Page last updated: 2024-09-02

selenomethylselenocysteine and cysteine

selenomethylselenocysteine has been researched along with cysteine in 112 studies

Compound Research Comparison

Studies
(selenomethylselenocysteine)
Trials
(selenomethylselenocysteine)
Recent Studies (post-2010)
(selenomethylselenocysteine)
Studies
(cysteine)
Trials
(cysteine)
Recent Studies (post-2010) (cysteine)
202610740,13241811,457

Research

Studies (112)

TimeframeStudies, this research(%)All Research%
pre-19904 (3.57)18.7374
1990's11 (9.82)18.2507
2000's65 (58.04)29.6817
2010's29 (25.89)24.3611
2020's3 (2.68)2.80

Authors

AuthorsStudies
Ganther, HE; Ip, C2
Ganther, HE; Ip, C; Thompson, HJ2
Budnick, RM; Ganther, HE; Hayes, C; Ip, C1
Chow, CM; McConnell, WB; Nigam, SN1
Foster, SJ; Ganther, HE1
Ganther, H; Ip, C; Jiang, C; Kaeck, M; Lu, J; Thompson, H; Vadhanavikit, S1
Ganther, H; Ip, C; Lisk, DJ; Lu, J; Pei, H; Thompson, HJ1
Medina, D; Sinha, R1
Guo, X; Wu, L1
Böck, A; Neuhierl, B; Wang, Y1
Esaki, N; Oikawa, T; Soda, K1
Jaken, S; Kiley, SC; Lu, JX; Medina, D; Moraes, R; Sinha, R; Thompson, HJ1
Matthews, RG; Smith, AE; Zhou, ZS1
Ip, C; Polan, CE; Uden, PC; Welbaum, G; Whanger, PD1
Matthews, RG; Peariso, K; Penner-Hahn, JE; Smith, AE; Zhou, ZS1
Cho, DY; Chung, AS; Jung, U; Kim, T1
Block, E; Dong, Y; Ip, C; Lisk, D1
Chung, AS; Jung, U; Yoon, SO; Zheng, X1
Ganther, HE; Singh, U; Sinha, R; Unni, E1
Commandeur, JN; Rooseboom, M; Vermeulen, NP1
Ganther, H; Ip, C; Medina, D; Thompson, H1
Reid, TW; Shriver, BJ; Spallholz, JE1
Baek, WK; Cha, SD; Cho, CH; Cho, JW; Kim, SP; Kwon, TK; Park, JW; Suh, MH; Suh, SI; Yeo, JK1
Hilvert, D; Roelfes, G1
DI SOMMA, AA; JACOBS, AL; TRELEASE, SF1
SHRIFT, A; VIRUPAKSHA, TK1
Baek, WK; Choi, ES; Im, KJ; Jang, BC; Kim, SP; Kwon, TK; Park, JW; Suh, MH; Suh, SI1
AbdelSamie, M; Böck, A; Caruso, J; Chiang, CY; deSouza, M; LeDuc, DL; Malit, MF; Meija, J; Montes-Bayon, M; Neuhierl, B; Tagmount, A; Tarun, AS; Terry, N; Wu, CP1
Albrecht, C; Brunk, DG; Ellis, DR; Harris, HH; Lahner, B; Orser, C; Pickering, IJ; Salt, DE; Sors, TG; Wood, KV1
Buzin, Y; Carrasco, N; Halpert, E; Huang, Z; Tyson, E1
Palace, VP; Reid, TW; Spallholz, JE1
Cao, S; Durrani, FA; Rustum, YM1
Block, E; Boakye, HT; Glass, RS; Jacobsen, NE; Johnson, S; Kahakachchi, C; Kamiński, R; Skowrońska, A; Tyson, JF; Uden, PC1
Azrak, RG; Cao, S; Durrani, FA; Frank, C; Li, ZR; Rustum, YM; Yin, MB1
Kittrell, FS; Singh, U; Sinha, R; Unni, E1
Booker, SJ; Iwig, DF1
Heller, LI; Kochian, LV; Li, L; Lyi, SM; Rutzke, M; Welch, RM1
Azrak, RG; Cao, S; Durrani, FA; Li, X; McLeod, HL; Pendyala, L; Rustum, YM; Shannon, WD; Smith, PF; Yu, J1
Cao, S; Durrani, FA; Fakih, M; Rustum, YM1
Koul, D; Sinha, R; Unni, E; Yung, WK1
Su, M; Tian, DP; Wu, XY; Zhang, G1
Abdulah, R; Koyama, H; Miyazaki, K; Nakazawa, M1
Azrak, RG; Bhattacharya, A; Cao, S; Durrani, FA; Frank, C; Hapke, G; Li, ZR; Rustum, YM; Tóth, K; Yin, MB1
Dong, Y; Gao, AC; Ip, C; Lee, SO; Nadiminty, N; Trump, DL; Yeon Chun, J1
Kim, YH; Kwon, TK; Lee, TJ; Min, do S; Park, JW1
Burchfiel, J; Butler, JA; Forsberg, NE; Liang, YC; Ou, BR; Whanger, PD; Yeh, JY1
Azrak, RG; Foster, BA; Frank, CL; Li, F; Ling, X; Rustum, YM; Slocum, HK1
Doi, C; Suzuki, KT; Suzuki, N1
Fakra, S; Freeman, JL; Marcus, MA; Pilon-Smits, EA; Quinn, CF1
Azrak, RG; Cao, S; Combs, GF; Durrani, FA; Fakih, M; Pendyala, L; Prey, J; Rustum, YM; Smith, PF1
Fakra, S; Freeman, JL; Lindblom, SD; Marcus, MA; Pilon-Smits, EAH; Quinn, CF1
Wang, X; Xu, T; Zhang, J1
Bravo, L; Cámara, C; Cuello, S; Goya, L; Madrid, Y; Martín, MA; Mateos, R; Ramos, S1
Ohta, Y; Suzuki, KT; Suzuki, N; Tsuji, Y1
Crowell, JA; Johnson, WD; Kapetanovic, I; McCormick, DL; Morrissey, RL1
Jiao, NL; Wang, J; Zheng, J1
Elliott, RM; Fairweather-Tait, SJ; Goldson, AJ; Hurst, R1
Gangapurkar, B; Jariwalla, RJ; Nakamura, D1
Bhattacharya, A; Oven, SD; Rustum, YM; Seshadri, M; Tóth, K; Vaughan, MM1
Bhattacharya, A; Cao, S; Chintala, S; Durrani, FA; Rustum, YM; Slocum, HK; Tóth, K1
Chung, AS; Jung, JY; Kim, A; Lee, SH; Lim, JS; Son, M1
Belame, A; Burow, ME; Carrier, L; Li, Z; Rowan, BG; Salvo, VA; Thiyagarajah, A1
Mahn, AV; Ruz, M; Toledo, HM1
Baranska, A; Bryla, J; Dudziak, M; Hapka, M; Kiersztan, A; Lebiedzinska, M; Winiarska, K1
Blankenberg, S; Handy, DE; Lackner, KJ; Loscalzo, J; Lubos, E; Messow, CM; Munzel, T; Peetz, D; Schnabel, R; Sinning, CR; Wild, PS; Zeller, T1
Brummell, DA; Hunter, DA; Joyce, NI; Matich, AJ; McKenzie, MJ; Pathirana, R; Rowan, DD; Watson, LM1
Duan, J; Hu, B1
Zarbl, H; Zhang, X1
Ogra, Y; Suzuki, N; T Suzuki, K; Tsuji, Y1
Kwon, TK; Lee, JT; Lee, TJ; Park, JW1
Bonorden, MJ; Cleary, MP; Hu, H; Lee, HJ; Li, GX; Liao, JD; Lü, J; Wang, L; Zhang, Y1
Cervinka, M; Hasková, P; Králová, V; Rudolf, E; Schröterová, L; Vorácová, A1
Bhattacharya, A; Cao, S; Durrani, FA; Faber, E; Repasky, EA; Rustum, YM; Sen, A; Seshadri, M; Tóth, K1
Hirano, S; Kobayashi, Y; Konishi, S; Ohta, Y1
Mahn, AV; Ruz, MH; Toledo, HM1
Ahmad, A; Jain, VK; Kumar, BS; Kumbhare, LB; Kunwar, A; Priyadarsini, KI1
Amoako, PO; Tyson, JF; Uden, PC1
Dempsey, S; Jack, C; Miller, CH; Nisa, S; O'Toole, R1
Echigo, S; Endo, M; Rikiishi, H; Shinohara, F; Suzuki, M1
Cao, S; Chintala, S; Durrani, FA; Jensen, RL; Rustum, YM; Tóth, K; Vaughan, MM1
Li, S; Manning, E; Mathew, J; Pham, S; Ruiz, P; Salgar, SK; Vazquez-Padron, RI1
Cheng, WH; Kang, MM; Schoene, NW; Wu, M1
Fang, MZ; Zarbl, H; Zhang, X1
Ahmad, A; Kumar, BS; Kunwar, A; Priyadarsini, KI; Singh, BG1
Canene-Adams, K; Diamond, AM; Erdman, JW; Ford, NA; Lindshield, BL; Wallig, MA1
Begaye, A; Ross, S; Uthus, E; Zeng, H1
Anderson, LB; Lü, J; Wang, L; Witthuhn, B; Xu, Y; Zhang, J1
Dong, Y; Gao, L; Gao, R; Liu, X; Zhang, H; Zhao, L; Zhao, X; Zhao, Y1
Cheng, WH; Lartey, FM; Qi, Y; Schoene, NW1
García-Barrera, T; Gómez-Ariza, JL; Moreno, F1
Bennett, LE; Cappa, JJ; Fakra, SC; Freeman, JL; Lindblom, SD; Marcus, MA; Pilon-Smits, EA; Quinn, CF; Quinn, EK; Reynolds, RJ1
Cheng, WH; Combs, GF; Jackson, MI; Zeng, H1
Badmaev, V; Chen, WJ; Ho, CT; Hong, HM; Jhang, AZ; Lin, CL; Nagabhushanam, K; Pan, MH; Tsai, JH1
Aitken, JB; de Jonge, MD; Finney, LA; Harris, HH; Howard, DL; Musgrave, IF; Paterson, DJ; Vogt, S; Weekley, CM1
Cleary, MP; Liao, JD; Lü, J; Nkhata, K; Quealy, E; Wang, L; Zhang, J; Zhang, Y1
Bhattacharya, A; Hoffman, RM; Rajput, A; Rustum, YM; San Martin, ID; Seshadri, M; Turowski, SG1
Hillestrøm, PR; Kápolna, E; Larsen, EH; Mapelli, V; Olsson, L1
Bhattacharya, A1
Bernhard, EJ1
Anderson, LB; Li, G; Lü, J; Wang, L; Witthuhn, B; Xu, Y; Zhang, J1
Cuderman, P; Germ, M; Mechora, S; Stibilj, V1
Bergan, R; Coomes, M; Crowell, J; Davis, W; Dew, A; Fakih, M; Fetterly, G; French-Christy, R; Ip, C; Jovanovic, B; Marshall, JR; Perloff, M; Romano, K1
Azrak, RG; Bhattacharya, A; Cao, S; Durrani, FA; Rustum, YM; Toth, K1
Brummell, DA; Hunter, DA; Joyce, NI; McKenzie, MJ; Pathirana, R; Watson, LM; West, PJ1
Herodes, K; Leito, I; Rebane, R1
Aitken, JB; Harris, HH; Musgrave, IF; Weekley, CM1
Antoch, MP; Chernov, MV; Comas-Soberats, M; Fedtsova, N; Gleiberman, AS; Gudkov, AV; Hu, Y; Jackson, M; Kuropatwinski, KK; Rustum, YM; Spengler, ML1
Haupt, DJ; Hondal, RJ; Masterson, DS; Previs, MJ; Ste Marie, EJ; van der Vliet, A; Wehrle, RJ; Wood, NB1
Wang, G; Wu, H; Zhan, Q1
Liao, Y; Wang, F; Yang, H; Yin, X; Zhao, M; Zhou, Y1

