Page last updated: 2024-08-26

selenium and methylselenic acid

selenium has been researched along with methylselenic acid in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's16 (48.48)29.6817
2010's16 (48.48)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Ganther, HE; Ip, C; Thompson, HJ; Zhu, Z1
Gromer, S; Gross, JH1
Jiang, C; Lü, J; Wang, Z1
Ganther, H; Jiang, C; Lü, J; Wang, Z1
Budunova, IV; Gasparian, AV; Lü, J; Lyakh, LA; Slaga, TJ; Yao, YJ; Yemelyanov, AY1
Dong, Y; Gao, AC; Ip, C; Marshall, JR; Zhang, H1
Abdulah, R; Koyama, H; Miyazaki, K; Nakazawa, M1
Baek, SH; Choi, KS; Ip, C; Kim, YH; Lee, JS; Ma, YB; Park, EM; Park, SY; Park, YM; Zhang, H; Zu, K1
Ip, C; Wallace, PK; Warren, MA; Wu, Y; Zu, K1
Kurasaki, K; Ogawa, S; Suzuki, KT; Suzuki, N1
Ohta, Y; Suzuki, KT; Suzuki, N1
Ohta, Y; Suzuki, KT1
Fitzgibbon, J; Goenaga-Infante, H; Joel, SP; Jüliger, S; Lister, TA1
Dong, Y; Liu, S; Zhang, H; Zhao, L; Zhu, L1
Chhabra, D; Gopalakrishna, R; Gundimeda, U; Schiffman, JE; Wong, J; Wu, A1
Chen, YC; Gandhi, UH; Mastro, AM; Novinger, LJ; Prabhu, KS; Sosnoski, DM1
Bai, J; Dong, Y; He, S; Liu, M; Quan, L; Xu, N; Yan, S; Yang, S; Zhang, G; Zhang, W; Zhu, H1
Brumaghim, JL; Ramoutar, RR1
Goenaga-Infante, H; Hopley, C; Joel, SP; Kassam, S; Stokes, E1
Cheng, WH; Luo, Y; Song, J; Tian, F; Wang, Q; Zeng, H; Zhang, S1
King, T; Null, K; Pinto, JT; Sinha, I; Sinha, R; Suckow, MA; Wolter, W1
Goenaga-Infante, H; Hiley, CT; Joel, SP; Juliger, S; Kassam, S; Maharaj, L1
Boucher, KM; Cassidy, JP; Cassidy, PB; Fain, HD; Florell, SR; Gerads, R; Grossman, D; Leachman, SA; Moos, PJ; Tran, SM1
Huang, JQ; Lei, XG; Li, JG; Li, L; Shi, J; Sun, LH; Wang, KN; Xia, XJ; Zhao, H1
Chen, C; Li, F; Liu, H; Yao, Q; Younes, M; Zhang, S1
Han, F; Huang, Z; Liu, Y; Lu, J; Sun, L; Wang, Q; Yang, Y; Zhang, H1
Wu, M; Zeng, H1
Guo, M; Li, C; Li, W; Liu, Y; Qiu, C1
Chen, PC; Guo, CH; Hsia, S; Hsieh, FC; Shih, MY1
Guo, M; Li, C; Li, W; Liu, Y; Mu, W; Qiu, C1
Cai, Z; Dong, L; Hoffmann, PR; Huang, Z; Li, J; Li, W; Ling, Q; Song, C; Zhang, Y; Zhu, C1
Cursons, RT; Jacobson, GM; Jameson, MB; Lobb, RJ1
Bosland, MC; Deng, Y; Lü, J; Schlicht, MJ1

Reviews

2 review(s) available for selenium and methylselenic acid

ArticleYear
Chemical forms of selenium for cancer prevention.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2005, Volume: 19, Issue:2-3

    Topics: Anticarcinogenic Agents; Chromatography; Chromatography, High Pressure Liquid; Cysteine; Food; Glutathione Peroxidase; Humans; Iodide Peroxidase; Mass Spectrometry; Methionine Sulfoxide Reductases; Models, Chemical; Neoplasms; Organoselenium Compounds; Selenium; Selenocysteine; Selenoprotein P; Selenoprotein W; Thioredoxin-Disulfide Reductase

2005
Antioxidant and anticancer properties and mechanisms of inorganic selenium, oxo-sulfur, and oxo-selenium compounds.
    Cell biochemistry and biophysics, 2010, Volume: 58, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; Cell Death; Dimethyl Sulfoxide; Disulfides; Humans; Methionine; Neoplasms; Organoselenium Compounds; Oxidants; Reactive Oxygen Species; Selenium; Sulfinic Acids; Sulfones; Sulfur

