selenocysteine has been researched along with selenomethylselenocysteine in 196 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (2.04) | 18.7374 |
| 1990's | 11 (5.61) | 18.2507 |
| 2000's | 66 (33.67) | 29.6817 |
| 2010's | 91 (46.43) | 24.3611 |
| 2020's | 24 (12.24) | 2.80 |
| Authors | Studies |
|---|---|
| Ganther, HE; Ip, C | 2 |
| Ganther, HE; Ip, C; Thompson, HJ | 2 |
| Budnick, RM; Ganther, HE; Hayes, C; Ip, C | 1 |
| Chow, CM; McConnell, WB; Nigam, SN | 1 |
| Foster, SJ; Ganther, HE | 1 |
| Ganther, H; Ip, C; Jiang, C; Kaeck, M; Lu, J; Thompson, H; Vadhanavikit, S | 1 |
| Ganther, H; Ip, C; Lisk, DJ; Lu, J; Pei, H; Thompson, HJ | 1 |
| Medina, D; Sinha, R | 1 |
| Guo, X; Wu, L | 1 |
| Böck, A; Neuhierl, B; Wang, Y | 1 |
| Esaki, N; Oikawa, T; Soda, K | 1 |
| Jaken, S; Kiley, SC; Lu, JX; Medina, D; Moraes, R; Sinha, R; Thompson, HJ | 1 |
| Matthews, RG; Smith, AE; Zhou, ZS | 1 |
| Ip, C; Polan, CE; Uden, PC; Welbaum, G; Whanger, PD | 1 |
| Matthews, RG; Peariso, K; Penner-Hahn, JE; Smith, AE; Zhou, ZS | 1 |
| Cho, DY; Chung, AS; Jung, U; Kim, T | 1 |
| Block, E; Dong, Y; Ip, C; Lisk, D | 1 |
| Chung, AS; Jung, U; Yoon, SO; Zheng, X | 1 |
| Ganther, HE; Singh, U; Sinha, R; Unni, E | 1 |
| Commandeur, JN; Rooseboom, M; Vermeulen, NP | 1 |
| Ganther, H; Ip, C; Medina, D; Thompson, H | 1 |
| Reid, TW; Shriver, BJ; Spallholz, JE | 1 |
| Baek, WK; Cha, SD; Cho, CH; Cho, JW; Kim, SP; Kwon, TK; Park, JW; Suh, MH; Suh, SI; Yeo, JK | 1 |
| Hilvert, D; Roelfes, G | 1 |
| DI SOMMA, AA; JACOBS, AL; TRELEASE, SF | 1 |
| SHRIFT, A; VIRUPAKSHA, TK | 1 |
| Baek, WK; Choi, ES; Im, KJ; Jang, BC; Kim, SP; Kwon, TK; Park, JW; Suh, MH; Suh, SI | 1 |
| AbdelSamie, M; Böck, A; Caruso, J; Chiang, CY; deSouza, M; LeDuc, DL; Malit, MF; Meija, J; Montes-Bayon, M; Neuhierl, B; Tagmount, A; Tarun, AS; Terry, N; Wu, CP | 1 |
| Albrecht, C; Brunk, DG; Ellis, DR; Harris, HH; Lahner, B; Orser, C; Pickering, IJ; Salt, DE; Sors, TG; Wood, KV | 1 |
| Buzin, Y; Carrasco, N; Halpert, E; Huang, Z; Tyson, E | 1 |
| Palace, VP; Reid, TW; Spallholz, JE | 1 |
| Cao, S; Durrani, FA; Rustum, YM | 1 |
| Block, E; Boakye, HT; Glass, RS; Jacobsen, NE; Johnson, S; Kahakachchi, C; Kamiński, R; Skowrońska, A; Tyson, JF; Uden, PC | 1 |
| Azrak, RG; Cao, S; Durrani, FA; Frank, C; Li, ZR; Rustum, YM; Yin, MB | 1 |
| Kittrell, FS; Singh, U; Sinha, R; Unni, E | 1 |
| Booker, SJ; Iwig, DF | 1 |
| Heller, LI; Kochian, LV; Li, L; Lyi, SM; Rutzke, M; Welch, RM | 1 |
| Azrak, RG; Cao, S; Durrani, FA; Li, X; McLeod, HL; Pendyala, L; Rustum, YM; Shannon, WD; Smith, PF; Yu, J | 1 |
| Cao, S; Durrani, FA; Fakih, M; Rustum, YM | 1 |
| Koul, D; Sinha, R; Unni, E; Yung, WK | 1 |
| Su, M; Tian, DP; Wu, XY; Zhang, G | 1 |
| Abdulah, R; Koyama, H; Miyazaki, K; Nakazawa, M | 1 |
| Azrak, RG; Bhattacharya, A; Cao, S; Durrani, FA; Frank, C; Hapke, G; Li, ZR; Rustum, YM; Tóth, K; Yin, MB | 1 |
| Dong, Y; Gao, AC; Ip, C; Lee, SO; Nadiminty, N; Trump, DL; Yeon Chun, J | 1 |
| Kim, YH; Kwon, TK; Lee, TJ; Min, do S; Park, JW | 1 |
| Burchfiel, J; Butler, JA; Forsberg, NE; Liang, YC; Ou, BR; Whanger, PD; Yeh, JY | 1 |
| Azrak, RG; Foster, BA; Frank, CL; Li, F; Ling, X; Rustum, YM; Slocum, HK | 1 |
| Doi, C; Suzuki, KT; Suzuki, N | 1 |
| Fakra, S; Freeman, JL; Marcus, MA; Pilon-Smits, EA; Quinn, CF | 1 |
| Azrak, RG; Cao, S; Combs, GF; Durrani, FA; Fakih, M; Pendyala, L; Prey, J; Rustum, YM; Smith, PF | 1 |
| Fakra, S; Freeman, JL; Lindblom, SD; Marcus, MA; Pilon-Smits, EAH; Quinn, CF | 1 |
| Wang, X; Xu, T; Zhang, J | 1 |
| Bravo, L; Cámara, C; Cuello, S; Goya, L; Madrid, Y; Martín, MA; Mateos, R; Ramos, S | 1 |
| Ohta, Y; Suzuki, KT; Suzuki, N; Tsuji, Y | 1 |
| Crowell, JA; Johnson, WD; Kapetanovic, I; McCormick, DL; Morrissey, RL | 1 |
| Jiao, NL; Wang, J; Zheng, J | 1 |
| Elliott, RM; Fairweather-Tait, SJ; Goldson, AJ; Hurst, R | 1 |
| Gangapurkar, B; Jariwalla, RJ; Nakamura, D | 1 |
| Bhattacharya, A; Oven, SD; Rustum, YM; Seshadri, M; Tóth, K; Vaughan, MM | 1 |
| Bhattacharya, A; Cao, S; Chintala, S; Durrani, FA; Rustum, YM; Slocum, HK; Tóth, K | 1 |
| Chung, AS; Jung, JY; Kim, A; Lee, SH; Lim, JS; Son, M | 1 |
| Belame, A; Burow, ME; Carrier, L; Li, Z; Rowan, BG; Salvo, VA; Thiyagarajah, A | 1 |
| Mahn, AV; Ruz, M; Toledo, HM | 1 |
| Baranska, A; Bryla, J; Dudziak, M; Hapka, M; Kiersztan, A; Lebiedzinska, M; Winiarska, K | 1 |
| Blankenberg, S; Handy, DE; Lackner, KJ; Loscalzo, J; Lubos, E; Messow, CM; Munzel, T; Peetz, D; Schnabel, R; Sinning, CR; Wild, PS; Zeller, T | 1 |
| Brummell, DA; Hunter, DA; Joyce, NI; Matich, AJ; McKenzie, MJ; Pathirana, R; Rowan, DD; Watson, LM | 1 |
| Duan, J; Hu, B | 1 |
| Zarbl, H; Zhang, X | 1 |
| Ogra, Y; Suzuki, N; T Suzuki, K; Tsuji, Y | 1 |
| Kwon, TK; Lee, JT; Lee, TJ; Park, JW | 1 |
| Bonorden, MJ; Cleary, MP; Hu, H; Lee, HJ; Li, GX; Liao, JD; Lü, J; Wang, L; Zhang, Y | 1 |
| Cervinka, M; Hasková, P; Králová, V; Rudolf, E; Schröterová, L; Vorácová, A | 1 |
| Bhattacharya, A; Cao, S; Durrani, FA; Faber, E; Repasky, EA; Rustum, YM; Sen, A; Seshadri, M; Tóth, K | 1 |
| Hirano, S; Kobayashi, Y; Konishi, S; Ohta, Y | 1 |
| Mahn, AV; Ruz, MH; Toledo, HM | 1 |
| Ahmad, A; Jain, VK; Kumar, BS; Kumbhare, LB; Kunwar, A; Priyadarsini, KI | 1 |
| Amoako, PO; Tyson, JF; Uden, PC | 1 |
| Dempsey, S; Jack, C; Miller, CH; Nisa, S; O'Toole, R | 1 |
| Echigo, S; Endo, M; Rikiishi, H; Shinohara, F; Suzuki, M | 1 |
| Cao, S; Chintala, S; Durrani, FA; Jensen, RL; Rustum, YM; Tóth, K; Vaughan, MM | 1 |
| Li, S; Manning, E; Mathew, J; Pham, S; Ruiz, P; Salgar, SK; Vazquez-Padron, RI | 1 |
| Cheng, WH; Kang, MM; Schoene, NW; Wu, M | 1 |
| Fang, MZ; Zarbl, H; Zhang, X | 1 |
| Ahmad, A; Kumar, BS; Kunwar, A; Priyadarsini, KI; Singh, BG | 1 |
| Canene-Adams, K; Diamond, AM; Erdman, JW; Ford, NA; Lindshield, BL; Wallig, MA | 1 |
| Begaye, A; Ross, S; Uthus, E; Zeng, H | 1 |
| Anderson, LB; Lü, J; Wang, L; Witthuhn, B; Xu, Y; Zhang, J | 1 |
| Dong, Y; Gao, L; Gao, R; Liu, X; Zhang, H; Zhao, L; Zhao, X; Zhao, Y | 1 |
| Cheng, WH; Lartey, FM; Qi, Y; Schoene, NW | 1 |
| García-Barrera, T; Gómez-Ariza, JL; Moreno, F | 1 |
| Bennett, LE; Cappa, JJ; Fakra, SC; Freeman, JL; Lindblom, SD; Marcus, MA; Pilon-Smits, EA; Quinn, CF; Quinn, EK; Reynolds, RJ | 1 |
| Cheng, WH; Combs, GF; Jackson, MI; Zeng, H | 1 |
| Badmaev, V; Chen, WJ; Ho, CT; Hong, HM; Jhang, AZ; Lin, CL; Nagabhushanam, K; Pan, MH; Tsai, JH | 1 |
| Aitken, JB; de Jonge, MD; Finney, LA; Harris, HH; Howard, DL; Musgrave, IF; Paterson, DJ; Vogt, S; Weekley, CM | 1 |
| Cleary, MP; Liao, JD; Lü, J; Nkhata, K; Quealy, E; Wang, L; Zhang, J; Zhang, Y | 1 |
| Bhattacharya, A; Hoffman, RM; Rajput, A; Rustum, YM; San Martin, ID; Seshadri, M; Turowski, SG | 1 |
| Hillestrøm, PR; Kápolna, E; Larsen, EH; Mapelli, V; Olsson, L | 1 |
| Bhattacharya, A | 1 |
| Bernhard, EJ | 1 |
| Anderson, LB; Li, G; Lü, J; Wang, L; Witthuhn, B; Xu, Y; Zhang, J | 1 |
| Cuderman, P; Germ, M; Mechora, S; Stibilj, V | 1 |
| Bergan, R; Coomes, M; Crowell, J; Davis, W; Dew, A; Fakih, M; Fetterly, G; French-Christy, R; Ip, C; Jovanovic, B; Marshall, JR; Perloff, M; Romano, K | 1 |
| Azrak, RG; Bhattacharya, A; Cao, S; Durrani, FA; Rustum, YM; Toth, K | 1 |
| Brummell, DA; Hunter, DA; Joyce, NI; McKenzie, MJ; Pathirana, R; Watson, LM; West, PJ | 1 |
| Herodes, K; Leito, I; Rebane, R | 1 |
| Aitken, JB; Harris, HH; Musgrave, IF; Weekley, CM | 1 |
| Antoch, MP; Chernov, MV; Comas-Soberats, M; Fedtsova, N; Gleiberman, AS; Gudkov, AV; Hu, Y; Jackson, M; Kuropatwinski, KK; Rustum, YM; Spengler, ML | 1 |