Reviews

7 review(s) available for selenomethylselenocysteine and cysteine

ArticleYear
Vitamin B6 enzymes participating in selenium amino acid metabolism.
    BioFactors (Oxford, England), 1999, Volume: 10, Issue:2-3

    Topics: Animals; Bacteria; Carbon-Sulfur Lyases; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Lyases; Mammals; Models, Chemical; Organoselenium Compounds; Pyridoxine; Selenocysteine

1999
Chemistry and biological activity of novel selenium-containing compounds.
    Advances in experimental medicine and biology, 2001, Volume: 500

    Topics: Animals; Anticarcinogenic Agents; Cysteine; Humans; Kidney Neoplasms; Molecular Weight; Organoselenium Compounds; Prodrugs; Selenium Compounds; Selenocysteine

2001
Se-methylselenocysteine: a new compound for chemoprevention of breast cancer.
    Nutrition and cancer, 2001, Volume: 40, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Cysteine; Disease Models, Animal; Female; Humans; Mammary Neoplasms, Experimental; Organoselenium Compounds; Selenocysteine; Treatment Outcome

2001
Selenium protects against toxicity induced by anticancer drugs and augments antitumor activity: a highly selective, new, and novel approach for the treatment of solid tumors.
    Clinical colorectal cancer, 2005, Volume: 5, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cysteine; Drug Synergism; Humans; Irinotecan; Mice; Neoplasms; Organoselenium Compounds; Rats; Selenocysteine; Selenomethionine

2005
Chemical forms of selenium for cancer prevention.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2005, Volume: 19, Issue:2-3

    Topics: Anticarcinogenic Agents; Chromatography; Chromatography, High Pressure Liquid; Cysteine; Food; Glutathione Peroxidase; Humans; Iodide Peroxidase; Mass Spectrometry; Methionine Sulfoxide Reductases; Models, Chemical; Neoplasms; Organoselenium Compounds; Selenium; Selenocysteine; Selenoprotein P; Selenoprotein W; Thioredoxin-Disulfide Reductase

2005
Methylselenocysteine: a promising antiangiogenic agent for overcoming drug delivery barriers in solid malignancies for therapeutic synergy with anticancer drugs.
    Expert opinion on drug delivery, 2011, Volume: 8, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Cysteine; Drug Synergism; Humans; Neoplasms; Organoselenium Compounds; Selenocysteine

2011
Interventions that induce modifications in the tumor microenvironment.
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2011, Volume: 15, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Adhesion; Cell Hypoxia; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Cysteine; Cytotoxins; Drug Screening Assays, Antitumor; Extracellular Matrix; Genetic Therapy; Humans; Immunotherapy; Molecular Targeted Therapy; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Neoplastic Stem Cells; Neovascularization, Pathologic; Organoselenium Compounds; Radiation Tolerance; Radiotherapy; Selenocysteine; Signal Transduction; Stromal Cells; Tumor Microenvironment

2011

Trials

2 trial(s) available for selenomethylselenocysteine and cysteine

ArticleYear
Selenium supplementation improves antioxidant capacity in vitro and in vivo in patients with coronary artery disease The SElenium Therapy in Coronary Artery disease Patients (SETCAP) Study.
    American heart journal, 2008, Volume: 156, Issue:6

    Topics: Aged; Antioxidants; Coronary Artery Disease; Coronary Vessels; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; Erythrocytes; Female; Glutathione Peroxidase; Humans; In Vitro Techniques; Male; Middle Aged; Organoselenium Compounds; Prospective Studies; Selenocysteine; Selenomethionine; Sodium Selenite; Vasodilation

2008
Methyl selenocysteine: single-dose pharmacokinetics in men.
    Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:11

    Topics: Adult; Cohort Studies; Cysteine; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Male; Maximum Tolerated Dose; Organoselenium Compounds; Selenocysteine; Treatment Outcome

