selenocysteine has been researched along with cysteine in 334 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 63 (18.86) | 18.7374 |
| 1990's | 58 (17.37) | 18.2507 |
| 2000's | 113 (33.83) | 29.6817 |
| 2010's | 78 (23.35) | 24.3611 |
| 2020's | 22 (6.59) | 2.80 |
| Authors | Studies |
|---|---|
| Hall, L; Jackson, RM; Jones, R; Niang, LS; Perry, AC | 1 |
| Berry, MJ; Harney, JW; Kieffer, JD; Larsen, PR; Maia, AL | 1 |
| Böck, A; Heider, J | 1 |
| Axley, MJ; Chen, GT; Hacia, J; Inouye, M | 1 |
| Berry, MJ; Larsen, PR | 1 |
| Ganther, HE; Ip, C | 2 |
| Bannai, S; Ishii, T; Kohno, H; Taketani, S; Tokunaga, R | 1 |
| Bénicourt, C; Faucheu, C; Hervé, F; Lalanne, JL; Rocher, C | 1 |
| Baron, C; Böck, A; Heider, J | 1 |
| Falvey, D; Frenkel, GD; MacVicar, C | 1 |
| Boylan, LM; Spallholz, JE; Yan, L; Yee, JA | 1 |
| Ganther, HE; Ip, C; Thompson, HJ | 2 |
| Budnick, RM; Ganther, HE; Hayes, C; Ip, C | 1 |
| Banu, L; Berry, MJ; Larsen, PR | 1 |
| Garcia, GE; Stadtman, TC | 2 |
| Caffrey, PB; Frenkel, GD | 1 |
| Esaki, N; Oikawa, T; Soda, K; Tanaka, H | 1 |
| Böck, A; Forchhammer, K; Heider, J; Leinfelder, W; Sawers, G; Veprek, B; Zinoni, F | 1 |
| Berry, MJ; Kieffer, JD; Larsen, PR | 1 |
| Böck, A; Ching, WM; Davis, JN; Stadtman, TC; Zinoni, F | 1 |
| Burk, RF | 2 |
| Berry, MJ; Harney, JW; Kieffer, JD; Larsen, PR | 1 |
| Stadtman, TC | 4 |
| Banu, L; Berry, MJ; Chen, YY; Harney, JW; Kieffer, JD; Larsen, PR; Mandel, SJ | 1 |
| Berg, BL; Heider, J; Li, J; Stewart, V | 1 |
| Baron, C; Berg, BL; Stewart, V | 1 |
| Hatfield, DL; Lee, BJ; Price, NM; Stadtman, TC | 1 |
| Böck, A; Forchhammer, K | 1 |
| Baron, C; Böck, A; Forchhammer, K; Heider, J | 1 |
| Böck, A; Boesmiller, K; Forchhammer, K | 1 |
| Hatfield, D; Jacobson, KB; Kim, YS; Lee, BJ; Rajagopalan, M; You, KH | 1 |
| Böck, A; Forchhammer, K; Rücknagel, KP | 1 |
| Böck, A; Heider, J; Zinoni, F | 1 |
| Politino, M; Stadtman, TC; Tsai, L; Veres, Z | 1 |
| Jukes, TH | 1 |
| Motchnik, PA; Tappel, AL | 1 |
| Ames, BN; Kramer, GF | 1 |
| Böck, A; Heider, J; Leinfelder, W | 1 |
| DerVartanian, DV; Eidsness, MK; Legall, J; Moura, I; Moura, JJ; Peck, HD; Prickril, BC; Scott, RA | 1 |
| Hatfield, D; Kang, SG; Lee, BJ | 1 |
| Böck, A; Leinfelder, W; Stadtman, TC | 1 |
| Mizutani, T | 1 |
| Böck, A; Ott, G; Schön, A; Söll, D; Sprinzl, M | 1 |
| Böck, A; Forchhammer, K; Leinfelder, W | 1 |
| Axley, MJ; Stadtman, TC | 1 |
| Esaki, N; Soda, K; Tanaka, H | 1 |
| Birkmann, A; Böck, A; Stadtman, TC; Zinoni, F | 1 |
| Danielson, KG; Medina, D | 1 |
| Beilstein, MA; Whanger, PD | 1 |
| Evenson, JK; Sunde, RA | 1 |
| Beilstein, MA; Butler, JA; Deagen, JT; Whanger, PD | 1 |
| Sliwkowski, MX; Stadtman, TC | 2 |
| Bell, GI; Hallewell, RA; Irvine, BD; Mullenbach, GT; Tabrizi, A | 1 |
| Esaki, N; Soda, K | 1 |
| Soda, K; Tanaka, H | 1 |
| Böck, A; Forchhammer, K; Leinfelder, W; Mandrand-Berthelot, MA; Sawers, G; Zinoni, F | 1 |
| Söll, D | 1 |
| Böck, A; Leinfelder, W; Mandrand-Berthelot, MA; Zehelein, E | 1 |
| Hitaka, T; Mizutani, T | 2 |
| Blarzino, C; Cini, C; Coccia, R; Foppoli, C | 1 |
| Bell, GI; Hallewell, RA; Irvine, BD; Mullenbach, GT; Tabrizi, A; Tainer, JA | 1 |
| Esaki, K; Soda, K; Tanaka, H | 1 |
| Engelberg-Kulka, H; Schoulaker-Schwarz, R | 1 |
| Böck, A; Stadtman, TC | 1 |
| Affara, N; Chambers, I; Frampton, J; Goldfarb, P; Harrison, PR; McBain, W | 1 |
| Birkmann, A; Böck, A; Leinfelder, W; Zinoni, F | 1 |
| Hawkes, WC; Tappel, AL; Wilhelmsen, EC | 1 |
| Esaki, N; Karai, N; Nakamura, T; Soda, K; Tanaka, H | 1 |
| Chow, CM; McConnell, WB; Nigam, SN | 1 |
| Yamazaki, S | 1 |
| Motsenbocker, MA; Tappel, AL | 3 |
| Condell, RA; Tappel, AL | 1 |
| Hawkes, WC; Tappel, AL | 1 |
| Chocat, P; Esaki, N; Nakamura, T; Soda, K; Tanaka, H | 1 |
| Chaudiere, J; Tappel, AL | 1 |
| Foster, SJ; Ganther, HE; Kraus, RJ | 2 |
| Chocat, P; Esaki, N; Karai, N; Nakamura, T; Soda, K; Tanaka, H | 1 |
| Esaki, N; Karai, N; Soda, K; Tanaka, H | 1 |
| Combs, GF; Combs, SB | 1 |
| Tappel, AL | 1 |
| Hawkes, WC; Motsenbocker, MA; Tappel, AL; Wilhelmsen, EC | 1 |
| Burnell, JN; Karle, JA; Shrift, A | 1 |
| Jao, TC; Lopez, J; Rudzinski, WE | 1 |
| Esaki, N; Morino, Y; Nakamura, T; Soda, K; Suzuki, T; Tanaka, H | 1 |
| Beilstein, MA; Tripp, MJ; Whanger, PD | 1 |
| Esaki, N; Nakamura, T; Soda, K; Tanaka, H | 1 |
| Foster, SJ; Ganther, HE | 1 |
| Ganther, H; Ip, C; Jiang, C; Kaeck, M; Lu, J; Thompson, H; Vadhanavikit, S | 1 |
| Axley, MJ; Gladyshev, VN; Khangulov, SV; Stadtman, TC | 1 |
| Baron, C; Böck, A; Gsell, B; Müller, S; Senn, H; Vetter, W | 1 |
| Ganther, H; Ip, C; Lisk, DJ; Lu, J; Pei, H; Thompson, HJ | 1 |
| Thauer, RK; Vaupel, M; Vorholt, JA | 1 |
| Medina, D; Sinha, R | 1 |
| Böck, A; Heider, J; Müller, S | 1 |
| Baines, IC; Kang, SW; Rhee, SG | 1 |
| Arnér, ES; Holmgren, A; Nordberg, J; Zhong, L | 1 |
| Guo, X; Wu, L | 1 |
| Ponting, CP; Schröder, E | 1 |
| Böck, A; Boschi-Muller, S; Branlant, G; Muller, S; Van Dorsselaer, A | 1 |
| Lacourciere, GM; Stadtman, TC | 1 |
| Böck, A; Neuhierl, B; Wang, Y | 1 |
| Carey, PR; Dinakarpandian, D; Hilvert, D; McRee, DE; McTigue, M; Shenoy, BC | 1 |
| Mutoh, N; Nakagawa, CW; Yamada, K | 1 |
| Ganther, HE | 1 |
| Esaki, N; Oikawa, T; Soda, K | 1 |
| Jaken, S; Kiley, SC; Lu, JX; Medina, D; Moraes, R; Sinha, R; Thompson, HJ | 1 |
| Bar-Noy, S; Kwon, J; Lee, SR; Levine, RL; Rhee, SG; Stadtman, TC | 1 |
| Arnér, ES; Holmgren, A; Zhong, L | 1 |
| Belduz, A; Flohé, L; Jaenecke, S; Kollmus, H; McCarthy, JE; Nasim, MT | 1 |
| Camoin, L; Eshdat, Y; Faltin, Z; Hazebrouck, S; Strosberg, AD | 1 |
| Holmgren, A; Persson, K; Sandalova, T; Schneider, G; Zhong, L | 1 |
| Matthews, RG; Smith, AE; Zhou, ZS | 1 |
| Ip, C; Polan, CE; Uden, PC; Welbaum, G; Whanger, PD | 1 |
| Aumann, KD; Becker, K; Brigelius-Flohé, R; Flohé, L; Gamain, B; Slomianny, C; Sztajer, H | 1 |
| Buettner, C; Harney, JW; Larsen, PR | 1 |
| Matthews, RG; Peariso, K; Penner-Hahn, JE; Smith, AE; Zhou, ZS | 1 |
| Commandeur, JN; Floor, GC; Rettie, AE; Rooseboom, M; Vermeulen, NP | 1 |
| Cho, DY; Chung, AS; Jung, U; Kim, T | 1 |
| Block, E; Dong, Y; Ip, C; Lisk, D | 1 |
| Fujii, J; Fujii, T; Fujiwara, N; Taniguchi, N | 1 |
| Chung, AS; Jung, U; Yoon, SO; Zheng, X | 1 |
| Ganther, HE; Singh, U; Sinha, R; Unni, E | 1 |
| Hall, MB; Niu, S | 1 |
| Commandeur, JN; Rooseboom, M; Vermeulen, NP | 1 |
| Ganther, H; Ip, C; Medina, D; Thompson, H | 1 |
| Reid, TW; Shriver, BJ; Spallholz, JE | 1 |
| Lima, CD | 1 |
| Klootwijk, W; Kuiper, GG; Visser, TJ | 2 |
| Gladyshev, VN; Kryukov, GV | 1 |
| Esaki, N; Fujii, T; Hata, Y; Kato, S; Kurihara, T; Mihara, H | 1 |
| Baek, WK; Cha, SD; Cho, CH; Cho, JW; Kim, SP; Kwon, TK; Park, JW; Suh, MH; Suh, SI; Yeo, JK | 1 |
| Commandeur, JN; Groot, EJ; Rooseboom, M; Vermeulen, NP | 1 |
| Commandeur, JN; Durgut, F; Rooseboom, M; Vermeulen, NP | 1 |
| Berry, MJ; Chung, M; Harney, JW; Klimovitsky, B; Mansell, JB; Zavacki, AM | 1 |
| Hilvert, D; Roelfes, G | 1 |
| Barras, F; Fontecave, M; Loiseau, L; Nachin, L; Ollagnier-de-Choudens, S | 1 |
| DI SOMMA, AA; JACOBS, AL; TRELEASE, SF | 1 |
| SHRIFT, A; VIRUPAKSHA, TK | 1 |
| Baek, WK; Choi, ES; Im, KJ; Jang, BC; Kim, SP; Kwon, TK; Park, JW; Suh, MH; Suh, SI | 1 |
| Giles, GI; Giles, NM; Jacob, C; Sies, H | 1 |
| Aumelas, A; Böck, A; Dumas, C; Hoh, F; Sanchez, JF; Strub, JM; Strub, MP | 1 |
| AbdelSamie, M; Böck, A; Caruso, J; Chiang, CY; deSouza, M; LeDuc, DL; Malit, MF; Meija, J; Montes-Bayon, M; Neuhierl, B; Tagmount, A; Tarun, AS; Terry, N; Wu, CP | 1 |
| Gladyshev, VN; Kim, HY | 2 |
| Albrecht, C; Brunk, DG; Ellis, DR; Harris, HH; Lahner, B; Orser, C; Pickering, IJ; Salt, DE; Sors, TG; Wood, KV | 1 |
| Buzin, Y; Carrasco, N; Halpert, E; Huang, Z; Tyson, E | 1 |
| Palace, VP; Reid, TW; Spallholz, JE | 1 |
| Cao, S; Durrani, FA; Rustum, YM | 1 |
| Cho, SH; Choi, CY; Kim, BH; Kim, JH; Kim, JR; Kim, YD; Kwon, J; Lee, SM; Lee, SR | 1 |
| Block, E; Boakye, HT; Glass, RS; Jacobsen, NE; Johnson, S; Kahakachchi, C; Kamiński, R; Skowrońska, A; Tyson, JF; Uden, PC | 1 |
| Azrak, RG; Cao, S; Durrani, FA; Frank, C; Li, ZR; Rustum, YM; Yin, MB | 1 |
| Kittrell, FS; Singh, U; Sinha, R; Unni, E | 1 |
| Booker, SJ; Iwig, DF | 1 |
| Bittner, F; Heidenreich, T; Mendel, RR; Wollers, S | 1 |
| Bi, SL; Chen, Q; Fang, Q; Lin, C; Ning, L; Yang, JG; Yi, Y; Zha, YY; Zheng, YH | 1 |
| Heller, LI; Kochian, LV; Li, L; Lyi, SM; Rutzke, M; Welch, RM | 1 |
| Fang, J; Holmgren, A; Lu, J | 1 |
| Azrak, RG; Cao, S; Durrani, FA; Li, X; McLeod, HL; Pendyala, L; Rustum, YM; Shannon, WD; Smith, PF; Yu, J | 1 |
| Cao, S; Durrani, FA; Fakih, M; Rustum, YM | 1 |
| Koul, D; Sinha, R; Unni, E; Yung, WK | 1 |
| Su, M; Tian, DP; Wu, XY; Zhang, G | 1 |
| Abdulah, R; Koyama, H; Miyazaki, K; Nakazawa, M | 1 |
| Fang, J; Holmgren, A | 1 |
| Azrak, RG; Bhattacharya, A; Cao, S; Durrani, FA; Frank, C; Hapke, G; Li, ZR; Rustum, YM; Tóth, K; Yin, MB | 1 |
| Dong, Y; Gao, AC; Ip, C; Lee, SO; Nadiminty, N; Trump, DL; Yeon Chun, J | 1 |
| Kim, YH; Kwon, TK; Lee, TJ; Min, do S; Park, JW | 1 |
| Burchfiel, J; Butler, JA; Forsberg, NE; Liang, YC; Ou, BR; Whanger, PD; Yeh, JY | 1 |
| Flemer, S; Harris, KM; Hondal, RJ | 1 |
| Azrak, RG; Foster, BA; Frank, CL; Li, F; Ling, X; Rustum, YM; Slocum, HK | 1 |
| Gladyshev, VN; Romero, H; Salinas, G; Zhang, Y | 1 |
| Doi, C; Suzuki, KT; Suzuki, N | 1 |
| Fakra, S; Freeman, JL; Marcus, MA; Pilon-Smits, EA; Quinn, CF | 1 |
| Adair, BM; Fomenko, DE; Gladyshev, VN; Thomas, DJ; Xing, W | 1 |
| Azrak, RG; Cao, S; Combs, GF; Durrani, FA; Fakih, M; Pendyala, L; Prey, J; Rustum, YM; Smith, PF | 1 |
| Cardey, B; Enescu, M | 1 |
| Eckenroth, BE; Everse, SJ; Hondal, RJ; Rould, MA | 1 |
| Fakra, S; Freeman, JL; Lindblom, SD; Marcus, MA; Pilon-Smits, EAH; Quinn, CF | 1 |
| Wang, X; Xu, T; Zhang, J | 1 |
| Brandt, W; Schneider, A; Wessjohann, LA | 1 |
| Bravo, L; Cámara, C; Cuello, S; Goya, L; Madrid, Y; Martín, MA; Mateos, R; Ramos, S | 1 |
| Ohta, Y; Suzuki, KT; Suzuki, N; Tsuji, Y | 1 |
| Crowell, JA; Johnson, WD; Kapetanovic, I; McCormick, DL; Morrissey, RL | 1 |
| Devine, KM; Hohn, MJ; Jester, B; Sheppard, K; Söll, D; Yuan, J | 1 |
| Jiao, NL; Wang, J; Zheng, J | 1 |
| Iwaoka, M; Nakazato, T; Oishi, S; Ooka, R; Yoshida, S | 1 |
| Gladyshev, VN; Hatfield, DL; Lobanov, AV | 1 |
| Elliott, RM; Fairweather-Tait, SJ; Goldson, AJ; Hurst, R | 1 |
| Gangapurkar, B; Jariwalla, RJ; Nakamura, D | 1 |
| Bhattacharya, A; Oven, SD; Rustum, YM; Seshadri, M; Tóth, K; Vaughan, MM | 1 |
| Bhattacharya, A; Cao, S; Chintala, S; Durrani, FA; Rustum, YM; Slocum, HK; Tóth, K | 1 |
| Chung, AS; Jung, JY; Kim, A; Lee, SH; Lim, JS; Son, M | 1 |
| Kim, HY; Lee, TH | 1 |
| Baker, MV; Barnard, PJ; Berners-Price, SJ; Filipovska, A; Hickey, JL; Ruhayel, RA | 1 |
| Hohn, MJ; O'Donoghue, P; Palioura, S; Sherrer, RL; Söll, D; Su, D; Yuan, J | 1 |
| Alberto, EE; Braga, AL; Cordeiro, AT; Magalhães, A; Rodrigues, EM; Sculaccio, SA; Thiemann, OH | 1 |
| Belame, A; Burow, ME; Carrier, L; Li, Z; Rowan, BG; Salvo, VA; Thiyagarajah, A | 1 |
| Mahn, AV; Ruz, M; Toledo, HM | 1 |
| Barry, AN; Blackburn, NJ; Clark, KM; Otoikhian, A; van der Donk, WA | 1 |
| Baranska, A; Bryla, J; Dudziak, M; Hapka, M; Kiersztan, A; Lebiedzinska, M; Winiarska, K | 1 |
| Blankenberg, S; Handy, DE; Lackner, KJ; Loscalzo, J; Lubos, E; Messow, CM; Munzel, T; Peetz, D; Schnabel, R; Sinning, CR; Wild, PS; Zeller, T | 1 |
| Brummell, DA; Hunter, DA; Joyce, NI; Matich, AJ; McKenzie, MJ; Pathirana, R; Rowan, DD; Watson, LM | 1 |
| Duan, J; Hu, B | 1 |
| Zarbl, H; Zhang, X | 1 |
| Fomenko, DE; Gladyshev, VN; Hatfield, DL; Klobutcher, LA; Lobanov, AV; Morrison, HG; Sogin, ML; Turanov, AA | 1 |
| Bulaj, G; Olivera, BM; Skalicky, JJ; Walewska, A; Yoshikami, D; Zhang, MM | 1 |
| Ogra, Y; Suzuki, N; T Suzuki, K; Tsuji, Y | 1 |
| Burk, RF; Hill, KE; Holmgren, A; Lönn, ME; Lu, J; Zhong, L | 1 |
| Kwon, TK; Lee, JT; Lee, TJ; Park, JW | 1 |
| Hondal, RJ; Schroll, AL | 1 |
| Bonorden, MJ; Cleary, MP; Hu, H; Lee, HJ; Li, GX; Liao, JD; Lü, J; Wang, L; Zhang, Y | 1 |
| Cervinka, M; Hasková, P; Králová, V; Rudolf, E; Schröterová, L; Vorácová, A | 1 |
| Clark, KM; Lu, Y; van der Donk, WA | 1 |
| Bhattacharya, A; Cao, S; Durrani, FA; Faber, E; Repasky, EA; Rustum, YM; Sen, A; Seshadri, M; Tóth, K | 1 |
| Hirano, S; Kobayashi, Y; Konishi, S; Ohta, Y | 1 |
| Mahn, AV; Ruz, MH; Toledo, HM | 1 |
| Ahmad, A; Jain, VK; Kumar, BS; Kumbhare, LB; Kunwar, A; Priyadarsini, KI | 1 |
| Amoako, PO; Tyson, JF; Uden, PC | 1 |
| Dempsey, S; Jack, C; Miller, CH; Nisa, S; O'Toole, R | 1 |
| Echigo, S; Endo, M; Rikiishi, H; Shinohara, F; Suzuki, M | 1 |
| Esaki, N; Imai, T; Kurihara, T; Mihara, H | 1 |
| Cao, S; Chintala, S; Durrani, FA; Jensen, RL; Rustum, YM; Tóth, K; Vaughan, MM | 1 |
| Li, S; Manning, E; Mathew, J; Pham, S; Ruiz, P; Salgar, SK; Vazquez-Padron, RI | 1 |
| Cheng, WH; Kang, MM; Schoene, NW; Wu, M | 1 |
| Arnér, ES | 1 |
| Fang, MZ; Zarbl, H; Zhang, X | 1 |
| Ahmad, A; Kumar, BS; Kunwar, A; Priyadarsini, KI; Singh, BG | 1 |
| Canene-Adams, K; Diamond, AM; Erdman, JW; Ford, NA; Lindshield, BL; Wallig, MA | 1 |
| Alewood, PF; de Araujo, AD; Feytens, D; Muttenthaler, M; Ramos, YG | 1 |
| Begaye, A; Ross, S; Uthus, E; Zeng, H | 1 |
| Anderson, LB; Lü, J; Wang, L; Witthuhn, B; Xu, Y; Zhang, J | 1 |
| Cozza, G; Flohé, L; Toppo, S; Ursini, F | 1 |
| Dong, Y; Gao, L; Gao, R; Liu, X; Zhang, H; Zhao, L; Zhao, X; Zhao, Y | 1 |
| Cheng, WH; Lartey, FM; Qi, Y; Schoene, NW | 1 |
| Dawson, PE; Keinan, E; Metanis, N | 1 |
