Inhalation; Animals; Dizocilpine Maleate; Glutamic Acid; Glycine; Male; Pipecolic Acids; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1995 |
The envelope glycoprotein of HIV-1 alters NMDA receptor function.
Topics: Animals; Calcium Channel Blockers; Cells, Cultured; Dizocilpine Maleate; Electrophysiology; HIV Envelope Protein gp120; N-Methylaspartate; Oocytes; Phencyclidine; Pipecolic Acids; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Xenopus | 1993 |
Diphenylhydantoin potentiates the EEG and behavioural effects induced by N-methyl-D-aspartate antagonists in rats.
Topics: Animals; Behavior, Animal; Cortical Synchronization; Dizocilpine Maleate; Drug Synergism; Electroencephalography; Male; N-Methylaspartate; Phencyclidine; Phenytoin; Pipecolic Acids; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1994 |
The competitive NMDA receptor antagonist CGP 40116 is a potent neuroprotectant in a rat model of focal cerebral ischemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Brain Ischemia; Dizocilpine Maleate; Dose-Response Relationship, Drug; Magnetic Resonance Imaging; Male; Neuroprotective Agents; Pipecolic Acids; Piperazines; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate | 1994 |
Comparison of the potency of competitive NMDA antagonists against the neurotoxicity of glutamate and NMDA.
Topics: 2-Amino-5-phosphonovalerate; Animals; Astrocytes; Binding, Competitive; Cell Survival; Cells, Cultured; Cerebral Cortex; Dendrites; Dizocilpine Maleate; Embryo, Mammalian; Glutamates; Glutamic Acid; N-Methylaspartate; Neurons; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Differential effects of competitive (CGS19755) and non-competitive (MK 801) NMDA receptor antagonists upon local cerebral blood flow and local cerebral glucose utilisation in the rat.
Topics: Animals; Brain; Cerebrovascular Circulation; Dizocilpine Maleate; Glucose; Male; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Effect of neuroprotective N-methyl-D-aspartate antagonists on increased intracranial pressure: studies in the rat acute subdural hematoma model.
Topics: Acute Disease; Animals; Disease Models, Animal; Dizocilpine Maleate; Hematoma, Subdural; Hemodynamics; Intracranial Pressure; Male; Mannitol; N-Methylaspartate; Pipecolic Acids; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Evidence for involvement of brain dopamine and other mechanisms in the behavioral action of the N-methyl-D-aspartic acid antagonist MK-801 in control and 6-hydroxydopamine-lesioned rats.
Topics: alpha-Methyltyrosine; Animals; Animals, Newborn; Behavior, Animal; Brain; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Female; Gene Expression; Genes, fos; Levodopa; Male; Methyltyrosines; N-Methylaspartate; Pipecolic Acids; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Serotonin; Tyrosine 3-Monooxygenase | 1993 |
MK-801 prevents the development of behavioral sensitization during repeated morphine administration.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Male; Morphine; Motor Activity; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Neuroprotective doses of N-methyl-D-aspartate receptor antagonists profoundly reduce the minimum alveolar anesthetic concentration (MAC) for isoflurane in rats.
Topics: Anesthesia, Inhalation; Animals; Dizocilpine Maleate; Isoflurane; Male; Pipecolic Acids; Piperazines; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Systemic or intracerebroventricular injection of NMDA receptor antagonists attenuates the antinociceptive activity of intrathecally administered NMDA receptor antagonists.
Topics: Animals; Cerebral Ventricles; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hot Temperature; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Spinal; Mice; Mice, Inbred Strains; N-Methylaspartate; Pain; Pipecolic Acids; Receptors, N-Methyl-D-Aspartate; Skin Temperature; Spinal Cord; Time Factors | 1993 |
MK-801 temporarily prevents MPTP-induced acute dopamine depletion and MPP+ elimination in the mouse striatum.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Drug Interactions; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Pipecolic Acids; Time Factors | 1993 |
Tissue distribution of two NMDA receptor antagonists, [3H]CGS 19755 and [3H]MK-801, after intrathecal injection in mice.
Topics: Animals; Dizocilpine Maleate; Injections, Spinal; Male; Mice; N-Methylaspartate; Pain Measurement; Pipecolic Acids; Reaction Time; Receptors, N-Methyl-D-Aspartate; Tissue Distribution | 1993 |
MK-801, phencyclidine (PCP), and PCP-like drugs increase burst firing in rat A10 dopamine neurons: comparison to competitive NMDA antagonists.