| Gionfriddo, E; Naccarato, A; Sindona, G; Tagarelli, A | 1 |
| Choi, EM; Shin, HS; Yang, WJ | 1 |
| Anan, Y; Katayama, A; Ogihara, Y; Ogra, Y; Yawata, A | 1 |
| Christensen, MJ; Eggett, DL; Lephart, ED; Nakken, HL; Quiner, TE; Urie, PM | 1 |
| Boucher, KM; Cassidy, JP; Cassidy, PB; Fain, HD; Florell, SR; Gerads, R; Grossman, D; Leachman, SA; Moos, PJ; Tran, SM | 1 |
| Bujalance, M; Giráldez, I; Mellano, F; Morales, E; Ruiz-Azcona, P; Sánchez-Rodas, D | 1 |
| Giraldez, I; Mellano, F; Morales, E; Sanchez-Rodas, D | 1 |
| Barrientos, H; Mahn, A; Moenne, A; Sepúlveda, I | 1 |
| Aitken, JB; Finney, L; Harris, HH; Vogt, S; Weekley, CM; Witting, PK | 1 |
| Ávila, FW; Faquin, V; Guilherme, LR; Li, L; Ramos, SJ; Thannhauser, TW; Yang, Y | 2 |
| Davis, TZ; Hall, JO; Panter, KE; Pfister, JA; Stegelmeier, BL; Welch, KD | 1 |
| Bravo, L; Cámara, C; Cordero-Herrera, I; Cuello, S; Goya, L; Madrid, Y; Ramos, S | 1 |
| Callahan, DL; Doronila, A; Dunshea, FR; Kolev, SD; Maseko, T; Ng, K | 1 |
| Harris, HH; Weekley, CM | 1 |
| Hladun, KR; Kaftanoglu, O; Parker, DR; Tran, KD; Trumble, JT | 1 |
| Chantiratikul, A; Chantiratikul, P; Jitmanee, K; Maneetong, S; Sittipout, R; Thosaikham, W | 1 |
| Dernovics, M; García Reyes, JF; Kosáry, J; Németh, A | 1 |
| Davis, TZ; Green, BT; Hall, JO; Stegelmeier, BL; Welch, KD | 1 |
| Cao, S; Durrani, FA; Rustum, YM; Tóth, K | 1 |
| Bulska, E; Kurek, E; Michalska-Kacymirow, M; Smolis, A; Wierzbicka, M | 1 |
| Cerutti, S; Pacheco, P; Raba, J; Silva, MF; Torres, S | 1 |
| Bliss, TA; Brunson, SE; Cardon, BR; Christensen, MJ; Hancock, CR; Hardman, JM; Hart, CM; Hepworth, SD; Stallings, MT; Swiss, MD | 1 |
| Bothwell, IR; Luo, M | 1 |
| Chan, HM; Huang, SS; Hung, SS | 1 |
| Deng, Z; Li, H; Yao, Z; Zhang, X; Zhang, Y | 1 |
| Cámara, C; Frías, J; Madrid, Y; Martínez-Villaluenga, C; Peñas, E; Pérez-Corona, T; Porres, JM; Sánchez-Martínez, M; Urbano, G | 1 |
| Liu, Q; Ni, J; Wang, C; Zeng, Z; Zhang, R | 1 |
| Jia, X; Yang, H | 1 |
| Blanquet, S; Dauplais, M; Lazard, M; Plateau, P | 1 |
| Dong, Y; Guo, Y; Liang, Z; Liu, X; Liu, Y; Lu, L; Sun, Y; Tian, Y; Zhang, H; Zhao, X | 1 |
| Badmaev, V; Ho, CT; Kuo, FL; Lai, CS; Pan, MH; Tsai, ML; Tung, YC | 1 |
| Han, F; Huang, Z; Liu, Y; Lu, J; Sun, L; Wang, Q; Yang, Y; Zhang, H | 1 |
| Guo, HH; Huang, G; Li, JC; Shen, JN; Xu, MH; Yong, BC | 1 |
| Boring, D; Canady, K; Cobb, J; Deardorff, P; Larson, J; White, JM | 1 |
| Chen, PC; Guo, CH; Hsia, S; Hsieh, FC; Shih, MY | 1 |
| Badmaev, V; Ho, CT; Lo, CY; Pan, MH; Tsai, ML; Wang, FZ; Wang, YJ; Wu, JC | 1 |
| Kaňa, A; Mestek, O; Najmanová, J; Praus, L; Šindelářová, K; Száková, J; Tlustoš, P; Tremlová, J | 1 |
| Fang, M; Guo, WR; Kang, HG; Park, Y; Zarbl, H | 1 |
| Gil, R; Pacheco, P; Silva, MF; Torres, S | 1 |
| Guo, M; Li, C; Li, W; Liu, Y; Mu, W; Qiu, C | 1 |
| Gao, L; Han, F; Huang, Z; Liu, Y; Lu, J; Sun, L; Wang, Q | 1 |
| Bornhorst, J; Kuehnelt, D; Marschall, TA; Schwerdtle, T | 1 |
| Caruso, J; Falconer, TM; Hanley, T; Kassa, Z; Kubachka, KM; Landero, J; Mantha, M; Oliveira, A; Wilson, RA | 1 |
| Casini, G; Cestari, L; Latrofa, F; Leo, M; Marcocci, C; Marinò, M; Nardi, M; Rotondo Dottore, G; Sellari-Franceschini, S; Vitti, P | 1 |
| Bergan, R; Burk, RF; Davis, W; George, S; Hill, KE; Marshall, JR; Payne Ondracek, R; Perloff, M; Pili, R | 1 |
| Ertani, A; Parrasia, S; Schiavon, M; Vecchia, FD | 1 |
| Dawidowski, M; Górska, S; Grosicka-Maciag, E; Klimaszewska, M; Kurpios-Piec, D; Orzechowska, E; Podsadni, P; Rahden-Staroń, I; Szczepanska, A; Turło, J | 1 |
| He, Z; Lin, Z; Liu, Y; Lu, X; Yin, X; Yuan, L; Zhu, Y | 1 |
| Du, X; Liu, Q; Ni, J; Qu, X; Wang, B; Xie, Y; Zhang, Y; Zheng, L | 1 |
| Aschner, M; Bornhorst, J; Jensen, KB; Kroepfl, N; Kuehnelt, D; Marschall, TA; Rohn, I; Schwerdtle, T; Tuck, S | 1 |
| Ogra, Y; Suzuki, N; Takahashi, K | 2 |
| Bird, S; Evans, SO; Goodman, HJB; Jacobson, GM; Jameson, MB | 1 |
| Gobec, S; Jukič, M; Kotar, A; Mårtensson, LG; Mlinarič-Raščan, I; Plavec, J; Šmid, A; Urbančič, D | 1 |
| Bhattacharya, A; Chintala, S; Durrani, FA; Rustum, YM | 1 |
| Cai, Y; Dai, Z; Liang, L; Mao, Y; Pan, L; Qi, R; Su, Y; Wang, J | 1 |
| Aschner, M; Bornhorst, J; Kipp, A; Kuehnelt, D; Raschke, S; Rohn, I; Schwerdtle, T; Tuck, S | 1 |
| Fan, H; Hu, L; Huang, R; Liu, W; Shen, F; Wan, J; Wang, X; Wu, D | 1 |
| Bornhorst, J; Kroepfl, N; Kuehnelt, D; Rohn, I; Schwerdtle, T | 1 |
| Byrne, HJ; Frias, JM; Khalid, M; Ryan, SM; Vozza, G | 1 |
| Hondal, RJ; Masterson, DS; Ste Marie, EJ; Wehrle, RJ | 1 |
| Guo, Y; Hu, T; Hui, G; Li, H; Li, L; Wei, X; Wu, W; Zhang, J | 1 |
| Guo, X; Han, Y; Li, Y; Tang, C; Zhan, T; Zhang, J; Zhang, K; Zhao, Q | 1 |
| Choi, EM; Kim, D; Ku, B | 1 |
| Abohamza, E; Berry, T; Moustafa, AA | 1 |
| Brown, GK; Casey, LW; Echevarria, G; Erskine, PD; Harris, HH; Harvey, MA; Pilon-Smits, EAH; van der Ent, A | 1 |
| Cerutti, S; D'Amato, R; López, R; Maratta, A; Pacheco, P; Proetti, P; Regni, L; Trabalza-Marinucci, M | 1 |
| Guo, Y; Hu, T; Hui, G; Li, H | 1 |
| Björnstedt, M; Kiss, A; Kontsek, E; Lendvai, G; Schaff, Z; Selvam, A; Szakos, A; Szekerczés, T | 1 |
| Haupt, DJ; Hondal, RJ; Masterson, DS; Previs, MJ; Ste Marie, EJ; van der Vliet, A; Wehrle, RJ; Wood, NB | 1 |
| Wang, G; Wu, H; Zhan, Q | 1 |
| Li, M; Wang, W; Xia, J; Xia, X | 1 |
| Du, X; Iqbal, J; Li, X; Liu, Q; Liu, X; Shen, L; Shi, Q; Xie, Y; Zhang, H; Zhao, Y | 1 |
| Guo, D; Huang, J; Ji, X; Li, J; Liu, C; Ma, J; Song, H; Sun, J; Zhang, J; Zhou, Y | 1 |
| Ding, J; Fan, B; Huang, C; Li, J; Li, Y; Qi, C; Zhang, J; Zhang, Y | 1 |
| Li, J; Qin, L; Wang, J; Zhang, J; Zhong, Y | 1 |
| de Queiroz, AAA; Gonçalves Correa, ND; Silva, FD; Soares, CRJ; Vieira, DP | 1 |
| Hondal, RJ; Ste Marie, EJ | 1 |
| Goltyaev, MV; Mal'tseva, VN; Turovsky, EA; Varlamova, EG | 1 |
| Cheng, Q; Du, Q; Li, M; Liu, J; Shao, Y; Wang, W; Yang, Y; Zhou, X | 1 |
| Kang, X; Li, J; Li, Q; Ma, J; Mo, F; Si, P; Wang, M; Wang, Y; Yang, X; Zhang, J; Zhang, P; Zheng, S | 1 |
| Banjare, N; Behera, C; Gupta, PN; Kumar, A; Kumar, R; Malik, SB; Mondhe, DM; Sandha, KK; Tabassum, M | 1 |
| Bosland, MC; Deng, Y; Lü, J; Schlicht, MJ | 1 |
| Liao, Y; Ma, T; Wang, F; Yang, H; Yin, X; Zhou, Y | 1 |
| Liao, Y; Wang, F; Yang, H; Yin, X; Zhao, M; Zhou, Y | 1 |
| Cassidy, PB; Li, L; Roberts, JC; Short, MD; Xie, Y | 1 |
12 review(s) available for selenocysteine and selenomethylselenocysteine
| Article | Year |
|---|---|
Vitamin B6 enzymes participating in selenium amino acid metabolism.
Topics: Animals; Bacteria; Carbon-Sulfur Lyases; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Lyases; Mammals; Models, Chemical; Organoselenium Compounds; Pyridoxine; Selenocysteine | 1999 |
Chemistry and biological activity of novel selenium-containing compounds.
Topics: Animals; Anticarcinogenic Agents; Cysteine; Humans; Kidney Neoplasms; Molecular Weight; Organoselenium Compounds; Prodrugs; Selenium Compounds; Selenocysteine | 2001 |
Se-methylselenocysteine: a new compound for chemoprevention of breast cancer.
Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Cysteine; Disease Models, Animal; Female; Humans; Mammary Neoplasms, Experimental; Organoselenium Compounds; Selenocysteine; Treatment Outcome | 2001 |
Selenium protects against toxicity induced by anticancer drugs and augments antitumor activity: a highly selective, new, and novel approach for the treatment of solid tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cysteine; Drug Synergism; Humans; Irinotecan; Mice; Neoplasms; Organoselenium Compounds; Rats; Selenocysteine; Selenomethionine | 2005 |
Chemical forms of selenium for cancer prevention.