2010

Trials

1 trial(s) available for selenium and methylselenic acid

ArticleYear
Effect of Dietary Methylseleninic Acid and Se-Methylselenocysteine on Carcinogen-Induced, Androgen-Promoted Prostate Carcinogenesis in Rats.
    Nutrition and cancer, 2022, Volume: 74, Issue:10

    Topics: Androgens; Animals; Antioxidants; Carcinogenesis; Carcinogens; Diet; Disease Models, Animal; Humans; Male; Mice; Organoselenium Compounds; Prostate; Prostatic Neoplasms; Rats; Selenium; Selenocysteine; Selenomethionine

2022

Other Studies

30 other study(ies) available for selenium and methylselenic acid

ArticleYear
In vitro and in vivo studies of methylseleninic acid: evidence that a monomethylated selenium metabolite is critical for cancer chemoprevention.
    Cancer research, 2000, Jun-01, Volume: 60, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Comet Assay; Female; Glutathione Peroxidase; Liver; Lyases; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasms, Experimental; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Selenium; Thioredoxin-Disulfide Reductase; Tissue Distribution; Tumor Cells, Cultured

2000
Methylseleninate is a substrate rather than an inhibitor of mammalian thioredoxin reductase. Implications for the antitumor effects of selenium.
    The Journal of biological chemistry, 2002, Mar-22, Volume: 277, Issue:12

    Topics: Animals; Antineoplastic Agents; Catalysis; Dithionitrobenzoic Acid; Drosophila melanogaster; Glutathione Disulfide; Glutathione Reductase; Humans; Hydrogen Peroxide; Kinetics; Mass Spectrometry; Mice; Models, Biological; Models, Chemical; Organoselenium Compounds; Peroxidase; Placenta; Plasmodium falciparum; Protein Binding; Protein Structure, Tertiary; Selenium; Selenocysteine; Silver; Substrate Specificity; Thioredoxin-Disulfide Reductase; Thioredoxins; Time Factors

2002
Induction of caspase-mediated apoptosis and cell-cycle G1 arrest by selenium metabolite methylselenol.
    Molecular carcinogenesis, 2002, Volume: 34, Issue:3

    Topics: Apoptosis; Carbon-Sulfur Lyases; Caspases; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; G1 Phase; Humans; Methanol; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Organoselenium Compounds; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; S Phase; Selenium; Selenomethionine

2002
Distinct effects of methylseleninic acid versus selenite on apoptosis, cell cycle, and protein kinase pathways in DU145 human prostate cancer cells.
    Molecular cancer therapeutics, 2002, Volume: 1, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Death; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; DNA Fragmentation; G1 Phase; Humans; Immunoblotting; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; Organoselenium Compounds; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Protein Kinases; S Phase; Selenium; Sodium Selenite; Superoxides; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins

2002
Selenium compounds inhibit I kappa B kinase (IKK) and nuclear factor-kappa B (NF-kappa B) in prostate cancer cells.
    Molecular cancer therapeutics, 2002, Volume: 1, Issue:12

    Topics: Active Transport, Cell Nucleus; Adenoviridae; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Nucleus; Cytosol; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; I-kappa B Kinase; Luciferases; Male; NF-kappa B; Organoselenium Compounds; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Protein Binding; Protein Serine-Threonine Kinases; Selenium; Time Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured

2002
Androgen receptor signaling intensity is a key factor in determining the sensitivity of prostate cancer cells to selenium inhibition of growth and cancer-specific biomarkers.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:7

    Topics: Biomarkers, Tumor; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Luciferases; Male; Organoselenium Compounds; Prostatic Neoplasms; Receptors, Androgen; Selenium; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured

2005
Neural network-based analysis of thiol proteomics data in identifying potential selenium targets.
    Preparative biochemistry & biotechnology, 2006, Volume: 36, Issue:1

    Topics: Antineoplastic Agents; Biotin; Cell Line, Tumor; Electrophoresis, Gel, Two-Dimensional; Ethylenediamines; Humans; Male; Neural Networks, Computer; Organoselenium Compounds; Oxidation-Reduction; Prostatic Neoplasms; Proteins; Proteome; Proteomics; Selenium; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfhydryl Compounds

2006
Delineating the mechanism by which selenium deactivates Akt in prostate cancer cells.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:2

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Antineoplastic Agents; Calcineurin; Calcium; Cell Membrane; Humans; Male; Organoselenium Compounds; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphorylation; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Selenium; Threonine

2006
Metabolic transformation of methylseleninic acid through key selenium intermediate selenide.
    Toxicology and applied pharmacology, 2006, Sep-01, Volume: 215, Issue:2

    Topics: Animals; Antioxidants; Biotransformation; Erythrocytes; Injections, Intravenous; Isotopes; Male; Organoselenium Compounds; Rats; Rats, Wistar; Selenium; Selenium Compounds; Tissue Distribution