2011

Other Studies

103 other study(ies) available for selenomethylselenocysteine and cysteine

ArticleYear
Comparison of selenium and sulfur analogs in cancer prevention.
    Carcinogenesis, 1992, Volume: 13, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Betaine; Cystamine; Cysteamine; Cysteine; Diet; Female; Mammary Neoplasms, Experimental; Organoselenium Compounds; Rats; Rats, Inbred Strains; Selenocysteine

1992
Changes in ornithine decarboxylase activity and polyamine levels in response to eight different forms of selenium.
    Journal of inorganic biochemistry, 1991, Volume: 44, Issue:4

    Topics: Adenosylmethionine Decarboxylase; Animals; Cysteine; Enzyme Induction; Female; Liver; Methylation; Organoselenium Compounds; Ornithine Decarboxylase; Oxidation-Reduction; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Selenium; Selenium Compounds; Selenocysteine; Spermidine; Spermine; Structure-Activity Relationship

1991
Chemical form of selenium, critical metabolites, and cancer prevention.
    Cancer research, 1991, Jan-15, Volume: 51, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Arsenic; Arsenites; Cysteine; Female; Glutathione Peroxidase; Liver; Mammary Neoplasms, Experimental; Organoselenium Compounds; Oxides; Rats; Rats, Inbred Strains; Selenious Acid; Selenium; Selenocysteine

1991
Combination of blocking agents and suppressing agents in cancer prevention.
    Carcinogenesis, 1991, Volume: 12, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Allyl Compounds; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Cysteine; Drug Antagonism; Drug Synergism; Ellagic Acid; Female; Mammary Neoplasms, Experimental; Organoselenium Compounds; Quercetin; Rats; Rats, Inbred Strains; Selenium; Selenocysteine; Selenomethionine; Sulfides

1991
The incorporation of radioactivity from a mixture of selenium-75 and (methyl- 3 H)selenomethionines into selenomethylselenocysteine.
    Canadian journal of biochemistry, 1973, Volume: 51, Issue:4

    Topics: Biological Transport; Cysteine; Methionine; Methylation; Plants; Radioisotopes; Selenium; Selenocysteine; Tritium

1973
Synthesis of [75Se]trimethylselenonium iodide from [75Se]selenocystine.
    Analytical biochemistry, 1984, Volume: 137, Issue:1

    Topics: Borohydrides; Chemical Phenomena; Chemistry; Cysteine; Cystine; Hydrocarbons, Iodinated; Methods; Organometallic Compounds; Organoselenium Compounds; Radioisotopes; Selenium; Selenium Compounds; Selenocysteine

1984
Dissociation of the genotoxic and growth inhibitory effects of selenium.
    Biochemical pharmacology, 1995, Jul-17, Volume: 50, Issue:2

    Topics: Animals; Cell Death; Cell Division; Cysteine; DNA, Single-Stranded; Dose-Response Relationship, Drug; Mice; Organoselenium Compounds; Selenium; Selenium Compounds; Selenocysteine; Sodium Selenite; Tumor Cells, Cultured

1995
Effect on an aqueous extract of selenium-enriched garlic on in vitro markers and in vivo efficacy in cancer prevention.
    Carcinogenesis, 1996, Volume: 17, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Cycle; Cell Division; Cysteine; DNA Damage; DNA, Neoplasm; Female; Freeze Drying; Garlic; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Organoselenium Compounds; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Selenium; Selenocysteine; Sodium Selenite

1996
Inhibition of cdk2 kinase activity by methylselenocysteine in synchronized mouse mammary epithelial tumor cells.
    Carcinogenesis, 1997, Volume: 18, Issue:8

    Topics: Animals; CDC2-CDC28 Kinases; Cell Cycle; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cyclins; Cysteine; DNA; Epithelium; Mammary Glands, Animal; Mice; Organoselenium Compounds; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Selenocysteine; Tumor Cells, Cultured

1997
Distribution of free seleno-amino acids in plant tissue of Melilotus indica L. grown in selenium-laden soils.
    Ecotoxicology and environmental safety, 1998, Volume: 39, Issue:3

    Topics: Amino Acids; Antiviral Agents; Cysteine; Cystine; Fabaceae; Gas Chromatography-Mass Spectrometry; Organoselenium Compounds; Plants, Edible; Plants, Medicinal; Selenium; Selenocysteine; Selenomethionine; Soil; Sulfhydryl Reagents

1998
Acquisition of selenium tolerance by a selenium non-accumulating Astragalus species via selection.
    BioFactors (Oxford, England), 1999, Volume: 9, Issue:1

    Topics: Blotting, Western; Cell Division; Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; Drug Tolerance; Electrophoresis, Gel, Two-Dimensional; Enzyme Induction; Isoelectric Point; Methylation; Methyltransferases; Organoselenium Compounds; Plant Cells; Plant Proteins; Plants; Selection, Genetic; Selenium; Selenocysteine; Sodium Selenite; Time Factors

1999
Effects of methylselenocysteine on PKC activity, cdk2 phosphorylation and gadd gene expression in synchronized mouse mammary epithelial tumor cells.
    Cancer letters, 1999, Nov-15, Volume: 146, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Antigens, Differentiation; Blotting, Western; CCAAT-Enhancer-Binding Proteins; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Cysteine; DNA-Binding Proteins; Female; GADD45 Proteins; Gene Expression; Intracellular Signaling Peptides and Proteins; Isoenzymes; Mammary Neoplasms, Experimental; Mice; Organoselenium Compounds; Phosphorylation; Protein Kinase C; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Proteins; Selenocysteine; Thymidine; Transcription Factor CHOP; Transcription Factors; Tumor Cells, Cultured

1999
Selenium modulation of cell proliferation and cell cycle biomarkers in normal and premalignant cells of the rat mammary gland.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2000, Volume: 9, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Antimetabolites; Antineoplastic Agents; Biomarkers; Bromodeoxyuridine; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Chemoprevention; Coloring Agents; Cyclin D; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Cysteine; Enzyme Inhibitors; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Microtubule-Associated Proteins; Organoselenium Compounds; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Selenocysteine; Tumor Suppressor Proteins

2000
L-Selenohomocysteine: one-step synthesis from L-selenomethionine and kinetic analysis as substrate for methionine synthases.
    Bioorganic & medicinal chemistry letters, 2000, Nov-06, Volume: 10, Issue:21

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Anticarcinogenic Agents; Chromatography, High Pressure Liquid; Cysteine; Female; Humans; Kinetics; Male; Molecular Structure; Organoselenium Compounds; Oxidation-Reduction; Selenium; Selenocysteine; Selenomethionine

2000
Tumorigenesis, metabolism, speciation, bioavailability, and tissue deposition of selenium in selenium-enriched ramps (Allium tricoccum).
    Journal of agricultural and food chemistry, 2000, Volume: 48, Issue:11

    Topics: Allium; Animals; Anticarcinogenic Agents; Biological Availability; Cystathionine; Cysteine; Diet; Dipeptides; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Selenium; Selenocysteine; Tissue Distribution

2000
Characterization of the zinc sites in cobalamin-independent and cobalamin-dependent methionine synthase using zinc and selenium X-ray absorption spectroscopy.
    Biochemistry, 2001, Jan-30, Volume: 40, Issue:4

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bacterial Proteins; Binding Sites; Cysteine; Escherichia coli; Escherichia coli Proteins; Methyltransferases; Organoselenium Compounds; Selenium; Selenocysteine; Spectrum Analysis; Substrate Specificity; Vitamin B 12; X-Rays; Zinc

2001
Se-methylselenocysteine induces apoptosis through caspase activation in HL-60 cells.
    Carcinogenesis, 2001, Volume: 22, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Anticarcinogenic Agents; Apoptosis; Caspase 3; Caspases; Cysteine; DNA Damage; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; HL-60 Cells; Humans; Immunoblotting; In Situ Nick-End Labeling; Organoselenium Compounds; Poly(ADP-ribose) Polymerases; Selenocysteine; Sodium Selenite; Time Factors