Topics: Anticarcinogenic Agents; Chromatography; Chromatography, High Pressure Liquid; Cysteine; Food; Glutathione Peroxidase; Humans; Iodide Peroxidase; Mass Spectrometry; Methionine Sulfoxide Reductases; Models, Chemical; Neoplasms; Organoselenium Compounds; Selenium; Selenocysteine; Selenoprotein P; Selenoprotein W; Thioredoxin-Disulfide Reductase | 2005 |
Methylselenocysteine: a promising antiangiogenic agent for overcoming drug delivery barriers in solid malignancies for therapeutic synergy with anticancer drugs.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Cysteine; Drug Synergism; Humans; Neoplasms; Organoselenium Compounds; Selenocysteine | 2011 |
Interventions that induce modifications in the tumor microenvironment.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Adhesion; Cell Hypoxia; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Cysteine; Cytotoxins; Drug Screening Assays, Antitumor; Extracellular Matrix; Genetic Therapy; Humans; Immunotherapy; Molecular Targeted Therapy; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Neoplastic Stem Cells; Neovascularization, Pathologic; Organoselenium Compounds; Radiation Tolerance; Radiotherapy; Selenocysteine; Signal Transduction; Stromal Cells; Tumor Microenvironment | 2011 |
Selenium metabolism in cancer cells: the combined application of XAS and XFM techniques to the problem of selenium speciation in biological systems.
Topics: Animals; Copper; Fluorescence; Humans; Microscopy, Fluorescence; Neoplasms; Organoselenium Compounds; Selenium; Selenocysteine; Selenomethionine; Sodium Selenite; X-Ray Absorption Spectroscopy | 2013 |
Which form is that? The importance of selenium speciation and metabolism in the prevention and treatment of disease.
Topics: Clinical Trials as Topic; Cystine; Dietary Supplements; Histone Deacetylase Inhibitors; Humans; Neoplasms; Organoselenium Compounds; Reactive Oxygen Species; Selenium Compounds; Selenocysteine; Selenomethionine; Selenoproteins; Sulfhydryl Compounds | 2013 |
Selenium accumulation and metabolism in algae.
Topics: Animals; Chlorophyta; Ecosystem; Environmental Monitoring; Humans; Seaweed; Selenic Acid; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; Water Pollutants, Chemical | 2017 |
A disease-modifying treatment for Alzheimer's disease: focus on the trans-sulfuration pathway.
Topics: Alzheimer Disease; Animals; Homocysteine; Humans; Molybdenum; Neuroprotective Agents; Selenocysteine | 2020 |
Immunomodulatory and Anti-Inflammatory Properties of Selenium-Containing Agents: Their Role in the Regulation of Defense Mechanisms against COVID-19.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; COVID-19 Drug Treatment; Humans; Immune System; Immunomodulating Agents; Organoselenium Compounds; Selenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite | 2022 |
6 trial(s) available for selenocysteine and selenomethylselenocysteine
| Article | Year |
|---|---|
Selenium supplementation improves antioxidant capacity in vitro and in vivo in patients with coronary artery disease The SElenium Therapy in Coronary Artery disease Patients (SETCAP) Study.
Topics: Aged; Antioxidants; Coronary Artery Disease; Coronary Vessels; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; Erythrocytes; Female; Glutathione Peroxidase; Humans; In Vitro Techniques; Male; Middle Aged; Organoselenium Compounds; Prospective Studies; Selenocysteine; Selenomethionine; Sodium Selenite; Vasodilation | 2008 |
Methyl selenocysteine: single-dose pharmacokinetics in men.
Topics: Adult; Cohort Studies; Cysteine; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Male; Maximum Tolerated Dose; Organoselenium Compounds; Selenocysteine; Treatment Outcome | 2011 |
Comparative oral dose toxicokinetics of selenium compounds commonly found in selenium accumulator plants.
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Kinetics; Selenic Acid; Selenocysteine; Sheep, Domestic | 2013 |
Selenomethionine and methyl selenocysteine: multiple-dose pharmacokinetics in selenium-replete men.
Topics: Adult; Aged; Case-Control Studies; Chemoprevention; Dietary Supplements; Drug Monitoring; Humans; Male; Middle Aged; Neoplasms; Selenocysteine; Selenomethionine; Time Factors | 2017 |
Comparative Safety and Pharmacokinetic Evaluation of Three Oral Selenium Compounds in Cancer Patients.
Topics: Aged; Aged, 80 and over; DNA Damage; Double-Blind Method; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Selenium Compounds; Selenocysteine; Selenomethionine | 2019 |
Effect of Dietary Methylseleninic Acid and Se-Methylselenocysteine on Carcinogen-Induced, Androgen-Promoted Prostate Carcinogenesis in Rats.
Topics: Androgens; Animals; Antioxidants; Carcinogenesis; Carcinogens; Diet; Disease Models, Animal; Humans; Male; Mice; Organoselenium Compounds; Prostate; Prostatic Neoplasms; Rats; Selenium; Selenocysteine; Selenomethionine | 2022 |
178 other study(ies) available for selenocysteine and selenomethylselenocysteine
| Article | Year |
|---|---|
Comparison of selenium and sulfur analogs in cancer prevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Betaine; Cystamine; Cysteamine; Cysteine; Diet; Female; Mammary Neoplasms, Experimental; Organoselenium Compounds; Rats; Rats, Inbred Strains; Selenocysteine | 1992 |
Changes in ornithine decarboxylase activity and polyamine levels in response to eight different forms of selenium.
Topics: Adenosylmethionine Decarboxylase; Animals; Cysteine; Enzyme Induction; Female; Liver; Methylation; Organoselenium Compounds; Ornithine Decarboxylase; Oxidation-Reduction; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Selenium; Selenium Compounds; Selenocysteine; Spermidine; Spermine; Structure-Activity Relationship | 1991 |
Chemical form of selenium, critical metabolites, and cancer prevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Arsenic; Arsenites; Cysteine; Female; Glutathione Peroxidase; Liver; Mammary Neoplasms, Experimental; Organoselenium Compounds; Oxides; Rats; Rats, Inbred Strains; Selenious Acid; Selenium; Selenocysteine | 1991 |
Combination of blocking agents and suppressing agents in cancer prevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Allyl Compounds; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Cysteine; Drug Antagonism; Drug Synergism; Ellagic Acid; Female; Mammary Neoplasms, Experimental; Organoselenium Compounds; Quercetin; Rats; Rats, Inbred Strains; Selenium; Selenocysteine; Selenomethionine; Sulfides | 1991 |
The incorporation of radioactivity from a mixture of selenium-75 and (methyl- 3 H)selenomethionines into selenomethylselenocysteine.
Topics: Biological Transport; Cysteine; Methionine; Methylation; Plants; Radioisotopes; Selenium; Selenocysteine; Tritium | 1973 |
Synthesis of [75Se]trimethylselenonium iodide from [75Se]selenocystine.
Topics: Borohydrides; Chemical Phenomena; Chemistry; Cysteine; Cystine; Hydrocarbons, Iodinated; Methods; Organometallic Compounds; Organoselenium Compounds; Radioisotopes; Selenium; Selenium Compounds; Selenocysteine | 1984 |
Dissociation of the genotoxic and growth inhibitory effects of selenium.
Topics: Animals; Cell Death; Cell Division; Cysteine; DNA, Single-Stranded; Dose-Response Relationship, Drug; Mice; Organoselenium Compounds; Selenium; Selenium Compounds; Selenocysteine; Sodium Selenite; Tumor Cells, Cultured | 1995 |
Effect on an aqueous extract of selenium-enriched garlic on in vitro markers and in vivo efficacy in cancer prevention.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Cycle; Cell Division; Cysteine; DNA Damage; DNA, Neoplasm; Female; Freeze Drying; Garlic; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Organoselenium Compounds; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Selenium; Selenocysteine; Sodium Selenite | 1996 |
Inhibition of cdk2 kinase activity by methylselenocysteine in synchronized mouse mammary epithelial tumor cells.
Topics: Animals; CDC2-CDC28 Kinases; Cell Cycle; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cyclins; Cysteine; DNA; Epithelium; Mammary Glands, Animal; Mice; Organoselenium Compounds; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Selenocysteine; Tumor Cells, Cultured | 1997 |
Distribution of free seleno-amino acids in plant tissue of Melilotus indica L. grown in selenium-laden soils.
Topics: Amino Acids; Antiviral Agents; Cysteine; Cystine; Fabaceae; Gas Chromatography-Mass Spectrometry; Organoselenium Compounds; Plants, Edible; Plants, Medicinal; Selenium; Selenocysteine; Selenomethionine; Soil; Sulfhydryl Reagents | 1998 |
Acquisition of selenium tolerance by a selenium non-accumulating Astragalus species via selection.
Topics: Blotting, Western; Cell Division; Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; Drug Tolerance; Electrophoresis, Gel, Two-Dimensional; Enzyme Induction; Isoelectric Point; Methylation; Methyltransferases; Organoselenium Compounds; Plant Cells; Plant Proteins; Plants; Selection, Genetic; Selenium; Selenocysteine; Sodium Selenite; Time Factors | 1999 |
Effects of methylselenocysteine on PKC activity, cdk2 phosphorylation and gadd gene expression in synchronized mouse mammary epithelial tumor cells.
Topics: Animals; Anticarcinogenic Agents; Antigens, Differentiation; Blotting, Western; CCAAT-Enhancer-Binding Proteins; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Cysteine; DNA-Binding Proteins; Female; GADD45 Proteins; Gene Expression; Intracellular Signaling Peptides and Proteins; Isoenzymes; Mammary Neoplasms, Experimental; Mice; Organoselenium Compounds; Phosphorylation; Protein Kinase C; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Proteins; Selenocysteine; Thymidine; Transcription Factor CHOP; Transcription Factors; Tumor Cells, Cultured | 1999 |
Selenium modulation of cell proliferation and cell cycle biomarkers in normal and premalignant cells of the rat mammary gland.
Topics: Animals; Anticarcinogenic Agents; Antimetabolites; Antineoplastic Agents; Biomarkers; Bromodeoxyuridine; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Chemoprevention; Coloring Agents; Cyclin D; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Cysteine; Enzyme Inhibitors; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Microtubule-Associated Proteins; Organoselenium Compounds; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Selenocysteine; Tumor Suppressor Proteins | 2000 |
L-Selenohomocysteine: one-step synthesis from L-selenomethionine and kinetic analysis as substrate for methionine synthases.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Anticarcinogenic Agents; Chromatography, High Pressure Liquid; Cysteine; Female; Humans; Kinetics; Male; Molecular Structure; Organoselenium Compounds; Oxidation-Reduction; Selenium; Selenocysteine; Selenomethionine | 2000 |
Tumorigenesis, metabolism, speciation, bioavailability, and tissue deposition of selenium in selenium-enriched ramps (Allium tricoccum).
Topics: Allium; Animals; Anticarcinogenic Agents; Biological Availability; Cystathionine; Cysteine; Diet; Dipeptides; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Selenium; Selenocysteine; Tissue Distribution | 2000 |
Characterization of the zinc sites in cobalamin-independent and cobalamin-dependent methionine synthase using zinc and selenium X-ray absorption spectroscopy.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bacterial Proteins; Binding Sites; Cysteine; Escherichia coli; Escherichia coli Proteins; Methyltransferases; Organoselenium Compounds; Selenium; Selenocysteine; Spectrum Analysis; Substrate Specificity; Vitamin B 12; X-Rays; Zinc | 2001 |
Se-methylselenocysteine induces apoptosis through caspase activation in HL-60 cells.
Topics: Amino Acid Chloromethyl Ketones; Anticarcinogenic Agents; Apoptosis; Caspase 3; Caspases; Cysteine; DNA Damage; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; HL-60 Cells; Humans; Immunoblotting; In Situ Nick-End Labeling; Organoselenium Compounds; Poly(ADP-ribose) Polymerases; Selenocysteine; Sodium Selenite; Time Factors | 2001 |
Characterization of the biological activity of gamma-glutamyl-Se-methylselenocysteine: a novel, naturally occurring anticancer agent from garlic.
Topics: Animals; Anticarcinogenic Agents; Cysteine; Female; Gene Expression Regulation, Neoplastic; Intestinal Absorption; Mammary Neoplasms, Experimental; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Selenium; Selenocysteine | 2001 |
Se-methylselenocysteine induces apoptosis mediated by reactive oxygen species in HL-60 cells.