| García-Barrera, T; Gómez-Ariza, JL; Moreno, F | 1 |
| Bennett, LE; Cappa, JJ; Fakra, SC; Freeman, JL; Lindblom, SD; Marcus, MA; Pilon-Smits, EA; Quinn, CF; Quinn, EK; Reynolds, RJ | 1 |
| Arnér, ES; Carvalho, CM; Holmgren, A; Lu, J; Zhang, X | 1 |
| Carlson, BA; Everley, RA; Gladyshev, VN; Gygi, SP; Hatfield, DL; Nandakumar, R; Sorokina, I; Turanov, AA; Xu, XM; Yoo, MH | 1 |
| Cheng, WH; Combs, GF; Jackson, MI; Zeng, H | 1 |
| Badmaev, V; Chen, WJ; Ho, CT; Hong, HM; Jhang, AZ; Lin, CL; Nagabhushanam, K; Pan, MH; Tsai, JH | 1 |
| Aitken, JB; de Jonge, MD; Finney, LA; Harris, HH; Howard, DL; Musgrave, IF; Paterson, DJ; Vogt, S; Weekley, CM | 1 |
| Bhabak, KP; Bhuyan, BJ; Mugesh, G | 1 |
| Cleary, MP; Liao, JD; Lü, J; Nkhata, K; Quealy, E; Wang, L; Zhang, J; Zhang, Y | 1 |
| Bhattacharya, A; Hoffman, RM; Rajput, A; Rustum, YM; San Martin, ID; Seshadri, M; Turowski, SG | 1 |
| Inagaki, K; Kawamura, K; Kuwahara, M; Tamura, T | 1 |
| Hillestrøm, PR; Kápolna, E; Larsen, EH; Mapelli, V; Olsson, L | 1 |
| Bosello, V; Conrad, M; Maiorino, M; Mannes, AM; Seiler, A | 1 |
| Liu, X; Pietsch, KE; Sturla, SJ | 1 |
| Bhattacharya, A | 1 |
| Bernhard, EJ | 1 |
| Anderson, LB; Li, G; Lü, J; Wang, L; Witthuhn, B; Xu, Y; Zhang, J | 1 |
| Cuderman, P; Germ, M; Mechora, S; Stibilj, V | 1 |
| Bergan, R; Coomes, M; Crowell, J; Davis, W; Dew, A; Fakih, M; Fetterly, G; French-Christy, R; Ip, C; Jovanovic, B; Marshall, JR; Perloff, M; Romano, K | 1 |
| Azrak, RG; Bhattacharya, A; Cao, S; Durrani, FA; Rustum, YM; Toth, K | 1 |
| Holmgren, A; Sengupta, R | 1 |
| Brummell, DA; Hunter, DA; Joyce, NI; McKenzie, MJ; Pathirana, R; Watson, LM; West, PJ | 1 |
| Herodes, K; Leito, I; Rebane, R | 1 |
| Angelucci, F; Bellelli, A; Boumis, G; Brunori, M; Miele, AE; Saccoccia, F; Williams, DL | 1 |
| Aitken, JB; Harris, HH; Musgrave, IF; Weekley, CM | 1 |
| Antoch, MP; Chernov, MV; Comas-Soberats, M; Fedtsova, N; Gleiberman, AS; Gudkov, AV; Hu, Y; Jackson, M; Kuropatwinski, KK; Rustum, YM; Spengler, ML | 1 |
| Carlson, BA; Gladyshev, VN; Hatfield, DL; Turanov, AA; Xu, XM; Yoo, MH | 1 |
| Antar, HA; Moustafa, ME | 1 |
| Lees, WJ | 1 |
| Blais, KD; Bulaj, G; Elmslie, KS; Gowd, KH; Olivera, BM; Steiner, AM | 1 |
| Arnér, ES; Peng, X; Xu, J | 1 |
| Craik, DJ | 1 |
| Bahnson, BJ; Dong, M; Rozovsky, S; Rubenstein, RP; Schaefer, SA; Thorpe, C; Wilkie, WA | 1 |
| Bent, AF; Botting, CH; Fuszard, MA; Houssen, WE; Jaspars, M; Koehnke, J; Morawitz, F; Naismith, JH; Shirran, SL; Smellie, IA; Smith, MC | 1 |
| Chandler, JD; Day, BJ; Hondal, RJ; Nichols, DP; Nick, JA | 1 |
| Haumann, M; Hille, R; Leimkühler, S; Niks, D; Rajagopalan, KV; Reschke, S; Sigfridsson, KG; Wilson, H | 1 |
| Ankonina, G; Brif, A; Drathen, C; Pokroy, B | 1 |
| Chen, JM; Cole, ST; Hartmann, P; Kolly, GS; Marienhagen, J; Pojer, F; Rybniker, J; van Gumpel, E | 1 |
| Cunniff, B; Fredette, N; Heintz, NH; Hondal, RJ; Snider, GW; Stumpff, J | 1 |
| Chen, L; Guo, X; Song, J; Wang, S; Wei, J; Yang, X; Yu, Y | 1 |
| Flemer, S | 1 |
| Grassi, G; Koppenol, WH; Nauser, T; Steinmann, D | 1 |
| Alkazemi, MH; Englert, M; Haruna, K; Liu, Y; Söll, D | 1 |
| Alcutt, S; Artigues, A; Cooper, AJ; Dorai, T; Jones, ME; Krasnikov, BF; Li, J; Pinto, JT; Villar, MT | 1 |
| Amara, SG; Divito, CB; Torres-Salazar, D; Watts, SD | 1 |
| Angelucci, F; Bellelli, A; Boumis, G; Desiato, G; Miele, AE; Saccoccia, F | 1 |
| Agouridas, V; Melnyk, O | 1 |
| Bubenik, JL; Driscoll, DM; Miniard, AC | 1 |
| Kodadek, T; Li, X; Patterson, JT; Pedzisa, L; Rader, C; Roush, WR; Sarkar, M | 1 |
| Malins, LR; McGowan, S; Mitchell, NJ; Payne, RJ | 1 |
| Everley, RA; Gladyshev, VN; Gygi, SP; Hatfield, DL; Hybsier, S; Renko, K; Schomburg, L; Turanov, AA | 1 |
| Arnér, ES; Cheng, Q; Xu, J | 1 |
| Arnér, ESJ; Benhar, M; Engelman, R; Ziv, T | 1 |
| Hondal, RJ; Ruggles, EL; Ste Marie, EJ | 1 |
| Capacho, AS; Machuqueiro, M; Teixeira, VH | 1 |
| Janowski, R; Madl, T; Niessing, D; Scanu, S | 1 |
| Englert, M; Merkuryev, A; Mukai, T; Söll, D; Vargas-Rodriguez, O | 1 |
| Al-Soodani, AT; Buck-Koehntop, BA; Thomas, GC; Wang, S; Woycechowsky, KJ | 1 |
| Moore, TW; Skowron, KJ; Speltz, TE | 1 |
| Ajmo, JM; Bahia, PK; Hadley, SH; Stanford, KR; Taylor-Clark, TE | 1 |
| Lansky, S; Metanis, N; Rege, N; Shalev, DE; Shoham, G; Weil-Ktorza, O; Weiss, MA | 1 |
| Jang, JK; Jin, Y; Kang, H; Kim, IY; Ko, KY; Lee, JH | 1 |
| Alwan, KB; Blackburn, NJ; Britt, RD; Rao, G | 1 |
| Bickelhaupt, FM; Dalla Tiezza, M; Flohé, L; Maiorino, M; Orian, L; Ursini, F | 1 |
| Haupt, DJ; Hondal, RJ; Masterson, DS; Previs, MJ; Ste Marie, EJ; van der Vliet, A; Wehrle, RJ; Wood, NB | 1 |
| Brenner, V; Donon, J; Gloaguen, E; Goldsztejn, G; Mons, M; Mundlapati, VR; Tardivel, B | 1 |
| Wang, G; Wu, H; Zhan, Q | 1 |
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| Coletti, C; La Mendola, D; Marrone, A; Marzo, T; Re, N; Storchi, L; Tolbatov, I | 1 |
| Han, F; Huang, Z; Liu, Y; Wang, Q; Wu, H; Zhan, S | 1 |
| Chung, CZ; Crnković, A; Krahn, N; Söll, D | 1 |
| Bailey, CA; Cáceres, JC; Greene, BL; Yokoyama, K | 1 |
| Peeler, JC; Weerapana, E | 1 |
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| Blanco, M; Jiménez-Osés, G; Mazo, N; Navo, CD; Oroz, P; Peregrina, JM | 1 |
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| Hojo, H; Moroder, L; Okumura, N; Takao, T; Takei, T; Tanaka, H | 1 |
| Estrin, DA; Messias, A; Pedron, FN; Roitberg, AE; Zeida, A | 1 |
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34 review(s) available for selenocysteine and cysteine
| Article | Year |
|---|---|
The role of selenium in thyroid hormone action.
Topics: Animals; Cloning, Molecular; Congenital Hypothyroidism; Cysteine; Humans; Iodide Peroxidase; Organoselenium Compounds; Protein Biosynthesis; Selenium; Selenocysteine; Thyroid Hormones | 1992 |
Selenocysteine: the 21st amino acid.
Topics: Bacterial Proteins; Base Sequence; Biological Evolution; Codon; Cysteine; Molecular Sequence Data; RNA, Transfer; Selenium; Selenocysteine | 1991 |
Molecular biology of selenium with implications for its metabolism.
Topics: Animals; Cysteine; Proteins; Selenium; Selenocysteine; Selenoprotein P; Selenoproteins | 1991 |
Biosynthesis and function of selenocysteine-containing enzymes.
Topics: Animals; Cysteine; Enzymes; Proteins; Selenium; Selenocysteine; Selenoproteins | 1991 |
[Biology and biochemistry of selenium].
Topics: Animals; Biological Evolution; Cysteine; Escherichia coli; Humans; Organoselenium Compounds; Protein Biosynthesis; Proteins; RNA, Messenger; Selenium; Selenocysteine; Selenoproteins | 1991 |
Selenoprotein synthesis: an expansion of the genetic code.
Topics: Animals; Base Sequence; Codon; Cysteine; Escherichia coli; Genetic Code; Humans; Molecular Sequence Data; Organoselenium Compounds; Protein Biosynthesis; Proteins; RNA, Messenger; RNA, Transfer, Amino Acid-Specific; Selenium; Selenocysteine; Selenoproteins | 1991 |
Selenium biochemistry.
Topics: Animals; Bacteria; Cysteine; Glutathione Peroxidase; Oxidoreductases; Proteins; RNA, Transfer; Selenium; Selenocysteine; Selenoproteins | 1990 |
Genetic code 1990. Outlook.
Topics: Anaerobiosis; Anticodon; Base Sequence; Biological Evolution; Codon; Cysteine; DNA, Mitochondrial; Formate Dehydrogenases; Genetic Code; Molecular Sequence Data; Mutation; Peptide Chain Termination, Translational; Protein Biosynthesis; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Transfer; Selenium; Selenocysteine | 1990 |
Specific occurrence of selenium in enzymes and amino acid tRNAs.
Topics: Animals; Cysteine; Enzymes; RNA, Bacterial; RNA, Transfer, Amino Acid-Specific; Selenium; Selenocysteine | 1987 |
A flexible genetic code, or why does selenocysteine have no unique codon?
Topics: Anaerobiosis; Codon; Cysteine; Escherichia coli; Genetic Code; Peptide Chain Elongation, Translational; Selenium; Selenocysteine | 1988 |
Position and function of the organic selenium in glutathione peroxidase.
Topics: Amino Acid Sequence; Animals; Cattle; Chemical Phenomena; Chemistry; Cysteine; Erythrocytes; Glutathione Peroxidase; Humans; Mass Spectrometry; Selenium; Selenocysteine; Sheep; X-Ray Diffraction | 1984 |
Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Cycle Proteins; Cell Division; Cysteine; Enzyme Inhibitors; Gene Expression Regulation; Humans; Methylation; Mice; Molecular Weight; Neoplasms; Neoplasms, Experimental; Oxidation-Reduction; Protein Kinase C; Proteins; Selenium; Selenocysteine; Selenoproteins; Thioredoxin-Disulfide Reductase; Thioredoxins; Transcription Factors | 1999 |
Vitamin B6 enzymes participating in selenium amino acid metabolism.
Topics: Animals; Bacteria; Carbon-Sulfur Lyases; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Lyases; Mammals; Models, Chemical; Organoselenium Compounds; Pyridoxine; Selenocysteine | 1999 |
Chemistry and biological activity of novel selenium-containing compounds.
Topics: Animals; Anticarcinogenic Agents; Cysteine; Humans; Kidney Neoplasms; Molecular Weight; Organoselenium Compounds; Prodrugs; Selenium Compounds; Selenocysteine | 2001 |
Se-methylselenocysteine: a new compound for chemoprevention of breast cancer.
Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Cysteine; Disease Models, Animal; Female; Humans; Mammary Neoplasms, Experimental; Organoselenium Compounds; Selenocysteine; Treatment Outcome | 2001 |
Sulfur and selenium: the role of oxidation state in protein structure and function.
Topics: Cysteine; Endopeptidases; Free Radicals; Humans; Ligands; Methionine; Oxidation-Reduction; Oxidoreductases; Proteins; Selenium; Selenocysteine; Selenomethionine; Sulfhydryl Compounds; Sulfinic Acids; Sulfoxides; Sulfur | 2003 |
Selenium protects against toxicity induced by anticancer drugs and augments antitumor activity: a highly selective, new, and novel approach for the treatment of solid tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cysteine; Drug Synergism; Humans; Irinotecan; Mice; Neoplasms; Organoselenium Compounds; Rats; Selenocysteine; Selenomethionine | 2005 |
Chemical forms of selenium for cancer prevention.
Topics: Anticarcinogenic Agents; Chromatography; Chromatography, High Pressure Liquid; Cysteine; Food; Glutathione Peroxidase; Humans; Iodide Peroxidase; Mass Spectrometry; Methionine Sulfoxide Reductases; Models, Chemical; Neoplasms; Organoselenium Compounds; Selenium; Selenocysteine; Selenoprotein P; Selenoprotein W; Thioredoxin-Disulfide Reductase | 2005 |
From one amino acid to another: tRNA-dependent amino acid biosynthesis.
Topics: Amino Acyl-tRNA Synthetases; Asparagine; Cysteine; Glutamine; Nitrogenous Group Transferases; Phosphotransferases; RNA, Transfer, Amino Acyl; Selenocysteine | 2008 |
Synthesis of selenocysteine and selenomethionine derivatives from sulfur-containing amino acids.
Topics: Cysteine; Methionine; Peptides; Selenocysteine; Selenomethionine | 2008 |
How an obscure archaeal gene inspired the discovery of selenocysteine biosynthesis in humans.
Topics: Archaea; Cysteine; Evolution, Molecular; Genetic Code; Genetics; History, 20th Century; History, 21st Century; Humans; Selenocysteine | 2009 |
Selenoproteins-What unique properties can arise with selenocysteine in place of cysteine?
Topics: Animals; Cysteine; Humans; Selenocysteine; Selenoproteins | 2010 |
A comparison of thiol peroxidase mechanisms.
Topics: Catalysis; Catalytic Domain; Cysteine; Glutathione Peroxidase; Hydrogen Peroxide; Oxidation-Reduction; Peroxiredoxins; Peroxynitrous Acid; Protein Conformation; Selenocysteine; Signal Transduction; Sulfhydryl Compounds | 2011 |
Methylselenocysteine: a promising antiangiogenic agent for overcoming drug delivery barriers in solid malignancies for therapeutic synergy with anticancer drugs.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Cysteine; Drug Synergism; Humans; Neoplasms; Organoselenium Compounds; Selenocysteine | 2011 |
Interventions that induce modifications in the tumor microenvironment.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Adhesion; Cell Hypoxia; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Cysteine; Cytotoxins; Drug Screening Assays, Antitumor; Extracellular Matrix; Genetic Therapy; Humans; Immunotherapy; Molecular Targeted Therapy; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Neoplastic Stem Cells; Neovascularization, Pathologic; Organoselenium Compounds; Radiation Tolerance; Radiotherapy; Selenocysteine; Signal Transduction; Stromal Cells; Tumor Microenvironment | 2011 |
The role of thioredoxin in the regulation of cellular processes by S-nitrosylation.
Topics: Animals; Cell Physiological Phenomena; Cysteine; Glutathione; Nitric Oxide; Nitrosation; Oxidation-Reduction; Oxidative Stress; Proteins; S-Nitrosoglutathione; S-Nitrosothiols; Selenocysteine; Signal Transduction; Thioredoxin-Disulfide Reductase; Thioredoxins | 2012 |
Biosynthesis of selenocysteine, the 21st amino acid in the genetic code, and a novel pathway for cysteine biosynthesis.
Topics: Animals; Archaea; Cysteine; Eukaryota; Genetic Code; Genomics; Mice; Selenocysteine; Selenoproteins | 2011 |
Selenocysteine robustness versus cysteine versatility: a hypothesis on the evolution of the moonlighting behaviour of peroxiredoxins.
Topics: Biocatalysis; Biological Evolution; Cysteine; Models, Molecular; Oxidation-Reduction; Peroxiredoxins; Protein Conformation; Selenocysteine | 2014 |
From protein total synthesis to peptide transamidation and metathesis: playing with the reversibility of N,S-acyl or N,Se-acyl migration reactions.