2001
Characterization of the biological activity of gamma-glutamyl-Se-methylselenocysteine: a novel, naturally occurring anticancer agent from garlic.
    Cancer research, 2001, Apr-01, Volume: 61, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Cysteine; Female; Gene Expression Regulation, Neoplastic; Intestinal Absorption; Mammary Neoplasms, Experimental; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Selenium; Selenocysteine

2001
Se-methylselenocysteine induces apoptosis mediated by reactive oxygen species in HL-60 cells.
    Free radical biology & medicine, 2001, Aug-15, Volume: 31, Issue:4

    Topics: Acetylcysteine; Anticarcinogenic Agents; Antioxidants; Apoptosis; Blotting, Western; Caspases; Cell Survival; Cysteine; Cytochrome c Group; Enzyme Activation; Flow Cytometry; HeLa Cells; HL-60 Cells; Humans; Membrane Potentials; Organoselenium Compounds; Reactive Oxygen Species; Selenocysteine

2001
Se-methylselenocysteine activates caspase-3 in mouse mammary epithelial tumor cells in vitro.
    BioFactors (Oxford, England), 2001, Volume: 14, Issue:1-4

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Caspase 3; Caspases; Cell Cycle; Cysteine; DNA Fragmentation; DNA, Neoplasm; Enzyme Activation; Female; Mammary Neoplasms, Experimental; Mice; Organoselenium Compounds; Selenocysteine; Thymidine; Tumor Cells, Cultured

2001
Dimethyldiselenide and methylseleninic acid generate superoxide in an in vitro chemiluminescence assay in the presence of glutathione: implications for the anticarcinogenic activity of L-selenomethionine and L-Se-methylselenocysteine.
    Nutrition and cancer, 2001, Volume: 40, Issue:1

    Topics: Anticarcinogenic Agents; Cysteine; Glutathione; Glutathione Peroxidase; Kinetics; Luminescent Measurements; Organoselenium Compounds; Selenocysteine; Selenomethionine; Superoxide Dismutase; Superoxides

2001
Se-methylselenocysteine induces apoptosis through caspase activation and Bax cleavage mediated by calpain in SKOV-3 ovarian cancer cells.
    Cancer letters, 2002, Aug-08, Volume: 182, Issue:1

    Topics: Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Calpain; Caspases; Cysteine; Cytochrome c Group; Enzyme Activation; Female; Humans; Inhibitor of Apoptosis Proteins; Organoselenium Compounds; Ovarian Neoplasms; Poly(ADP-ribose) Polymerases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Selenocysteine; Tumor Cells, Cultured

2002
Incorporation of selenomethionine into proteins through selenohomocysteine-mediated ligation.
    Angewandte Chemie (International ed. in English), 2003, May-25, Volume: 42, Issue:20

    Topics: Cysteine; Methylation; Nuclear Magnetic Resonance, Biomolecular; Organoselenium Compounds; Peptides; Protein Conformation; Protein Denaturation; Proteins; Selenocysteine; Selenomethionine

2003
Seleno-amino acid found in Astragalus bisulcatus.
    Science (New York, N.Y.), 1960, Sep-02, Volume: 132, Issue:3427

    Topics: Amino Acids; Cysteine; Plants; Selenium; Selenocysteine

1960
Biosynthesis of Se-methyl-selenocysteine from selenite in selenium-accumulating plants.
    Biochimica et biophysica acta, 1963, May-14, Volume: 71

    Topics: Cysteine; Plants; Selenious Acid; Selenium; Selenium Compounds; Selenocysteine

1963
Induction of apoptosis by Se-MSC in U937 human leukemia cells through release of cytochrome c and activation of caspases and PKC-delta: mutual regulation between caspases and PKC-delta via a positive feedback mechanism.
    International journal of molecular medicine, 2003, Volume: 12, Issue:5

    Topics: Acetophenones; Apoptosis; Benzopyrans; Caspases; Cysteine; Cytochromes c; Enzyme Activation; Feedback, Physiological; Humans; Organoselenium Compounds; Poly(ADP-ribose) Polymerases; Protein Kinase C; Protein Kinase C-delta; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Selenocysteine; U937 Cells

2003
Overexpression of selenocysteine methyltransferase in Arabidopsis and Indian mustard increases selenium tolerance and accumulation.
    Plant physiology, 2004, Volume: 135, Issue:1

    Topics: Adaptation, Physiological; Arabidopsis; Cysteine; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Methyltransferases; Molecular Sequence Data; Mustard Plant; Organoselenium Compounds; Plants, Genetically Modified; Selenium; Selenocysteine; Volatilization

2004
Production of Se-methylselenocysteine in transgenic plants expressing selenocysteine methyltransferase.
    BMC plant biology, 2004, Jan-28, Volume: 4

    Topics: Arabidopsis; Astragalus Plant; Chromatography, High Pressure Liquid; Cysteine; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Mass Spectrometry; Methyltransferases; Organoselenium Compounds; Plant Shoots; Plants, Genetically Modified; Selenium; Selenocysteine; Sodium Selenite

2004
Selenium derivatization and crystallization of DNA and RNA oligonucleotides for X-ray crystallography using multiple anomalous dispersion.
    Nucleic acids research, 2004, Volume: 32, Issue:5

    Topics: Base Sequence; Crystallization; Crystallography, X-Ray; Cysteine; DNA; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Oligoribonucleotides; Organophosphorus Compounds; Organoselenium Compounds; RNA; Selenium; Selenocysteine; Uridine

2004
Methioninase and selenomethionine but not Se-methylselenocysteine generate methylselenol and superoxide in an in vitro chemiluminescent assay: implications for the nutritional carcinostatic activity of selenoamino acids.
    Biochemical pharmacology, 2004, Feb-01, Volume: 67, Issue:3

    Topics: Apoptosis; Carbon-Sulfur Lyases; Cells, Cultured; Cysteine; Humans; Luminescent Measurements; Organoselenium Compounds; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; Superoxides

2004
Selective modulation of the therapeutic efficacy of anticancer drugs by selenium containing compounds against human tumor xenografts.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Apr-01, Volume: 10, Issue:7

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Squamous Cell; Cell Line, Tumor; Colonic Neoplasms; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Irinotecan; Maximum Tolerated Dose; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Organoselenium Compounds; Radiation-Sensitizing Agents; Selenium; Selenocysteine; Selenomethionine; Time Factors

2004
Identification and synthesis of a novel selenium-sulfur amino acid found in selenized yeast: Rapid indirect detection NMR methods for characterizing low-level organoselenium compounds in complex matrices.
    Journal of agricultural and food chemistry, 2004, Jun-16, Volume: 52, Issue:12

    Topics: Chromatography, High Pressure Liquid; Cysteine; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Mass Spectrometry; Organoselenium Compounds; Saccharomyces cerevisiae; Selenium; Selenocysteine

2004
Enhanced 7-ethyl-10-hydroxycamptothecin (SN-38) lethality by methylselenocysteine is associated with Chk2 phosphorylation at threonine-68 and down-regulation of Cdc6 expression.
    Molecular pharmacology, 2004, Volume: 66, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Carbon-Sulfur Lyases; Caspase 3; Caspases; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Survival; Checkpoint Kinase 1; Checkpoint Kinase 2; Cysteine; DNA Fragmentation; Drug Interactions; Enzyme Activation; Gene Expression; Humans; Irinotecan; Minichromosome Maintenance Complex Component 2; Nuclear Proteins; Organoselenium Compounds; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Kinases; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae Proteins; Selenocysteine

2004
Osteopontin is a potential target gene in mouse mammary cancer chemoprevention by Se-methylselenocysteine.
    Breast cancer research : BCR, 2004, Volume: 6, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Caspase 3; Caspases; Cell Division; Cell Movement; Cysteine; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Organoselenium Compounds; Osteopontin; Reverse Transcriptase Polymerase Chain Reaction; Selenocysteine; Sialoglycoproteins; Tumor Cells, Cultured

2004
Insight into the polar reactivity of the onium chalcogen analogues of S-adenosyl-L-methionine.
    Biochemistry, 2004, Oct-26, Volume: 43, Issue:42