Topics: Action Potentials; Animals; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Illicit Drugs; Male; N-Methylaspartate; Neurons; Phencyclidine; Pipecolic Acids; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques; Tegmentum Mesencephali; Vibrissae | 1993 |
Discriminative stimulus effects of ethanol: effect of training dose on the substitution of N-methyl-D-aspartate antagonists.
Topics: Animals; Discrimination Learning; Dizocilpine Maleate; Ethanol; Generalization, Psychological; Male; Phencyclidine; Pipecolic Acids; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate | 1993 |
Sexual differences in N-methyl-D-aspartate receptor-mediated regulation of tuberoinfundibular dopaminergic neurons in the rat.
Topics: Animals; Dizocilpine Maleate; Dopamine; Female; Glycine; Hypothalamus, Middle; Male; Neurons; Pipecolic Acids; Prolactin; Rats; Receptors, N-Methyl-D-Aspartate; Sex Characteristics; Tetrazoles | 1993 |
Dissociation between cognitive and motor/motivational deficits in the delayed matching to position test: effects of scopolamine, 8-OH-DPAT and EAA antagonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cognition; Conditioning, Operant; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Motor Activity; Muscarinic Antagonists; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Scopolamine; Scopolamine Derivatives; Serotonin Receptor Agonists | 1995 |
Effects of glutamate antagonists on methamphetamine and 3,4-methylenedioxymethamphetamine-induced striatal dopamine release in vivo.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amines; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Pipecolic Acids; Rats; Rats, Sprague-Dawley | 1996 |
NMDA-but not AMPA-receptor antagonists augment scopolamine-induced spatial cognitive deficit of rats in a radial maze task.
Topics: Animals; Cognition Disorders; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Male; Maze Learning; Pipecolic Acids; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Scopolamine | 1996 |
Treatment of a chronic allodynia-like response in spinally injured rats: effects of systemically administered excitatory amino acid receptor antagonists.
Topics: Animals; Behavior, Animal; Chronic Disease; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Hyperalgesia; Ischemia; Motor Activity; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Regional Blood Flow; Spinal Cord; Spinal Cord Injuries | 1996 |
Effect of up-regulation of NMDA receptors on cerebral O2 consumption and blood flow in rat.
Topics: Animals; Brain; Cerebrovascular Circulation; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gases; Hemodynamics; Male; N-Methylaspartate; Oxygen Consumption; Pipecolic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Up-Regulation | 1996 |
Comparison of the patterns of altered cerebral glucose utilisation produced by competitive and non-competitive NMDA receptor antagonists.
Topics: Animals; Autoradiography; Behavior, Animal; Binding, Competitive; Brain; Brain Chemistry; Cerebral Cortex; Deoxyglucose; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Extrapyramidal Tracts; Glucose; Hippocampus; Isoquinolines; Limbic System; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrahydroisoquinolines | 1996 |
Pharmacological properties of acquired excitotoxicity in Chinese hamster ovary cells transfected with N-methyl-D-aspartate receptor subunits.
Topics: Animals; Calcium; Cell Survival; CHO Cells; Cricetinae; Dizocilpine Maleate; Kynurenic Acid; L-Lactate Dehydrogenase; Luciferases; Pipecolic Acids; Piperidines; Receptors, N-Methyl-D-Aspartate; Transfection | 1996 |
N-methyl-D-aspartate receptor antagonists potentiate morphine's antinociceptive effect in the rat.
Topics: Analgesics; Animals; Dextromethorphan; Dizocilpine Maleate; Drug Synergism; Male; Morphine; Nociceptors; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1996 |
The d- and l-isomers of methadone bind to the non-competitive site on the N-methyl-D-aspartate (NMDA) receptor in rat forebrain and spinal cord.
Topics: Animals; Binding Sites; Binding, Competitive; Dextromethorphan; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Isomerism; Male; Methadone; Pipecolic Acids; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synaptic Membranes | 1997 |
NMDA antagonists potentiate scopolamine-induced amnesic effect.
