selenomethylselenocysteine has been researched along with 10-hydroxycamptothecin in 1 studies
| Studies (selenomethylselenocysteine) | Trials (selenomethylselenocysteine) | Recent Studies (post-2010) (selenomethylselenocysteine) | Studies (10-hydroxycamptothecin) | Trials (10-hydroxycamptothecin) | Recent Studies (post-2010) (10-hydroxycamptothecin) |
|---|---|---|---|---|---|
| 202 | 6 | 107 | 326 | 3 | 178 |
| Protein | Taxonomy | selenomethylselenocysteine (IC50) | 10-hydroxycamptothecin (IC50) |
|---|---|---|---|
| DNA topoisomerase 1 | Homo sapiens (human) | 0.11 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Azrak, RG; Cao, S; Durrani, FA; Frank, C; Li, ZR; Rustum, YM; Yin, MB | 1 |
1 other study(ies) available for selenomethylselenocysteine and 10-hydroxycamptothecin
| Article | Year |
|---|---|
Enhanced 7-ethyl-10-hydroxycamptothecin (SN-38) lethality by methylselenocysteine is associated with Chk2 phosphorylation at threonine-68 and down-regulation of Cdc6 expression.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Carbon-Sulfur Lyases; Caspase 3; Caspases; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Survival; Checkpoint Kinase 1; Checkpoint Kinase 2; Cysteine; DNA Fragmentation; Drug Interactions; Enzyme Activation; Gene Expression; Humans; Irinotecan; Minichromosome Maintenance Complex Component 2; Nuclear Proteins; Organoselenium Compounds; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Kinases; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae Proteins; Selenocysteine | 2004 |