    Topics: Alkylating Agents; Biotransformation; Chalcogens; Cysteine; Escherichia coli; Humans; Methionine; Methionine Adenosyltransferase; Nuclear Magnetic Resonance, Biomolecular; Organoselenium Compounds; Protons; S-Adenosylmethionine; Selenocysteine; Selenomethionine; Stereoisomerism; Substrate Specificity; Sulfonium Compounds; Tellurium

2004
Molecular and biochemical characterization of the selenocysteine Se-methyltransferase gene and Se-methylselenocysteine synthesis in broccoli.
    Plant physiology, 2005, Volume: 138, Issue:1

    Topics: Amino Acid Sequence; Brassica; Cloning, Molecular; Cysteine; DNA, Complementary; Escherichia coli; Gene Library; Methyltransferases; Molecular Sequence Data; Organoselenium Compounds; Recombinant Proteins; Selenocysteine; Sequence Alignment; Sequence Homology, Amino Acid

2005
Irinotecan pharmacokinetic and pharmacogenomic alterations induced by methylselenocysteine in human head and neck xenograft tumors.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Carcinoma, Squamous Cell; Cysteine; Female; Head and Neck Neoplasms; Humans; Irinotecan; Mice; Mice, Nude; Organoselenium Compounds; Pharmacogenetics; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Selenocysteine; Transplantation, Heterologous; Tumor Cells, Cultured

2005
Se-methylselenocysteine inhibits phosphatidylinositol 3-kinase activity of mouse mammary epithelial tumor cells in vitro.
    Breast cancer research : BCR, 2005, Volume: 7, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Cell Division; Cell Line, Tumor; Cysteine; Enzyme Inhibitors; Epithelial Cells; Mammary Neoplasms, Animal; MAP Kinase Signaling System; Mice; Organoselenium Compounds; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Selenocysteine

2005
[Effects of selenium and B-27 supplements on viability and differentiation of neural stem cell in newborn rat].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2005, Volume: 39, Issue:5

    Topics: Animals; Animals, Newborn; Cell Differentiation; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Cysteine; Female; Glial Fibrillary Acidic Protein; Immunohistochemistry; Male; Neurons; Organoselenium Compounds; Rats; Rats, Wistar; Selenium; Selenocysteine; Sodium Selenite; Stem Cells; Tubulin

2005
Potentiation of irinotecan sensitivity by Se-methylselenocysteine in an in vivo tumor model is associated with downregulation of cyclooxygenase-2, inducible nitric oxide synthase, and hypoxia-inducible factor 1alpha expression, resulting in reduced angiog
    Oncogene, 2006, Apr-20, Volume: 25, Issue:17

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Carcinoma, Squamous Cell; Cyclooxygenase 2; Cysteine; Down-Regulation; Female; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Irinotecan; Mice; Mice, Nude; Neovascularization, Pathologic; Nitric Oxide Synthase Type II; Organoselenium Compounds; Selenocysteine; Transplantation, Heterologous

2006
Monomethylated selenium inhibits growth of LNCaP human prostate cancer xenograft accompanied by a decrease in the expression of androgen receptor and prostate-specific antigen (PSA).
    The Prostate, 2006, Jul-01, Volume: 66, Issue:10

    Topics: Animals; Anticarcinogenic Agents; Cell Line, Tumor; Cell Proliferation; Cysteine; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Nude; Organoselenium Compounds; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Selenium; Selenocysteine; Xenograft Model Antitumor Assays

2006
Se-methylselenocysteine enhances PMA-mediated CD11c expression via phospholipase D1 activation in U937 cells.
    Immunobiology, 2006, Volume: 211, Issue:5

    Topics: CD11c Antigen; Cell Differentiation; Cysteine; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Organoselenium Compounds; Phospholipase D; Selenocysteine; Tetradecanoylphorbol Acetate; U937 Cells; Up-Regulation

2006
Mechanism for proliferation inhibition by various selenium compounds and selenium-enriched broccoli extract in rat glial cells.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2006, Volume: 19, Issue:6

    Topics: Animals; Apoptosis; Brassica; Cell Line; Cell Proliferation; Cysteine; DNA Damage; Glutathione Peroxidase; Hydrogen Peroxide; Neuroglia; Organoselenium Compounds; Plant Extracts; Rats; Selenium Compounds; Selenocysteine; Selenomethionine

2006
The mechanism of methylselenocysteine and docetaxel synergistic activity in prostate cancer cells.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:10

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cysteine; Docetaxel; Down-Regulation; Drug Synergism; Enzyme Activation; Inhibitor of Apoptosis Proteins; Male; Mice; Microtubule-Associated Proteins; Neoplasm Proteins; Organoselenium Compounds; Prostatic Neoplasms; Selenocysteine; Survivin; Taxoids

2006
Metabolism of 76Se-methylselenocysteine compared with that of 77Se-selenomethionine and 82Se-selenite.
    Toxicology and applied pharmacology, 2006, Dec-01, Volume: 217, Issue:2

    Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Cysteine; Dietary Supplements; Isotopes; Kidney; Liver; Male; Mass Spectrometry; Organoselenium Compounds; Pancreas; Rats; Rats, Wistar; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; Selenoproteins; Sodium Selenite; Time Factors

2006
Selenium-tolerant diamondback moth disarms hyperaccumulator plant defense.
    Current biology : CB, 2006, Nov-21, Volume: 16, Issue:22

    Topics: Adaptation, Physiological; Animals; Biological Evolution; Brassicaceae; Chromatography, Liquid; Cysteine; Drug Resistance; Genetic Speciation; Mass Spectrometry; Moths; Organoselenium Compounds; Oviposition; Selenocysteine; Spectrum Analysis; Wasps

2006
Efficacy of increasing the therapeutic index of irinotecan, plasma and tissue selenium concentrations is methylselenocysteine dose dependent.
    Biochemical pharmacology, 2007, May-01, Volume: 73, Issue:9

    Topics: Administration, Oral; Animals; Bone Marrow; Camptothecin; Cysteine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Irinotecan; Kidney; Kinetics; Liver; Mice; Mice, Nude; Neoplasms; Organoselenium Compounds; Plasma; Selenium; Selenocysteine

2007
Selenium accumulation protects plants from herbivory by Orthoptera via toxicity and deterrence.
    The New phytologist, 2007, Volume: 175, Issue:3

    Topics: Animals; Astragalus Plant; Brassicaceae; Cysteine; Ecosystem; Organoselenium Compounds; Orthoptera; Plant Leaves; Selenium; Selenocysteine

2007
Elemental selenium at nano size (Nano-Se) as a potential chemopreventive agent with reduced risk of selenium toxicity: comparison with se-methylselenocysteine in mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 101, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Biological Availability; Chemical and Drug Induced Liver Injury; Cysteine; Enzymes; Glutathione Transferase; Growth; Indicators and Reagents; Lethal Dose 50; Liver; Malondialdehyde; Mice; Mice, Inbred Strains; Nanoparticles; Nutritional Physiological Phenomena; Organoselenium Compounds; Selenium; Selenocysteine; Survival Analysis

2008
Selenium methylselenocysteine protects human hepatoma HepG2 cells against oxidative stress induced by tert-butyl hydroperoxide.
    Analytical and bioanalytical chemistry, 2007, Volume: 389, Issue:7-8

    Topics: Anticarcinogenic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cysteine; Glutathione; Humans; Liver Neoplasms; Malondialdehyde; Organoselenium Compounds; Oxidative Stress; Reactive Oxygen Species; Selenocysteine; tert-Butylhydroperoxide; Time Factors

2007
Preferential organ distribution of methylselenol source Se-methylselenocysteine relative to methylseleninic acid.
    Toxicology and applied pharmacology, 2008, Feb-15, Volume: 227, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Cysteine; Male; Mass Spectrometry; Organoselenium Compounds; Rats; Reference Standards; Selenocysteine; Tissue Distribution

2008
Subchronic oral toxicity studies of Se-methylselenocysteine, an organoselenium compound for breast cancer prevention.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:3

    Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Breast Neoplasms; Cysteine; Dogs; Female; Liver; Male; Organoselenium Compounds; Rats; Selenocysteine

2008
[Effects of Se-methylselenocysteine on biological behavior of and matrix metalloproteinase-2 expression in human breast cancer MDA-MB-231 cells].
    Ai zheng = Aizheng = Chinese journal of cancer, 2008, Volume: 27, Issue:2

    Topics: Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cysteine; Female; Humans; Matrix Metalloproteinase 2; Organoselenium Compounds; RNA, Messenger; S Phase; Selenocysteine

2008
Se-methylselenocysteine alters collagen gene and protein expression in human prostate cells.
    Cancer letters, 2008, Sep-28, Volume: 269, Issue:1

    Topics: Cell Line, Tumor; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type IV; Collagen Type VI; Collagen Type VII; Cysteine; Gene Expression; Humans; Male; Organoselenium Compounds; Prostate; RNA, Messenger; Selenocysteine; Sodium Selenite

2008
Differential sensitivity of various human tumour-derived cell types to apoptosis by organic derivatives of selenium.
    The British journal of nutrition, 2009, Volume: 101, Issue:2

    Topics: Adenocarcinoma; Adolescent; Adult; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cysteine; Epithelial Cells; Female; Humans; Liver Neoplasms; Male; Melanoma; Middle Aged; Neoplasms; Neuroectodermal Tumors, Primitive, Peripheral; Organoselenium Compounds; Selenium Compounds; Selenocysteine; Selenomethionine; Skin Neoplasms

2009
Tumor vascular maturation and improved drug delivery induced by methylselenocysteine leads to therapeutic synergy with anticancer drugs.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Jun-15, Volume: 14, Issue:12

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Capillary Permeability; Carcinoma, Squamous Cell; Cysteine; Drug Delivery Systems; Drug Synergism; Female; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Neovascularization, Pathologic; Organoselenium Compounds; Selenocysteine; Xenograft Model Antitumor Assays

2008
Hypoxia-specific drug tirapazamine does not abrogate hypoxic tumor cells in combination therapy with irinotecan and methylselenocysteine in well-differentiated human head and neck squamous cell carcinoma a253 xenografts.
    Neoplasia (New York, N.Y.), 2008, Volume: 10, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Squamous Cell; Cell Differentiation; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cysteine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Forkhead Transcription Factors; Head and Neck Neoplasms; Humans; Irinotecan; Maximum Tolerated Dose; Mice; Mice, Nude; Neoplasm Transplantation; Organoselenium Compounds; Selenocysteine; Tirapazamine; Triazines; Xenograft Model Antitumor Assays

2008
Long exposure of non-cytotoxic concentrations of methylselenol suppresses the invasive potential of B16F10 melanoma.
    Oncology reports, 2008, Volume: 20, Issue:3

    Topics: Animals; Cell Adhesion; Cell Movement; Cell Survival; Cysteine; Dietary Supplements; Female; Fibronectins; Flow Cytometry; Gelatinases; Humans; Integrin alphaVbeta3; Integrins; Lung Neoplasms; Melanoma, Experimental; Methanol; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Organoselenium Compounds; Selenocysteine; Sodium Selenite; Survival Rate; Tumor Cells, Cultured; Vitronectin; Wound Healing

2008
Combination of methylselenocysteine with tamoxifen inhibits MCF-7 breast cancer xenografts in nude mice through elevated apoptosis and reduced angiogenesis.
    Breast cancer research and treatment, 2009, Volume: 118, Issue:1

    Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cell Division; Cyclin D1; Cysteine; Drug Synergism; Estradiol; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Neovascularization, Pathologic; Organoselenium Compounds; Random Allocation; Receptors, Progesterone; Selenocysteine; Specific Pathogen-Free Organisms; Tamoxifen; Xenograft Model Antitumor Assays

2009
Dietary supplementation with selenomethylselenocysteine produces a differential proteomic response.
    The Journal of nutritional biochemistry, 2009, Volume: 20, Issue:10

    Topics: Animals; Cysteine; Dietary Supplements; Electrophoresis, Gel, Two-Dimensional; Female; Male; Organoselenium Compounds; Proteomics; Rats; Rats, Wistar; Selenium; Selenocysteine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2009
Differential action of methylselenocysteine in control and alloxan-diabetic rabbits.
    Chemico-biological interactions, 2009, Jan-27, Volume: 177, Issue:2

    Topics: Albuminuria; Animals; Blood Glucose; Body Weight; Creatinine; Cysteine; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Kidney; Kidney Diseases; Liver; Male; Necrosis; Organoselenium Compounds; Oxidoreductases; Rabbits; Selenium; Selenocysteine; Urea

2009
Accumulation of an organic anticancer selenium compound in a transgenic Solanaceous species shows wider applicability of the selenocysteine methyltransferase transgene from selenium hyperaccumulators.
    Transgenic research, 2009, Volume: 18, Issue:3

    Topics: Anticarcinogenic Agents; Cysteine; Methyltransferases; Nicotiana; Organoselenium Compounds; Plant Proteins; Plants, Genetically Modified; Selenocysteine; Sulfate Adenylyltransferase; Transgenes

2009
Separation and determination of seleno amino acids using gas chromatography hyphenated with inductively coupled plasma mass spectrometry after hollow fiber liquid phase microextraction.
    Journal of mass spectrometry : JMS, 2009, Volume: 44, Issue:5

    Topics: Agaricales; Brassica; Chemical Fractionation; Chloroform; Cysteine; Ethionine; Garlic; Gas Chromatography-Mass Spectrometry; Organoselenium Compounds; Selenocysteine; Selenomethionine; Sensitivity and Specificity; Sodium Chloride; Toluene

2009
Chemopreventive doses of methylselenocysteine alter circadian rhythm in rat mammary tissue.
    Cancer prevention research (Philadelphia, Pa.), 2008, Volume: 1, Issue:2

    Topics: Animals; Breast Neoplasms; Carcinoma; Cell Cycle Proteins; Chemoprevention; Circadian Rhythm; Cysteine; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Mammary Glands, Animal; Methylnitrosourea; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Organoselenium Compounds; Period Circadian Proteins; Rats; Rats, Inbred F344; Selenium; Selenocysteine; Specific Pathogen-Free Organisms

2008
Selenium metabolism in rats with long-term ingestion of Se-methylselenocysteine using enriched stable isotopes.
    The Journal of toxicological sciences, 2009, Volume: 34, Issue:2

    Topics: Animals; Cysteine; Isotopes; Kidney; Liver; Male; Organoselenium Compounds; Rats; Rats, Wistar; Selenium; Selenocysteine; Tissue Distribution

2009
Se-methylselenocysteine sensitized TRAIL-mediated apoptosis via down-regulation of Bcl-2 expression.
    International journal of oncology, 2009, Volume: 34, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma; Caspases; Cysteine; Down-Regulation; Drug Evaluation, Preclinical; Drug Synergism; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Kidney Neoplasms; Organoselenium Compounds; Peptide Fragments; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Selenocysteine; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured

2009
Methyl-selenium compounds inhibit prostate carcinogenesis in the transgenic adenocarcinoma of mouse prostate model with survival benefit.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:5

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Proliferation; Cysteine; Enzyme-Linked Immunosorbent Assay; In Situ Nick-End Labeling; Insulin-Like Growth Factor I; Male; Mice; Mice, Transgenic; Organoselenium Compounds; Prostatic Neoplasms; Selenocysteine; Selenomethionine

2009
Antiproliferative effects of selenium compounds in colon cancer cells: comparison of different cytotoxicity assays.
    Toxicology in vitro : an international journal published in association with BIBRA, 2009, Volume: 23, Issue:7

    Topics: Anticarcinogenic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cysteine; Cytotoxins; Humans; Methionine; Organoselenium Compounds; Selenocysteine; Sodium Selenite; Toxicity Tests