Topics: Amnesia; Animals; Cholinergic Antagonists; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Learning Disabilities; Male; Maze Learning; Memory, Short-Term; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Wistar; Scopolamine | 1997 |
Induction of heat-shock protein (HSP72) in the cingulate and retrosplenial cortex by drugs that antagonize the effects of excitatory amino acids.
Topics: Animals; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gyrus Cinguli; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Immunohistochemistry; Male; Pipecolic Acids; Rats; Rats, Sprague-Dawley | 1997 |
Comparative analysis of brain protection by N-methyl-D-aspartate receptor antagonists after transient focal ischemia in cats.
Topics: Amino Acids; Animals; Brain; Brain Damage, Chronic; Cats; Cerebrovascular Circulation; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Ischemic Attack, Transient; Male; Neuroprotective Agents; Pipecolic Acids; Prospective Studies; Receptors, N-Methyl-D-Aspartate | 1997 |
Homocysteine signal cascade: production of phospholipids, activation of protein kinase C, and the induction of c-fos and c-myb in smooth muscle cells.
Topics: Aorta, Abdominal; Aorta, Thoracic; Cardiovascular Diseases; Cell Division; Diglycerides; Dizocilpine Maleate; DNA; Enzyme Activation; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Genes, fos; Glutamic Acid; Homocysteine; Humans; Immunoblotting; Muscle, Smooth, Vascular; N-Methylaspartate; Oncogenes; Pipecolic Acids; Polymerase Chain Reaction; Precipitin Tests; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; RNA | 1997 |
NMDA but not AMPA receptor antagonists impair the delay-interposed radial maze performance of rats.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Maze Learning; Memory, Short-Term; Pipecolic Acids; Psychomotor Performance; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Space Perception | 1997 |
Acute effects of various GABA receptor agonists and glutamate antagonists on focal hippocampal seizures in freely moving rats elicited by low-frequency stimulation.
Topics: Animals; Anticonvulsants; Ataxia; Carbamazepine; Diazepam; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA Agonists; Hippocampus; Kynurenic Acid; Male; Muscimol; Pipecolic Acids; Quinoxalines; Rats; Rats, Wistar; Seizures | 1998 |
Focal ischemia enhances the adverse effect potential of N-methyl-D-aspartate receptor antagonists in rats.
Topics: Animals; Behavior, Animal; Binding, Competitive; Brain; Brain Ischemia; Cerebrovascular Disorders; Dizocilpine Maleate; Injections, Intraperitoneal; Male; Pipecolic Acids; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1998 |
NMDA receptor antagonists influence early development of GABAergic interneurons in the mammalian striatum.
Topics: Animals; Antimetabolites; Bromodeoxyuridine; Cell Count; Cell Survival; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Immunohistochemistry; Interneurons; Male; Neostriatum; Parvalbumins; Pipecolic Acids; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1998 |
Effects of NMDA receptor antagonists on D1 dopamine receptor-mediated changes in striatal immediate early gene expression: evidence for involvement of pharmacologically distinct NMDA receptors?
Topics: Animals; Corpus Striatum; Dextrorphan; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Genes, Immediate-Early; Male; Pipecolic Acids; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate | 1998 |
An alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) antagonist and an N-methyl-D-aspartate (NMDA) channel blocker synergistically impair spatial memory in rats.
Topics: Animals; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Male; Maze Learning; Memory; Pipecolic Acids; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1998 |
Differential effects of N-methyl-D-aspartate receptor blockade on eticlopride-induced immediate early gene expression in the medial and lateral striatum.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Gene Expression; Genes, Immediate-Early; Male; Pipecolic Acids; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Salicylamides | 1998 |
Neuroprotective interaction effects of NMDA and AMPA receptor antagonists in an in vitro model of cerebral ischemia.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Ischemia; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hypoxia; Male; Neuroprotective Agents; Pipecolic Acids; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1999 |
Effects of (+)-HA-966, CGS-19755, phencyclidine, and dizocilpine on repeated acquisition of response chains in pigeons: systemic manipulation of central glycine sites.
Topics: Animals; Central Nervous System; Columbidae; Conditioning, Operant; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Phencyclidine; Pipecolic Acids; Pyrrolidinones; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serial Learning; Serine | 1999 |
Can the "state-dependency" hypothesis explain prevention of amphetamine sensitization in rats by NMDA receptor antagonists?