Topics: Amides; Cysteine; Peptide Library; Peptides; Proteins; Selenocysteine | 2014 |
Recent structural advances in constrained helical peptides.
Topics: Animals; Chemistry, Pharmaceutical; Cross-Linking Reagents; Cysteine; Glucuronates; Humans; Hydrocarbons; Isocyanates; Lactams; Methionine; Nitrogen; Peptides; Permeability; Protein Conformation; Proteome; Pyrazoles; Selenocysteine; Sulfhydryl Compounds | 2019 |
The Possible Mechanism of Physiological Adaptation to the Low-Se Diet and Its Health Risk in the Traditional Endemic Areas of Keshan Diseases.
Topics: Adaptation, Physiological; Animals; Cardiomyopathies; Cysteine; Diet; Enterovirus Infections; Selenium; Selenocysteine; Selenoproteins; Serine | 2022 |
The selenophosphate synthetase family: A review.
Topics: Adenosine Triphosphate; Cysteine; Hormones; Ligases; Phosphates; Phosphotransferases; Pyridoxal Phosphate; Selenium; Selenium Compounds; Selenocysteine; Selenoproteins | 2022 |
The selenocysteine toolbox: A guide to studying the 21st amino acid.
Topics: Amino Acids; Cysteine; Hormones; Selenium; Selenocysteine; Selenoproteins; Sulfur | 2022 |
Selenium in Peptide Chemistry.
Topics: Cysteine; Peptides; Selenium; Selenocysteine; Sulfur | 2023 |
2 trial(s) available for selenocysteine and cysteine
| Article | Year |
|---|---|
Selenium supplementation improves antioxidant capacity in vitro and in vivo in patients with coronary artery disease The SElenium Therapy in Coronary Artery disease Patients (SETCAP) Study.
Topics: Aged; Antioxidants; Coronary Artery Disease; Coronary Vessels; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; Erythrocytes; Female; Glutathione Peroxidase; Humans; In Vitro Techniques; Male; Middle Aged; Organoselenium Compounds; Prospective Studies; Selenocysteine; Selenomethionine; Sodium Selenite; Vasodilation | 2008 |
Methyl selenocysteine: single-dose pharmacokinetics in men.
Topics: Adult; Cohort Studies; Cysteine; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Male; Maximum Tolerated Dose; Organoselenium Compounds; Selenocysteine; Treatment Outcome | 2011 |
298 other study(ies) available for selenocysteine and cysteine
| Article | Year |
|---|---|
Genetic evidence for an androgen-regulated epididymal secretory glutathione peroxidase whose transcript does not contain a selenocysteine codon.
Topics: Amino Acid Sequence; Androgens; Animals; Base Sequence; Binding Sites; Cloning, Molecular; Codon; Cysteine; DNA; Epididymis; Glutathione Peroxidase; Macaca fascicularis; Male; Models, Molecular; Molecular Sequence Data; Molecular Structure; Organoselenium Compounds; Protein Conformation; Rats; RNA, Messenger; Selenocysteine; Sequence Homology, Nucleic Acid | 1992 |
Substitution of cysteine for selenocysteine in type I iodothyronine deiodinase reduces the catalytic efficiency of the protein but enhances its translation.
Topics: Catalysis; Cell Line, Transformed; Cysteine; Half-Life; Iodide Peroxidase; Kidney; Mutation; Placenta; Protein Biosynthesis; Selenocysteine | 1992 |
Targeted insertion of selenocysteine into the alpha subunit of formate dehydrogenase from Methanobacterium formicicum.
Topics: Base Sequence; Codon; Cysteine; Formate Dehydrogenases; Gene Expression Regulation, Bacterial; Genes, Bacterial; Methanobacterium; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Organoselenium Compounds; Plasmids; Proteins; RNA, Messenger; Selenium; Selenocysteine; Selenoproteins | 1992 |
Overproduction of a selenocysteine-containing polypeptide in Escherichia coli: the fdhF gene product.
Topics: Bacterial Proteins; Base Sequence; Cloning, Molecular; Cysteine; DNA, Bacterial; Escherichia coli; Formate Dehydrogenases; Hydrogenase; Molecular Sequence Data; Multienzyme Complexes; Organoselenium Compounds; Plasmids; RNA, Transfer, Amino Acid-Specific; Selenium; Selenocysteine | 1992 |
Comparison of selenium and sulfur analogs in cancer prevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Betaine; Cystamine; Cysteamine; Cysteine; Diet; Female; Mammary Neoplasms, Experimental; Organoselenium Compounds; Rats; Rats, Inbred Strains; Selenocysteine | 1992 |
Selenium antagonizes the induction of human heme oxygenase by arsenite and cadmium ions.
Topics: Arsenic; Arsenites; Blotting, Northern; Cadmium; Cysteine; Dose-Response Relationship, Drug; Enzyme Induction; HeLa Cells; Heme Oxygenase (Decyclizing); Humans; Immunoblotting; Selenium; Selenocysteine; Sodium Selenite | 1991 |
Cloning of murine SeGpx cDNA and synthesis of mutated GPx proteins in Escherichia coli.
Topics: Animals; Base Sequence; Cloning, Molecular; Codon; Cysteine; DNA; Escherichia coli; Gene Library; Genetic Vectors; Glutathione Peroxidase; Liver; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Plasmids; Poly A; Promoter Regions, Genetic; Restriction Mapping; RNA, Messenger; Selenium; Selenocysteine | 1991 |
Mutagenesis of selC, the gene for the selenocysteine-inserting tRNA-species in E. coli: effects on in vivo function.
Topics: Anticodon; Base Sequence; Cloning, Molecular; Consensus Sequence; Cysteine; Escherichia coli; Formate Dehydrogenases; Genes, Bacterial; Molecular Sequence Data; Mutagenesis, Insertional; Mutation; Nucleic Acid Conformation; RNA, Bacterial; RNA, Transfer, Amino Acid-Specific; Selenium; Selenocysteine | 1990 |
Products of the reaction of selenite with intracellular sulfhydryl compounds.
Topics: Antimetabolites; Autoradiography; Buthionine Sulfoximine; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cysteine; Glutathione; HeLa Cells; Humans; Methionine Sulfoximine; Organoselenium Compounds; Selenious Acid; Selenium; Selenium Compounds; Selenium Radioisotopes; Selenocysteine; Sulfhydryl Compounds; Sulfides | 1991 |
Effect of selenium compounds and thiols on human mammary tumor cells.
Topics: Aged; Antimetabolites; Breast Neoplasms; Buthionine Sulfoximine; Cell Survival; Cysteine; Female; Glutathione; Glutathione Peroxidase; Humans; Mercaptoethanol; Methionine Sulfoximine; Organoselenium Compounds; Selenic Acid; Selenious Acid; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite; Sulfhydryl Compounds; Trypan Blue; Tumor Cells, Cultured | 1991 |
Changes in ornithine decarboxylase activity and polyamine levels in response to eight different forms of selenium.
Topics: Adenosylmethionine Decarboxylase; Animals; Cysteine; Enzyme Induction; Female; Liver; Methylation; Organoselenium Compounds; Ornithine Decarboxylase; Oxidation-Reduction; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Selenium; Selenium Compounds; Selenocysteine; Spermidine; Spermine; Structure-Activity Relationship | 1991 |
Chemical form of selenium, critical metabolites, and cancer prevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Arsenic; Arsenites; Cysteine; Female; Glutathione Peroxidase; Liver; Mammary Neoplasms, Experimental; Organoselenium Compounds; Oxides; Rats; Rats, Inbred Strains; Selenious Acid; Selenium; Selenocysteine | 1991 |
Type I iodothyronine deiodinase is a selenocysteine-containing enzyme.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Codon; Cysteine; DNA; DNA Mutational Analysis; Iodide Peroxidase; Molecular Sequence Data; Proteins; Rats; Selenium; Selenocysteine; Selenoproteins; Structure-Activity Relationship; Transfection | 1991 |
Selenoprotein A component of the glycine reductase complex from Clostridium purinolyticum: nucleotide sequence of the gene shows that selenocysteine is encoded by UGA.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; Clostridium; Codon; Cysteine; Genes, Bacterial; Molecular Sequence Data; Molecular Structure; Multienzyme Complexes; Nucleic Acid Conformation; Restriction Mapping; RNA, Messenger; Selenium; Selenocysteine; Selenoproteins | 1991 |
Inhibition of cell colony formation by selenite: involvement of glutathione.
Topics: Buthionine Sulfoximine; Cell Division; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Glutathione; HeLa Cells; Humans; In Vitro Techniques; Methionine Sulfoximine; Selenious Acid; Selenium; Selenocysteine; Sulfhydryl Compounds | 1991 |
Metalloselenonein, the selenium analogue of metallothionein: synthesis and characterization of its complex with copper ions.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Circular Dichroism; Copper; Cysteine; Metallothionein; Neurospora crassa; Selenium; Selenocysteine; Spectrometry, Fluorescence; Spectrum Analysis; Structure-Activity Relationship | 1991 |
Evidence that cysteine, not selenocysteine, is in the catalytic site of type II iodothyronine deiodinase.
Topics: Adipose Tissue, Brown; Animals; Aurothioglucose; Binding Sites; Binding, Competitive; Cysteine; Glutathione Peroxidase; Iodide Peroxidase; Liver; Male; Pituitary Gland; Rats; Rats, Inbred Strains; Selenium; Selenocysteine | 1991 |
Amino acid sequence analysis of Escherichia coli formate dehydrogenase (FDHH) confirms that TGA in the gene encodes selenocysteine in the gene product.
Topics: Amino Acid Sequence; Amino Acids; Base Sequence; beta-Galactosidase; Chromatography, Liquid; Codon; Cysteine; Endopeptidases; Escherichia coli; Formate Dehydrogenases; Genes, Bacterial; Metalloendopeptidases; Molecular Sequence Data; Peptides; Recombinant Fusion Proteins; Selenium; Selenocysteine | 1991 |
Selenoprotein A component of the glycine reductase complex from Clostridium purinolyticum: nucleotide sequence of the gene shows that selenocysteine is encoded by UGA.
Topics: Amino Acid Oxidoreductases; Bacterial Proteins; Base Sequence; Clostridium; Cysteine; Genes, Bacterial; Molecular Sequence Data; Multienzyme Complexes; Selenium; Selenocysteine; Selenoproteins | 1991 |
Selenocysteine confers the biochemical properties characteristic of the type I iodothyronine deiodinase.
Topics: Animals; Cysteine; DNA; Iodide Peroxidase; Kinetics; Male; Mutagenesis, Site-Directed; Plasmids; Rats; Rats, Inbred Strains; RNA, Messenger; Selenium; Selenocysteine; Transfection; Triiodothyronine; Xenopus | 1991 |
Recognition of UGA as a selenocysteine codon in type I deiodinase requires sequences in the 3' untranslated region.
Topics: Animals; Base Sequence; Chromosome Deletion; Chromosome Inversion; Codon; Cysteine; Humans; Iodide Peroxidase; Molecular Sequence Data; Nucleic Acid Conformation; Protein Biosynthesis; Rats; Reticulocytes; RNA, Messenger; Selenium; Selenocysteine; Sequence Homology, Nucleic Acid | 1991 |
Nitrate-inducible formate dehydrogenase in Escherichia coli K-12. I. Nucleotide sequence of the fdnGHI operon and evidence that opal (UGA) encodes selenocysteine.
Topics: Amino Acid Sequence; Base Sequence; beta-Galactosidase; Cloning, Molecular; Codon; Cysteine; Cytochrome b Group; Enzyme Induction; Escherichia coli; Formate Dehydrogenases; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Genes, Bacterial; Genotype; Molecular Sequence Data; Nitrates; Oligodeoxyribonucleotides; Open Reading Frames; Operon; Organoselenium Compounds; Plasmids; Recombinant Fusion Proteins; Restriction Mapping; Selenocysteine; Sequence Homology, Nucleic Acid | 1991 |
Nitrate-inducible formate dehydrogenase in Escherichia coli K-12. II. Evidence that a mRNA stem-loop structure is essential for decoding opal (UGA) as selenocysteine.
Topics: Base Composition; Base Sequence; Cloning, Molecular; Codon; Cysteine; Enzyme Induction; Escherichia coli; Formate Dehydrogenases; Genotype; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrates; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Organoselenium Compounds; Plasmids; RNA, Messenger; Selenocysteine | 1991 |
Selenocysteyl-tRNA occurs in the diatom Thalassiosira and in the ciliate Tetrahymena.
Topics: Animals; Codon; Cysteine; Enterobacteriaceae; Eukaryota; Fungi; Genetic Code; Organoselenium Compounds; Selenocysteine; Species Specificity; Tetrahymena | 1991 |
The function of selenocysteine synthase and SELB in the synthesis and incorporation of selenocysteine.
Topics: Bacterial Proteins; Binding Sites; Chromatography, Thin Layer; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Organoselenium Compounds; Oxidation-Reduction; Protein Biosynthesis; Pyridoxal Phosphate; RNA, Transfer, Amino Acid-Specific; RNA, Transfer, Amino Acyl; Selenocysteine; Transferases | 1991 |
Combination of blocking agents and suppressing agents in cancer prevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Allyl Compounds; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Cysteine; Drug Antagonism; Drug Synergism; Ellagic Acid; Female; Mammary Neoplasms, Experimental; Organoselenium Compounds; Quercetin; Rats; Rats, Inbred Strains; Selenium; Selenocysteine; Selenomethionine; Sulfides | 1991 |
Selenocysteine tRNA[Ser]Sec gene is ubiquitous within the animal kingdom.
Topics: Animals; Base Sequence; Biological Evolution; Blotting, Southern; Caenorhabditis; Codon; Cysteine; Drosophila melanogaster; Genes; Molecular Sequence Data; Nucleic Acid Conformation; Phylogeny; RNA, Transfer; RNA, Transfer, Amino Acid-Specific; Selenium; Selenocysteine; Suppression, Genetic; Xenopus laevis | 1990 |
Purification and biochemical characterization of SELB, a translation factor involved in selenoprotein synthesis.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; Codon; Cysteine; Escherichia coli; Gene Expression; Immunoblotting; Molecular Sequence Data; Peptide Elongation Factor Tu; Peptide Elongation Factors; Peptide Fragments; Plasmids; Protein Biosynthesis; Proteins; RNA, Messenger; Selenium; Selenocysteine; Selenoproteins; Sequence Homology, Nucleic Acid; T-Phages; Trypsin | 1990 |
Features of the formate dehydrogenase mRNA necessary for decoding of the UGA codon as selenocysteine.
Topics: Aldehyde Oxidoreductases; Base Sequence; beta-Galactosidase; Cloning, Molecular; Codon; Cysteine; DNA, Recombinant; Escherichia coli; Formate Dehydrogenases; Gene Expression; Genotype; Kinetics; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotide Probes; Restriction Mapping; RNA, Messenger; Selenium; Selenium Radioisotopes; Selenocysteine | 1990 |
Biosynthesis of selenium-modified tRNAs in Methanococcus vannielii.
Topics: Amino Acids; Carbon Radioisotopes; Cysteine; Euryarchaeota; Kinetics; RNA, Transfer; RNA, Transfer, Amino Acyl; Selenium; Selenium Radioisotopes; Selenocysteine; Selenomethionine | 1990 |
Multiple selenocysteine content of selenoprotein P in rats.
Topics: Animals; Chromatography, High Pressure Liquid; Cysteine; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Metalloendopeptidases; Peptide Fragments; Proteins; Rats; Selenium; Selenocysteine; Selenoprotein P; Selenoproteins; Serine Endopeptidases; Trypsin | 1990 |
Isolation and characterization of a selenium metabolism mutant of Salmonella typhimurium.
Topics: Chromatography, High Pressure Liquid; Chromosome Mapping; Cysteine; Formate Dehydrogenases; Genes, Bacterial; Mutation; RNA, Bacterial; RNA, Transfer; Salmonella typhimurium; Selenium; Selenocysteine | 1988 |
Occurrence and functional compatibility within Enterobacteriaceae of a tRNA species which inserts selenocysteine into protein.
Topics: Bacterial Proteins; Base Sequence; Cloning, Molecular; Cysteine; DNA Transposable Elements; DNA, Recombinant; Enterobacteriaceae; Escherichia coli; Genes, Bacterial; Molecular Sequence Data; Proteus vulgaris; RNA, Bacterial; RNA, Transfer, Amino Acid-Specific; RNA, Transfer, Ser; Selenium; Selenocysteine | 1989 |
Evidence for selenocysteine coordination to the active site nickel in the [NiFeSe]hydrogenases from Desulfovibrio baculatus.
Topics: Binding Sites; Cysteine; Desulfovibrio; Hydrogenase; Iron; Metalloendopeptidases; Nickel; Oxidation-Reduction; Protein Conformation; Selenium; Selenocysteine; Spectrum Analysis | 1989 |
Transcription of Xenopus selenocysteine tRNA Ser (formerly designated opal suppressor phosphoserine tRNA) gene is directed by multiple 5'-extragenic regulatory elements.
Topics: Amino Acid Sequence; Animals; Base Sequence; Chickens; Chromosome Deletion; Cysteine; Genes; Humans; Molecular Sequence Data; Mutation; Rabbits; Regulatory Sequences, Nucleic Acid; RNA Polymerase III; RNA, Transfer, Amino Acid-Specific; RNA, Transfer, Ser; Selenium; Selenocysteine; Transcription, Genetic; Xenopus | 1989 |
Occurrence in vivo of selenocysteyl-tRNA(SERUCA) in Escherichia coli. Effect of sel mutations.
Topics: Base Sequence; Cysteine; Escherichia coli; Genes, Bacterial; Mutation; Plasmids; RNA, Transfer, Amino Acyl; Selenious Acid; Selenium; Selenium Radioisotopes; Selenocysteine | 1989 |
Selenium and myocardial infarction.
Topics: Cysteine; Humans; Myocardial Infarction; Selenium; Selenocysteine; Selenomethionine | 1989 |
Some evidence of the enzymatic conversion of bovine suppressor phosphoseryl-tRNA to selenocysteyl-tRNA.
Topics: Amino Acids; Animals; Cattle; Chromatography, Thin Layer; Cysteine; Glutathione; NADP; RNA, Transfer; RNA, Transfer, Amino Acyl; Selenium; Selenocysteine; Transferases | 1989 |
The selenocysteine-inserting opal suppressor serine tRNA from E. coli is highly unusual in structure and modification.
Topics: Amino Acyl-tRNA Synthetases; Base Sequence; Chromatography, High Pressure Liquid; Codon; Cysteine; Escherichia coli; Genes, Bacterial; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Transfer, Amino Acid-Specific; RNA, Transfer, Ser; Selenium; Selenocysteine; Structure-Activity Relationship; Suppression, Genetic | 1989 |
Identification of a novel translation factor necessary for the incorporation of selenocysteine into protein.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cysteine; Genes, Bacterial; Kinetics; Molecular Sequence Data; Protein Binding; Protein Biosynthesis; Proteins; RNA, Transfer, Amino Acid-Specific; Selenium; Selenocysteine; Selenoproteins; Sequence Homology, Nucleic Acid | 1989 |
Anaerobic induction of Escherichia coli formate dehydrogenase (hydrogenase-linked) is enhanced by gyrase inactivation.
Topics: Aldehyde Oxidoreductases; Aminocoumarins; Anaerobiosis; Bacterial Proteins; Coumarins; Cysteine; DNA Topoisomerases, Type II; DNA, Bacterial; DNA, Superhelical; Enzyme Induction; Escherichia coli; Formate Dehydrogenases; Nalidixic Acid; Nitrates; Novobiocin; Recombinant Fusion Proteins; Selenium; Selenocysteine; Topoisomerase II Inhibitors | 1988 |
Selenocysteine metabolism in mammals.
Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Kinetics; Liver; Lyases; Selenium; Selenocysteine; Swine | 1985 |
Nucleotide sequence and expression of the selenocysteine-containing polypeptide of formate dehydrogenase (formate-hydrogen-lyase-linked) from Escherichia coli.