Topics: Acetylcysteine; Anticarcinogenic Agents; Antioxidants; Apoptosis; Blotting, Western; Caspases; Cell Survival; Cysteine; Cytochrome c Group; Enzyme Activation; Flow Cytometry; HeLa Cells; HL-60 Cells; Humans; Membrane Potentials; Organoselenium Compounds; Reactive Oxygen Species; Selenocysteine | 2001 |
Se-methylselenocysteine activates caspase-3 in mouse mammary epithelial tumor cells in vitro.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Caspase 3; Caspases; Cell Cycle; Cysteine; DNA Fragmentation; DNA, Neoplasm; Enzyme Activation; Female; Mammary Neoplasms, Experimental; Mice; Organoselenium Compounds; Selenocysteine; Thymidine; Tumor Cells, Cultured | 2001 |
Dimethyldiselenide and methylseleninic acid generate superoxide in an in vitro chemiluminescence assay in the presence of glutathione: implications for the anticarcinogenic activity of L-selenomethionine and L-Se-methylselenocysteine.
Topics: Anticarcinogenic Agents; Cysteine; Glutathione; Glutathione Peroxidase; Kinetics; Luminescent Measurements; Organoselenium Compounds; Selenocysteine; Selenomethionine; Superoxide Dismutase; Superoxides | 2001 |
Se-methylselenocysteine induces apoptosis through caspase activation and Bax cleavage mediated by calpain in SKOV-3 ovarian cancer cells.
Topics: Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Calpain; Caspases; Cysteine; Cytochrome c Group; Enzyme Activation; Female; Humans; Inhibitor of Apoptosis Proteins; Organoselenium Compounds; Ovarian Neoplasms; Poly(ADP-ribose) Polymerases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Selenocysteine; Tumor Cells, Cultured | 2002 |
Incorporation of selenomethionine into proteins through selenohomocysteine-mediated ligation.
Topics: Cysteine; Methylation; Nuclear Magnetic Resonance, Biomolecular; Organoselenium Compounds; Peptides; Protein Conformation; Protein Denaturation; Proteins; Selenocysteine; Selenomethionine | 2003 |
Seleno-amino acid found in Astragalus bisulcatus.
Topics: Amino Acids; Cysteine; Plants; Selenium; Selenocysteine | 1960 |
Biosynthesis of Se-methyl-selenocysteine from selenite in selenium-accumulating plants.
Topics: Cysteine; Plants; Selenious Acid; Selenium; Selenium Compounds; Selenocysteine | 1963 |
Induction of apoptosis by Se-MSC in U937 human leukemia cells through release of cytochrome c and activation of caspases and PKC-delta: mutual regulation between caspases and PKC-delta via a positive feedback mechanism.
Topics: Acetophenones; Apoptosis; Benzopyrans; Caspases; Cysteine; Cytochromes c; Enzyme Activation; Feedback, Physiological; Humans; Organoselenium Compounds; Poly(ADP-ribose) Polymerases; Protein Kinase C; Protein Kinase C-delta; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Selenocysteine; U937 Cells | 2003 |
Overexpression of selenocysteine methyltransferase in Arabidopsis and Indian mustard increases selenium tolerance and accumulation.
Topics: Adaptation, Physiological; Arabidopsis; Cysteine; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Methyltransferases; Molecular Sequence Data; Mustard Plant; Organoselenium Compounds; Plants, Genetically Modified; Selenium; Selenocysteine; Volatilization | 2004 |
Production of Se-methylselenocysteine in transgenic plants expressing selenocysteine methyltransferase.
Topics: Arabidopsis; Astragalus Plant; Chromatography, High Pressure Liquid; Cysteine; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Mass Spectrometry; Methyltransferases; Organoselenium Compounds; Plant Shoots; Plants, Genetically Modified; Selenium; Selenocysteine; Sodium Selenite | 2004 |
Selenium derivatization and crystallization of DNA and RNA oligonucleotides for X-ray crystallography using multiple anomalous dispersion.
Topics: Base Sequence; Crystallization; Crystallography, X-Ray; Cysteine; DNA; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Oligoribonucleotides; Organophosphorus Compounds; Organoselenium Compounds; RNA; Selenium; Selenocysteine; Uridine | 2004 |
Methioninase and selenomethionine but not Se-methylselenocysteine generate methylselenol and superoxide in an in vitro chemiluminescent assay: implications for the nutritional carcinostatic activity of selenoamino acids.
Topics: Apoptosis; Carbon-Sulfur Lyases; Cells, Cultured; Cysteine; Humans; Luminescent Measurements; Organoselenium Compounds; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; Superoxides | 2004 |
Selective modulation of the therapeutic efficacy of anticancer drugs by selenium containing compounds against human tumor xenografts.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Squamous Cell; Cell Line, Tumor; Colonic Neoplasms; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Irinotecan; Maximum Tolerated Dose; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Organoselenium Compounds; Radiation-Sensitizing Agents; Selenium; Selenocysteine; Selenomethionine; Time Factors | 2004 |
Identification and synthesis of a novel selenium-sulfur amino acid found in selenized yeast: Rapid indirect detection NMR methods for characterizing low-level organoselenium compounds in complex matrices.
Topics: Chromatography, High Pressure Liquid; Cysteine; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Mass Spectrometry; Organoselenium Compounds; Saccharomyces cerevisiae; Selenium; Selenocysteine | 2004 |
Enhanced 7-ethyl-10-hydroxycamptothecin (SN-38) lethality by methylselenocysteine is associated with Chk2 phosphorylation at threonine-68 and down-regulation of Cdc6 expression.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Carbon-Sulfur Lyases; Caspase 3; Caspases; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Survival; Checkpoint Kinase 1; Checkpoint Kinase 2; Cysteine; DNA Fragmentation; Drug Interactions; Enzyme Activation; Gene Expression; Humans; Irinotecan; Minichromosome Maintenance Complex Component 2; Nuclear Proteins; Organoselenium Compounds; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Kinases; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae Proteins; Selenocysteine | 2004 |
Osteopontin is a potential target gene in mouse mammary cancer chemoprevention by Se-methylselenocysteine.
Topics: Animals; Anticarcinogenic Agents; Caspase 3; Caspases; Cell Division; Cell Movement; Cysteine; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Organoselenium Compounds; Osteopontin; Reverse Transcriptase Polymerase Chain Reaction; Selenocysteine; Sialoglycoproteins; Tumor Cells, Cultured | 2004 |
Insight into the polar reactivity of the onium chalcogen analogues of S-adenosyl-L-methionine.
Topics: Alkylating Agents; Biotransformation; Chalcogens; Cysteine; Escherichia coli; Humans; Methionine; Methionine Adenosyltransferase; Nuclear Magnetic Resonance, Biomolecular; Organoselenium Compounds; Protons; S-Adenosylmethionine; Selenocysteine; Selenomethionine; Stereoisomerism; Substrate Specificity; Sulfonium Compounds; Tellurium | 2004 |
Molecular and biochemical characterization of the selenocysteine Se-methyltransferase gene and Se-methylselenocysteine synthesis in broccoli.
Topics: Amino Acid Sequence; Brassica; Cloning, Molecular; Cysteine; DNA, Complementary; Escherichia coli; Gene Library; Methyltransferases; Molecular Sequence Data; Organoselenium Compounds; Recombinant Proteins; Selenocysteine; Sequence Alignment; Sequence Homology, Amino Acid | 2005 |
Irinotecan pharmacokinetic and pharmacogenomic alterations induced by methylselenocysteine in human head and neck xenograft tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Carcinoma, Squamous Cell; Cysteine; Female; Head and Neck Neoplasms; Humans; Irinotecan; Mice; Mice, Nude; Organoselenium Compounds; Pharmacogenetics; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Selenocysteine; Transplantation, Heterologous; Tumor Cells, Cultured | 2005 |
Se-methylselenocysteine inhibits phosphatidylinositol 3-kinase activity of mouse mammary epithelial tumor cells in vitro.
Topics: Animals; Anticarcinogenic Agents; Cell Division; Cell Line, Tumor; Cysteine; Enzyme Inhibitors; Epithelial Cells; Mammary Neoplasms, Animal; MAP Kinase Signaling System; Mice; Organoselenium Compounds; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Selenocysteine | 2005 |
[Effects of selenium and B-27 supplements on viability and differentiation of neural stem cell in newborn rat].
Topics: Animals; Animals, Newborn; Cell Differentiation; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Cysteine; Female; Glial Fibrillary Acidic Protein; Immunohistochemistry; Male; Neurons; Organoselenium Compounds; Rats; Rats, Wistar; Selenium; Selenocysteine; Sodium Selenite; Stem Cells; Tubulin | 2005 |
Potentiation of irinotecan sensitivity by Se-methylselenocysteine in an in vivo tumor model is associated with downregulation of cyclooxygenase-2, inducible nitric oxide synthase, and hypoxia-inducible factor 1alpha expression, resulting in reduced angiog
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Carcinoma, Squamous Cell; Cyclooxygenase 2; Cysteine; Down-Regulation; Female; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Irinotecan; Mice; Mice, Nude; Neovascularization, Pathologic; Nitric Oxide Synthase Type II; Organoselenium Compounds; Selenocysteine; Transplantation, Heterologous | 2006 |
Monomethylated selenium inhibits growth of LNCaP human prostate cancer xenograft accompanied by a decrease in the expression of androgen receptor and prostate-specific antigen (PSA).
Topics: Animals; Anticarcinogenic Agents; Cell Line, Tumor; Cell Proliferation; Cysteine; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Nude; Organoselenium Compounds; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Selenium; Selenocysteine; Xenograft Model Antitumor Assays | 2006 |
Se-methylselenocysteine enhances PMA-mediated CD11c expression via phospholipase D1 activation in U937 cells.
Topics: CD11c Antigen; Cell Differentiation; Cysteine; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Organoselenium Compounds; Phospholipase D; Selenocysteine; Tetradecanoylphorbol Acetate; U937 Cells; Up-Regulation | 2006 |
Mechanism for proliferation inhibition by various selenium compounds and selenium-enriched broccoli extract in rat glial cells.
Topics: Animals; Apoptosis; Brassica; Cell Line; Cell Proliferation; Cysteine; DNA Damage; Glutathione Peroxidase; Hydrogen Peroxide; Neuroglia; Organoselenium Compounds; Plant Extracts; Rats; Selenium Compounds; Selenocysteine; Selenomethionine | 2006 |
The mechanism of methylselenocysteine and docetaxel synergistic activity in prostate cancer cells.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cysteine; Docetaxel; Down-Regulation; Drug Synergism; Enzyme Activation; Inhibitor of Apoptosis Proteins; Male; Mice; Microtubule-Associated Proteins; Neoplasm Proteins; Organoselenium Compounds; Prostatic Neoplasms; Selenocysteine; Survivin; Taxoids | 2006 |
Metabolism of 76Se-methylselenocysteine compared with that of 77Se-selenomethionine and 82Se-selenite.
Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Cysteine; Dietary Supplements; Isotopes; Kidney; Liver; Male; Mass Spectrometry; Organoselenium Compounds; Pancreas; Rats; Rats, Wistar; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; Selenoproteins; Sodium Selenite; Time Factors | 2006 |
Selenium-tolerant diamondback moth disarms hyperaccumulator plant defense.
Topics: Adaptation, Physiological; Animals; Biological Evolution; Brassicaceae; Chromatography, Liquid; Cysteine; Drug Resistance; Genetic Speciation; Mass Spectrometry; Moths; Organoselenium Compounds; Oviposition; Selenocysteine; Spectrum Analysis; Wasps | 2006 |
Efficacy of increasing the therapeutic index of irinotecan, plasma and tissue selenium concentrations is methylselenocysteine dose dependent.
Topics: Administration, Oral; Animals; Bone Marrow; Camptothecin; Cysteine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Irinotecan; Kidney; Kinetics; Liver; Mice; Mice, Nude; Neoplasms; Organoselenium Compounds; Plasma; Selenium; Selenocysteine | 2007 |
Selenium accumulation protects plants from herbivory by Orthoptera via toxicity and deterrence.
Topics: Animals; Astragalus Plant; Brassicaceae; Cysteine; Ecosystem; Organoselenium Compounds; Orthoptera; Plant Leaves; Selenium; Selenocysteine | 2007 |
Elemental selenium at nano size (Nano-Se) as a potential chemopreventive agent with reduced risk of selenium toxicity: comparison with se-methylselenocysteine in mice.