2009
Inhibition of colon cancer growth by methylselenocysteine-induced angiogenic chemomodulation is influenced by histologic characteristics of the tumor.
    Clinical colorectal cancer, 2009, Volume: 8, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Cell Differentiation; Colon; Colorectal Neoplasms; Cysteine; Doxorubicin; Drug Delivery Systems; Drug Resistance, Neoplasm; Female; Humans; Hypoxia; Immunoenzyme Techniques; Magnetic Resonance Imaging; Mice; Mice, Nude; Neovascularization, Pathologic; Organoselenium Compounds; Selenocysteine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2009
Speciation analysis of selenium metabolites in urine and breath by HPLC- and GC-inductively coupled plasma-MS after administration of selenomethionine and methylselenocysteine to rats.
    Chemical research in toxicology, 2009, Volume: 22, Issue:11

    Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Cysteine; Exhalation; Gas Chromatography-Mass Spectrometry; Male; Organoselenium Compounds; Rats; Rats, Wistar; Selenium Compounds; Selenocysteine; Selenomethionine

2009
Organic and inorganic selenium compounds produce different protein patterns in the blood plasma of rats.
    Biological research, 2009, Volume: 42, Issue:2

    Topics: Animals; Blood Proteins; Cysteine; Dietary Supplements; Electrophoresis, Gel, Two-Dimensional; Male; Mass Spectrometry; Organoselenium Compounds; Rats; Rats, Wistar; Selenic Acid; Selenium; Selenium Compounds; Selenocysteine

2009
In vitro radioprotection studies of organoselenium compounds: differences between mono- and diselenides.
    Radiation and environmental biophysics, 2009, Volume: 48, Issue:4

    Topics: Animals; Cattle; Cell Line, Tumor; Cysteine; Cystine; DNA; DNA Damage; Gamma Rays; Lipid Peroxidation; Liposomes; Lymphocytes; Lymphoma; Mice; Mice, Inbred C57BL; Organoselenium Compounds; Protein Carbonylation; Radiation-Protective Agents; Selenocysteine; Selenomethionine; Serum Albumin, Bovine; Thiobarbituric Acid Reactive Substances; Thymus Neoplasms

2009
Speciation of selenium dietary supplements; formation of S-(methylseleno)cysteine and other selenium compounds.
    Analytica chimica acta, 2009, Oct-12, Volume: 652, Issue:1-2

    Topics: Chromatography, High Pressure Liquid; Cysteine; Dietary Supplements; Gas Chromatography-Mass Spectrometry; Organoselenium Compounds; Selenium Compounds; Selenocysteine; Spectrometry, Mass, Electrospray Ionization; Temperature

2009
Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Antitubercular Agents; Cysteine; Drug Evaluation, Preclinical; Mycobacterium; Mycobacterium smegmatis; Organoselenium Compounds; Selenocysteine; Small Molecule Libraries

2009
Differential apoptotic response of human cancer cells to organoselenium compounds.
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:3

    Topics: Anticarcinogenic Agents; Apoptosis; Blotting, Western; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Flow Cytometry; Humans; Neoplasms; Organoselenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite; Tumor Suppressor Protein p53

2010
Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1alpha.
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:5

    Topics: Animals; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Cysteine; Drug Delivery Systems; Female; Gene Knockdown Techniques; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Irinotecan; Mice; Mice, Nude; Organoselenium Compounds; Reactive Oxygen Species; RNA, Small Interfering; Selenocysteine; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2010
Interleukin-10 delivery via mesenchymal stem cells: a novel gene therapy approach to prevent lung ischemia-reperfusion injury.
    Human gene therapy, 2010, Volume: 21, Issue:6

    Topics: Animals; Bronchoalveolar Lavage Fluid; Caspase 3; Cysteine; Genetic Therapy; Genetic Vectors; Hematopoietic Stem Cells; Interleukin-10; Lung; Lung Transplantation; Male; Mesenchymal Stem Cells; Organoselenium Compounds; Rats; Rats, Inbred Lew; Reperfusion Injury; Selenocysteine

2010
Selenium compounds activate early barriers of tumorigenesis.
    The Journal of biological chemistry, 2010, Apr-16, Volume: 285, Issue:16

    Topics: Anticarcinogenic Agents; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cellular Senescence; Cysteine; DNA Damage; DNA Repair; DNA-Binding Proteins; Histones; Humans; Male; Neoplasms; Organoselenium Compounds; Oxidative Stress; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Selenium Compounds; Selenocysteine; Sodium Selenite; Tumor Suppressor Proteins

2010
Methylselenocysteine resets the rhythmic expression of circadian and growth-regulatory genes disrupted by nitrosomethylurea in vivo.
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:5

    Topics: Administration, Oral; Alkylating Agents; Animals; Anticarcinogenic Agents; Blotting, Western; Cell Proliferation; Circadian Rhythm; Cysteine; Diet; Female; Gene Expression; Gene Expression Regulation; Immunohistochemistry; Mammary Glands, Animal; Methylnitrosourea; Organoselenium Compounds; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Selenocysteine

2010
Anti-hemolytic and peroxyl radical scavenging activity of organoselenium compounds: an in vitro study.
    Biological trace element research, 2011, Volume: 140, Issue:2

    Topics: Cysteine; Cystine; Erythrocytes; Free Radical Scavengers; Hemolysis; Humans; Lipid Peroxidation; Organoselenium Compounds; Oxidation-Reduction; Peroxides; Selenocysteine; Selenomethionine

2011
Selenium, but not lycopene or vitamin E, decreases growth of transplantable dunning R3327-H rat prostate tumors.
    PloS one, 2010, Apr-29, Volume: 5, Issue:4

    Topics: Androgens; Animals; Carotenoids; Cell Proliferation; Cysteine; Lycopene; Male; Neoplasm Transplantation; Organoselenium Compounds; Prostatic Neoplasms; Rats; Selenium; Selenocysteine; Tumor Burden; Vitamin E

2010
The von Hippel-Lindau (VHL) tumor-suppressor gene is down-regulated by selenium deficiency in Caco-2 cells and rat colon mucosa.
    Biological trace element research, 2011, Volume: 142, Issue:2

    Topics: Animals; Caco-2 Cells; Cell Line, Tumor; Colon; Cysteine; DNA Methylation; Glutathione Peroxidase; Humans; Liver; Male; Mucous Membrane; Organoselenium Compounds; Promoter Regions, Genetic; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Selenium; Selenocysteine; Von Hippel-Lindau Tumor Suppressor Protein

2011
Proteomic profiling of potential molecular targets of methyl-selenium compounds in the transgenic adenocarcinoma of mouse prostate model.
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:8

    Topics: Adenocarcinoma; Animals; Biomarkers, Pharmacological; Biomarkers, Tumor; Cysteine; Disease Models, Animal; Male; Metabolome; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Organoselenium Compounds; Prostatic Neoplasms; Proteomics; Selenium Compounds; Selenocysteine; Selenomethionine

2010
Survivin gene silencing sensitizes prostate cancer cells to selenium growth inhibition.
    BMC cancer, 2010, Aug-10, Volume: 10

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cysteine; Down-Regulation; Drug Synergism; Gene Silencing; Humans; Immunoenzyme Techniques; Inhibitor of Apoptosis Proteins; Male; Mice; Mice, Nude; Neoplasms, Hormone-Dependent; Organoselenium Compounds; Prognosis; Prostatic Neoplasms; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selenocysteine; Survival Rate; Survivin

2010
Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells.
    The Journal of biological chemistry, 2010, Oct-22, Volume: 285, Issue:43

    Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Anticarcinogenic Agents; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; Colorectal Neoplasms; Cysteine; DNA Breaks; DNA Mismatch Repair; DNA Repair Enzymes; DNA-Binding Proteins; Drug Resistance, Neoplasm; Guanosine; Humans; Mismatch Repair Endonuclease PMS2; Morpholines; MutL Protein Homolog 1; Nuclear Proteins; Organoselenium Compounds; Piperidines; Protein Serine-Threonine Kinases; Pyrones; Reactive Oxygen Species; Selenocysteine; Sodium Selenite; Tumor Suppressor Proteins