Topics: Aldehyde Oxidoreductases; Base Sequence; Cloning, Molecular; Codon; Cysteine; Escherichia coli; Formate Dehydrogenases; Gene Expression Regulation; Genes, Bacterial; Molecular Weight; Protein Biosynthesis; Selenium; Selenocysteine; Suppression, Genetic | 1986 |
Distribution of selenoproteins in mouse mammary epithelial cells in vitro and in vivo.
Topics: Animals; Carrier Proteins; Cell Line; Cysteine; Epithelium; Isoelectric Point; Mammary Glands, Animal; Mice; Molecular Weight; Peptide Fragments; Proteins; Selenium; Selenocysteine; Selenoproteins | 1986 |
Chemical forms of selenium in rat tissues after administration of selenite or selenomethionine.
Topics: Animals; Chemical Phenomena; Chemistry; Cysteine; Erythrocyte Membrane; Erythrocytes; Glutathione Peroxidase; Hemoglobins; Liver; Radioisotopes; Rats; Selenious Acid; Selenium; Selenocysteine; Selenomethionine; Tissue Distribution | 1986 |
Serine incorporation into the selenocysteine moiety of glutathione peroxidase.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Cysteine; Glutathione Peroxidase; Liver; Male; Radioisotopes; Rats; Selenium; Selenocysteine; Serine; Tritium | 1987 |
Effects of dietary selenite, selenocystine and selenomethionine on selenocysteine lyase and glutathione peroxidase activities and on selenium levels in rat tissues.
Topics: Animals; Cysteine; Diet; Glutathione Peroxidase; Lyases; Male; Rats; Rats, Inbred Strains; Selenious Acid; Selenium; Selenocysteine; Selenomethionine | 1987 |
Purification and immunological studies of selenoprotein A of the clostridial glycine reductase complex.
Topics: Amino Acid Oxidoreductases; Carrier Proteins; Chromatography, High Pressure Liquid; Clostridium; Cysteine; Multienzyme Complexes; Proteins; Selenium; Selenocysteine; Selenoproteins | 1987 |
Sequence of a cDNA coding for human glutathione peroxidase confirms TGA encodes active site selenocysteine.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Cysteine; DNA; Genes; Glutathione Peroxidase; Humans; Selenium; Selenocysteine | 1987 |
Selenocysteine.
Topics: Chromatography; Cysteine; Indicators and Reagents; Selenium; Selenocysteine | 1987 |
Selenocysteine.
Topics: Cysteine; Indicators and Reagents; Magnetic Resonance Spectroscopy; Selenium; Selenocysteine; Spectrophotometry, Infrared | 1987 |
Escherichia coli genes whose products are involved in selenium metabolism.
Topics: Aldehyde Oxidoreductases; Cloning, Molecular; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Formate Dehydrogenases; Genes, Bacterial; Genetic Complementation Test; Mutation; Plasmids; Promoter Regions, Genetic; Selenium; Selenocysteine | 1988 |
Selenoprotein A of the clostridial glycine reductase complex: purification and amino acid sequence of the selenocysteine-containing peptide.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Amino Acids; Bacterial Proteins; Clostridium; Cysteine; Multienzyme Complexes; Peptide Fragments; Peptide Hydrolases; Selenium; Selenocysteine; Selenoproteins | 1988 |
Genetic code: enter a new amino acid.
Topics: Base Sequence; Codon; Cysteine; Escherichia coli; Formate Dehydrogenases; Gene Expression Regulation; RNA, Messenger; Selenium; Selenocysteine | 1988 |
Gene for a novel tRNA species that accepts L-serine and cotranslationally inserts selenocysteine.
Topics: Base Sequence; Cloning, Molecular; Cysteine; Escherichia coli; Genes, Bacterial; Molecular Sequence Data; Nucleic Acid Conformation; Plasmids; Protein Biosynthesis; RNA, Transfer; Selenium; Selenocysteine; Serine | 1988 |
The conversion of phosphoserine residues to selenocysteine residues on an opal suppressor tRNA and casein.
Topics: Animals; Base Sequence; Caseins; Cattle; Codon; Cysteine; Glutathione Peroxidase; Liver; Phosphoserine; Protein Processing, Post-Translational; RNA, Messenger; RNA, Transfer; Selenium; Selenocysteine; Serine | 1988 |
A termination codon specifies selenocysteine in glutathione peroxidase.
Topics: Animals; Codon; Cysteine; Glutathione Peroxidase; Mice; RNA, Messenger; Selenium; Selenocysteine | 1988 |
Oxidative deamination of Se-(1-carboxyethyl)-,Se-(1-carboxypropyl)- and Se-(2-carboxyethyl)-selenocysteine by snake venom L-aminoacid oxidase.
Topics: Amino Acid Oxidoreductases; Cysteine; Indicators and Reagents; Kinetics; L-Amino Acid Oxidase; Oxygen Consumption; Selenium; Selenocysteine; Snake Venoms; Structure-Activity Relationship; Substrate Specificity | 1988 |
Selenocysteine on glutathione peroxidase may be converted from phosphoserine on the apo-enzyme synthesized with an opal suppressor phosphoseryl-tRNA.
Topics: Animals; Apoenzymes; Apoproteins; Binding Sites; Cattle; Cysteine; Genes; Glutathione Peroxidase; Liver; Phosphoserine; Protein Biosynthesis; Protein Processing, Post-Translational; RNA, Transfer, Amino Acyl; Selenium; Selenocysteine; Serine; Suppression, Genetic | 1988 |
Selenocysteine's mechanism of incorporation and evolution revealed in cDNAs of three glutathione peroxidases.
Topics: Animals; Base Sequence; Cattle; Cysteine; DNA; Glutathione Peroxidase; Humans; Mice; Molecular Sequence Data; Molecular Structure; Selenium; Selenocysteine | 1988 |
[Scavenging of active oxygen by selenium].
Topics: Animals; Cysteine; Humans; Lipid Peroxidation; Selenium; Selenocysteine; Selenomethionine | 1988 |
Selenocysteine, a highly specific component of certain enzymes, is incorporated by a UGA-directed co-translational mechanism.
Topics: Amino Acid Oxidoreductases; Animals; Clostridium; Codon; Cysteine; Escherichia coli; Glutathione Peroxidase; Multienzyme Complexes; Mutation; Oxidoreductases; Protein Biosynthesis; RNA, Transfer; Selenium; Selenocysteine; Terminator Regions, Genetic | 1988 |
The structure of the mouse glutathione peroxidase gene: the selenocysteine in the active site is encoded by the 'termination' codon, TGA.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Line; Codon; Cysteine; DNA Restriction Enzymes; Genes; Glutathione Peroxidase; Leukemia, Experimental; Mice; Mice, Inbred BALB C; Reticulocytes; RNA, Messenger; Selenium; Selenocysteine; Transcription, Genetic | 1986 |
Cotranslational insertion of selenocysteine into formate dehydrogenase from Escherichia coli directed by a UGA codon.
Topics: Aldehyde Oxidoreductases; Amino Acid Sequence; Base Sequence; Codon; Cysteine; DNA Restriction Enzymes; Escherichia coli; Formate Dehydrogenases; Genes; Genes, Bacterial; Mutation; Nucleic Acid Hybridization; Plasmids; Protein Biosynthesis; RNA, Messenger; Selenious Acid; Selenium; Selenocysteine | 1987 |
Abundance and tissue distribution of selenocysteine-containing proteins in the rat.
Topics: Animals; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Glutathione Peroxidase; Male; Proteins; Rats; Rats, Inbred Strains; Selenium; Selenocysteine; Tissue Distribution | 1985 |
Mechanism of reactions catalyzed by selenocysteine beta-lyase.
Topics: Alanine; Animals; Binding Sites; Cysteine; In Vitro Techniques; Keto Acids; Liver; Lyases; Pyridoxamine; Selenium; Selenocysteine; Swine | 1985 |
The incorporation of radioactivity from a mixture of selenium-75 and (methyl- 3 H)selenomethionines into selenomethylselenocysteine.
Topics: Biological Transport; Cysteine; Methionine; Methylation; Plants; Radioisotopes; Selenium; Selenocysteine; Tritium | 1973 |
A selenium-containing hydrogenase from Methanococcus vannielii. Identification of the selenium moiety as a selenocysteine residue.
Topics: Cysteine; Euryarchaeota; Hydrogenase; Macromolecular Substances; Molecular Weight; Oxidoreductases; Selenium; Selenocysteine | 1982 |
Selenocysteine-containing proteins from rat and monkey plasma.
Topics: Animals; Blood Proteins; Carrier Proteins; Cysteine; Male; Rats; Selenium; Selenocysteine; Time Factors | 1982 |
A selenocysteine-containing selenium-transport protein in rat plasma.
Topics: Animals; Biological Transport, Active; Carrier Proteins; Cysteine; Glutathione Peroxidase; Kidney; Liver; Male; Proteins; Rats; Rats, Inbred Strains; Selenium; Selenocysteine; Selenoprotein P; Selenoproteins; Time Factors; Tissue Distribution | 1982 |
Selenium and selenoproteins in the rat kidney.
Topics: Animals; Carrier Proteins; Cysteine; Kidney; Liver; Lysosomes; Macromolecular Substances; Male; Molecular Weight; Organ Specificity; Proteins; Rats; Rats, Inbred Strains; Selenium; Selenocysteine; Selenoproteins | 1982 |
Amino acid sequence around the active-site selenocysteine of rat liver glutathione peroxidase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cysteine; Glutathione Peroxidase; Liver; Peptide Fragments; Peroxidases; Rats; Selenium; Selenocysteine | 1982 |
In vitro synthesis of glutathione peroxidase from selenite. Translational incorporation of selenocysteine.
Topics: Animals; Cell-Free System; Cysteine; Glutathione Peroxidase; In Vitro Techniques; Liver; Male; Peroxidases; Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA, Transfer; Selenious Acid; Selenium; Selenocysteine | 1983 |
Microbial distribution of selenocysteine lyase.
Topics: Alcaligenes; Bacteria; Cysteine; Cytoplasm; Fungi; Kinetics; Lyases; Pseudomonas; Pyridoxal Phosphate; Selenium; Selenocysteine; Yeasts | 1983 |
Purification and characterization of selenium-glutathione peroxidase from hamster liver.
Topics: Amino Acids; Animals; Cricetinae; Cysteine; Glutathione Peroxidase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Selenium; Selenocysteine; Substrate Specificity | 1983 |
Identification of selenocysteine in glutathione peroxidase by mass spectroscopy.
Topics: 2,4-Dinitrophenol; Animals; Chemical Phenomena; Chemistry; Cysteine; Dinitrophenols; Erythrocytes; Glutathione Peroxidase; Mass Spectrometry; Selenium; Selenocysteine; Sheep | 1983 |
Selenocysteine beta-lyase: a novel pyridoxal enzyme.
Topics: Animals; Bacteria; Cysteine; Hydrogen-Ion Concentration; Liver; Lyases; Pyridoxal Phosphate; Selenium; Selenocysteine; Substrate Specificity; Swine; Tissue Distribution | 1984 |
Reaction and regulation mechanisms of selenocysteine beta-lyase.
Topics: Aluminum; Animals; Cysteine; Dithiothreitol; Keto Acids; Liver; Lyases; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Pyridoxamine; Selenium; Selenocysteine; Swine | 1984 |
The nutritional biochemistry of selenium.
Topics: Animal Feed; Animals; Antioxidants; Chemical Phenomena; Chemistry, Physical; Cysteine; Erythrocytes; Food Analysis; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Intestinal Absorption; Methylation; Nutritional Physiological Phenomena; Oxidation-Reduction; Rumen; Selenious Acid; Selenium; Selenocysteine; Selenomethionine; Species Specificity; Tissue Distribution; Vitamin E | 1984 |
Selenium--glutathione peroxidase: properties and synthesis.
Topics: Amino Acid Sequence; Animals; Aurothioglucose; Cysteine; Glutathione Peroxidase; Gold; Humans; Kinetics; Liver; Penicillamine; Protein Biosynthesis; RNA, Transfer, Amino Acyl; Selenious Acid; Selenium; Selenocysteine | 1984 |
Occurrence and characterization of selenocysteine in proteins.
Topics: Amino Acid Oxidoreductases; Animals; Bacteria; Chromatography, Thin Layer; Cysteine; Formate Dehydrogenases; Glutathione Peroxidase; Humans; Isotope Labeling; Macromolecular Substances; Molecular Weight; Multienzyme Complexes; Proteins; Selenium; Selenocysteine | 1984 |
Identification of selenocysteine by high-performance liquid chromatography and mass spectrometry.
Topics: Amino Acids; Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cysteine; Dinitrophenols; Electrophoresis; Gas Chromatography-Mass Spectrometry; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Proteins; Selenium; Selenocysteine; Spectrophotometry | 1984 |
Selenocysteine-containing proteins and glutathione peroxidase.
Topics: Animals; Binding Sites; Carrier Proteins; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cysteine; Glutathione Peroxidase; Kidney; Liver; Macromolecular Substances; Male; Molecular Weight; Protein Biosynthesis; Proteins; Radioisotope Dilution Technique; Radioisotopes; Rats; Rats, Inbred Strains; Selenium; Selenocysteine; Selenoproteins | 1984 |
Reduction of DL-selenocystine and isolation of L-seleoncysteine.
Topics: Amino Acyl-tRNA Synthetases; Borohydrides; Chemistry, Organic; Cysteine; Cystine; Dithiothreitol; Mercaptoethanol; Methods; Organic Chemistry Phenomena; Organoselenium Compounds; Oxidation-Reduction; Paracoccus denitrificans; Plants; Selenium; Selenocysteine; Substrate Specificity | 1980 |
The Raman spectra of selenomethionine and selenocystine.
Topics: Cysteine; Glutathione Peroxidase; Selenium; Selenocysteine; Selenomethionine; Spectrum Analysis, Raman | 1981 |
Enzymatic synthesis of selenocysteine in rat liver.
Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Hydro-Lyases; Kinetics; Liver; Lyases; Mass Spectrometry; Rats; Selenium; Selenocysteine | 1981 |
Evidence for selenocysteine in ovine tissue organelles.
Topics: Animals; Cell Nucleus; Cysteine; Liver; Microsomes; Microsomes, Liver; Mitochondria, Heart; Mitochondria, Liver; Myocardium; Proteins; Selenium; Selenocysteine; Sheep; Subcellular Fractions | 1981 |
Selenocysteine lyase, a novel enzyme that specifically acts on selenocysteine. Mammalian distribution and purification and properties of pig liver enzyme.
Topics: Animals; Cysteine; Liver; Lyases; Molecular Weight; Selenium; Selenocysteine; Species Specificity; Spectrophotometry; Substrate Specificity; Swine; Tissue Distribution | 1982 |
Synthesis of [75Se]trimethylselenonium iodide from [75Se]selenocystine.
Topics: Borohydrides; Chemical Phenomena; Chemistry; Cysteine; Cystine; Hydrocarbons, Iodinated; Methods; Organometallic Compounds; Organoselenium Compounds; Radioisotopes; Selenium; Selenium Compounds; Selenocysteine | 1984 |
Dissociation of the genotoxic and growth inhibitory effects of selenium.
Topics: Animals; Cell Death; Cell Division; Cysteine; DNA, Single-Stranded; Dose-Response Relationship, Drug; Mice; Organoselenium Compounds; Selenium; Selenium Compounds; Selenocysteine; Sodium Selenite; Tumor Cells, Cultured | 1995 |
Coordination of selenium to molybdenum in formate dehydrogenase H from Escherichia coli.
Topics: Amino Acid Sequence; Conserved Sequence; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Formate Dehydrogenases; Hydrogenase; Isotope Labeling; Ligands; Metalloproteins; Molecular Sequence Data; Molybdenum; Multienzyme Complexes; Selenium; Selenocysteine; Sequence Homology, Amino Acid; Serine | 1994 |
The formation of diselenide bridges in proteins by incorporation of selenocysteine residues: biosynthesis and characterization of (Se)2-thioredoxin.
Topics: Chromatography, High Pressure Liquid; Cysteine; DNA-Directed RNA Polymerases; Escherichia coli; Isoelectric Focusing; Mass Spectrometry; Oxidation-Reduction; Recombinant Proteins; RNA, Transfer, Cys; Selenium; Selenocysteine; Structure-Activity Relationship; Thioredoxins; Viral Proteins | 1994 |
Effect on an aqueous extract of selenium-enriched garlic on in vitro markers and in vivo efficacy in cancer prevention.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Cycle; Cell Division; Cysteine; DNA Damage; DNA, Neoplasm; Female; Freeze Drying; Garlic; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Organoselenium Compounds; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Selenium; Selenocysteine; Sodium Selenite | 1996 |
A selenium-dependent and a selenium-independent formylmethanofuran dehydrogenase and their transcriptional regulation in the hyperthermophilic Methanopyrus kandleri.
Topics: Aldehyde Oxidoreductases; Amino Acid Sequence; Base Sequence; Blotting, Northern; Cell Extracts; Chromosome Mapping; Cloning, Molecular; Cysteine; DNA Primers; DNA, Bacterial; Euryarchaeota; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Isoenzymes; Molecular Sequence Data; Molybdenum; Selenium; Selenocysteine; Sequence Alignment; Sodium Selenite; Transcription, Genetic; Tungsten; Tungsten Compounds | 1997 |
Inhibition of cdk2 kinase activity by methylselenocysteine in synchronized mouse mammary epithelial tumor cells.
Topics: Animals; CDC2-CDC28 Kinases; Cell Cycle; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cyclins; Cysteine; DNA; Epithelium; Mammary Glands, Animal; Mice; Organoselenium Compounds; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Selenocysteine; Tumor Cells, Cultured | 1997 |
The path of unspecific incorporation of selenium in Escherichia coli.
Topics: Acetyltransferases; Bacterial Proteins; Cysteine; Cysteine Synthase; Escherichia coli; Feedback; Models, Chemical; Mutation; Proteins; Selenium; Selenocysteine; Selenoproteins; Serine O-Acetyltransferase; Sulfates; Sulfites; Trans-Activators | 1997 |
Characterization of a mammalian peroxiredoxin that contains one conserved cysteine.
Topics: Amino Acid Sequence; Conserved Sequence; Cysteine; Disulfides; Dithionitrobenzoic Acid; Dithiothreitol; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Models, Chemical; Molecular Sequence Data; Neoplasm Proteins; Oxidation-Reduction; Peroxidases; Peroxiredoxin III; Peroxiredoxins; Phospholipases A; Phospholipases A2; Proteins; Recombinant Proteins; Selenocysteine; Sequence Homology, Amino Acid; Subcellular Fractions | 1998 |
Mammalian thioredoxin reductase is irreversibly inhibited by dinitrohalobenzenes by alkylation of both the redox active selenocysteine and its neighboring cysteine residue.
Topics: Alkylation; Amino Acid Sequence; Animals; Cattle; Chromatography, High Pressure Liquid; Cysteine; Dinitrochlorobenzene; Enzyme Inhibitors; Mass Spectrometry; Molecular Sequence Data; Oxidation-Reduction; Pyridines; Selenocysteine; Superoxides; Thioredoxin-Disulfide Reductase | 1998 |
Distribution of free seleno-amino acids in plant tissue of Melilotus indica L. grown in selenium-laden soils.
Topics: Amino Acids; Antiviral Agents; Cysteine; Cystine; Fabaceae; Gas Chromatography-Mass Spectrometry; Organoselenium Compounds; Plants, Edible; Plants, Medicinal; Selenium; Selenocysteine; Selenomethionine; Soil; Sulfhydryl Reagents | 1998 |
Evidence that peroxiredoxins are novel members of the thioredoxin fold superfamily.