Topics: Animals; Anticarcinogenic Agents; Biological Availability; Chemical and Drug Induced Liver Injury; Cysteine; Enzymes; Glutathione Transferase; Growth; Indicators and Reagents; Lethal Dose 50; Liver; Malondialdehyde; Mice; Mice, Inbred Strains; Nanoparticles; Nutritional Physiological Phenomena; Organoselenium Compounds; Selenium; Selenocysteine; Survival Analysis | 2008 |
Selenium methylselenocysteine protects human hepatoma HepG2 cells against oxidative stress induced by tert-butyl hydroperoxide.
Topics: Anticarcinogenic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cysteine; Glutathione; Humans; Liver Neoplasms; Malondialdehyde; Organoselenium Compounds; Oxidative Stress; Reactive Oxygen Species; Selenocysteine; tert-Butylhydroperoxide; Time Factors | 2007 |
Preferential organ distribution of methylselenol source Se-methylselenocysteine relative to methylseleninic acid.
Topics: Animals; Chromatography, High Pressure Liquid; Cysteine; Male; Mass Spectrometry; Organoselenium Compounds; Rats; Reference Standards; Selenocysteine; Tissue Distribution | 2008 |
Subchronic oral toxicity studies of Se-methylselenocysteine, an organoselenium compound for breast cancer prevention.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Breast Neoplasms; Cysteine; Dogs; Female; Liver; Male; Organoselenium Compounds; Rats; Selenocysteine | 2008 |
[Effects of Se-methylselenocysteine on biological behavior of and matrix metalloproteinase-2 expression in human breast cancer MDA-MB-231 cells].
Topics: Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cysteine; Female; Humans; Matrix Metalloproteinase 2; Organoselenium Compounds; RNA, Messenger; S Phase; Selenocysteine | 2008 |
Se-methylselenocysteine alters collagen gene and protein expression in human prostate cells.
Topics: Cell Line, Tumor; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type IV; Collagen Type VI; Collagen Type VII; Cysteine; Gene Expression; Humans; Male; Organoselenium Compounds; Prostate; RNA, Messenger; Selenocysteine; Sodium Selenite | 2008 |
Differential sensitivity of various human tumour-derived cell types to apoptosis by organic derivatives of selenium.
Topics: Adenocarcinoma; Adolescent; Adult; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cysteine; Epithelial Cells; Female; Humans; Liver Neoplasms; Male; Melanoma; Middle Aged; Neoplasms; Neuroectodermal Tumors, Primitive, Peripheral; Organoselenium Compounds; Selenium Compounds; Selenocysteine; Selenomethionine; Skin Neoplasms | 2009 |
Tumor vascular maturation and improved drug delivery induced by methylselenocysteine leads to therapeutic synergy with anticancer drugs.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Capillary Permeability; Carcinoma, Squamous Cell; Cysteine; Drug Delivery Systems; Drug Synergism; Female; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Neovascularization, Pathologic; Organoselenium Compounds; Selenocysteine; Xenograft Model Antitumor Assays | 2008 |
Hypoxia-specific drug tirapazamine does not abrogate hypoxic tumor cells in combination therapy with irinotecan and methylselenocysteine in well-differentiated human head and neck squamous cell carcinoma a253 xenografts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Squamous Cell; Cell Differentiation; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cysteine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Forkhead Transcription Factors; Head and Neck Neoplasms; Humans; Irinotecan; Maximum Tolerated Dose; Mice; Mice, Nude; Neoplasm Transplantation; Organoselenium Compounds; Selenocysteine; Tirapazamine; Triazines; Xenograft Model Antitumor Assays | 2008 |
Long exposure of non-cytotoxic concentrations of methylselenol suppresses the invasive potential of B16F10 melanoma.
Topics: Animals; Cell Adhesion; Cell Movement; Cell Survival; Cysteine; Dietary Supplements; Female; Fibronectins; Flow Cytometry; Gelatinases; Humans; Integrin alphaVbeta3; Integrins; Lung Neoplasms; Melanoma, Experimental; Methanol; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Organoselenium Compounds; Selenocysteine; Sodium Selenite; Survival Rate; Tumor Cells, Cultured; Vitronectin; Wound Healing | 2008 |
Combination of methylselenocysteine with tamoxifen inhibits MCF-7 breast cancer xenografts in nude mice through elevated apoptosis and reduced angiogenesis.
Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cell Division; Cyclin D1; Cysteine; Drug Synergism; Estradiol; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Neovascularization, Pathologic; Organoselenium Compounds; Random Allocation; Receptors, Progesterone; Selenocysteine; Specific Pathogen-Free Organisms; Tamoxifen; Xenograft Model Antitumor Assays | 2009 |
Dietary supplementation with selenomethylselenocysteine produces a differential proteomic response.
Topics: Animals; Cysteine; Dietary Supplements; Electrophoresis, Gel, Two-Dimensional; Female; Male; Organoselenium Compounds; Proteomics; Rats; Rats, Wistar; Selenium; Selenocysteine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2009 |
Differential action of methylselenocysteine in control and alloxan-diabetic rabbits.
Topics: Albuminuria; Animals; Blood Glucose; Body Weight; Creatinine; Cysteine; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Kidney; Kidney Diseases; Liver; Male; Necrosis; Organoselenium Compounds; Oxidoreductases; Rabbits; Selenium; Selenocysteine; Urea | 2009 |
Accumulation of an organic anticancer selenium compound in a transgenic Solanaceous species shows wider applicability of the selenocysteine methyltransferase transgene from selenium hyperaccumulators.
Topics: Anticarcinogenic Agents; Cysteine; Methyltransferases; Nicotiana; Organoselenium Compounds; Plant Proteins; Plants, Genetically Modified; Selenocysteine; Sulfate Adenylyltransferase; Transgenes | 2009 |
Separation and determination of seleno amino acids using gas chromatography hyphenated with inductively coupled plasma mass spectrometry after hollow fiber liquid phase microextraction.
Topics: Agaricales; Brassica; Chemical Fractionation; Chloroform; Cysteine; Ethionine; Garlic; Gas Chromatography-Mass Spectrometry; Organoselenium Compounds; Selenocysteine; Selenomethionine; Sensitivity and Specificity; Sodium Chloride; Toluene | 2009 |
Chemopreventive doses of methylselenocysteine alter circadian rhythm in rat mammary tissue.
Topics: Animals; Breast Neoplasms; Carcinoma; Cell Cycle Proteins; Chemoprevention; Circadian Rhythm; Cysteine; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Mammary Glands, Animal; Methylnitrosourea; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Organoselenium Compounds; Period Circadian Proteins; Rats; Rats, Inbred F344; Selenium; Selenocysteine; Specific Pathogen-Free Organisms | 2008 |
Selenium metabolism in rats with long-term ingestion of Se-methylselenocysteine using enriched stable isotopes.
Topics: Animals; Cysteine; Isotopes; Kidney; Liver; Male; Organoselenium Compounds; Rats; Rats, Wistar; Selenium; Selenocysteine; Tissue Distribution | 2009 |
Se-methylselenocysteine sensitized TRAIL-mediated apoptosis via down-regulation of Bcl-2 expression.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma; Caspases; Cysteine; Down-Regulation; Drug Evaluation, Preclinical; Drug Synergism; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Kidney Neoplasms; Organoselenium Compounds; Peptide Fragments; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Selenocysteine; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured | 2009 |
Methyl-selenium compounds inhibit prostate carcinogenesis in the transgenic adenocarcinoma of mouse prostate model with survival benefit.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Proliferation; Cysteine; Enzyme-Linked Immunosorbent Assay; In Situ Nick-End Labeling; Insulin-Like Growth Factor I; Male; Mice; Mice, Transgenic; Organoselenium Compounds; Prostatic Neoplasms; Selenocysteine; Selenomethionine | 2009 |
Antiproliferative effects of selenium compounds in colon cancer cells: comparison of different cytotoxicity assays.
Topics: Anticarcinogenic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cysteine; Cytotoxins; Humans; Methionine; Organoselenium Compounds; Selenocysteine; Sodium Selenite; Toxicity Tests | 2009 |
Inhibition of colon cancer growth by methylselenocysteine-induced angiogenic chemomodulation is influenced by histologic characteristics of the tumor.
Topics: Animals; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Cell Differentiation; Colon; Colorectal Neoplasms; Cysteine; Doxorubicin; Drug Delivery Systems; Drug Resistance, Neoplasm; Female; Humans; Hypoxia; Immunoenzyme Techniques; Magnetic Resonance Imaging; Mice; Mice, Nude; Neovascularization, Pathologic; Organoselenium Compounds; Selenocysteine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2009 |
Speciation analysis of selenium metabolites in urine and breath by HPLC- and GC-inductively coupled plasma-MS after administration of selenomethionine and methylselenocysteine to rats.
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Cysteine; Exhalation; Gas Chromatography-Mass Spectrometry; Male; Organoselenium Compounds; Rats; Rats, Wistar; Selenium Compounds; Selenocysteine; Selenomethionine | 2009 |
Organic and inorganic selenium compounds produce different protein patterns in the blood plasma of rats.
Topics: Animals; Blood Proteins; Cysteine; Dietary Supplements; Electrophoresis, Gel, Two-Dimensional; Male; Mass Spectrometry; Organoselenium Compounds; Rats; Rats, Wistar; Selenic Acid; Selenium; Selenium Compounds; Selenocysteine | 2009 |
In vitro radioprotection studies of organoselenium compounds: differences between mono- and diselenides.
Topics: Animals; Cattle; Cell Line, Tumor; Cysteine; Cystine; DNA; DNA Damage; Gamma Rays; Lipid Peroxidation; Liposomes; Lymphocytes; Lymphoma; Mice; Mice, Inbred C57BL; Organoselenium Compounds; Protein Carbonylation; Radiation-Protective Agents; Selenocysteine; Selenomethionine; Serum Albumin, Bovine; Thiobarbituric Acid Reactive Substances; Thymus Neoplasms | 2009 |
Speciation of selenium dietary supplements; formation of S-(methylseleno)cysteine and other selenium compounds.
Topics: Chromatography, High Pressure Liquid; Cysteine; Dietary Supplements; Gas Chromatography-Mass Spectrometry; Organoselenium Compounds; Selenium Compounds; Selenocysteine; Spectrometry, Mass, Electrospray Ionization; Temperature | 2009 |
Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.
Topics: Antitubercular Agents; Cysteine; Drug Evaluation, Preclinical; Mycobacterium; Mycobacterium smegmatis; Organoselenium Compounds; Selenocysteine; Small Molecule Libraries | 2009 |
Differential apoptotic response of human cancer cells to organoselenium compounds.
Topics: Anticarcinogenic Agents; Apoptosis; Blotting, Western; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Flow Cytometry; Humans; Neoplasms; Organoselenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite; Tumor Suppressor Protein p53 | 2010 |
Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1alpha.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Cysteine; Drug Delivery Systems; Female; Gene Knockdown Techniques; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Irinotecan; Mice; Mice, Nude; Organoselenium Compounds; Reactive Oxygen Species; RNA, Small Interfering; Selenocysteine; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2010 |
Interleukin-10 delivery via mesenchymal stem cells: a novel gene therapy approach to prevent lung ischemia-reperfusion injury.
Topics: Animals; Bronchoalveolar Lavage Fluid; Caspase 3; Cysteine; Genetic Therapy; Genetic Vectors; Hematopoietic Stem Cells; Interleukin-10; Lung; Lung Transplantation; Male; Mesenchymal Stem Cells; Organoselenium Compounds; Rats; Rats, Inbred Lew; Reperfusion Injury; Selenocysteine | 2010 |
Selenium compounds activate early barriers of tumorigenesis.
Topics: Anticarcinogenic Agents; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cellular Senescence; Cysteine; DNA Damage; DNA Repair; DNA-Binding Proteins; Histones; Humans; Male; Neoplasms; Organoselenium Compounds; Oxidative Stress; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Selenium Compounds; Selenocysteine; Sodium Selenite; Tumor Suppressor Proteins | 2010 |
Methylselenocysteine resets the rhythmic expression of circadian and growth-regulatory genes disrupted by nitrosomethylurea in vivo.