2010
Simultaneous analysis of mercury and selenium species including chiral forms of selenomethionine in human urine and serum by HPLC column-switching coupled to ICP-MS.
    The Analyst, 2010, Volume: 135, Issue:10

    Topics: Chromatography, High Pressure Liquid; Cysteine; Cystine; Dietary Supplements; Humans; Mass Spectrometry; Mercury; Methylmercury Compounds; Organoselenium Compounds; Selenic Acid; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite; Stereoisomerism

2010
Selenium hyperaccumulation offers protection from cell disruptor herbivores.
    BMC ecology, 2010, Aug-27, Volume: 10

    Topics: Animals; Astragalus Plant; Brassicaceae; Cysteine; Food Preferences; Insecta; Organoselenium Compounds; Selenium; Selenocysteine; Tetranychidae

2010
Chemical form of selenium affects its uptake, transport, and glutathione peroxidase activity in the human intestinal Caco-2 cell model.
    Biological trace element research, 2011, Volume: 143, Issue:2

    Topics: Alanine; Caco-2 Cells; Cysteine; Enzyme Activation; Glutathione Peroxidase; Humans; Organoselenium Compounds; Selenium; Selenocysteine; Sodium Selenite

2011
Se-methylselenocysteine inhibits lipopolysaccharide-induced NF-κB activation and iNOS induction in RAW 264.7 murine macrophages.
    Molecular nutrition & food research, 2011, Volume: 55, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Cells, Cultured; Cysteine; Enzyme Induction; I-kappa B Proteins; Lipopolysaccharides; Macrophages; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; Organoselenium Compounds; Phosphorylation; RNA, Messenger; Selenocysteine

2011
Uptake, distribution, and speciation of selenoamino acids by human cancer cells: X-ray absorption and fluorescence methods.
    Biochemistry, 2011, Mar-15, Volume: 50, Issue:10

    Topics: Cell Line, Tumor; Cysteine; Humans; Microscopy, Fluorescence; Neoplasms; Organoselenium Compounds; Selenocysteine; Selenomethionine; X-Ray Absorption Spectroscopy

2011
Lobe-specific lineages of carcinogenesis in the transgenic adenocarcinoma of mouse prostate and their responses to chemopreventive selenium.
    The Prostate, 2011, Sep-15, Volume: 71, Issue:13

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Cell Lineage; Cysteine; Disease Models, Animal; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Metastasis; Organoselenium Compounds; Prostatic Neoplasms; Proteomics; Selenocysteine; Seminal Vesicles

2011
Magnetic resonance and fluorescence-protein imaging of the anti-angiogenic and anti-tumor efficacy of selenium in an orthotopic model of human colon cancer.
    Anticancer research, 2011, Volume: 31, Issue:2

    Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Cysteine; Diagnostic Imaging; Female; Green Fluorescent Proteins; Humans; Magnetic Resonance Imaging; Mice; Mice, Nude; Microvessels; Neovascularization, Pathologic; Organoselenium Compounds; Random Allocation; Selenocysteine; Xenograft Model Antitumor Assays

2011
Metabolic and bioprocess engineering for production of selenized yeast with increased content of seleno-methylselenocysteine.
    Metabolic engineering, 2011, Volume: 13, Issue:3

    Topics: Astragalus Plant; Cysteine; Genetic Engineering; Methyltransferases; Organoselenium Compounds; Plant Proteins, Dietary; Recombinant Proteins; Saccharomyces cerevisiae; Selenocysteine

2011
Mouse prostate proteomes are differentially altered by supranutritional intake of four selenium compounds.
    Nutrition and cancer, 2011, Volume: 63, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Cysteine; Gene Expression Profiling; Gene Expression Regulation; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Organoselenium Compounds; Prostate; Prostatic Neoplasms; Protein Biosynthesis; Proteomics; RNA, Messenger; Selenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite; Xenograft Model Antitumor Assays

2011
Distribution of Se and its species in Myriophyllum spicatum and Ceratophyllum demersum growing in water containing Se (VI).
    Chemosphere, 2011, Volume: 84, Issue:11

    Topics: Chlorophyll; Chlorophyll A; Chromatography, High Pressure Liquid; Cysteine; Cystine; Magnoliopsida; Mass Spectrometry; Organoselenium Compounds; Photosystem II Protein Complex; Selenic Acid; Selenium Compounds; Selenocysteine; Selenomethionine; Water

2011
Augmented therapeutic efficacy of irinotecan is associated with enhanced drug accumulation.
    Cancer letters, 2011, Dec-08, Volume: 311, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Chromatography, High Pressure Liquid; Cysteine; Drug Synergism; Female; Humans; Immunohistochemistry; Irinotecan; Mice; Mice, Nude; Neoplasms, Experimental; Organoselenium Compounds; Selenocysteine; Xenograft Model Antitumor Assays

2011
Biofortification of tomato (Solanum lycopersicum) fruit with the anticancer compound methylselenocysteine using a selenocysteine methyltransferase from a selenium hyperaccumulator.
    Journal of agricultural and food chemistry, 2011, Oct-26, Volume: 59, Issue:20

    Topics: Antineoplastic Agents; Cysteine; Food, Fortified; Fruit; Gene Expression; Methyltransferases; Organoselenium Compounds; Plants, Genetically Modified; Selenic Acid; Selenium; Selenium Compounds; Selenocysteine; Sodium Selenite; Solanum lycopersicum

2011
Analysis of selenomethylselenocysteine and selenomethionine by LC-ESI-MS/MS with diethyl ethoxymethylenemalonate derivatization.
    The Analyst, 2011, Dec-21, Volume: 136, Issue:24

    Topics: Chromatography, High Pressure Liquid; Cysteine; Malonates; Mercaptoethanol; Onions; Organoselenium Compounds; Oxidation-Reduction; Selenocysteine; Selenomethionine; Spectrometry, Mass, Electrospray Ionization

2011
Methylselenocysteine treatment leads to diselenide formation in human cancer cells: evidence from X-ray absorption spectroscopy studies.
    Biochemistry, 2012, Jan-24, Volume: 51, Issue:3

    Topics: Antineoplastic Agents; Benzene Derivatives; Cell Line, Tumor; Cysteine; Humans; Organoselenium Compounds; Selenium Compounds; Selenocysteine; X-Ray Absorption Spectroscopy

2012
Selenium is a modulator of circadian clock that protects mice from the toxicity of a chemotherapeutic drug via upregulation of the core clock protein, BMAL1.
    Oncotarget, 2011, Volume: 2, Issue:12

    Topics: Animals; ARNTL Transcription Factors; Cell Line, Tumor; Circadian Clocks; CLOCK Proteins; Cyclophosphamide; Cysteine; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Neoplasms; Organoselenium Compounds; Period Circadian Proteins; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Selenium Compounds; Selenocysteine; Transcription Factors; Transcription, Genetic; Transcriptional Activation

2011
Can Selenoenzymes Resist Electrophilic Modification? Evidence from Thioredoxin Reductase and a Mutant Containing α-Methylselenocysteine.
    Biochemistry, 2020, 09-15, Volume: 59, Issue:36

    Topics: Cysteine; Humans; Mutation; Oxidation-Reduction; Selenium Oxides; Selenocysteine; Selenoproteins; Thioredoxin-Disulfide Reductase; Thioredoxins

2020
Suppression of lipopolysaccharide-induced activation of RAW 264.7 macrophages by Se-methylseleno-l-cysteine.
    International immunopharmacology, 2020, Volume: 89, Issue:Pt A

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Cell Survival; Cysteine; Gene Expression Regulation; Lipopolysaccharides; Macrophage Activation; Mice; Molecular Structure; RAW 264.7 Cells; RNA, Messenger; Selenocysteine

2020
Optimized methyl donor and reduced precursor degradation pathway for seleno-methylselenocysteine production in Bacillus subtilis.
    Microbial cell factories, 2023, Oct-19, Volume: 22, Issue:1

    Topics: Bacillus subtilis; Cysteine; Selenium; Selenocysteine; Vitamin U

2023