Topics: Amino Acid Sequence; Antioxidants; Binding Sites; Catalysis; Cysteine; Glutathione Peroxidase; Molecular Sequence Data; Oxidation-Reduction; Peroxidases; Peroxiredoxins; Protein Folding; Selenocysteine; Sequence Alignment; Thioredoxins | 1998 |
Substituting selenocysteine for active site cysteine 149 of phosphorylating glyceraldehyde 3-phosphate dehydrogenase reveals a peroxidase activity.
Topics: Binding Sites; Cysteine; Geobacillus stearothermophilus; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Peroxidase; Phosphorylation; Selenocysteine | 1998 |
Catalytic properties of selenophosphate synthetases: comparison of the selenocysteine-containing enzyme from Haemophilus influenzae with the corresponding cysteine-containing enzyme from Escherichia coli.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Bacterial Proteins; Catalysis; Cloning, Molecular; Cysteine; Drosophila Proteins; Escherichia coli; Haemophilus influenzae; Molecular Sequence Data; Phosphotransferases; Recombinant Proteins; Selenium Compounds; Selenocysteine; Sequence Analysis; Sequence Homology, Amino Acid; Species Specificity | 1999 |
Acquisition of selenium tolerance by a selenium non-accumulating Astragalus species via selection.
Topics: Blotting, Western; Cell Division; Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; Drug Tolerance; Electrophoresis, Gel, Two-Dimensional; Enzyme Induction; Isoelectric Point; Methylation; Methyltransferases; Organoselenium Compounds; Plant Cells; Plant Proteins; Plants; Selection, Genetic; Selenium; Selenocysteine; Sodium Selenite; Time Factors | 1999 |
Electric fields in active sites: substrate switching from null to strong fields in thiol- and selenol-subtilisins.
Topics: Acylation; Alanine; Amino Acid Substitution; Asparagine; Binding Sites; Crystallography, X-Ray; Cysteine; Esters; Glycine; Kinetics; Models, Molecular; Proline; Protein Conformation; Selenocysteine; Spectrum Analysis, Raman; Static Electricity; Substrate Specificity; Subtilisins | 1999 |
Schizosaccharomyces pombe homologue of glutathione peroxidase, which does not contain selenocysteine, is induced by several stresses and works as an antioxidant.
Topics: Amino Acid Sequence; Antioxidants; Base Sequence; Blotting, Northern; Blotting, Southern; Cloning, Molecular; Cysteine; DNA Primers; DNA, Fungal; Electrophoresis, Agar Gel; Enzyme Induction; Gene Expression Regulation, Fungal; Glutathione Peroxidase; Hydrogen Peroxide; Molecular Sequence Data; Oxidative Stress; Pancreatitis-Associated Proteins; Polymerase Chain Reaction; RNA, Fungal; Schizosaccharomyces; Selenocysteine; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Transcription Factors | 1999 |
Effects of methylselenocysteine on PKC activity, cdk2 phosphorylation and gadd gene expression in synchronized mouse mammary epithelial tumor cells.
Topics: Animals; Anticarcinogenic Agents; Antigens, Differentiation; Blotting, Western; CCAAT-Enhancer-Binding Proteins; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Cysteine; DNA-Binding Proteins; Female; GADD45 Proteins; Gene Expression; Intracellular Signaling Peptides and Proteins; Isoenzymes; Mammary Neoplasms, Experimental; Mice; Organoselenium Compounds; Phosphorylation; Protein Kinase C; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Proteins; Selenocysteine; Thymidine; Transcription Factor CHOP; Transcription Factors; Tumor Cells, Cultured | 1999 |
Selenium modulation of cell proliferation and cell cycle biomarkers in normal and premalignant cells of the rat mammary gland.
Topics: Animals; Anticarcinogenic Agents; Antimetabolites; Antineoplastic Agents; Biomarkers; Bromodeoxyuridine; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Chemoprevention; Coloring Agents; Cyclin D; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Cysteine; Enzyme Inhibitors; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Microtubule-Associated Proteins; Organoselenium Compounds; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Selenocysteine; Tumor Suppressor Proteins | 2000 |
Mammalian thioredoxin reductase: oxidation of the C-terminal cysteine/selenocysteine active site forms a thioselenide, and replacement of selenium with sulfur markedly reduces catalytic activity.
Topics: Animals; Binding Sites; Chromatography, High Pressure Liquid; Cysteine; Dose-Response Relationship, Drug; Escherichia coli; Humans; Liver; Models, Chemical; Mutagenesis; Oxidation-Reduction; Placenta; Protein Binding; Rats; Selenium; Selenocysteine; Spectrophotometry; Sulfur; Thioredoxin-Disulfide Reductase; Time Factors | 2000 |
Structure and mechanism of mammalian thioredoxin reductase: the active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine sequence.
Topics: Animals; Binding Sites; Cattle; Cysteine; Glutathione Reductase; Mass Spectrometry; Models, Molecular; NADP; Oxidation-Reduction; Selenocysteine; Thioredoxin-Disulfide Reductase | 2000 |
Eukaryotic selenocysteine incorporation follows a nonprocessive mechanism that competes with translational termination.
Topics: 3' Untranslated Regions; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Codon; Cysteine; Humans; Mice; Molecular Sequence Data; Mutagenesis, Insertional; Oligodeoxyribonucleotides; Peptide Chain Termination, Translational; Plasmids; Protein Biosynthesis; Proteins; RNA, Transfer, Amino Acid-Specific; Selenocysteine; Selenoproteins; Sequence Alignment; Sequence Homology, Amino Acid; Xenopus | 2000 |
Substituting selenocysteine for catalytic cysteine 41 enhances enzymatic activity of plant phospholipid hydroperoxide glutathione peroxidase expressed in Escherichia coli.
Topics: Amino Acid Sequence; Base Sequence; Catalytic Domain; Citrus; Cysteine; Escherichia coli; Glutathione Peroxidase; Molecular Sequence Data; Phospholipid Hydroperoxide Glutathione Peroxidase; Protein Engineering; Recombinant Proteins; RNA, Transfer, Amino Acid-Specific; Selenocysteine; Structure-Activity Relationship | 2000 |
Purification, crystallization and preliminary crystallographic data for rat cytosolic selenocysteine 498 to cysteine mutant thioredoxin reductase.
Topics: Crystallization; Crystallography, X-Ray; Cysteine; Escherichia coli; Mutation; Selenocysteine; Thioredoxin-Disulfide Reductase | 2000 |
L-Selenohomocysteine: one-step synthesis from L-selenomethionine and kinetic analysis as substrate for methionine synthases.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Anticarcinogenic Agents; Chromatography, High Pressure Liquid; Cysteine; Female; Humans; Kinetics; Male; Molecular Structure; Organoselenium Compounds; Oxidation-Reduction; Selenium; Selenocysteine; Selenomethionine | 2000 |
Tumorigenesis, metabolism, speciation, bioavailability, and tissue deposition of selenium in selenium-enriched ramps (Allium tricoccum).
Topics: Allium; Animals; Anticarcinogenic Agents; Biological Availability; Cystathionine; Cysteine; Diet; Dipeptides; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Selenium; Selenocysteine; Tissue Distribution | 2000 |
The putative glutathione peroxidase gene of Plasmodium falciparum codes for a thioredoxin peroxidase.
Topics: Amino Acid Sequence; Animals; Cattle; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Escherichia coli; Glutathione; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Kinetics; Models, Chemical; Molecular Sequence Data; Neoplasm Proteins; Peroxidases; Peroxiredoxin III; Peroxiredoxins; Phosphatidylcholines; Plasmodium falciparum; Selenocysteine; Sequence Homology, Amino Acid | 2001 |
The role of selenocysteine 133 in catalysis by the human type 2 iodothyronine deiodinase.
Topics: Alanine; Catalysis; Cell Line; Cysteine; Gene Expression; Humans; Iodide Peroxidase; Iodine Radioisotopes; Kinetics; Mutagenesis; Recombinant Proteins; Selenocysteine; Structure-Activity Relationship; Thyroxine; Transfection; Triiodothyronine | 2000 |
Characterization of the zinc sites in cobalamin-independent and cobalamin-dependent methionine synthase using zinc and selenium X-ray absorption spectroscopy.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bacterial Proteins; Binding Sites; Cysteine; Escherichia coli; Escherichia coli Proteins; Methyltransferases; Organoselenium Compounds; Selenium; Selenocysteine; Spectrum Analysis; Substrate Specificity; Vitamin B 12; X-Rays; Zinc | 2001 |
Selenoxidation by flavin-containing monooxygenases as a novel pathway for beta-elimination of selenocysteine Se-conjugates.
Topics: Animals; Cysteine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Male; Microsomes, Liver; Oxidation-Reduction; Oxygenases; Pyruvic Acid; Rats; Rats, Wistar; Recombinant Proteins; Selenium Compounds; Selenium Oxides; Selenocysteine | 2001 |
Se-methylselenocysteine induces apoptosis through caspase activation in HL-60 cells.
Topics: Amino Acid Chloromethyl Ketones; Anticarcinogenic Agents; Apoptosis; Caspase 3; Caspases; Cysteine; DNA Damage; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; HL-60 Cells; Humans; Immunoblotting; In Situ Nick-End Labeling; Organoselenium Compounds; Poly(ADP-ribose) Polymerases; Selenocysteine; Sodium Selenite; Time Factors | 2001 |
Characterization of the biological activity of gamma-glutamyl-Se-methylselenocysteine: a novel, naturally occurring anticancer agent from garlic.
Topics: Animals; Anticarcinogenic Agents; Cysteine; Female; Gene Expression Regulation, Neoplastic; Intestinal Absorption; Mammary Neoplasms, Experimental; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Selenium; Selenocysteine | 2001 |
Roles of N-terminal active cysteines and C-terminal cysteine-selenocysteine in the catalytic mechanism of mammalian thioredoxin reductase.
Topics: Animals; Baculoviridae; Catalysis; COS Cells; Cysteine; Electron Transport; Flavin-Adenine Dinucleotide; Insecta; Mammals; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Structure, Tertiary; Rats; Selenocysteine; Thioredoxin-Disulfide Reductase; Thioredoxins | 2001 |
Se-methylselenocysteine induces apoptosis mediated by reactive oxygen species in HL-60 cells.
Topics: Acetylcysteine; Anticarcinogenic Agents; Antioxidants; Apoptosis; Blotting, Western; Caspases; Cell Survival; Cysteine; Cytochrome c Group; Enzyme Activation; Flow Cytometry; HeLa Cells; HL-60 Cells; Humans; Membrane Potentials; Organoselenium Compounds; Reactive Oxygen Species; Selenocysteine | 2001 |
Se-methylselenocysteine activates caspase-3 in mouse mammary epithelial tumor cells in vitro.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Caspase 3; Caspases; Cell Cycle; Cysteine; DNA Fragmentation; DNA, Neoplasm; Enzyme Activation; Female; Mammary Neoplasms, Experimental; Mice; Organoselenium Compounds; Selenocysteine; Thymidine; Tumor Cells, Cultured | 2001 |
Modeling the active sites in metalloenzymes 5. The heterolytic bond cleavage of H(2) in the [NiFe] hydrogenase of desulfovibrio gigas by a nucleophilic addition mechanism.
Topics: Binding Sites; Catalysis; Catalytic Domain; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Cysteine; Desulfovibrio; Hydrogen; Hydrogenase; Iron; Metalloproteins; Models, Molecular; Molecular Conformation; Molecular Structure; Nickel; Oxidation-Reduction; Selenocysteine; Spectrophotometry, Infrared | 2001 |
Dimethyldiselenide and methylseleninic acid generate superoxide in an in vitro chemiluminescence assay in the presence of glutathione: implications for the anticarcinogenic activity of L-selenomethionine and L-Se-methylselenocysteine.
Topics: Anticarcinogenic Agents; Cysteine; Glutathione; Glutathione Peroxidase; Kinetics; Luminescent Measurements; Organoselenium Compounds; Selenocysteine; Selenomethionine; Superoxide Dismutase; Superoxides | 2001 |
Analysis of the E. coli NifS CsdB protein at 2.0 A reveals the structural basis for perselenide and persulfide intermediate formation.
Topics: Apoenzymes; Bacillus subtilis; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cysteine; Disulfides; Escherichia coli; Ligands; Lyases; Models, Molecular; Organoselenium Compounds; Protein Conformation; Selenocysteine; Structure-Activity Relationship; Sulfides; Thermodynamics | 2002 |
Substitution of cysteine for a conserved alanine residue in the catalytic center of type II iodothyronine deiodinase alters interaction with reducing cofactor.
Topics: Alanine; Amino Acid Substitution; Animals; Catalysis; COS Cells; Cysteine; Dithiothreitol; Genetic Vectors; Humans; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Kinetics; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Selenocysteine; Thyroxine; Triiodothyronine | 2002 |
Mammalian selenoprotein gene signature: identification and functional analysis of selenoprotein genes using bioinformatics methods.
Topics: 3' Untranslated Regions; Amino Acid Sequence; Animals; Base Sequence; Codon; Computational Biology; Cysteine; Databases, Genetic; DNA Transposable Elements; Drosophila melanogaster; Drosophila Proteins; Genes, Insect; Humans; Multigene Family; Nucleic Acid Conformation; Proteins; RNA, Messenger; Selenocysteine; Selenoproteins | 2002 |
Structure of external aldimine of Escherichia coli CsdB, an IscS/NifS homolog: implications for its specificity toward selenocysteine.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Carbon-Sulfur Lyases; Crystallography, X-Ray; Cysteine; Escherichia coli; Lyases; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Pyridoxal Phosphate; Selenocysteine; Sequence Homology, Amino Acid; Substrate Specificity | 2002 |
Se-methylselenocysteine induces apoptosis through caspase activation and Bax cleavage mediated by calpain in SKOV-3 ovarian cancer cells.
Topics: Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Calpain; Caspases; Cysteine; Cytochrome c Group; Enzyme Activation; Female; Humans; Inhibitor of Apoptosis Proteins; Organoselenium Compounds; Ovarian Neoplasms; Poly(ADP-ribose) Polymerases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Selenocysteine; Tumor Cells, Cultured | 2002 |
Tissue distribution of cytosolic beta-elimination reactions of selenocysteine Se-conjugates in rat and human.
Topics: Animals; Chromatography, Ion Exchange; Cysteine; Cytosol; Humans; Hydrolases; Kidney; Kinetics; Liver; Lyases; Male; Middle Aged; Organ Specificity; Organoselenium Compounds; Rats; Rats, Wistar; Selenocysteine | 2002 |
Comparative study on the bioactivation mechanisms and cytotoxicity of Te-phenyl-L-tellurocysteine, Se-phenyl-L-selenocysteine, and S-phenyl-L-cysteine.
Topics: Animals; Biotransformation; Cysteine; Cytochrome P-450 CYP1A1; D-Amino-Acid Oxidase; Enzyme Activation; Enzyme Inhibitors; Glutathione Transferase; Hepatocytes; Humans; Kidney; Kinetics; Lyases; Male; Microsomes, Liver; Organometallic Compounds; Rats; Rats, Wistar; Selenocysteine; Tellurium | 2002 |
Coupled tRNA(Sec)-dependent assembly of the selenocysteine decoding apparatus.
Topics: Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Codon; Cysteine; DNA Mutational Analysis; Gene Deletion; Glutathione Transferase; Humans; Methionine; Mice; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Plasmids; Point Mutation; Precipitin Tests; Protein Binding; Protein Biosynthesis; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Ribosomes; RNA, Transfer, Amino Acid-Specific; Selenocysteine; Sequence Homology, Amino Acid; Transfection | 2003 |
Substitution of cysteine for selenocysteine in the catalytic center of type III iodothyronine deiodinase reduces catalytic efficiency and alters substrate preference.
Topics: Alanine; Amino Acid Substitution; Animals; Catalytic Domain; COS Cells; Cysteine; Enzyme Activation; Humans; In Vitro Techniques; Iodide Peroxidase; Mutagenesis, Site-Directed; Selenocysteine; Substrate Specificity; Thyroxine; Triiodothyronine | 2003 |
Incorporation of selenomethionine into proteins through selenohomocysteine-mediated ligation.
Topics: Cysteine; Methylation; Nuclear Magnetic Resonance, Biomolecular; Organoselenium Compounds; Peptides; Protein Conformation; Protein Denaturation; Proteins; Selenocysteine; Selenomethionine | 2003 |
Biogenesis of Fe-S cluster by the bacterial Suf system: SufS and SufE form a new type of cysteine desulfurase.
Topics: Alanine; Bacterial Proteins; Carbon-Sulfur Lyases; Chromatography; Chromatography, Gel; Cysteine; Cytosol; Dickeya chrysanthemi; Dimerization; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Immunoblotting; Iron-Sulfur Proteins; Kinetics; Lyases; Models, Biological; Models, Chemical; Mutagenesis, Site-Directed; Plasmids; Protein Binding; Selenocysteine; Subcellular Fractions; Time Factors; Two-Hybrid System Techniques | 2003 |
Seleno-amino acid found in Astragalus bisulcatus.
Topics: Amino Acids; Cysteine; Plants; Selenium; Selenocysteine | 1960 |
Biosynthesis of Se-methyl-selenocysteine from selenite in selenium-accumulating plants.
Topics: Cysteine; Plants; Selenious Acid; Selenium; Selenium Compounds; Selenocysteine | 1963 |
Induction of apoptosis by Se-MSC in U937 human leukemia cells through release of cytochrome c and activation of caspases and PKC-delta: mutual regulation between caspases and PKC-delta via a positive feedback mechanism.
Topics: Acetophenones; Apoptosis; Benzopyrans; Caspases; Cysteine; Cytochromes c; Enzyme Activation; Feedback, Physiological; Humans; Organoselenium Compounds; Poly(ADP-ribose) Polymerases; Protein Kinase C; Protein Kinase C-delta; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Selenocysteine; U937 Cells | 2003 |
Selenomethionine and selenocysteine double labeling strategy for crystallographic phasing.
Topics: Animals; Antimicrobial Cationic Peptides; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Disulfides; Electrons; Escherichia coli; Mass Spectrometry; Models, Molecular; Nucleoside-Diphosphate Kinase; Oxygen; Plasmids; Protein Conformation; Proteins; Recombinant Proteins; Selenium; Selenocysteine; Selenomethionine; Spectrometry, Mass, Electrospray Ionization; Sulfur; Swine | 2003 |
Overexpression of selenocysteine methyltransferase in Arabidopsis and Indian mustard increases selenium tolerance and accumulation.
Topics: Adaptation, Physiological; Arabidopsis; Cysteine; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Methyltransferases; Molecular Sequence Data; Mustard Plant; Organoselenium Compounds; Plants, Genetically Modified; Selenium; Selenocysteine; Volatilization | 2004 |
Methionine sulfoxide reduction in mammals: characterization of methionine-R-sulfoxide reductases.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Cell Nucleus; Cysteine; Cytosol; Humans; Methionine; Methionine Sulfoxide Reductases; Microfilament Proteins; Mitochondria; Molecular Sequence Data; Oxidation-Reduction; Oxidoreductases; Protein Isoforms; Recombinant Proteins; Selenocysteine; Sequence Alignment; Transcription Factors | 2004 |
Production of Se-methylselenocysteine in transgenic plants expressing selenocysteine methyltransferase.
Topics: Arabidopsis; Astragalus Plant; Chromatography, High Pressure Liquid; Cysteine; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Mass Spectrometry; Methyltransferases; Organoselenium Compounds; Plant Shoots; Plants, Genetically Modified; Selenium; Selenocysteine; Sodium Selenite | 2004 |
Selenium derivatization and crystallization of DNA and RNA oligonucleotides for X-ray crystallography using multiple anomalous dispersion.
Topics: Base Sequence; Crystallization; Crystallography, X-Ray; Cysteine; DNA; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Oligoribonucleotides; Organophosphorus Compounds; Organoselenium Compounds; RNA; Selenium; Selenocysteine; Uridine | 2004 |
Methioninase and selenomethionine but not Se-methylselenocysteine generate methylselenol and superoxide in an in vitro chemiluminescent assay: implications for the nutritional carcinostatic activity of selenoamino acids.