Topics: Administration, Oral; Alkylating Agents; Animals; Anticarcinogenic Agents; Blotting, Western; Cell Proliferation; Circadian Rhythm; Cysteine; Diet; Female; Gene Expression; Gene Expression Regulation; Immunohistochemistry; Mammary Glands, Animal; Methylnitrosourea; Organoselenium Compounds; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Selenocysteine | 2010 |
Anti-hemolytic and peroxyl radical scavenging activity of organoselenium compounds: an in vitro study.
Topics: Cysteine; Cystine; Erythrocytes; Free Radical Scavengers; Hemolysis; Humans; Lipid Peroxidation; Organoselenium Compounds; Oxidation-Reduction; Peroxides; Selenocysteine; Selenomethionine | 2011 |
Selenium, but not lycopene or vitamin E, decreases growth of transplantable dunning R3327-H rat prostate tumors.
Topics: Androgens; Animals; Carotenoids; Cell Proliferation; Cysteine; Lycopene; Male; Neoplasm Transplantation; Organoselenium Compounds; Prostatic Neoplasms; Rats; Selenium; Selenocysteine; Tumor Burden; Vitamin E | 2010 |
The von Hippel-Lindau (VHL) tumor-suppressor gene is down-regulated by selenium deficiency in Caco-2 cells and rat colon mucosa.
Topics: Animals; Caco-2 Cells; Cell Line, Tumor; Colon; Cysteine; DNA Methylation; Glutathione Peroxidase; Humans; Liver; Male; Mucous Membrane; Organoselenium Compounds; Promoter Regions, Genetic; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Selenium; Selenocysteine; Von Hippel-Lindau Tumor Suppressor Protein | 2011 |
Proteomic profiling of potential molecular targets of methyl-selenium compounds in the transgenic adenocarcinoma of mouse prostate model.
Topics: Adenocarcinoma; Animals; Biomarkers, Pharmacological; Biomarkers, Tumor; Cysteine; Disease Models, Animal; Male; Metabolome; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Organoselenium Compounds; Prostatic Neoplasms; Proteomics; Selenium Compounds; Selenocysteine; Selenomethionine | 2010 |
Survivin gene silencing sensitizes prostate cancer cells to selenium growth inhibition.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cysteine; Down-Regulation; Drug Synergism; Gene Silencing; Humans; Immunoenzyme Techniques; Inhibitor of Apoptosis Proteins; Male; Mice; Mice, Nude; Neoplasms, Hormone-Dependent; Organoselenium Compounds; Prognosis; Prostatic Neoplasms; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selenocysteine; Survival Rate; Survivin | 2010 |
Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells.
Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Anticarcinogenic Agents; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; Colorectal Neoplasms; Cysteine; DNA Breaks; DNA Mismatch Repair; DNA Repair Enzymes; DNA-Binding Proteins; Drug Resistance, Neoplasm; Guanosine; Humans; Mismatch Repair Endonuclease PMS2; Morpholines; MutL Protein Homolog 1; Nuclear Proteins; Organoselenium Compounds; Piperidines; Protein Serine-Threonine Kinases; Pyrones; Reactive Oxygen Species; Selenocysteine; Sodium Selenite; Tumor Suppressor Proteins | 2010 |
Simultaneous analysis of mercury and selenium species including chiral forms of selenomethionine in human urine and serum by HPLC column-switching coupled to ICP-MS.
Topics: Chromatography, High Pressure Liquid; Cysteine; Cystine; Dietary Supplements; Humans; Mass Spectrometry; Mercury; Methylmercury Compounds; Organoselenium Compounds; Selenic Acid; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite; Stereoisomerism | 2010 |
Selenium hyperaccumulation offers protection from cell disruptor herbivores.
Topics: Animals; Astragalus Plant; Brassicaceae; Cysteine; Food Preferences; Insecta; Organoselenium Compounds; Selenium; Selenocysteine; Tetranychidae | 2010 |
Chemical form of selenium affects its uptake, transport, and glutathione peroxidase activity in the human intestinal Caco-2 cell model.
Topics: Alanine; Caco-2 Cells; Cysteine; Enzyme Activation; Glutathione Peroxidase; Humans; Organoselenium Compounds; Selenium; Selenocysteine; Sodium Selenite | 2011 |
Se-methylselenocysteine inhibits lipopolysaccharide-induced NF-κB activation and iNOS induction in RAW 264.7 murine macrophages.
Topics: Animals; Anticarcinogenic Agents; Cells, Cultured; Cysteine; Enzyme Induction; I-kappa B Proteins; Lipopolysaccharides; Macrophages; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; Organoselenium Compounds; Phosphorylation; RNA, Messenger; Selenocysteine | 2011 |
Uptake, distribution, and speciation of selenoamino acids by human cancer cells: X-ray absorption and fluorescence methods.
Topics: Cell Line, Tumor; Cysteine; Humans; Microscopy, Fluorescence; Neoplasms; Organoselenium Compounds; Selenocysteine; Selenomethionine; X-Ray Absorption Spectroscopy | 2011 |
Lobe-specific lineages of carcinogenesis in the transgenic adenocarcinoma of mouse prostate and their responses to chemopreventive selenium.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Cell Lineage; Cysteine; Disease Models, Animal; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Metastasis; Organoselenium Compounds; Prostatic Neoplasms; Proteomics; Selenocysteine; Seminal Vesicles | 2011 |
Magnetic resonance and fluorescence-protein imaging of the anti-angiogenic and anti-tumor efficacy of selenium in an orthotopic model of human colon cancer.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Cysteine; Diagnostic Imaging; Female; Green Fluorescent Proteins; Humans; Magnetic Resonance Imaging; Mice; Mice, Nude; Microvessels; Neovascularization, Pathologic; Organoselenium Compounds; Random Allocation; Selenocysteine; Xenograft Model Antitumor Assays | 2011 |
Metabolic and bioprocess engineering for production of selenized yeast with increased content of seleno-methylselenocysteine.
Topics: Astragalus Plant; Cysteine; Genetic Engineering; Methyltransferases; Organoselenium Compounds; Plant Proteins, Dietary; Recombinant Proteins; Saccharomyces cerevisiae; Selenocysteine | 2011 |
Mouse prostate proteomes are differentially altered by supranutritional intake of four selenium compounds.
Topics: Animals; Anticarcinogenic Agents; Cysteine; Gene Expression Profiling; Gene Expression Regulation; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Organoselenium Compounds; Prostate; Prostatic Neoplasms; Protein Biosynthesis; Proteomics; RNA, Messenger; Selenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite; Xenograft Model Antitumor Assays | 2011 |
Distribution of Se and its species in Myriophyllum spicatum and Ceratophyllum demersum growing in water containing Se (VI).
Topics: Chlorophyll; Chlorophyll A; Chromatography, High Pressure Liquid; Cysteine; Cystine; Magnoliopsida; Mass Spectrometry; Organoselenium Compounds; Photosystem II Protein Complex; Selenic Acid; Selenium Compounds; Selenocysteine; Selenomethionine; Water | 2011 |
Augmented therapeutic efficacy of irinotecan is associated with enhanced drug accumulation.
Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Chromatography, High Pressure Liquid; Cysteine; Drug Synergism; Female; Humans; Immunohistochemistry; Irinotecan; Mice; Mice, Nude; Neoplasms, Experimental; Organoselenium Compounds; Selenocysteine; Xenograft Model Antitumor Assays | 2011 |
Biofortification of tomato (Solanum lycopersicum) fruit with the anticancer compound methylselenocysteine using a selenocysteine methyltransferase from a selenium hyperaccumulator.
Topics: Antineoplastic Agents; Cysteine; Food, Fortified; Fruit; Gene Expression; Methyltransferases; Organoselenium Compounds; Plants, Genetically Modified; Selenic Acid; Selenium; Selenium Compounds; Selenocysteine; Sodium Selenite; Solanum lycopersicum | 2011 |
Analysis of selenomethylselenocysteine and selenomethionine by LC-ESI-MS/MS with diethyl ethoxymethylenemalonate derivatization.
Topics: Chromatography, High Pressure Liquid; Cysteine; Malonates; Mercaptoethanol; Onions; Organoselenium Compounds; Oxidation-Reduction; Selenocysteine; Selenomethionine; Spectrometry, Mass, Electrospray Ionization | 2011 |
Methylselenocysteine treatment leads to diselenide formation in human cancer cells: evidence from X-ray absorption spectroscopy studies.
Topics: Antineoplastic Agents; Benzene Derivatives; Cell Line, Tumor; Cysteine; Humans; Organoselenium Compounds; Selenium Compounds; Selenocysteine; X-Ray Absorption Spectroscopy | 2012 |
Selenium is a modulator of circadian clock that protects mice from the toxicity of a chemotherapeutic drug via upregulation of the core clock protein, BMAL1.
Topics: Animals; ARNTL Transcription Factors; Cell Line, Tumor; Circadian Clocks; CLOCK Proteins; Cyclophosphamide; Cysteine; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Neoplasms; Organoselenium Compounds; Period Circadian Proteins; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Selenium Compounds; Selenocysteine; Transcription Factors; Transcription, Genetic; Transcriptional Activation | 2011 |
A reliable solid phase microextraction-gas chromatography-triple quadrupole mass spectrometry method for the assay of selenomethionine and selenomethylselenocysteine in aqueous extracts: difference between selenized and not-enriched selenium potatoes.
Topics: Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Plant Extracts; Reproducibility of Results; Research Design; Selenium; Selenocysteine; Selenomethionine; Solanum tuberosum; Solid Phase Microextraction; Tandem Mass Spectrometry; Water | 2012 |
The preventive effect of Se-methylselenocysteine on γ-radiation-induced oxidative stress in rat lungs.
Topics: Animals; Antioxidants; Gamma Rays; Glutathione; Lipid Peroxidation; Lung; Male; NF-E2-Related Factor 2; Oxidative Stress; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Selenocysteine | 2013 |
Analysis of animal and plant selenometabolites in roots of a selenium accumulator, Brassica rapa var. peruviridis, by speciation.
Topics: Animals; Brassica rapa; Chromatography, High Pressure Liquid; Metabolic Networks and Pathways; Organoselenium Compounds; Plant Extracts; Plant Roots; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; Spectrometry, Mass, Electrospray Ionization; Water | 2013 |
Combination effects of dietary soy and methylselenocysteine in a mouse model of prostate cancer.
Topics: Animals; Cell Transformation, Neoplastic; Diet; Dietary Supplements; Disease Models, Animal; Female; Gene Expression; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Prostatic Neoplasms; Receptors, Androgen; Selenocysteine; Soy Foods | 2013 |
Selenium for the prevention of cutaneous melanoma.
Topics: Animals; Cell Cycle; Cell Line, Tumor; Cell Survival; Female; Human Growth Hormone; Humans; Male; Melanoma; Mice; Mice, Transgenic; Organoselenium Compounds; Proportional Hazards Models; RNA; Selenium; Selenocysteine; Skin Neoplasms; Sodium Selenite; Ultraviolet Rays | 2013 |
Determination of selenomethionine and seleno-methyl-selenocysteine in biota by ultrasonic-assisted enzymatic digestion and multi-shot stir bar sorptive extraction-thermal desorption-gas chromatography-mass spectrometry.
Topics: Absorption; Animals; Biota; Bivalvia; Ethanol; Gas Chromatography-Mass Spectrometry; Haptophyta; Linear Models; Lipase; Pronase; Pyridines; Selenocysteine; Selenomethionine; Sonication | 2013 |
A simplified method for inorganic selenium and selenoaminoacids speciation based on HPLC-TR-HG-AFS.
Topics: Bromides; Chromatography, High Pressure Liquid; Cystine; Hot Temperature; Limit of Detection; Organoselenium Compounds; Oxidation-Reduction; Potassium Compounds; Reproducibility of Results; Selenic Acid; Selenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite; Solutions; Spectrometry, Fluorescence; Spectrophotometry, Atomic | 2013 |
Changes in SeMSC, glucosinolates and sulforaphane levels, and in proteome profile in broccoli (Brassica oleracea var. Italica) fertilized with sodium selenate.
Topics: Antioxidants; Brassica; Glucosinolates; Isothiocyanates; Plant Proteins; Proteome; Selenic Acid; Selenium Compounds; Selenocysteine; Sulfoxides; Thiocyanates | 2013 |
Assessment of the anticancer compounds Se-methylselenocysteine and glucosinolates in Se-biofortified broccoli (Brassica oleracea L. var. italica) sprouts and florets.