2006
Availability and metabolism of 77Se-methylseleninic acid compared simultaneously with those of three related selenocompounds.
    Toxicology and applied pharmacology, 2006, Nov-15, Volume: 217, Issue:1

    Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Dealkylation; Isotopes; Male; Mass Spectrometry; Methylation; Organoselenium Compounds; Rats; Selenic Acid; Selenium; Selenium Compounds; Sodium Selenite; Time Factors; Tissue Distribution

2006
Methylation and demethylation of intermediates selenide and methylselenol in the metabolism of selenium.
    Toxicology and applied pharmacology, 2008, Jan-15, Volume: 226, Issue:2

    Topics: Animals; Glutathione; In Vitro Techniques; Isotopes; Kidney; Liver; Lung; Male; Methanol; Methylation; Organ Specificity; Organoselenium Compounds; Oxides; Rats; Rats, Wistar; Selenious Acid; Selenium; Selenium Compounds

2008
Chemosensitization of B-cell lymphomas by methylseleninic acid involves nuclear factor-kappaB inhibition and the rapid generation of other selenium species.
    Cancer research, 2007, Nov-15, Volume: 67, Issue:22

    Topics: Antineoplastic Agents; Apoptosis; Cell Death; Cell Line, Tumor; Cell Survival; Comet Assay; DNA Damage; Humans; Lymphoma, B-Cell; NF-kappa B; Organoselenium Compounds; Selenium; Time Factors; Transfection

2007
Kruppel-like factor 4 is a novel mediator of selenium in growth inhibition.
    Molecular cancer research : MCR, 2008, Volume: 6, Issue:2

    Topics: Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Male; Organoselenium Compounds; Prostatic Neoplasms; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; RNA, Messenger; RNA, Small Interfering; Selenium; Transcription, Genetic; Up-Regulation

2008
Locally generated methylseleninic acid induces specific inactivation of protein kinase C isoenzymes: relevance to selenium-induced apoptosis in prostate cancer cells.
    The Journal of biological chemistry, 2008, Dec-12, Volume: 283, Issue:50

    Topics: Apoptosis; Catalytic Domain; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Humans; Isoenzymes; Male; Organoselenium Compounds; Oxygen; Prostatic Neoplasms; Protein Kinase C; RNA, Small Interfering; Selenium

2008
Selenium modifies the osteoblast inflammatory stress response to bone metastatic breast cancer.
    Carcinogenesis, 2009, Volume: 30, Issue:11

    Topics: Animals; Bone Neoplasms; Breast Neoplasms; Cell Communication; Cell Differentiation; Cell Line, Tumor; Chemokine CCL2; Culture Media, Conditioned; Cyclooxygenase 2; Female; Humans; Inflammation; Interleukin-6; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Organoselenium Compounds; Osteoblasts; Selenium

2009
beta-Catenin/TCF pathway plays a vital role in selenium induced-growth inhibition and apoptosis in esophageal squamous cell carcinoma (ESCC) cells.
    Cancer letters, 2010, Oct-01, Volume: 296, Issue:1

    Topics: Annexin A5; Apoptosis; beta Catenin; Cell Division; Cell Line, Tumor; Colony-Forming Units Assay; DNA Primers; Esophageal Neoplasms; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Neoplasms, Squamous Cell; Organoselenium Compounds; Polymerase Chain Reaction; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myc; Selenium; Survivin; T Cell Transcription Factor 1

2010
Capabilities of HPLC with APEX-Q nebulisation ICP-MS and ESI MS/MS to compare selenium uptake and speciation of non-malignant with different B cell lymphoma lines.
    Analytical and bioanalytical chemistry, 2011, Volume: 399, Issue:5

    Topics: Cell Line; Chromatography, High Pressure Liquid; Humans; Lymphoma, B-Cell; Mass Spectrometry; Organoselenium Compounds; Selenium; Tissue Distribution

2011
Encapsulation of selenium in chitosan nanoparticles improves selenium availability and protects cells from selenium-induced DNA damage response.
    The Journal of nutritional biochemistry, 2011, Volume: 22, Issue:12

    Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; Chitosan; DNA Damage; DNA-Binding Proteins; Fluorescent Antibody Technique; HCT116 Cells; Humans; Nanoparticles; Organoselenium Compounds; Phosphorylation; Protein Serine-Threonine Kinases; Selenium; Sodium Selenite; Tumor Suppressor Proteins

2011
Methylseleninic acid downregulates hypoxia-inducible factor-1α in invasive prostate cancer.
    International journal of cancer, 2012, Mar-15, Volume: 130, Issue:6

    Topics: Animals; Apoptosis; Cell Line, Tumor; Down-Regulation; Glucose Transporter Type 1; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lung; Lung Neoplasms; Male; Neoplasm Metastasis; Organoselenium Compounds; Procollagen-Proline Dioxygenase; Prostatic Neoplasms; Rats; Rats, Wistar; Selenium; Vascular Endothelial Growth Factor A