Topics: Apoptosis; Carbon-Sulfur Lyases; Cells, Cultured; Cysteine; Humans; Luminescent Measurements; Organoselenium Compounds; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; Superoxides | 2004 |
Selective modulation of the therapeutic efficacy of anticancer drugs by selenium containing compounds against human tumor xenografts.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Squamous Cell; Cell Line, Tumor; Colonic Neoplasms; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Irinotecan; Maximum Tolerated Dose; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Organoselenium Compounds; Radiation-Sensitizing Agents; Selenium; Selenocysteine; Selenomethionine; Time Factors | 2004 |
Oxidation of thioredoxin reductase in HeLa cells stimulated with tumor necrosis factor-alpha.
Topics: Animals; Apoptosis; Cysteine; Cytoplasm; Disulfides; DNA Fragmentation; Genes, Dominant; HeLa Cells; Humans; Hydrogen Peroxide; Mitochondria, Liver; Mutation; NADP; Oxidation-Reduction; Rats; Recombinant Proteins; Selenocysteine; Thioredoxin Reductase 1; Thioredoxin Reductase 2; Thioredoxin-Disulfide Reductase; Tumor Necrosis Factor-alpha | 2004 |
Identification and synthesis of a novel selenium-sulfur amino acid found in selenized yeast: Rapid indirect detection NMR methods for characterizing low-level organoselenium compounds in complex matrices.
Topics: Chromatography, High Pressure Liquid; Cysteine; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Mass Spectrometry; Organoselenium Compounds; Saccharomyces cerevisiae; Selenium; Selenocysteine | 2004 |
Enhanced 7-ethyl-10-hydroxycamptothecin (SN-38) lethality by methylselenocysteine is associated with Chk2 phosphorylation at threonine-68 and down-regulation of Cdc6 expression.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Carbon-Sulfur Lyases; Caspase 3; Caspases; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Survival; Checkpoint Kinase 1; Checkpoint Kinase 2; Cysteine; DNA Fragmentation; Drug Interactions; Enzyme Activation; Gene Expression; Humans; Irinotecan; Minichromosome Maintenance Complex Component 2; Nuclear Proteins; Organoselenium Compounds; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Kinases; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae Proteins; Selenocysteine | 2004 |
Osteopontin is a potential target gene in mouse mammary cancer chemoprevention by Se-methylselenocysteine.
Topics: Animals; Anticarcinogenic Agents; Caspase 3; Caspases; Cell Division; Cell Movement; Cysteine; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Organoselenium Compounds; Osteopontin; Reverse Transcriptase Polymerase Chain Reaction; Selenocysteine; Sialoglycoproteins; Tumor Cells, Cultured | 2004 |
Insight into the polar reactivity of the onium chalcogen analogues of S-adenosyl-L-methionine.
Topics: Alkylating Agents; Biotransformation; Chalcogens; Cysteine; Escherichia coli; Humans; Methionine; Methionine Adenosyltransferase; Nuclear Magnetic Resonance, Biomolecular; Organoselenium Compounds; Protons; S-Adenosylmethionine; Selenocysteine; Selenomethionine; Stereoisomerism; Substrate Specificity; Sulfonium Compounds; Tellurium | 2004 |
Characterization of the NifS-like domain of ABA3 from Arabidopsis thaliana provides insight into the mechanism of molybdenum cofactor sulfuration.
Topics: Aldehyde Oxidase; Arabidopsis; Arabidopsis Proteins; Bacterial Proteins; Binding Sites; Catalysis; Coenzymes; Cysteine; Cytosol; Fluorescent Dyes; Genetic Vectors; Iron-Sulfur Proteins; Kinetics; Lyases; Lysine; Metalloproteins; Molybdenum; Molybdenum Cofactors; Mutagenesis, Site-Directed; Naphthalenesulfonates; Pichia; Plant Proteins; Protein Binding; Protein Structure, Tertiary; Pteridines; Pyridoxal Phosphate; Selenocysteine; Spectrophotometry; Substrate Specificity; Sulfides; Sulfurtransferases; Xanthine Dehydrogenase | 2005 |
[The apoptosis-inducing activity of human selenoprotein P shorter isoform].
Topics: Animals; Apoptosis; Cloning, Molecular; Cysteine; Escherichia coli; Humans; Ion Channels; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mutation; Protein Isoforms; Proteins; Selenium; Selenocysteine; Selenoprotein P; Selenoproteins | 2004 |
Molecular and biochemical characterization of the selenocysteine Se-methyltransferase gene and Se-methylselenocysteine synthesis in broccoli.
Topics: Amino Acid Sequence; Brassica; Cloning, Molecular; Cysteine; DNA, Complementary; Escherichia coli; Gene Library; Methyltransferases; Molecular Sequence Data; Organoselenium Compounds; Recombinant Proteins; Selenocysteine; Sequence Alignment; Sequence Homology, Amino Acid | 2005 |
Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity.
Topics: Animals; Anions; Antineoplastic Agents; Binding Sites; Cell Nucleus; Curcuma; Curcumin; Cysteine; Cytosol; Dose-Response Relationship, Drug; HeLa Cells; Humans; Inhibitory Concentration 50; Mass Spectrometry; Mitochondria; Models, Biological; Models, Chemical; NADP; NADPH Oxidases; Oxidants; Oxidation-Reduction; Peptides; Plant Extracts; Protein Binding; Rats; Selenocysteine; Superoxides; Temperature; Thioredoxin-Disulfide Reductase; Time Factors | 2005 |
Irinotecan pharmacokinetic and pharmacogenomic alterations induced by methylselenocysteine in human head and neck xenograft tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Carcinoma, Squamous Cell; Cysteine; Female; Head and Neck Neoplasms; Humans; Irinotecan; Mice; Mice, Nude; Organoselenium Compounds; Pharmacogenetics; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Selenocysteine; Transplantation, Heterologous; Tumor Cells, Cultured | 2005 |
Se-methylselenocysteine inhibits phosphatidylinositol 3-kinase activity of mouse mammary epithelial tumor cells in vitro.
Topics: Animals; Anticarcinogenic Agents; Cell Division; Cell Line, Tumor; Cysteine; Enzyme Inhibitors; Epithelial Cells; Mammary Neoplasms, Animal; MAP Kinase Signaling System; Mice; Organoselenium Compounds; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Selenocysteine | 2005 |
Different catalytic mechanisms in mammalian selenocysteine- and cysteine-containing methionine-R-sulfoxide reductases.
Topics: Amino Acid Sequence; Animals; Binding Sites; Catalysis; Conserved Sequence; Cysteine; Dithiothreitol; Evolution, Molecular; Humans; Kinetics; Methionine Sulfoxide Reductases; Molecular Sequence Data; Mutation; Oxidoreductases; Selenocysteine; Sequence Alignment; Thioredoxins | 2005 |
[Effects of selenium and B-27 supplements on viability and differentiation of neural stem cell in newborn rat].
Topics: Animals; Animals, Newborn; Cell Differentiation; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Cysteine; Female; Glial Fibrillary Acidic Protein; Immunohistochemistry; Male; Neurons; Organoselenium Compounds; Rats; Rats, Wistar; Selenium; Selenocysteine; Sodium Selenite; Stem Cells; Tubulin | 2005 |
Inhibition of thioredoxin and thioredoxin reductase by 4-hydroxy-2-nonenal in vitro and in vivo.
Topics: Aldehydes; Binding Sites; Cysteine; Dose-Response Relationship, Drug; HeLa Cells; Humans; Insulin; Kinetics; Oxidation-Reduction; Selenocysteine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thioredoxin-Disulfide Reductase; Thioredoxins | 2006 |
Potentiation of irinotecan sensitivity by Se-methylselenocysteine in an in vivo tumor model is associated with downregulation of cyclooxygenase-2, inducible nitric oxide synthase, and hypoxia-inducible factor 1alpha expression, resulting in reduced angiog
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Carcinoma, Squamous Cell; Cyclooxygenase 2; Cysteine; Down-Regulation; Female; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Irinotecan; Mice; Mice, Nude; Neovascularization, Pathologic; Nitric Oxide Synthase Type II; Organoselenium Compounds; Selenocysteine; Transplantation, Heterologous | 2006 |
Monomethylated selenium inhibits growth of LNCaP human prostate cancer xenograft accompanied by a decrease in the expression of androgen receptor and prostate-specific antigen (PSA).
Topics: Animals; Anticarcinogenic Agents; Cell Line, Tumor; Cell Proliferation; Cysteine; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Nude; Organoselenium Compounds; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Selenium; Selenocysteine; Xenograft Model Antitumor Assays | 2006 |
Se-methylselenocysteine enhances PMA-mediated CD11c expression via phospholipase D1 activation in U937 cells.
Topics: CD11c Antigen; Cell Differentiation; Cysteine; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Organoselenium Compounds; Phospholipase D; Selenocysteine; Tetradecanoylphorbol Acetate; U937 Cells; Up-Regulation | 2006 |
Mechanism for proliferation inhibition by various selenium compounds and selenium-enriched broccoli extract in rat glial cells.
Topics: Animals; Apoptosis; Brassica; Cell Line; Cell Proliferation; Cysteine; DNA Damage; Glutathione Peroxidase; Hydrogen Peroxide; Neuroglia; Organoselenium Compounds; Plant Extracts; Rats; Selenium Compounds; Selenocysteine; Selenomethionine | 2006 |
Studies on deprotection of cysteine and selenocysteine side-chain protecting groups.
Topics: Composite Resins; Cysteine; Disulfides; Oligopeptides; Peptides, Cyclic; Selenocysteine | 2007 |
The mechanism of methylselenocysteine and docetaxel synergistic activity in prostate cancer cells.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cysteine; Docetaxel; Down-Regulation; Drug Synergism; Enzyme Activation; Inhibitor of Apoptosis Proteins; Male; Mice; Microtubule-Associated Proteins; Neoplasm Proteins; Organoselenium Compounds; Prostatic Neoplasms; Selenocysteine; Survivin; Taxoids | 2006 |
Dynamic evolution of selenocysteine utilization in bacteria: a balance between selenoprotein loss and evolution of selenocysteine from redox active cysteine residues.
Topics: Bacteria; Bacterial Proteins; Base Sequence; Cysteine; Evolution, Molecular; Genome, Bacterial; Oxidation-Reduction; Phylogeny; Selenocysteine; Selenoproteins; Sequence Homology, Nucleic Acid | 2006 |
Metabolism of 76Se-methylselenocysteine compared with that of 77Se-selenomethionine and 82Se-selenite.
Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Cysteine; Dietary Supplements; Isotopes; Kidney; Liver; Male; Mass Spectrometry; Organoselenium Compounds; Pancreas; Rats; Rats, Wistar; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; Selenoproteins; Sodium Selenite; Time Factors | 2006 |
Selenium-tolerant diamondback moth disarms hyperaccumulator plant defense.
Topics: Adaptation, Physiological; Animals; Biological Evolution; Brassicaceae; Chromatography, Liquid; Cysteine; Drug Resistance; Genetic Speciation; Mass Spectrometry; Moths; Organoselenium Compounds; Oviposition; Selenocysteine; Spectrum Analysis; Wasps | 2006 |
High-throughput identification of catalytic redox-active cysteine residues.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Archaeal Proteins; Bacterial Proteins; Base Sequence; Catalysis; Computational Biology; Cysteine; Databases, Nucleic Acid; Databases, Protein; Enzymes; Eukaryotic Cells; Evolution, Molecular; Methyltransferases; Molecular Sequence Data; Oxidation-Reduction; Oxidoreductases; Proteins; Selenocysteine; Selenoproteins | 2007 |
Efficacy of increasing the therapeutic index of irinotecan, plasma and tissue selenium concentrations is methylselenocysteine dose dependent.
Topics: Administration, Oral; Animals; Bone Marrow; Camptothecin; Cysteine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Irinotecan; Kidney; Kinetics; Liver; Mice; Mice, Nude; Neoplasms; Organoselenium Compounds; Plasma; Selenium; Selenocysteine | 2007 |
Selenocysteine versus cysteine reactivity: a theoretical study of their oxidation by hydrogen peroxide.
Topics: Chemistry, Physical; Cysteine; Glutathione Peroxidase; Hydrogen Peroxide; Kinetics; Models, Chemical; Models, Molecular; Models, Theoretical; Oxidants; Oxidation-Reduction; Oxygen; Selenocysteine; Software; Thermodynamics | 2007 |
Structural and biochemical studies reveal differences in the catalytic mechanisms of mammalian and Drosophila melanogaster thioredoxin reductases.
Topics: Amino Acid Sequence; Animals; Catalysis; Crystallization; Crystallography, X-Ray; Cysteine; Dithionitrobenzoic Acid; Drosophila melanogaster; Mice; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Selenocysteine; Thioredoxin-Disulfide Reductase | 2007 |
Selenium accumulation protects plants from herbivory by Orthoptera via toxicity and deterrence.
Topics: Animals; Astragalus Plant; Brassicaceae; Cysteine; Ecosystem; Organoselenium Compounds; Orthoptera; Plant Leaves; Selenium; Selenocysteine | 2007 |
Elemental selenium at nano size (Nano-Se) as a potential chemopreventive agent with reduced risk of selenium toxicity: comparison with se-methylselenocysteine in mice.
Topics: Animals; Anticarcinogenic Agents; Biological Availability; Chemical and Drug Induced Liver Injury; Cysteine; Enzymes; Glutathione Transferase; Growth; Indicators and Reagents; Lethal Dose 50; Liver; Malondialdehyde; Mice; Mice, Inbred Strains; Nanoparticles; Nutritional Physiological Phenomena; Organoselenium Compounds; Selenium; Selenocysteine; Survival Analysis | 2008 |
Influence of pH and flanking serine on the redox potential of S-S and S-Se bridges of Cys-Cys and Cys-Sec peptides.
Topics: Cysteine; Disulfides; Hydrogen-Ion Concentration; Oxidation-Reduction; Peptides; Selenium; Selenocysteine; Serine | 2007 |
Selenium methylselenocysteine protects human hepatoma HepG2 cells against oxidative stress induced by tert-butyl hydroperoxide.
Topics: Anticarcinogenic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cysteine; Glutathione; Humans; Liver Neoplasms; Malondialdehyde; Organoselenium Compounds; Oxidative Stress; Reactive Oxygen Species; Selenocysteine; tert-Butylhydroperoxide; Time Factors | 2007 |
Preferential organ distribution of methylselenol source Se-methylselenocysteine relative to methylseleninic acid.
Topics: Animals; Chromatography, High Pressure Liquid; Cysteine; Male; Mass Spectrometry; Organoselenium Compounds; Rats; Reference Standards; Selenocysteine; Tissue Distribution | 2008 |
Subchronic oral toxicity studies of Se-methylselenocysteine, an organoselenium compound for breast cancer prevention.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Breast Neoplasms; Cysteine; Dogs; Female; Liver; Male; Organoselenium Compounds; Rats; Selenocysteine | 2008 |
[Effects of Se-methylselenocysteine on biological behavior of and matrix metalloproteinase-2 expression in human breast cancer MDA-MB-231 cells].
Topics: Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cysteine; Female; Humans; Matrix Metalloproteinase 2; Organoselenium Compounds; RNA, Messenger; S Phase; Selenocysteine | 2008 |
Reduced reliance on the trace element selenium during evolution of mammals.
Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Cysteine; Evolution, Molecular; Fishes; Gene Expression; Humans; Molecular Sequence Data; Nematoda; Protein Disulfide Reductase (Glutathione); Protein Structure, Tertiary; Proteome; Selenium; Selenocysteine; Selenoprotein P; Thioredoxins; Trace Elements | 2008 |
Se-methylselenocysteine alters collagen gene and protein expression in human prostate cells.
Topics: Cell Line, Tumor; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type IV; Collagen Type VI; Collagen Type VII; Cysteine; Gene Expression; Humans; Male; Organoselenium Compounds; Prostate; RNA, Messenger; Selenocysteine; Sodium Selenite | 2008 |
Differential sensitivity of various human tumour-derived cell types to apoptosis by organic derivatives of selenium.
Topics: Adenocarcinoma; Adolescent; Adult; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cysteine; Epithelial Cells; Female; Humans; Liver Neoplasms; Male; Melanoma; Middle Aged; Neoplasms; Neuroectodermal Tumors, Primitive, Peripheral; Organoselenium Compounds; Selenium Compounds; Selenocysteine; Selenomethionine; Skin Neoplasms | 2009 |
Tumor vascular maturation and improved drug delivery induced by methylselenocysteine leads to therapeutic synergy with anticancer drugs.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Capillary Permeability; Carcinoma, Squamous Cell; Cysteine; Drug Delivery Systems; Drug Synergism; Female; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Neovascularization, Pathologic; Organoselenium Compounds; Selenocysteine; Xenograft Model Antitumor Assays | 2008 |
Hypoxia-specific drug tirapazamine does not abrogate hypoxic tumor cells in combination therapy with irinotecan and methylselenocysteine in well-differentiated human head and neck squamous cell carcinoma a253 xenografts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Squamous Cell; Cell Differentiation; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cysteine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Forkhead Transcription Factors; Head and Neck Neoplasms; Humans; Irinotecan; Maximum Tolerated Dose; Mice; Mice, Nude; Neoplasm Transplantation; Organoselenium Compounds; Selenocysteine; Tirapazamine; Triazines; Xenograft Model Antitumor Assays | 2008 |
Long exposure of non-cytotoxic concentrations of methylselenol suppresses the invasive potential of B16F10 melanoma.
Topics: Animals; Cell Adhesion; Cell Movement; Cell Survival; Cysteine; Dietary Supplements; Female; Fibronectins; Flow Cytometry; Gelatinases; Humans; Integrin alphaVbeta3; Integrins; Lung Neoplasms; Melanoma, Experimental; Methanol; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Organoselenium Compounds; Selenocysteine; Sodium Selenite; Survival Rate; Tumor Cells, Cultured; Vitronectin; Wound Healing | 2008 |
An anaerobic bacterial MsrB model reveals catalytic mechanisms, advantages, and disadvantages provided by selenocysteine and cysteine in reduction of methionine-R-sulfoxide.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Catalytic Domain; Cell Line; Clostridium; Cysteine; Dithiothreitol; DNA Primers; Humans; Kinetics; Methionine; Methionine Sulfoxide Reductases; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidoreductases; Recombinant Proteins; Selenocysteine; Sequence Homology, Amino Acid; Thioredoxins | 2008 |
Mitochondria-targeted chemotherapeutics: the rational design of gold(I) N-heterocyclic carbene complexes that are selectively toxic to cancer cells and target protein selenols in preference to thiols.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cysteine; Drug Design; Drug Screening Assays, Antitumor; Gold; Heterocyclic Compounds; Humans; Methane; Mitochondria; Mitochondrial Proteins; Organometallic Compounds; Selenocysteine; Thioredoxin-Disulfide Reductase | 2008 |
Selenocysteine incorporation in Kinetoplastid: selenophosphate synthetase (SELD) from Leishmania major and Trypanosoma brucei.
Topics: Amino Acid Sequence; Animals; Cloning, Molecular; Cysteine; Genetic Complementation Test; Leishmania major; Molecular Sequence Data; Phosphotransferases; Protozoan Proteins; Selenocysteine; Sequence Alignment; Trypanosoma brucei brucei | 2008 |
Combination of methylselenocysteine with tamoxifen inhibits MCF-7 breast cancer xenografts in nude mice through elevated apoptosis and reduced angiogenesis.
Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cell Division; Cyclin D1; Cysteine; Drug Synergism; Estradiol; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Neovascularization, Pathologic; Organoselenium Compounds; Random Allocation; Receptors, Progesterone; Selenocysteine; Specific Pathogen-Free Organisms; Tamoxifen; Xenograft Model Antitumor Assays | 2009 |
Dietary supplementation with selenomethylselenocysteine produces a differential proteomic response.