Topics: Anticarcinogenic Agents; Brassica; Fertilizers; Glucosinolates; Hydroponics; Inflorescence; Plant Shoots; Selenium Compounds; Selenocysteine | 2013 |
Molecular mechanisms involved in the protective effect of selenocystine against methylmercury-induced cell death in human HepG2 cells.
Topics: Apoptosis; Cell Proliferation; Cell Survival; Cystine; Environmental Pollutants; Glutathione; Hep G2 Cells; Hepatocytes; Humans; MAP Kinase Signaling System; Methylmercury Compounds; Organoselenium Compounds; Osmolar Concentration; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Protective Agents; Reactive Oxygen Species; Selenocysteine; Selenomethionine | 2013 |
Chemical characterisation and speciation of organic selenium in cultivated selenium-enriched Agaricus bisporus.
Topics: Agaricus; Cystine; Organoselenium Compounds; Selenium; Selenocysteine; Selenomethionine | 2013 |
Effects of selenium on development, survival, and accumulation in the honeybee (Apis mellifera L.).
Topics: Animals; Bees; Cystine; Environmental Pollutants; Larva; Organoselenium Compounds; Pollination; Selenic Acid; Selenious Acid; Selenium Compounds; Selenocysteine | 2013 |
Evaluation of selenium species in selenium-enriched pakchoi (Brassica chinensis Jusl var parachinensis (Bailey) Tsen & Lee) using mixed ion-pair reversed phase HPLC-ICP-MS.
Topics: Alkanesulfonic Acids; Brassica; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Hydrogen-Ion Concentration; Mass Spectrometry; Plant Extracts; Selenic Acid; Selenious Acid; Selenium Compounds; Selenocysteine; Selenomethionine | 2014 |
The relationship of selenium tolerance and speciation in Lecythidaceae species.
Topics: Lecythidaceae; Mass Spectrometry; Organoselenium Compounds; Selenium; Selenocysteine; Selenomethionine | 2013 |
Evaluation of the respiratory elimination kinetics of selenate and Se-methylselenocysteine after oral administration in lambs.
Topics: Administration, Oral; Animals; Breath Tests; Dose-Response Relationship, Drug; Exhalation; Selenic Acid; Selenocysteine; Sheep | 2013 |
Se-methylselenocysteine offers selective protection against toxicity and potentiates the antitumour activity of anticancer drugs in preclinical animal models.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Cyclophosphamide; Cytoprotection; Female; Humans; Irinotecan; Mice; Mice, Nude; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Rats; Rats, Inbred F344; Selenocysteine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2014 |
Biological and chemical investigation of Allium cepa L. response to selenium inorganic compounds.
Topics: Chromatography, High Pressure Liquid; Mass Spectrometry; Mitosis; Onions; Oxygen; Plant Roots; Selenium; Selenium Compounds; Selenocysteine; Temperature | 2014 |
Preconcentration of seleno-amino acids on a XAD resin and determination in regional olive oils by SPE UPLC-ESI-MS/MS.
Topics: Chromatography, High Pressure Liquid; Limit of Detection; Olive Oil; Plant Oils; Polystyrenes; Polyvinyls; Selenocysteine; Selenomethionine; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |
A high isoflavone diet decreases 5' adenosine monophosphate-activated protein kinase activation and does not correct selenium-induced elevations in fasting blood glucose in mice.
Topics: AMP-Activated Protein Kinases; Animals; Blood Glucose; Diet; Dietary Supplements; Fasting; Glucose Intolerance; Insulin Resistance; Isoflavones; Liver; Male; Mice; Mice, Inbred Strains; Muscle, Skeletal; Plant Extracts; Selenium; Selenocysteine | 2014 |
Large-scale, protection-free synthesis of Se-adenosyl-L-selenomethionine analogues and their application as cofactor surrogates of methyltransferases.
Topics: Methyltransferases; Molecular Structure; Selenocysteine; Selenomethionine | 2014 |
Impact of selenium supply on Se-methylselenocysteine and glucosinolate accumulation in selenium-biofortified Brassica sprouts.
Topics: Amino Acids; Anticarcinogenic Agents; Brassica; Chromatography, Liquid; Food, Fortified; Glucosinolates; Imidoesters; Oximes; Selenium; Selenium Compounds; Selenocysteine; Sulfoxides; Sulfur; Tandem Mass Spectrometry; Vegetables | 2014 |
Maintaining tissue selenium species distribution as a potential defense mechanism against methylmercury toxicity in juvenile white sturgeon (Acipenser transmontanus).
Topics: Animals; Fishes; Kidney; Liver; Mercury; Methylmercury Compounds; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; Tissue Distribution; Water Pollutants, Chemical | 2014 |
Synergistic effect of Se-methylselenocysteine and vitamin E in ameliorating the acute ethanol-induced oxidative damage in rat.
Topics: Animals; Antioxidants; Ethanol; Female; Glutathione; Glutathione Peroxidase; Malondialdehyde; Oxidative Stress; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Selenocysteine; Superoxide Dismutase; Vitamin E | 2015 |
Synthesis of [(77)Se]-methylselenocysteine when preparing sauerkraut in the presence of [(77)Se]-selenite. Metabolic transformation of [ (77)Se]-methylselenocysteine in Wistar rats determined by LC-IDA-ICP-MS.
Topics: Animal Feed; Animals; Chromatography, High Pressure Liquid; Kidney; Liver; Male; Mass Spectrometry; Myocardium; Rats; Rats, Wistar; Selenious Acid; Selenium; Selenocysteine | 2014 |
Se-methylselenocysteine inhibits apoptosis induced by clusterin knockdown in neuroblastoma N2a and SH-SY5Y cell lines.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 8; Cell Line; Cell Line, Tumor; Cell Survival; Clusterin; Down-Regulation; Humans; Mice; Neuroblastoma; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Selenium; Selenocysteine; Up-Regulation | 2014 |
Safety evaluation of Se-methylselenocysteine as nutritional selenium supplement: acute toxicity, genotoxicity and subchronic toxicity.
Topics: Animals; Dietary Supplements; Dose-Response Relationship, Drug; Female; Humans; Lethal Dose 50; Male; Mice, Inbred BALB C; Models, Biological; Mutagenicity Tests; No-Observed-Adverse-Effect Level; Rats, Sprague-Dawley; Selenium; Selenocysteine; Spermatozoa; Toxicity Tests, Acute; Toxicity Tests, Subchronic | 2014 |
Trans-sulfuration Pathway Seleno-amino Acids Are Mediators of Selenomethionine Toxicity in Saccharomyces cerevisiae.
Topics: Amino Acids, Sulfur; Dietary Supplements; DNA Repair; Humans; Metabolic Networks and Pathways; Methionine; Mutation; Oxidative Stress; S-Adenosylmethionine; Saccharomyces cerevisiae; Selenious Acid; Selenium Compounds; Selenocysteine; Selenomethionine | 2015 |
Methylselenocysteine preventing castration-resistant progression of prostate cancer.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Disease Progression; Humans; Immunohistochemistry; Male; Mice; Mice, Nude; Prostate-Specific Antigen; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Random Allocation; Receptors, Androgen; Selenocysteine; Xenograft Model Antitumor Assays | 2015 |
Se-Methyl-L-selenocysteine Induces Apoptosis via Endoplasmic Reticulum Stress and the Death Receptor Pathway in Human Colon Adenocarcinoma COLO 205 Cells.
Topics: Adenocarcinoma; Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Colonic Neoplasms; Endoplasmic Reticulum Stress; Humans; Poly(ADP-ribose) Polymerases; Selenocysteine; Transcription Factor CHOP | 2015 |
[Effects of selenium compounds on proliferation, migration and adhesion of HeLa cells].
Topics: Anticarcinogenic Agents; Cell Movement; HeLa Cells; Humans; Organoselenium Compounds; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine | 2015 |
Analysis of Selenium Levels in Osteosarcoma Patients and the Effects of Se-Methylselenocysteine on Osteosarcoma Cells In Vitro.
Topics: Adolescent; Adult; Aged; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Bone Neoplasms; Cell Cycle; Cell Line, Tumor; Child; Drug Evaluation, Preclinical; Female; Genes, bcl-2; Humans; Male; Middle Aged; Osteosarcoma; Selenium; Selenocysteine; Young Adult | 2015 |
Validation of a Stability-Indicating Method for Methylseleno-L-Cysteine (L-SeMC).
Topics: Animals; Chromatography, Liquid; Limit of Detection; Rats; Reference Standards; Selenocysteine | 2016 |
Effects of Selenium Yeast on Oxidative Stress, Growth Inhibition, and Apoptosis in Human Breast Cancer Cells.
Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Female; Glutathione Peroxidase; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial; Organoselenium Compounds; Oxidative Stress; Reactive Oxygen Species; Selenium; Selenocysteine; Superoxide Dismutase; Yeasts | 2015 |
Se-Allylselenocysteine induces autophagy by modulating the AMPK/mTOR signaling pathway and epigenetic regulation of PCDH17 in human colorectal adenocarcinoma cells.
Topics: Adenocarcinoma; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Autophagy; Cadherins; Colorectal Neoplasms; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Mice, Inbred BALB C; Promoter Regions, Genetic; Selenocysteine; Signal Transduction; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2015 |
The response of broccoli (Brassica oleracea convar. italica) varieties on foliar application of selenium: uptake, translocation, and speciation.
Topics: Biological Transport; Brassica; Cations, Divalent; Cations, Monovalent; Cystine; Flowers; Organoselenium Compounds; Plant Leaves; Plant Roots; Plant Stems; Selenium Compounds; Selenocysteine; Selenomethionine; Spectrophotometry, Atomic | 2015 |
Enhancement of NAD⁺-dependent SIRT1 deacetylase activity by methylselenocysteine resets the circadian clock in carcinogen-treated mammary epithelial cells.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Chromatin Immunoprecipitation; Circadian Clocks; Epigenesis, Genetic; Epithelial Cells; Female; Humans; Mammary Glands, Animal; Mammary Glands, Human; Methylnitrosourea; NAD; Rats; Rats, Inbred F344; Real-Time Polymerase Chain Reaction; Selenocysteine; Sirtuin 1; Transfection | 2015 |
Determination of seleno-amino acids bound to proteins in extra virgin olive oils.
Topics: Olive Oil; Plant Proteins; Selenocysteine; Solvents | 2016 |
Selenium Plays a Protective Role in Staphylococcus aureus-Induced Endometritis in the Uterine Tissue of Rats.
Topics: Animals; Endometriosis; Female; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Selenium; Selenocysteine; Staphylococcal Infections; Staphylococcus aureus; Uterus | 2016 |
[Production effect comparison of SEPP and GPx between HepG2 and Hela cells with different selenocompounds].
Topics: Glutathione; HeLa Cells; Hep G2 Cells; Humans; Selenium Compounds; Selenocysteine; Selenomethionine; Selenoproteins | 2016 |
Differing cytotoxicity and bioavailability of selenite, methylselenocysteine, selenomethionine, selenosugar 1 and trimethylselenonium ion and their underlying metabolic transformations in human cells.
Topics: Biological Availability; Cell Line, Tumor; Hep G2 Cells; Humans; Limit of Detection; Neuroglia; Selenious Acid; Selenium Compounds; Selenocysteine; Selenomethionine; Urothelium | 2016 |
Evaluation of selenium in dietary supplements using elemental speciation.
Topics: Dietary Supplements; Dose-Response Relationship, Drug; Selenic Acid; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine | 2017 |
Antioxidant Actions of Selenium in Orbital Fibroblasts: A Basis for the Effects of Selenium in Graves' Orbitopathy.
Topics: Aged; Antioxidants; Case-Control Studies; Cell Proliferation; Cells, Cultured; Cytokines; Female; Fibroblasts; Glutathione Disulfide; Glutathione Peroxidase; Graves Ophthalmopathy; Humans; Hyaluronic Acid; Hydrogen Peroxide; Male; Middle Aged; Orbit; Oxidants; Oxidative Stress; Selenium; Selenocysteine | 2017 |
Selective Cytotoxic Activity of Se-Methyl-Seleno-L-Cysteine- and Se-Polysaccharide-Containing Extracts from Shiitake Medicinal Mushroom, Lentinus edodes (Agaricomycetes).