2012
Methylseleninic acid inhibits HDAC activity in diffuse large B-cell lymphoma cell lines.
    Cancer chemotherapy and pharmacology, 2011, Volume: 68, Issue:3

    Topics: Blotting, Western; Cell Line, Tumor; Cystine; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lymphoma, B-Cell; Organoselenium Compounds; Selenium; Vascular Endothelial Growth Factor A

2011
Selenium for the prevention of cutaneous melanoma.
    Nutrients, 2013, Mar-07, Volume: 5, Issue:3

    Topics: Animals; Cell Cycle; Cell Line, Tumor; Cell Survival; Female; Human Growth Hormone; Humans; Male; Melanoma; Mice; Mice, Transgenic; Organoselenium Compounds; Proportional Hazards Models; RNA; Selenium; Selenocysteine; Skin Neoplasms; Sodium Selenite; Ultraviolet Rays

2013
Porcine serum can be biofortified with selenium to inhibit proliferation of three types of human cancer cells.
    The Journal of nutrition, 2013, Volume: 143, Issue:7

    Topics: Animal Feed; Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Culture Media; Dietary Supplements; DNA-Binding Proteins; Down-Regulation; Humans; Muscle Proteins; Organoselenium Compounds; Selenium; Selenoproteins; Serum; Sodium Selenite; Swine; Up-Regulation

2013
Reduced selenium-binding protein 1 in breast cancer correlates with poor survival and resistance to the anti-proliferative effects of selenium.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Resistance, Neoplasm; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Staging; Organoselenium Compounds; Receptors, Estrogen; Receptors, Progesterone; Selenium; Selenium-Binding Proteins; Survival Analysis; Tumor Suppressor Protein p53

2013
[Effects of selenium compounds on proliferation, migration and adhesion of HeLa cells].
    Wei sheng yan jiu = Journal of hygiene research, 2015, Volume: 44, Issue:2

    Topics: Anticarcinogenic Agents; Cell Movement; HeLa Cells; Humans; Organoselenium Compounds; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine

2015
The Inhibitory Efficacy of Methylseleninic Acid Against Colon Cancer Xenografts in C57BL/6 Mice.
    Nutrition and cancer, 2015, Volume: 67, Issue:5

    Topics: Animals; Blotting, Western; Caspase 3; Cell Proliferation; Colonic Neoplasms; Drug Evaluation, Preclinical; Glutathione Peroxidase; Heterografts; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Models, Animal; Organoselenium Compounds; Selenium; Tumor Necrosis Factor-alpha

2015
Protective Role of Selenium Compounds on the Proliferation, Apoptosis, and Angiogenesis of a Canine Breast Cancer Cell Line.
    Biological trace element research, 2016, Volume: 169, Issue:1

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dogs; Female; Mammary Neoplasms, Animal; Organoselenium Compounds; Selenium; Selenium Compounds

2016
Effects of Selenium Yeast on Oxidative Stress, Growth Inhibition, and Apoptosis in Human Breast Cancer Cells.
    International journal of medical sciences, 2015, Volume: 12, Issue:9

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Female; Glutathione Peroxidase; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial; Organoselenium Compounds; Oxidative Stress; Reactive Oxygen Species; Selenium; Selenocysteine; Superoxide Dismutase; Yeasts

2015
Selenium Plays a Protective Role in Staphylococcus aureus-Induced Endometritis in the Uterine Tissue of Rats.
    Biological trace element research, 2016, Volume: 173, Issue:2

    Topics: Animals; Endometriosis; Female; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Selenium; Selenocysteine; Staphylococcal Infections; Staphylococcus aureus; Uterus

2016
Methylseleninic Acid Provided at Nutritional Selenium Levels Inhibits Angiogenesis by Down-regulating Integrin β3 Signaling.
    Scientific reports, 2017, 08-25, Volume: 7, Issue:1

    Topics: Angiogenesis Inducing Agents; Animals; Cell Adhesion; Cell Movement; Chick Embryo; Chorioallantoic Membrane; Down-Regulation; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Integrin beta3; NF-kappa B; Nutritional Physiological Phenomena; Organoselenium Compounds; Proto-Oncogene Proteins c-akt; Selenium; Signal Transduction

2017
The Interaction of Selenium with Chemotherapy and Radiation on Normal and Malignant Human Mononuclear Blood Cells.
    International journal of molecular sciences, 2018, Oct-15, Volume: 19, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; DNA Damage; Drug Interactions; Endoplasmic Reticulum Stress; Glutathione; Humans; Leukocytes, Mononuclear; Organoselenium Compounds; Radiation; Selenium

2018