Topics: Animals; Cysteine; Dietary Supplements; Electrophoresis, Gel, Two-Dimensional; Female; Male; Organoselenium Compounds; Proteomics; Rats; Rats, Wistar; Selenium; Selenocysteine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2009 |
Selenocysteine positional variants reveal contributions to copper binding from cysteine residues in domains 2 and 3 of human copper chaperone for superoxide dismutase.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Copper; Cysteine; Humans; Molecular Chaperones; Molecular Sequence Data; Mutation; Protein Multimerization; Protein Structure, Tertiary; Selenocysteine; Spectrum Analysis; Sulfhydryl Compounds; Superoxide Dismutase | 2008 |
Differential action of methylselenocysteine in control and alloxan-diabetic rabbits.
Topics: Albuminuria; Animals; Blood Glucose; Body Weight; Creatinine; Cysteine; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Kidney; Kidney Diseases; Liver; Male; Necrosis; Organoselenium Compounds; Oxidoreductases; Rabbits; Selenium; Selenocysteine; Urea | 2009 |
Accumulation of an organic anticancer selenium compound in a transgenic Solanaceous species shows wider applicability of the selenocysteine methyltransferase transgene from selenium hyperaccumulators.
Topics: Anticarcinogenic Agents; Cysteine; Methyltransferases; Nicotiana; Organoselenium Compounds; Plant Proteins; Plants, Genetically Modified; Selenocysteine; Sulfate Adenylyltransferase; Transgenes | 2009 |
Separation and determination of seleno amino acids using gas chromatography hyphenated with inductively coupled plasma mass spectrometry after hollow fiber liquid phase microextraction.
Topics: Agaricales; Brassica; Chemical Fractionation; Chloroform; Cysteine; Ethionine; Garlic; Gas Chromatography-Mass Spectrometry; Organoselenium Compounds; Selenocysteine; Selenomethionine; Sensitivity and Specificity; Sodium Chloride; Toluene | 2009 |
Chemopreventive doses of methylselenocysteine alter circadian rhythm in rat mammary tissue.
Topics: Animals; Breast Neoplasms; Carcinoma; Cell Cycle Proteins; Chemoprevention; Circadian Rhythm; Cysteine; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Mammary Glands, Animal; Methylnitrosourea; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Organoselenium Compounds; Period Circadian Proteins; Rats; Rats, Inbred F344; Selenium; Selenocysteine; Specific Pathogen-Free Organisms | 2008 |
Genetic code supports targeted insertion of two amino acids by one codon.
Topics: 3' Untranslated Regions; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Codon; Codon, Terminator; Cysteine; Euplotes; Genetic Code; Humans; Molecular Sequence Data; Mutation; Protozoan Proteins; Recombinant Fusion Proteins; RNA, Protozoan; RNA, Transfer, Amino Acid-Specific; RNA, Transfer, Cys; Selenocysteine; Selenoproteins | 2009 |
Integrated oxidative folding of cysteine/selenocysteine containing peptides: improving chemical synthesis of conotoxins.
Topics: Conotoxins; Cysteine; Disulfides; Magnetic Resonance Spectroscopy; Peptides; Protein Folding; Selenocysteine | 2009 |
Selenium metabolism in rats with long-term ingestion of Se-methylselenocysteine using enriched stable isotopes.
Topics: Animals; Cysteine; Isotopes; Kidney; Liver; Male; Organoselenium Compounds; Rats; Rats, Wistar; Selenium; Selenocysteine; Tissue Distribution | 2009 |
Penultimate selenocysteine residue replaced by cysteine in thioredoxin reductase from selenium-deficient rat liver.
Topics: Amino Acid Sequence; Animals; Codon, Terminator; Cysteine; Feedback, Physiological; Glutaredoxins; Liver; Male; Models, Biological; Rats; Rats, Sprague-Dawley; RNA, Messenger; Selenium; Selenocysteine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thioredoxin Reductase 1; Thioredoxins | 2009 |
Se-methylselenocysteine sensitized TRAIL-mediated apoptosis via down-regulation of Bcl-2 expression.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma; Caspases; Cysteine; Down-Regulation; Drug Evaluation, Preclinical; Drug Synergism; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Kidney Neoplasms; Organoselenium Compounds; Peptide Fragments; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Selenocysteine; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured | 2009 |
Further development of new deprotection chemistry for cysteine and selenocysteine side chain protecting groups.
Topics: Amino Acid Sequence; Cysteine; Selenocysteine | 2009 |
Methyl-selenium compounds inhibit prostate carcinogenesis in the transgenic adenocarcinoma of mouse prostate model with survival benefit.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Proliferation; Cysteine; Enzyme-Linked Immunosorbent Assay; In Situ Nick-End Labeling; Insulin-Like Growth Factor I; Male; Mice; Mice, Transgenic; Organoselenium Compounds; Prostatic Neoplasms; Selenocysteine; Selenomethionine | 2009 |
Antiproliferative effects of selenium compounds in colon cancer cells: comparison of different cytotoxicity assays.
Topics: Anticarcinogenic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cysteine; Cytotoxins; Humans; Methionine; Organoselenium Compounds; Selenocysteine; Sodium Selenite; Toxicity Tests | 2009 |
Expressed protein ligation for metalloprotein design and engineering.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Azurin; Bacterial Proteins; Binding Sites; Copper; Cysteine; Electron Spin Resonance Spectroscopy; Inteins; Ligands; Metalloproteins; Methionine; Molecular Sequence Data; Peptides; Protein Engineering; Protein Splicing; Pseudomonas aeruginosa; Recombinant Fusion Proteins; Selenocysteine; Spectrophotometry | 2009 |
Inhibition of colon cancer growth by methylselenocysteine-induced angiogenic chemomodulation is influenced by histologic characteristics of the tumor.
Topics: Animals; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Cell Differentiation; Colon; Colorectal Neoplasms; Cysteine; Doxorubicin; Drug Delivery Systems; Drug Resistance, Neoplasm; Female; Humans; Hypoxia; Immunoenzyme Techniques; Magnetic Resonance Imaging; Mice; Mice, Nude; Neovascularization, Pathologic; Organoselenium Compounds; Selenocysteine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2009 |
Speciation analysis of selenium metabolites in urine and breath by HPLC- and GC-inductively coupled plasma-MS after administration of selenomethionine and methylselenocysteine to rats.
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Cysteine; Exhalation; Gas Chromatography-Mass Spectrometry; Male; Organoselenium Compounds; Rats; Rats, Wistar; Selenium Compounds; Selenocysteine; Selenomethionine | 2009 |
Organic and inorganic selenium compounds produce different protein patterns in the blood plasma of rats.
Topics: Animals; Blood Proteins; Cysteine; Dietary Supplements; Electrophoresis, Gel, Two-Dimensional; Male; Mass Spectrometry; Organoselenium Compounds; Rats; Rats, Wistar; Selenic Acid; Selenium; Selenium Compounds; Selenocysteine | 2009 |
In vitro radioprotection studies of organoselenium compounds: differences between mono- and diselenides.
Topics: Animals; Cattle; Cell Line, Tumor; Cysteine; Cystine; DNA; DNA Damage; Gamma Rays; Lipid Peroxidation; Liposomes; Lymphocytes; Lymphoma; Mice; Mice, Inbred C57BL; Organoselenium Compounds; Protein Carbonylation; Radiation-Protective Agents; Selenocysteine; Selenomethionine; Serum Albumin, Bovine; Thiobarbituric Acid Reactive Substances; Thymus Neoplasms | 2009 |
Speciation of selenium dietary supplements; formation of S-(methylseleno)cysteine and other selenium compounds.
Topics: Chromatography, High Pressure Liquid; Cysteine; Dietary Supplements; Gas Chromatography-Mass Spectrometry; Organoselenium Compounds; Selenium Compounds; Selenocysteine; Spectrometry, Mass, Electrospray Ionization; Temperature | 2009 |
Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.
Topics: Antitubercular Agents; Cysteine; Drug Evaluation, Preclinical; Mycobacterium; Mycobacterium smegmatis; Organoselenium Compounds; Selenocysteine; Small Molecule Libraries | 2009 |
Differential apoptotic response of human cancer cells to organoselenium compounds.
Topics: Anticarcinogenic Agents; Apoptosis; Blotting, Western; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Flow Cytometry; Humans; Neoplasms; Organoselenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite; Tumor Suppressor Protein p53 | 2010 |
Selenocysteine is selectively taken up by red blood cells.
Topics: Absorption; Animals; Biological Transport; Cysteine; Erythrocytes; Hemoglobins; Male; Rats; Rats, Wistar; Selenocysteine; Sodium Azide | 2009 |
Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1alpha.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Cysteine; Drug Delivery Systems; Female; Gene Knockdown Techniques; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Irinotecan; Mice; Mice, Nude; Organoselenium Compounds; Reactive Oxygen Species; RNA, Small Interfering; Selenocysteine; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2010 |
Interleukin-10 delivery via mesenchymal stem cells: a novel gene therapy approach to prevent lung ischemia-reperfusion injury.
Topics: Animals; Bronchoalveolar Lavage Fluid; Caspase 3; Cysteine; Genetic Therapy; Genetic Vectors; Hematopoietic Stem Cells; Interleukin-10; Lung; Lung Transplantation; Male; Mesenchymal Stem Cells; Organoselenium Compounds; Rats; Rats, Inbred Lew; Reperfusion Injury; Selenocysteine | 2010 |
Selenium compounds activate early barriers of tumorigenesis.
Topics: Anticarcinogenic Agents; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cellular Senescence; Cysteine; DNA Damage; DNA Repair; DNA-Binding Proteins; Histones; Humans; Male; Neoplasms; Organoselenium Compounds; Oxidative Stress; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Selenium Compounds; Selenocysteine; Sodium Selenite; Tumor Suppressor Proteins | 2010 |
Methylselenocysteine resets the rhythmic expression of circadian and growth-regulatory genes disrupted by nitrosomethylurea in vivo.
Topics: Administration, Oral; Alkylating Agents; Animals; Anticarcinogenic Agents; Blotting, Western; Cell Proliferation; Circadian Rhythm; Cysteine; Diet; Female; Gene Expression; Gene Expression Regulation; Immunohistochemistry; Mammary Glands, Animal; Methylnitrosourea; Organoselenium Compounds; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Selenocysteine | 2010 |
Anti-hemolytic and peroxyl radical scavenging activity of organoselenium compounds: an in vitro study.
Topics: Cysteine; Cystine; Erythrocytes; Free Radical Scavengers; Hemolysis; Humans; Lipid Peroxidation; Organoselenium Compounds; Oxidation-Reduction; Peroxides; Selenocysteine; Selenomethionine | 2011 |
Selenium, but not lycopene or vitamin E, decreases growth of transplantable dunning R3327-H rat prostate tumors.
Topics: Androgens; Animals; Carotenoids; Cell Proliferation; Cysteine; Lycopene; Male; Neoplasm Transplantation; Organoselenium Compounds; Prostatic Neoplasms; Rats; Selenium; Selenocysteine; Tumor Burden; Vitamin E | 2010 |
p-Nitrobenzyl protection for cysteine and selenocysteine: a more stable alternative to the acetamidomethyl group.
Topics: Cysteine; Nitrobenzenes; Oxidation-Reduction; Oxytocin; Selenocysteine | 2010 |
The von Hippel-Lindau (VHL) tumor-suppressor gene is down-regulated by selenium deficiency in Caco-2 cells and rat colon mucosa.
Topics: Animals; Caco-2 Cells; Cell Line, Tumor; Colon; Cysteine; DNA Methylation; Glutathione Peroxidase; Humans; Liver; Male; Mucous Membrane; Organoselenium Compounds; Promoter Regions, Genetic; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Selenium; Selenocysteine; Von Hippel-Lindau Tumor Suppressor Protein | 2011 |
Proteomic profiling of potential molecular targets of methyl-selenium compounds in the transgenic adenocarcinoma of mouse prostate model.
Topics: Adenocarcinoma; Animals; Biomarkers, Pharmacological; Biomarkers, Tumor; Cysteine; Disease Models, Animal; Male; Metabolome; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Organoselenium Compounds; Prostatic Neoplasms; Proteomics; Selenium Compounds; Selenocysteine; Selenomethionine | 2010 |
Survivin gene silencing sensitizes prostate cancer cells to selenium growth inhibition.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cysteine; Down-Regulation; Drug Synergism; Gene Silencing; Humans; Immunoenzyme Techniques; Inhibitor of Apoptosis Proteins; Male; Mice; Mice, Nude; Neoplasms, Hormone-Dependent; Organoselenium Compounds; Prognosis; Prostatic Neoplasms; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selenocysteine; Survival Rate; Survivin | 2010 |
Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells.
Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Anticarcinogenic Agents; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; Colorectal Neoplasms; Cysteine; DNA Breaks; DNA Mismatch Repair; DNA Repair Enzymes; DNA-Binding Proteins; Drug Resistance, Neoplasm; Guanosine; Humans; Mismatch Repair Endonuclease PMS2; Morpholines; MutL Protein Homolog 1; Nuclear Proteins; Organoselenium Compounds; Piperidines; Protein Serine-Threonine Kinases; Pyrones; Reactive Oxygen Species; Selenocysteine; Sodium Selenite; Tumor Suppressor Proteins | 2010 |
Traceless ligation of cysteine peptides using selective deselenization.
Topics: Alanine; Amino Acid Sequence; Cysteine; Peptides; Phosphines; Selenocysteine | 2010 |
Simultaneous analysis of mercury and selenium species including chiral forms of selenomethionine in human urine and serum by HPLC column-switching coupled to ICP-MS.
Topics: Chromatography, High Pressure Liquid; Cysteine; Cystine; Dietary Supplements; Humans; Mass Spectrometry; Mercury; Methylmercury Compounds; Organoselenium Compounds; Selenic Acid; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite; Stereoisomerism | 2010 |
Selenium hyperaccumulation offers protection from cell disruptor herbivores.
Topics: Animals; Astragalus Plant; Brassicaceae; Cysteine; Food Preferences; Insecta; Organoselenium Compounds; Selenium; Selenocysteine; Tetranychidae | 2010 |
Effects of selenite and chelating agents on mammalian thioredoxin reductase inhibited by mercury: implications for treatment of mercury poisoning.
Topics: Animals; Biocatalysis; Catalytic Domain; Cell Survival; Chelating Agents; Cysteine; Dose-Response Relationship, Drug; Enzyme Activation; Glutathione; HEK293 Cells; Humans; Mercuric Chloride; Mercury; Mercury Compounds; Mercury Poisoning; Methylmercury Compounds; Molecular Structure; NADP; Rats; Recombinant Proteins; Selenium Compounds; Selenocysteine; Sodium Selenite; Spectrometry, Mass, Electrospray Ionization; Thioredoxin-Disulfide Reductase | 2011 |
Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery.
Topics: Animals; Codon, Terminator; Cysteine; Diet; Isoenzymes; Liver; Mice; Mice, Inbred C57BL; Mutagenesis, Insertional; NIH 3T3 Cells; Phosphates; RNA, Transfer, Amino Acyl; Selenium; Selenocysteine; Thioredoxin Reductase 1; Transferases | 2010 |
Chemical form of selenium affects its uptake, transport, and glutathione peroxidase activity in the human intestinal Caco-2 cell model.
Topics: Alanine; Caco-2 Cells; Cysteine; Enzyme Activation; Glutathione Peroxidase; Humans; Organoselenium Compounds; Selenium; Selenocysteine; Sodium Selenite | 2011 |
Se-methylselenocysteine inhibits lipopolysaccharide-induced NF-κB activation and iNOS induction in RAW 264.7 murine macrophages.
Topics: Animals; Anticarcinogenic Agents; Cells, Cultured; Cysteine; Enzyme Induction; I-kappa B Proteins; Lipopolysaccharides; Macrophages; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; Organoselenium Compounds; Phosphorylation; RNA, Messenger; Selenocysteine | 2011 |
Uptake, distribution, and speciation of selenoamino acids by human cancer cells: X-ray absorption and fluorescence methods.
Topics: Cell Line, Tumor; Cysteine; Humans; Microscopy, Fluorescence; Neoplasms; Organoselenium Compounds; Selenocysteine; Selenomethionine; X-Ray Absorption Spectroscopy | 2011 |
Bioinorganic and medicinal chemistry: aspects of gold(I)-protein complexes.
Topics: Arthritis, Rheumatoid; Binding Sites; Catalytic Domain; Chemistry, Pharmaceutical; Coordination Complexes; Cysteine; Glutathione Reductase; Gold; Humans; Protein Tyrosine Phosphatases; Proteins; Selenocysteine; Serum Albumin | 2011 |
Lobe-specific lineages of carcinogenesis in the transgenic adenocarcinoma of mouse prostate and their responses to chemopreventive selenium.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Cell Lineage; Cysteine; Disease Models, Animal; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Metastasis; Organoselenium Compounds; Prostatic Neoplasms; Proteomics; Selenocysteine; Seminal Vesicles | 2011 |
Magnetic resonance and fluorescence-protein imaging of the anti-angiogenic and anti-tumor efficacy of selenium in an orthotopic model of human colon cancer.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Cysteine; Diagnostic Imaging; Female; Green Fluorescent Proteins; Humans; Magnetic Resonance Imaging; Mice; Mice, Nude; Microvessels; Neovascularization, Pathologic; Organoselenium Compounds; Random Allocation; Selenocysteine; Xenograft Model Antitumor Assays | 2011 |
Identification and conformer analysis of a novel redox-active motif, Pro-Ala-Ser-Cys-Cys-Ser, in Drosophila thioredoxin reductase by semiempirical molecular orbital calculation.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Biocatalysis; Cysteine; Drosophila melanogaster; Escherichia coli; Humans; Kinetics; Lung; Models, Molecular; Molecular Sequence Data; Mutation; Oxidation-Reduction; Recombinant Proteins; Selenium; Selenocysteine; Sequence Homology, Amino Acid; Thioredoxin-Disulfide Reductase | 2011 |
Metabolic and bioprocess engineering for production of selenized yeast with increased content of seleno-methylselenocysteine.
Topics: Astragalus Plant; Cysteine; Genetic Engineering; Methyltransferases; Organoselenium Compounds; Plant Proteins, Dietary; Recombinant Proteins; Saccharomyces cerevisiae; Selenocysteine | 2011 |
Cysteine mutant of mammalian GPx4 rescues cell death induced by disruption of the wild-type selenoenzyme.
Topics: Animals; Biocatalysis; Blotting, Western; Cell Hypoxia; Cell Proliferation; Cell Survival; Cells, Cultured; Cysteine; Doxycycline; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutant Proteins; Mutation; Phospholipid Hydroperoxide Glutathione Peroxidase; Reverse Transcriptase Polymerase Chain Reaction; Selenocysteine; Selenoproteins; Tamoxifen | 2011 |
Susceptibility of the antioxidant selenoenyzmes thioredoxin reductase and glutathione peroxidase to alkylation-mediated inhibition by anticancer acylfulvenes.
Topics: Agaricales; Alkylation; Antineoplastic Agents; Antioxidants; Cell Survival; Cysteine; Enzyme Inhibitors; Glutathione Peroxidase; HeLa Cells; Humans; Neoplasms; Polycyclic Sesquiterpenes; Selenocysteine; Sesquiterpenes; Spiro Compounds; Thioredoxin-Disulfide Reductase | 2011 |
Mouse prostate proteomes are differentially altered by supranutritional intake of four selenium compounds.
Topics: Animals; Anticarcinogenic Agents; Cysteine; Gene Expression Profiling; Gene Expression Regulation; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Organoselenium Compounds; Prostate; Prostatic Neoplasms; Protein Biosynthesis; Proteomics; RNA, Messenger; Selenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite; Xenograft Model Antitumor Assays | 2011 |
Distribution of Se and its species in Myriophyllum spicatum and Ceratophyllum demersum growing in water containing Se (VI).