Topics: Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Survival; HeLa Cells; Humans; Mycelium; Polysaccharides; Selenocysteine; Shiitake Mushrooms | 2017 |
Effects of Chinese Cooking Methods on the Content and Speciation of Selenium in Selenium Bio-Fortified Cereals and Soybeans.
Topics: China; Cooking; Cystine; Edible Grain; Food Analysis; Food, Fortified; Glycine max; Organoselenium Compounds; Selenium; Selenocysteine; Selenomethionine; Soy Milk | 2018 |
Se-Methylselenocysteine Ameliorates Neuropathology and Cognitive Deficits by Attenuating Oxidative Stress and Metal Dyshomeostasis in Alzheimer Model Mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cognitive Dysfunction; Disease Models, Animal; Homeostasis; Male; MAP Kinase Signaling System; Metals; Mice, Transgenic; Neurons; Oxidative Stress; Phosphorylation; Selenocysteine; Spatial Memory; tau Proteins | 2018 |
Selenium species-dependent toxicity, bioavailability and metabolic transformations in Caenorhabditis elegans.
Topics: Animals; Biological Availability; Caenorhabditis elegans; Selenious Acid; Selenocysteine; Selenomethionine; Thioredoxin Reductase 1 | 2018 |
Effect of administration route and dose on metabolism of nine bioselenocompounds.
Topics: Administration, Oral; Animals; Chromatography, Liquid; Cyanates; Cystine; Gastrointestinal Microbiome; Glutathione Peroxidase; Male; Mass Spectrometry; Organoselenium Compounds; Rats; Rats, Wistar; Selenium Compounds; Selenocysteine; Selenomethionine; Selenoproteins | 2018 |
Methylation of selenocysteine catalysed by thiopurine S-methyltransferase.
Topics: Catalysis; Catalytic Domain; Humans; Kinetics; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Molecular Conformation; Molecular Docking Simulation; Protein Binding; Protein Processing, Post-Translational; Recombinant Proteins; Selenium; Selenocysteine | 2019 |
Non-Coding Micro RNAs and Hypoxia-Inducible Factors Are Selenium Targets for Development of a Mechanism-Based Combination Strategy in Clear-Cell Renal Cell Carcinoma-Bench-to-Bedside Therapy.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Basic Helix-Loop-Helix Transcription Factors; Carcinoma, Renal Cell; Cell Line, Tumor; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Neoplasms; Mice, Nude; MicroRNAs; Selenocysteine; Selenomethionine; Topotecan | 2018 |
Anti-cholinergics mecamylamine and scopolamine alleviate motion sickness-induced gastrointestinal symptoms through both peripheral and central actions.
Topics: Animals; Behavior, Animal; Cats; Cholinergic Antagonists; Hexamethonium; Hypothermia, Induced; Male; Mecamylamine; Models, Animal; Motion Sickness; Muscarinic Antagonists; Nausea; Neurons; Nicotinic Antagonists; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Scopolamine; Selenocysteine; Vomiting | 2019 |
Treatment of Caenorhabditis elegans with Small Selenium Species Enhances Antioxidant Defense Systems.
Topics: Animals; Antioxidants; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Gene Expression Regulation; Mutation; Selenious Acid; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; tert-Butylhydroperoxide; Thioredoxin Reductase 1 | 2019 |
Assessing bioaccessibility of Se and I in dual biofortified radish seedlings using simulated in vitro digestion.
Topics: Anticarcinogenic Agents; Biofortification; Biological Availability; Cystine; Digestion; Iodine; Organoselenium Compounds; Raphanus; Seedlings; Selenium; Selenocysteine; Selenomethionine | 2019 |
Side-Directed Transfer and Presystemic Metabolism of Selenoneine in a Human Intestinal Barrier Model.
Topics: Biological Transport; Caco-2 Cells; Histidine; Humans; Intestinal Mucosa; Organoselenium Compounds; Permeability; Selenious Acid; Selenocysteine | 2019 |
Nutraceutical formulation, characterisation, and in-vitro evaluation of methylselenocysteine and selenocystine using food derived chitosan:zein nanoparticles.
Topics: Anticarcinogenic Agents; Antiviral Agents; Caco-2 Cells; Cell Survival; Chitosan; Cystine; Dietary Supplements; Gels; Hep G2 Cells; Humans; Microscopy, Electron, Scanning; Nanoparticles; Organoselenium Compounds; Particle Size; Polyphosphates; Selenocysteine; Zein | 2019 |
Synthesis of alpha-methyl selenocysteine and its utilization as a glutathione peroxidase mimic.
Topics: Animals; Glutathione Peroxidase; Humans; Peptides; Protein Stability; Selenocysteine; Solid-Phase Synthesis Techniques | 2019 |
Selenium biofortification and its effect on multi-element change in Auricularia auricular.
Topics: Basidiomycota; Biofortification; Chromium; Copper; Cystine; Fruiting Bodies, Fungal; Fungal Proteins; Humans; Iron; Nutritive Value; Organoselenium Compounds; Selenic Acid; Selenious Acid; Selenium; Selenocysteine; Selenomethionine | 2019 |
Development and application of a HPLC-ICP-MS method to determine selenium speciation in muscle of pigs treated with different selenium supplements.
Topics: Animals; Chromatography, High Pressure Liquid; Cystine; Dietary Supplements; Food Analysis; Male; Mass Spectrometry; Muscle, Skeletal; Organoselenium Compounds; Reproducibility of Results; Selenious Acid; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; Swine; Urea | 2020 |
Se-methylselenocysteine stimulates migration and antioxidant response in HaCaT keratinocytes: Implications for wound healing.
Topics: Antioxidants; beta Catenin; Cadherins; Cell Line; Cell Movement; Cell Nucleus; Cell Proliferation; Down-Regulation; Epithelial-Mesenchymal Transition; Glycogen Synthase Kinase 3 beta; Humans; Keratinocytes; Matrix Metalloproteinases; NF-E2-Related Factor 2; Nuclear Proteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Selenocysteine; Snail Family Transcription Factors; Twist-Related Protein 1; Wound Healing | 2020 |
Distribution and chemical form of selenium in Neptunia amplexicaulis from Central Queensland, Australia.
Topics: Animals; Chromatography, Liquid; Fabaceae; Humans; Mass Spectrometry; Microscopy, Electron, Scanning; Plant Leaves; Plant Roots; Plant Stems; Queensland; Selenium; Selenocysteine; Selenomethionine; Species Specificity; X-Ray Absorption Spectroscopy | 2020 |
Effect of gut microflora on nutritional availability of selenium.
Topics: Animals; Cyanates; Gastrointestinal Microbiome; Male; Nutritive Value; Rats; Rats, Wistar; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine | 2020 |
Green and simple extraction of free seleno-amino acids from powdered and lyophilized milk samples with natural deep eutectic solvents.
Topics: Animals; Chemical Fractionation; Chromatography, Liquid; Female; Food Analysis; Food, Fortified; Freeze Drying; Green Chemistry Technology; Limit of Detection; Mass Spectrometry; Milk; Powders; Selenium; Selenocysteine; Selenomethionine; Sheep; Solvents | 2020 |
Selenium biofortification in Hericium erinaceus (Lion's Mane mushroom) and its in vitro bioaccessibility.
Topics: Basidiomycota; Biofortification; Biological Availability; Cystine; Digestion; Fruiting Bodies, Fungal; Humans; Organoselenium Compounds; Selenic Acid; Selenious Acid; Selenium; Selenocysteine; Selenomethionine | 2020 |
The Effect of Methylselenocysteine and Sodium Selenite Treatment on microRNA Expression in Liver Cancer Cell Lines.
Topics: Anticarcinogenic Agents; Apoptosis; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Proliferation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; MicroRNAs; Selenocysteine; Sodium Selenite; Trace Elements; Tumor Cells, Cultured | 2020 |
Can Selenoenzymes Resist Electrophilic Modification? Evidence from Thioredoxin Reductase and a Mutant Containing α-Methylselenocysteine.
Topics: Cysteine; Humans; Mutation; Oxidation-Reduction; Selenium Oxides; Selenocysteine; Selenoproteins; Thioredoxin-Disulfide Reductase; Thioredoxins | 2020 |
Suppression of lipopolysaccharide-induced activation of RAW 264.7 macrophages by Se-methylseleno-l-cysteine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Cell Survival; Cysteine; Gene Expression Regulation; Lipopolysaccharides; Macrophage Activation; Mice; Molecular Structure; RAW 264.7 Cells; RNA, Messenger; Selenocysteine | 2020 |
Protective Effect of Se-Methylselenocysteine on Elaidic Acid-Induced Inflammation in Human Arterial Endothelial Cells.
Topics: Endothelial Cells; Humans; Inflammation; Oleic Acids; Selenocysteine | 2020 |
Se-Methylselenocysteine (SMC) Improves Cognitive Deficits by Attenuating Synaptic and Metabolic Abnormalities in Alzheimer's Mice Model: A Proteomic Study.
Topics: Alzheimer Disease; Animals; Cognition; Disease Models, Animal; Mice; Mice, Transgenic; Proteomics; Selenium; Selenocysteine | 2021 |
L-Se-methylselenocysteine sensitizes lung carcinoma to chemotherapy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Carriers; Female; Humans; Hydrogels; Lipid Peroxidation; Lung Neoplasms; Mice; Mice, Nude; Reactive Oxygen Species; Selenocysteine; Xenograft Model Antitumor Assays | 2021 |
Se-Methylselenocysteine Alleviates Liver Injury in Diethylnitrosamine (DEN)-Induced Hepatocellular Carcinoma Rat Model by Reducing Liver Enzymes, Inhibiting Angiogenesis, and Suppressing Nitric Oxide (NO)/Nitric Oxide Synthase (NOS) Signaling Pathway.
Topics: Alanine Transaminase; Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Aspartate Aminotransferases; Carcinogenesis; Carcinoma, Hepatocellular; Cell Proliferation; Disease Models, Animal; gamma-Glutamyltransferase; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Nitric Oxide Synthase; Rats; Selenocysteine; Treatment Outcome | 2021 |
Sex-dimorphic distribution and anti-oxidative effects of selenomethionine and Se-methylselenocysteine supplementation.
Topics: Animals; Antioxidants; Dietary Supplements; Female; Hydrogen Peroxide; Male; Rats; Rats, Sprague-Dawley; Selenium; Selenocysteine; Selenomethionine | 2021 |
In vitro cytotoxic data on Se-methylselenocysteine conjugated to dendritic poly(glycerol) against human squamous carcinoma cells.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Glycerol; Head and Neck Neoplasms; Humans; Selenium; Selenocysteine; Squamous Cell Carcinoma of Head and Neck | 2022 |
Application of alpha-methyl selenocysteine as a tool for the study of selenoproteins.
Topics: Animals; Mammals; Oxidation-Reduction; Selenium; Selenocysteine; Selenoproteins; Solid-Phase Synthesis Techniques | 2022 |
Methylselenocysteine Potentiates Etoposide-Induced Cytotoxicity by Enhancing Gap Junction Activity.
Topics: Connexins; Etoposide; Gap Junctions; HeLa Cells; Humans; Selenocysteine | 2022 |
L-Se-methylselenocysteine loaded mucoadhesive thermogel for effective treatment of Vulvar candidiasis.
Topics: Animals; Antifungal Agents; Candida; Candida albicans; Candidiasis, Vulvovaginal; Female; Humans; Rats; Selenocysteine | 2022 |
Implication of methylselenocysteine in combination chemotherapy with gemcitabine for improved anticancer efficacy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Deoxycytidine; Gemcitabine; Selenocysteine | 2022 |
Enhanced selenocysteine biosynthesis for seleno-methylselenocysteine production in Bacillus subtilis.
Topics: Bacillus subtilis; Metabolic Engineering; Methionine Adenosyltransferase; S-Adenosylmethionine; Selenocysteine; Serine O-Acetyltransferase | 2023 |
Optimized methyl donor and reduced precursor degradation pathway for seleno-methylselenocysteine production in Bacillus subtilis.
Topics: Bacillus subtilis; Cysteine; Selenium; Selenocysteine; Vitamin U | 2023 |
Characteristics of selenazolidine prodrugs of selenocysteine: toxicity and glutathione peroxidase induction in V79 cells.
Topics: Animals; Cricetinae; Cricetulus; Enzyme Induction; Glutathione Peroxidase; Organoselenium Compounds; Prodrugs; Proline; Selenocysteine; Stereoisomerism; Structure-Activity Relationship | 2003 |