Topics: Amphetamine; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Hypersensitivity; Excitatory Amino Acid Antagonists; Male; Motor Activity; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Chloride | 1999 |
Glutamate release through volume-activated channels during spreading depression.
Topics: Animals; Anion Transport Proteins; Carrier Proteins; Chelating Agents; Cortical Spreading Depression; Dizocilpine Maleate; Egtazic Acid; Excitatory Amino Acid Antagonists; Furocoumarins; Glutamic Acid; In Vitro Techniques; Nitrobenzoates; Pipecolic Acids; Rats; Rats, Sprague-Dawley | 1999 |
Regional distribution and pharmacological characteristics of [3H]N-acetyl-aspartyl-glutamate (NAAG) binding sites in rat brain.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Brain Chemistry; Carboxypeptidases; Cold Temperature; Cycloleucine; Cyclopropanes; Dipeptides; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamate Carboxypeptidase II; Glycine; Kainic Acid; Male; Nerve Tissue Proteins; Phosphoserine; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tetrazoles | 2001 |
The HIV-1 coat protein gp120 and some of its fragments potently activate native cerebral NMDA receptors mediating neuropeptide release.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Cholecystokinin; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; HIV Envelope Protein gp120; HIV-1; Indoles; Kynurenic Acid; Male; Maleimides; Neurons; Nitroarginine; Peptide Fragments; Pipecolic Acids; Piperazines; Piperidines; Potassium; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Somatostatin; Synaptic Transmission; Synaptosomes; Zinc | 2000 |
Neurotoxicity of NAAG in vivo is sensitive to NMDA antagonists and mGluR II ligands.
Topics: Animals; Cell Death; Cerebral Ventricles; Dipeptides; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Injections, Intraventricular; Ligands; Male; Neurons; Neurotoxins; Pipecolic Acids; Quinolinic Acid; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2000 |
Degree of immediate early gene induction in striatum by eticlopride determines sensitivity to N-methyl-D-aspartate receptor blockade.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Gene Expression; Genes, Immediate-Early; Male; Phosphodiesterase Inhibitors; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Salicylamides | 2000 |
Neuroprotective effects of N-methyl-D-aspartate receptor antagonist on aspartate induced neurotoxicity in the spinal cord in vivo.
Topics: Animals; Aspartic Acid; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Neurons; Neuroprotective Agents; Paraplegia; Pipecolic Acids; Rabbits; Spinal Cord | 2003 |
Cannabinoid CB1 receptor activation does not prevent the toxicity of glutamate towards embryonic chick telencephalon primary cultures.
Topics: Animals; Arachidonic Acids; Cannabinoids; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Cyclohexanols; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Endocannabinoids; Excitatory Amino Acid Antagonists; Glutamic Acid; L-Lactate Dehydrogenase; Models, Animal; Neurons; Pipecolic Acids; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Telencephalon | 2003 |
Nicotine exerts a permissive role on NMDA receptor function in hippocampal noradrenergic terminals.
Topics: Animals; Calcium; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Male; Mecamylamine; N-Methylaspartate; Nerve Endings; Nicotine; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptosomes | 2004 |
Repeated treatment with N-methyl-d-aspartate antagonists in neonatal, but not adult, rats causes long-term deficits of radial-arm maze learning.
Topics: Aging; Animals; Animals, Newborn; Brain; Brain Chemistry; Dizocilpine Maleate; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Exploratory Behavior; Female; Glutamic Acid; Learning Disabilities; Male; Maze Learning; Memory; Memory Disorders; Pipecolic Acids; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Time | 2007 |
NMDA-mediated modulation of dopamine release is modified in rat prefrontal cortex and nucleus accumbens after chronic nicotine treatment.
Topics: Analysis of Variance; Animals; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Male; N-Methylaspartate; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Pipecolic Acids; Potassium; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Synaptosomes; Time Factors; Tritium | 2009 |
Effects of N-methyl-D-aspartate receptor ligands on sensitivity to reinforcer magnitude and delayed reinforcement in a delay-discounting procedure.
Topics: Animals; Behavior, Animal; Choice Behavior; Cycloserine; Delay Discounting; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Impulsive Behavior; Ketamine; Ligands; Male; Memantine; Pipecolic Acids; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Reinforcement, Psychology | 2017 |