Topics: Chlorophyll; Chlorophyll A; Chromatography, High Pressure Liquid; Cysteine; Cystine; Magnoliopsida; Mass Spectrometry; Organoselenium Compounds; Photosystem II Protein Complex; Selenic Acid; Selenium Compounds; Selenocysteine; Selenomethionine; Water | 2011 |
Augmented therapeutic efficacy of irinotecan is associated with enhanced drug accumulation.
Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Chromatography, High Pressure Liquid; Cysteine; Drug Synergism; Female; Humans; Immunohistochemistry; Irinotecan; Mice; Mice, Nude; Neoplasms, Experimental; Organoselenium Compounds; Selenocysteine; Xenograft Model Antitumor Assays | 2011 |
Biofortification of tomato (Solanum lycopersicum) fruit with the anticancer compound methylselenocysteine using a selenocysteine methyltransferase from a selenium hyperaccumulator.
Topics: Antineoplastic Agents; Cysteine; Food, Fortified; Fruit; Gene Expression; Methyltransferases; Organoselenium Compounds; Plants, Genetically Modified; Selenic Acid; Selenium; Selenium Compounds; Selenocysteine; Sodium Selenite; Solanum lycopersicum | 2011 |
Analysis of selenomethylselenocysteine and selenomethionine by LC-ESI-MS/MS with diethyl ethoxymethylenemalonate derivatization.
Topics: Chromatography, High Pressure Liquid; Cysteine; Malonates; Mercaptoethanol; Onions; Organoselenium Compounds; Oxidation-Reduction; Selenocysteine; Selenomethionine; Spectrometry, Mass, Electrospray Ionization | 2011 |
On the mechanism and rate of gold incorporation into thiol-dependent flavoreductases.
Topics: Animals; Auranofin; Cysteine; Gold; Molecular Structure; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Protein Structure, Secondary; Schistosoma mansoni; Selenocysteine | 2012 |
Methylselenocysteine treatment leads to diselenide formation in human cancer cells: evidence from X-ray absorption spectroscopy studies.
Topics: Antineoplastic Agents; Benzene Derivatives; Cell Line, Tumor; Cysteine; Humans; Organoselenium Compounds; Selenium Compounds; Selenocysteine; X-Ray Absorption Spectroscopy | 2012 |
Selenium is a modulator of circadian clock that protects mice from the toxicity of a chemotherapeutic drug via upregulation of the core clock protein, BMAL1.
Topics: Animals; ARNTL Transcription Factors; Cell Line, Tumor; Circadian Clocks; CLOCK Proteins; Cyclophosphamide; Cysteine; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Neoplasms; Organoselenium Compounds; Period Circadian Proteins; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Selenium Compounds; Selenocysteine; Transcription Factors; Transcription, Genetic; Transcriptional Activation | 2011 |
A bioinformatics approach to characterize mammalian selenoprotein T.
Topics: Amino Acid Sequence; Animals; Cell Membrane; Computational Biology; Conserved Sequence; Cysteine; Endoplasmic Reticulum; Humans; Mammals; Membrane Proteins; Mitochondria; Molecular Sequence Data; Nucleic Acid Conformation; Oxidation-Reduction; Protein Folding; Protein Structure, Tertiary; Protein Transport; Selenocysteine; Selenoproteins; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship; Thioredoxins | 2012 |
Going non-native to improve oxidative protein folding.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Circular Dichroism; Cysteine; Disulfides; Kinetics; Oxidation-Reduction; Protein Folding; Selenium; Selenocysteine; Trypsin Inhibitors | 2012 |
Dissecting a role of evolutionary-conserved but noncritical disulfide bridges in cysteine-rich peptides using ω-conotoxin GVIA and its selenocysteine analogs.
Topics: Amino Acid Sequence; Cysteine; Disulfides; Evolution, Chemical; Models, Molecular; Molecular Sequence Data; omega-Conotoxin GVIA; Peptides; Protein Folding; Proteolysis; Selenocysteine; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2012 |
Thiophosphate and selenite conversely modulate cell death induced by glutathione depletion or cisplatin: effects related to activity and Sec contents of thioredoxin reductase.
Topics: Animals; Cell Death; Cell Line, Tumor; Cisplatin; Cysteine; Dinitrochlorobenzene; Glutathione; HCT116 Cells; Humans; Mice; NIH 3T3 Cells; Phosphates; Rats; Selenocysteine; Sodium Selenite; Thioredoxin Reductase 1 | 2012 |
Protein folding: Turbo-charged crosslinking.
Topics: Cysteine; Kinetics; Oxidation-Reduction; Protein Folding; Proteins; Selenocysteine | 2012 |
(77)Se enrichment of proteins expands the biological NMR toolbox.
Topics: Catalysis; Crystallography, X-Ray; Cysteine; Cytochrome Reductases; Flavins; Humans; Magnetic Resonance Spectroscopy; Mutation; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors; Protein Conformation; Protein Folding; Selenocysteine; Selenomethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2013 |
An enzymatic route to selenazolines.
Topics: Amino Acid Sequence; Cysteine; Iodoacetamide; Multienzyme Complexes; Oxazoles; Peptides, Cyclic; Selenium; Selenocysteine; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazoles; Threonine | 2013 |
Selective metabolism of hypothiocyanous acid by mammalian thioredoxin reductase promotes lung innate immunity and antioxidant defense.
Topics: Amino Acid Substitution; Animals; Antioxidants; Auranofin; Bacterial Proteins; Bronchioles; Cell Survival; Cells, Cultured; Cysteine; Epithelial Cells; Humans; Hypochlorous Acid; Immunity, Innate; Kinetics; Lung; Mice; Microbial Viability; Rats; Selenocysteine; Substrate Specificity; Thiocyanates; Thioredoxin-Disulfide Reductase | 2013 |
Effect of exchange of the cysteine molybdenum ligand with selenocysteine on the structure and function of the active site in human sulfite oxidase.
Topics: Catalytic Domain; Coenzymes; Cysteine; Electron Spin Resonance Spectroscopy; Humans; Hydrogen-Ion Concentration; Kinetics; Ligands; Metalloproteins; Molybdenum; Molybdenum Cofactors; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Selenocysteine; X-Ray Absorption Spectroscopy | 2013 |
Bio-inspired band gap engineering of zinc oxide by intracrystalline incorporation of amino acids.
Topics: Amino Acids; Arginine; Biomimetic Materials; Crystallization; Cysteine; Feasibility Studies; Glutamic Acid; Microscopy, Electrochemical, Scanning; Nitrogen; Photoelectron Spectroscopy; Selenocysteine; Semiconductors; Serine; X-Ray Diffraction; Zinc Oxide | 2014 |
The cysteine desulfurase IscS of Mycobacterium tuberculosis is involved in iron-sulfur cluster biogenesis and oxidative stress defence.
Topics: Apoproteins; Bacterial Proteins; Carbon-Sulfur Lyases; Catalytic Domain; Crystallography, X-Ray; Cysteine; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Iron-Sulfur Proteins; Models, Molecular; Mycobacterium tuberculosis; Operon; Oxidative Stress; Phylogeny; Protein Conformation; Recombinant Proteins; Selenocysteine; Substrate Specificity; Two-Hybrid System Techniques | 2014 |
Resolution of oxidative stress by thioredoxin reductase: Cysteine versus selenocysteine.
Topics: Animals; Cell Survival; Cysteine; Epithelial Cells; Glucose Oxidase; Humans; Hydrogen Peroxide; Lung; Mice; Oxidative Stress; Peroxiredoxins; Selenocysteine; Thioredoxin Reductase 1; Thioredoxin Reductase 2; Vitamin K 3 | 2014 |
Characterization and structural analysis of human selenium-dependent glutathione peroxidase 4 mutant expressed in Escherichia coli.
Topics: Cloning, Molecular; Cysteine; Escherichia coli; Gene Expression; Glutathione Peroxidase; Humans; Models, Molecular; Mutation; Phospholipid Hydroperoxide Glutathione Peroxidase; Plasmids; Protein Engineering; Recombinant Proteins; Selenocysteine; Serine | 2014 |
A comprehensive one-pot synthesis of protected cysteine and selenocysteine SPPS derivatives.
Topics: Cysteine; Peptides; Selenocysteine; Solid-Phase Synthesis Techniques | 2014 |
Why selenocysteine replaces cysteine in thioredoxin reductase: a radical hypothesis.
Topics: Catalytic Domain; Cysteine; Models, Chemical; Protein Binding; Selenium; Selenocysteine; Sulfur; Thermodynamics; Thioredoxin-Disulfide Reductase | 2014 |
Engineering the elongation factor Tu for efficient selenoprotein synthesis.
Topics: Asparagine; Bacterial Proteins; Binding Sites; Catalytic Domain; Cysteine; Humans; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Peptide Elongation Factor Tu; Protein Biosynthesis; Protein Engineering; RNA, Transfer, Amino Acid-Specific; Selenocysteine; Selenoproteins | 2014 |
Kynurenine aminotransferase III and glutamine transaminase L are identical enzymes that have cysteine S-conjugate β-lyase activity and can transaminate L-selenomethionine.
Topics: Alkenes; Animals; Carbon-Sulfur Lyases; Cysteine; Histone Deacetylase Inhibitors; Humans; Kinetics; Liver; Mice; Neoplasms; Recombinant Proteins; Selenocysteine; Selenomethionine; Substrate Specificity; Tandem Mass Spectrometry; Transaminases | 2014 |
Cysteine transport through excitatory amino acid transporter 3 (EAAT3).
Topics: Animals; Cysteine; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamic Acid; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Oocytes; Selenocysteine; Xenopus | 2014 |
Characterization of the UGA-recoding and SECIS-binding activities of SECIS-binding protein 2.
Topics: 3' Untranslated Regions; Amino Acid Sequence; Animals; Cell Line, Tumor; Codon, Terminator; Cysteine; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Protein Binding; Protein Biosynthesis; Rats; Recombinant Proteins; RNA-Binding Proteins; RNA, Messenger; Selenocysteine; Selenoproteins; Sequence Homology, Amino Acid | 2014 |
Site-Specific Dual Antibody Conjugation via Engineered Cysteine and Selenocysteine Residues.
Topics: Cell Line, Tumor; Cysteine; Humans; Immunoconjugates; Selenocysteine; Trastuzumab | 2015 |
Oxidative Deselenization of Selenocysteine: Applications for Programmed Ligation at Serine.
Topics: Amino Acid Sequence; Animals; Cysteine; Glycopeptides; Hirudo medicinalis; Humans; Molecular Sequence Data; Mucin 5AC; Mucin-4; Oxidation-Reduction; Proteins; Selenocysteine | 2015 |
Regulation of Selenocysteine Content of Human Selenoprotein P by Dietary Selenium and Insertion of Cysteine in Place of Selenocysteine.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cysteine; Diet; Hep G2 Cells; Humans; Molecular Sequence Data; Phosphates; Selenious Acid; Selenium; Selenocysteine; Selenoprotein P | 2015 |
Details in the catalytic mechanism of mammalian thioredoxin reductase 1 revealed using point mutations and juglone-coupled enzyme activities.
Topics: Amino Acids; Catalysis; Cysteine; Humans; Mutation; NADPH Oxidases; Naphthoquinones; Oxidation-Reduction; Point Mutation; Selenocysteine; Substrate Specificity; Superoxides; Thioredoxin Reductase 1 | 2016 |
Inhibitory nitrosylation of mammalian thioredoxin reductase 1: Molecular characterization and evidence for its functional role in cellular nitroso-redox imbalance.
Topics: Amino Acid Sequence; Animals; Catalytic Domain; Cysteine; Glutathione; HeLa Cells; Humans; NADP; Nitric Oxide Donors; Oxidation-Reduction; Protein Processing, Post-Translational; Rats; S-Nitrosothiols; Selenocysteine; Thioredoxin Reductase 1 | 2016 |
Removal of the 5-nitro-2-pyridine-sulfenyl protecting group from selenocysteine and cysteine by ascorbolysis.
Topics: Ascorbic Acid; Cysteine; Disulfides; Hydrogen-Ion Concentration; Hydrolysis; Pyridines; Selenocysteine; Time Factors; Trifluoroacetic Acid | 2016 |
The role of electrostatics in TrxR electron transfer mechanism: A computational approach.
Topics: Amino Acid Motifs; Coenzymes; Cysteine; Electron Transport; Electrons; Flavin-Adenine Dinucleotide; Humans; Hydrogen-Ion Concentration; Molecular Dynamics Simulation; Monte Carlo Method; Mutation; Oxidation-Reduction; Poisson Distribution; Protein Domains; Protein Structure, Secondary; Selenocysteine; Static Electricity; Thioredoxin Reductase 1; Water | 2016 |
Crystal and solution structural studies of mouse phospholipid hydroperoxide glutathione peroxidase 4.
Topics: Amino Acid Sequence; Animals; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Escherichia coli; Gene Expression; Glutathione Peroxidase; Mice; Models, Molecular; Mutation; Phospholipid Hydroperoxide Glutathione Peroxidase; Plasmids; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; Selenocysteine; Substrate Specificity | 2016 |
Recoding of the selenocysteine UGA codon by cysteine in the presence of a non-canonical tRNA
Topics: Amino Acyl-tRNA Synthetases; Anticodon; Bacterial Proteins; Codon, Terminator; Cysteine; Desulfotomaculum; Escherichia coli; Genetic Code; Models, Molecular; Mutation; Nucleic Acid Conformation; Peptide Elongation Factor Tu; Peptococcaceae; Protein Biosynthesis; Ribosomes; RNA, Transfer, Cys; Selenocysteine; Selenoproteins | 2018 |
A Protein-Capsid-Based System for Cell Delivery of Selenocysteine.
Topics: Antineoplastic Agents; Biological Transport; Capsid; Cell Line; Cell Membrane Permeability; Cysteine; Drug Carriers; Drug Delivery Systems; Drug Liberation; Humans; Multienzyme Complexes; Protein Engineering; Selenocysteine | 2018 |
Improving redox sensitivity of roGFP1 by incorporation of selenocysteine at position 147.
Topics: Antimycin A; Cysteine; Electron Transport; Glutathione; Green Fluorescent Proteins; HEK293 Cells; Humans; Hydrogen Peroxide; Mitochondria; Oxidation-Reduction; Oxidative Stress; Oxygen; Reactive Oxygen Species; Selenocysteine | 2018 |
Substitution of an Internal Disulfide Bridge with a Diselenide Enhances both Foldability and Stability of Human Insulin.
Topics: Crystallography, X-Ray; Cysteine; Disulfides; Humans; Insulin; Protein Binding; Protein Folding; Protein Stability; Protein Structure, Tertiary; Receptor, Insulin; Recombinant Proteins; Selenium; Selenocysteine; Thermodynamics | 2019 |
S-Glutathionylation of mouse selenoprotein W prevents oxidative stress-induced cell death by blocking the formation of an intramolecular disulfide bond.
Topics: Animals; Binding Sites; Cell Death; Cysteine; Disulfides; Glutaredoxins; Glutathione; Glutathione S-Transferase pi; HEK293 Cells; Humans; Mice; Oxidation-Reduction; Oxidative Stress; Protein Binding; Selenocysteine; Selenoprotein W | 2019 |
Incorporation of Ni
Topics: Bacterial Proteins; Catalytic Domain; Cobalt; Cysteine; Iron-Sulfur Proteins; Nickel; Selenocysteine; Shewanella | 2019 |
A dual attack on the peroxide bond. The common principle of peroxidatic cysteine or selenocysteine residues.
Topics: Catalytic Domain; Cysteine; Glutathione Peroxidase; Hydrogen Peroxide; Peroxides; Peroxiredoxins; Selenocysteine | 2020 |
Can Selenoenzymes Resist Electrophilic Modification? Evidence from Thioredoxin Reductase and a Mutant Containing α-Methylselenocysteine.
Topics: Cysteine; Humans; Mutation; Oxidation-Reduction; Selenium Oxides; Selenocysteine; Selenoproteins; Thioredoxin-Disulfide Reductase; Thioredoxins | 2020 |
An intraresidue H-bonding motif in selenocysteine and cysteine, revealed by gas phase laser spectroscopy and quantum chemistry calculations.
Topics: Cysteine; Dipeptides; Hydrogen Bonding; Protein Structure, Secondary; Quantum Theory; Selenocysteine; Serine; Spectrum Analysis | 2020 |
Suppression of lipopolysaccharide-induced activation of RAW 264.7 macrophages by Se-methylseleno-l-cysteine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Cell Survival; Cysteine; Gene Expression Regulation; Lipopolysaccharides; Macrophage Activation; Mice; Molecular Structure; RAW 264.7 Cells; RNA, Messenger; Selenocysteine | 2020 |
Quantitative Proteomics Reveals UGA-Independent Misincorporation of Selenocysteine throughout the
Topics: Cysteine; Escherichia coli; Protein Biosynthesis; Proteome; Proteomics; Selenocysteine | 2021 |
Reactivity of antitumor coinage metal-based N-heterocyclic carbene complexes with cysteine and selenocysteine protein sites.
Topics: Antineoplastic Agents; Coordination Complexes; Copper; Cysteine; Density Functional Theory; Gold; Ligands; Models, Chemical; Molecular Structure; Selenocysteine; Silver; Thermodynamics | 2021 |
Intein-based Design Expands Diversity of Selenocysteine Reporters.
Topics: Codon, Terminator; Cysteine; Escherichia coli; Genes, Reporter; Inteins; Mutagenesis, Site-Directed; Recombinant Proteins; Selenocysteine; Selenoproteins | 2022 |
Selenocysteine substitutions in thiyl radical enzymes.
Topics: Cysteine; Proteomics; S-Adenosylmethionine; Selenocysteine; Selenoproteins | 2022 |
Expression of selenoproteins via genetic code expansion in mammalian cells.
Topics: Animals; Cysteine; Genetic Code; Humans; Mammals; Protein Biosynthesis; Selenocysteine; Selenoproteins | 2022 |
Chemoproteomic interrogation of selenocysteine by low-pH isoTOP-ABPP.
Topics: Animals; Cysteine; Hydrogen-Ion Concentration; Mice; Proteome; Selenium; Selenocysteine; Selenoproteins | 2022 |
Substrate Recognition by the Peptidyl-(
Topics: Catalysis; Cysteine; Oxidation-Reduction; Peptides; Selenocysteine; Substrate Specificity | 2022 |
Reprint of: Comparison of the Chemical Properties of Selenocysteine and Selenocystine with Their Sulfur Analogs.
Topics: Cysteine; Cystine; Organoselenium Compounds; Selenium; Selenocysteine; Sulfur | 2022 |
Stereoselective α-Deuteration of Serine, Cysteine, Selenocysteine, and 2,3-Diaminopropanoic Acid Derivatives.
Topics: Alcohols; Amines; beta-Alanine; Carbocysteine; Cysteine; Selenocysteine; Serine | 2022 |
SEPHS1: Its evolution, function and roles in development and diseases.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Cysteine; Mice; Phosphates; Phylogeny; Reactive Oxygen Species; Selenium; Selenocysteine | 2022 |
Concomitant selenoenzyme inhibitor exposures as etiologic contributors to disease: Implications for preventative medicine.
Topics: Cysteine; Humans; Selenium; Selenocysteine; Sulfhydryl Compounds; Sulfur | 2023 |
Chemical synthesis of per-selenocysteine human epidermal growth factor.
Topics: Cysteine; Disulfides; Epidermal Growth Factor; Humans; Peptides; Protein Folding; Selenocysteine | 2023 |
Novel Lennard-Jones Parameters for Cysteine and Selenocysteine in the AMBER Force Field.
Topics: Amino Acids; Cysteine; Humans; Molecular Dynamics Simulation; Proteins; Selenocysteine | 2023 |
Optimized methyl donor and reduced precursor degradation pathway for seleno-methylselenocysteine production in Bacillus subtilis.
Topics: Bacillus subtilis; Cysteine; Selenium; Selenocysteine; Vitamin U | 2023 |